3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
2GU5A 1QXWA 2BWTA 4U6WA 5JFRA 4KM3A 2BHBA 3BIPA 4IU6A 4ZWUA 2BWYA 2B3LA 4EGEA 5CNXA 4ZWOA 1BOAA 2ZSGA 3BITA 4A6WA 3IU7A 2GGBA 1XGOA 1QXYA 4IKTA 3MR1A 4S2TP 5CDVA 1WKMA 3Q6DA 4A6VA 5CDEA 2P99A 5CLSA 1YW7A 4U70A 4U6EA 1W7VA 1XGSA 5JHUA 4S01A 1YW8A 1R5HA 2Q92A 4R60A 5CDLA 5FCFA 2EVOA 2GG8A 2EVCA 1XGMA 3BIQA 1KP0A 2BWVA 2BHAA 2OAZA 4ZNGA 4FUKA 1Y1NA 5CIKA 5D6EA 1N51A 4FO7A 4IKRA 1WBQA 1YVMA 1W2MA 2Q8KA 1C24A 3CB5A 4PNCA 2BH3A 3IU9A 2GU4A 2GZ5A 4IDYA 1KQ9A 4FLIA 1WL9A 2NQ6A 4FLJA 2GGCA 1BN5A 2Q93A 4HXXA 4S2RP 1B6AA 4PV4A 3L24A 4RGZ1 4ZWPA 5JI6A 1XGNA 2Q95A 2P9AA 4Z7MA 2B3HA 2ADUA 1R58A 5D6FA 2GG3A 1WLRA 2V3XA 4FKCA 2V3ZA 4IECA 4IF7A 1O0XA 4U76A 2Q96A 1JAWA 1C22A 1XNZA 3CTZA 1C21A 3TAVA 3FMQA 3PKAA 2GG0A 1M35A 4IPAA 2GTXA 3MX6A 4B28A 2GU6A 2HOWA 2NQ7A 4FLLA 1B59A 3S6BA 1YJ3A 1WY2A 3FMRA 2IW2A 4FLKA 4RZZA 1YW9A 1C23A 2BHDA 2V6CA 3L7GA 3PKDA 1C27A 4U6JA 2BB7A 2BWWA 2GG5A 2BWUA 1A16A 4U1BA 5E5BA 4QR8A 2BN7A 2BWSA 4MATA 1WL6A 2GA2A 2OKNA 2P98A 2Q94A 4JUQA 4RZYA 1R5GA 2BHCA 2EA2A 4S00A 2GG2A 1PV9A 2EA4A 3RORA 1KQ0A 4U6CA 1WN1A 2DFIA 4IKSA 4OOKA 4U75A 2B3KA 2GG7A 3FM3A 1CHMA 3D27A 2GU7A 4U6ZA 3TB5A 3PKEA 2G6PA 4U73A 3CB6A 3PKBA 2V3YA 4IKUA 4U71A 2GG9A 1MATA 3IG4A 1QZYA 2BWXA 2EVMA 2MATA 3IU8A 5FCHA 3RVAA 3PKCA 5CE6A 4U69A 1QXZA 4FO8A 3MATA
chains in the Genus database with same CATH superfamily
2GU5A 1QXWA 2BWTA 4U6WA 5JFRA 4KM3A 2BHBA 3BIPA 4IU6A 4ZWUA 2BWYA 2B3LA 4EGEA 5CNXA 4ZWOA 1BOAA 2ZSGA 3BITA 4A6WA 3IU7A 2GGBA 1XGOA 1QXYA 4IKTA 3MR1A 4S2TP 5CDVA 1WKMA 3Q6DA 4A6VA 5CDEA 2P99A 5CLSA 1YW7A 4U70A 4U6EA 1W7VA 1XGSA 5JHUA 4S01A 1YW8A 1R5HA 2Q92A 4R60A 5CDLA 5FCFA 2EVOA 2GG8A 2EVCA 1XGMA 3BIQA 1KP0A 2BWVA 2BHAA 2OAZA 4ZNGA 4FUKA 1Y1NA 5CIKA 5D6EA 1N51A 4FO7A 4IKRA 1WBQA 1YVMA 1W2MA 2Q8KA 1C24A 3CB5A 4PNCA 2BH3A 3IU9A 2GU4A 2GZ5A 4IDYA 1KQ9A 4FLIA 1WL9A 2NQ6A 4FLJA 2GGCA 1BN5A 2Q93A 4HXXA 4S2RP 1B6AA 4PV4A 3L24A 4RGZ1 4ZWPA 5JI6A 1XGNA 2Q95A 2P9AA 4Z7MA 2B3HA 2ADUA 1R58A 5D6FA 2GG3A 1WLRA 2V3XA 4FKCA 2V3ZA 4IECA 4IF7A 1O0XA 4U76A 2Q96A 1JAWA 1C22A 1XNZA 3CTZA 1C21A 3TAVA 3FMQA 3PKAA 2GG0A 1M35A 4IPAA 2GTXA 3MX6A 4B28A 2GU6A 2HOWA 2NQ7A 4FLLA 1B59A 3S6BA 1YJ3A 1WY2A 3FMRA 2IW2A 4FLKA 4RZZA 1YW9A 1C23A 2BHDA 2V6CA 3L7GA 3PKDA 1C27A 4U6JA 2BB7A 2BWWA 2GG5A 2BWUA 1A16A 4U1BA 5E5BA 4QR8A 2BN7A 2BWSA 4MATA 1WL6A 2GA2A 2OKNA 2P98A 2Q94A 4JUQA 4RZYA 1R5GA 2BHCA 2EA2A 4S00A 2GG2A 1PV9A 2EA4A 3RORA 1KQ0A 4U6CA 1WN1A 2DFIA 4IKSA 4OOKA 4U75A 2B3KA 2GG7A 3FM3A 1CHMA 3D27A 2GU7A 4U6ZA 3TB5A 3PKEA 2G6PA 4U73A 3CB6A 3PKBA 2V3YA 4IKUA 4U71A 2GG9A 1MATA 3IG4A 1QZYA 2BWXA 2EVMA 2MATA 3IU8A 5FCHA 3RVAA 3PKCA 5CE6A 4U69A 1QXZA 4FO8A 3MATA
chains in the Genus database with same CATH topology
2GU5A 1QXWA 2BWTA 4U6WA 5JFRA 4KM3A 2BHBA 3BIPA 4IU6A 4ZWUA 2BWYA 2B3LA 4EGEA 5CNXA 4ZWOA 1BOAA 2ZSGA 3BITA 4A6WA 3IU7A 2GGBA 1XGOA 1QXYA 4IKTA 3MR1A 4S2TP 5CDVA 1WKMA 3Q6DA 4A6VA 5CDEA 2P99A 5CLSA 1YW7A 4U70A 4U6EA 1W7VA 1XGSA 5JHUA 4S01A 1YW8A 1R5HA 2Q92A 4R60A 5CDLA 5FCFA 2EVOA 2GG8A 2EVCA 1XGMA 3BIQA 1KP0A 2BWVA 2BHAA 2OAZA 4ZNGA 4FUKA 1Y1NA 5CIKA 5D6EA 1N51A 4FO7A 4IKRA 1WBQA 1YVMA 1W2MA 2Q8KA 1C24A 3CB5A 4PNCA 2BH3A 3IU9A 2GU4A 2GZ5A 4IDYA 1KQ9A 4FLIA 1WL9A 2NQ6A 4FLJA 2GGCA 1BN5A 2Q93A 4HXXA 4S2RP 1B6AA 4PV4A 3L24A 4RGZ1 4ZWPA 5JI6A 1XGNA 2Q95A 2P9AA 4Z7MA 2B3HA 2ADUA 1R58A 5D6FA 2GG3A 1WLRA 2V3XA 4FKCA 2V3ZA 4IECA 4IF7A 1O0XA 4U76A 2Q96A 1JAWA 1C22A 1XNZA 3CTZA 1C21A 3TAVA 3FMQA 3PKAA 2GG0A 1M35A 4IPAA 2GTXA 3MX6A 4B28A 2GU6A 2HOWA 2NQ7A 4FLLA 1B59A 3S6BA 1YJ3A 1WY2A 3FMRA 2IW2A 4FLKA 4RZZA 1YW9A 1C23A 2BHDA 2V6CA 3L7GA 3PKDA 1C27A 4U6JA 2BB7A 2BWWA 2GG5A 2BWUA 1A16A 4U1BA 5E5BA 4QR8A 2BN7A 2BWSA 4MATA 1WL6A 2GA2A 2OKNA 2P98A 2Q94A 4JUQA 4RZYA 1R5GA 2BHCA 2EA2A 4S00A 2GG2A 1PV9A 2EA4A 3RORA 1KQ0A 4U6CA 1WN1A 2DFIA 4IKSA 4OOKA 4U75A 2B3KA 2GG7A 3FM3A 1CHMA 3D27A 2GU7A 4U6ZA 3TB5A 3PKEA 2G6PA 4U73A 3CB6A 3PKBA 2V3YA 4IKUA 4U71A 2GG9A 1MATA 3IG4A 1QZYA 2BWXA 2EVMA 2MATA 3IU8A 5FCHA 3RVAA 3PKCA 5CE6A 4U69A 1QXZA 4FO8A 3MATA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GU5 A;  1QXW A;  2BWT A;  4U6W A;  5JFR A;  4KM3 A;  2BHB A;  3BIP A;  4IU6 A;  4ZWU A;  2BWY A;  2B3L A;  4EGE A;  5CNX A;  4ZWO A;  1BOA A;  2ZSG A;  3BIT A;  4A6W A;  3IU7 A;  2GGB A;  1XGO A;  1QXY A;  4IKT A;  3MR1 A;  4S2T P;  5CDV A;  1WKM A;  3Q6D A;  4A6V A;  5CDE A;  2P99 A;  5CLS A;  1YW7 A;  4U70 A;  4U6E A;  1W7V A;  1XGS A;  5JHU A;  4S01 A;  1YW8 A;  1R5H A;  2Q92 A;  4R60 A;  5CDL A;  5FCF A;  2EVO A;  2GG8 A;  2EVC A;  1XGM A;  3BIQ A;  1KP0 A;  2BWV A;  2BHA A;  2OAZ A;  4ZNG A;  4FUK A;  1Y1N A;  5CIK A;  5D6E A;  1N51 A;  4FO7 A;  4IKR A;  1WBQ A;  1YVM A;  1W2M A;  2Q8K A;  1C24 A;  3CB5 A;  4PNC A;  2BH3 A;  3IU9 A;  2GU4 A;  2GZ5 A;  4IDY A;  1KQ9 A;  4FLI A;  1WL9 A;  2NQ6 A;  4FLJ A;  2GGC A;  1BN5 A;  2Q93 A;  4HXX A;  4S2R P;  1B6A A;  4PV4 A;  3L24 A;  4RGZ 1;  4ZWP A;  5JI6 A;  1XGN A;  2Q95 A;  2P9A A;  4Z7M A;  2B3H A;  2ADU A;  1R58 A;  5D6F A;  2GG3 A;  1WLR A;  2V3X A;  4FKC A;  2V3Z A;  4IEC A;  4IF7 A;  1O0X A;  4U76 A;  2Q96 A;  1JAW A;  1C22 A;  1XNZ A;  3CTZ A;  1C21 A;  3TAV A;  3FMQ A;  3PKA A;  2GG0 A;  1M35 A;  4IPA A;  2GTX A;  3MX6 A;  4B28 A;  2GU6 A;  2HOW A;  2NQ7 A;  4FLL A;  1B59 A;  3S6B A;  1YJ3 A;  1WY2 A;  3FMR A;  2IW2 A;  4FLK A;  4RZZ A;  1YW9 A;  1C23 A;  2BHD A;  2V6C A;  3L7G A;  3PKD A;  1C27 A;  4U6J A;  2BB7 A;  2BWW A;  2GG5 A;  2BWU A;  1A16 A;  4U1B A;  5E5B A;  4QR8 A;  2BN7 A;  2BWS A;  4MAT A;  1WL6 A;  2GA2 A;  2OKN A;  2P98 A;  2Q94 A;  4JUQ A;  4RZY A;  1R5G A;  2BHC A;  2EA2 A;  4S00 A;  2GG2 A;  1PV9 A;  2EA4 A;  3ROR A;  1KQ0 A;  4U6C A;  1WN1 A;  2DFI A;  4IKS A;  4OOK A;  4U75 A;  2B3K A;  2GG7 A;  3FM3 A;  1CHM A;  3D27 A;  2GU7 A;  4U6Z A;  3TB5 A;  3PKE A;  2G6P A;  4U73 A;  3CB6 A;  3PKB A;  2V3Y A;  4IKU A;  4U71 A;  2GG9 A;  1MAT A;  3IG4 A;  1QZY A;  2BWX A;  2EVM A;  2MAT A;  3IU8 A;  5FCH A;  3RVA A;  3PKC A;  5CE6 A;  4U69 A;  1QXZ A;  4FO8 A;  3MAT A; 
#chains in the Genus database with same CATH topology
 2GU5 A;  1QXW A;  2BWT A;  4U6W A;  5JFR A;  4KM3 A;  2BHB A;  3BIP A;  4IU6 A;  4ZWU A;  2BWY A;  2B3L A;  4EGE A;  5CNX A;  4ZWO A;  1BOA A;  2ZSG A;  3BIT A;  4A6W A;  3IU7 A;  2GGB A;  1XGO A;  1QXY A;  4IKT A;  3MR1 A;  4S2T P;  5CDV A;  1WKM A;  3Q6D A;  4A6V A;  5CDE A;  2P99 A;  5CLS A;  1YW7 A;  4U70 A;  4U6E A;  1W7V A;  1XGS A;  5JHU A;  4S01 A;  1YW8 A;  1R5H A;  2Q92 A;  4R60 A;  5CDL A;  5FCF A;  2EVO A;  2GG8 A;  2EVC A;  1XGM A;  3BIQ A;  1KP0 A;  2BWV A;  2BHA A;  2OAZ A;  4ZNG A;  4FUK A;  1Y1N A;  5CIK A;  5D6E A;  1N51 A;  4FO7 A;  4IKR A;  1WBQ A;  1YVM A;  1W2M A;  2Q8K A;  1C24 A;  3CB5 A;  4PNC A;  2BH3 A;  3IU9 A;  2GU4 A;  2GZ5 A;  4IDY A;  1KQ9 A;  4FLI A;  1WL9 A;  2NQ6 A;  4FLJ A;  2GGC A;  1BN5 A;  2Q93 A;  4HXX A;  4S2R P;  1B6A A;  4PV4 A;  3L24 A;  4RGZ 1;  4ZWP A;  5JI6 A;  1XGN A;  2Q95 A;  2P9A A;  4Z7M A;  2B3H A;  2ADU A;  1R58 A;  5D6F A;  2GG3 A;  1WLR A;  2V3X A;  4FKC A;  2V3Z A;  4IEC A;  4IF7 A;  1O0X A;  4U76 A;  2Q96 A;  1JAW A;  1C22 A;  1XNZ A;  3CTZ A;  1C21 A;  3TAV A;  3FMQ A;  3PKA A;  2GG0 A;  1M35 A;  4IPA A;  2GTX A;  3MX6 A;  4B28 A;  2GU6 A;  2HOW A;  2NQ7 A;  4FLL A;  1B59 A;  3S6B A;  1YJ3 A;  1WY2 A;  3FMR A;  2IW2 A;  4FLK A;  4RZZ A;  1YW9 A;  1C23 A;  2BHD A;  2V6C A;  3L7G A;  3PKD A;  1C27 A;  4U6J A;  2BB7 A;  2BWW A;  2GG5 A;  2BWU A;  1A16 A;  4U1B A;  5E5B A;  4QR8 A;  2BN7 A;  2BWS A;  4MAT A;  1WL6 A;  2GA2 A;  2OKN A;  2P98 A;  2Q94 A;  4JUQ A;  4RZY A;  1R5G A;  2BHC A;  2EA2 A;  4S00 A;  2GG2 A;  1PV9 A;  2EA4 A;  3ROR A;  1KQ0 A;  4U6C A;  1WN1 A;  2DFI A;  4IKS A;  4OOK A;  4U75 A;  2B3K A;  2GG7 A;  3FM3 A;  1CHM A;  3D27 A;  2GU7 A;  4U6Z A;  3TB5 A;  3PKE A;  2G6P A;  4U73 A;  3CB6 A;  3PKB A;  2V3Y A;  4IKU A;  4U71 A;  2GG9 A;  1MAT A;  3IG4 A;  1QZY A;  2BWX A;  2EVM A;  2MAT A;  3IU8 A;  5FCH A;  3RVA A;  3PKC A;  5CE6 A;  4U69 A;  1QXZ A;  4FO8 A;  3MAT A; 
#chains in the Genus database with same CATH homology
 2GU5 A;  1QXW A;  2BWT A;  4U6W A;  5JFR A;  4KM3 A;  2BHB A;  3BIP A;  4IU6 A;  4ZWU A;  2BWY A;  2B3L A;  4EGE A;  5CNX A;  4ZWO A;  1BOA A;  2ZSG A;  3BIT A;  4A6W A;  3IU7 A;  2GGB A;  1XGO A;  1QXY A;  4IKT A;  3MR1 A;  4S2T P;  5CDV A;  1WKM A;  3Q6D A;  4A6V A;  5CDE A;  2P99 A;  5CLS A;  1YW7 A;  4U70 A;  4U6E A;  1W7V A;  1XGS A;  5JHU A;  4S01 A;  1YW8 A;  1R5H A;  2Q92 A;  4R60 A;  5CDL A;  5FCF A;  2EVO A;  2GG8 A;  2EVC A;  1XGM A;  3BIQ A;  1KP0 A;  2BWV A;  2BHA A;  2OAZ A;  4ZNG A;  4FUK A;  1Y1N A;  5CIK A;  5D6E A;  1N51 A;  4FO7 A;  4IKR A;  1WBQ A;  1YVM A;  1W2M A;  2Q8K A;  1C24 A;  3CB5 A;  4PNC A;  2BH3 A;  3IU9 A;  2GU4 A;  2GZ5 A;  4IDY A;  1KQ9 A;  4FLI A;  1WL9 A;  2NQ6 A;  4FLJ A;  2GGC A;  1BN5 A;  2Q93 A;  4HXX A;  4S2R P;  1B6A A;  4PV4 A;  3L24 A;  4RGZ 1;  4ZWP A;  5JI6 A;  1XGN A;  2Q95 A;  2P9A A;  4Z7M A;  2B3H A;  2ADU A;  1R58 A;  5D6F A;  2GG3 A;  1WLR A;  2V3X A;  4FKC A;  2V3Z A;  4IEC A;  4IF7 A;  1O0X A;  4U76 A;  2Q96 A;  1JAW A;  1C22 A;  1XNZ A;  3CTZ A;  1C21 A;  3TAV A;  3FMQ A;  3PKA A;  2GG0 A;  1M35 A;  4IPA A;  2GTX A;  3MX6 A;  4B28 A;  2GU6 A;  2HOW A;  2NQ7 A;  4FLL A;  1B59 A;  3S6B A;  1YJ3 A;  1WY2 A;  3FMR A;  2IW2 A;  4FLK A;  4RZZ A;  1YW9 A;  1C23 A;  2BHD A;  2V6C A;  3L7G A;  3PKD A;  1C27 A;  4U6J A;  2BB7 A;  2BWW A;  2GG5 A;  2BWU A;  1A16 A;  4U1B A;  5E5B A;  4QR8 A;  2BN7 A;  2BWS A;  4MAT A;  1WL6 A;  2GA2 A;  2OKN A;  2P98 A;  2Q94 A;  4JUQ A;  4RZY A;  1R5G A;  2BHC A;  2EA2 A;  4S00 A;  2GG2 A;  1PV9 A;  2EA4 A;  3ROR A;  1KQ0 A;  4U6C A;  1WN1 A;  2DFI A;  4IKS A;  4OOK A;  4U75 A;  2B3K A;  2GG7 A;  3FM3 A;  1CHM A;  3D27 A;  2GU7 A;  4U6Z A;  3TB5 A;  3PKE A;  2G6P A;  4U73 A;  3CB6 A;  3PKB A;  2V3Y A;  4IKU A;  4U71 A;  2GG9 A;  1MAT A;  3IG4 A;  1QZY A;  2BWX A;  2EVM A;  2MAT A;  3IU8 A;  5FCH A;  3RVA A;  3PKC A;  5CE6 A;  4U69 A;  1QXZ A;  4FO8 A;  3MAT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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