2GU5A

E. coli methionine aminopeptidase in complex with nlep, 1: 1, di-metalated
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
261
structure length
261
Chain Sequence
SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of catalysis by monometalated methionine aminopeptidase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Methionine aminopeptidase
total genus 88
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2gu5A00
1BN5A 4U6ZA 1O0XA 2B3HA 3D27A 2GG9A 1PV9A 3MR1A 4PNCA 4JUQA 5CIKA 2BHAA 4S00A 1JAWA 2HOWA 2Q92A 3IU9A 3BIPA 5E5BA 2GG8A 2BWYA 4KM3A 1C27A 1YVMA 2Q95A 5JFRA 3FMQA 2GU4A 1W7VA 1N51A 1R58A 1KP0A 1WN1A 4ZNGA 4IPAA 4U71A 2BWUA 2GG5A 4MATA 2OKNA 1YW8A 5D6EA 1C23A 4A6VA 4EGEA 2BH3A 3IU7A 4FUKA 1W2MA 4U1BA 1XNZA 4S2RP 1KQ9A 3BIQA 4FLLA 4U70A 1YW7A 5D6FA 1WL6A 2GU6A 5CDVA 2EA4A 1B6AA 2Q96A 3MATA 4U6WA 2BWXA 3TAVA 4FO7A 4IKRA 4RZYA 1YW9A 3TB5A 2GG3A 2EA2A 5CNXA 4IKSA 2BHDA 4IDYA 4FO8A 4U73A 2P99A 2V3XA 2BWSA 2ZSGA 4HXXA 2GGBA 5CE6A 1XGMA 4RZZA 4FKCA 1C24A 1B59A 1WKMA 4OOKA 1CHMA 2GTXA 2GG0A 2GU7A 1R5HA 1QXWA 4FLJA 2IW2A 2BHCA 3Q6DA 2B3LA 2GU5A 4FLKA 1R5GA 2MATA 2B3KA 2BB7A 4U75A 2P9AA 3L7GA 4IECA 2EVMA 2GG2A 3CTZA 2EVCA 2GA2A 2BN7A 3RORA 2V6CA 4S2TP 2ADUA 1KQ0A 4FLIA 2EVOA 4B28A 3FM3A 3S6BA 1BOAA 1XGNA 2G6PA 3PKAA 4S01A 1WY2A 2GGCA 4Z7MA 1QXYA 1Y1NA 4IF7A 3MX6A 3FMRA 5JI6A 5CDLA 3BITA 3PKDA 1YJ3A 4IU6A 4A6WA 5CLSA 5CDEA 2Q93A 4PV4A 1QXZA 2Q8KA 1A16A 2V3YA 4U6JA 1QZYA 2GZ5A 3IG4A 1C21A 4U6CA 1WLRA 1MATA 4QR8A 4IKUA 2DFIA 2BWVA 2BWTA 4U69A 3PKBA 2P98A 4RGZ1 2OAZA 5JHUA 1C22A 1WBQA 1M35A 2NQ7A 3CB5A 3PKEA 4U6EA 5FCFA 1XGOA 2NQ6A 2V3ZA 1WL9A 1XGSA 2BHBA 4IKTA 5FCHA 4ZWPA 3L24A 3CB6A 3IU8A 4U76A 4ZWOA 4R60A 2BWWA 2GG7A 4ZWUA 2Q94A 3RVAA 3PKCA
chains in the Genus database with same CATH superfamily
1BN5A 4U6ZA 1O0XA 2B3HA 3D27A 2GG9A 1PV9A 3MR1A 4PNCA 4JUQA 5CIKA 2BHAA 4S00A 1JAWA 2HOWA 2Q92A 3IU9A 3BIPA 5E5BA 2GG8A 2BWYA 4KM3A 1C27A 1YVMA 2Q95A 5JFRA 3FMQA 2GU4A 1W7VA 1N51A 1R58A 1KP0A 1WN1A 4ZNGA 4IPAA 4U71A 2BWUA 2GG5A 4MATA 2OKNA 1YW8A 5D6EA 1C23A 4A6VA 4EGEA 2BH3A 3IU7A 4FUKA 1W2MA 4U1BA 1XNZA 4S2RP 1KQ9A 3BIQA 4FLLA 4U70A 1YW7A 5D6FA 1WL6A 2GU6A 5CDVA 2EA4A 1B6AA 2Q96A 3MATA 4U6WA 2BWXA 3TAVA 4FO7A 4IKRA 4RZYA 1YW9A 3TB5A 2GG3A 2EA2A 5CNXA 4IKSA 2BHDA 4IDYA 4FO8A 4U73A 2P99A 2V3XA 2BWSA 2ZSGA 4HXXA 2GGBA 5CE6A 1XGMA 4RZZA 4FKCA 1C24A 1B59A 1WKMA 4OOKA 1CHMA 2GTXA 2GG0A 2GU7A 1R5HA 1QXWA 4FLJA 2IW2A 2BHCA 3Q6DA 2B3LA 2GU5A 4FLKA 1R5GA 2MATA 2B3KA 2BB7A 4U75A 2P9AA 3L7GA 4IECA 2EVMA 2GG2A 3CTZA 2EVCA 2GA2A 2BN7A 3RORA 2V6CA 4S2TP 2ADUA 1KQ0A 4FLIA 2EVOA 4B28A 3FM3A 3S6BA 1BOAA 1XGNA 2G6PA 3PKAA 4S01A 1WY2A 2GGCA 4Z7MA 1QXYA 1Y1NA 4IF7A 3MX6A 3FMRA 5JI6A 5CDLA 3BITA 3PKDA 1YJ3A 4IU6A 4A6WA 5CLSA 5CDEA 2Q93A 4PV4A 1QXZA 2Q8KA 1A16A 2V3YA 4U6JA 1QZYA 2GZ5A 3IG4A 1C21A 4U6CA 1WLRA 1MATA 4QR8A 4IKUA 2DFIA 2BWVA 2BWTA 4U69A 3PKBA 2P98A 4RGZ1 2OAZA 5JHUA 1C22A 1WBQA 1M35A 2NQ7A 3CB5A 3PKEA 4U6EA 5FCFA 1XGOA 2NQ6A 2V3ZA 1WL9A 1XGSA 2BHBA 4IKTA 5FCHA 4ZWPA 3L24A 3CB6A 3IU8A 4U76A 4ZWOA 4R60A 2BWWA 2GG7A 4ZWUA 2Q94A 3RVAA 3PKCA
chains in the Genus database with same CATH topology
1BN5A 4U6ZA 1O0XA 2B3HA 3D27A 2GG9A 1PV9A 3MR1A 4PNCA 4JUQA 5CIKA 2BHAA 4S00A 1JAWA 2HOWA 2Q92A 3IU9A 3BIPA 5E5BA 2GG8A 2BWYA 4KM3A 1C27A 1YVMA 2Q95A 5JFRA 3FMQA 2GU4A 1W7VA 1N51A 1R58A 1KP0A 1WN1A 4ZNGA 4IPAA 4U71A 2BWUA 2GG5A 4MATA 2OKNA 1YW8A 5D6EA 1C23A 4A6VA 4EGEA 2BH3A 3IU7A 4FUKA 1W2MA 4U1BA 1XNZA 4S2RP 1KQ9A 3BIQA 4FLLA 4U70A 1YW7A 5D6FA 1WL6A 2GU6A 5CDVA 2EA4A 1B6AA 2Q96A 3MATA 4U6WA 2BWXA 3TAVA 4FO7A 4IKRA 4RZYA 1YW9A 3TB5A 2GG3A 2EA2A 5CNXA 4IKSA 2BHDA 4IDYA 4FO8A 4U73A 2P99A 2V3XA 2BWSA 2ZSGA 4HXXA 2GGBA 5CE6A 1XGMA 4RZZA 4FKCA 1C24A 1B59A 1WKMA 4OOKA 1CHMA 2GTXA 2GG0A 2GU7A 1R5HA 1QXWA 4FLJA 2IW2A 2BHCA 3Q6DA 2B3LA 2GU5A 4FLKA 1R5GA 2MATA 2B3KA 2BB7A 4U75A 2P9AA 3L7GA 4IECA 2EVMA 2GG2A 3CTZA 2EVCA 2GA2A 2BN7A 3RORA 2V6CA 4S2TP 2ADUA 1KQ0A 4FLIA 2EVOA 4B28A 3FM3A 3S6BA 1BOAA 1XGNA 2G6PA 3PKAA 4S01A 1WY2A 2GGCA 4Z7MA 1QXYA 1Y1NA 4IF7A 3MX6A 3FMRA 5JI6A 5CDLA 3BITA 3PKDA 1YJ3A 4IU6A 4A6WA 5CLSA 5CDEA 2Q93A 4PV4A 1QXZA 2Q8KA 1A16A 2V3YA 4U6JA 1QZYA 2GZ5A 3IG4A 1C21A 4U6CA 1WLRA 1MATA 4QR8A 4IKUA 2DFIA 2BWVA 2BWTA 4U69A 3PKBA 2P98A 4RGZ1 2OAZA 5JHUA 1C22A 1WBQA 1M35A 2NQ7A 3CB5A 3PKEA 4U6EA 5FCFA 1XGOA 2NQ6A 2V3ZA 1WL9A 1XGSA 2BHBA 4IKTA 5FCHA 4ZWPA 3L24A 3CB6A 3IU8A 4U76A 4ZWOA 4R60A 2BWWA 2GG7A 4ZWUA 2Q94A 3RVAA 3PKCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BN5 A;  4U6Z A;  1O0X A;  2B3H A;  3D27 A;  2GG9 A;  1PV9 A;  3MR1 A;  4PNC A;  4JUQ A;  5CIK A;  2BHA A;  4S00 A;  1JAW A;  2HOW A;  2Q92 A;  3IU9 A;  3BIP A;  5E5B A;  2GG8 A;  2BWY A;  4KM3 A;  1C27 A;  1YVM A;  2Q95 A;  5JFR A;  3FMQ A;  2GU4 A;  1W7V A;  1N51 A;  1R58 A;  1KP0 A;  1WN1 A;  4ZNG A;  4IPA A;  4U71 A;  2BWU A;  2GG5 A;  4MAT A;  2OKN A;  1YW8 A;  5D6E A;  1C23 A;  4A6V A;  4EGE A;  2BH3 A;  3IU7 A;  4FUK A;  1W2M A;  4U1B A;  1XNZ A;  4S2R P;  1KQ9 A;  3BIQ A;  4FLL A;  4U70 A;  1YW7 A;  5D6F A;  1WL6 A;  2GU6 A;  5CDV A;  2EA4 A;  1B6A A;  2Q96 A;  3MAT A;  4U6W A;  2BWX A;  3TAV A;  4FO7 A;  4IKR A;  4RZY A;  1YW9 A;  3TB5 A;  2GG3 A;  2EA2 A;  5CNX A;  4IKS A;  2BHD A;  4IDY A;  4FO8 A;  4U73 A;  2P99 A;  2V3X A;  2BWS A;  2ZSG A;  4HXX A;  2GGB A;  5CE6 A;  1XGM A;  4RZZ A;  4FKC A;  1C24 A;  1B59 A;  1WKM A;  4OOK A;  1CHM A;  2GTX A;  2GG0 A;  2GU7 A;  1R5H A;  1QXW A;  4FLJ A;  2IW2 A;  2BHC A;  3Q6D A;  2B3L A;  2GU5 A;  4FLK A;  1R5G A;  2MAT A;  2B3K A;  2BB7 A;  4U75 A;  2P9A A;  3L7G A;  4IEC A;  2EVM A;  2GG2 A;  3CTZ A;  2EVC A;  2GA2 A;  2BN7 A;  3ROR A;  2V6C A;  4S2T P;  2ADU A;  1KQ0 A;  4FLI A;  2EVO A;  4B28 A;  3FM3 A;  3S6B A;  1BOA A;  1XGN A;  2G6P A;  3PKA A;  4S01 A;  1WY2 A;  2GGC A;  4Z7M A;  1QXY A;  1Y1N A;  4IF7 A;  3MX6 A;  3FMR A;  5JI6 A;  5CDL A;  3BIT A;  3PKD A;  1YJ3 A;  4IU6 A;  4A6W A;  5CLS A;  5CDE A;  2Q93 A;  4PV4 A;  1QXZ A;  2Q8K A;  1A16 A;  2V3Y A;  4U6J A;  1QZY A;  2GZ5 A;  3IG4 A;  1C21 A;  4U6C A;  1WLR A;  1MAT A;  4QR8 A;  4IKU A;  2DFI A;  2BWV A;  2BWT A;  4U69 A;  3PKB A;  2P98 A;  4RGZ 1;  2OAZ A;  5JHU A;  1C22 A;  1WBQ A;  1M35 A;  2NQ7 A;  3CB5 A;  3PKE A;  4U6E A;  5FCF A;  1XGO A;  2NQ6 A;  2V3Z A;  1WL9 A;  1XGS A;  2BHB A;  4IKT A;  5FCH A;  4ZWP A;  3L24 A;  3CB6 A;  3IU8 A;  4U76 A;  4ZWO A;  4R60 A;  2BWW A;  2GG7 A;  4ZWU A;  2Q94 A;  3RVA A;  3PKC A; 
#chains in the Genus database with same CATH topology
 1BN5 A;  4U6Z A;  1O0X A;  2B3H A;  3D27 A;  2GG9 A;  1PV9 A;  3MR1 A;  4PNC A;  4JUQ A;  5CIK A;  2BHA A;  4S00 A;  1JAW A;  2HOW A;  2Q92 A;  3IU9 A;  3BIP A;  5E5B A;  2GG8 A;  2BWY A;  4KM3 A;  1C27 A;  1YVM A;  2Q95 A;  5JFR A;  3FMQ A;  2GU4 A;  1W7V A;  1N51 A;  1R58 A;  1KP0 A;  1WN1 A;  4ZNG A;  4IPA A;  4U71 A;  2BWU A;  2GG5 A;  4MAT A;  2OKN A;  1YW8 A;  5D6E A;  1C23 A;  4A6V A;  4EGE A;  2BH3 A;  3IU7 A;  4FUK A;  1W2M A;  4U1B A;  1XNZ A;  4S2R P;  1KQ9 A;  3BIQ A;  4FLL A;  4U70 A;  1YW7 A;  5D6F A;  1WL6 A;  2GU6 A;  5CDV A;  2EA4 A;  1B6A A;  2Q96 A;  3MAT A;  4U6W A;  2BWX A;  3TAV A;  4FO7 A;  4IKR A;  4RZY A;  1YW9 A;  3TB5 A;  2GG3 A;  2EA2 A;  5CNX A;  4IKS A;  2BHD A;  4IDY A;  4FO8 A;  4U73 A;  2P99 A;  2V3X A;  2BWS A;  2ZSG A;  4HXX A;  2GGB A;  5CE6 A;  1XGM A;  4RZZ A;  4FKC A;  1C24 A;  1B59 A;  1WKM A;  4OOK A;  1CHM A;  2GTX A;  2GG0 A;  2GU7 A;  1R5H A;  1QXW A;  4FLJ A;  2IW2 A;  2BHC A;  3Q6D A;  2B3L A;  2GU5 A;  4FLK A;  1R5G A;  2MAT A;  2B3K A;  2BB7 A;  4U75 A;  2P9A A;  3L7G A;  4IEC A;  2EVM A;  2GG2 A;  3CTZ A;  2EVC A;  2GA2 A;  2BN7 A;  3ROR A;  2V6C A;  4S2T P;  2ADU A;  1KQ0 A;  4FLI A;  2EVO A;  4B28 A;  3FM3 A;  3S6B A;  1BOA A;  1XGN A;  2G6P A;  3PKA A;  4S01 A;  1WY2 A;  2GGC A;  4Z7M A;  1QXY A;  1Y1N A;  4IF7 A;  3MX6 A;  3FMR A;  5JI6 A;  5CDL A;  3BIT A;  3PKD A;  1YJ3 A;  4IU6 A;  4A6W A;  5CLS A;  5CDE A;  2Q93 A;  4PV4 A;  1QXZ A;  2Q8K A;  1A16 A;  2V3Y A;  4U6J A;  1QZY A;  2GZ5 A;  3IG4 A;  1C21 A;  4U6C A;  1WLR A;  1MAT A;  4QR8 A;  4IKU A;  2DFI A;  2BWV A;  2BWT A;  4U69 A;  3PKB A;  2P98 A;  4RGZ 1;  2OAZ A;  5JHU A;  1C22 A;  1WBQ A;  1M35 A;  2NQ7 A;  3CB5 A;  3PKE A;  4U6E A;  5FCF A;  1XGO A;  2NQ6 A;  2V3Z A;  1WL9 A;  1XGS A;  2BHB A;  4IKT A;  5FCH A;  4ZWP A;  3L24 A;  3CB6 A;  3IU8 A;  4U76 A;  4ZWO A;  4R60 A;  2BWW A;  2GG7 A;  4ZWU A;  2Q94 A;  3RVA A;  3PKC A; 
#chains in the Genus database with same CATH homology
 1BN5 A;  4U6Z A;  1O0X A;  2B3H A;  3D27 A;  2GG9 A;  1PV9 A;  3MR1 A;  4PNC A;  4JUQ A;  5CIK A;  2BHA A;  4S00 A;  1JAW A;  2HOW A;  2Q92 A;  3IU9 A;  3BIP A;  5E5B A;  2GG8 A;  2BWY A;  4KM3 A;  1C27 A;  1YVM A;  2Q95 A;  5JFR A;  3FMQ A;  2GU4 A;  1W7V A;  1N51 A;  1R58 A;  1KP0 A;  1WN1 A;  4ZNG A;  4IPA A;  4U71 A;  2BWU A;  2GG5 A;  4MAT A;  2OKN A;  1YW8 A;  5D6E A;  1C23 A;  4A6V A;  4EGE A;  2BH3 A;  3IU7 A;  4FUK A;  1W2M A;  4U1B A;  1XNZ A;  4S2R P;  1KQ9 A;  3BIQ A;  4FLL A;  4U70 A;  1YW7 A;  5D6F A;  1WL6 A;  2GU6 A;  5CDV A;  2EA4 A;  1B6A A;  2Q96 A;  3MAT A;  4U6W A;  2BWX A;  3TAV A;  4FO7 A;  4IKR A;  4RZY A;  1YW9 A;  3TB5 A;  2GG3 A;  2EA2 A;  5CNX A;  4IKS A;  2BHD A;  4IDY A;  4FO8 A;  4U73 A;  2P99 A;  2V3X A;  2BWS A;  2ZSG A;  4HXX A;  2GGB A;  5CE6 A;  1XGM A;  4RZZ A;  4FKC A;  1C24 A;  1B59 A;  1WKM A;  4OOK A;  1CHM A;  2GTX A;  2GG0 A;  2GU7 A;  1R5H A;  1QXW A;  4FLJ A;  2IW2 A;  2BHC A;  3Q6D A;  2B3L A;  2GU5 A;  4FLK A;  1R5G A;  2MAT A;  2B3K A;  2BB7 A;  4U75 A;  2P9A A;  3L7G A;  4IEC A;  2EVM A;  2GG2 A;  3CTZ A;  2EVC A;  2GA2 A;  2BN7 A;  3ROR A;  2V6C A;  4S2T P;  2ADU A;  1KQ0 A;  4FLI A;  2EVO A;  4B28 A;  3FM3 A;  3S6B A;  1BOA A;  1XGN A;  2G6P A;  3PKA A;  4S01 A;  1WY2 A;  2GGC A;  4Z7M A;  1QXY A;  1Y1N A;  4IF7 A;  3MX6 A;  3FMR A;  5JI6 A;  5CDL A;  3BIT A;  3PKD A;  1YJ3 A;  4IU6 A;  4A6W A;  5CLS A;  5CDE A;  2Q93 A;  4PV4 A;  1QXZ A;  2Q8K A;  1A16 A;  2V3Y A;  4U6J A;  1QZY A;  2GZ5 A;  3IG4 A;  1C21 A;  4U6C A;  1WLR A;  1MAT A;  4QR8 A;  4IKU A;  2DFI A;  2BWV A;  2BWT A;  4U69 A;  3PKB A;  2P98 A;  4RGZ 1;  2OAZ A;  5JHU A;  1C22 A;  1WBQ A;  1M35 A;  2NQ7 A;  3CB5 A;  3PKE A;  4U6E A;  5FCF A;  1XGO A;  2NQ6 A;  2V3Z A;  1WL9 A;  1XGS A;  2BHB A;  4IKT A;  5FCH A;  4ZWP A;  3L24 A;  3CB6 A;  3IU8 A;  4U76 A;  4ZWO A;  4R60 A;  2BWW A;  2GG7 A;  4ZWU A;  2Q94 A;  3RVA A;  3PKC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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