3MATA

E.coli methionine aminopeptidase transition-state inhibitor complex
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
264
structure length
264
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Escherichia coli
publication title Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
pubmed doi rcsb
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 86
structure length 264
sequence length 264
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3matA00
1WKMA 2EVOA 5D6EA 1C22A 5D6FA 4Z7MA 1CHMA 4FLLA 4QR8A 1QXYA 1R5GA 4U73A 3PKAA 4JUQA 4S01A 1WBQA 3FMQA 1QZYA 4FLIA 4A6VA 4S2TP 4U6CA 2V3YA 3BIPA 1R5HA 2GTXA 2P9AA 1QXWA 4S00A 1KP0A 4PNCA 2GU7A 4KM3A 1XGOA 4IPAA 5CDLA 2Q96A 3RORA 3TAVA 2Q95A 4U69A 2BHBA 1R58A 4U76A 5CE6A 4U6JA 2Q92A 2DFIA 2GG8A 3IU7A 2EVCA 1XGNA 2EVMA 3TB5A 2B3KA 2GGBA 3IG4A 1BOAA 2GZ5A 4B28A 5FCFA 2GA2A 1WN1A 2GU4A 5JHUA 4R60A 2BB7A 4U6WA 2BWWA 4U71A 5JFRA 1JAWA 3Q6DA 2OAZA 1B6AA 1XGMA 2BWTA 2IW2A 5JI6A 1QXZA 4ZWOA 4IKRA 2BWYA 1A16A 1M35A 1N51A 2BWSA 4U1BA 2BWXA 4A6WA 1YJ3A 3BIQA 2NQ6A 1WLRA 4OOKA 2GG0A 2MATA 2OKNA 5CNXA 1WL9A 4FLJA 2BWVA 1PV9A 2BH3A 4FLKA 1W7VA 2BN7A 3PKCA 3S6BA 2Q94A 2GG7A 5CDVA 3IU8A 3PKBA 3RVAA 4U6ZA 1W2MA 1XGSA 4ZNGA 2GG5A 2ZSGA 3FM3A 2GG3A 3IU9A 2GG9A 3L7GA 1YW9A 4IKUA 3CB5A 4FKCA 4IKTA 3CTZA 4IKSA 5CIKA 2BWUA 1B59A 4U70A 4HXXA 1WL6A 1O0XA 2GGCA 4IECA 4FO8A 5CDEA 2BHDA 2HOWA 2Q93A 4RGZ1 2BHAA 3MATA 1WY2A 1BN5A 3MX6A 3PKEA 5FCHA 1C24A 3L24A 1Y1NA 1KQ0A 2G6PA 2P98A 4FUKA 2V6CA 1XNZA 4PV4A 1MATA 2Q8KA 2B3LA 3D27A 1C27A 1YVMA 4FO7A 4IF7A 2V3ZA 4EGEA 4MATA 4IDYA 5CLSA 1KQ9A 2ADUA 1YW7A 3MR1A 3FMRA 1C23A 2EA2A 2EA4A 2P99A 1C21A 1YW8A 4U6EA 4RZZA 3CB6A 2BHCA 4IU6A 2B3HA 3PKDA 2GU6A 2GG2A 4ZWPA 2GU5A 4S2RP 5E5BA 2V3XA 3BITA 2NQ7A 4ZWUA 4RZYA 4U75A
chains in the Genus database with same CATH superfamily
1WKMA 2EVOA 5D6EA 1C22A 5D6FA 4Z7MA 1CHMA 4FLLA 4QR8A 1QXYA 1R5GA 4U73A 3PKAA 4JUQA 4S01A 1WBQA 3FMQA 1QZYA 4FLIA 4A6VA 4S2TP 4U6CA 2V3YA 3BIPA 1R5HA 2GTXA 2P9AA 1QXWA 4S00A 1KP0A 4PNCA 2GU7A 4KM3A 1XGOA 4IPAA 5CDLA 2Q96A 3RORA 3TAVA 2Q95A 4U69A 2BHBA 1R58A 4U76A 5CE6A 4U6JA 2Q92A 2DFIA 2GG8A 3IU7A 2EVCA 1XGNA 2EVMA 3TB5A 2B3KA 2GGBA 3IG4A 1BOAA 2GZ5A 4B28A 5FCFA 2GA2A 1WN1A 2GU4A 5JHUA 4R60A 2BB7A 4U6WA 2BWWA 4U71A 5JFRA 1JAWA 3Q6DA 2OAZA 1B6AA 1XGMA 2BWTA 2IW2A 5JI6A 1QXZA 4ZWOA 4IKRA 2BWYA 1A16A 1M35A 1N51A 2BWSA 4U1BA 2BWXA 4A6WA 1YJ3A 3BIQA 2NQ6A 1WLRA 4OOKA 2GG0A 2MATA 2OKNA 5CNXA 1WL9A 4FLJA 2BWVA 1PV9A 2BH3A 4FLKA 1W7VA 2BN7A 3PKCA 3S6BA 2Q94A 2GG7A 5CDVA 3IU8A 3PKBA 3RVAA 4U6ZA 1W2MA 1XGSA 4ZNGA 2GG5A 2ZSGA 3FM3A 2GG3A 3IU9A 2GG9A 3L7GA 1YW9A 4IKUA 3CB5A 4FKCA 4IKTA 3CTZA 4IKSA 5CIKA 2BWUA 1B59A 4U70A 4HXXA 1WL6A 1O0XA 2GGCA 4IECA 4FO8A 5CDEA 2BHDA 2HOWA 2Q93A 4RGZ1 2BHAA 3MATA 1WY2A 1BN5A 3MX6A 3PKEA 5FCHA 1C24A 3L24A 1Y1NA 1KQ0A 2G6PA 2P98A 4FUKA 2V6CA 1XNZA 4PV4A 1MATA 2Q8KA 2B3LA 3D27A 1C27A 1YVMA 4FO7A 4IF7A 2V3ZA 4EGEA 4MATA 4IDYA 5CLSA 1KQ9A 2ADUA 1YW7A 3MR1A 3FMRA 1C23A 2EA2A 2EA4A 2P99A 1C21A 1YW8A 4U6EA 4RZZA 3CB6A 2BHCA 4IU6A 2B3HA 3PKDA 2GU6A 2GG2A 4ZWPA 2GU5A 4S2RP 5E5BA 2V3XA 3BITA 2NQ7A 4ZWUA 4RZYA 4U75A
chains in the Genus database with same CATH topology
1WKMA 2EVOA 5D6EA 1C22A 5D6FA 4Z7MA 1CHMA 4FLLA 4QR8A 1QXYA 1R5GA 4U73A 3PKAA 4JUQA 4S01A 1WBQA 3FMQA 1QZYA 4FLIA 4A6VA 4S2TP 4U6CA 2V3YA 3BIPA 1R5HA 2GTXA 2P9AA 1QXWA 4S00A 1KP0A 4PNCA 2GU7A 4KM3A 1XGOA 4IPAA 5CDLA 2Q96A 3RORA 3TAVA 2Q95A 4U69A 2BHBA 1R58A 4U76A 5CE6A 4U6JA 2Q92A 2DFIA 2GG8A 3IU7A 2EVCA 1XGNA 2EVMA 3TB5A 2B3KA 2GGBA 3IG4A 1BOAA 2GZ5A 4B28A 5FCFA 2GA2A 1WN1A 2GU4A 5JHUA 4R60A 2BB7A 4U6WA 2BWWA 4U71A 5JFRA 1JAWA 3Q6DA 2OAZA 1B6AA 1XGMA 2BWTA 2IW2A 5JI6A 1QXZA 4ZWOA 4IKRA 2BWYA 1A16A 1M35A 1N51A 2BWSA 4U1BA 2BWXA 4A6WA 1YJ3A 3BIQA 2NQ6A 1WLRA 4OOKA 2GG0A 2MATA 2OKNA 5CNXA 1WL9A 4FLJA 2BWVA 1PV9A 2BH3A 4FLKA 1W7VA 2BN7A 3PKCA 3S6BA 2Q94A 2GG7A 5CDVA 3IU8A 3PKBA 3RVAA 4U6ZA 1W2MA 1XGSA 4ZNGA 2GG5A 2ZSGA 3FM3A 2GG3A 3IU9A 2GG9A 3L7GA 1YW9A 4IKUA 3CB5A 4FKCA 4IKTA 3CTZA 4IKSA 5CIKA 2BWUA 1B59A 4U70A 4HXXA 1WL6A 1O0XA 2GGCA 4IECA 4FO8A 5CDEA 2BHDA 2HOWA 2Q93A 4RGZ1 2BHAA 3MATA 1WY2A 1BN5A 3MX6A 3PKEA 5FCHA 1C24A 3L24A 1Y1NA 1KQ0A 2G6PA 2P98A 4FUKA 2V6CA 1XNZA 4PV4A 1MATA 2Q8KA 2B3LA 3D27A 1C27A 1YVMA 4FO7A 4IF7A 2V3ZA 4EGEA 4MATA 4IDYA 5CLSA 1KQ9A 2ADUA 1YW7A 3MR1A 3FMRA 1C23A 2EA2A 2EA4A 2P99A 1C21A 1YW8A 4U6EA 4RZZA 3CB6A 2BHCA 4IU6A 2B3HA 3PKDA 2GU6A 2GG2A 4ZWPA 2GU5A 4S2RP 5E5BA 2V3XA 3BITA 2NQ7A 4ZWUA 4RZYA 4U75A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WKM A;  2EVO A;  5D6E A;  1C22 A;  5D6F A;  4Z7M A;  1CHM A;  4FLL A;  4QR8 A;  1QXY A;  1R5G A;  4U73 A;  3PKA A;  4JUQ A;  4S01 A;  1WBQ A;  3FMQ A;  1QZY A;  4FLI A;  4A6V A;  4S2T P;  4U6C A;  2V3Y A;  3BIP A;  1R5H A;  2GTX A;  2P9A A;  1QXW A;  4S00 A;  1KP0 A;  4PNC A;  2GU7 A;  4KM3 A;  1XGO A;  4IPA A;  5CDL A;  2Q96 A;  3ROR A;  3TAV A;  2Q95 A;  4U69 A;  2BHB A;  1R58 A;  4U76 A;  5CE6 A;  4U6J A;  2Q92 A;  2DFI A;  2GG8 A;  3IU7 A;  2EVC A;  1XGN A;  2EVM A;  3TB5 A;  2B3K A;  2GGB A;  3IG4 A;  1BOA A;  2GZ5 A;  4B28 A;  5FCF A;  2GA2 A;  1WN1 A;  2GU4 A;  5JHU A;  4R60 A;  2BB7 A;  4U6W A;  2BWW A;  4U71 A;  5JFR A;  1JAW A;  3Q6D A;  2OAZ A;  1B6A A;  1XGM A;  2BWT A;  2IW2 A;  5JI6 A;  1QXZ A;  4ZWO A;  4IKR A;  2BWY A;  1A16 A;  1M35 A;  1N51 A;  2BWS A;  4U1B A;  2BWX A;  4A6W A;  1YJ3 A;  3BIQ A;  2NQ6 A;  1WLR A;  4OOK A;  2GG0 A;  2MAT A;  2OKN A;  5CNX A;  1WL9 A;  4FLJ A;  2BWV A;  1PV9 A;  2BH3 A;  4FLK A;  1W7V A;  2BN7 A;  3PKC A;  3S6B A;  2Q94 A;  2GG7 A;  5CDV A;  3IU8 A;  3PKB A;  3RVA A;  4U6Z A;  1W2M A;  1XGS A;  4ZNG A;  2GG5 A;  2ZSG A;  3FM3 A;  2GG3 A;  3IU9 A;  2GG9 A;  3L7G A;  1YW9 A;  4IKU A;  3CB5 A;  4FKC A;  4IKT A;  3CTZ A;  4IKS A;  5CIK A;  2BWU A;  1B59 A;  4U70 A;  4HXX A;  1WL6 A;  1O0X A;  2GGC A;  4IEC A;  4FO8 A;  5CDE A;  2BHD A;  2HOW A;  2Q93 A;  4RGZ 1;  2BHA A;  3MAT A;  1WY2 A;  1BN5 A;  3MX6 A;  3PKE A;  5FCH A;  1C24 A;  3L24 A;  1Y1N A;  1KQ0 A;  2G6P A;  2P98 A;  4FUK A;  2V6C A;  1XNZ A;  4PV4 A;  1MAT A;  2Q8K A;  2B3L A;  3D27 A;  1C27 A;  1YVM A;  4FO7 A;  4IF7 A;  2V3Z A;  4EGE A;  4MAT A;  4IDY A;  5CLS A;  1KQ9 A;  2ADU A;  1YW7 A;  3MR1 A;  3FMR A;  1C23 A;  2EA2 A;  2EA4 A;  2P99 A;  1C21 A;  1YW8 A;  4U6E A;  4RZZ A;  3CB6 A;  2BHC A;  4IU6 A;  2B3H A;  3PKD A;  2GU6 A;  2GG2 A;  4ZWP A;  2GU5 A;  4S2R P;  5E5B A;  2V3X A;  3BIT A;  2NQ7 A;  4ZWU A;  4RZY A;  4U75 A; 
#chains in the Genus database with same CATH topology
 1WKM A;  2EVO A;  5D6E A;  1C22 A;  5D6F A;  4Z7M A;  1CHM A;  4FLL A;  4QR8 A;  1QXY A;  1R5G A;  4U73 A;  3PKA A;  4JUQ A;  4S01 A;  1WBQ A;  3FMQ A;  1QZY A;  4FLI A;  4A6V A;  4S2T P;  4U6C A;  2V3Y A;  3BIP A;  1R5H A;  2GTX A;  2P9A A;  1QXW A;  4S00 A;  1KP0 A;  4PNC A;  2GU7 A;  4KM3 A;  1XGO A;  4IPA A;  5CDL A;  2Q96 A;  3ROR A;  3TAV A;  2Q95 A;  4U69 A;  2BHB A;  1R58 A;  4U76 A;  5CE6 A;  4U6J A;  2Q92 A;  2DFI A;  2GG8 A;  3IU7 A;  2EVC A;  1XGN A;  2EVM A;  3TB5 A;  2B3K A;  2GGB A;  3IG4 A;  1BOA A;  2GZ5 A;  4B28 A;  5FCF A;  2GA2 A;  1WN1 A;  2GU4 A;  5JHU A;  4R60 A;  2BB7 A;  4U6W A;  2BWW A;  4U71 A;  5JFR A;  1JAW A;  3Q6D A;  2OAZ A;  1B6A A;  1XGM A;  2BWT A;  2IW2 A;  5JI6 A;  1QXZ A;  4ZWO A;  4IKR A;  2BWY A;  1A16 A;  1M35 A;  1N51 A;  2BWS A;  4U1B A;  2BWX A;  4A6W A;  1YJ3 A;  3BIQ A;  2NQ6 A;  1WLR A;  4OOK A;  2GG0 A;  2MAT A;  2OKN A;  5CNX A;  1WL9 A;  4FLJ A;  2BWV A;  1PV9 A;  2BH3 A;  4FLK A;  1W7V A;  2BN7 A;  3PKC A;  3S6B A;  2Q94 A;  2GG7 A;  5CDV A;  3IU8 A;  3PKB A;  3RVA A;  4U6Z A;  1W2M A;  1XGS A;  4ZNG A;  2GG5 A;  2ZSG A;  3FM3 A;  2GG3 A;  3IU9 A;  2GG9 A;  3L7G A;  1YW9 A;  4IKU A;  3CB5 A;  4FKC A;  4IKT A;  3CTZ A;  4IKS A;  5CIK A;  2BWU A;  1B59 A;  4U70 A;  4HXX A;  1WL6 A;  1O0X A;  2GGC A;  4IEC A;  4FO8 A;  5CDE A;  2BHD A;  2HOW A;  2Q93 A;  4RGZ 1;  2BHA A;  3MAT A;  1WY2 A;  1BN5 A;  3MX6 A;  3PKE A;  5FCH A;  1C24 A;  3L24 A;  1Y1N A;  1KQ0 A;  2G6P A;  2P98 A;  4FUK A;  2V6C A;  1XNZ A;  4PV4 A;  1MAT A;  2Q8K A;  2B3L A;  3D27 A;  1C27 A;  1YVM A;  4FO7 A;  4IF7 A;  2V3Z A;  4EGE A;  4MAT A;  4IDY A;  5CLS A;  1KQ9 A;  2ADU A;  1YW7 A;  3MR1 A;  3FMR A;  1C23 A;  2EA2 A;  2EA4 A;  2P99 A;  1C21 A;  1YW8 A;  4U6E A;  4RZZ A;  3CB6 A;  2BHC A;  4IU6 A;  2B3H A;  3PKD A;  2GU6 A;  2GG2 A;  4ZWP A;  2GU5 A;  4S2R P;  5E5B A;  2V3X A;  3BIT A;  2NQ7 A;  4ZWU A;  4RZY A;  4U75 A; 
#chains in the Genus database with same CATH homology
 1WKM A;  2EVO A;  5D6E A;  1C22 A;  5D6F A;  4Z7M A;  1CHM A;  4FLL A;  4QR8 A;  1QXY A;  1R5G A;  4U73 A;  3PKA A;  4JUQ A;  4S01 A;  1WBQ A;  3FMQ A;  1QZY A;  4FLI A;  4A6V A;  4S2T P;  4U6C A;  2V3Y A;  3BIP A;  1R5H A;  2GTX A;  2P9A A;  1QXW A;  4S00 A;  1KP0 A;  4PNC A;  2GU7 A;  4KM3 A;  1XGO A;  4IPA A;  5CDL A;  2Q96 A;  3ROR A;  3TAV A;  2Q95 A;  4U69 A;  2BHB A;  1R58 A;  4U76 A;  5CE6 A;  4U6J A;  2Q92 A;  2DFI A;  2GG8 A;  3IU7 A;  2EVC A;  1XGN A;  2EVM A;  3TB5 A;  2B3K A;  2GGB A;  3IG4 A;  1BOA A;  2GZ5 A;  4B28 A;  5FCF A;  2GA2 A;  1WN1 A;  2GU4 A;  5JHU A;  4R60 A;  2BB7 A;  4U6W A;  2BWW A;  4U71 A;  5JFR A;  1JAW A;  3Q6D A;  2OAZ A;  1B6A A;  1XGM A;  2BWT A;  2IW2 A;  5JI6 A;  1QXZ A;  4ZWO A;  4IKR A;  2BWY A;  1A16 A;  1M35 A;  1N51 A;  2BWS A;  4U1B A;  2BWX A;  4A6W A;  1YJ3 A;  3BIQ A;  2NQ6 A;  1WLR A;  4OOK A;  2GG0 A;  2MAT A;  2OKN A;  5CNX A;  1WL9 A;  4FLJ A;  2BWV A;  1PV9 A;  2BH3 A;  4FLK A;  1W7V A;  2BN7 A;  3PKC A;  3S6B A;  2Q94 A;  2GG7 A;  5CDV A;  3IU8 A;  3PKB A;  3RVA A;  4U6Z A;  1W2M A;  1XGS A;  4ZNG A;  2GG5 A;  2ZSG A;  3FM3 A;  2GG3 A;  3IU9 A;  2GG9 A;  3L7G A;  1YW9 A;  4IKU A;  3CB5 A;  4FKC A;  4IKT A;  3CTZ A;  4IKS A;  5CIK A;  2BWU A;  1B59 A;  4U70 A;  4HXX A;  1WL6 A;  1O0X A;  2GGC A;  4IEC A;  4FO8 A;  5CDE A;  2BHD A;  2HOW A;  2Q93 A;  4RGZ 1;  2BHA A;  3MAT A;  1WY2 A;  1BN5 A;  3MX6 A;  3PKE A;  5FCH A;  1C24 A;  3L24 A;  1Y1N A;  1KQ0 A;  2G6P A;  2P98 A;  4FUK A;  2V6C A;  1XNZ A;  4PV4 A;  1MAT A;  2Q8K A;  2B3L A;  3D27 A;  1C27 A;  1YVM A;  4FO7 A;  4IF7 A;  2V3Z A;  4EGE A;  4MAT A;  4IDY A;  5CLS A;  1KQ9 A;  2ADU A;  1YW7 A;  3MR1 A;  3FMR A;  1C23 A;  2EA2 A;  2EA4 A;  2P99 A;  1C21 A;  1YW8 A;  4U6E A;  4RZZ A;  3CB6 A;  2BHC A;  4IU6 A;  2B3H A;  3PKD A;  2GU6 A;  2GG2 A;  4ZWP A;  2GU5 A;  4S2R P;  5E5B A;  2V3X A;  3BIT A;  2NQ7 A;  4ZWU A;  4RZY A;  4U75 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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