3IU9A

M. tuberculosis methionine aminopeptidase with ni inhibitor t07
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
total genus 89
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu9A01
1XGMA 2EVCA 1QXYA 4IDYA 3L7GA 3BIQA 2HOWA 5JI6A 1KP0A 2BB7A 3IU8A 3MATA 3PKBA 4IU6A 4RGZ1 2B3HA 3TB5A 1M35A 4FO8A 3D27A 3MR1A 3IU9A 2GG0A 5CE6A 4IKTA 2Q96A 3MX6A 1WN1A 2GU5A 2P98A 1WL9A 5CIKA 2ZSGA 1C27A 2EVOA 1PV9A 2GG3A 3L24A 2V3YA 3Q6DA 2BWUA 2BHCA 2GG9A 3FM3A 3FMQA 3PKCA 1QZYA 1W7VA 4R60A 2B3KA 1C23A 1WKMA 1XGNA 2IW2A 2B3LA 1R58A 2OAZA 5JFRA 2BWTA 1XGSA 2ADUA 4S2RP 1QXWA 2MATA 5D6FA 1BOAA 4U6CA 2Q94A 4IF7A 2OKNA 3IU7A 4U6ZA 4ZWPA 2EVMA 4OOKA 1Y1NA 4U1BA 4B28A 4FUKA 1BN5A 2BHAA 4ZWUA 4A6WA 4U75A 1C22A 2GTXA 4EGEA 5CDVA 3IG4A 4RZYA 4Z7MA 4IPAA 1XNZA 3PKDA 2BN7A 2BHDA 2BWYA 4IKUA 5CLSA 4A6VA 1WL6A 2GA2A 1A16A 2G6PA 2GU6A 5CNXA 1JAWA 2BWSA 1KQ0A 4FLLA 1WBQA 2Q92A 3S6BA 1R5GA 2GG2A 4RZZA 1C24A 4PNCA 1CHMA 2NQ6A 2BWVA 3BIPA 4U71A 1B59A 2EA4A 4FLKA 1YW9A 4FKCA 4KM3A 3RORA 1N51A 1WY2A 5D6EA 4U6WA 2GG8A 3CB6A 4PV4A 4U73A 1YJ3A 2P9AA 2GZ5A 3RVAA 1YW7A 2GGCA 4HXXA 5E5BA 1WLRA 1YVMA 5JHUA 1YW8A 5CDEA 3PKAA 5FCFA 2Q8KA 4IKSA 4QR8A 2GGBA 4U69A 4IKRA 1R5HA 2BWWA 4U6JA 4ZWOA 2NQ7A 1B6AA 4FLJA 3TAVA 2GG5A 2BHBA 4S00A 1KQ9A 1QXZA 2GG7A 2V3ZA 5FCHA 4JUQA 3CB5A 2V6CA 2BH3A 1O0XA 4S2TP 3FMRA 4FO7A 3BITA 4U6EA 2V3XA 2P99A 4MATA 2DFIA 4U76A 2GU4A 4FLIA 3PKEA 2Q93A 4S01A 2Q95A 2GU7A 1W2MA 5CDLA 1XGOA 4U70A 2EA2A 4IECA 4ZNGA 1MATA 1C21A 3CTZA 2BWXA
chains in the Genus database with same CATH superfamily
1XGMA 2EVCA 1QXYA 4IDYA 3L7GA 3BIQA 2HOWA 5JI6A 1KP0A 2BB7A 3IU8A 3MATA 3PKBA 4IU6A 4RGZ1 2B3HA 3TB5A 1M35A 4FO8A 3D27A 3MR1A 3IU9A 2GG0A 5CE6A 4IKTA 2Q96A 3MX6A 1WN1A 2GU5A 2P98A 1WL9A 5CIKA 2ZSGA 1C27A 2EVOA 1PV9A 2GG3A 3L24A 2V3YA 3Q6DA 2BWUA 2BHCA 2GG9A 3FM3A 3FMQA 3PKCA 1QZYA 1W7VA 4R60A 2B3KA 1C23A 1WKMA 1XGNA 2IW2A 2B3LA 1R58A 2OAZA 5JFRA 2BWTA 1XGSA 2ADUA 4S2RP 1QXWA 2MATA 5D6FA 1BOAA 4U6CA 2Q94A 4IF7A 2OKNA 3IU7A 4U6ZA 4ZWPA 2EVMA 4OOKA 1Y1NA 4U1BA 4B28A 4FUKA 1BN5A 2BHAA 4ZWUA 4A6WA 4U75A 1C22A 2GTXA 4EGEA 5CDVA 3IG4A 4RZYA 4Z7MA 4IPAA 1XNZA 3PKDA 2BN7A 2BHDA 2BWYA 4IKUA 5CLSA 4A6VA 1WL6A 2GA2A 1A16A 2G6PA 2GU6A 5CNXA 1JAWA 2BWSA 1KQ0A 4FLLA 1WBQA 2Q92A 3S6BA 1R5GA 2GG2A 4RZZA 1C24A 4PNCA 1CHMA 2NQ6A 2BWVA 3BIPA 4U71A 1B59A 2EA4A 4FLKA 1YW9A 4FKCA 4KM3A 3RORA 1N51A 1WY2A 5D6EA 4U6WA 2GG8A 3CB6A 4PV4A 4U73A 1YJ3A 2P9AA 2GZ5A 3RVAA 1YW7A 2GGCA 4HXXA 5E5BA 1WLRA 1YVMA 5JHUA 1YW8A 5CDEA 3PKAA 5FCFA 2Q8KA 4IKSA 4QR8A 2GGBA 4U69A 4IKRA 1R5HA 2BWWA 4U6JA 4ZWOA 2NQ7A 1B6AA 4FLJA 3TAVA 2GG5A 2BHBA 4S00A 1KQ9A 1QXZA 2GG7A 2V3ZA 5FCHA 4JUQA 3CB5A 2V6CA 2BH3A 1O0XA 4S2TP 3FMRA 4FO7A 3BITA 4U6EA 2V3XA 2P99A 4MATA 2DFIA 4U76A 2GU4A 4FLIA 3PKEA 2Q93A 4S01A 2Q95A 2GU7A 1W2MA 5CDLA 1XGOA 4U70A 2EA2A 4IECA 4ZNGA 1MATA 1C21A 3CTZA 2BWXA
chains in the Genus database with same CATH topology
1XGMA 2EVCA 1QXYA 4IDYA 3L7GA 3BIQA 2HOWA 5JI6A 1KP0A 2BB7A 3IU8A 3MATA 3PKBA 4IU6A 4RGZ1 2B3HA 3TB5A 1M35A 4FO8A 3D27A 3MR1A 3IU9A 2GG0A 5CE6A 4IKTA 2Q96A 3MX6A 1WN1A 2GU5A 2P98A 1WL9A 5CIKA 2ZSGA 1C27A 2EVOA 1PV9A 2GG3A 3L24A 2V3YA 3Q6DA 2BWUA 2BHCA 2GG9A 3FM3A 3FMQA 3PKCA 1QZYA 1W7VA 4R60A 2B3KA 1C23A 1WKMA 1XGNA 2IW2A 2B3LA 1R58A 2OAZA 5JFRA 2BWTA 1XGSA 2ADUA 4S2RP 1QXWA 2MATA 5D6FA 1BOAA 4U6CA 2Q94A 4IF7A 2OKNA 3IU7A 4U6ZA 4ZWPA 2EVMA 4OOKA 1Y1NA 4U1BA 4B28A 4FUKA 1BN5A 2BHAA 4ZWUA 4A6WA 4U75A 1C22A 2GTXA 4EGEA 5CDVA 3IG4A 4RZYA 4Z7MA 4IPAA 1XNZA 3PKDA 2BN7A 2BHDA 2BWYA 4IKUA 5CLSA 4A6VA 1WL6A 2GA2A 1A16A 2G6PA 2GU6A 5CNXA 1JAWA 2BWSA 1KQ0A 4FLLA 1WBQA 2Q92A 3S6BA 1R5GA 2GG2A 4RZZA 1C24A 4PNCA 1CHMA 2NQ6A 2BWVA 3BIPA 4U71A 1B59A 2EA4A 4FLKA 1YW9A 4FKCA 4KM3A 3RORA 1N51A 1WY2A 5D6EA 4U6WA 2GG8A 3CB6A 4PV4A 4U73A 1YJ3A 2P9AA 2GZ5A 3RVAA 1YW7A 2GGCA 4HXXA 5E5BA 1WLRA 1YVMA 5JHUA 1YW8A 5CDEA 3PKAA 5FCFA 2Q8KA 4IKSA 4QR8A 2GGBA 4U69A 4IKRA 1R5HA 2BWWA 4U6JA 4ZWOA 2NQ7A 1B6AA 4FLJA 3TAVA 2GG5A 2BHBA 4S00A 1KQ9A 1QXZA 2GG7A 2V3ZA 5FCHA 4JUQA 3CB5A 2V6CA 2BH3A 1O0XA 4S2TP 3FMRA 4FO7A 3BITA 4U6EA 2V3XA 2P99A 4MATA 2DFIA 4U76A 2GU4A 4FLIA 3PKEA 2Q93A 4S01A 2Q95A 2GU7A 1W2MA 5CDLA 1XGOA 4U70A 2EA2A 4IECA 4ZNGA 1MATA 1C21A 3CTZA 2BWXA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1XGM A;  2EVC A;  1QXY A;  4IDY A;  3L7G A;  3BIQ A;  2HOW A;  5JI6 A;  1KP0 A;  2BB7 A;  3IU8 A;  3MAT A;  3PKB A;  4IU6 A;  4RGZ 1;  2B3H A;  3TB5 A;  1M35 A;  4FO8 A;  3D27 A;  3MR1 A;  3IU9 A;  2GG0 A;  5CE6 A;  4IKT A;  2Q96 A;  3MX6 A;  1WN1 A;  2GU5 A;  2P98 A;  1WL9 A;  5CIK A;  2ZSG A;  1C27 A;  2EVO A;  1PV9 A;  2GG3 A;  3L24 A;  2V3Y A;  3Q6D A;  2BWU A;  2BHC A;  2GG9 A;  3FM3 A;  3FMQ A;  3PKC A;  1QZY A;  1W7V A;  4R60 A;  2B3K A;  1C23 A;  1WKM A;  1XGN A;  2IW2 A;  2B3L A;  1R58 A;  2OAZ A;  5JFR A;  2BWT A;  1XGS A;  2ADU A;  4S2R P;  1QXW A;  2MAT A;  5D6F A;  1BOA A;  4U6C A;  2Q94 A;  4IF7 A;  2OKN A;  3IU7 A;  4U6Z A;  4ZWP A;  2EVM A;  4OOK A;  1Y1N A;  4U1B A;  4B28 A;  4FUK A;  1BN5 A;  2BHA A;  4ZWU A;  4A6W A;  4U75 A;  1C22 A;  2GTX A;  4EGE A;  5CDV A;  3IG4 A;  4RZY A;  4Z7M A;  4IPA A;  1XNZ A;  3PKD A;  2BN7 A;  2BHD A;  2BWY A;  4IKU A;  5CLS A;  4A6V A;  1WL6 A;  2GA2 A;  1A16 A;  2G6P A;  2GU6 A;  5CNX A;  1JAW A;  2BWS A;  1KQ0 A;  4FLL A;  1WBQ A;  2Q92 A;  3S6B A;  1R5G A;  2GG2 A;  4RZZ A;  1C24 A;  4PNC A;  1CHM A;  2NQ6 A;  2BWV A;  3BIP A;  4U71 A;  1B59 A;  2EA4 A;  4FLK A;  1YW9 A;  4FKC A;  4KM3 A;  3ROR A;  1N51 A;  1WY2 A;  5D6E A;  4U6W A;  2GG8 A;  3CB6 A;  4PV4 A;  4U73 A;  1YJ3 A;  2P9A A;  2GZ5 A;  3RVA A;  1YW7 A;  2GGC A;  4HXX A;  5E5B A;  1WLR A;  1YVM A;  5JHU A;  1YW8 A;  5CDE A;  3PKA A;  5FCF A;  2Q8K A;  4IKS A;  4QR8 A;  2GGB A;  4U69 A;  4IKR A;  1R5H A;  2BWW A;  4U6J A;  4ZWO A;  2NQ7 A;  1B6A A;  4FLJ A;  3TAV A;  2GG5 A;  2BHB A;  4S00 A;  1KQ9 A;  1QXZ A;  2GG7 A;  2V3Z A;  5FCH A;  4JUQ A;  3CB5 A;  2V6C A;  2BH3 A;  1O0X A;  4S2T P;  3FMR A;  4FO7 A;  3BIT A;  4U6E A;  2V3X A;  2P99 A;  4MAT A;  2DFI A;  4U76 A;  2GU4 A;  4FLI A;  3PKE A;  2Q93 A;  4S01 A;  2Q95 A;  2GU7 A;  1W2M A;  5CDL A;  1XGO A;  4U70 A;  2EA2 A;  4IEC A;  4ZNG A;  1MAT A;  1C21 A;  3CTZ A;  2BWX A; 
#chains in the Genus database with same CATH topology
 1XGM A;  2EVC A;  1QXY A;  4IDY A;  3L7G A;  3BIQ A;  2HOW A;  5JI6 A;  1KP0 A;  2BB7 A;  3IU8 A;  3MAT A;  3PKB A;  4IU6 A;  4RGZ 1;  2B3H A;  3TB5 A;  1M35 A;  4FO8 A;  3D27 A;  3MR1 A;  3IU9 A;  2GG0 A;  5CE6 A;  4IKT A;  2Q96 A;  3MX6 A;  1WN1 A;  2GU5 A;  2P98 A;  1WL9 A;  5CIK A;  2ZSG A;  1C27 A;  2EVO A;  1PV9 A;  2GG3 A;  3L24 A;  2V3Y A;  3Q6D A;  2BWU A;  2BHC A;  2GG9 A;  3FM3 A;  3FMQ A;  3PKC A;  1QZY A;  1W7V A;  4R60 A;  2B3K A;  1C23 A;  1WKM A;  1XGN A;  2IW2 A;  2B3L A;  1R58 A;  2OAZ A;  5JFR A;  2BWT A;  1XGS A;  2ADU A;  4S2R P;  1QXW A;  2MAT A;  5D6F A;  1BOA A;  4U6C A;  2Q94 A;  4IF7 A;  2OKN A;  3IU7 A;  4U6Z A;  4ZWP A;  2EVM A;  4OOK A;  1Y1N A;  4U1B A;  4B28 A;  4FUK A;  1BN5 A;  2BHA A;  4ZWU A;  4A6W A;  4U75 A;  1C22 A;  2GTX A;  4EGE A;  5CDV A;  3IG4 A;  4RZY A;  4Z7M A;  4IPA A;  1XNZ A;  3PKD A;  2BN7 A;  2BHD A;  2BWY A;  4IKU A;  5CLS A;  4A6V A;  1WL6 A;  2GA2 A;  1A16 A;  2G6P A;  2GU6 A;  5CNX A;  1JAW A;  2BWS A;  1KQ0 A;  4FLL A;  1WBQ A;  2Q92 A;  3S6B A;  1R5G A;  2GG2 A;  4RZZ A;  1C24 A;  4PNC A;  1CHM A;  2NQ6 A;  2BWV A;  3BIP A;  4U71 A;  1B59 A;  2EA4 A;  4FLK A;  1YW9 A;  4FKC A;  4KM3 A;  3ROR A;  1N51 A;  1WY2 A;  5D6E A;  4U6W A;  2GG8 A;  3CB6 A;  4PV4 A;  4U73 A;  1YJ3 A;  2P9A A;  2GZ5 A;  3RVA A;  1YW7 A;  2GGC A;  4HXX A;  5E5B A;  1WLR A;  1YVM A;  5JHU A;  1YW8 A;  5CDE A;  3PKA A;  5FCF A;  2Q8K A;  4IKS A;  4QR8 A;  2GGB A;  4U69 A;  4IKR A;  1R5H A;  2BWW A;  4U6J A;  4ZWO A;  2NQ7 A;  1B6A A;  4FLJ A;  3TAV A;  2GG5 A;  2BHB A;  4S00 A;  1KQ9 A;  1QXZ A;  2GG7 A;  2V3Z A;  5FCH A;  4JUQ A;  3CB5 A;  2V6C A;  2BH3 A;  1O0X A;  4S2T P;  3FMR A;  4FO7 A;  3BIT A;  4U6E A;  2V3X A;  2P99 A;  4MAT A;  2DFI A;  4U76 A;  2GU4 A;  4FLI A;  3PKE A;  2Q93 A;  4S01 A;  2Q95 A;  2GU7 A;  1W2M A;  5CDL A;  1XGO A;  4U70 A;  2EA2 A;  4IEC A;  4ZNG A;  1MAT A;  1C21 A;  3CTZ A;  2BWX A; 
#chains in the Genus database with same CATH homology
 1XGM A;  2EVC A;  1QXY A;  4IDY A;  3L7G A;  3BIQ A;  2HOW A;  5JI6 A;  1KP0 A;  2BB7 A;  3IU8 A;  3MAT A;  3PKB A;  4IU6 A;  4RGZ 1;  2B3H A;  3TB5 A;  1M35 A;  4FO8 A;  3D27 A;  3MR1 A;  3IU9 A;  2GG0 A;  5CE6 A;  4IKT A;  2Q96 A;  3MX6 A;  1WN1 A;  2GU5 A;  2P98 A;  1WL9 A;  5CIK A;  2ZSG A;  1C27 A;  2EVO A;  1PV9 A;  2GG3 A;  3L24 A;  2V3Y A;  3Q6D A;  2BWU A;  2BHC A;  2GG9 A;  3FM3 A;  3FMQ A;  3PKC A;  1QZY A;  1W7V A;  4R60 A;  2B3K A;  1C23 A;  1WKM A;  1XGN A;  2IW2 A;  2B3L A;  1R58 A;  2OAZ A;  5JFR A;  2BWT A;  1XGS A;  2ADU A;  4S2R P;  1QXW A;  2MAT A;  5D6F A;  1BOA A;  4U6C A;  2Q94 A;  4IF7 A;  2OKN A;  3IU7 A;  4U6Z A;  4ZWP A;  2EVM A;  4OOK A;  1Y1N A;  4U1B A;  4B28 A;  4FUK A;  1BN5 A;  2BHA A;  4ZWU A;  4A6W A;  4U75 A;  1C22 A;  2GTX A;  4EGE A;  5CDV A;  3IG4 A;  4RZY A;  4Z7M A;  4IPA A;  1XNZ A;  3PKD A;  2BN7 A;  2BHD A;  2BWY A;  4IKU A;  5CLS A;  4A6V A;  1WL6 A;  2GA2 A;  1A16 A;  2G6P A;  2GU6 A;  5CNX A;  1JAW A;  2BWS A;  1KQ0 A;  4FLL A;  1WBQ A;  2Q92 A;  3S6B A;  1R5G A;  2GG2 A;  4RZZ A;  1C24 A;  4PNC A;  1CHM A;  2NQ6 A;  2BWV A;  3BIP A;  4U71 A;  1B59 A;  2EA4 A;  4FLK A;  1YW9 A;  4FKC A;  4KM3 A;  3ROR A;  1N51 A;  1WY2 A;  5D6E A;  4U6W A;  2GG8 A;  3CB6 A;  4PV4 A;  4U73 A;  1YJ3 A;  2P9A A;  2GZ5 A;  3RVA A;  1YW7 A;  2GGC A;  4HXX A;  5E5B A;  1WLR A;  1YVM A;  5JHU A;  1YW8 A;  5CDE A;  3PKA A;  5FCF A;  2Q8K A;  4IKS A;  4QR8 A;  2GGB A;  4U69 A;  4IKR A;  1R5H A;  2BWW A;  4U6J A;  4ZWO A;  2NQ7 A;  1B6A A;  4FLJ A;  3TAV A;  2GG5 A;  2BHB A;  4S00 A;  1KQ9 A;  1QXZ A;  2GG7 A;  2V3Z A;  5FCH A;  4JUQ A;  3CB5 A;  2V6C A;  2BH3 A;  1O0X A;  4S2T P;  3FMR A;  4FO7 A;  3BIT A;  4U6E A;  2V3X A;  2P99 A;  4MAT A;  2DFI A;  4U76 A;  2GU4 A;  4FLI A;  3PKE A;  2Q93 A;  4S01 A;  2Q95 A;  2GU7 A;  1W2M A;  5CDL A;  1XGO A;  4U70 A;  2EA2 A;  4IEC A;  4ZNG A;  1MAT A;  1C21 A;  3CTZ A;  2BWX A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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