2GU7A

E. coli methionine aminopeptidase unliganded, 1:0.5
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
261
structure length
261
Chain Sequence
SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural basis of catalysis by monometalated methionine aminopeptidase.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Escherichia coli
total genus 80
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2gu7A00
3CTZA 3PKBA 2GU7A 3BIQA 4U69A 4A6WA 2P9AA 1A16A 4FLKA 5FCHA 1B6AA 1XGNA 1B59A 4FLLA 5JFRA 3Q6DA 2GGBA 1BN5A 4QR8A 4IDYA 1R58A 1KQ9A 1WL6A 1WY2A 1R5HA 4A6VA 1BOAA 4IF7A 2BWYA 1KP0A 2BWTA 3PKCA 4IKTA 4IPAA 5CDEA 1W7VA 4U6JA 1MATA 4FKCA 2GG8A 1R5GA 2OKNA 2G6PA 3RVAA 2V6CA 5E5BA 1O0XA 5CDVA 2BHBA 2ADUA 1QXWA 1QZYA 2P98A 3FMQA 4IU6A 5FCFA 2BB7A 4S2RP 2GG0A 1YW9A 2ZSGA 2GA2A 2GG2A 4FLIA 4ZWPA 4FO7A 3MR1A 2GG5A 1QXZA 4U6EA 3BITA 4IKRA 4U75A 4HXXA 1WL9A 2BWSA 4FUKA 3CB5A 2Q96A 4U6WA 4U1BA 2GG9A 4RZYA 3L7GA 3FMRA 4U70A 4U6CA 3RORA 2GG7A 5CNXA 2BHCA 2BWXA 4U6ZA 2BHDA 3TAVA 3IU9A 2V3ZA 1C23A 4PNCA 2GU6A 5CE6A 2BWUA 2DFIA 5CLSA 4JUQA 3IG4A 1YW8A 5CIKA 1M35A 1WBQA 1XGOA 1C27A 1QXYA 4FLJA 1C22A 4S2TP 2Q93A 2IW2A 3MX6A 4FO8A 2GU5A 1YJ3A 2MATA 3BIPA 4IECA 2EA2A 2GG3A 1WLRA 3PKAA 2EVCA 3D27A 5D6EA 2GTXA 4U76A 1KQ0A 4S00A 4ZNGA 4ZWOA 2GU4A 2B3KA 2GZ5A 4IKUA 2B3HA 1XGSA 4KM3A 4R60A 4U73A 4EGEA 2BN7A 2GGCA 3IU8A 1JAWA 2V3XA 1C24A 3CB6A 2BHAA 2Q95A 2NQ7A 2B3LA 3MATA 5D6FA 2Q8KA 4B28A 5JHUA 1N51A 1WN1A 2BWWA 2Q94A 1PV9A 2P99A 1C21A 4U71A 5JI6A 2EVOA 2BH3A 1YW7A 3PKEA 3TB5A 4Z7MA 4RGZ1 4RZZA 4ZWUA 4IKSA 1CHMA 1YVMA 2EVMA 4MATA 4PV4A 3S6BA 1W2MA 5CDLA 1WKMA 2Q92A 2EA4A 1XNZA 3FM3A 3L24A 4S01A 2V3YA 3PKDA 1XGMA 2OAZA 1Y1NA 2HOWA 4OOKA 3IU7A 2NQ6A 2BWVA
chains in the Genus database with same CATH superfamily
3CTZA 3PKBA 2GU7A 3BIQA 4U69A 4A6WA 2P9AA 1A16A 4FLKA 5FCHA 1B6AA 1XGNA 1B59A 4FLLA 5JFRA 3Q6DA 2GGBA 1BN5A 4QR8A 4IDYA 1R58A 1KQ9A 1WL6A 1WY2A 1R5HA 4A6VA 1BOAA 4IF7A 2BWYA 1KP0A 2BWTA 3PKCA 4IKTA 4IPAA 5CDEA 1W7VA 4U6JA 1MATA 4FKCA 2GG8A 1R5GA 2OKNA 2G6PA 3RVAA 2V6CA 5E5BA 1O0XA 5CDVA 2BHBA 2ADUA 1QXWA 1QZYA 2P98A 3FMQA 4IU6A 5FCFA 2BB7A 4S2RP 2GG0A 1YW9A 2ZSGA 2GA2A 2GG2A 4FLIA 4ZWPA 4FO7A 3MR1A 2GG5A 1QXZA 4U6EA 3BITA 4IKRA 4U75A 4HXXA 1WL9A 2BWSA 4FUKA 3CB5A 2Q96A 4U6WA 4U1BA 2GG9A 4RZYA 3L7GA 3FMRA 4U70A 4U6CA 3RORA 2GG7A 5CNXA 2BHCA 2BWXA 4U6ZA 2BHDA 3TAVA 3IU9A 2V3ZA 1C23A 4PNCA 2GU6A 5CE6A 2BWUA 2DFIA 5CLSA 4JUQA 3IG4A 1YW8A 5CIKA 1M35A 1WBQA 1XGOA 1C27A 1QXYA 4FLJA 1C22A 4S2TP 2Q93A 2IW2A 3MX6A 4FO8A 2GU5A 1YJ3A 2MATA 3BIPA 4IECA 2EA2A 2GG3A 1WLRA 3PKAA 2EVCA 3D27A 5D6EA 2GTXA 4U76A 1KQ0A 4S00A 4ZNGA 4ZWOA 2GU4A 2B3KA 2GZ5A 4IKUA 2B3HA 1XGSA 4KM3A 4R60A 4U73A 4EGEA 2BN7A 2GGCA 3IU8A 1JAWA 2V3XA 1C24A 3CB6A 2BHAA 2Q95A 2NQ7A 2B3LA 3MATA 5D6FA 2Q8KA 4B28A 5JHUA 1N51A 1WN1A 2BWWA 2Q94A 1PV9A 2P99A 1C21A 4U71A 5JI6A 2EVOA 2BH3A 1YW7A 3PKEA 3TB5A 4Z7MA 4RGZ1 4RZZA 4ZWUA 4IKSA 1CHMA 1YVMA 2EVMA 4MATA 4PV4A 3S6BA 1W2MA 5CDLA 1WKMA 2Q92A 2EA4A 1XNZA 3FM3A 3L24A 4S01A 2V3YA 3PKDA 1XGMA 2OAZA 1Y1NA 2HOWA 4OOKA 3IU7A 2NQ6A 2BWVA
chains in the Genus database with same CATH topology
3CTZA 3PKBA 2GU7A 3BIQA 4U69A 4A6WA 2P9AA 1A16A 4FLKA 5FCHA 1B6AA 1XGNA 1B59A 4FLLA 5JFRA 3Q6DA 2GGBA 1BN5A 4QR8A 4IDYA 1R58A 1KQ9A 1WL6A 1WY2A 1R5HA 4A6VA 1BOAA 4IF7A 2BWYA 1KP0A 2BWTA 3PKCA 4IKTA 4IPAA 5CDEA 1W7VA 4U6JA 1MATA 4FKCA 2GG8A 1R5GA 2OKNA 2G6PA 3RVAA 2V6CA 5E5BA 1O0XA 5CDVA 2BHBA 2ADUA 1QXWA 1QZYA 2P98A 3FMQA 4IU6A 5FCFA 2BB7A 4S2RP 2GG0A 1YW9A 2ZSGA 2GA2A 2GG2A 4FLIA 4ZWPA 4FO7A 3MR1A 2GG5A 1QXZA 4U6EA 3BITA 4IKRA 4U75A 4HXXA 1WL9A 2BWSA 4FUKA 3CB5A 2Q96A 4U6WA 4U1BA 2GG9A 4RZYA 3L7GA 3FMRA 4U70A 4U6CA 3RORA 2GG7A 5CNXA 2BHCA 2BWXA 4U6ZA 2BHDA 3TAVA 3IU9A 2V3ZA 1C23A 4PNCA 2GU6A 5CE6A 2BWUA 2DFIA 5CLSA 4JUQA 3IG4A 1YW8A 5CIKA 1M35A 1WBQA 1XGOA 1C27A 1QXYA 4FLJA 1C22A 4S2TP 2Q93A 2IW2A 3MX6A 4FO8A 2GU5A 1YJ3A 2MATA 3BIPA 4IECA 2EA2A 2GG3A 1WLRA 3PKAA 2EVCA 3D27A 5D6EA 2GTXA 4U76A 1KQ0A 4S00A 4ZNGA 4ZWOA 2GU4A 2B3KA 2GZ5A 4IKUA 2B3HA 1XGSA 4KM3A 4R60A 4U73A 4EGEA 2BN7A 2GGCA 3IU8A 1JAWA 2V3XA 1C24A 3CB6A 2BHAA 2Q95A 2NQ7A 2B3LA 3MATA 5D6FA 2Q8KA 4B28A 5JHUA 1N51A 1WN1A 2BWWA 2Q94A 1PV9A 2P99A 1C21A 4U71A 5JI6A 2EVOA 2BH3A 1YW7A 3PKEA 3TB5A 4Z7MA 4RGZ1 4RZZA 4ZWUA 4IKSA 1CHMA 1YVMA 2EVMA 4MATA 4PV4A 3S6BA 1W2MA 5CDLA 1WKMA 2Q92A 2EA4A 1XNZA 3FM3A 3L24A 4S01A 2V3YA 3PKDA 1XGMA 2OAZA 1Y1NA 2HOWA 4OOKA 3IU7A 2NQ6A 2BWVA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3CTZ A;  3PKB A;  2GU7 A;  3BIQ A;  4U69 A;  4A6W A;  2P9A A;  1A16 A;  4FLK A;  5FCH A;  1B6A A;  1XGN A;  1B59 A;  4FLL A;  5JFR A;  3Q6D A;  2GGB A;  1BN5 A;  4QR8 A;  4IDY A;  1R58 A;  1KQ9 A;  1WL6 A;  1WY2 A;  1R5H A;  4A6V A;  1BOA A;  4IF7 A;  2BWY A;  1KP0 A;  2BWT A;  3PKC A;  4IKT A;  4IPA A;  5CDE A;  1W7V A;  4U6J A;  1MAT A;  4FKC A;  2GG8 A;  1R5G A;  2OKN A;  2G6P A;  3RVA A;  2V6C A;  5E5B A;  1O0X A;  5CDV A;  2BHB A;  2ADU A;  1QXW A;  1QZY A;  2P98 A;  3FMQ A;  4IU6 A;  5FCF A;  2BB7 A;  4S2R P;  2GG0 A;  1YW9 A;  2ZSG A;  2GA2 A;  2GG2 A;  4FLI A;  4ZWP A;  4FO7 A;  3MR1 A;  2GG5 A;  1QXZ A;  4U6E A;  3BIT A;  4IKR A;  4U75 A;  4HXX A;  1WL9 A;  2BWS A;  4FUK A;  3CB5 A;  2Q96 A;  4U6W A;  4U1B A;  2GG9 A;  4RZY A;  3L7G A;  3FMR A;  4U70 A;  4U6C A;  3ROR A;  2GG7 A;  5CNX A;  2BHC A;  2BWX A;  4U6Z A;  2BHD A;  3TAV A;  3IU9 A;  2V3Z A;  1C23 A;  4PNC A;  2GU6 A;  5CE6 A;  2BWU A;  2DFI A;  5CLS A;  4JUQ A;  3IG4 A;  1YW8 A;  5CIK A;  1M35 A;  1WBQ A;  1XGO A;  1C27 A;  1QXY A;  4FLJ A;  1C22 A;  4S2T P;  2Q93 A;  2IW2 A;  3MX6 A;  4FO8 A;  2GU5 A;  1YJ3 A;  2MAT A;  3BIP A;  4IEC A;  2EA2 A;  2GG3 A;  1WLR A;  3PKA A;  2EVC A;  3D27 A;  5D6E A;  2GTX A;  4U76 A;  1KQ0 A;  4S00 A;  4ZNG A;  4ZWO A;  2GU4 A;  2B3K A;  2GZ5 A;  4IKU A;  2B3H A;  1XGS A;  4KM3 A;  4R60 A;  4U73 A;  4EGE A;  2BN7 A;  2GGC A;  3IU8 A;  1JAW A;  2V3X A;  1C24 A;  3CB6 A;  2BHA A;  2Q95 A;  2NQ7 A;  2B3L A;  3MAT A;  5D6F A;  2Q8K A;  4B28 A;  5JHU A;  1N51 A;  1WN1 A;  2BWW A;  2Q94 A;  1PV9 A;  2P99 A;  1C21 A;  4U71 A;  5JI6 A;  2EVO A;  2BH3 A;  1YW7 A;  3PKE A;  3TB5 A;  4Z7M A;  4RGZ 1;  4RZZ A;  4ZWU A;  4IKS A;  1CHM A;  1YVM A;  2EVM A;  4MAT A;  4PV4 A;  3S6B A;  1W2M A;  5CDL A;  1WKM A;  2Q92 A;  2EA4 A;  1XNZ A;  3FM3 A;  3L24 A;  4S01 A;  2V3Y A;  3PKD A;  1XGM A;  2OAZ A;  1Y1N A;  2HOW A;  4OOK A;  3IU7 A;  2NQ6 A;  2BWV A; 
#chains in the Genus database with same CATH topology
 3CTZ A;  3PKB A;  2GU7 A;  3BIQ A;  4U69 A;  4A6W A;  2P9A A;  1A16 A;  4FLK A;  5FCH A;  1B6A A;  1XGN A;  1B59 A;  4FLL A;  5JFR A;  3Q6D A;  2GGB A;  1BN5 A;  4QR8 A;  4IDY A;  1R58 A;  1KQ9 A;  1WL6 A;  1WY2 A;  1R5H A;  4A6V A;  1BOA A;  4IF7 A;  2BWY A;  1KP0 A;  2BWT A;  3PKC A;  4IKT A;  4IPA A;  5CDE A;  1W7V A;  4U6J A;  1MAT A;  4FKC A;  2GG8 A;  1R5G A;  2OKN A;  2G6P A;  3RVA A;  2V6C A;  5E5B A;  1O0X A;  5CDV A;  2BHB A;  2ADU A;  1QXW A;  1QZY A;  2P98 A;  3FMQ A;  4IU6 A;  5FCF A;  2BB7 A;  4S2R P;  2GG0 A;  1YW9 A;  2ZSG A;  2GA2 A;  2GG2 A;  4FLI A;  4ZWP A;  4FO7 A;  3MR1 A;  2GG5 A;  1QXZ A;  4U6E A;  3BIT A;  4IKR A;  4U75 A;  4HXX A;  1WL9 A;  2BWS A;  4FUK A;  3CB5 A;  2Q96 A;  4U6W A;  4U1B A;  2GG9 A;  4RZY A;  3L7G A;  3FMR A;  4U70 A;  4U6C A;  3ROR A;  2GG7 A;  5CNX A;  2BHC A;  2BWX A;  4U6Z A;  2BHD A;  3TAV A;  3IU9 A;  2V3Z A;  1C23 A;  4PNC A;  2GU6 A;  5CE6 A;  2BWU A;  2DFI A;  5CLS A;  4JUQ A;  3IG4 A;  1YW8 A;  5CIK A;  1M35 A;  1WBQ A;  1XGO A;  1C27 A;  1QXY A;  4FLJ A;  1C22 A;  4S2T P;  2Q93 A;  2IW2 A;  3MX6 A;  4FO8 A;  2GU5 A;  1YJ3 A;  2MAT A;  3BIP A;  4IEC A;  2EA2 A;  2GG3 A;  1WLR A;  3PKA A;  2EVC A;  3D27 A;  5D6E A;  2GTX A;  4U76 A;  1KQ0 A;  4S00 A;  4ZNG A;  4ZWO A;  2GU4 A;  2B3K A;  2GZ5 A;  4IKU A;  2B3H A;  1XGS A;  4KM3 A;  4R60 A;  4U73 A;  4EGE A;  2BN7 A;  2GGC A;  3IU8 A;  1JAW A;  2V3X A;  1C24 A;  3CB6 A;  2BHA A;  2Q95 A;  2NQ7 A;  2B3L A;  3MAT A;  5D6F A;  2Q8K A;  4B28 A;  5JHU A;  1N51 A;  1WN1 A;  2BWW A;  2Q94 A;  1PV9 A;  2P99 A;  1C21 A;  4U71 A;  5JI6 A;  2EVO A;  2BH3 A;  1YW7 A;  3PKE A;  3TB5 A;  4Z7M A;  4RGZ 1;  4RZZ A;  4ZWU A;  4IKS A;  1CHM A;  1YVM A;  2EVM A;  4MAT A;  4PV4 A;  3S6B A;  1W2M A;  5CDL A;  1WKM A;  2Q92 A;  2EA4 A;  1XNZ A;  3FM3 A;  3L24 A;  4S01 A;  2V3Y A;  3PKD A;  1XGM A;  2OAZ A;  1Y1N A;  2HOW A;  4OOK A;  3IU7 A;  2NQ6 A;  2BWV A; 
#chains in the Genus database with same CATH homology
 3CTZ A;  3PKB A;  2GU7 A;  3BIQ A;  4U69 A;  4A6W A;  2P9A A;  1A16 A;  4FLK A;  5FCH A;  1B6A A;  1XGN A;  1B59 A;  4FLL A;  5JFR A;  3Q6D A;  2GGB A;  1BN5 A;  4QR8 A;  4IDY A;  1R58 A;  1KQ9 A;  1WL6 A;  1WY2 A;  1R5H A;  4A6V A;  1BOA A;  4IF7 A;  2BWY A;  1KP0 A;  2BWT A;  3PKC A;  4IKT A;  4IPA A;  5CDE A;  1W7V A;  4U6J A;  1MAT A;  4FKC A;  2GG8 A;  1R5G A;  2OKN A;  2G6P A;  3RVA A;  2V6C A;  5E5B A;  1O0X A;  5CDV A;  2BHB A;  2ADU A;  1QXW A;  1QZY A;  2P98 A;  3FMQ A;  4IU6 A;  5FCF A;  2BB7 A;  4S2R P;  2GG0 A;  1YW9 A;  2ZSG A;  2GA2 A;  2GG2 A;  4FLI A;  4ZWP A;  4FO7 A;  3MR1 A;  2GG5 A;  1QXZ A;  4U6E A;  3BIT A;  4IKR A;  4U75 A;  4HXX A;  1WL9 A;  2BWS A;  4FUK A;  3CB5 A;  2Q96 A;  4U6W A;  4U1B A;  2GG9 A;  4RZY A;  3L7G A;  3FMR A;  4U70 A;  4U6C A;  3ROR A;  2GG7 A;  5CNX A;  2BHC A;  2BWX A;  4U6Z A;  2BHD A;  3TAV A;  3IU9 A;  2V3Z A;  1C23 A;  4PNC A;  2GU6 A;  5CE6 A;  2BWU A;  2DFI A;  5CLS A;  4JUQ A;  3IG4 A;  1YW8 A;  5CIK A;  1M35 A;  1WBQ A;  1XGO A;  1C27 A;  1QXY A;  4FLJ A;  1C22 A;  4S2T P;  2Q93 A;  2IW2 A;  3MX6 A;  4FO8 A;  2GU5 A;  1YJ3 A;  2MAT A;  3BIP A;  4IEC A;  2EA2 A;  2GG3 A;  1WLR A;  3PKA A;  2EVC A;  3D27 A;  5D6E A;  2GTX A;  4U76 A;  1KQ0 A;  4S00 A;  4ZNG A;  4ZWO A;  2GU4 A;  2B3K A;  2GZ5 A;  4IKU A;  2B3H A;  1XGS A;  4KM3 A;  4R60 A;  4U73 A;  4EGE A;  2BN7 A;  2GGC A;  3IU8 A;  1JAW A;  2V3X A;  1C24 A;  3CB6 A;  2BHA A;  2Q95 A;  2NQ7 A;  2B3L A;  3MAT A;  5D6F A;  2Q8K A;  4B28 A;  5JHU A;  1N51 A;  1WN1 A;  2BWW A;  2Q94 A;  1PV9 A;  2P99 A;  1C21 A;  4U71 A;  5JI6 A;  2EVO A;  2BH3 A;  1YW7 A;  3PKE A;  3TB5 A;  4Z7M A;  4RGZ 1;  4RZZ A;  4ZWU A;  4IKS A;  1CHM A;  1YVM A;  2EVM A;  4MAT A;  4PV4 A;  3S6B A;  1W2M A;  5CDL A;  1WKM A;  2Q92 A;  2EA4 A;  1XNZ A;  3FM3 A;  3L24 A;  4S01 A;  2V3Y A;  3PKD A;  1XGM A;  2OAZ A;  1Y1N A;  2HOW A;  4OOK A;  3IU7 A;  2NQ6 A;  2BWV A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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