1XNZA

Crystal structure of mn(ii) form of e. coli. methionine aminopeptidase in complex with 5-(2-chlorophenyl)furan-2-carboxylic acid
Total Genus 90
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Metalloform-Selective Inhibitors of Escherichia coli Methionine Aminopeptidase and X-ray Structure of a Mn(II)-Form Enzyme Complexed with an Inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Methionine aminopeptidase
total genus 90
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-10-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1xnzA00
4FUKA 4IKUA 4U70A 5JI6A 4U6WA 1QXWA 3TB5A 2BWXA 2B3KA 2B3LA 3FMRA 3IU9A 3CB6A 4IKRA 1PV9A 3D27A 4U76A 5CDLA 2V3XA 4A6VA 1KQ9A 2BWYA 2GA2A 1YJ3A 1QZYA 4IECA 4ZWOA 1XGSA 2P98A 3FMQA 1C24A 4U6CA 1CHMA 1KP0A 4FKCA 1JAWA 2BH3A 3RORA 2GGCA 3CTZA 4FLLA 1WLRA 3CB5A 2IW2A 3IU7A 2GG9A 4S00A 5D6FA 1W2MA 2GG8A 1O0XA 2Q8KA 4IF7A 4U6ZA 2GZ5A 2DFIA 4MATA 3S6BA 3L7GA 3MR1A 1XGOA 2Q93A 4FO8A 2EA2A 1KQ0A 4FLIA 4IDYA 1XGMA 1R5GA 2BWSA 3BIPA 2BHAA 1A16A 3IU8A 2GGBA 4RZZA 3TAVA 4PNCA 3MATA 2ADUA 4ZNGA 5CDVA 2EA4A 4U73A 2Q95A 1QXZA 2G6PA 4U71A 2GU6A 4ZWUA 2EVOA 1XGNA 2GG7A 4JUQA 4B28A 4U6JA 3MX6A 4S01A 2BN7A 4FLKA 3PKCA 3FM3A 1WKMA 2OKNA 4RGZ1 3PKAA 5CLSA 2EVMA 2NQ7A 5JHUA 1WL6A 2Q96A 5FCFA 5CDEA 2OAZA 1WN1A 4A6WA 1BN5A 1MATA 2GG2A 1R5HA 3BITA 4EGEA 2GG5A 4IU6A 1C23A 4OOKA 5CE6A 1YW8A 2HOWA 2V3ZA 2BWTA 3IG4A 4ZWPA 2BWUA 3PKBA 1WY2A 4S2RP 4U6EA 3Q6DA 2P99A 2GU5A 1C27A 2P9AA 4Z7MA 4U69A 2BB7A 4HXXA 2ZSGA 4IPAA 2Q94A 4PV4A 5CNXA 1WL9A 4QR8A 1WBQA 1YW9A 2MATA 2NQ6A 1R58A 4FLJA 1C21A 3RVAA 1C22A 1W7VA 4FO7A 2V6CA 4U75A 1M35A 2BHBA 2B3HA 1N51A 5CIKA 2BWWA 2V3YA 2GU7A 4U1BA 5E5BA 1B59A 2BWVA 1B6AA 3PKDA 2GU4A 1QXYA 2Q92A 3L24A 4KM3A 2GG3A 4S2TP 2EVCA 5D6EA 1YW7A 5FCHA 5JFRA 2GG0A 4IKTA 3PKEA 2BHDA 3BIQA 4IKSA 1YVMA 4RZYA 1Y1NA 1XNZA 4R60A 2BHCA 1BOAA 2GTXA
chains in the Genus database with same CATH superfamily
4FUKA 4IKUA 4U70A 5JI6A 4U6WA 1QXWA 3TB5A 2BWXA 2B3KA 2B3LA 3FMRA 3IU9A 3CB6A 4IKRA 1PV9A 3D27A 4U76A 5CDLA 2V3XA 4A6VA 1KQ9A 2BWYA 2GA2A 1YJ3A 1QZYA 4IECA 4ZWOA 1XGSA 2P98A 3FMQA 1C24A 4U6CA 1CHMA 1KP0A 4FKCA 1JAWA 2BH3A 3RORA 2GGCA 3CTZA 4FLLA 1WLRA 3CB5A 2IW2A 3IU7A 2GG9A 4S00A 5D6FA 1W2MA 2GG8A 1O0XA 2Q8KA 4IF7A 4U6ZA 2GZ5A 2DFIA 4MATA 3S6BA 3L7GA 3MR1A 1XGOA 2Q93A 4FO8A 2EA2A 1KQ0A 4FLIA 4IDYA 1XGMA 1R5GA 2BWSA 3BIPA 2BHAA 1A16A 3IU8A 2GGBA 4RZZA 3TAVA 4PNCA 3MATA 2ADUA 4ZNGA 5CDVA 2EA4A 4U73A 2Q95A 1QXZA 2G6PA 4U71A 2GU6A 4ZWUA 2EVOA 1XGNA 2GG7A 4JUQA 4B28A 4U6JA 3MX6A 4S01A 2BN7A 4FLKA 3PKCA 3FM3A 1WKMA 2OKNA 4RGZ1 3PKAA 5CLSA 2EVMA 2NQ7A 5JHUA 1WL6A 2Q96A 5FCFA 5CDEA 2OAZA 1WN1A 4A6WA 1BN5A 1MATA 2GG2A 1R5HA 3BITA 4EGEA 2GG5A 4IU6A 1C23A 4OOKA 5CE6A 1YW8A 2HOWA 2V3ZA 2BWTA 3IG4A 4ZWPA 2BWUA 3PKBA 1WY2A 4S2RP 4U6EA 3Q6DA 2P99A 2GU5A 1C27A 2P9AA 4Z7MA 4U69A 2BB7A 4HXXA 2ZSGA 4IPAA 2Q94A 4PV4A 5CNXA 1WL9A 4QR8A 1WBQA 1YW9A 2MATA 2NQ6A 1R58A 4FLJA 1C21A 3RVAA 1C22A 1W7VA 4FO7A 2V6CA 4U75A 1M35A 2BHBA 2B3HA 1N51A 5CIKA 2BWWA 2V3YA 2GU7A 4U1BA 5E5BA 1B59A 2BWVA 1B6AA 3PKDA 2GU4A 1QXYA 2Q92A 3L24A 4KM3A 2GG3A 4S2TP 2EVCA 5D6EA 1YW7A 5FCHA 5JFRA 2GG0A 4IKTA 3PKEA 2BHDA 3BIQA 4IKSA 1YVMA 4RZYA 1Y1NA 1XNZA 4R60A 2BHCA 1BOAA 2GTXA
chains in the Genus database with same CATH topology
4FUKA 4IKUA 4U70A 5JI6A 4U6WA 1QXWA 3TB5A 2BWXA 2B3KA 2B3LA 3FMRA 3IU9A 3CB6A 4IKRA 1PV9A 3D27A 4U76A 5CDLA 2V3XA 4A6VA 1KQ9A 2BWYA 2GA2A 1YJ3A 1QZYA 4IECA 4ZWOA 1XGSA 2P98A 3FMQA 1C24A 4U6CA 1CHMA 1KP0A 4FKCA 1JAWA 2BH3A 3RORA 2GGCA 3CTZA 4FLLA 1WLRA 3CB5A 2IW2A 3IU7A 2GG9A 4S00A 5D6FA 1W2MA 2GG8A 1O0XA 2Q8KA 4IF7A 4U6ZA 2GZ5A 2DFIA 4MATA 3S6BA 3L7GA 3MR1A 1XGOA 2Q93A 4FO8A 2EA2A 1KQ0A 4FLIA 4IDYA 1XGMA 1R5GA 2BWSA 3BIPA 2BHAA 1A16A 3IU8A 2GGBA 4RZZA 3TAVA 4PNCA 3MATA 2ADUA 4ZNGA 5CDVA 2EA4A 4U73A 2Q95A 1QXZA 2G6PA 4U71A 2GU6A 4ZWUA 2EVOA 1XGNA 2GG7A 4JUQA 4B28A 4U6JA 3MX6A 4S01A 2BN7A 4FLKA 3PKCA 3FM3A 1WKMA 2OKNA 4RGZ1 3PKAA 5CLSA 2EVMA 2NQ7A 5JHUA 1WL6A 2Q96A 5FCFA 5CDEA 2OAZA 1WN1A 4A6WA 1BN5A 1MATA 2GG2A 1R5HA 3BITA 4EGEA 2GG5A 4IU6A 1C23A 4OOKA 5CE6A 1YW8A 2HOWA 2V3ZA 2BWTA 3IG4A 4ZWPA 2BWUA 3PKBA 1WY2A 4S2RP 4U6EA 3Q6DA 2P99A 2GU5A 1C27A 2P9AA 4Z7MA 4U69A 2BB7A 4HXXA 2ZSGA 4IPAA 2Q94A 4PV4A 5CNXA 1WL9A 4QR8A 1WBQA 1YW9A 2MATA 2NQ6A 1R58A 4FLJA 1C21A 3RVAA 1C22A 1W7VA 4FO7A 2V6CA 4U75A 1M35A 2BHBA 2B3HA 1N51A 5CIKA 2BWWA 2V3YA 2GU7A 4U1BA 5E5BA 1B59A 2BWVA 1B6AA 3PKDA 2GU4A 1QXYA 2Q92A 3L24A 4KM3A 2GG3A 4S2TP 2EVCA 5D6EA 1YW7A 5FCHA 5JFRA 2GG0A 4IKTA 3PKEA 2BHDA 3BIQA 4IKSA 1YVMA 4RZYA 1Y1NA 1XNZA 4R60A 2BHCA 1BOAA 2GTXA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4FUK A;  4IKU A;  4U70 A;  5JI6 A;  4U6W A;  1QXW A;  3TB5 A;  2BWX A;  2B3K A;  2B3L A;  3FMR A;  3IU9 A;  3CB6 A;  4IKR A;  1PV9 A;  3D27 A;  4U76 A;  5CDL A;  2V3X A;  4A6V A;  1KQ9 A;  2BWY A;  2GA2 A;  1YJ3 A;  1QZY A;  4IEC A;  4ZWO A;  1XGS A;  2P98 A;  3FMQ A;  1C24 A;  4U6C A;  1CHM A;  1KP0 A;  4FKC A;  1JAW A;  2BH3 A;  3ROR A;  2GGC A;  3CTZ A;  4FLL A;  1WLR A;  3CB5 A;  2IW2 A;  3IU7 A;  2GG9 A;  4S00 A;  5D6F A;  1W2M A;  2GG8 A;  1O0X A;  2Q8K A;  4IF7 A;  4U6Z A;  2GZ5 A;  2DFI A;  4MAT A;  3S6B A;  3L7G A;  3MR1 A;  1XGO A;  2Q93 A;  4FO8 A;  2EA2 A;  1KQ0 A;  4FLI A;  4IDY A;  1XGM A;  1R5G A;  2BWS A;  3BIP A;  2BHA A;  1A16 A;  3IU8 A;  2GGB A;  4RZZ A;  3TAV A;  4PNC A;  3MAT A;  2ADU A;  4ZNG A;  5CDV A;  2EA4 A;  4U73 A;  2Q95 A;  1QXZ A;  2G6P A;  4U71 A;  2GU6 A;  4ZWU A;  2EVO A;  1XGN A;  2GG7 A;  4JUQ A;  4B28 A;  4U6J A;  3MX6 A;  4S01 A;  2BN7 A;  4FLK A;  3PKC A;  3FM3 A;  1WKM A;  2OKN A;  4RGZ 1;  3PKA A;  5CLS A;  2EVM A;  2NQ7 A;  5JHU A;  1WL6 A;  2Q96 A;  5FCF A;  5CDE A;  2OAZ A;  1WN1 A;  4A6W A;  1BN5 A;  1MAT A;  2GG2 A;  1R5H A;  3BIT A;  4EGE A;  2GG5 A;  4IU6 A;  1C23 A;  4OOK A;  5CE6 A;  1YW8 A;  2HOW A;  2V3Z A;  2BWT A;  3IG4 A;  4ZWP A;  2BWU A;  3PKB A;  1WY2 A;  4S2R P;  4U6E A;  3Q6D A;  2P99 A;  2GU5 A;  1C27 A;  2P9A A;  4Z7M A;  4U69 A;  2BB7 A;  4HXX A;  2ZSG A;  4IPA A;  2Q94 A;  4PV4 A;  5CNX A;  1WL9 A;  4QR8 A;  1WBQ A;  1YW9 A;  2MAT A;  2NQ6 A;  1R58 A;  4FLJ A;  1C21 A;  3RVA A;  1C22 A;  1W7V A;  4FO7 A;  2V6C A;  4U75 A;  1M35 A;  2BHB A;  2B3H A;  1N51 A;  5CIK A;  2BWW A;  2V3Y A;  2GU7 A;  4U1B A;  5E5B A;  1B59 A;  2BWV A;  1B6A A;  3PKD A;  2GU4 A;  1QXY A;  2Q92 A;  3L24 A;  4KM3 A;  2GG3 A;  4S2T P;  2EVC A;  5D6E A;  1YW7 A;  5FCH A;  5JFR A;  2GG0 A;  4IKT A;  3PKE A;  2BHD A;  3BIQ A;  4IKS A;  1YVM A;  4RZY A;  1Y1N A;  1XNZ A;  4R60 A;  2BHC A;  1BOA A;  2GTX A; 
#chains in the Genus database with same CATH topology
 4FUK A;  4IKU A;  4U70 A;  5JI6 A;  4U6W A;  1QXW A;  3TB5 A;  2BWX A;  2B3K A;  2B3L A;  3FMR A;  3IU9 A;  3CB6 A;  4IKR A;  1PV9 A;  3D27 A;  4U76 A;  5CDL A;  2V3X A;  4A6V A;  1KQ9 A;  2BWY A;  2GA2 A;  1YJ3 A;  1QZY A;  4IEC A;  4ZWO A;  1XGS A;  2P98 A;  3FMQ A;  1C24 A;  4U6C A;  1CHM A;  1KP0 A;  4FKC A;  1JAW A;  2BH3 A;  3ROR A;  2GGC A;  3CTZ A;  4FLL A;  1WLR A;  3CB5 A;  2IW2 A;  3IU7 A;  2GG9 A;  4S00 A;  5D6F A;  1W2M A;  2GG8 A;  1O0X A;  2Q8K A;  4IF7 A;  4U6Z A;  2GZ5 A;  2DFI A;  4MAT A;  3S6B A;  3L7G A;  3MR1 A;  1XGO A;  2Q93 A;  4FO8 A;  2EA2 A;  1KQ0 A;  4FLI A;  4IDY A;  1XGM A;  1R5G A;  2BWS A;  3BIP A;  2BHA A;  1A16 A;  3IU8 A;  2GGB A;  4RZZ A;  3TAV A;  4PNC A;  3MAT A;  2ADU A;  4ZNG A;  5CDV A;  2EA4 A;  4U73 A;  2Q95 A;  1QXZ A;  2G6P A;  4U71 A;  2GU6 A;  4ZWU A;  2EVO A;  1XGN A;  2GG7 A;  4JUQ A;  4B28 A;  4U6J A;  3MX6 A;  4S01 A;  2BN7 A;  4FLK A;  3PKC A;  3FM3 A;  1WKM A;  2OKN A;  4RGZ 1;  3PKA A;  5CLS A;  2EVM A;  2NQ7 A;  5JHU A;  1WL6 A;  2Q96 A;  5FCF A;  5CDE A;  2OAZ A;  1WN1 A;  4A6W A;  1BN5 A;  1MAT A;  2GG2 A;  1R5H A;  3BIT A;  4EGE A;  2GG5 A;  4IU6 A;  1C23 A;  4OOK A;  5CE6 A;  1YW8 A;  2HOW A;  2V3Z A;  2BWT A;  3IG4 A;  4ZWP A;  2BWU A;  3PKB A;  1WY2 A;  4S2R P;  4U6E A;  3Q6D A;  2P99 A;  2GU5 A;  1C27 A;  2P9A A;  4Z7M A;  4U69 A;  2BB7 A;  4HXX A;  2ZSG A;  4IPA A;  2Q94 A;  4PV4 A;  5CNX A;  1WL9 A;  4QR8 A;  1WBQ A;  1YW9 A;  2MAT A;  2NQ6 A;  1R58 A;  4FLJ A;  1C21 A;  3RVA A;  1C22 A;  1W7V A;  4FO7 A;  2V6C A;  4U75 A;  1M35 A;  2BHB A;  2B3H A;  1N51 A;  5CIK A;  2BWW A;  2V3Y A;  2GU7 A;  4U1B A;  5E5B A;  1B59 A;  2BWV A;  1B6A A;  3PKD A;  2GU4 A;  1QXY A;  2Q92 A;  3L24 A;  4KM3 A;  2GG3 A;  4S2T P;  2EVC A;  5D6E A;  1YW7 A;  5FCH A;  5JFR A;  2GG0 A;  4IKT A;  3PKE A;  2BHD A;  3BIQ A;  4IKS A;  1YVM A;  4RZY A;  1Y1N A;  1XNZ A;  4R60 A;  2BHC A;  1BOA A;  2GTX A; 
#chains in the Genus database with same CATH homology
 4FUK A;  4IKU A;  4U70 A;  5JI6 A;  4U6W A;  1QXW A;  3TB5 A;  2BWX A;  2B3K A;  2B3L A;  3FMR A;  3IU9 A;  3CB6 A;  4IKR A;  1PV9 A;  3D27 A;  4U76 A;  5CDL A;  2V3X A;  4A6V A;  1KQ9 A;  2BWY A;  2GA2 A;  1YJ3 A;  1QZY A;  4IEC A;  4ZWO A;  1XGS A;  2P98 A;  3FMQ A;  1C24 A;  4U6C A;  1CHM A;  1KP0 A;  4FKC A;  1JAW A;  2BH3 A;  3ROR A;  2GGC A;  3CTZ A;  4FLL A;  1WLR A;  3CB5 A;  2IW2 A;  3IU7 A;  2GG9 A;  4S00 A;  5D6F A;  1W2M A;  2GG8 A;  1O0X A;  2Q8K A;  4IF7 A;  4U6Z A;  2GZ5 A;  2DFI A;  4MAT A;  3S6B A;  3L7G A;  3MR1 A;  1XGO A;  2Q93 A;  4FO8 A;  2EA2 A;  1KQ0 A;  4FLI A;  4IDY A;  1XGM A;  1R5G A;  2BWS A;  3BIP A;  2BHA A;  1A16 A;  3IU8 A;  2GGB A;  4RZZ A;  3TAV A;  4PNC A;  3MAT A;  2ADU A;  4ZNG A;  5CDV A;  2EA4 A;  4U73 A;  2Q95 A;  1QXZ A;  2G6P A;  4U71 A;  2GU6 A;  4ZWU A;  2EVO A;  1XGN A;  2GG7 A;  4JUQ A;  4B28 A;  4U6J A;  3MX6 A;  4S01 A;  2BN7 A;  4FLK A;  3PKC A;  3FM3 A;  1WKM A;  2OKN A;  4RGZ 1;  3PKA A;  5CLS A;  2EVM A;  2NQ7 A;  5JHU A;  1WL6 A;  2Q96 A;  5FCF A;  5CDE A;  2OAZ A;  1WN1 A;  4A6W A;  1BN5 A;  1MAT A;  2GG2 A;  1R5H A;  3BIT A;  4EGE A;  2GG5 A;  4IU6 A;  1C23 A;  4OOK A;  5CE6 A;  1YW8 A;  2HOW A;  2V3Z A;  2BWT A;  3IG4 A;  4ZWP A;  2BWU A;  3PKB A;  1WY2 A;  4S2R P;  4U6E A;  3Q6D A;  2P99 A;  2GU5 A;  1C27 A;  2P9A A;  4Z7M A;  4U69 A;  2BB7 A;  4HXX A;  2ZSG A;  4IPA A;  2Q94 A;  4PV4 A;  5CNX A;  1WL9 A;  4QR8 A;  1WBQ A;  1YW9 A;  2MAT A;  2NQ6 A;  1R58 A;  4FLJ A;  1C21 A;  3RVA A;  1C22 A;  1W7V A;  4FO7 A;  2V6C A;  4U75 A;  1M35 A;  2BHB A;  2B3H A;  1N51 A;  5CIK A;  2BWW A;  2V3Y A;  2GU7 A;  4U1B A;  5E5B A;  1B59 A;  2BWV A;  1B6A A;  3PKD A;  2GU4 A;  1QXY A;  2Q92 A;  3L24 A;  4KM3 A;  2GG3 A;  4S2T P;  2EVC A;  5D6E A;  1YW7 A;  5FCH A;  5JFR A;  2GG0 A;  4IKT A;  3PKE A;  2BHD A;  3BIQ A;  4IKS A;  1YVM A;  4RZY A;  1Y1N A;  1XNZ A;  4R60 A;  2BHC A;  1BOA A;  2GTX A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite