1O0XA

Crystal structure of methionine aminopeptidase (tm1478) from thermotoga maritima at 1.90 a resolution
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
249
structure length
249
Chain Sequence
MIRIKTPSEIEKMKKAGKAVAVALREVRKVIVPGKTAWDVETLVLEIFKKLRVKPAFKGYGGYKYATCVSVNEEVVHGLPLKEKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVGETDERGKELVRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGRELHEDPQIPNYGTPGTGVVLRKGMTLAIEPMVSEGDWRVVVKEDGWTAVTVDGSRCAHFEHTILITENGAEILTKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution.
pubmed doi rcsb
source organism Thermotoga maritima
total genus 84
structure length 249
sequence length 249
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2002-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1o0xA00
1Y1NA 5D6FA 1N51A 5CDLA 4EGEA 1QZYA 2ZSGA 2BWVA 1WBQA 4S00A 4FLJA 4U71A 5E5BA 1WY2A 2ADUA 4RZYA 3MR1A 2BB7A 4IECA 2Q92A 3CB6A 2Q8KA 2V3ZA 4Z7MA 1A16A 2OAZA 3L24A 2NQ7A 2G6PA 2EVOA 4ZNGA 1PV9A 1YW9A 1QXYA 4KM3A 4FO8A 4IDYA 4U70A 4U69A 3RVAA 4ZWUA 2GU6A 1C27A 2EA2A 4U75A 4FKCA 4U73A 4IKUA 1XGMA 4U76A 2BWSA 4IPAA 2GG5A 4FLIA 5CDVA 2Q94A 2GG0A 2GZ5A 2BHCA 2GG8A 4MATA 2P99A 2Q93A 5CNXA 2GGCA 2BWXA 3IG4A 4U6ZA 4PV4A 1JAWA 5CLSA 4ZWOA 1XNZA 2B3HA 1XGOA 2BWYA 4IKTA 1C23A 3BITA 3MX6A 4B28A 2IW2A 3Q6DA 1BN5A 3IU8A 4R60A 3BIQA 2GU7A 1R5GA 5CIKA 5JHUA 5FCFA 1R58A 4FO7A 1WL9A 1CHMA 3IU9A 3CTZA 1C22A 2GG3A 3TAVA 2V3XA 4FUKA 1WLRA 2BH3A 2V3YA 4PNCA 4U6EA 2GG7A 1C24A 5CE6A 2B3LA 4QR8A 4IF7A 4U6WA 4ZWPA 3CB5A 1KP0A 2BHDA 2MATA 1KQ0A 2GU4A 4RGZ1 3IU7A 3PKDA 5D6EA 2DFIA 5CDEA 1BOAA 1C21A 1W2MA 3PKCA 1O0XA 3S6BA 4U1BA 1XGNA 3PKEA 3RORA 3TB5A 1QXZA 2BWWA 4RZZA 2EVMA 4S2RP 2Q96A 3L7GA 1YW7A 1B59A 3BIPA 2OKNA 1QXWA 4FLKA 2EVCA 1R5HA 3MATA 2BHBA 1WL6A 4A6WA 3FMQA 1M35A 2BHAA 4FLLA 2GTXA 2GU5A 5JI6A 2BWUA 1B6AA 2GG9A 4U6JA 1YVMA 1YJ3A 4JUQA 2GA2A 2GG2A 4HXXA 4S01A 1W7VA 2V6CA 2B3KA 4U6CA 3FM3A 2BN7A 3D27A 1XGSA 2NQ6A 2EA4A 2GGBA 5FCHA 1WN1A 2P9AA 2HOWA 5JFRA 3PKAA 1WKMA 3PKBA 3FMRA 1MATA 4IKSA 2Q95A 1KQ9A 1YW8A 4IU6A 2BWTA 4IKRA 2P98A 4A6VA 4S2TP 4OOKA
chains in the Genus database with same CATH superfamily
1Y1NA 5D6FA 1N51A 5CDLA 4EGEA 1QZYA 2ZSGA 2BWVA 1WBQA 4S00A 4FLJA 4U71A 5E5BA 1WY2A 2ADUA 4RZYA 3MR1A 2BB7A 4IECA 2Q92A 3CB6A 2Q8KA 2V3ZA 4Z7MA 1A16A 2OAZA 3L24A 2NQ7A 2G6PA 2EVOA 4ZNGA 1PV9A 1YW9A 1QXYA 4KM3A 4FO8A 4IDYA 4U70A 4U69A 3RVAA 4ZWUA 2GU6A 1C27A 2EA2A 4U75A 4FKCA 4U73A 4IKUA 1XGMA 4U76A 2BWSA 4IPAA 2GG5A 4FLIA 5CDVA 2Q94A 2GG0A 2GZ5A 2BHCA 2GG8A 4MATA 2P99A 2Q93A 5CNXA 2GGCA 2BWXA 3IG4A 4U6ZA 4PV4A 1JAWA 5CLSA 4ZWOA 1XNZA 2B3HA 1XGOA 2BWYA 4IKTA 1C23A 3BITA 3MX6A 4B28A 2IW2A 3Q6DA 1BN5A 3IU8A 4R60A 3BIQA 2GU7A 1R5GA 5CIKA 5JHUA 5FCFA 1R58A 4FO7A 1WL9A 1CHMA 3IU9A 3CTZA 1C22A 2GG3A 3TAVA 2V3XA 4FUKA 1WLRA 2BH3A 2V3YA 4PNCA 4U6EA 2GG7A 1C24A 5CE6A 2B3LA 4QR8A 4IF7A 4U6WA 4ZWPA 3CB5A 1KP0A 2BHDA 2MATA 1KQ0A 2GU4A 4RGZ1 3IU7A 3PKDA 5D6EA 2DFIA 5CDEA 1BOAA 1C21A 1W2MA 3PKCA 1O0XA 3S6BA 4U1BA 1XGNA 3PKEA 3RORA 3TB5A 1QXZA 2BWWA 4RZZA 2EVMA 4S2RP 2Q96A 3L7GA 1YW7A 1B59A 3BIPA 2OKNA 1QXWA 4FLKA 2EVCA 1R5HA 3MATA 2BHBA 1WL6A 4A6WA 3FMQA 1M35A 2BHAA 4FLLA 2GTXA 2GU5A 5JI6A 2BWUA 1B6AA 2GG9A 4U6JA 1YVMA 1YJ3A 4JUQA 2GA2A 2GG2A 4HXXA 4S01A 1W7VA 2V6CA 2B3KA 4U6CA 3FM3A 2BN7A 3D27A 1XGSA 2NQ6A 2EA4A 2GGBA 5FCHA 1WN1A 2P9AA 2HOWA 5JFRA 3PKAA 1WKMA 3PKBA 3FMRA 1MATA 4IKSA 2Q95A 1KQ9A 1YW8A 4IU6A 2BWTA 4IKRA 2P98A 4A6VA 4S2TP 4OOKA
chains in the Genus database with same CATH topology
1Y1NA 5D6FA 1N51A 5CDLA 4EGEA 1QZYA 2ZSGA 2BWVA 1WBQA 4S00A 4FLJA 4U71A 5E5BA 1WY2A 2ADUA 4RZYA 3MR1A 2BB7A 4IECA 2Q92A 3CB6A 2Q8KA 2V3ZA 4Z7MA 1A16A 2OAZA 3L24A 2NQ7A 2G6PA 2EVOA 4ZNGA 1PV9A 1YW9A 1QXYA 4KM3A 4FO8A 4IDYA 4U70A 4U69A 3RVAA 4ZWUA 2GU6A 1C27A 2EA2A 4U75A 4FKCA 4U73A 4IKUA 1XGMA 4U76A 2BWSA 4IPAA 2GG5A 4FLIA 5CDVA 2Q94A 2GG0A 2GZ5A 2BHCA 2GG8A 4MATA 2P99A 2Q93A 5CNXA 2GGCA 2BWXA 3IG4A 4U6ZA 4PV4A 1JAWA 5CLSA 4ZWOA 1XNZA 2B3HA 1XGOA 2BWYA 4IKTA 1C23A 3BITA 3MX6A 4B28A 2IW2A 3Q6DA 1BN5A 3IU8A 4R60A 3BIQA 2GU7A 1R5GA 5CIKA 5JHUA 5FCFA 1R58A 4FO7A 1WL9A 1CHMA 3IU9A 3CTZA 1C22A 2GG3A 3TAVA 2V3XA 4FUKA 1WLRA 2BH3A 2V3YA 4PNCA 4U6EA 2GG7A 1C24A 5CE6A 2B3LA 4QR8A 4IF7A 4U6WA 4ZWPA 3CB5A 1KP0A 2BHDA 2MATA 1KQ0A 2GU4A 4RGZ1 3IU7A 3PKDA 5D6EA 2DFIA 5CDEA 1BOAA 1C21A 1W2MA 3PKCA 1O0XA 3S6BA 4U1BA 1XGNA 3PKEA 3RORA 3TB5A 1QXZA 2BWWA 4RZZA 2EVMA 4S2RP 2Q96A 3L7GA 1YW7A 1B59A 3BIPA 2OKNA 1QXWA 4FLKA 2EVCA 1R5HA 3MATA 2BHBA 1WL6A 4A6WA 3FMQA 1M35A 2BHAA 4FLLA 2GTXA 2GU5A 5JI6A 2BWUA 1B6AA 2GG9A 4U6JA 1YVMA 1YJ3A 4JUQA 2GA2A 2GG2A 4HXXA 4S01A 1W7VA 2V6CA 2B3KA 4U6CA 3FM3A 2BN7A 3D27A 1XGSA 2NQ6A 2EA4A 2GGBA 5FCHA 1WN1A 2P9AA 2HOWA 5JFRA 3PKAA 1WKMA 3PKBA 3FMRA 1MATA 4IKSA 2Q95A 1KQ9A 1YW8A 4IU6A 2BWTA 4IKRA 2P98A 4A6VA 4S2TP 4OOKA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1Y1N A;  5D6F A;  1N51 A;  5CDL A;  4EGE A;  1QZY A;  2ZSG A;  2BWV A;  1WBQ A;  4S00 A;  4FLJ A;  4U71 A;  5E5B A;  1WY2 A;  2ADU A;  4RZY A;  3MR1 A;  2BB7 A;  4IEC A;  2Q92 A;  3CB6 A;  2Q8K A;  2V3Z A;  4Z7M A;  1A16 A;  2OAZ A;  3L24 A;  2NQ7 A;  2G6P A;  2EVO A;  4ZNG A;  1PV9 A;  1YW9 A;  1QXY A;  4KM3 A;  4FO8 A;  4IDY A;  4U70 A;  4U69 A;  3RVA A;  4ZWU A;  2GU6 A;  1C27 A;  2EA2 A;  4U75 A;  4FKC A;  4U73 A;  4IKU A;  1XGM A;  4U76 A;  2BWS A;  4IPA A;  2GG5 A;  4FLI A;  5CDV A;  2Q94 A;  2GG0 A;  2GZ5 A;  2BHC A;  2GG8 A;  4MAT A;  2P99 A;  2Q93 A;  5CNX A;  2GGC A;  2BWX A;  3IG4 A;  4U6Z A;  4PV4 A;  1JAW A;  5CLS A;  4ZWO A;  1XNZ A;  2B3H A;  1XGO A;  2BWY A;  4IKT A;  1C23 A;  3BIT A;  3MX6 A;  4B28 A;  2IW2 A;  3Q6D A;  1BN5 A;  3IU8 A;  4R60 A;  3BIQ A;  2GU7 A;  1R5G A;  5CIK A;  5JHU A;  5FCF A;  1R58 A;  4FO7 A;  1WL9 A;  1CHM A;  3IU9 A;  3CTZ A;  1C22 A;  2GG3 A;  3TAV A;  2V3X A;  4FUK A;  1WLR A;  2BH3 A;  2V3Y A;  4PNC A;  4U6E A;  2GG7 A;  1C24 A;  5CE6 A;  2B3L A;  4QR8 A;  4IF7 A;  4U6W A;  4ZWP A;  3CB5 A;  1KP0 A;  2BHD A;  2MAT A;  1KQ0 A;  2GU4 A;  4RGZ 1;  3IU7 A;  3PKD A;  5D6E A;  2DFI A;  5CDE A;  1BOA A;  1C21 A;  1W2M A;  3PKC A;  1O0X A;  3S6B A;  4U1B A;  1XGN A;  3PKE A;  3ROR A;  3TB5 A;  1QXZ A;  2BWW A;  4RZZ A;  2EVM A;  4S2R P;  2Q96 A;  3L7G A;  1YW7 A;  1B59 A;  3BIP A;  2OKN A;  1QXW A;  4FLK A;  2EVC A;  1R5H A;  3MAT A;  2BHB A;  1WL6 A;  4A6W A;  3FMQ A;  1M35 A;  2BHA A;  4FLL A;  2GTX A;  2GU5 A;  5JI6 A;  2BWU A;  1B6A A;  2GG9 A;  4U6J A;  1YVM A;  1YJ3 A;  4JUQ A;  2GA2 A;  2GG2 A;  4HXX A;  4S01 A;  1W7V A;  2V6C A;  2B3K A;  4U6C A;  3FM3 A;  2BN7 A;  3D27 A;  1XGS A;  2NQ6 A;  2EA4 A;  2GGB A;  5FCH A;  1WN1 A;  2P9A A;  2HOW A;  5JFR A;  3PKA A;  1WKM A;  3PKB A;  3FMR A;  1MAT A;  4IKS A;  2Q95 A;  1KQ9 A;  1YW8 A;  4IU6 A;  2BWT A;  4IKR A;  2P98 A;  4A6V A;  4S2T P;  4OOK A; 
#chains in the Genus database with same CATH topology
 1Y1N A;  5D6F A;  1N51 A;  5CDL A;  4EGE A;  1QZY A;  2ZSG A;  2BWV A;  1WBQ A;  4S00 A;  4FLJ A;  4U71 A;  5E5B A;  1WY2 A;  2ADU A;  4RZY A;  3MR1 A;  2BB7 A;  4IEC A;  2Q92 A;  3CB6 A;  2Q8K A;  2V3Z A;  4Z7M A;  1A16 A;  2OAZ A;  3L24 A;  2NQ7 A;  2G6P A;  2EVO A;  4ZNG A;  1PV9 A;  1YW9 A;  1QXY A;  4KM3 A;  4FO8 A;  4IDY A;  4U70 A;  4U69 A;  3RVA A;  4ZWU A;  2GU6 A;  1C27 A;  2EA2 A;  4U75 A;  4FKC A;  4U73 A;  4IKU A;  1XGM A;  4U76 A;  2BWS A;  4IPA A;  2GG5 A;  4FLI A;  5CDV A;  2Q94 A;  2GG0 A;  2GZ5 A;  2BHC A;  2GG8 A;  4MAT A;  2P99 A;  2Q93 A;  5CNX A;  2GGC A;  2BWX A;  3IG4 A;  4U6Z A;  4PV4 A;  1JAW A;  5CLS A;  4ZWO A;  1XNZ A;  2B3H A;  1XGO A;  2BWY A;  4IKT A;  1C23 A;  3BIT A;  3MX6 A;  4B28 A;  2IW2 A;  3Q6D A;  1BN5 A;  3IU8 A;  4R60 A;  3BIQ A;  2GU7 A;  1R5G A;  5CIK A;  5JHU A;  5FCF A;  1R58 A;  4FO7 A;  1WL9 A;  1CHM A;  3IU9 A;  3CTZ A;  1C22 A;  2GG3 A;  3TAV A;  2V3X A;  4FUK A;  1WLR A;  2BH3 A;  2V3Y A;  4PNC A;  4U6E A;  2GG7 A;  1C24 A;  5CE6 A;  2B3L A;  4QR8 A;  4IF7 A;  4U6W A;  4ZWP A;  3CB5 A;  1KP0 A;  2BHD A;  2MAT A;  1KQ0 A;  2GU4 A;  4RGZ 1;  3IU7 A;  3PKD A;  5D6E A;  2DFI A;  5CDE A;  1BOA A;  1C21 A;  1W2M A;  3PKC A;  1O0X A;  3S6B A;  4U1B A;  1XGN A;  3PKE A;  3ROR A;  3TB5 A;  1QXZ A;  2BWW A;  4RZZ A;  2EVM A;  4S2R P;  2Q96 A;  3L7G A;  1YW7 A;  1B59 A;  3BIP A;  2OKN A;  1QXW A;  4FLK A;  2EVC A;  1R5H A;  3MAT A;  2BHB A;  1WL6 A;  4A6W A;  3FMQ A;  1M35 A;  2BHA A;  4FLL A;  2GTX A;  2GU5 A;  5JI6 A;  2BWU A;  1B6A A;  2GG9 A;  4U6J A;  1YVM A;  1YJ3 A;  4JUQ A;  2GA2 A;  2GG2 A;  4HXX A;  4S01 A;  1W7V A;  2V6C A;  2B3K A;  4U6C A;  3FM3 A;  2BN7 A;  3D27 A;  1XGS A;  2NQ6 A;  2EA4 A;  2GGB A;  5FCH A;  1WN1 A;  2P9A A;  2HOW A;  5JFR A;  3PKA A;  1WKM A;  3PKB A;  3FMR A;  1MAT A;  4IKS A;  2Q95 A;  1KQ9 A;  1YW8 A;  4IU6 A;  2BWT A;  4IKR A;  2P98 A;  4A6V A;  4S2T P;  4OOK A; 
#chains in the Genus database with same CATH homology
 1Y1N A;  5D6F A;  1N51 A;  5CDL A;  4EGE A;  1QZY A;  2ZSG A;  2BWV A;  1WBQ A;  4S00 A;  4FLJ A;  4U71 A;  5E5B A;  1WY2 A;  2ADU A;  4RZY A;  3MR1 A;  2BB7 A;  4IEC A;  2Q92 A;  3CB6 A;  2Q8K A;  2V3Z A;  4Z7M A;  1A16 A;  2OAZ A;  3L24 A;  2NQ7 A;  2G6P A;  2EVO A;  4ZNG A;  1PV9 A;  1YW9 A;  1QXY A;  4KM3 A;  4FO8 A;  4IDY A;  4U70 A;  4U69 A;  3RVA A;  4ZWU A;  2GU6 A;  1C27 A;  2EA2 A;  4U75 A;  4FKC A;  4U73 A;  4IKU A;  1XGM A;  4U76 A;  2BWS A;  4IPA A;  2GG5 A;  4FLI A;  5CDV A;  2Q94 A;  2GG0 A;  2GZ5 A;  2BHC A;  2GG8 A;  4MAT A;  2P99 A;  2Q93 A;  5CNX A;  2GGC A;  2BWX A;  3IG4 A;  4U6Z A;  4PV4 A;  1JAW A;  5CLS A;  4ZWO A;  1XNZ A;  2B3H A;  1XGO A;  2BWY A;  4IKT A;  1C23 A;  3BIT A;  3MX6 A;  4B28 A;  2IW2 A;  3Q6D A;  1BN5 A;  3IU8 A;  4R60 A;  3BIQ A;  2GU7 A;  1R5G A;  5CIK A;  5JHU A;  5FCF A;  1R58 A;  4FO7 A;  1WL9 A;  1CHM A;  3IU9 A;  3CTZ A;  1C22 A;  2GG3 A;  3TAV A;  2V3X A;  4FUK A;  1WLR A;  2BH3 A;  2V3Y A;  4PNC A;  4U6E A;  2GG7 A;  1C24 A;  5CE6 A;  2B3L A;  4QR8 A;  4IF7 A;  4U6W A;  4ZWP A;  3CB5 A;  1KP0 A;  2BHD A;  2MAT A;  1KQ0 A;  2GU4 A;  4RGZ 1;  3IU7 A;  3PKD A;  5D6E A;  2DFI A;  5CDE A;  1BOA A;  1C21 A;  1W2M A;  3PKC A;  1O0X A;  3S6B A;  4U1B A;  1XGN A;  3PKE A;  3ROR A;  3TB5 A;  1QXZ A;  2BWW A;  4RZZ A;  2EVM A;  4S2R P;  2Q96 A;  3L7G A;  1YW7 A;  1B59 A;  3BIP A;  2OKN A;  1QXW A;  4FLK A;  2EVC A;  1R5H A;  3MAT A;  2BHB A;  1WL6 A;  4A6W A;  3FMQ A;  1M35 A;  2BHA A;  4FLL A;  2GTX A;  2GU5 A;  5JI6 A;  2BWU A;  1B6A A;  2GG9 A;  4U6J A;  1YVM A;  1YJ3 A;  4JUQ A;  2GA2 A;  2GG2 A;  4HXX A;  4S01 A;  1W7V A;  2V6C A;  2B3K A;  4U6C A;  3FM3 A;  2BN7 A;  3D27 A;  1XGS A;  2NQ6 A;  2EA4 A;  2GGB A;  5FCH A;  1WN1 A;  2P9A A;  2HOW A;  5JFR A;  3PKA A;  1WKM A;  3PKB A;  3FMR A;  1MAT A;  4IKS A;  2Q95 A;  1KQ9 A;  1YW8 A;  4IU6 A;  2BWT A;  4IKR A;  2P98 A;  4A6V A;  4S2T P;  4OOK A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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