1Y1NA

Identification of sh3 motif in m. tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase 1B
total genus 86
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1y1nA01
4B28A 3BIQA 2GU4A 1Y1NA 4U6JA 3PKEA 1R5GA 2BWWA 2ZSGA 3IU8A 4S01A 1WLRA 4FKCA 2OKNA 5FCFA 3Q6DA 4S00A 1C24A 4U6ZA 4QR8A 5JHUA 1YW7A 2NQ7A 5D6FA 2EVOA 2GU6A 3MR1A 4U75A 3FM3A 4Z7MA 2Q93A 3RORA 2BHAA 4RZYA 3FMRA 1WN1A 4FLJA 4U73A 3BITA 1C22A 3L7GA 4FLIA 4IECA 5FCHA 1QXWA 1C27A 4S2TP 4IKSA 2GG7A 3FMQA 4U6WA 5CDVA 2P98A 2HOWA 4FLLA 2BHBA 1M35A 1KQ0A 3PKAA 1KP0A 4U70A 4IDYA 1YW9A 2BB7A 3CTZA 3L24A 4FUKA 1YJ3A 2GA2A 2BHDA 2GGBA 4FLKA 1N51A 2EA2A 2BWSA 3IG4A 3PKCA 1BOAA 1MATA 1WBQA 3D27A 2GTXA 4U6EA 4IU6A 2EVCA 1R58A 1YW8A 2Q94A 2Q96A 2B3KA 1B6AA 3PKDA 2GGCA 4OOKA 3TAVA 1W2MA 3CB6A 1QZYA 4U76A 1PV9A 2B3LA 5CDLA 2GG8A 5CIKA 2EVMA 1XGOA 2P9AA 4ZWUA 2GG9A 2OAZA 2IW2A 4ZWOA 4FO7A 1JAWA 2GG0A 4EGEA 1YVMA 2Q95A 3IU7A 2BWXA 2B3HA 4A6WA 4A6VA 1XGMA 2BHCA 4U69A 5JI6A 4U1BA 2GG5A 4R60A 1A16A 2BH3A 2GG2A 2GU7A 1WY2A 2V6CA 4IKRA 5JFRA 1QXZA 2MATA 1B59A 1QXYA 4PNCA 2ADUA 1C23A 4U71A 5CNXA 3IU9A 2BN7A 5CLSA 2BWUA 4ZNGA 2NQ6A 4RZZA 3TB5A 1R5HA 4IF7A 4ZWPA 4IPAA 4FO8A 2G6PA 2Q92A 1CHMA 2GU5A 2BWVA 3MX6A 1W7VA 1WKMA 1WL9A 2V3XA 5CE6A 1WL6A 5D6EA 4HXXA 3MATA 2BWTA 3PKBA 2DFIA 4RGZ1 4JUQA 1XGSA 2V3ZA 3CB5A 4KM3A 3S6BA 1XNZA 2EA4A 5CDEA 2GG3A 3BIPA 3RVAA 5E5BA 4IKUA 1XGNA 4U6CA 2P99A 1KQ9A 2V3YA 1O0XA 4S2RP 4MATA 1BN5A 2BWYA 1C21A 4IKTA 2Q8KA 4PV4A 2GZ5A
chains in the Genus database with same CATH superfamily
4B28A 3BIQA 2GU4A 1Y1NA 4U6JA 3PKEA 1R5GA 2BWWA 2ZSGA 3IU8A 4S01A 1WLRA 4FKCA 2OKNA 5FCFA 3Q6DA 4S00A 1C24A 4U6ZA 4QR8A 5JHUA 1YW7A 2NQ7A 5D6FA 2EVOA 2GU6A 3MR1A 4U75A 3FM3A 4Z7MA 2Q93A 3RORA 2BHAA 4RZYA 3FMRA 1WN1A 4FLJA 4U73A 3BITA 1C22A 3L7GA 4FLIA 4IECA 5FCHA 1QXWA 1C27A 4S2TP 4IKSA 2GG7A 3FMQA 4U6WA 5CDVA 2P98A 2HOWA 4FLLA 2BHBA 1M35A 1KQ0A 3PKAA 1KP0A 4U70A 4IDYA 1YW9A 2BB7A 3CTZA 3L24A 4FUKA 1YJ3A 2GA2A 2BHDA 2GGBA 4FLKA 1N51A 2EA2A 2BWSA 3IG4A 3PKCA 1BOAA 1MATA 1WBQA 3D27A 2GTXA 4U6EA 4IU6A 2EVCA 1R58A 1YW8A 2Q94A 2Q96A 2B3KA 1B6AA 3PKDA 2GGCA 4OOKA 3TAVA 1W2MA 3CB6A 1QZYA 4U76A 1PV9A 2B3LA 5CDLA 2GG8A 5CIKA 2EVMA 1XGOA 2P9AA 4ZWUA 2GG9A 2OAZA 2IW2A 4ZWOA 4FO7A 1JAWA 2GG0A 4EGEA 1YVMA 2Q95A 3IU7A 2BWXA 2B3HA 4A6WA 4A6VA 1XGMA 2BHCA 4U69A 5JI6A 4U1BA 2GG5A 4R60A 1A16A 2BH3A 2GG2A 2GU7A 1WY2A 2V6CA 4IKRA 5JFRA 1QXZA 2MATA 1B59A 1QXYA 4PNCA 2ADUA 1C23A 4U71A 5CNXA 3IU9A 2BN7A 5CLSA 2BWUA 4ZNGA 2NQ6A 4RZZA 3TB5A 1R5HA 4IF7A 4ZWPA 4IPAA 4FO8A 2G6PA 2Q92A 1CHMA 2GU5A 2BWVA 3MX6A 1W7VA 1WKMA 1WL9A 2V3XA 5CE6A 1WL6A 5D6EA 4HXXA 3MATA 2BWTA 3PKBA 2DFIA 4RGZ1 4JUQA 1XGSA 2V3ZA 3CB5A 4KM3A 3S6BA 1XNZA 2EA4A 5CDEA 2GG3A 3BIPA 3RVAA 5E5BA 4IKUA 1XGNA 4U6CA 2P99A 1KQ9A 2V3YA 1O0XA 4S2RP 4MATA 1BN5A 2BWYA 1C21A 4IKTA 2Q8KA 4PV4A 2GZ5A
chains in the Genus database with same CATH topology
4B28A 3BIQA 2GU4A 1Y1NA 4U6JA 3PKEA 1R5GA 2BWWA 2ZSGA 3IU8A 4S01A 1WLRA 4FKCA 2OKNA 5FCFA 3Q6DA 4S00A 1C24A 4U6ZA 4QR8A 5JHUA 1YW7A 2NQ7A 5D6FA 2EVOA 2GU6A 3MR1A 4U75A 3FM3A 4Z7MA 2Q93A 3RORA 2BHAA 4RZYA 3FMRA 1WN1A 4FLJA 4U73A 3BITA 1C22A 3L7GA 4FLIA 4IECA 5FCHA 1QXWA 1C27A 4S2TP 4IKSA 2GG7A 3FMQA 4U6WA 5CDVA 2P98A 2HOWA 4FLLA 2BHBA 1M35A 1KQ0A 3PKAA 1KP0A 4U70A 4IDYA 1YW9A 2BB7A 3CTZA 3L24A 4FUKA 1YJ3A 2GA2A 2BHDA 2GGBA 4FLKA 1N51A 2EA2A 2BWSA 3IG4A 3PKCA 1BOAA 1MATA 1WBQA 3D27A 2GTXA 4U6EA 4IU6A 2EVCA 1R58A 1YW8A 2Q94A 2Q96A 2B3KA 1B6AA 3PKDA 2GGCA 4OOKA 3TAVA 1W2MA 3CB6A 1QZYA 4U76A 1PV9A 2B3LA 5CDLA 2GG8A 5CIKA 2EVMA 1XGOA 2P9AA 4ZWUA 2GG9A 2OAZA 2IW2A 4ZWOA 4FO7A 1JAWA 2GG0A 4EGEA 1YVMA 2Q95A 3IU7A 2BWXA 2B3HA 4A6WA 4A6VA 1XGMA 2BHCA 4U69A 5JI6A 4U1BA 2GG5A 4R60A 1A16A 2BH3A 2GG2A 2GU7A 1WY2A 2V6CA 4IKRA 5JFRA 1QXZA 2MATA 1B59A 1QXYA 4PNCA 2ADUA 1C23A 4U71A 5CNXA 3IU9A 2BN7A 5CLSA 2BWUA 4ZNGA 2NQ6A 4RZZA 3TB5A 1R5HA 4IF7A 4ZWPA 4IPAA 4FO8A 2G6PA 2Q92A 1CHMA 2GU5A 2BWVA 3MX6A 1W7VA 1WKMA 1WL9A 2V3XA 5CE6A 1WL6A 5D6EA 4HXXA 3MATA 2BWTA 3PKBA 2DFIA 4RGZ1 4JUQA 1XGSA 2V3ZA 3CB5A 4KM3A 3S6BA 1XNZA 2EA4A 5CDEA 2GG3A 3BIPA 3RVAA 5E5BA 4IKUA 1XGNA 4U6CA 2P99A 1KQ9A 2V3YA 1O0XA 4S2RP 4MATA 1BN5A 2BWYA 1C21A 4IKTA 2Q8KA 4PV4A 2GZ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B28 A;  3BIQ A;  2GU4 A;  1Y1N A;  4U6J A;  3PKE A;  1R5G A;  2BWW A;  2ZSG A;  3IU8 A;  4S01 A;  1WLR A;  4FKC A;  2OKN A;  5FCF A;  3Q6D A;  4S00 A;  1C24 A;  4U6Z A;  4QR8 A;  5JHU A;  1YW7 A;  2NQ7 A;  5D6F A;  2EVO A;  2GU6 A;  3MR1 A;  4U75 A;  3FM3 A;  4Z7M A;  2Q93 A;  3ROR A;  2BHA A;  4RZY A;  3FMR A;  1WN1 A;  4FLJ A;  4U73 A;  3BIT A;  1C22 A;  3L7G A;  4FLI A;  4IEC A;  5FCH A;  1QXW A;  1C27 A;  4S2T P;  4IKS A;  2GG7 A;  3FMQ A;  4U6W A;  5CDV A;  2P98 A;  2HOW A;  4FLL A;  2BHB A;  1M35 A;  1KQ0 A;  3PKA A;  1KP0 A;  4U70 A;  4IDY A;  1YW9 A;  2BB7 A;  3CTZ A;  3L24 A;  4FUK A;  1YJ3 A;  2GA2 A;  2BHD A;  2GGB A;  4FLK A;  1N51 A;  2EA2 A;  2BWS A;  3IG4 A;  3PKC A;  1BOA A;  1MAT A;  1WBQ A;  3D27 A;  2GTX A;  4U6E A;  4IU6 A;  2EVC A;  1R58 A;  1YW8 A;  2Q94 A;  2Q96 A;  2B3K A;  1B6A A;  3PKD A;  2GGC A;  4OOK A;  3TAV A;  1W2M A;  3CB6 A;  1QZY A;  4U76 A;  1PV9 A;  2B3L A;  5CDL A;  2GG8 A;  5CIK A;  2EVM A;  1XGO A;  2P9A A;  4ZWU A;  2GG9 A;  2OAZ A;  2IW2 A;  4ZWO A;  4FO7 A;  1JAW A;  2GG0 A;  4EGE A;  1YVM A;  2Q95 A;  3IU7 A;  2BWX A;  2B3H A;  4A6W A;  4A6V A;  1XGM A;  2BHC A;  4U69 A;  5JI6 A;  4U1B A;  2GG5 A;  4R60 A;  1A16 A;  2BH3 A;  2GG2 A;  2GU7 A;  1WY2 A;  2V6C A;  4IKR A;  5JFR A;  1QXZ A;  2MAT A;  1B59 A;  1QXY A;  4PNC A;  2ADU A;  1C23 A;  4U71 A;  5CNX A;  3IU9 A;  2BN7 A;  5CLS A;  2BWU A;  4ZNG A;  2NQ6 A;  4RZZ A;  3TB5 A;  1R5H A;  4IF7 A;  4ZWP A;  4IPA A;  4FO8 A;  2G6P A;  2Q92 A;  1CHM A;  2GU5 A;  2BWV A;  3MX6 A;  1W7V A;  1WKM A;  1WL9 A;  2V3X A;  5CE6 A;  1WL6 A;  5D6E A;  4HXX A;  3MAT A;  2BWT A;  3PKB A;  2DFI A;  4RGZ 1;  4JUQ A;  1XGS A;  2V3Z A;  3CB5 A;  4KM3 A;  3S6B A;  1XNZ A;  2EA4 A;  5CDE A;  2GG3 A;  3BIP A;  3RVA A;  5E5B A;  4IKU A;  1XGN A;  4U6C A;  2P99 A;  1KQ9 A;  2V3Y A;  1O0X A;  4S2R P;  4MAT A;  1BN5 A;  2BWY A;  1C21 A;  4IKT A;  2Q8K A;  4PV4 A;  2GZ5 A; 
#chains in the Genus database with same CATH topology
 4B28 A;  3BIQ A;  2GU4 A;  1Y1N A;  4U6J A;  3PKE A;  1R5G A;  2BWW A;  2ZSG A;  3IU8 A;  4S01 A;  1WLR A;  4FKC A;  2OKN A;  5FCF A;  3Q6D A;  4S00 A;  1C24 A;  4U6Z A;  4QR8 A;  5JHU A;  1YW7 A;  2NQ7 A;  5D6F A;  2EVO A;  2GU6 A;  3MR1 A;  4U75 A;  3FM3 A;  4Z7M A;  2Q93 A;  3ROR A;  2BHA A;  4RZY A;  3FMR A;  1WN1 A;  4FLJ A;  4U73 A;  3BIT A;  1C22 A;  3L7G A;  4FLI A;  4IEC A;  5FCH A;  1QXW A;  1C27 A;  4S2T P;  4IKS A;  2GG7 A;  3FMQ A;  4U6W A;  5CDV A;  2P98 A;  2HOW A;  4FLL A;  2BHB A;  1M35 A;  1KQ0 A;  3PKA A;  1KP0 A;  4U70 A;  4IDY A;  1YW9 A;  2BB7 A;  3CTZ A;  3L24 A;  4FUK A;  1YJ3 A;  2GA2 A;  2BHD A;  2GGB A;  4FLK A;  1N51 A;  2EA2 A;  2BWS A;  3IG4 A;  3PKC A;  1BOA A;  1MAT A;  1WBQ A;  3D27 A;  2GTX A;  4U6E A;  4IU6 A;  2EVC A;  1R58 A;  1YW8 A;  2Q94 A;  2Q96 A;  2B3K A;  1B6A A;  3PKD A;  2GGC A;  4OOK A;  3TAV A;  1W2M A;  3CB6 A;  1QZY A;  4U76 A;  1PV9 A;  2B3L A;  5CDL A;  2GG8 A;  5CIK A;  2EVM A;  1XGO A;  2P9A A;  4ZWU A;  2GG9 A;  2OAZ A;  2IW2 A;  4ZWO A;  4FO7 A;  1JAW A;  2GG0 A;  4EGE A;  1YVM A;  2Q95 A;  3IU7 A;  2BWX A;  2B3H A;  4A6W A;  4A6V A;  1XGM A;  2BHC A;  4U69 A;  5JI6 A;  4U1B A;  2GG5 A;  4R60 A;  1A16 A;  2BH3 A;  2GG2 A;  2GU7 A;  1WY2 A;  2V6C A;  4IKR A;  5JFR A;  1QXZ A;  2MAT A;  1B59 A;  1QXY A;  4PNC A;  2ADU A;  1C23 A;  4U71 A;  5CNX A;  3IU9 A;  2BN7 A;  5CLS A;  2BWU A;  4ZNG A;  2NQ6 A;  4RZZ A;  3TB5 A;  1R5H A;  4IF7 A;  4ZWP A;  4IPA A;  4FO8 A;  2G6P A;  2Q92 A;  1CHM A;  2GU5 A;  2BWV A;  3MX6 A;  1W7V A;  1WKM A;  1WL9 A;  2V3X A;  5CE6 A;  1WL6 A;  5D6E A;  4HXX A;  3MAT A;  2BWT A;  3PKB A;  2DFI A;  4RGZ 1;  4JUQ A;  1XGS A;  2V3Z A;  3CB5 A;  4KM3 A;  3S6B A;  1XNZ A;  2EA4 A;  5CDE A;  2GG3 A;  3BIP A;  3RVA A;  5E5B A;  4IKU A;  1XGN A;  4U6C A;  2P99 A;  1KQ9 A;  2V3Y A;  1O0X A;  4S2R P;  4MAT A;  1BN5 A;  2BWY A;  1C21 A;  4IKT A;  2Q8K A;  4PV4 A;  2GZ5 A; 
#chains in the Genus database with same CATH homology
 4B28 A;  3BIQ A;  2GU4 A;  1Y1N A;  4U6J A;  3PKE A;  1R5G A;  2BWW A;  2ZSG A;  3IU8 A;  4S01 A;  1WLR A;  4FKC A;  2OKN A;  5FCF A;  3Q6D A;  4S00 A;  1C24 A;  4U6Z A;  4QR8 A;  5JHU A;  1YW7 A;  2NQ7 A;  5D6F A;  2EVO A;  2GU6 A;  3MR1 A;  4U75 A;  3FM3 A;  4Z7M A;  2Q93 A;  3ROR A;  2BHA A;  4RZY A;  3FMR A;  1WN1 A;  4FLJ A;  4U73 A;  3BIT A;  1C22 A;  3L7G A;  4FLI A;  4IEC A;  5FCH A;  1QXW A;  1C27 A;  4S2T P;  4IKS A;  2GG7 A;  3FMQ A;  4U6W A;  5CDV A;  2P98 A;  2HOW A;  4FLL A;  2BHB A;  1M35 A;  1KQ0 A;  3PKA A;  1KP0 A;  4U70 A;  4IDY A;  1YW9 A;  2BB7 A;  3CTZ A;  3L24 A;  4FUK A;  1YJ3 A;  2GA2 A;  2BHD A;  2GGB A;  4FLK A;  1N51 A;  2EA2 A;  2BWS A;  3IG4 A;  3PKC A;  1BOA A;  1MAT A;  1WBQ A;  3D27 A;  2GTX A;  4U6E A;  4IU6 A;  2EVC A;  1R58 A;  1YW8 A;  2Q94 A;  2Q96 A;  2B3K A;  1B6A A;  3PKD A;  2GGC A;  4OOK A;  3TAV A;  1W2M A;  3CB6 A;  1QZY A;  4U76 A;  1PV9 A;  2B3L A;  5CDL A;  2GG8 A;  5CIK A;  2EVM A;  1XGO A;  2P9A A;  4ZWU A;  2GG9 A;  2OAZ A;  2IW2 A;  4ZWO A;  4FO7 A;  1JAW A;  2GG0 A;  4EGE A;  1YVM A;  2Q95 A;  3IU7 A;  2BWX A;  2B3H A;  4A6W A;  4A6V A;  1XGM A;  2BHC A;  4U69 A;  5JI6 A;  4U1B A;  2GG5 A;  4R60 A;  1A16 A;  2BH3 A;  2GG2 A;  2GU7 A;  1WY2 A;  2V6C A;  4IKR A;  5JFR A;  1QXZ A;  2MAT A;  1B59 A;  1QXY A;  4PNC A;  2ADU A;  1C23 A;  4U71 A;  5CNX A;  3IU9 A;  2BN7 A;  5CLS A;  2BWU A;  4ZNG A;  2NQ6 A;  4RZZ A;  3TB5 A;  1R5H A;  4IF7 A;  4ZWP A;  4IPA A;  4FO8 A;  2G6P A;  2Q92 A;  1CHM A;  2GU5 A;  2BWV A;  3MX6 A;  1W7V A;  1WKM A;  1WL9 A;  2V3X A;  5CE6 A;  1WL6 A;  5D6E A;  4HXX A;  3MAT A;  2BWT A;  3PKB A;  2DFI A;  4RGZ 1;  4JUQ A;  1XGS A;  2V3Z A;  3CB5 A;  4KM3 A;  3S6B A;  1XNZ A;  2EA4 A;  5CDE A;  2GG3 A;  3BIP A;  3RVA A;  5E5B A;  4IKU A;  1XGN A;  4U6C A;  2P99 A;  1KQ9 A;  2V3Y A;  1O0X A;  4S2R P;  4MAT A;  1BN5 A;  2BWY A;  1C21 A;  4IKT A;  2Q8K A;  4PV4 A;  2GZ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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