2Q93A

E. coli methionine aminopeptidase mn-form with inhibitor b21
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
263
structure length
263
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Escherichia coli
publication title Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
total genus 83
structure length 263
sequence length 263
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2q93A00
1KQ9A 2EA4A 4U75A 4IPAA 4A6VA 4PV4A 2Q93A 2OKNA 5CE6A 1XGNA 1N51A 4FLKA 1R58A 4B28A 5CDEA 4S01A 2ZSGA 2GU4A 2V3XA 5CDVA 3MR1A 4ZWUA 1B6AA 1MATA 4RZZA 4QR8A 2BHBA 1C24A 2V3ZA 5JHUA 2BHCA 2EA2A 1PV9A 1R5HA 1WL9A 2P99A 3L24A 4FLJA 1WBQA 1YW8A 1WLRA 1Y1NA 1W7VA 5CLSA 4RZYA 1KQ0A 3PKBA 4IU6A 4S00A 2GGBA 4ZWPA 5D6EA 3D27A 1O0XA 1QXZA 3CB6A 1QZYA 4IKRA 4IKUA 2EVMA 3IU8A 4FO8A 1W2MA 2BWWA 2GG3A 5JFRA 4EGEA 2GGCA 2BWYA 1XGOA 1XGSA 2BWSA 3L7GA 2BN7A 2Q8KA 4U76A 3TB5A 4U1BA 2DFIA 2Q96A 4R60A 4IKTA 3IU9A 4RGZ1 2V6CA 4FLIA 4U69A 4U6WA 2OAZA 2BWTA 2GG2A 1B59A 5FCHA 3Q6DA 5CDLA 2GU5A 2BHDA 4PNCA 1C22A 3FM3A 5D6FA 1WN1A 4IECA 4JUQA 1A16A 2GG0A 2BHAA 4U6ZA 1YW9A 1YJ3A 2NQ6A 1CHMA 2P98A 3FMQA 1C21A 2BH3A 1YW7A 2GG8A 1XNZA 3IG4A 2GU7A 2Q94A 3CB5A 2HOWA 1QXWA 1XGMA 2GZ5A 4FO7A 2Q92A 1YVMA 2B3LA 3PKDA 3MATA 1C23A 2BWUA 2G6PA 4FLLA 3FMRA 3MX6A 2BWVA 4A6WA 4U73A 3BITA 2EVOA 2Q95A 2MATA 3PKAA 4ZWOA 2P9AA 3BIQA 3TAVA 2GG7A 1BN5A 3RORA 2GU6A 5FCFA 3S6BA 1M35A 4KM3A 3RVAA 2IW2A 4U71A 3PKCA 4S2RP 2B3KA 4MATA 2NQ7A 4FKCA 1WKMA 2GG5A 4IKSA 2ADUA 4U70A 1WL6A 1KP0A 4S2TP 4IDYA 3BIPA 3PKEA 2BWXA 4U6JA 4OOKA 4U6CA 2BB7A 2GTXA 3CTZA 2V3YA 1JAWA 5JI6A 2GA2A 3IU7A 5CNXA 2EVCA 1R5GA 1WY2A 1QXYA 1BOAA 5CIKA 2B3HA 4HXXA 4IF7A 4ZNGA 5E5BA 2GG9A 4FUKA 4U6EA 1C27A 4Z7MA
chains in the Genus database with same CATH superfamily
1KQ9A 2EA4A 4U75A 4IPAA 4A6VA 4PV4A 2Q93A 2OKNA 5CE6A 1XGNA 1N51A 4FLKA 1R58A 4B28A 5CDEA 4S01A 2ZSGA 2GU4A 2V3XA 5CDVA 3MR1A 4ZWUA 1B6AA 1MATA 4RZZA 4QR8A 2BHBA 1C24A 2V3ZA 5JHUA 2BHCA 2EA2A 1PV9A 1R5HA 1WL9A 2P99A 3L24A 4FLJA 1WBQA 1YW8A 1WLRA 1Y1NA 1W7VA 5CLSA 4RZYA 1KQ0A 3PKBA 4IU6A 4S00A 2GGBA 4ZWPA 5D6EA 3D27A 1O0XA 1QXZA 3CB6A 1QZYA 4IKRA 4IKUA 2EVMA 3IU8A 4FO8A 1W2MA 2BWWA 2GG3A 5JFRA 4EGEA 2GGCA 2BWYA 1XGOA 1XGSA 2BWSA 3L7GA 2BN7A 2Q8KA 4U76A 3TB5A 4U1BA 2DFIA 2Q96A 4R60A 4IKTA 3IU9A 4RGZ1 2V6CA 4FLIA 4U69A 4U6WA 2OAZA 2BWTA 2GG2A 1B59A 5FCHA 3Q6DA 5CDLA 2GU5A 2BHDA 4PNCA 1C22A 3FM3A 5D6FA 1WN1A 4IECA 4JUQA 1A16A 2GG0A 2BHAA 4U6ZA 1YW9A 1YJ3A 2NQ6A 1CHMA 2P98A 3FMQA 1C21A 2BH3A 1YW7A 2GG8A 1XNZA 3IG4A 2GU7A 2Q94A 3CB5A 2HOWA 1QXWA 1XGMA 2GZ5A 4FO7A 2Q92A 1YVMA 2B3LA 3PKDA 3MATA 1C23A 2BWUA 2G6PA 4FLLA 3FMRA 3MX6A 2BWVA 4A6WA 4U73A 3BITA 2EVOA 2Q95A 2MATA 3PKAA 4ZWOA 2P9AA 3BIQA 3TAVA 2GG7A 1BN5A 3RORA 2GU6A 5FCFA 3S6BA 1M35A 4KM3A 3RVAA 2IW2A 4U71A 3PKCA 4S2RP 2B3KA 4MATA 2NQ7A 4FKCA 1WKMA 2GG5A 4IKSA 2ADUA 4U70A 1WL6A 1KP0A 4S2TP 4IDYA 3BIPA 3PKEA 2BWXA 4U6JA 4OOKA 4U6CA 2BB7A 2GTXA 3CTZA 2V3YA 1JAWA 5JI6A 2GA2A 3IU7A 5CNXA 2EVCA 1R5GA 1WY2A 1QXYA 1BOAA 5CIKA 2B3HA 4HXXA 4IF7A 4ZNGA 5E5BA 2GG9A 4FUKA 4U6EA 1C27A 4Z7MA
chains in the Genus database with same CATH topology
1KQ9A 2EA4A 4U75A 4IPAA 4A6VA 4PV4A 2Q93A 2OKNA 5CE6A 1XGNA 1N51A 4FLKA 1R58A 4B28A 5CDEA 4S01A 2ZSGA 2GU4A 2V3XA 5CDVA 3MR1A 4ZWUA 1B6AA 1MATA 4RZZA 4QR8A 2BHBA 1C24A 2V3ZA 5JHUA 2BHCA 2EA2A 1PV9A 1R5HA 1WL9A 2P99A 3L24A 4FLJA 1WBQA 1YW8A 1WLRA 1Y1NA 1W7VA 5CLSA 4RZYA 1KQ0A 3PKBA 4IU6A 4S00A 2GGBA 4ZWPA 5D6EA 3D27A 1O0XA 1QXZA 3CB6A 1QZYA 4IKRA 4IKUA 2EVMA 3IU8A 4FO8A 1W2MA 2BWWA 2GG3A 5JFRA 4EGEA 2GGCA 2BWYA 1XGOA 1XGSA 2BWSA 3L7GA 2BN7A 2Q8KA 4U76A 3TB5A 4U1BA 2DFIA 2Q96A 4R60A 4IKTA 3IU9A 4RGZ1 2V6CA 4FLIA 4U69A 4U6WA 2OAZA 2BWTA 2GG2A 1B59A 5FCHA 3Q6DA 5CDLA 2GU5A 2BHDA 4PNCA 1C22A 3FM3A 5D6FA 1WN1A 4IECA 4JUQA 1A16A 2GG0A 2BHAA 4U6ZA 1YW9A 1YJ3A 2NQ6A 1CHMA 2P98A 3FMQA 1C21A 2BH3A 1YW7A 2GG8A 1XNZA 3IG4A 2GU7A 2Q94A 3CB5A 2HOWA 1QXWA 1XGMA 2GZ5A 4FO7A 2Q92A 1YVMA 2B3LA 3PKDA 3MATA 1C23A 2BWUA 2G6PA 4FLLA 3FMRA 3MX6A 2BWVA 4A6WA 4U73A 3BITA 2EVOA 2Q95A 2MATA 3PKAA 4ZWOA 2P9AA 3BIQA 3TAVA 2GG7A 1BN5A 3RORA 2GU6A 5FCFA 3S6BA 1M35A 4KM3A 3RVAA 2IW2A 4U71A 3PKCA 4S2RP 2B3KA 4MATA 2NQ7A 4FKCA 1WKMA 2GG5A 4IKSA 2ADUA 4U70A 1WL6A 1KP0A 4S2TP 4IDYA 3BIPA 3PKEA 2BWXA 4U6JA 4OOKA 4U6CA 2BB7A 2GTXA 3CTZA 2V3YA 1JAWA 5JI6A 2GA2A 3IU7A 5CNXA 2EVCA 1R5GA 1WY2A 1QXYA 1BOAA 5CIKA 2B3HA 4HXXA 4IF7A 4ZNGA 5E5BA 2GG9A 4FUKA 4U6EA 1C27A 4Z7MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KQ9 A;  2EA4 A;  4U75 A;  4IPA A;  4A6V A;  4PV4 A;  2Q93 A;  2OKN A;  5CE6 A;  1XGN A;  1N51 A;  4FLK A;  1R58 A;  4B28 A;  5CDE A;  4S01 A;  2ZSG A;  2GU4 A;  2V3X A;  5CDV A;  3MR1 A;  4ZWU A;  1B6A A;  1MAT A;  4RZZ A;  4QR8 A;  2BHB A;  1C24 A;  2V3Z A;  5JHU A;  2BHC A;  2EA2 A;  1PV9 A;  1R5H A;  1WL9 A;  2P99 A;  3L24 A;  4FLJ A;  1WBQ A;  1YW8 A;  1WLR A;  1Y1N A;  1W7V A;  5CLS A;  4RZY A;  1KQ0 A;  3PKB A;  4IU6 A;  4S00 A;  2GGB A;  4ZWP A;  5D6E A;  3D27 A;  1O0X A;  1QXZ A;  3CB6 A;  1QZY A;  4IKR A;  4IKU A;  2EVM A;  3IU8 A;  4FO8 A;  1W2M A;  2BWW A;  2GG3 A;  5JFR A;  4EGE A;  2GGC A;  2BWY A;  1XGO A;  1XGS A;  2BWS A;  3L7G A;  2BN7 A;  2Q8K A;  4U76 A;  3TB5 A;  4U1B A;  2DFI A;  2Q96 A;  4R60 A;  4IKT A;  3IU9 A;  4RGZ 1;  2V6C A;  4FLI A;  4U69 A;  4U6W A;  2OAZ A;  2BWT A;  2GG2 A;  1B59 A;  5FCH A;  3Q6D A;  5CDL A;  2GU5 A;  2BHD A;  4PNC A;  1C22 A;  3FM3 A;  5D6F A;  1WN1 A;  4IEC A;  4JUQ A;  1A16 A;  2GG0 A;  2BHA A;  4U6Z A;  1YW9 A;  1YJ3 A;  2NQ6 A;  1CHM A;  2P98 A;  3FMQ A;  1C21 A;  2BH3 A;  1YW7 A;  2GG8 A;  1XNZ A;  3IG4 A;  2GU7 A;  2Q94 A;  3CB5 A;  2HOW A;  1QXW A;  1XGM A;  2GZ5 A;  4FO7 A;  2Q92 A;  1YVM A;  2B3L A;  3PKD A;  3MAT A;  1C23 A;  2BWU A;  2G6P A;  4FLL A;  3FMR A;  3MX6 A;  2BWV A;  4A6W A;  4U73 A;  3BIT A;  2EVO A;  2Q95 A;  2MAT A;  3PKA A;  4ZWO A;  2P9A A;  3BIQ A;  3TAV A;  2GG7 A;  1BN5 A;  3ROR A;  2GU6 A;  5FCF A;  3S6B A;  1M35 A;  4KM3 A;  3RVA A;  2IW2 A;  4U71 A;  3PKC A;  4S2R P;  2B3K A;  4MAT A;  2NQ7 A;  4FKC A;  1WKM A;  2GG5 A;  4IKS A;  2ADU A;  4U70 A;  1WL6 A;  1KP0 A;  4S2T P;  4IDY A;  3BIP A;  3PKE A;  2BWX A;  4U6J A;  4OOK A;  4U6C A;  2BB7 A;  2GTX A;  3CTZ A;  2V3Y A;  1JAW A;  5JI6 A;  2GA2 A;  3IU7 A;  5CNX A;  2EVC A;  1R5G A;  1WY2 A;  1QXY A;  1BOA A;  5CIK A;  2B3H A;  4HXX A;  4IF7 A;  4ZNG A;  5E5B A;  2GG9 A;  4FUK A;  4U6E A;  1C27 A;  4Z7M A; 
#chains in the Genus database with same CATH topology
 1KQ9 A;  2EA4 A;  4U75 A;  4IPA A;  4A6V A;  4PV4 A;  2Q93 A;  2OKN A;  5CE6 A;  1XGN A;  1N51 A;  4FLK A;  1R58 A;  4B28 A;  5CDE A;  4S01 A;  2ZSG A;  2GU4 A;  2V3X A;  5CDV A;  3MR1 A;  4ZWU A;  1B6A A;  1MAT A;  4RZZ A;  4QR8 A;  2BHB A;  1C24 A;  2V3Z A;  5JHU A;  2BHC A;  2EA2 A;  1PV9 A;  1R5H A;  1WL9 A;  2P99 A;  3L24 A;  4FLJ A;  1WBQ A;  1YW8 A;  1WLR A;  1Y1N A;  1W7V A;  5CLS A;  4RZY A;  1KQ0 A;  3PKB A;  4IU6 A;  4S00 A;  2GGB A;  4ZWP A;  5D6E A;  3D27 A;  1O0X A;  1QXZ A;  3CB6 A;  1QZY A;  4IKR A;  4IKU A;  2EVM A;  3IU8 A;  4FO8 A;  1W2M A;  2BWW A;  2GG3 A;  5JFR A;  4EGE A;  2GGC A;  2BWY A;  1XGO A;  1XGS A;  2BWS A;  3L7G A;  2BN7 A;  2Q8K A;  4U76 A;  3TB5 A;  4U1B A;  2DFI A;  2Q96 A;  4R60 A;  4IKT A;  3IU9 A;  4RGZ 1;  2V6C A;  4FLI A;  4U69 A;  4U6W A;  2OAZ A;  2BWT A;  2GG2 A;  1B59 A;  5FCH A;  3Q6D A;  5CDL A;  2GU5 A;  2BHD A;  4PNC A;  1C22 A;  3FM3 A;  5D6F A;  1WN1 A;  4IEC A;  4JUQ A;  1A16 A;  2GG0 A;  2BHA A;  4U6Z A;  1YW9 A;  1YJ3 A;  2NQ6 A;  1CHM A;  2P98 A;  3FMQ A;  1C21 A;  2BH3 A;  1YW7 A;  2GG8 A;  1XNZ A;  3IG4 A;  2GU7 A;  2Q94 A;  3CB5 A;  2HOW A;  1QXW A;  1XGM A;  2GZ5 A;  4FO7 A;  2Q92 A;  1YVM A;  2B3L A;  3PKD A;  3MAT A;  1C23 A;  2BWU A;  2G6P A;  4FLL A;  3FMR A;  3MX6 A;  2BWV A;  4A6W A;  4U73 A;  3BIT A;  2EVO A;  2Q95 A;  2MAT A;  3PKA A;  4ZWO A;  2P9A A;  3BIQ A;  3TAV A;  2GG7 A;  1BN5 A;  3ROR A;  2GU6 A;  5FCF A;  3S6B A;  1M35 A;  4KM3 A;  3RVA A;  2IW2 A;  4U71 A;  3PKC A;  4S2R P;  2B3K A;  4MAT A;  2NQ7 A;  4FKC A;  1WKM A;  2GG5 A;  4IKS A;  2ADU A;  4U70 A;  1WL6 A;  1KP0 A;  4S2T P;  4IDY A;  3BIP A;  3PKE A;  2BWX A;  4U6J A;  4OOK A;  4U6C A;  2BB7 A;  2GTX A;  3CTZ A;  2V3Y A;  1JAW A;  5JI6 A;  2GA2 A;  3IU7 A;  5CNX A;  2EVC A;  1R5G A;  1WY2 A;  1QXY A;  1BOA A;  5CIK A;  2B3H A;  4HXX A;  4IF7 A;  4ZNG A;  5E5B A;  2GG9 A;  4FUK A;  4U6E A;  1C27 A;  4Z7M A; 
#chains in the Genus database with same CATH homology
 1KQ9 A;  2EA4 A;  4U75 A;  4IPA A;  4A6V A;  4PV4 A;  2Q93 A;  2OKN A;  5CE6 A;  1XGN A;  1N51 A;  4FLK A;  1R58 A;  4B28 A;  5CDE A;  4S01 A;  2ZSG A;  2GU4 A;  2V3X A;  5CDV A;  3MR1 A;  4ZWU A;  1B6A A;  1MAT A;  4RZZ A;  4QR8 A;  2BHB A;  1C24 A;  2V3Z A;  5JHU A;  2BHC A;  2EA2 A;  1PV9 A;  1R5H A;  1WL9 A;  2P99 A;  3L24 A;  4FLJ A;  1WBQ A;  1YW8 A;  1WLR A;  1Y1N A;  1W7V A;  5CLS A;  4RZY A;  1KQ0 A;  3PKB A;  4IU6 A;  4S00 A;  2GGB A;  4ZWP A;  5D6E A;  3D27 A;  1O0X A;  1QXZ A;  3CB6 A;  1QZY A;  4IKR A;  4IKU A;  2EVM A;  3IU8 A;  4FO8 A;  1W2M A;  2BWW A;  2GG3 A;  5JFR A;  4EGE A;  2GGC A;  2BWY A;  1XGO A;  1XGS A;  2BWS A;  3L7G A;  2BN7 A;  2Q8K A;  4U76 A;  3TB5 A;  4U1B A;  2DFI A;  2Q96 A;  4R60 A;  4IKT A;  3IU9 A;  4RGZ 1;  2V6C A;  4FLI A;  4U69 A;  4U6W A;  2OAZ A;  2BWT A;  2GG2 A;  1B59 A;  5FCH A;  3Q6D A;  5CDL A;  2GU5 A;  2BHD A;  4PNC A;  1C22 A;  3FM3 A;  5D6F A;  1WN1 A;  4IEC A;  4JUQ A;  1A16 A;  2GG0 A;  2BHA A;  4U6Z A;  1YW9 A;  1YJ3 A;  2NQ6 A;  1CHM A;  2P98 A;  3FMQ A;  1C21 A;  2BH3 A;  1YW7 A;  2GG8 A;  1XNZ A;  3IG4 A;  2GU7 A;  2Q94 A;  3CB5 A;  2HOW A;  1QXW A;  1XGM A;  2GZ5 A;  4FO7 A;  2Q92 A;  1YVM A;  2B3L A;  3PKD A;  3MAT A;  1C23 A;  2BWU A;  2G6P A;  4FLL A;  3FMR A;  3MX6 A;  2BWV A;  4A6W A;  4U73 A;  3BIT A;  2EVO A;  2Q95 A;  2MAT A;  3PKA A;  4ZWO A;  2P9A A;  3BIQ A;  3TAV A;  2GG7 A;  1BN5 A;  3ROR A;  2GU6 A;  5FCF A;  3S6B A;  1M35 A;  4KM3 A;  3RVA A;  2IW2 A;  4U71 A;  3PKC A;  4S2R P;  2B3K A;  4MAT A;  2NQ7 A;  4FKC A;  1WKM A;  2GG5 A;  4IKS A;  2ADU A;  4U70 A;  1WL6 A;  1KP0 A;  4S2T P;  4IDY A;  3BIP A;  3PKE A;  2BWX A;  4U6J A;  4OOK A;  4U6C A;  2BB7 A;  2GTX A;  3CTZ A;  2V3Y A;  1JAW A;  5JI6 A;  2GA2 A;  3IU7 A;  5CNX A;  2EVC A;  1R5G A;  1WY2 A;  1QXY A;  1BOA A;  5CIK A;  2B3H A;  4HXX A;  4IF7 A;  4ZNG A;  5E5B A;  2GG9 A;  4FUK A;  4U6E A;  1C27 A;  4Z7M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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