3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
2V3ZA 3TAVA 1XGSA 4OOKA 3L7GA 4IKSA 4S2TP 2Q93A 1O0XA 2EVCA 3MATA 3FMRA 1YVMA 2MATA 5CDVA 1JAWA 4FLLA 2BWSA 2B3LA 4FLKA 3RORA 4B28A 1R5GA 4U6JA 2HOWA 5D6FA 4U6ZA 2Q92A 1KQ0A 2EVMA 3BIPA 3IG4A 4IKUA 1WL9A 4IU6A 5JHUA 2P9AA 4FLJA 2Q8KA 1YW7A 4S01A 1M35A 2GTXA 4R60A 1QXWA 2DFIA 3CB5A 4FLIA 5CDEA 5CDLA 4FO8A 1KQ9A 2GG2A 2EVOA 4U6WA 5CIKA 4ZWUA 4IKRA 4S00A 2GG5A 4U69A 3TB5A 1C21A 1WL6A 1W7VA 2BHBA 3PKBA 5FCFA 2EA2A 4IF7A 1XNZA 1YW9A 2BWUA 2BN7A 5JFRA 2Q95A 1R58A 2Q96A 4Z7MA 4U76A 2BB7A 3BITA 4U71A 4U6EA 4A6VA 4RZZA 2GU5A 1N51A 2G6PA 2NQ7A 3CB6A 3PKEA 4FO7A 4IDYA 4FKCA 4HXXA 5FCHA 1C22A 2V3XA 2GG8A 3PKDA 3RVAA 4ZNGA 1QZYA 1WN1A 2B3KA 4RZYA 2GG3A 2GG7A 1XGOA 3IU8A 3FM3A 3MR1A 1R5HA 3PKCA 1WBQA 4U70A 3L24A 2B3HA 4U6CA 1Y1NA 2IW2A 3D27A 2OAZA 5CLSA 1KP0A 4IECA 4PV4A 2GG9A 4IKTA 4A6WA 4RGZ1 2EA4A 3BIQA 3CTZA 1QXYA 1C24A 1WY2A 2BHDA 1WLRA 3PKAA 4JUQA 1B6AA 1QXZA 4IPAA 1C23A 1CHMA 1YJ3A 1XGNA 2ADUA 4U73A 4MATA 2Q94A 1MATA 5CE6A 3IU7A 1C27A 1YW8A 2BHCA 2BWTA 2P98A 5JI6A 1BOAA 2V3YA 4PNCA 3MX6A 2V6CA 4QR8A 1WKMA 4U1BA 5D6EA 3IU9A 2BHAA 3Q6DA 5E5BA 4ZWPA 2BH3A 2BWVA 2BWXA 3S6BA 1W2MA 2GGCA 2GU6A 2GZ5A 5CNXA 4ZWOA 2GA2A 2ZSGA 4U75A 4S2RP 1BN5A 1PV9A 2GU4A 4EGEA 2GGBA 2BWWA 1XGMA 1B59A 2NQ6A 4KM3A 4FUKA 2GU7A 2BWYA 2OKNA 1A16A 2P99A 2GG0A 3FMQA
chains in the Genus database with same CATH superfamily
2V3ZA 3TAVA 1XGSA 4OOKA 3L7GA 4IKSA 4S2TP 2Q93A 1O0XA 2EVCA 3MATA 3FMRA 1YVMA 2MATA 5CDVA 1JAWA 4FLLA 2BWSA 2B3LA 4FLKA 3RORA 4B28A 1R5GA 4U6JA 2HOWA 5D6FA 4U6ZA 2Q92A 1KQ0A 2EVMA 3BIPA 3IG4A 4IKUA 1WL9A 4IU6A 5JHUA 2P9AA 4FLJA 2Q8KA 1YW7A 4S01A 1M35A 2GTXA 4R60A 1QXWA 2DFIA 3CB5A 4FLIA 5CDEA 5CDLA 4FO8A 1KQ9A 2GG2A 2EVOA 4U6WA 5CIKA 4ZWUA 4IKRA 4S00A 2GG5A 4U69A 3TB5A 1C21A 1WL6A 1W7VA 2BHBA 3PKBA 5FCFA 2EA2A 4IF7A 1XNZA 1YW9A 2BWUA 2BN7A 5JFRA 2Q95A 1R58A 2Q96A 4Z7MA 4U76A 2BB7A 3BITA 4U71A 4U6EA 4A6VA 4RZZA 2GU5A 1N51A 2G6PA 2NQ7A 3CB6A 3PKEA 4FO7A 4IDYA 4FKCA 4HXXA 5FCHA 1C22A 2V3XA 2GG8A 3PKDA 3RVAA 4ZNGA 1QZYA 1WN1A 2B3KA 4RZYA 2GG3A 2GG7A 1XGOA 3IU8A 3FM3A 3MR1A 1R5HA 3PKCA 1WBQA 4U70A 3L24A 2B3HA 4U6CA 1Y1NA 2IW2A 3D27A 2OAZA 5CLSA 1KP0A 4IECA 4PV4A 2GG9A 4IKTA 4A6WA 4RGZ1 2EA4A 3BIQA 3CTZA 1QXYA 1C24A 1WY2A 2BHDA 1WLRA 3PKAA 4JUQA 1B6AA 1QXZA 4IPAA 1C23A 1CHMA 1YJ3A 1XGNA 2ADUA 4U73A 4MATA 2Q94A 1MATA 5CE6A 3IU7A 1C27A 1YW8A 2BHCA 2BWTA 2P98A 5JI6A 1BOAA 2V3YA 4PNCA 3MX6A 2V6CA 4QR8A 1WKMA 4U1BA 5D6EA 3IU9A 2BHAA 3Q6DA 5E5BA 4ZWPA 2BH3A 2BWVA 2BWXA 3S6BA 1W2MA 2GGCA 2GU6A 2GZ5A 5CNXA 4ZWOA 2GA2A 2ZSGA 4U75A 4S2RP 1BN5A 1PV9A 2GU4A 4EGEA 2GGBA 2BWWA 1XGMA 1B59A 2NQ6A 4KM3A 4FUKA 2GU7A 2BWYA 2OKNA 1A16A 2P99A 2GG0A 3FMQA
chains in the Genus database with same CATH topology
2V3ZA 3TAVA 1XGSA 4OOKA 3L7GA 4IKSA 4S2TP 2Q93A 1O0XA 2EVCA 3MATA 3FMRA 1YVMA 2MATA 5CDVA 1JAWA 4FLLA 2BWSA 2B3LA 4FLKA 3RORA 4B28A 1R5GA 4U6JA 2HOWA 5D6FA 4U6ZA 2Q92A 1KQ0A 2EVMA 3BIPA 3IG4A 4IKUA 1WL9A 4IU6A 5JHUA 2P9AA 4FLJA 2Q8KA 1YW7A 4S01A 1M35A 2GTXA 4R60A 1QXWA 2DFIA 3CB5A 4FLIA 5CDEA 5CDLA 4FO8A 1KQ9A 2GG2A 2EVOA 4U6WA 5CIKA 4ZWUA 4IKRA 4S00A 2GG5A 4U69A 3TB5A 1C21A 1WL6A 1W7VA 2BHBA 3PKBA 5FCFA 2EA2A 4IF7A 1XNZA 1YW9A 2BWUA 2BN7A 5JFRA 2Q95A 1R58A 2Q96A 4Z7MA 4U76A 2BB7A 3BITA 4U71A 4U6EA 4A6VA 4RZZA 2GU5A 1N51A 2G6PA 2NQ7A 3CB6A 3PKEA 4FO7A 4IDYA 4FKCA 4HXXA 5FCHA 1C22A 2V3XA 2GG8A 3PKDA 3RVAA 4ZNGA 1QZYA 1WN1A 2B3KA 4RZYA 2GG3A 2GG7A 1XGOA 3IU8A 3FM3A 3MR1A 1R5HA 3PKCA 1WBQA 4U70A 3L24A 2B3HA 4U6CA 1Y1NA 2IW2A 3D27A 2OAZA 5CLSA 1KP0A 4IECA 4PV4A 2GG9A 4IKTA 4A6WA 4RGZ1 2EA4A 3BIQA 3CTZA 1QXYA 1C24A 1WY2A 2BHDA 1WLRA 3PKAA 4JUQA 1B6AA 1QXZA 4IPAA 1C23A 1CHMA 1YJ3A 1XGNA 2ADUA 4U73A 4MATA 2Q94A 1MATA 5CE6A 3IU7A 1C27A 1YW8A 2BHCA 2BWTA 2P98A 5JI6A 1BOAA 2V3YA 4PNCA 3MX6A 2V6CA 4QR8A 1WKMA 4U1BA 5D6EA 3IU9A 2BHAA 3Q6DA 5E5BA 4ZWPA 2BH3A 2BWVA 2BWXA 3S6BA 1W2MA 2GGCA 2GU6A 2GZ5A 5CNXA 4ZWOA 2GA2A 2ZSGA 4U75A 4S2RP 1BN5A 1PV9A 2GU4A 4EGEA 2GGBA 2BWWA 1XGMA 1B59A 2NQ6A 4KM3A 4FUKA 2GU7A 2BWYA 2OKNA 1A16A 2P99A 2GG0A 3FMQA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2V3Z A;  3TAV A;  1XGS A;  4OOK A;  3L7G A;  4IKS A;  4S2T P;  2Q93 A;  1O0X A;  2EVC A;  3MAT A;  3FMR A;  1YVM A;  2MAT A;  5CDV A;  1JAW A;  4FLL A;  2BWS A;  2B3L A;  4FLK A;  3ROR A;  4B28 A;  1R5G A;  4U6J A;  2HOW A;  5D6F A;  4U6Z A;  2Q92 A;  1KQ0 A;  2EVM A;  3BIP A;  3IG4 A;  4IKU A;  1WL9 A;  4IU6 A;  5JHU A;  2P9A A;  4FLJ A;  2Q8K A;  1YW7 A;  4S01 A;  1M35 A;  2GTX A;  4R60 A;  1QXW A;  2DFI A;  3CB5 A;  4FLI A;  5CDE A;  5CDL A;  4FO8 A;  1KQ9 A;  2GG2 A;  2EVO A;  4U6W A;  5CIK A;  4ZWU A;  4IKR A;  4S00 A;  2GG5 A;  4U69 A;  3TB5 A;  1C21 A;  1WL6 A;  1W7V A;  2BHB A;  3PKB A;  5FCF A;  2EA2 A;  4IF7 A;  1XNZ A;  1YW9 A;  2BWU A;  2BN7 A;  5JFR A;  2Q95 A;  1R58 A;  2Q96 A;  4Z7M A;  4U76 A;  2BB7 A;  3BIT A;  4U71 A;  4U6E A;  4A6V A;  4RZZ A;  2GU5 A;  1N51 A;  2G6P A;  2NQ7 A;  3CB6 A;  3PKE A;  4FO7 A;  4IDY A;  4FKC A;  4HXX A;  5FCH A;  1C22 A;  2V3X A;  2GG8 A;  3PKD A;  3RVA A;  4ZNG A;  1QZY A;  1WN1 A;  2B3K A;  4RZY A;  2GG3 A;  2GG7 A;  1XGO A;  3IU8 A;  3FM3 A;  3MR1 A;  1R5H A;  3PKC A;  1WBQ A;  4U70 A;  3L24 A;  2B3H A;  4U6C A;  1Y1N A;  2IW2 A;  3D27 A;  2OAZ A;  5CLS A;  1KP0 A;  4IEC A;  4PV4 A;  2GG9 A;  4IKT A;  4A6W A;  4RGZ 1;  2EA4 A;  3BIQ A;  3CTZ A;  1QXY A;  1C24 A;  1WY2 A;  2BHD A;  1WLR A;  3PKA A;  4JUQ A;  1B6A A;  1QXZ A;  4IPA A;  1C23 A;  1CHM A;  1YJ3 A;  1XGN A;  2ADU A;  4U73 A;  4MAT A;  2Q94 A;  1MAT A;  5CE6 A;  3IU7 A;  1C27 A;  1YW8 A;  2BHC A;  2BWT A;  2P98 A;  5JI6 A;  1BOA A;  2V3Y A;  4PNC A;  3MX6 A;  2V6C A;  4QR8 A;  1WKM A;  4U1B A;  5D6E A;  3IU9 A;  2BHA A;  3Q6D A;  5E5B A;  4ZWP A;  2BH3 A;  2BWV A;  2BWX A;  3S6B A;  1W2M A;  2GGC A;  2GU6 A;  2GZ5 A;  5CNX A;  4ZWO A;  2GA2 A;  2ZSG A;  4U75 A;  4S2R P;  1BN5 A;  1PV9 A;  2GU4 A;  4EGE A;  2GGB A;  2BWW A;  1XGM A;  1B59 A;  2NQ6 A;  4KM3 A;  4FUK A;  2GU7 A;  2BWY A;  2OKN A;  1A16 A;  2P99 A;  2GG0 A;  3FMQ A; 
#chains in the Genus database with same CATH topology
 2V3Z A;  3TAV A;  1XGS A;  4OOK A;  3L7G A;  4IKS A;  4S2T P;  2Q93 A;  1O0X A;  2EVC A;  3MAT A;  3FMR A;  1YVM A;  2MAT A;  5CDV A;  1JAW A;  4FLL A;  2BWS A;  2B3L A;  4FLK A;  3ROR A;  4B28 A;  1R5G A;  4U6J A;  2HOW A;  5D6F A;  4U6Z A;  2Q92 A;  1KQ0 A;  2EVM A;  3BIP A;  3IG4 A;  4IKU A;  1WL9 A;  4IU6 A;  5JHU A;  2P9A A;  4FLJ A;  2Q8K A;  1YW7 A;  4S01 A;  1M35 A;  2GTX A;  4R60 A;  1QXW A;  2DFI A;  3CB5 A;  4FLI A;  5CDE A;  5CDL A;  4FO8 A;  1KQ9 A;  2GG2 A;  2EVO A;  4U6W A;  5CIK A;  4ZWU A;  4IKR A;  4S00 A;  2GG5 A;  4U69 A;  3TB5 A;  1C21 A;  1WL6 A;  1W7V A;  2BHB A;  3PKB A;  5FCF A;  2EA2 A;  4IF7 A;  1XNZ A;  1YW9 A;  2BWU A;  2BN7 A;  5JFR A;  2Q95 A;  1R58 A;  2Q96 A;  4Z7M A;  4U76 A;  2BB7 A;  3BIT A;  4U71 A;  4U6E A;  4A6V A;  4RZZ A;  2GU5 A;  1N51 A;  2G6P A;  2NQ7 A;  3CB6 A;  3PKE A;  4FO7 A;  4IDY A;  4FKC A;  4HXX A;  5FCH A;  1C22 A;  2V3X A;  2GG8 A;  3PKD A;  3RVA A;  4ZNG A;  1QZY A;  1WN1 A;  2B3K A;  4RZY A;  2GG3 A;  2GG7 A;  1XGO A;  3IU8 A;  3FM3 A;  3MR1 A;  1R5H A;  3PKC A;  1WBQ A;  4U70 A;  3L24 A;  2B3H A;  4U6C A;  1Y1N A;  2IW2 A;  3D27 A;  2OAZ A;  5CLS A;  1KP0 A;  4IEC A;  4PV4 A;  2GG9 A;  4IKT A;  4A6W A;  4RGZ 1;  2EA4 A;  3BIQ A;  3CTZ A;  1QXY A;  1C24 A;  1WY2 A;  2BHD A;  1WLR A;  3PKA A;  4JUQ A;  1B6A A;  1QXZ A;  4IPA A;  1C23 A;  1CHM A;  1YJ3 A;  1XGN A;  2ADU A;  4U73 A;  4MAT A;  2Q94 A;  1MAT A;  5CE6 A;  3IU7 A;  1C27 A;  1YW8 A;  2BHC A;  2BWT A;  2P98 A;  5JI6 A;  1BOA A;  2V3Y A;  4PNC A;  3MX6 A;  2V6C A;  4QR8 A;  1WKM A;  4U1B A;  5D6E A;  3IU9 A;  2BHA A;  3Q6D A;  5E5B A;  4ZWP A;  2BH3 A;  2BWV A;  2BWX A;  3S6B A;  1W2M A;  2GGC A;  2GU6 A;  2GZ5 A;  5CNX A;  4ZWO A;  2GA2 A;  2ZSG A;  4U75 A;  4S2R P;  1BN5 A;  1PV9 A;  2GU4 A;  4EGE A;  2GGB A;  2BWW A;  1XGM A;  1B59 A;  2NQ6 A;  4KM3 A;  4FUK A;  2GU7 A;  2BWY A;  2OKN A;  1A16 A;  2P99 A;  2GG0 A;  3FMQ A; 
#chains in the Genus database with same CATH homology
 2V3Z A;  3TAV A;  1XGS A;  4OOK A;  3L7G A;  4IKS A;  4S2T P;  2Q93 A;  1O0X A;  2EVC A;  3MAT A;  3FMR A;  1YVM A;  2MAT A;  5CDV A;  1JAW A;  4FLL A;  2BWS A;  2B3L A;  4FLK A;  3ROR A;  4B28 A;  1R5G A;  4U6J A;  2HOW A;  5D6F A;  4U6Z A;  2Q92 A;  1KQ0 A;  2EVM A;  3BIP A;  3IG4 A;  4IKU A;  1WL9 A;  4IU6 A;  5JHU A;  2P9A A;  4FLJ A;  2Q8K A;  1YW7 A;  4S01 A;  1M35 A;  2GTX A;  4R60 A;  1QXW A;  2DFI A;  3CB5 A;  4FLI A;  5CDE A;  5CDL A;  4FO8 A;  1KQ9 A;  2GG2 A;  2EVO A;  4U6W A;  5CIK A;  4ZWU A;  4IKR A;  4S00 A;  2GG5 A;  4U69 A;  3TB5 A;  1C21 A;  1WL6 A;  1W7V A;  2BHB A;  3PKB A;  5FCF A;  2EA2 A;  4IF7 A;  1XNZ A;  1YW9 A;  2BWU A;  2BN7 A;  5JFR A;  2Q95 A;  1R58 A;  2Q96 A;  4Z7M A;  4U76 A;  2BB7 A;  3BIT A;  4U71 A;  4U6E A;  4A6V A;  4RZZ A;  2GU5 A;  1N51 A;  2G6P A;  2NQ7 A;  3CB6 A;  3PKE A;  4FO7 A;  4IDY A;  4FKC A;  4HXX A;  5FCH A;  1C22 A;  2V3X A;  2GG8 A;  3PKD A;  3RVA A;  4ZNG A;  1QZY A;  1WN1 A;  2B3K A;  4RZY A;  2GG3 A;  2GG7 A;  1XGO A;  3IU8 A;  3FM3 A;  3MR1 A;  1R5H A;  3PKC A;  1WBQ A;  4U70 A;  3L24 A;  2B3H A;  4U6C A;  1Y1N A;  2IW2 A;  3D27 A;  2OAZ A;  5CLS A;  1KP0 A;  4IEC A;  4PV4 A;  2GG9 A;  4IKT A;  4A6W A;  4RGZ 1;  2EA4 A;  3BIQ A;  3CTZ A;  1QXY A;  1C24 A;  1WY2 A;  2BHD A;  1WLR A;  3PKA A;  4JUQ A;  1B6A A;  1QXZ A;  4IPA A;  1C23 A;  1CHM A;  1YJ3 A;  1XGN A;  2ADU A;  4U73 A;  4MAT A;  2Q94 A;  1MAT A;  5CE6 A;  3IU7 A;  1C27 A;  1YW8 A;  2BHC A;  2BWT A;  2P98 A;  5JI6 A;  1BOA A;  2V3Y A;  4PNC A;  3MX6 A;  2V6C A;  4QR8 A;  1WKM A;  4U1B A;  5D6E A;  3IU9 A;  2BHA A;  3Q6D A;  5E5B A;  4ZWP A;  2BH3 A;  2BWV A;  2BWX A;  3S6B A;  1W2M A;  2GGC A;  2GU6 A;  2GZ5 A;  5CNX A;  4ZWO A;  2GA2 A;  2ZSG A;  4U75 A;  4S2R P;  1BN5 A;  1PV9 A;  2GU4 A;  4EGE A;  2GGB A;  2BWW A;  1XGM A;  1B59 A;  2NQ6 A;  4KM3 A;  4FUK A;  2GU7 A;  2BWY A;  2OKN A;  1A16 A;  2P99 A;  2GG0 A;  3FMQ A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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