2GU7A

E. coli methionine aminopeptidase unliganded, 1:0.5
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
261
structure length
261
Chain Sequence
SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural basis of catalysis by monometalated methionine aminopeptidase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Methionine aminopeptidase
total genus 80
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2gu7A00
2BWUA 2V3XA 2BWXA 4U6EA 4FO8A 1BN5A 1W2MA 1C23A 2BHBA 2BWTA 1CHMA 2GTXA 4R60A 4U71A 4IPAA 4ZWUA 3L24A 2V6CA 2DFIA 4U70A 1YW9A 1YVMA 5CDVA 2P98A 4FLLA 5CDEA 5CDLA 2IW2A 4B28A 1C21A 4RGZ1 1W7VA 1KP0A 3MATA 4IKSA 1C27A 3L7GA 4U6JA 2EVOA 2OAZA 3PKBA 3CB6A 3MR1A 3RORA 2BWWA 4IKRA 1WLRA 2Q96A 1C22A 3CB5A 1B6AA 1M35A 2MATA 5JI6A 1C24A 3IU9A 5JFRA 3BIQA 2GU5A 2Q95A 1WBQA 1MATA 4ZWOA 4PV4A 2EA2A 3TB5A 1XGSA 2GGBA 4ZNGA 4IU6A 1QZYA 2GU7A 1BOAA 5JHUA 1WL9A 1YW7A 4U76A 1XGNA 2Q8KA 2BHDA 4A6VA 4FLKA 4IKTA 1R58A 2GG8A 1KQ0A 2BWYA 2NQ7A 2V3YA 4IF7A 2P9AA 2NQ6A 1XGMA 4IECA 4FLIA 4HXXA 1O0XA 5CLSA 2Q94A 1R5GA 3S6BA 5FCHA 3PKEA 2BHAA 2GG0A 1WY2A 2HOWA 3MX6A 1PV9A 4U6CA 1B59A 2GG3A 2GG5A 2GG2A 2Q93A 5CE6A 1QXZA 2GG9A 4U69A 1XGOA 3TAVA 1R5HA 1JAWA 4S00A 2B3LA 4OOKA 2B3KA 3PKCA 4FUKA 3CTZA 4U75A 2GA2A 4EGEA 1WL6A 5E5BA 4FLJA 3D27A 3IU7A 1A16A 5D6FA 4S2TP 2BN7A 4U6WA 4FKCA 2BHCA 3FMRA 2EVCA 3BITA 1KQ9A 5FCFA 1YW8A 4U73A 1N51A 4JUQA 3Q6DA 4U1BA 4QR8A 4RZYA 1QXWA 2V3ZA 1XNZA 2BWSA 4MATA 4IKUA 2ADUA 4Z7MA 2B3HA 3IU8A 2P99A 1YJ3A 4RZZA 2EA4A 3FM3A 4U6ZA 3BIPA 2GZ5A 3IG4A 2ZSGA 2GU4A 2EVMA 2GGCA 4IDYA 3RVAA 2G6PA 5D6EA 4ZWPA 3FMQA 1Y1NA 3PKDA 1WN1A 4PNCA 3PKAA 1WKMA 2BB7A 4FO7A 5CNXA 2BWVA 4KM3A 4S01A 2BH3A 4A6WA 2OKNA 1QXYA 2GG7A 4S2RP 5CIKA 2GU6A 2Q92A
chains in the Genus database with same CATH superfamily
2BWUA 2V3XA 2BWXA 4U6EA 4FO8A 1BN5A 1W2MA 1C23A 2BHBA 2BWTA 1CHMA 2GTXA 4R60A 4U71A 4IPAA 4ZWUA 3L24A 2V6CA 2DFIA 4U70A 1YW9A 1YVMA 5CDVA 2P98A 4FLLA 5CDEA 5CDLA 2IW2A 4B28A 1C21A 4RGZ1 1W7VA 1KP0A 3MATA 4IKSA 1C27A 3L7GA 4U6JA 2EVOA 2OAZA 3PKBA 3CB6A 3MR1A 3RORA 2BWWA 4IKRA 1WLRA 2Q96A 1C22A 3CB5A 1B6AA 1M35A 2MATA 5JI6A 1C24A 3IU9A 5JFRA 3BIQA 2GU5A 2Q95A 1WBQA 1MATA 4ZWOA 4PV4A 2EA2A 3TB5A 1XGSA 2GGBA 4ZNGA 4IU6A 1QZYA 2GU7A 1BOAA 5JHUA 1WL9A 1YW7A 4U76A 1XGNA 2Q8KA 2BHDA 4A6VA 4FLKA 4IKTA 1R58A 2GG8A 1KQ0A 2BWYA 2NQ7A 2V3YA 4IF7A 2P9AA 2NQ6A 1XGMA 4IECA 4FLIA 4HXXA 1O0XA 5CLSA 2Q94A 1R5GA 3S6BA 5FCHA 3PKEA 2BHAA 2GG0A 1WY2A 2HOWA 3MX6A 1PV9A 4U6CA 1B59A 2GG3A 2GG5A 2GG2A 2Q93A 5CE6A 1QXZA 2GG9A 4U69A 1XGOA 3TAVA 1R5HA 1JAWA 4S00A 2B3LA 4OOKA 2B3KA 3PKCA 4FUKA 3CTZA 4U75A 2GA2A 4EGEA 1WL6A 5E5BA 4FLJA 3D27A 3IU7A 1A16A 5D6FA 4S2TP 2BN7A 4U6WA 4FKCA 2BHCA 3FMRA 2EVCA 3BITA 1KQ9A 5FCFA 1YW8A 4U73A 1N51A 4JUQA 3Q6DA 4U1BA 4QR8A 4RZYA 1QXWA 2V3ZA 1XNZA 2BWSA 4MATA 4IKUA 2ADUA 4Z7MA 2B3HA 3IU8A 2P99A 1YJ3A 4RZZA 2EA4A 3FM3A 4U6ZA 3BIPA 2GZ5A 3IG4A 2ZSGA 2GU4A 2EVMA 2GGCA 4IDYA 3RVAA 2G6PA 5D6EA 4ZWPA 3FMQA 1Y1NA 3PKDA 1WN1A 4PNCA 3PKAA 1WKMA 2BB7A 4FO7A 5CNXA 2BWVA 4KM3A 4S01A 2BH3A 4A6WA 2OKNA 1QXYA 2GG7A 4S2RP 5CIKA 2GU6A 2Q92A
chains in the Genus database with same CATH topology
2BWUA 2V3XA 2BWXA 4U6EA 4FO8A 1BN5A 1W2MA 1C23A 2BHBA 2BWTA 1CHMA 2GTXA 4R60A 4U71A 4IPAA 4ZWUA 3L24A 2V6CA 2DFIA 4U70A 1YW9A 1YVMA 5CDVA 2P98A 4FLLA 5CDEA 5CDLA 2IW2A 4B28A 1C21A 4RGZ1 1W7VA 1KP0A 3MATA 4IKSA 1C27A 3L7GA 4U6JA 2EVOA 2OAZA 3PKBA 3CB6A 3MR1A 3RORA 2BWWA 4IKRA 1WLRA 2Q96A 1C22A 3CB5A 1B6AA 1M35A 2MATA 5JI6A 1C24A 3IU9A 5JFRA 3BIQA 2GU5A 2Q95A 1WBQA 1MATA 4ZWOA 4PV4A 2EA2A 3TB5A 1XGSA 2GGBA 4ZNGA 4IU6A 1QZYA 2GU7A 1BOAA 5JHUA 1WL9A 1YW7A 4U76A 1XGNA 2Q8KA 2BHDA 4A6VA 4FLKA 4IKTA 1R58A 2GG8A 1KQ0A 2BWYA 2NQ7A 2V3YA 4IF7A 2P9AA 2NQ6A 1XGMA 4IECA 4FLIA 4HXXA 1O0XA 5CLSA 2Q94A 1R5GA 3S6BA 5FCHA 3PKEA 2BHAA 2GG0A 1WY2A 2HOWA 3MX6A 1PV9A 4U6CA 1B59A 2GG3A 2GG5A 2GG2A 2Q93A 5CE6A 1QXZA 2GG9A 4U69A 1XGOA 3TAVA 1R5HA 1JAWA 4S00A 2B3LA 4OOKA 2B3KA 3PKCA 4FUKA 3CTZA 4U75A 2GA2A 4EGEA 1WL6A 5E5BA 4FLJA 3D27A 3IU7A 1A16A 5D6FA 4S2TP 2BN7A 4U6WA 4FKCA 2BHCA 3FMRA 2EVCA 3BITA 1KQ9A 5FCFA 1YW8A 4U73A 1N51A 4JUQA 3Q6DA 4U1BA 4QR8A 4RZYA 1QXWA 2V3ZA 1XNZA 2BWSA 4MATA 4IKUA 2ADUA 4Z7MA 2B3HA 3IU8A 2P99A 1YJ3A 4RZZA 2EA4A 3FM3A 4U6ZA 3BIPA 2GZ5A 3IG4A 2ZSGA 2GU4A 2EVMA 2GGCA 4IDYA 3RVAA 2G6PA 5D6EA 4ZWPA 3FMQA 1Y1NA 3PKDA 1WN1A 4PNCA 3PKAA 1WKMA 2BB7A 4FO7A 5CNXA 2BWVA 4KM3A 4S01A 2BH3A 4A6WA 2OKNA 1QXYA 2GG7A 4S2RP 5CIKA 2GU6A 2Q92A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2BWU A;  2V3X A;  2BWX A;  4U6E A;  4FO8 A;  1BN5 A;  1W2M A;  1C23 A;  2BHB A;  2BWT A;  1CHM A;  2GTX A;  4R60 A;  4U71 A;  4IPA A;  4ZWU A;  3L24 A;  2V6C A;  2DFI A;  4U70 A;  1YW9 A;  1YVM A;  5CDV A;  2P98 A;  4FLL A;  5CDE A;  5CDL A;  2IW2 A;  4B28 A;  1C21 A;  4RGZ 1;  1W7V A;  1KP0 A;  3MAT A;  4IKS A;  1C27 A;  3L7G A;  4U6J A;  2EVO A;  2OAZ A;  3PKB A;  3CB6 A;  3MR1 A;  3ROR A;  2BWW A;  4IKR A;  1WLR A;  2Q96 A;  1C22 A;  3CB5 A;  1B6A A;  1M35 A;  2MAT A;  5JI6 A;  1C24 A;  3IU9 A;  5JFR A;  3BIQ A;  2GU5 A;  2Q95 A;  1WBQ A;  1MAT A;  4ZWO A;  4PV4 A;  2EA2 A;  3TB5 A;  1XGS A;  2GGB A;  4ZNG A;  4IU6 A;  1QZY A;  2GU7 A;  1BOA A;  5JHU A;  1WL9 A;  1YW7 A;  4U76 A;  1XGN A;  2Q8K A;  2BHD A;  4A6V A;  4FLK A;  4IKT A;  1R58 A;  2GG8 A;  1KQ0 A;  2BWY A;  2NQ7 A;  2V3Y A;  4IF7 A;  2P9A A;  2NQ6 A;  1XGM A;  4IEC A;  4FLI A;  4HXX A;  1O0X A;  5CLS A;  2Q94 A;  1R5G A;  3S6B A;  5FCH A;  3PKE A;  2BHA A;  2GG0 A;  1WY2 A;  2HOW A;  3MX6 A;  1PV9 A;  4U6C A;  1B59 A;  2GG3 A;  2GG5 A;  2GG2 A;  2Q93 A;  5CE6 A;  1QXZ A;  2GG9 A;  4U69 A;  1XGO A;  3TAV A;  1R5H A;  1JAW A;  4S00 A;  2B3L A;  4OOK A;  2B3K A;  3PKC A;  4FUK A;  3CTZ A;  4U75 A;  2GA2 A;  4EGE A;  1WL6 A;  5E5B A;  4FLJ A;  3D27 A;  3IU7 A;  1A16 A;  5D6F A;  4S2T P;  2BN7 A;  4U6W A;  4FKC A;  2BHC A;  3FMR A;  2EVC A;  3BIT A;  1KQ9 A;  5FCF A;  1YW8 A;  4U73 A;  1N51 A;  4JUQ A;  3Q6D A;  4U1B A;  4QR8 A;  4RZY A;  1QXW A;  2V3Z A;  1XNZ A;  2BWS A;  4MAT A;  4IKU A;  2ADU A;  4Z7M A;  2B3H A;  3IU8 A;  2P99 A;  1YJ3 A;  4RZZ A;  2EA4 A;  3FM3 A;  4U6Z A;  3BIP A;  2GZ5 A;  3IG4 A;  2ZSG A;  2GU4 A;  2EVM A;  2GGC A;  4IDY A;  3RVA A;  2G6P A;  5D6E A;  4ZWP A;  3FMQ A;  1Y1N A;  3PKD A;  1WN1 A;  4PNC A;  3PKA A;  1WKM A;  2BB7 A;  4FO7 A;  5CNX A;  2BWV A;  4KM3 A;  4S01 A;  2BH3 A;  4A6W A;  2OKN A;  1QXY A;  2GG7 A;  4S2R P;  5CIK A;  2GU6 A;  2Q92 A; 
#chains in the Genus database with same CATH topology
 2BWU A;  2V3X A;  2BWX A;  4U6E A;  4FO8 A;  1BN5 A;  1W2M A;  1C23 A;  2BHB A;  2BWT A;  1CHM A;  2GTX A;  4R60 A;  4U71 A;  4IPA A;  4ZWU A;  3L24 A;  2V6C A;  2DFI A;  4U70 A;  1YW9 A;  1YVM A;  5CDV A;  2P98 A;  4FLL A;  5CDE A;  5CDL A;  2IW2 A;  4B28 A;  1C21 A;  4RGZ 1;  1W7V A;  1KP0 A;  3MAT A;  4IKS A;  1C27 A;  3L7G A;  4U6J A;  2EVO A;  2OAZ A;  3PKB A;  3CB6 A;  3MR1 A;  3ROR A;  2BWW A;  4IKR A;  1WLR A;  2Q96 A;  1C22 A;  3CB5 A;  1B6A A;  1M35 A;  2MAT A;  5JI6 A;  1C24 A;  3IU9 A;  5JFR A;  3BIQ A;  2GU5 A;  2Q95 A;  1WBQ A;  1MAT A;  4ZWO A;  4PV4 A;  2EA2 A;  3TB5 A;  1XGS A;  2GGB A;  4ZNG A;  4IU6 A;  1QZY A;  2GU7 A;  1BOA A;  5JHU A;  1WL9 A;  1YW7 A;  4U76 A;  1XGN A;  2Q8K A;  2BHD A;  4A6V A;  4FLK A;  4IKT A;  1R58 A;  2GG8 A;  1KQ0 A;  2BWY A;  2NQ7 A;  2V3Y A;  4IF7 A;  2P9A A;  2NQ6 A;  1XGM A;  4IEC A;  4FLI A;  4HXX A;  1O0X A;  5CLS A;  2Q94 A;  1R5G A;  3S6B A;  5FCH A;  3PKE A;  2BHA A;  2GG0 A;  1WY2 A;  2HOW A;  3MX6 A;  1PV9 A;  4U6C A;  1B59 A;  2GG3 A;  2GG5 A;  2GG2 A;  2Q93 A;  5CE6 A;  1QXZ A;  2GG9 A;  4U69 A;  1XGO A;  3TAV A;  1R5H A;  1JAW A;  4S00 A;  2B3L A;  4OOK A;  2B3K A;  3PKC A;  4FUK A;  3CTZ A;  4U75 A;  2GA2 A;  4EGE A;  1WL6 A;  5E5B A;  4FLJ A;  3D27 A;  3IU7 A;  1A16 A;  5D6F A;  4S2T P;  2BN7 A;  4U6W A;  4FKC A;  2BHC A;  3FMR A;  2EVC A;  3BIT A;  1KQ9 A;  5FCF A;  1YW8 A;  4U73 A;  1N51 A;  4JUQ A;  3Q6D A;  4U1B A;  4QR8 A;  4RZY A;  1QXW A;  2V3Z A;  1XNZ A;  2BWS A;  4MAT A;  4IKU A;  2ADU A;  4Z7M A;  2B3H A;  3IU8 A;  2P99 A;  1YJ3 A;  4RZZ A;  2EA4 A;  3FM3 A;  4U6Z A;  3BIP A;  2GZ5 A;  3IG4 A;  2ZSG A;  2GU4 A;  2EVM A;  2GGC A;  4IDY A;  3RVA A;  2G6P A;  5D6E A;  4ZWP A;  3FMQ A;  1Y1N A;  3PKD A;  1WN1 A;  4PNC A;  3PKA A;  1WKM A;  2BB7 A;  4FO7 A;  5CNX A;  2BWV A;  4KM3 A;  4S01 A;  2BH3 A;  4A6W A;  2OKN A;  1QXY A;  2GG7 A;  4S2R P;  5CIK A;  2GU6 A;  2Q92 A; 
#chains in the Genus database with same CATH homology
 2BWU A;  2V3X A;  2BWX A;  4U6E A;  4FO8 A;  1BN5 A;  1W2M A;  1C23 A;  2BHB A;  2BWT A;  1CHM A;  2GTX A;  4R60 A;  4U71 A;  4IPA A;  4ZWU A;  3L24 A;  2V6C A;  2DFI A;  4U70 A;  1YW9 A;  1YVM A;  5CDV A;  2P98 A;  4FLL A;  5CDE A;  5CDL A;  2IW2 A;  4B28 A;  1C21 A;  4RGZ 1;  1W7V A;  1KP0 A;  3MAT A;  4IKS A;  1C27 A;  3L7G A;  4U6J A;  2EVO A;  2OAZ A;  3PKB A;  3CB6 A;  3MR1 A;  3ROR A;  2BWW A;  4IKR A;  1WLR A;  2Q96 A;  1C22 A;  3CB5 A;  1B6A A;  1M35 A;  2MAT A;  5JI6 A;  1C24 A;  3IU9 A;  5JFR A;  3BIQ A;  2GU5 A;  2Q95 A;  1WBQ A;  1MAT A;  4ZWO A;  4PV4 A;  2EA2 A;  3TB5 A;  1XGS A;  2GGB A;  4ZNG A;  4IU6 A;  1QZY A;  2GU7 A;  1BOA A;  5JHU A;  1WL9 A;  1YW7 A;  4U76 A;  1XGN A;  2Q8K A;  2BHD A;  4A6V A;  4FLK A;  4IKT A;  1R58 A;  2GG8 A;  1KQ0 A;  2BWY A;  2NQ7 A;  2V3Y A;  4IF7 A;  2P9A A;  2NQ6 A;  1XGM A;  4IEC A;  4FLI A;  4HXX A;  1O0X A;  5CLS A;  2Q94 A;  1R5G A;  3S6B A;  5FCH A;  3PKE A;  2BHA A;  2GG0 A;  1WY2 A;  2HOW A;  3MX6 A;  1PV9 A;  4U6C A;  1B59 A;  2GG3 A;  2GG5 A;  2GG2 A;  2Q93 A;  5CE6 A;  1QXZ A;  2GG9 A;  4U69 A;  1XGO A;  3TAV A;  1R5H A;  1JAW A;  4S00 A;  2B3L A;  4OOK A;  2B3K A;  3PKC A;  4FUK A;  3CTZ A;  4U75 A;  2GA2 A;  4EGE A;  1WL6 A;  5E5B A;  4FLJ A;  3D27 A;  3IU7 A;  1A16 A;  5D6F A;  4S2T P;  2BN7 A;  4U6W A;  4FKC A;  2BHC A;  3FMR A;  2EVC A;  3BIT A;  1KQ9 A;  5FCF A;  1YW8 A;  4U73 A;  1N51 A;  4JUQ A;  3Q6D A;  4U1B A;  4QR8 A;  4RZY A;  1QXW A;  2V3Z A;  1XNZ A;  2BWS A;  4MAT A;  4IKU A;  2ADU A;  4Z7M A;  2B3H A;  3IU8 A;  2P99 A;  1YJ3 A;  4RZZ A;  2EA4 A;  3FM3 A;  4U6Z A;  3BIP A;  2GZ5 A;  3IG4 A;  2ZSG A;  2GU4 A;  2EVM A;  2GGC A;  4IDY A;  3RVA A;  2G6P A;  5D6E A;  4ZWP A;  3FMQ A;  1Y1N A;  3PKD A;  1WN1 A;  4PNC A;  3PKA A;  1WKM A;  2BB7 A;  4FO7 A;  5CNX A;  2BWV A;  4KM3 A;  4S01 A;  2BH3 A;  4A6W A;  2OKN A;  1QXY A;  2GG7 A;  4S2R P;  5CIK A;  2GU6 A;  2Q92 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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