3TB5A

Crystal structure of the enterococcus faecalis methionine aminopeptidase apo form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
254
structure length
254
Chain Sequence
MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAQIGYEGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAISDSCWSYVVGESTPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDFVGHGIGPTIHESPMIPHYGEAGKGLRLKEGMVITIEPMVNTGTWRMKMDPNGWTAYTEDGGLSCQYEHSLAITKEGPRILTSQGEELTY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Enterococcus faecalis
total genus 87
structure length 254
sequence length 254
chains with identical sequence B, C
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tb5A00
2Q96A 2GA2A 5E5BA 2V3ZA 3RORA 2GG5A 2BWSA 2MATA 4FLKA 4U73A 4S2TP 2OKNA 2V3YA 2GGBA 4ZNGA 3MATA 3TAVA 1BOAA 4FLJA 4ZWUA 2V6CA 1KQ0A 2DFIA 2Q94A 4U69A 2GG9A 4U70A 4FLIA 3FMRA 3BITA 2OAZA 4FKCA 1Y1NA 2NQ7A 1JAWA 4KM3A 4PV4A 4EGEA 5CNXA 4ZWPA 1C24A 2GU5A 1O0XA 1W7VA 4IKTA 4HXXA 2B3HA 5D6EA 1XGNA 4IF7A 1C23A 3IU7A 3TB5A 2Q93A 3D27A 2BWWA 3PKDA 1KP0A 4QR8A 3RVAA 1QXYA 1WY2A 3MR1A 3CB5A 2BWXA 4FO7A 2GZ5A 2BWVA 2HOWA 2BHDA 3CTZA 3IG4A 2ADUA 1XGSA 2ZSGA 1A16A 2EVOA 1WN1A 1QXWA 1B6AA 2Q95A 3Q6DA 4IDYA 1WBQA 4JUQA 5CE6A 1KQ9A 5CIKA 1YW7A 3FM3A 2BB7A 3IU8A 1YW9A 4S01A 3L7GA 1PV9A 1XNZA 1C21A 1MATA 1WL6A 4U71A 4FO8A 5JHUA 2BWYA 4IKRA 2BWTA 4S00A 2GG3A 2P98A 4MATA 1C27A 2P99A 1XGMA 4A6WA 2GG2A 4RZYA 1YVMA 4U6EA 2GTXA 3FMQA 2GG7A 4IKSA 2GG0A 2BWUA 2B3KA 4FLLA 2BH3A 3CB6A 4OOKA 4S2RP 3PKAA 1WKMA 5JFRA 3L24A 1YW8A 1N51A 4RGZ1 2G6PA 3PKEA 1R5HA 2GG8A 2EA4A 3PKCA 1B59A 3BIQA 2NQ6A 3S6BA 5CDEA 4Z7MA 4RZZA 4B28A 1R58A 1BN5A 2EVMA 5CDLA 1WLRA 1QXZA 1M35A 4U6WA 3PKBA 2EA2A 3MX6A 4IECA 2BN7A 1XGOA 4PNCA 1YJ3A 4ZWOA 4U6CA 4U6ZA 1W2MA 2BHAA 1WL9A 2GGCA 1CHMA 1C22A 1R5GA 4FUKA 4IU6A 4IPAA 4R60A 5D6FA 2GU6A 2Q92A 4A6VA 5JI6A 1QZYA 4U6JA 4U75A 2GU4A 2GU7A 2P9AA 4U1BA 5FCFA 2BHCA 2IW2A 3IU9A 2B3LA 2BHBA 2V3XA 4IKUA 5FCHA 5CLSA 5CDVA 2Q8KA 4U76A 2EVCA 3BIPA
chains in the Genus database with same CATH superfamily
2Q96A 2GA2A 5E5BA 2V3ZA 3RORA 2GG5A 2BWSA 2MATA 4FLKA 4U73A 4S2TP 2OKNA 2V3YA 2GGBA 4ZNGA 3MATA 3TAVA 1BOAA 4FLJA 4ZWUA 2V6CA 1KQ0A 2DFIA 2Q94A 4U69A 2GG9A 4U70A 4FLIA 3FMRA 3BITA 2OAZA 4FKCA 1Y1NA 2NQ7A 1JAWA 4KM3A 4PV4A 4EGEA 5CNXA 4ZWPA 1C24A 2GU5A 1O0XA 1W7VA 4IKTA 4HXXA 2B3HA 5D6EA 1XGNA 4IF7A 1C23A 3IU7A 3TB5A 2Q93A 3D27A 2BWWA 3PKDA 1KP0A 4QR8A 3RVAA 1QXYA 1WY2A 3MR1A 3CB5A 2BWXA 4FO7A 2GZ5A 2BWVA 2HOWA 2BHDA 3CTZA 3IG4A 2ADUA 1XGSA 2ZSGA 1A16A 2EVOA 1WN1A 1QXWA 1B6AA 2Q95A 3Q6DA 4IDYA 1WBQA 4JUQA 5CE6A 1KQ9A 5CIKA 1YW7A 3FM3A 2BB7A 3IU8A 1YW9A 4S01A 3L7GA 1PV9A 1XNZA 1C21A 1MATA 1WL6A 4U71A 4FO8A 5JHUA 2BWYA 4IKRA 2BWTA 4S00A 2GG3A 2P98A 4MATA 1C27A 2P99A 1XGMA 4A6WA 2GG2A 4RZYA 1YVMA 4U6EA 2GTXA 3FMQA 2GG7A 4IKSA 2GG0A 2BWUA 2B3KA 4FLLA 2BH3A 3CB6A 4OOKA 4S2RP 3PKAA 1WKMA 5JFRA 3L24A 1YW8A 1N51A 4RGZ1 2G6PA 3PKEA 1R5HA 2GG8A 2EA4A 3PKCA 1B59A 3BIQA 2NQ6A 3S6BA 5CDEA 4Z7MA 4RZZA 4B28A 1R58A 1BN5A 2EVMA 5CDLA 1WLRA 1QXZA 1M35A 4U6WA 3PKBA 2EA2A 3MX6A 4IECA 2BN7A 1XGOA 4PNCA 1YJ3A 4ZWOA 4U6CA 4U6ZA 1W2MA 2BHAA 1WL9A 2GGCA 1CHMA 1C22A 1R5GA 4FUKA 4IU6A 4IPAA 4R60A 5D6FA 2GU6A 2Q92A 4A6VA 5JI6A 1QZYA 4U6JA 4U75A 2GU4A 2GU7A 2P9AA 4U1BA 5FCFA 2BHCA 2IW2A 3IU9A 2B3LA 2BHBA 2V3XA 4IKUA 5FCHA 5CLSA 5CDVA 2Q8KA 4U76A 2EVCA 3BIPA
chains in the Genus database with same CATH topology
2Q96A 2GA2A 5E5BA 2V3ZA 3RORA 2GG5A 2BWSA 2MATA 4FLKA 4U73A 4S2TP 2OKNA 2V3YA 2GGBA 4ZNGA 3MATA 3TAVA 1BOAA 4FLJA 4ZWUA 2V6CA 1KQ0A 2DFIA 2Q94A 4U69A 2GG9A 4U70A 4FLIA 3FMRA 3BITA 2OAZA 4FKCA 1Y1NA 2NQ7A 1JAWA 4KM3A 4PV4A 4EGEA 5CNXA 4ZWPA 1C24A 2GU5A 1O0XA 1W7VA 4IKTA 4HXXA 2B3HA 5D6EA 1XGNA 4IF7A 1C23A 3IU7A 3TB5A 2Q93A 3D27A 2BWWA 3PKDA 1KP0A 4QR8A 3RVAA 1QXYA 1WY2A 3MR1A 3CB5A 2BWXA 4FO7A 2GZ5A 2BWVA 2HOWA 2BHDA 3CTZA 3IG4A 2ADUA 1XGSA 2ZSGA 1A16A 2EVOA 1WN1A 1QXWA 1B6AA 2Q95A 3Q6DA 4IDYA 1WBQA 4JUQA 5CE6A 1KQ9A 5CIKA 1YW7A 3FM3A 2BB7A 3IU8A 1YW9A 4S01A 3L7GA 1PV9A 1XNZA 1C21A 1MATA 1WL6A 4U71A 4FO8A 5JHUA 2BWYA 4IKRA 2BWTA 4S00A 2GG3A 2P98A 4MATA 1C27A 2P99A 1XGMA 4A6WA 2GG2A 4RZYA 1YVMA 4U6EA 2GTXA 3FMQA 2GG7A 4IKSA 2GG0A 2BWUA 2B3KA 4FLLA 2BH3A 3CB6A 4OOKA 4S2RP 3PKAA 1WKMA 5JFRA 3L24A 1YW8A 1N51A 4RGZ1 2G6PA 3PKEA 1R5HA 2GG8A 2EA4A 3PKCA 1B59A 3BIQA 2NQ6A 3S6BA 5CDEA 4Z7MA 4RZZA 4B28A 1R58A 1BN5A 2EVMA 5CDLA 1WLRA 1QXZA 1M35A 4U6WA 3PKBA 2EA2A 3MX6A 4IECA 2BN7A 1XGOA 4PNCA 1YJ3A 4ZWOA 4U6CA 4U6ZA 1W2MA 2BHAA 1WL9A 2GGCA 1CHMA 1C22A 1R5GA 4FUKA 4IU6A 4IPAA 4R60A 5D6FA 2GU6A 2Q92A 4A6VA 5JI6A 1QZYA 4U6JA 4U75A 2GU4A 2GU7A 2P9AA 4U1BA 5FCFA 2BHCA 2IW2A 3IU9A 2B3LA 2BHBA 2V3XA 4IKUA 5FCHA 5CLSA 5CDVA 2Q8KA 4U76A 2EVCA 3BIPA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2Q96 A;  2GA2 A;  5E5B A;  2V3Z A;  3ROR A;  2GG5 A;  2BWS A;  2MAT A;  4FLK A;  4U73 A;  4S2T P;  2OKN A;  2V3Y A;  2GGB A;  4ZNG A;  3MAT A;  3TAV A;  1BOA A;  4FLJ A;  4ZWU A;  2V6C A;  1KQ0 A;  2DFI A;  2Q94 A;  4U69 A;  2GG9 A;  4U70 A;  4FLI A;  3FMR A;  3BIT A;  2OAZ A;  4FKC A;  1Y1N A;  2NQ7 A;  1JAW A;  4KM3 A;  4PV4 A;  4EGE A;  5CNX A;  4ZWP A;  1C24 A;  2GU5 A;  1O0X A;  1W7V A;  4IKT A;  4HXX A;  2B3H A;  5D6E A;  1XGN A;  4IF7 A;  1C23 A;  3IU7 A;  3TB5 A;  2Q93 A;  3D27 A;  2BWW A;  3PKD A;  1KP0 A;  4QR8 A;  3RVA A;  1QXY A;  1WY2 A;  3MR1 A;  3CB5 A;  2BWX A;  4FO7 A;  2GZ5 A;  2BWV A;  2HOW A;  2BHD A;  3CTZ A;  3IG4 A;  2ADU A;  1XGS A;  2ZSG A;  1A16 A;  2EVO A;  1WN1 A;  1QXW A;  1B6A A;  2Q95 A;  3Q6D A;  4IDY A;  1WBQ A;  4JUQ A;  5CE6 A;  1KQ9 A;  5CIK A;  1YW7 A;  3FM3 A;  2BB7 A;  3IU8 A;  1YW9 A;  4S01 A;  3L7G A;  1PV9 A;  1XNZ A;  1C21 A;  1MAT A;  1WL6 A;  4U71 A;  4FO8 A;  5JHU A;  2BWY A;  4IKR A;  2BWT A;  4S00 A;  2GG3 A;  2P98 A;  4MAT A;  1C27 A;  2P99 A;  1XGM A;  4A6W A;  2GG2 A;  4RZY A;  1YVM A;  4U6E A;  2GTX A;  3FMQ A;  2GG7 A;  4IKS A;  2GG0 A;  2BWU A;  2B3K A;  4FLL A;  2BH3 A;  3CB6 A;  4OOK A;  4S2R P;  3PKA A;  1WKM A;  5JFR A;  3L24 A;  1YW8 A;  1N51 A;  4RGZ 1;  2G6P A;  3PKE A;  1R5H A;  2GG8 A;  2EA4 A;  3PKC A;  1B59 A;  3BIQ A;  2NQ6 A;  3S6B A;  5CDE A;  4Z7M A;  4RZZ A;  4B28 A;  1R58 A;  1BN5 A;  2EVM A;  5CDL A;  1WLR A;  1QXZ A;  1M35 A;  4U6W A;  3PKB A;  2EA2 A;  3MX6 A;  4IEC A;  2BN7 A;  1XGO A;  4PNC A;  1YJ3 A;  4ZWO A;  4U6C A;  4U6Z A;  1W2M A;  2BHA A;  1WL9 A;  2GGC A;  1CHM A;  1C22 A;  1R5G A;  4FUK A;  4IU6 A;  4IPA A;  4R60 A;  5D6F A;  2GU6 A;  2Q92 A;  4A6V A;  5JI6 A;  1QZY A;  4U6J A;  4U75 A;  2GU4 A;  2GU7 A;  2P9A A;  4U1B A;  5FCF A;  2BHC A;  2IW2 A;  3IU9 A;  2B3L A;  2BHB A;  2V3X A;  4IKU A;  5FCH A;  5CLS A;  5CDV A;  2Q8K A;  4U76 A;  2EVC A;  3BIP A; 
#chains in the Genus database with same CATH topology
 2Q96 A;  2GA2 A;  5E5B A;  2V3Z A;  3ROR A;  2GG5 A;  2BWS A;  2MAT A;  4FLK A;  4U73 A;  4S2T P;  2OKN A;  2V3Y A;  2GGB A;  4ZNG A;  3MAT A;  3TAV A;  1BOA A;  4FLJ A;  4ZWU A;  2V6C A;  1KQ0 A;  2DFI A;  2Q94 A;  4U69 A;  2GG9 A;  4U70 A;  4FLI A;  3FMR A;  3BIT A;  2OAZ A;  4FKC A;  1Y1N A;  2NQ7 A;  1JAW A;  4KM3 A;  4PV4 A;  4EGE A;  5CNX A;  4ZWP A;  1C24 A;  2GU5 A;  1O0X A;  1W7V A;  4IKT A;  4HXX A;  2B3H A;  5D6E A;  1XGN A;  4IF7 A;  1C23 A;  3IU7 A;  3TB5 A;  2Q93 A;  3D27 A;  2BWW A;  3PKD A;  1KP0 A;  4QR8 A;  3RVA A;  1QXY A;  1WY2 A;  3MR1 A;  3CB5 A;  2BWX A;  4FO7 A;  2GZ5 A;  2BWV A;  2HOW A;  2BHD A;  3CTZ A;  3IG4 A;  2ADU A;  1XGS A;  2ZSG A;  1A16 A;  2EVO A;  1WN1 A;  1QXW A;  1B6A A;  2Q95 A;  3Q6D A;  4IDY A;  1WBQ A;  4JUQ A;  5CE6 A;  1KQ9 A;  5CIK A;  1YW7 A;  3FM3 A;  2BB7 A;  3IU8 A;  1YW9 A;  4S01 A;  3L7G A;  1PV9 A;  1XNZ A;  1C21 A;  1MAT A;  1WL6 A;  4U71 A;  4FO8 A;  5JHU A;  2BWY A;  4IKR A;  2BWT A;  4S00 A;  2GG3 A;  2P98 A;  4MAT A;  1C27 A;  2P99 A;  1XGM A;  4A6W A;  2GG2 A;  4RZY A;  1YVM A;  4U6E A;  2GTX A;  3FMQ A;  2GG7 A;  4IKS A;  2GG0 A;  2BWU A;  2B3K A;  4FLL A;  2BH3 A;  3CB6 A;  4OOK A;  4S2R P;  3PKA A;  1WKM A;  5JFR A;  3L24 A;  1YW8 A;  1N51 A;  4RGZ 1;  2G6P A;  3PKE A;  1R5H A;  2GG8 A;  2EA4 A;  3PKC A;  1B59 A;  3BIQ A;  2NQ6 A;  3S6B A;  5CDE A;  4Z7M A;  4RZZ A;  4B28 A;  1R58 A;  1BN5 A;  2EVM A;  5CDL A;  1WLR A;  1QXZ A;  1M35 A;  4U6W A;  3PKB A;  2EA2 A;  3MX6 A;  4IEC A;  2BN7 A;  1XGO A;  4PNC A;  1YJ3 A;  4ZWO A;  4U6C A;  4U6Z A;  1W2M A;  2BHA A;  1WL9 A;  2GGC A;  1CHM A;  1C22 A;  1R5G A;  4FUK A;  4IU6 A;  4IPA A;  4R60 A;  5D6F A;  2GU6 A;  2Q92 A;  4A6V A;  5JI6 A;  1QZY A;  4U6J A;  4U75 A;  2GU4 A;  2GU7 A;  2P9A A;  4U1B A;  5FCF A;  2BHC A;  2IW2 A;  3IU9 A;  2B3L A;  2BHB A;  2V3X A;  4IKU A;  5FCH A;  5CLS A;  5CDV A;  2Q8K A;  4U76 A;  2EVC A;  3BIP A; 
#chains in the Genus database with same CATH homology
 2Q96 A;  2GA2 A;  5E5B A;  2V3Z A;  3ROR A;  2GG5 A;  2BWS A;  2MAT A;  4FLK A;  4U73 A;  4S2T P;  2OKN A;  2V3Y A;  2GGB A;  4ZNG A;  3MAT A;  3TAV A;  1BOA A;  4FLJ A;  4ZWU A;  2V6C A;  1KQ0 A;  2DFI A;  2Q94 A;  4U69 A;  2GG9 A;  4U70 A;  4FLI A;  3FMR A;  3BIT A;  2OAZ A;  4FKC A;  1Y1N A;  2NQ7 A;  1JAW A;  4KM3 A;  4PV4 A;  4EGE A;  5CNX A;  4ZWP A;  1C24 A;  2GU5 A;  1O0X A;  1W7V A;  4IKT A;  4HXX A;  2B3H A;  5D6E A;  1XGN A;  4IF7 A;  1C23 A;  3IU7 A;  3TB5 A;  2Q93 A;  3D27 A;  2BWW A;  3PKD A;  1KP0 A;  4QR8 A;  3RVA A;  1QXY A;  1WY2 A;  3MR1 A;  3CB5 A;  2BWX A;  4FO7 A;  2GZ5 A;  2BWV A;  2HOW A;  2BHD A;  3CTZ A;  3IG4 A;  2ADU A;  1XGS A;  2ZSG A;  1A16 A;  2EVO A;  1WN1 A;  1QXW A;  1B6A A;  2Q95 A;  3Q6D A;  4IDY A;  1WBQ A;  4JUQ A;  5CE6 A;  1KQ9 A;  5CIK A;  1YW7 A;  3FM3 A;  2BB7 A;  3IU8 A;  1YW9 A;  4S01 A;  3L7G A;  1PV9 A;  1XNZ A;  1C21 A;  1MAT A;  1WL6 A;  4U71 A;  4FO8 A;  5JHU A;  2BWY A;  4IKR A;  2BWT A;  4S00 A;  2GG3 A;  2P98 A;  4MAT A;  1C27 A;  2P99 A;  1XGM A;  4A6W A;  2GG2 A;  4RZY A;  1YVM A;  4U6E A;  2GTX A;  3FMQ A;  2GG7 A;  4IKS A;  2GG0 A;  2BWU A;  2B3K A;  4FLL A;  2BH3 A;  3CB6 A;  4OOK A;  4S2R P;  3PKA A;  1WKM A;  5JFR A;  3L24 A;  1YW8 A;  1N51 A;  4RGZ 1;  2G6P A;  3PKE A;  1R5H A;  2GG8 A;  2EA4 A;  3PKC A;  1B59 A;  3BIQ A;  2NQ6 A;  3S6B A;  5CDE A;  4Z7M A;  4RZZ A;  4B28 A;  1R58 A;  1BN5 A;  2EVM A;  5CDL A;  1WLR A;  1QXZ A;  1M35 A;  4U6W A;  3PKB A;  2EA2 A;  3MX6 A;  4IEC A;  2BN7 A;  1XGO A;  4PNC A;  1YJ3 A;  4ZWO A;  4U6C A;  4U6Z A;  1W2M A;  2BHA A;  1WL9 A;  2GGC A;  1CHM A;  1C22 A;  1R5G A;  4FUK A;  4IU6 A;  4IPA A;  4R60 A;  5D6F A;  2GU6 A;  2Q92 A;  4A6V A;  5JI6 A;  1QZY A;  4U6J A;  4U75 A;  2GU4 A;  2GU7 A;  2P9A A;  4U1B A;  5FCF A;  2BHC A;  2IW2 A;  3IU9 A;  2B3L A;  2BHB A;  2V3X A;  4IKU A;  5FCH A;  5CLS A;  5CDV A;  2Q8K A;  4U76 A;  2EVC A;  3BIP A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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