3PKAA

M. tuberculosis metap with bengamide analog y02, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkaA01
5CLSA 1QZYA 2NQ6A 4IKTA 2BWVA 1CHMA 2GGBA 3MX6A 4FKCA 4FO8A 5CIKA 1XGMA 4FLJA 3CTZA 4KM3A 5JHUA 3IU8A 2BN7A 1WY2A 3IU7A 1C27A 5FCFA 1XGSA 2V3ZA 4EGEA 4U1BA 2V3YA 2OKNA 3RVAA 1WL9A 2EVCA 5JFRA 3TAVA 1JAWA 1MATA 4IKUA 2BHAA 2GZ5A 1W7VA 4PV4A 2NQ7A 4PNCA 5CDVA 4R60A 2GG9A 4U69A 5E5BA 2EVOA 1O0XA 1PV9A 2GU4A 1N51A 3PKEA 1XNZA 5CNXA 1YVMA 1B59A 1YJ3A 5D6FA 3L7GA 3S6BA 1A16A 4IDYA 3BIPA 2GG8A 2MATA 2V6CA 4U6WA 4U75A 2BHCA 3MR1A 4FO7A 1KQ0A 2P98A 4A6VA 3BIQA 1C22A 4IPAA 2OAZA 4ZNGA 4U71A 4RZYA 1YW9A 2EA2A 4U6ZA 4IF7A 4FLKA 4HXXA 3CB5A 1W2MA 3FMQA 1BN5A 5JI6A 4IU6A 1XGOA 3FMRA 4JUQA 4IKRA 2B3HA 2P99A 2Q8KA 2BWSA 1KQ9A 2GU6A 4FLIA 2BB7A 1Y1NA 2BH3A 2GA2A 4IECA 3IG4A 4ZWOA 4QR8A 3TB5A 1QXYA 2ZSGA 4IKSA 4FLLA 2Q95A 2DFIA 3CB6A 5CDLA 2BHDA 4FUKA 2G6PA 2BWUA 2GG7A 2GTXA 2GU7A 2Q92A 4MATA 2GU5A 3FM3A 4U6JA 1BOAA 2BWYA 2B3LA 4U73A 4S00A 2B3KA 3PKAA 2BWXA 4OOKA 1WBQA 4S2TP 4ZWUA 4Z7MA 1B6AA 3D27A 2EA4A 2GG0A 3PKDA 1R58A 3BITA 1C23A 4U6EA 1C24A 3L24A 2BWWA 5FCHA 4U76A 1C21A 4S01A 2IW2A 1WL6A 4RGZ1 3PKBA 2GG5A 1KP0A 1YW8A 2BWTA 3IU9A 1QXWA 3MATA 4ZWPA 2Q94A 1WN1A 1WLRA 1XGNA 4U70A 2GG3A 5D6EA 4A6WA 1YW7A 2ADUA 1QXZA 1R5GA 2EVMA 2BHBA 4S2RP 2GG2A 3PKCA 4U6CA 5CE6A 3RORA 5CDEA 4RZZA 1WKMA 2P9AA 4B28A 3Q6DA 2Q96A 2HOWA 2Q93A 1R5HA 2GGCA 2V3XA 1M35A
chains in the Genus database with same CATH superfamily
5CLSA 1QZYA 2NQ6A 4IKTA 2BWVA 1CHMA 2GGBA 3MX6A 4FKCA 4FO8A 5CIKA 1XGMA 4FLJA 3CTZA 4KM3A 5JHUA 3IU8A 2BN7A 1WY2A 3IU7A 1C27A 5FCFA 1XGSA 2V3ZA 4EGEA 4U1BA 2V3YA 2OKNA 3RVAA 1WL9A 2EVCA 5JFRA 3TAVA 1JAWA 1MATA 4IKUA 2BHAA 2GZ5A 1W7VA 4PV4A 2NQ7A 4PNCA 5CDVA 4R60A 2GG9A 4U69A 5E5BA 2EVOA 1O0XA 1PV9A 2GU4A 1N51A 3PKEA 1XNZA 5CNXA 1YVMA 1B59A 1YJ3A 5D6FA 3L7GA 3S6BA 1A16A 4IDYA 3BIPA 2GG8A 2MATA 2V6CA 4U6WA 4U75A 2BHCA 3MR1A 4FO7A 1KQ0A 2P98A 4A6VA 3BIQA 1C22A 4IPAA 2OAZA 4ZNGA 4U71A 4RZYA 1YW9A 2EA2A 4U6ZA 4IF7A 4FLKA 4HXXA 3CB5A 1W2MA 3FMQA 1BN5A 5JI6A 4IU6A 1XGOA 3FMRA 4JUQA 4IKRA 2B3HA 2P99A 2Q8KA 2BWSA 1KQ9A 2GU6A 4FLIA 2BB7A 1Y1NA 2BH3A 2GA2A 4IECA 3IG4A 4ZWOA 4QR8A 3TB5A 1QXYA 2ZSGA 4IKSA 4FLLA 2Q95A 2DFIA 3CB6A 5CDLA 2BHDA 4FUKA 2G6PA 2BWUA 2GG7A 2GTXA 2GU7A 2Q92A 4MATA 2GU5A 3FM3A 4U6JA 1BOAA 2BWYA 2B3LA 4U73A 4S00A 2B3KA 3PKAA 2BWXA 4OOKA 1WBQA 4S2TP 4ZWUA 4Z7MA 1B6AA 3D27A 2EA4A 2GG0A 3PKDA 1R58A 3BITA 1C23A 4U6EA 1C24A 3L24A 2BWWA 5FCHA 4U76A 1C21A 4S01A 2IW2A 1WL6A 4RGZ1 3PKBA 2GG5A 1KP0A 1YW8A 2BWTA 3IU9A 1QXWA 3MATA 4ZWPA 2Q94A 1WN1A 1WLRA 1XGNA 4U70A 2GG3A 5D6EA 4A6WA 1YW7A 2ADUA 1QXZA 1R5GA 2EVMA 2BHBA 4S2RP 2GG2A 3PKCA 4U6CA 5CE6A 3RORA 5CDEA 4RZZA 1WKMA 2P9AA 4B28A 3Q6DA 2Q96A 2HOWA 2Q93A 1R5HA 2GGCA 2V3XA 1M35A
chains in the Genus database with same CATH topology
5CLSA 1QZYA 2NQ6A 4IKTA 2BWVA 1CHMA 2GGBA 3MX6A 4FKCA 4FO8A 5CIKA 1XGMA 4FLJA 3CTZA 4KM3A 5JHUA 3IU8A 2BN7A 1WY2A 3IU7A 1C27A 5FCFA 1XGSA 2V3ZA 4EGEA 4U1BA 2V3YA 2OKNA 3RVAA 1WL9A 2EVCA 5JFRA 3TAVA 1JAWA 1MATA 4IKUA 2BHAA 2GZ5A 1W7VA 4PV4A 2NQ7A 4PNCA 5CDVA 4R60A 2GG9A 4U69A 5E5BA 2EVOA 1O0XA 1PV9A 2GU4A 1N51A 3PKEA 1XNZA 5CNXA 1YVMA 1B59A 1YJ3A 5D6FA 3L7GA 3S6BA 1A16A 4IDYA 3BIPA 2GG8A 2MATA 2V6CA 4U6WA 4U75A 2BHCA 3MR1A 4FO7A 1KQ0A 2P98A 4A6VA 3BIQA 1C22A 4IPAA 2OAZA 4ZNGA 4U71A 4RZYA 1YW9A 2EA2A 4U6ZA 4IF7A 4FLKA 4HXXA 3CB5A 1W2MA 3FMQA 1BN5A 5JI6A 4IU6A 1XGOA 3FMRA 4JUQA 4IKRA 2B3HA 2P99A 2Q8KA 2BWSA 1KQ9A 2GU6A 4FLIA 2BB7A 1Y1NA 2BH3A 2GA2A 4IECA 3IG4A 4ZWOA 4QR8A 3TB5A 1QXYA 2ZSGA 4IKSA 4FLLA 2Q95A 2DFIA 3CB6A 5CDLA 2BHDA 4FUKA 2G6PA 2BWUA 2GG7A 2GTXA 2GU7A 2Q92A 4MATA 2GU5A 3FM3A 4U6JA 1BOAA 2BWYA 2B3LA 4U73A 4S00A 2B3KA 3PKAA 2BWXA 4OOKA 1WBQA 4S2TP 4ZWUA 4Z7MA 1B6AA 3D27A 2EA4A 2GG0A 3PKDA 1R58A 3BITA 1C23A 4U6EA 1C24A 3L24A 2BWWA 5FCHA 4U76A 1C21A 4S01A 2IW2A 1WL6A 4RGZ1 3PKBA 2GG5A 1KP0A 1YW8A 2BWTA 3IU9A 1QXWA 3MATA 4ZWPA 2Q94A 1WN1A 1WLRA 1XGNA 4U70A 2GG3A 5D6EA 4A6WA 1YW7A 2ADUA 1QXZA 1R5GA 2EVMA 2BHBA 4S2RP 2GG2A 3PKCA 4U6CA 5CE6A 3RORA 5CDEA 4RZZA 1WKMA 2P9AA 4B28A 3Q6DA 2Q96A 2HOWA 2Q93A 1R5HA 2GGCA 2V3XA 1M35A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CLS A;  1QZY A;  2NQ6 A;  4IKT A;  2BWV A;  1CHM A;  2GGB A;  3MX6 A;  4FKC A;  4FO8 A;  5CIK A;  1XGM A;  4FLJ A;  3CTZ A;  4KM3 A;  5JHU A;  3IU8 A;  2BN7 A;  1WY2 A;  3IU7 A;  1C27 A;  5FCF A;  1XGS A;  2V3Z A;  4EGE A;  4U1B A;  2V3Y A;  2OKN A;  3RVA A;  1WL9 A;  2EVC A;  5JFR A;  3TAV A;  1JAW A;  1MAT A;  4IKU A;  2BHA A;  2GZ5 A;  1W7V A;  4PV4 A;  2NQ7 A;  4PNC A;  5CDV A;  4R60 A;  2GG9 A;  4U69 A;  5E5B A;  2EVO A;  1O0X A;  1PV9 A;  2GU4 A;  1N51 A;  3PKE A;  1XNZ A;  5CNX A;  1YVM A;  1B59 A;  1YJ3 A;  5D6F A;  3L7G A;  3S6B A;  1A16 A;  4IDY A;  3BIP A;  2GG8 A;  2MAT A;  2V6C A;  4U6W A;  4U75 A;  2BHC A;  3MR1 A;  4FO7 A;  1KQ0 A;  2P98 A;  4A6V A;  3BIQ A;  1C22 A;  4IPA A;  2OAZ A;  4ZNG A;  4U71 A;  4RZY A;  1YW9 A;  2EA2 A;  4U6Z A;  4IF7 A;  4FLK A;  4HXX A;  3CB5 A;  1W2M A;  3FMQ A;  1BN5 A;  5JI6 A;  4IU6 A;  1XGO A;  3FMR A;  4JUQ A;  4IKR A;  2B3H A;  2P99 A;  2Q8K A;  2BWS A;  1KQ9 A;  2GU6 A;  4FLI A;  2BB7 A;  1Y1N A;  2BH3 A;  2GA2 A;  4IEC A;  3IG4 A;  4ZWO A;  4QR8 A;  3TB5 A;  1QXY A;  2ZSG A;  4IKS A;  4FLL A;  2Q95 A;  2DFI A;  3CB6 A;  5CDL A;  2BHD A;  4FUK A;  2G6P A;  2BWU A;  2GG7 A;  2GTX A;  2GU7 A;  2Q92 A;  4MAT A;  2GU5 A;  3FM3 A;  4U6J A;  1BOA A;  2BWY A;  2B3L A;  4U73 A;  4S00 A;  2B3K A;  3PKA A;  2BWX A;  4OOK A;  1WBQ A;  4S2T P;  4ZWU A;  4Z7M A;  1B6A A;  3D27 A;  2EA4 A;  2GG0 A;  3PKD A;  1R58 A;  3BIT A;  1C23 A;  4U6E A;  1C24 A;  3L24 A;  2BWW A;  5FCH A;  4U76 A;  1C21 A;  4S01 A;  2IW2 A;  1WL6 A;  4RGZ 1;  3PKB A;  2GG5 A;  1KP0 A;  1YW8 A;  2BWT A;  3IU9 A;  1QXW A;  3MAT A;  4ZWP A;  2Q94 A;  1WN1 A;  1WLR A;  1XGN A;  4U70 A;  2GG3 A;  5D6E A;  4A6W A;  1YW7 A;  2ADU A;  1QXZ A;  1R5G A;  2EVM A;  2BHB A;  4S2R P;  2GG2 A;  3PKC A;  4U6C A;  5CE6 A;  3ROR A;  5CDE A;  4RZZ A;  1WKM A;  2P9A A;  4B28 A;  3Q6D A;  2Q96 A;  2HOW A;  2Q93 A;  1R5H A;  2GGC A;  2V3X A;  1M35 A; 
#chains in the Genus database with same CATH topology
 5CLS A;  1QZY A;  2NQ6 A;  4IKT A;  2BWV A;  1CHM A;  2GGB A;  3MX6 A;  4FKC A;  4FO8 A;  5CIK A;  1XGM A;  4FLJ A;  3CTZ A;  4KM3 A;  5JHU A;  3IU8 A;  2BN7 A;  1WY2 A;  3IU7 A;  1C27 A;  5FCF A;  1XGS A;  2V3Z A;  4EGE A;  4U1B A;  2V3Y A;  2OKN A;  3RVA A;  1WL9 A;  2EVC A;  5JFR A;  3TAV A;  1JAW A;  1MAT A;  4IKU A;  2BHA A;  2GZ5 A;  1W7V A;  4PV4 A;  2NQ7 A;  4PNC A;  5CDV A;  4R60 A;  2GG9 A;  4U69 A;  5E5B A;  2EVO A;  1O0X A;  1PV9 A;  2GU4 A;  1N51 A;  3PKE A;  1XNZ A;  5CNX A;  1YVM A;  1B59 A;  1YJ3 A;  5D6F A;  3L7G A;  3S6B A;  1A16 A;  4IDY A;  3BIP A;  2GG8 A;  2MAT A;  2V6C A;  4U6W A;  4U75 A;  2BHC A;  3MR1 A;  4FO7 A;  1KQ0 A;  2P98 A;  4A6V A;  3BIQ A;  1C22 A;  4IPA A;  2OAZ A;  4ZNG A;  4U71 A;  4RZY A;  1YW9 A;  2EA2 A;  4U6Z A;  4IF7 A;  4FLK A;  4HXX A;  3CB5 A;  1W2M A;  3FMQ A;  1BN5 A;  5JI6 A;  4IU6 A;  1XGO A;  3FMR A;  4JUQ A;  4IKR A;  2B3H A;  2P99 A;  2Q8K A;  2BWS A;  1KQ9 A;  2GU6 A;  4FLI A;  2BB7 A;  1Y1N A;  2BH3 A;  2GA2 A;  4IEC A;  3IG4 A;  4ZWO A;  4QR8 A;  3TB5 A;  1QXY A;  2ZSG A;  4IKS A;  4FLL A;  2Q95 A;  2DFI A;  3CB6 A;  5CDL A;  2BHD A;  4FUK A;  2G6P A;  2BWU A;  2GG7 A;  2GTX A;  2GU7 A;  2Q92 A;  4MAT A;  2GU5 A;  3FM3 A;  4U6J A;  1BOA A;  2BWY A;  2B3L A;  4U73 A;  4S00 A;  2B3K A;  3PKA A;  2BWX A;  4OOK A;  1WBQ A;  4S2T P;  4ZWU A;  4Z7M A;  1B6A A;  3D27 A;  2EA4 A;  2GG0 A;  3PKD A;  1R58 A;  3BIT A;  1C23 A;  4U6E A;  1C24 A;  3L24 A;  2BWW A;  5FCH A;  4U76 A;  1C21 A;  4S01 A;  2IW2 A;  1WL6 A;  4RGZ 1;  3PKB A;  2GG5 A;  1KP0 A;  1YW8 A;  2BWT A;  3IU9 A;  1QXW A;  3MAT A;  4ZWP A;  2Q94 A;  1WN1 A;  1WLR A;  1XGN A;  4U70 A;  2GG3 A;  5D6E A;  4A6W A;  1YW7 A;  2ADU A;  1QXZ A;  1R5G A;  2EVM A;  2BHB A;  4S2R P;  2GG2 A;  3PKC A;  4U6C A;  5CE6 A;  3ROR A;  5CDE A;  4RZZ A;  1WKM A;  2P9A A;  4B28 A;  3Q6D A;  2Q96 A;  2HOW A;  2Q93 A;  1R5H A;  2GGC A;  2V3X A;  1M35 A; 
#chains in the Genus database with same CATH homology
 5CLS A;  1QZY A;  2NQ6 A;  4IKT A;  2BWV A;  1CHM A;  2GGB A;  3MX6 A;  4FKC A;  4FO8 A;  5CIK A;  1XGM A;  4FLJ A;  3CTZ A;  4KM3 A;  5JHU A;  3IU8 A;  2BN7 A;  1WY2 A;  3IU7 A;  1C27 A;  5FCF A;  1XGS A;  2V3Z A;  4EGE A;  4U1B A;  2V3Y A;  2OKN A;  3RVA A;  1WL9 A;  2EVC A;  5JFR A;  3TAV A;  1JAW A;  1MAT A;  4IKU A;  2BHA A;  2GZ5 A;  1W7V A;  4PV4 A;  2NQ7 A;  4PNC A;  5CDV A;  4R60 A;  2GG9 A;  4U69 A;  5E5B A;  2EVO A;  1O0X A;  1PV9 A;  2GU4 A;  1N51 A;  3PKE A;  1XNZ A;  5CNX A;  1YVM A;  1B59 A;  1YJ3 A;  5D6F A;  3L7G A;  3S6B A;  1A16 A;  4IDY A;  3BIP A;  2GG8 A;  2MAT A;  2V6C A;  4U6W A;  4U75 A;  2BHC A;  3MR1 A;  4FO7 A;  1KQ0 A;  2P98 A;  4A6V A;  3BIQ A;  1C22 A;  4IPA A;  2OAZ A;  4ZNG A;  4U71 A;  4RZY A;  1YW9 A;  2EA2 A;  4U6Z A;  4IF7 A;  4FLK A;  4HXX A;  3CB5 A;  1W2M A;  3FMQ A;  1BN5 A;  5JI6 A;  4IU6 A;  1XGO A;  3FMR A;  4JUQ A;  4IKR A;  2B3H A;  2P99 A;  2Q8K A;  2BWS A;  1KQ9 A;  2GU6 A;  4FLI A;  2BB7 A;  1Y1N A;  2BH3 A;  2GA2 A;  4IEC A;  3IG4 A;  4ZWO A;  4QR8 A;  3TB5 A;  1QXY A;  2ZSG A;  4IKS A;  4FLL A;  2Q95 A;  2DFI A;  3CB6 A;  5CDL A;  2BHD A;  4FUK A;  2G6P A;  2BWU A;  2GG7 A;  2GTX A;  2GU7 A;  2Q92 A;  4MAT A;  2GU5 A;  3FM3 A;  4U6J A;  1BOA A;  2BWY A;  2B3L A;  4U73 A;  4S00 A;  2B3K A;  3PKA A;  2BWX A;  4OOK A;  1WBQ A;  4S2T P;  4ZWU A;  4Z7M A;  1B6A A;  3D27 A;  2EA4 A;  2GG0 A;  3PKD A;  1R58 A;  3BIT A;  1C23 A;  4U6E A;  1C24 A;  3L24 A;  2BWW A;  5FCH A;  4U76 A;  1C21 A;  4S01 A;  2IW2 A;  1WL6 A;  4RGZ 1;  3PKB A;  2GG5 A;  1KP0 A;  1YW8 A;  2BWT A;  3IU9 A;  1QXW A;  3MAT A;  4ZWP A;  2Q94 A;  1WN1 A;  1WLR A;  1XGN A;  4U70 A;  2GG3 A;  5D6E A;  4A6W A;  1YW7 A;  2ADU A;  1QXZ A;  1R5G A;  2EVM A;  2BHB A;  4S2R P;  2GG2 A;  3PKC A;  4U6C A;  5CE6 A;  3ROR A;  5CDE A;  4RZZ A;  1WKM A;  2P9A A;  4B28 A;  3Q6D A;  2Q96 A;  2HOW A;  2Q93 A;  1R5H A;  2GGC A;  2V3X A;  1M35 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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