2GU7A

E. coli methionine aminopeptidase unliganded, 1:0.5
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
261
structure length
261
Chain Sequence
SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
source organism Escherichia coli
publication title Structural basis of catalysis by monometalated methionine aminopeptidase.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
total genus 80
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2gu7A00
2V3ZA 1PV9A 4FLKA 5CDEA 1YW9A 4U71A 1Y1NA 1C27A 2BHDA 1WKMA 4A6VA 1KQ9A 5E5BA 4B28A 3FMRA 2EA4A 1QXYA 2BWWA 5CNXA 4PNCA 2ZSGA 1W2MA 2BWYA 2GGCA 2EA2A 1WLRA 5CDVA 5CDLA 3RORA 1JAWA 2BWUA 4U73A 2GG5A 4U70A 3PKEA 4IKSA 4IKTA 2BWVA 2BWTA 4ZWOA 4IECA 3TB5A 5CLSA 5JI6A 3L7GA 1O0XA 2GU5A 2DFIA 1A16A 3FM3A 2NQ6A 4PV4A 1WL6A 3RVAA 1CHMA 1XGOA 2Q8KA 5D6EA 4ZNGA 1XNZA 4IPAA 1R5GA 4ZWUA 5D6FA 1B59A 4U76A 2G6PA 4HXXA 4IF7A 2GU4A 4FO7A 4KM3A 2BWXA 4U1BA 2MATA 1YW7A 3BITA 2GG0A 1C23A 4RZZA 4EGEA 4JUQA 4MATA 2BHAA 4ZWPA 3L24A 3PKCA 4S2TP 2GG3A 4U6EA 4R60A 2GU6A 2Q92A 1BN5A 2Q95A 3IG4A 1YW8A 1QXZA 3PKDA 2HOWA 2GA2A 1R5HA 4IU6A 4U6CA 4U6ZA 2BHCA 4IKRA 2GG8A 4QR8A 2BWSA 5JHUA 3IU8A 4FKCA 4FLLA 3MATA 1WBQA 2GG2A 2GGBA 4S2RP 1C24A 3BIPA 4U6JA 5CIKA 2Q96A 4A6WA 2GG7A 5FCHA 3TAVA 1KP0A 1R58A 4RZYA 3Q6DA 2Q94A 2B3HA 2V6CA 1XGMA 2IW2A 3BIQA 2P99A 1YJ3A 3FMQA 2P98A 2P9AA 4U75A 4U69A 4Z7MA 2BH3A 4IKUA 5JFRA 5CE6A 1XGSA 2BN7A 4FLIA 1WN1A 2EVOA 2Q93A 2V3XA 2GU7A 2OKNA 3PKAA 1WY2A 1C21A 1M35A 2NQ7A 4S00A 2V3YA 3IU7A 4RGZ1 3IU9A 5FCFA 1N51A 1YVMA 2GTXA 4FO8A 1KQ0A 1QZYA 4OOKA 1B6AA 2B3LA 4FLJA 1QXWA 3CB6A 4U6WA 1C22A 1WL9A 3CTZA 1BOAA 3MR1A 1MATA 3D27A 2EVMA 1W7VA 2GZ5A 3CB5A 2B3KA 4FUKA 2OAZA 3S6BA 4S01A 4IDYA 2ADUA 2BB7A 2GG9A 2EVCA 3MX6A 3PKBA 1XGNA 2BHBA
chains in the Genus database with same CATH superfamily
2V3ZA 1PV9A 4FLKA 5CDEA 1YW9A 4U71A 1Y1NA 1C27A 2BHDA 1WKMA 4A6VA 1KQ9A 5E5BA 4B28A 3FMRA 2EA4A 1QXYA 2BWWA 5CNXA 4PNCA 2ZSGA 1W2MA 2BWYA 2GGCA 2EA2A 1WLRA 5CDVA 5CDLA 3RORA 1JAWA 2BWUA 4U73A 2GG5A 4U70A 3PKEA 4IKSA 4IKTA 2BWVA 2BWTA 4ZWOA 4IECA 3TB5A 5CLSA 5JI6A 3L7GA 1O0XA 2GU5A 2DFIA 1A16A 3FM3A 2NQ6A 4PV4A 1WL6A 3RVAA 1CHMA 1XGOA 2Q8KA 5D6EA 4ZNGA 1XNZA 4IPAA 1R5GA 4ZWUA 5D6FA 1B59A 4U76A 2G6PA 4HXXA 4IF7A 2GU4A 4FO7A 4KM3A 2BWXA 4U1BA 2MATA 1YW7A 3BITA 2GG0A 1C23A 4RZZA 4EGEA 4JUQA 4MATA 2BHAA 4ZWPA 3L24A 3PKCA 4S2TP 2GG3A 4U6EA 4R60A 2GU6A 2Q92A 1BN5A 2Q95A 3IG4A 1YW8A 1QXZA 3PKDA 2HOWA 2GA2A 1R5HA 4IU6A 4U6CA 4U6ZA 2BHCA 4IKRA 2GG8A 4QR8A 2BWSA 5JHUA 3IU8A 4FKCA 4FLLA 3MATA 1WBQA 2GG2A 2GGBA 4S2RP 1C24A 3BIPA 4U6JA 5CIKA 2Q96A 4A6WA 2GG7A 5FCHA 3TAVA 1KP0A 1R58A 4RZYA 3Q6DA 2Q94A 2B3HA 2V6CA 1XGMA 2IW2A 3BIQA 2P99A 1YJ3A 3FMQA 2P98A 2P9AA 4U75A 4U69A 4Z7MA 2BH3A 4IKUA 5JFRA 5CE6A 1XGSA 2BN7A 4FLIA 1WN1A 2EVOA 2Q93A 2V3XA 2GU7A 2OKNA 3PKAA 1WY2A 1C21A 1M35A 2NQ7A 4S00A 2V3YA 3IU7A 4RGZ1 3IU9A 5FCFA 1N51A 1YVMA 2GTXA 4FO8A 1KQ0A 1QZYA 4OOKA 1B6AA 2B3LA 4FLJA 1QXWA 3CB6A 4U6WA 1C22A 1WL9A 3CTZA 1BOAA 3MR1A 1MATA 3D27A 2EVMA 1W7VA 2GZ5A 3CB5A 2B3KA 4FUKA 2OAZA 3S6BA 4S01A 4IDYA 2ADUA 2BB7A 2GG9A 2EVCA 3MX6A 3PKBA 1XGNA 2BHBA
chains in the Genus database with same CATH topology
2V3ZA 1PV9A 4FLKA 5CDEA 1YW9A 4U71A 1Y1NA 1C27A 2BHDA 1WKMA 4A6VA 1KQ9A 5E5BA 4B28A 3FMRA 2EA4A 1QXYA 2BWWA 5CNXA 4PNCA 2ZSGA 1W2MA 2BWYA 2GGCA 2EA2A 1WLRA 5CDVA 5CDLA 3RORA 1JAWA 2BWUA 4U73A 2GG5A 4U70A 3PKEA 4IKSA 4IKTA 2BWVA 2BWTA 4ZWOA 4IECA 3TB5A 5CLSA 5JI6A 3L7GA 1O0XA 2GU5A 2DFIA 1A16A 3FM3A 2NQ6A 4PV4A 1WL6A 3RVAA 1CHMA 1XGOA 2Q8KA 5D6EA 4ZNGA 1XNZA 4IPAA 1R5GA 4ZWUA 5D6FA 1B59A 4U76A 2G6PA 4HXXA 4IF7A 2GU4A 4FO7A 4KM3A 2BWXA 4U1BA 2MATA 1YW7A 3BITA 2GG0A 1C23A 4RZZA 4EGEA 4JUQA 4MATA 2BHAA 4ZWPA 3L24A 3PKCA 4S2TP 2GG3A 4U6EA 4R60A 2GU6A 2Q92A 1BN5A 2Q95A 3IG4A 1YW8A 1QXZA 3PKDA 2HOWA 2GA2A 1R5HA 4IU6A 4U6CA 4U6ZA 2BHCA 4IKRA 2GG8A 4QR8A 2BWSA 5JHUA 3IU8A 4FKCA 4FLLA 3MATA 1WBQA 2GG2A 2GGBA 4S2RP 1C24A 3BIPA 4U6JA 5CIKA 2Q96A 4A6WA 2GG7A 5FCHA 3TAVA 1KP0A 1R58A 4RZYA 3Q6DA 2Q94A 2B3HA 2V6CA 1XGMA 2IW2A 3BIQA 2P99A 1YJ3A 3FMQA 2P98A 2P9AA 4U75A 4U69A 4Z7MA 2BH3A 4IKUA 5JFRA 5CE6A 1XGSA 2BN7A 4FLIA 1WN1A 2EVOA 2Q93A 2V3XA 2GU7A 2OKNA 3PKAA 1WY2A 1C21A 1M35A 2NQ7A 4S00A 2V3YA 3IU7A 4RGZ1 3IU9A 5FCFA 1N51A 1YVMA 2GTXA 4FO8A 1KQ0A 1QZYA 4OOKA 1B6AA 2B3LA 4FLJA 1QXWA 3CB6A 4U6WA 1C22A 1WL9A 3CTZA 1BOAA 3MR1A 1MATA 3D27A 2EVMA 1W7VA 2GZ5A 3CB5A 2B3KA 4FUKA 2OAZA 3S6BA 4S01A 4IDYA 2ADUA 2BB7A 2GG9A 2EVCA 3MX6A 3PKBA 1XGNA 2BHBA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2V3Z A;  1PV9 A;  4FLK A;  5CDE A;  1YW9 A;  4U71 A;  1Y1N A;  1C27 A;  2BHD A;  1WKM A;  4A6V A;  1KQ9 A;  5E5B A;  4B28 A;  3FMR A;  2EA4 A;  1QXY A;  2BWW A;  5CNX A;  4PNC A;  2ZSG A;  1W2M A;  2BWY A;  2GGC A;  2EA2 A;  1WLR A;  5CDV A;  5CDL A;  3ROR A;  1JAW A;  2BWU A;  4U73 A;  2GG5 A;  4U70 A;  3PKE A;  4IKS A;  4IKT A;  2BWV A;  2BWT A;  4ZWO A;  4IEC A;  3TB5 A;  5CLS A;  5JI6 A;  3L7G A;  1O0X A;  2GU5 A;  2DFI A;  1A16 A;  3FM3 A;  2NQ6 A;  4PV4 A;  1WL6 A;  3RVA A;  1CHM A;  1XGO A;  2Q8K A;  5D6E A;  4ZNG A;  1XNZ A;  4IPA A;  1R5G A;  4ZWU A;  5D6F A;  1B59 A;  4U76 A;  2G6P A;  4HXX A;  4IF7 A;  2GU4 A;  4FO7 A;  4KM3 A;  2BWX A;  4U1B A;  2MAT A;  1YW7 A;  3BIT A;  2GG0 A;  1C23 A;  4RZZ A;  4EGE A;  4JUQ A;  4MAT A;  2BHA A;  4ZWP A;  3L24 A;  3PKC A;  4S2T P;  2GG3 A;  4U6E A;  4R60 A;  2GU6 A;  2Q92 A;  1BN5 A;  2Q95 A;  3IG4 A;  1YW8 A;  1QXZ A;  3PKD A;  2HOW A;  2GA2 A;  1R5H A;  4IU6 A;  4U6C A;  4U6Z A;  2BHC A;  4IKR A;  2GG8 A;  4QR8 A;  2BWS A;  5JHU A;  3IU8 A;  4FKC A;  4FLL A;  3MAT A;  1WBQ A;  2GG2 A;  2GGB A;  4S2R P;  1C24 A;  3BIP A;  4U6J A;  5CIK A;  2Q96 A;  4A6W A;  2GG7 A;  5FCH A;  3TAV A;  1KP0 A;  1R58 A;  4RZY A;  3Q6D A;  2Q94 A;  2B3H A;  2V6C A;  1XGM A;  2IW2 A;  3BIQ A;  2P99 A;  1YJ3 A;  3FMQ A;  2P98 A;  2P9A A;  4U75 A;  4U69 A;  4Z7M A;  2BH3 A;  4IKU A;  5JFR A;  5CE6 A;  1XGS A;  2BN7 A;  4FLI A;  1WN1 A;  2EVO A;  2Q93 A;  2V3X A;  2GU7 A;  2OKN A;  3PKA A;  1WY2 A;  1C21 A;  1M35 A;  2NQ7 A;  4S00 A;  2V3Y A;  3IU7 A;  4RGZ 1;  3IU9 A;  5FCF A;  1N51 A;  1YVM A;  2GTX A;  4FO8 A;  1KQ0 A;  1QZY A;  4OOK A;  1B6A A;  2B3L A;  4FLJ A;  1QXW A;  3CB6 A;  4U6W A;  1C22 A;  1WL9 A;  3CTZ A;  1BOA A;  3MR1 A;  1MAT A;  3D27 A;  2EVM A;  1W7V A;  2GZ5 A;  3CB5 A;  2B3K A;  4FUK A;  2OAZ A;  3S6B A;  4S01 A;  4IDY A;  2ADU A;  2BB7 A;  2GG9 A;  2EVC A;  3MX6 A;  3PKB A;  1XGN A;  2BHB A; 
#chains in the Genus database with same CATH topology
 2V3Z A;  1PV9 A;  4FLK A;  5CDE A;  1YW9 A;  4U71 A;  1Y1N A;  1C27 A;  2BHD A;  1WKM A;  4A6V A;  1KQ9 A;  5E5B A;  4B28 A;  3FMR A;  2EA4 A;  1QXY A;  2BWW A;  5CNX A;  4PNC A;  2ZSG A;  1W2M A;  2BWY A;  2GGC A;  2EA2 A;  1WLR A;  5CDV A;  5CDL A;  3ROR A;  1JAW A;  2BWU A;  4U73 A;  2GG5 A;  4U70 A;  3PKE A;  4IKS A;  4IKT A;  2BWV A;  2BWT A;  4ZWO A;  4IEC A;  3TB5 A;  5CLS A;  5JI6 A;  3L7G A;  1O0X A;  2GU5 A;  2DFI A;  1A16 A;  3FM3 A;  2NQ6 A;  4PV4 A;  1WL6 A;  3RVA A;  1CHM A;  1XGO A;  2Q8K A;  5D6E A;  4ZNG A;  1XNZ A;  4IPA A;  1R5G A;  4ZWU A;  5D6F A;  1B59 A;  4U76 A;  2G6P A;  4HXX A;  4IF7 A;  2GU4 A;  4FO7 A;  4KM3 A;  2BWX A;  4U1B A;  2MAT A;  1YW7 A;  3BIT A;  2GG0 A;  1C23 A;  4RZZ A;  4EGE A;  4JUQ A;  4MAT A;  2BHA A;  4ZWP A;  3L24 A;  3PKC A;  4S2T P;  2GG3 A;  4U6E A;  4R60 A;  2GU6 A;  2Q92 A;  1BN5 A;  2Q95 A;  3IG4 A;  1YW8 A;  1QXZ A;  3PKD A;  2HOW A;  2GA2 A;  1R5H A;  4IU6 A;  4U6C A;  4U6Z A;  2BHC A;  4IKR A;  2GG8 A;  4QR8 A;  2BWS A;  5JHU A;  3IU8 A;  4FKC A;  4FLL A;  3MAT A;  1WBQ A;  2GG2 A;  2GGB A;  4S2R P;  1C24 A;  3BIP A;  4U6J A;  5CIK A;  2Q96 A;  4A6W A;  2GG7 A;  5FCH A;  3TAV A;  1KP0 A;  1R58 A;  4RZY A;  3Q6D A;  2Q94 A;  2B3H A;  2V6C A;  1XGM A;  2IW2 A;  3BIQ A;  2P99 A;  1YJ3 A;  3FMQ A;  2P98 A;  2P9A A;  4U75 A;  4U69 A;  4Z7M A;  2BH3 A;  4IKU A;  5JFR A;  5CE6 A;  1XGS A;  2BN7 A;  4FLI A;  1WN1 A;  2EVO A;  2Q93 A;  2V3X A;  2GU7 A;  2OKN A;  3PKA A;  1WY2 A;  1C21 A;  1M35 A;  2NQ7 A;  4S00 A;  2V3Y A;  3IU7 A;  4RGZ 1;  3IU9 A;  5FCF A;  1N51 A;  1YVM A;  2GTX A;  4FO8 A;  1KQ0 A;  1QZY A;  4OOK A;  1B6A A;  2B3L A;  4FLJ A;  1QXW A;  3CB6 A;  4U6W A;  1C22 A;  1WL9 A;  3CTZ A;  1BOA A;  3MR1 A;  1MAT A;  3D27 A;  2EVM A;  1W7V A;  2GZ5 A;  3CB5 A;  2B3K A;  4FUK A;  2OAZ A;  3S6B A;  4S01 A;  4IDY A;  2ADU A;  2BB7 A;  2GG9 A;  2EVC A;  3MX6 A;  3PKB A;  1XGN A;  2BHB A; 
#chains in the Genus database with same CATH homology
 2V3Z A;  1PV9 A;  4FLK A;  5CDE A;  1YW9 A;  4U71 A;  1Y1N A;  1C27 A;  2BHD A;  1WKM A;  4A6V A;  1KQ9 A;  5E5B A;  4B28 A;  3FMR A;  2EA4 A;  1QXY A;  2BWW A;  5CNX A;  4PNC A;  2ZSG A;  1W2M A;  2BWY A;  2GGC A;  2EA2 A;  1WLR A;  5CDV A;  5CDL A;  3ROR A;  1JAW A;  2BWU A;  4U73 A;  2GG5 A;  4U70 A;  3PKE A;  4IKS A;  4IKT A;  2BWV A;  2BWT A;  4ZWO A;  4IEC A;  3TB5 A;  5CLS A;  5JI6 A;  3L7G A;  1O0X A;  2GU5 A;  2DFI A;  1A16 A;  3FM3 A;  2NQ6 A;  4PV4 A;  1WL6 A;  3RVA A;  1CHM A;  1XGO A;  2Q8K A;  5D6E A;  4ZNG A;  1XNZ A;  4IPA A;  1R5G A;  4ZWU A;  5D6F A;  1B59 A;  4U76 A;  2G6P A;  4HXX A;  4IF7 A;  2GU4 A;  4FO7 A;  4KM3 A;  2BWX A;  4U1B A;  2MAT A;  1YW7 A;  3BIT A;  2GG0 A;  1C23 A;  4RZZ A;  4EGE A;  4JUQ A;  4MAT A;  2BHA A;  4ZWP A;  3L24 A;  3PKC A;  4S2T P;  2GG3 A;  4U6E A;  4R60 A;  2GU6 A;  2Q92 A;  1BN5 A;  2Q95 A;  3IG4 A;  1YW8 A;  1QXZ A;  3PKD A;  2HOW A;  2GA2 A;  1R5H A;  4IU6 A;  4U6C A;  4U6Z A;  2BHC A;  4IKR A;  2GG8 A;  4QR8 A;  2BWS A;  5JHU A;  3IU8 A;  4FKC A;  4FLL A;  3MAT A;  1WBQ A;  2GG2 A;  2GGB A;  4S2R P;  1C24 A;  3BIP A;  4U6J A;  5CIK A;  2Q96 A;  4A6W A;  2GG7 A;  5FCH A;  3TAV A;  1KP0 A;  1R58 A;  4RZY A;  3Q6D A;  2Q94 A;  2B3H A;  2V6C A;  1XGM A;  2IW2 A;  3BIQ A;  2P99 A;  1YJ3 A;  3FMQ A;  2P98 A;  2P9A A;  4U75 A;  4U69 A;  4Z7M A;  2BH3 A;  4IKU A;  5JFR A;  5CE6 A;  1XGS A;  2BN7 A;  4FLI A;  1WN1 A;  2EVO A;  2Q93 A;  2V3X A;  2GU7 A;  2OKN A;  3PKA A;  1WY2 A;  1C21 A;  1M35 A;  2NQ7 A;  4S00 A;  2V3Y A;  3IU7 A;  4RGZ 1;  3IU9 A;  5FCF A;  1N51 A;  1YVM A;  2GTX A;  4FO8 A;  1KQ0 A;  1QZY A;  4OOK A;  1B6A A;  2B3L A;  4FLJ A;  1QXW A;  3CB6 A;  4U6W A;  1C22 A;  1WL9 A;  3CTZ A;  1BOA A;  3MR1 A;  1MAT A;  3D27 A;  2EVM A;  1W7V A;  2GZ5 A;  3CB5 A;  2B3K A;  4FUK A;  2OAZ A;  3S6B A;  4S01 A;  4IDY A;  2ADU A;  2BB7 A;  2GG9 A;  2EVC A;  3MX6 A;  3PKB A;  1XGN A;  2BHB A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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