3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
1A16A 1QXZA 2BN7A 3PKBA 1WBQA 2P99A 3IU7A 4U69A 1WN1A 4U70A 4S2RP 5E5BA 2BB7A 1YVMA 1Y1NA 4FKCA 1XGMA 4S01A 4IPAA 3CB6A 1QXWA 2GU6A 2Q95A 3RORA 4FLLA 4FLIA 5CDVA 3PKDA 2GTXA 4FLJA 1PV9A 3PKCA 2BWXA 4U6ZA 1KP0A 2V3XA 5CDEA 4IKRA 2BWSA 3BITA 1QXYA 4HXXA 4S2TP 1WL9A 1XGNA 2EVMA 2V3YA 1C22A 4FLKA 1W7VA 2GA2A 1R58A 2Q93A 3CTZA 1WY2A 2GGBA 2BHCA 1XNZA 2MATA 3S6BA 1QZYA 2B3KA 4IKSA 5CE6A 1WL6A 2EA2A 1B6AA 4FUKA 1WKMA 1C21A 4FO7A 4IKUA 1BOAA 4PV4A 3RVAA 1W2MA 4U6CA 1C24A 1C23A 2HOWA 5JI6A 3TB5A 1R5GA 1YW7A 3FMQA 4QR8A 3IG4A 2BHDA 2GU4A 4JUQA 5D6FA 2ZSGA 4IKTA 2GG8A 4U6WA 3PKAA 2BHBA 2V6CA 2BWUA 4U75A 4RZYA 4S00A 2P98A 1N51A 2Q92A 5FCFA 2GG5A 1O0XA 4U1BA 5D6EA 2BWTA 4ZWOA 2B3HA 4U71A 2V3ZA 4MATA 4FO8A 4U76A 3FM3A 2OKNA 3PKEA 2G6PA 2GGCA 2GG7A 1R5HA 2BHAA 1JAWA 3BIQA 4KM3A 4B28A 5FCHA 1MATA 1C27A 2GG2A 2B3LA 2Q96A 2EA4A 1XGSA 1WLRA 2GG0A 2GU5A 2GZ5A 5JHUA 2GG9A 4U6JA 1YW8A 5CLSA 3D27A 2EVCA 4ZWPA 4ZWUA 1KQ9A 5CDLA 3L7GA 1M35A 1XGOA 5CNXA 4IF7A 4RGZ1 5CIKA 3Q6DA 3BIPA 3IU9A 2Q8KA 1YJ3A 2DFIA 3TAVA 4A6VA 4A6WA 4R60A 2BH3A 3MR1A 4PNCA 3MATA 2ADUA 2NQ6A 3CB5A 1BN5A 1B59A 4Z7MA 2BWWA 3MX6A 4RZZA 5JFRA 2P9AA 1CHMA 3IU8A 4IDYA 4ZNGA 1YW9A 4EGEA 2NQ7A 2OAZA 2IW2A 2Q94A 3FMRA 4U6EA 4U73A 4OOKA 2BWYA 2EVOA 4IECA 2BWVA 3L24A 1KQ0A 2GG3A 4IU6A 2GU7A
chains in the Genus database with same CATH superfamily
1A16A 1QXZA 2BN7A 3PKBA 1WBQA 2P99A 3IU7A 4U69A 1WN1A 4U70A 4S2RP 5E5BA 2BB7A 1YVMA 1Y1NA 4FKCA 1XGMA 4S01A 4IPAA 3CB6A 1QXWA 2GU6A 2Q95A 3RORA 4FLLA 4FLIA 5CDVA 3PKDA 2GTXA 4FLJA 1PV9A 3PKCA 2BWXA 4U6ZA 1KP0A 2V3XA 5CDEA 4IKRA 2BWSA 3BITA 1QXYA 4HXXA 4S2TP 1WL9A 1XGNA 2EVMA 2V3YA 1C22A 4FLKA 1W7VA 2GA2A 1R58A 2Q93A 3CTZA 1WY2A 2GGBA 2BHCA 1XNZA 2MATA 3S6BA 1QZYA 2B3KA 4IKSA 5CE6A 1WL6A 2EA2A 1B6AA 4FUKA 1WKMA 1C21A 4FO7A 4IKUA 1BOAA 4PV4A 3RVAA 1W2MA 4U6CA 1C24A 1C23A 2HOWA 5JI6A 3TB5A 1R5GA 1YW7A 3FMQA 4QR8A 3IG4A 2BHDA 2GU4A 4JUQA 5D6FA 2ZSGA 4IKTA 2GG8A 4U6WA 3PKAA 2BHBA 2V6CA 2BWUA 4U75A 4RZYA 4S00A 2P98A 1N51A 2Q92A 5FCFA 2GG5A 1O0XA 4U1BA 5D6EA 2BWTA 4ZWOA 2B3HA 4U71A 2V3ZA 4MATA 4FO8A 4U76A 3FM3A 2OKNA 3PKEA 2G6PA 2GGCA 2GG7A 1R5HA 2BHAA 1JAWA 3BIQA 4KM3A 4B28A 5FCHA 1MATA 1C27A 2GG2A 2B3LA 2Q96A 2EA4A 1XGSA 1WLRA 2GG0A 2GU5A 2GZ5A 5JHUA 2GG9A 4U6JA 1YW8A 5CLSA 3D27A 2EVCA 4ZWPA 4ZWUA 1KQ9A 5CDLA 3L7GA 1M35A 1XGOA 5CNXA 4IF7A 4RGZ1 5CIKA 3Q6DA 3BIPA 3IU9A 2Q8KA 1YJ3A 2DFIA 3TAVA 4A6VA 4A6WA 4R60A 2BH3A 3MR1A 4PNCA 3MATA 2ADUA 2NQ6A 3CB5A 1BN5A 1B59A 4Z7MA 2BWWA 3MX6A 4RZZA 5JFRA 2P9AA 1CHMA 3IU8A 4IDYA 4ZNGA 1YW9A 4EGEA 2NQ7A 2OAZA 2IW2A 2Q94A 3FMRA 4U6EA 4U73A 4OOKA 2BWYA 2EVOA 4IECA 2BWVA 3L24A 1KQ0A 2GG3A 4IU6A 2GU7A
chains in the Genus database with same CATH topology
1A16A 1QXZA 2BN7A 3PKBA 1WBQA 2P99A 3IU7A 4U69A 1WN1A 4U70A 4S2RP 5E5BA 2BB7A 1YVMA 1Y1NA 4FKCA 1XGMA 4S01A 4IPAA 3CB6A 1QXWA 2GU6A 2Q95A 3RORA 4FLLA 4FLIA 5CDVA 3PKDA 2GTXA 4FLJA 1PV9A 3PKCA 2BWXA 4U6ZA 1KP0A 2V3XA 5CDEA 4IKRA 2BWSA 3BITA 1QXYA 4HXXA 4S2TP 1WL9A 1XGNA 2EVMA 2V3YA 1C22A 4FLKA 1W7VA 2GA2A 1R58A 2Q93A 3CTZA 1WY2A 2GGBA 2BHCA 1XNZA 2MATA 3S6BA 1QZYA 2B3KA 4IKSA 5CE6A 1WL6A 2EA2A 1B6AA 4FUKA 1WKMA 1C21A 4FO7A 4IKUA 1BOAA 4PV4A 3RVAA 1W2MA 4U6CA 1C24A 1C23A 2HOWA 5JI6A 3TB5A 1R5GA 1YW7A 3FMQA 4QR8A 3IG4A 2BHDA 2GU4A 4JUQA 5D6FA 2ZSGA 4IKTA 2GG8A 4U6WA 3PKAA 2BHBA 2V6CA 2BWUA 4U75A 4RZYA 4S00A 2P98A 1N51A 2Q92A 5FCFA 2GG5A 1O0XA 4U1BA 5D6EA 2BWTA 4ZWOA 2B3HA 4U71A 2V3ZA 4MATA 4FO8A 4U76A 3FM3A 2OKNA 3PKEA 2G6PA 2GGCA 2GG7A 1R5HA 2BHAA 1JAWA 3BIQA 4KM3A 4B28A 5FCHA 1MATA 1C27A 2GG2A 2B3LA 2Q96A 2EA4A 1XGSA 1WLRA 2GG0A 2GU5A 2GZ5A 5JHUA 2GG9A 4U6JA 1YW8A 5CLSA 3D27A 2EVCA 4ZWPA 4ZWUA 1KQ9A 5CDLA 3L7GA 1M35A 1XGOA 5CNXA 4IF7A 4RGZ1 5CIKA 3Q6DA 3BIPA 3IU9A 2Q8KA 1YJ3A 2DFIA 3TAVA 4A6VA 4A6WA 4R60A 2BH3A 3MR1A 4PNCA 3MATA 2ADUA 2NQ6A 3CB5A 1BN5A 1B59A 4Z7MA 2BWWA 3MX6A 4RZZA 5JFRA 2P9AA 1CHMA 3IU8A 4IDYA 4ZNGA 1YW9A 4EGEA 2NQ7A 2OAZA 2IW2A 2Q94A 3FMRA 4U6EA 4U73A 4OOKA 2BWYA 2EVOA 4IECA 2BWVA 3L24A 1KQ0A 2GG3A 4IU6A 2GU7A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1A16 A;  1QXZ A;  2BN7 A;  3PKB A;  1WBQ A;  2P99 A;  3IU7 A;  4U69 A;  1WN1 A;  4U70 A;  4S2R P;  5E5B A;  2BB7 A;  1YVM A;  1Y1N A;  4FKC A;  1XGM A;  4S01 A;  4IPA A;  3CB6 A;  1QXW A;  2GU6 A;  2Q95 A;  3ROR A;  4FLL A;  4FLI A;  5CDV A;  3PKD A;  2GTX A;  4FLJ A;  1PV9 A;  3PKC A;  2BWX A;  4U6Z A;  1KP0 A;  2V3X A;  5CDE A;  4IKR A;  2BWS A;  3BIT A;  1QXY A;  4HXX A;  4S2T P;  1WL9 A;  1XGN A;  2EVM A;  2V3Y A;  1C22 A;  4FLK A;  1W7V A;  2GA2 A;  1R58 A;  2Q93 A;  3CTZ A;  1WY2 A;  2GGB A;  2BHC A;  1XNZ A;  2MAT A;  3S6B A;  1QZY A;  2B3K A;  4IKS A;  5CE6 A;  1WL6 A;  2EA2 A;  1B6A A;  4FUK A;  1WKM A;  1C21 A;  4FO7 A;  4IKU A;  1BOA A;  4PV4 A;  3RVA A;  1W2M A;  4U6C A;  1C24 A;  1C23 A;  2HOW A;  5JI6 A;  3TB5 A;  1R5G A;  1YW7 A;  3FMQ A;  4QR8 A;  3IG4 A;  2BHD A;  2GU4 A;  4JUQ A;  5D6F A;  2ZSG A;  4IKT A;  2GG8 A;  4U6W A;  3PKA A;  2BHB A;  2V6C A;  2BWU A;  4U75 A;  4RZY A;  4S00 A;  2P98 A;  1N51 A;  2Q92 A;  5FCF A;  2GG5 A;  1O0X A;  4U1B A;  5D6E A;  2BWT A;  4ZWO A;  2B3H A;  4U71 A;  2V3Z A;  4MAT A;  4FO8 A;  4U76 A;  3FM3 A;  2OKN A;  3PKE A;  2G6P A;  2GGC A;  2GG7 A;  1R5H A;  2BHA A;  1JAW A;  3BIQ A;  4KM3 A;  4B28 A;  5FCH A;  1MAT A;  1C27 A;  2GG2 A;  2B3L A;  2Q96 A;  2EA4 A;  1XGS A;  1WLR A;  2GG0 A;  2GU5 A;  2GZ5 A;  5JHU A;  2GG9 A;  4U6J A;  1YW8 A;  5CLS A;  3D27 A;  2EVC A;  4ZWP A;  4ZWU A;  1KQ9 A;  5CDL A;  3L7G A;  1M35 A;  1XGO A;  5CNX A;  4IF7 A;  4RGZ 1;  5CIK A;  3Q6D A;  3BIP A;  3IU9 A;  2Q8K A;  1YJ3 A;  2DFI A;  3TAV A;  4A6V A;  4A6W A;  4R60 A;  2BH3 A;  3MR1 A;  4PNC A;  3MAT A;  2ADU A;  2NQ6 A;  3CB5 A;  1BN5 A;  1B59 A;  4Z7M A;  2BWW A;  3MX6 A;  4RZZ A;  5JFR A;  2P9A A;  1CHM A;  3IU8 A;  4IDY A;  4ZNG A;  1YW9 A;  4EGE A;  2NQ7 A;  2OAZ A;  2IW2 A;  2Q94 A;  3FMR A;  4U6E A;  4U73 A;  4OOK A;  2BWY A;  2EVO A;  4IEC A;  2BWV A;  3L24 A;  1KQ0 A;  2GG3 A;  4IU6 A;  2GU7 A; 
#chains in the Genus database with same CATH topology
 1A16 A;  1QXZ A;  2BN7 A;  3PKB A;  1WBQ A;  2P99 A;  3IU7 A;  4U69 A;  1WN1 A;  4U70 A;  4S2R P;  5E5B A;  2BB7 A;  1YVM A;  1Y1N A;  4FKC A;  1XGM A;  4S01 A;  4IPA A;  3CB6 A;  1QXW A;  2GU6 A;  2Q95 A;  3ROR A;  4FLL A;  4FLI A;  5CDV A;  3PKD A;  2GTX A;  4FLJ A;  1PV9 A;  3PKC A;  2BWX A;  4U6Z A;  1KP0 A;  2V3X A;  5CDE A;  4IKR A;  2BWS A;  3BIT A;  1QXY A;  4HXX A;  4S2T P;  1WL9 A;  1XGN A;  2EVM A;  2V3Y A;  1C22 A;  4FLK A;  1W7V A;  2GA2 A;  1R58 A;  2Q93 A;  3CTZ A;  1WY2 A;  2GGB A;  2BHC A;  1XNZ A;  2MAT A;  3S6B A;  1QZY A;  2B3K A;  4IKS A;  5CE6 A;  1WL6 A;  2EA2 A;  1B6A A;  4FUK A;  1WKM A;  1C21 A;  4FO7 A;  4IKU A;  1BOA A;  4PV4 A;  3RVA A;  1W2M A;  4U6C A;  1C24 A;  1C23 A;  2HOW A;  5JI6 A;  3TB5 A;  1R5G A;  1YW7 A;  3FMQ A;  4QR8 A;  3IG4 A;  2BHD A;  2GU4 A;  4JUQ A;  5D6F A;  2ZSG A;  4IKT A;  2GG8 A;  4U6W A;  3PKA A;  2BHB A;  2V6C A;  2BWU A;  4U75 A;  4RZY A;  4S00 A;  2P98 A;  1N51 A;  2Q92 A;  5FCF A;  2GG5 A;  1O0X A;  4U1B A;  5D6E A;  2BWT A;  4ZWO A;  2B3H A;  4U71 A;  2V3Z A;  4MAT A;  4FO8 A;  4U76 A;  3FM3 A;  2OKN A;  3PKE A;  2G6P A;  2GGC A;  2GG7 A;  1R5H A;  2BHA A;  1JAW A;  3BIQ A;  4KM3 A;  4B28 A;  5FCH A;  1MAT A;  1C27 A;  2GG2 A;  2B3L A;  2Q96 A;  2EA4 A;  1XGS A;  1WLR A;  2GG0 A;  2GU5 A;  2GZ5 A;  5JHU A;  2GG9 A;  4U6J A;  1YW8 A;  5CLS A;  3D27 A;  2EVC A;  4ZWP A;  4ZWU A;  1KQ9 A;  5CDL A;  3L7G A;  1M35 A;  1XGO A;  5CNX A;  4IF7 A;  4RGZ 1;  5CIK A;  3Q6D A;  3BIP A;  3IU9 A;  2Q8K A;  1YJ3 A;  2DFI A;  3TAV A;  4A6V A;  4A6W A;  4R60 A;  2BH3 A;  3MR1 A;  4PNC A;  3MAT A;  2ADU A;  2NQ6 A;  3CB5 A;  1BN5 A;  1B59 A;  4Z7M A;  2BWW A;  3MX6 A;  4RZZ A;  5JFR A;  2P9A A;  1CHM A;  3IU8 A;  4IDY A;  4ZNG A;  1YW9 A;  4EGE A;  2NQ7 A;  2OAZ A;  2IW2 A;  2Q94 A;  3FMR A;  4U6E A;  4U73 A;  4OOK A;  2BWY A;  2EVO A;  4IEC A;  2BWV A;  3L24 A;  1KQ0 A;  2GG3 A;  4IU6 A;  2GU7 A; 
#chains in the Genus database with same CATH homology
 1A16 A;  1QXZ A;  2BN7 A;  3PKB A;  1WBQ A;  2P99 A;  3IU7 A;  4U69 A;  1WN1 A;  4U70 A;  4S2R P;  5E5B A;  2BB7 A;  1YVM A;  1Y1N A;  4FKC A;  1XGM A;  4S01 A;  4IPA A;  3CB6 A;  1QXW A;  2GU6 A;  2Q95 A;  3ROR A;  4FLL A;  4FLI A;  5CDV A;  3PKD A;  2GTX A;  4FLJ A;  1PV9 A;  3PKC A;  2BWX A;  4U6Z A;  1KP0 A;  2V3X A;  5CDE A;  4IKR A;  2BWS A;  3BIT A;  1QXY A;  4HXX A;  4S2T P;  1WL9 A;  1XGN A;  2EVM A;  2V3Y A;  1C22 A;  4FLK A;  1W7V A;  2GA2 A;  1R58 A;  2Q93 A;  3CTZ A;  1WY2 A;  2GGB A;  2BHC A;  1XNZ A;  2MAT A;  3S6B A;  1QZY A;  2B3K A;  4IKS A;  5CE6 A;  1WL6 A;  2EA2 A;  1B6A A;  4FUK A;  1WKM A;  1C21 A;  4FO7 A;  4IKU A;  1BOA A;  4PV4 A;  3RVA A;  1W2M A;  4U6C A;  1C24 A;  1C23 A;  2HOW A;  5JI6 A;  3TB5 A;  1R5G A;  1YW7 A;  3FMQ A;  4QR8 A;  3IG4 A;  2BHD A;  2GU4 A;  4JUQ A;  5D6F A;  2ZSG A;  4IKT A;  2GG8 A;  4U6W A;  3PKA A;  2BHB A;  2V6C A;  2BWU A;  4U75 A;  4RZY A;  4S00 A;  2P98 A;  1N51 A;  2Q92 A;  5FCF A;  2GG5 A;  1O0X A;  4U1B A;  5D6E A;  2BWT A;  4ZWO A;  2B3H A;  4U71 A;  2V3Z A;  4MAT A;  4FO8 A;  4U76 A;  3FM3 A;  2OKN A;  3PKE A;  2G6P A;  2GGC A;  2GG7 A;  1R5H A;  2BHA A;  1JAW A;  3BIQ A;  4KM3 A;  4B28 A;  5FCH A;  1MAT A;  1C27 A;  2GG2 A;  2B3L A;  2Q96 A;  2EA4 A;  1XGS A;  1WLR A;  2GG0 A;  2GU5 A;  2GZ5 A;  5JHU A;  2GG9 A;  4U6J A;  1YW8 A;  5CLS A;  3D27 A;  2EVC A;  4ZWP A;  4ZWU A;  1KQ9 A;  5CDL A;  3L7G A;  1M35 A;  1XGO A;  5CNX A;  4IF7 A;  4RGZ 1;  5CIK A;  3Q6D A;  3BIP A;  3IU9 A;  2Q8K A;  1YJ3 A;  2DFI A;  3TAV A;  4A6V A;  4A6W A;  4R60 A;  2BH3 A;  3MR1 A;  4PNC A;  3MAT A;  2ADU A;  2NQ6 A;  3CB5 A;  1BN5 A;  1B59 A;  4Z7M A;  2BWW A;  3MX6 A;  4RZZ A;  5JFR A;  2P9A A;  1CHM A;  3IU8 A;  4IDY A;  4ZNG A;  1YW9 A;  4EGE A;  2NQ7 A;  2OAZ A;  2IW2 A;  2Q94 A;  3FMR A;  4U6E A;  4U73 A;  4OOK A;  2BWY A;  2EVO A;  4IEC A;  2BWV A;  3L24 A;  1KQ0 A;  2GG3 A;  4IU6 A;  2GU7 A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite