2GU6A

E. coli methionine aminopeptidase in complex with nlep, 1: 2, di-metalated
Total Genus 92
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
261
structure length
261
Chain Sequence
SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural basis of catalysis by monometalated methionine aminopeptidase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Methionine aminopeptidase
total genus 92
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2006-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2gu6A00
1YW8A 3D27A 4IKTA 5E5BA 3BIQA 2GG8A 5CE6A 3CTZA 3FMRA 4IECA 2BH3A 3PKEA 5FCHA 1W2MA 2GGBA 2P99A 2BWYA 4RZYA 2B3LA 2BWTA 4U6CA 1WKMA 3TB5A 4U75A 2MATA 2ADUA 4FLJA 5D6EA 2GU4A 3RORA 1QXWA 1R58A 4U70A 1WN1A 4U6WA 5JI6A 2EVCA 4U73A 3FMQA 2GG5A 3MX6A 3MATA 4FLIA 4IU6A 4ZNGA 2B3HA 4PV4A 2EVOA 1WL9A 1C21A 4MATA 1JAWA 2BWWA 2V3XA 4IDYA 1YVMA 1XNZA 4IKUA 4S2RP 4QR8A 4A6WA 5CDVA 1O0XA 2BHAA 5JHUA 1CHMA 2G6PA 4S01A 4IKRA 1KQ0A 2IW2A 2V3YA 1C24A 1C27A 4KM3A 4IKSA 2GG3A 2BWXA 2BHDA 4B28A 4PNCA 3L24A 4R60A 2GG0A 2GZ5A 5CLSA 4ZWOA 1C23A 4JUQA 1PV9A 3PKDA 4FO7A 1MATA 4U6EA 2OKNA 2P9AA 2EA2A 5FCFA 2EVMA 2GGCA 2GG7A 2Q92A 2V6CA 1KP0A 3CB5A 4U1BA 4Z7MA 1QZYA 2GG9A 2BHBA 2GTXA 2BWSA 4EGEA 3CB6A 4ZWUA 4FUKA 4U6ZA 1XGNA 4IPAA 2BWUA 2BB7A 1XGMA 2P98A 1XGSA 2ZSGA 5JFRA 4FO8A 4U71A 2B3KA 1B59A 3TAVA 2NQ7A 2Q96A 3IU9A 3IU7A 5D6FA 1Y1NA 2BHCA 2GU7A 1QXYA 4OOKA 4U69A 4RGZ1 4U76A 5CNXA 3MR1A 4RZZA 2EA4A 3Q6DA 2DFIA 4S2TP 1B6AA 2V3ZA 3PKBA 2Q95A 2OAZA 4HXXA 1R5HA 1C22A 2NQ6A 2Q93A 4A6VA 3L7GA 1A16A 1QXZA 2BWVA 2Q94A 3PKAA 3RVAA 2GG2A 3PKCA 1W7VA 5CDEA 2GA2A 1N51A 1WY2A 4FLLA 5CDLA 1YW7A 4ZWPA 1BN5A 4S00A 1YW9A 1WLRA 2BN7A 2HOWA 1XGOA 3FM3A 3IG4A 2GU5A 4FLKA 1WL6A 3S6BA 1YJ3A 1M35A 1R5GA 3BIPA 4IF7A 1KQ9A 2Q8KA 3BITA 1BOAA 3IU8A 4U6JA 4FKCA 1WBQA 2GU6A 5CIKA
chains in the Genus database with same CATH superfamily
1YW8A 3D27A 4IKTA 5E5BA 3BIQA 2GG8A 5CE6A 3CTZA 3FMRA 4IECA 2BH3A 3PKEA 5FCHA 1W2MA 2GGBA 2P99A 2BWYA 4RZYA 2B3LA 2BWTA 4U6CA 1WKMA 3TB5A 4U75A 2MATA 2ADUA 4FLJA 5D6EA 2GU4A 3RORA 1QXWA 1R58A 4U70A 1WN1A 4U6WA 5JI6A 2EVCA 4U73A 3FMQA 2GG5A 3MX6A 3MATA 4FLIA 4IU6A 4ZNGA 2B3HA 4PV4A 2EVOA 1WL9A 1C21A 4MATA 1JAWA 2BWWA 2V3XA 4IDYA 1YVMA 1XNZA 4IKUA 4S2RP 4QR8A 4A6WA 5CDVA 1O0XA 2BHAA 5JHUA 1CHMA 2G6PA 4S01A 4IKRA 1KQ0A 2IW2A 2V3YA 1C24A 1C27A 4KM3A 4IKSA 2GG3A 2BWXA 2BHDA 4B28A 4PNCA 3L24A 4R60A 2GG0A 2GZ5A 5CLSA 4ZWOA 1C23A 4JUQA 1PV9A 3PKDA 4FO7A 1MATA 4U6EA 2OKNA 2P9AA 2EA2A 5FCFA 2EVMA 2GGCA 2GG7A 2Q92A 2V6CA 1KP0A 3CB5A 4U1BA 4Z7MA 1QZYA 2GG9A 2BHBA 2GTXA 2BWSA 4EGEA 3CB6A 4ZWUA 4FUKA 4U6ZA 1XGNA 4IPAA 2BWUA 2BB7A 1XGMA 2P98A 1XGSA 2ZSGA 5JFRA 4FO8A 4U71A 2B3KA 1B59A 3TAVA 2NQ7A 2Q96A 3IU9A 3IU7A 5D6FA 1Y1NA 2BHCA 2GU7A 1QXYA 4OOKA 4U69A 4RGZ1 4U76A 5CNXA 3MR1A 4RZZA 2EA4A 3Q6DA 2DFIA 4S2TP 1B6AA 2V3ZA 3PKBA 2Q95A 2OAZA 4HXXA 1R5HA 1C22A 2NQ6A 2Q93A 4A6VA 3L7GA 1A16A 1QXZA 2BWVA 2Q94A 3PKAA 3RVAA 2GG2A 3PKCA 1W7VA 5CDEA 2GA2A 1N51A 1WY2A 4FLLA 5CDLA 1YW7A 4ZWPA 1BN5A 4S00A 1YW9A 1WLRA 2BN7A 2HOWA 1XGOA 3FM3A 3IG4A 2GU5A 4FLKA 1WL6A 3S6BA 1YJ3A 1M35A 1R5GA 3BIPA 4IF7A 1KQ9A 2Q8KA 3BITA 1BOAA 3IU8A 4U6JA 4FKCA 1WBQA 2GU6A 5CIKA
chains in the Genus database with same CATH topology
1YW8A 3D27A 4IKTA 5E5BA 3BIQA 2GG8A 5CE6A 3CTZA 3FMRA 4IECA 2BH3A 3PKEA 5FCHA 1W2MA 2GGBA 2P99A 2BWYA 4RZYA 2B3LA 2BWTA 4U6CA 1WKMA 3TB5A 4U75A 2MATA 2ADUA 4FLJA 5D6EA 2GU4A 3RORA 1QXWA 1R58A 4U70A 1WN1A 4U6WA 5JI6A 2EVCA 4U73A 3FMQA 2GG5A 3MX6A 3MATA 4FLIA 4IU6A 4ZNGA 2B3HA 4PV4A 2EVOA 1WL9A 1C21A 4MATA 1JAWA 2BWWA 2V3XA 4IDYA 1YVMA 1XNZA 4IKUA 4S2RP 4QR8A 4A6WA 5CDVA 1O0XA 2BHAA 5JHUA 1CHMA 2G6PA 4S01A 4IKRA 1KQ0A 2IW2A 2V3YA 1C24A 1C27A 4KM3A 4IKSA 2GG3A 2BWXA 2BHDA 4B28A 4PNCA 3L24A 4R60A 2GG0A 2GZ5A 5CLSA 4ZWOA 1C23A 4JUQA 1PV9A 3PKDA 4FO7A 1MATA 4U6EA 2OKNA 2P9AA 2EA2A 5FCFA 2EVMA 2GGCA 2GG7A 2Q92A 2V6CA 1KP0A 3CB5A 4U1BA 4Z7MA 1QZYA 2GG9A 2BHBA 2GTXA 2BWSA 4EGEA 3CB6A 4ZWUA 4FUKA 4U6ZA 1XGNA 4IPAA 2BWUA 2BB7A 1XGMA 2P98A 1XGSA 2ZSGA 5JFRA 4FO8A 4U71A 2B3KA 1B59A 3TAVA 2NQ7A 2Q96A 3IU9A 3IU7A 5D6FA 1Y1NA 2BHCA 2GU7A 1QXYA 4OOKA 4U69A 4RGZ1 4U76A 5CNXA 3MR1A 4RZZA 2EA4A 3Q6DA 2DFIA 4S2TP 1B6AA 2V3ZA 3PKBA 2Q95A 2OAZA 4HXXA 1R5HA 1C22A 2NQ6A 2Q93A 4A6VA 3L7GA 1A16A 1QXZA 2BWVA 2Q94A 3PKAA 3RVAA 2GG2A 3PKCA 1W7VA 5CDEA 2GA2A 1N51A 1WY2A 4FLLA 5CDLA 1YW7A 4ZWPA 1BN5A 4S00A 1YW9A 1WLRA 2BN7A 2HOWA 1XGOA 3FM3A 3IG4A 2GU5A 4FLKA 1WL6A 3S6BA 1YJ3A 1M35A 1R5GA 3BIPA 4IF7A 1KQ9A 2Q8KA 3BITA 1BOAA 3IU8A 4U6JA 4FKCA 1WBQA 2GU6A 5CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YW8 A;  3D27 A;  4IKT A;  5E5B A;  3BIQ A;  2GG8 A;  5CE6 A;  3CTZ A;  3FMR A;  4IEC A;  2BH3 A;  3PKE A;  5FCH A;  1W2M A;  2GGB A;  2P99 A;  2BWY A;  4RZY A;  2B3L A;  2BWT A;  4U6C A;  1WKM A;  3TB5 A;  4U75 A;  2MAT A;  2ADU A;  4FLJ A;  5D6E A;  2GU4 A;  3ROR A;  1QXW A;  1R58 A;  4U70 A;  1WN1 A;  4U6W A;  5JI6 A;  2EVC A;  4U73 A;  3FMQ A;  2GG5 A;  3MX6 A;  3MAT A;  4FLI A;  4IU6 A;  4ZNG A;  2B3H A;  4PV4 A;  2EVO A;  1WL9 A;  1C21 A;  4MAT A;  1JAW A;  2BWW A;  2V3X A;  4IDY A;  1YVM A;  1XNZ A;  4IKU A;  4S2R P;  4QR8 A;  4A6W A;  5CDV A;  1O0X A;  2BHA A;  5JHU A;  1CHM A;  2G6P A;  4S01 A;  4IKR A;  1KQ0 A;  2IW2 A;  2V3Y A;  1C24 A;  1C27 A;  4KM3 A;  4IKS A;  2GG3 A;  2BWX A;  2BHD A;  4B28 A;  4PNC A;  3L24 A;  4R60 A;  2GG0 A;  2GZ5 A;  5CLS A;  4ZWO A;  1C23 A;  4JUQ A;  1PV9 A;  3PKD A;  4FO7 A;  1MAT A;  4U6E A;  2OKN A;  2P9A A;  2EA2 A;  5FCF A;  2EVM A;  2GGC A;  2GG7 A;  2Q92 A;  2V6C A;  1KP0 A;  3CB5 A;  4U1B A;  4Z7M A;  1QZY A;  2GG9 A;  2BHB A;  2GTX A;  2BWS A;  4EGE A;  3CB6 A;  4ZWU A;  4FUK A;  4U6Z A;  1XGN A;  4IPA A;  2BWU A;  2BB7 A;  1XGM A;  2P98 A;  1XGS A;  2ZSG A;  5JFR A;  4FO8 A;  4U71 A;  2B3K A;  1B59 A;  3TAV A;  2NQ7 A;  2Q96 A;  3IU9 A;  3IU7 A;  5D6F A;  1Y1N A;  2BHC A;  2GU7 A;  1QXY A;  4OOK A;  4U69 A;  4RGZ 1;  4U76 A;  5CNX A;  3MR1 A;  4RZZ A;  2EA4 A;  3Q6D A;  2DFI A;  4S2T P;  1B6A A;  2V3Z A;  3PKB A;  2Q95 A;  2OAZ A;  4HXX A;  1R5H A;  1C22 A;  2NQ6 A;  2Q93 A;  4A6V A;  3L7G A;  1A16 A;  1QXZ A;  2BWV A;  2Q94 A;  3PKA A;  3RVA A;  2GG2 A;  3PKC A;  1W7V A;  5CDE A;  2GA2 A;  1N51 A;  1WY2 A;  4FLL A;  5CDL A;  1YW7 A;  4ZWP A;  1BN5 A;  4S00 A;  1YW9 A;  1WLR A;  2BN7 A;  2HOW A;  1XGO A;  3FM3 A;  3IG4 A;  2GU5 A;  4FLK A;  1WL6 A;  3S6B A;  1YJ3 A;  1M35 A;  1R5G A;  3BIP A;  4IF7 A;  1KQ9 A;  2Q8K A;  3BIT A;  1BOA A;  3IU8 A;  4U6J A;  4FKC A;  1WBQ A;  2GU6 A;  5CIK A; 
#chains in the Genus database with same CATH topology
 1YW8 A;  3D27 A;  4IKT A;  5E5B A;  3BIQ A;  2GG8 A;  5CE6 A;  3CTZ A;  3FMR A;  4IEC A;  2BH3 A;  3PKE A;  5FCH A;  1W2M A;  2GGB A;  2P99 A;  2BWY A;  4RZY A;  2B3L A;  2BWT A;  4U6C A;  1WKM A;  3TB5 A;  4U75 A;  2MAT A;  2ADU A;  4FLJ A;  5D6E A;  2GU4 A;  3ROR A;  1QXW A;  1R58 A;  4U70 A;  1WN1 A;  4U6W A;  5JI6 A;  2EVC A;  4U73 A;  3FMQ A;  2GG5 A;  3MX6 A;  3MAT A;  4FLI A;  4IU6 A;  4ZNG A;  2B3H A;  4PV4 A;  2EVO A;  1WL9 A;  1C21 A;  4MAT A;  1JAW A;  2BWW A;  2V3X A;  4IDY A;  1YVM A;  1XNZ A;  4IKU A;  4S2R P;  4QR8 A;  4A6W A;  5CDV A;  1O0X A;  2BHA A;  5JHU A;  1CHM A;  2G6P A;  4S01 A;  4IKR A;  1KQ0 A;  2IW2 A;  2V3Y A;  1C24 A;  1C27 A;  4KM3 A;  4IKS A;  2GG3 A;  2BWX A;  2BHD A;  4B28 A;  4PNC A;  3L24 A;  4R60 A;  2GG0 A;  2GZ5 A;  5CLS A;  4ZWO A;  1C23 A;  4JUQ A;  1PV9 A;  3PKD A;  4FO7 A;  1MAT A;  4U6E A;  2OKN A;  2P9A A;  2EA2 A;  5FCF A;  2EVM A;  2GGC A;  2GG7 A;  2Q92 A;  2V6C A;  1KP0 A;  3CB5 A;  4U1B A;  4Z7M A;  1QZY A;  2GG9 A;  2BHB A;  2GTX A;  2BWS A;  4EGE A;  3CB6 A;  4ZWU A;  4FUK A;  4U6Z A;  1XGN A;  4IPA A;  2BWU A;  2BB7 A;  1XGM A;  2P98 A;  1XGS A;  2ZSG A;  5JFR A;  4FO8 A;  4U71 A;  2B3K A;  1B59 A;  3TAV A;  2NQ7 A;  2Q96 A;  3IU9 A;  3IU7 A;  5D6F A;  1Y1N A;  2BHC A;  2GU7 A;  1QXY A;  4OOK A;  4U69 A;  4RGZ 1;  4U76 A;  5CNX A;  3MR1 A;  4RZZ A;  2EA4 A;  3Q6D A;  2DFI A;  4S2T P;  1B6A A;  2V3Z A;  3PKB A;  2Q95 A;  2OAZ A;  4HXX A;  1R5H A;  1C22 A;  2NQ6 A;  2Q93 A;  4A6V A;  3L7G A;  1A16 A;  1QXZ A;  2BWV A;  2Q94 A;  3PKA A;  3RVA A;  2GG2 A;  3PKC A;  1W7V A;  5CDE A;  2GA2 A;  1N51 A;  1WY2 A;  4FLL A;  5CDL A;  1YW7 A;  4ZWP A;  1BN5 A;  4S00 A;  1YW9 A;  1WLR A;  2BN7 A;  2HOW A;  1XGO A;  3FM3 A;  3IG4 A;  2GU5 A;  4FLK A;  1WL6 A;  3S6B A;  1YJ3 A;  1M35 A;  1R5G A;  3BIP A;  4IF7 A;  1KQ9 A;  2Q8K A;  3BIT A;  1BOA A;  3IU8 A;  4U6J A;  4FKC A;  1WBQ A;  2GU6 A;  5CIK A; 
#chains in the Genus database with same CATH homology
 1YW8 A;  3D27 A;  4IKT A;  5E5B A;  3BIQ A;  2GG8 A;  5CE6 A;  3CTZ A;  3FMR A;  4IEC A;  2BH3 A;  3PKE A;  5FCH A;  1W2M A;  2GGB A;  2P99 A;  2BWY A;  4RZY A;  2B3L A;  2BWT A;  4U6C A;  1WKM A;  3TB5 A;  4U75 A;  2MAT A;  2ADU A;  4FLJ A;  5D6E A;  2GU4 A;  3ROR A;  1QXW A;  1R58 A;  4U70 A;  1WN1 A;  4U6W A;  5JI6 A;  2EVC A;  4U73 A;  3FMQ A;  2GG5 A;  3MX6 A;  3MAT A;  4FLI A;  4IU6 A;  4ZNG A;  2B3H A;  4PV4 A;  2EVO A;  1WL9 A;  1C21 A;  4MAT A;  1JAW A;  2BWW A;  2V3X A;  4IDY A;  1YVM A;  1XNZ A;  4IKU A;  4S2R P;  4QR8 A;  4A6W A;  5CDV A;  1O0X A;  2BHA A;  5JHU A;  1CHM A;  2G6P A;  4S01 A;  4IKR A;  1KQ0 A;  2IW2 A;  2V3Y A;  1C24 A;  1C27 A;  4KM3 A;  4IKS A;  2GG3 A;  2BWX A;  2BHD A;  4B28 A;  4PNC A;  3L24 A;  4R60 A;  2GG0 A;  2GZ5 A;  5CLS A;  4ZWO A;  1C23 A;  4JUQ A;  1PV9 A;  3PKD A;  4FO7 A;  1MAT A;  4U6E A;  2OKN A;  2P9A A;  2EA2 A;  5FCF A;  2EVM A;  2GGC A;  2GG7 A;  2Q92 A;  2V6C A;  1KP0 A;  3CB5 A;  4U1B A;  4Z7M A;  1QZY A;  2GG9 A;  2BHB A;  2GTX A;  2BWS A;  4EGE A;  3CB6 A;  4ZWU A;  4FUK A;  4U6Z A;  1XGN A;  4IPA A;  2BWU A;  2BB7 A;  1XGM A;  2P98 A;  1XGS A;  2ZSG A;  5JFR A;  4FO8 A;  4U71 A;  2B3K A;  1B59 A;  3TAV A;  2NQ7 A;  2Q96 A;  3IU9 A;  3IU7 A;  5D6F A;  1Y1N A;  2BHC A;  2GU7 A;  1QXY A;  4OOK A;  4U69 A;  4RGZ 1;  4U76 A;  5CNX A;  3MR1 A;  4RZZ A;  2EA4 A;  3Q6D A;  2DFI A;  4S2T P;  1B6A A;  2V3Z A;  3PKB A;  2Q95 A;  2OAZ A;  4HXX A;  1R5H A;  1C22 A;  2NQ6 A;  2Q93 A;  4A6V A;  3L7G A;  1A16 A;  1QXZ A;  2BWV A;  2Q94 A;  3PKA A;  3RVA A;  2GG2 A;  3PKC A;  1W7V A;  5CDE A;  2GA2 A;  1N51 A;  1WY2 A;  4FLL A;  5CDL A;  1YW7 A;  4ZWP A;  1BN5 A;  4S00 A;  1YW9 A;  1WLR A;  2BN7 A;  2HOW A;  1XGO A;  3FM3 A;  3IG4 A;  2GU5 A;  4FLK A;  1WL6 A;  3S6B A;  1YJ3 A;  1M35 A;  1R5G A;  3BIP A;  4IF7 A;  1KQ9 A;  2Q8K A;  3BIT A;  1BOA A;  3IU8 A;  4U6J A;  4FKC A;  1WBQ A;  2GU6 A;  5CIK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...