3RORA

Crystal structure of c105s mutant of mycobacterium tuberculosis methionine aminopeptidase
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCSTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3rorA01
2BHDA 2BHCA 2GGCA 2GG8A 3PKEA 1B59A 3Q6DA 4FLLA 4KM3A 2EVCA 5CLSA 4FO7A 1WN1A 1A16A 2GU7A 4A6VA 2EVMA 4IKTA 4S2TP 1XGNA 1C24A 4JUQA 4OOKA 4U76A 3L7GA 4IDYA 5D6FA 1R5GA 4FLIA 2G6PA 1XNZA 4U6JA 4U71A 1QZYA 1WL6A 4RGZ1 2B3HA 1XGMA 2BB7A 3CB5A 4IKSA 2GG9A 2ZSGA 1W7VA 5CNXA 5FCHA 4R60A 2NQ6A 2NQ7A 3IG4A 4IKRA 1MATA 3CTZA 3TB5A 4FLJA 2EA2A 2P99A 2IW2A 2OAZA 4HXXA 3IU9A 4U6WA 2Q96A 4U69A 1W2MA 3IU7A 1M35A 2B3KA 4U6ZA 2GGBA 1XGSA 4ZWOA 5JFRA 4FO8A 2BWYA 5JHUA 3FMQA 2Q95A 4PV4A 4MATA 1JAWA 2EVOA 2GU6A 5E5BA 1O0XA 1YW9A 2V3XA 4ZWPA 3FMRA 2P98A 1N51A 4ZWUA 4B28A 3MX6A 5CDVA 5CDLA 2P9AA 3PKAA 2BHBA 1BN5A 4IKUA 3PKDA 3MATA 2V3ZA 5FCFA 2V3YA 3TAVA 1QXYA 2ADUA 4U73A 2Q92A 2BWUA 1CHMA 2MATA 4IPAA 2GG7A 1C27A 2GTXA 2HOWA 3MR1A 1XGOA 4U1BA 1QXZA 3L24A 4U75A 4A6WA 1WBQA 4S2RP 2BWXA 4FLKA 3S6BA 1YW8A 2DFIA 2GG3A 2OKNA 1C23A 3BIQA 3BITA 1R5HA 1B6AA 2GA2A 3FM3A 1QXWA 4U70A 2GG5A 4Z7MA 3CB6A 1YJ3A 5JI6A 1YW7A 1C21A 2BWTA 4RZZA 5CDEA 4U6EA 5CIKA 4EGEA 4S00A 4FUKA 1WL9A 2GG0A 4ZNGA 2BWWA 4U6CA 1R58A 4S01A 2V6CA 1YVMA 1PV9A 2BN7A 3BIPA 4PNCA 3RORA 5CE6A 3IU8A 5D6EA 1BOAA 2EA4A 1Y1NA 1KQ0A 2B3LA 2GZ5A 2BH3A 3D27A 4QR8A 2GU5A 1WLRA 3RVAA 3PKBA 4IU6A 2BHAA 1KP0A 1KQ9A 2Q94A 2GU4A 2Q93A 1WKMA 4IF7A 1WY2A 2BWVA 2GG2A 2BWSA 4FKCA 4IECA 2Q8KA 3PKCA 1C22A 4RZYA
chains in the Genus database with same CATH superfamily
2BHDA 2BHCA 2GGCA 2GG8A 3PKEA 1B59A 3Q6DA 4FLLA 4KM3A 2EVCA 5CLSA 4FO7A 1WN1A 1A16A 2GU7A 4A6VA 2EVMA 4IKTA 4S2TP 1XGNA 1C24A 4JUQA 4OOKA 4U76A 3L7GA 4IDYA 5D6FA 1R5GA 4FLIA 2G6PA 1XNZA 4U6JA 4U71A 1QZYA 1WL6A 4RGZ1 2B3HA 1XGMA 2BB7A 3CB5A 4IKSA 2GG9A 2ZSGA 1W7VA 5CNXA 5FCHA 4R60A 2NQ6A 2NQ7A 3IG4A 4IKRA 1MATA 3CTZA 3TB5A 4FLJA 2EA2A 2P99A 2IW2A 2OAZA 4HXXA 3IU9A 4U6WA 2Q96A 4U69A 1W2MA 3IU7A 1M35A 2B3KA 4U6ZA 2GGBA 1XGSA 4ZWOA 5JFRA 4FO8A 2BWYA 5JHUA 3FMQA 2Q95A 4PV4A 4MATA 1JAWA 2EVOA 2GU6A 5E5BA 1O0XA 1YW9A 2V3XA 4ZWPA 3FMRA 2P98A 1N51A 4ZWUA 4B28A 3MX6A 5CDVA 5CDLA 2P9AA 3PKAA 2BHBA 1BN5A 4IKUA 3PKDA 3MATA 2V3ZA 5FCFA 2V3YA 3TAVA 1QXYA 2ADUA 4U73A 2Q92A 2BWUA 1CHMA 2MATA 4IPAA 2GG7A 1C27A 2GTXA 2HOWA 3MR1A 1XGOA 4U1BA 1QXZA 3L24A 4U75A 4A6WA 1WBQA 4S2RP 2BWXA 4FLKA 3S6BA 1YW8A 2DFIA 2GG3A 2OKNA 1C23A 3BIQA 3BITA 1R5HA 1B6AA 2GA2A 3FM3A 1QXWA 4U70A 2GG5A 4Z7MA 3CB6A 1YJ3A 5JI6A 1YW7A 1C21A 2BWTA 4RZZA 5CDEA 4U6EA 5CIKA 4EGEA 4S00A 4FUKA 1WL9A 2GG0A 4ZNGA 2BWWA 4U6CA 1R58A 4S01A 2V6CA 1YVMA 1PV9A 2BN7A 3BIPA 4PNCA 3RORA 5CE6A 3IU8A 5D6EA 1BOAA 2EA4A 1Y1NA 1KQ0A 2B3LA 2GZ5A 2BH3A 3D27A 4QR8A 2GU5A 1WLRA 3RVAA 3PKBA 4IU6A 2BHAA 1KP0A 1KQ9A 2Q94A 2GU4A 2Q93A 1WKMA 4IF7A 1WY2A 2BWVA 2GG2A 2BWSA 4FKCA 4IECA 2Q8KA 3PKCA 1C22A 4RZYA
chains in the Genus database with same CATH topology
2BHDA 2BHCA 2GGCA 2GG8A 3PKEA 1B59A 3Q6DA 4FLLA 4KM3A 2EVCA 5CLSA 4FO7A 1WN1A 1A16A 2GU7A 4A6VA 2EVMA 4IKTA 4S2TP 1XGNA 1C24A 4JUQA 4OOKA 4U76A 3L7GA 4IDYA 5D6FA 1R5GA 4FLIA 2G6PA 1XNZA 4U6JA 4U71A 1QZYA 1WL6A 4RGZ1 2B3HA 1XGMA 2BB7A 3CB5A 4IKSA 2GG9A 2ZSGA 1W7VA 5CNXA 5FCHA 4R60A 2NQ6A 2NQ7A 3IG4A 4IKRA 1MATA 3CTZA 3TB5A 4FLJA 2EA2A 2P99A 2IW2A 2OAZA 4HXXA 3IU9A 4U6WA 2Q96A 4U69A 1W2MA 3IU7A 1M35A 2B3KA 4U6ZA 2GGBA 1XGSA 4ZWOA 5JFRA 4FO8A 2BWYA 5JHUA 3FMQA 2Q95A 4PV4A 4MATA 1JAWA 2EVOA 2GU6A 5E5BA 1O0XA 1YW9A 2V3XA 4ZWPA 3FMRA 2P98A 1N51A 4ZWUA 4B28A 3MX6A 5CDVA 5CDLA 2P9AA 3PKAA 2BHBA 1BN5A 4IKUA 3PKDA 3MATA 2V3ZA 5FCFA 2V3YA 3TAVA 1QXYA 2ADUA 4U73A 2Q92A 2BWUA 1CHMA 2MATA 4IPAA 2GG7A 1C27A 2GTXA 2HOWA 3MR1A 1XGOA 4U1BA 1QXZA 3L24A 4U75A 4A6WA 1WBQA 4S2RP 2BWXA 4FLKA 3S6BA 1YW8A 2DFIA 2GG3A 2OKNA 1C23A 3BIQA 3BITA 1R5HA 1B6AA 2GA2A 3FM3A 1QXWA 4U70A 2GG5A 4Z7MA 3CB6A 1YJ3A 5JI6A 1YW7A 1C21A 2BWTA 4RZZA 5CDEA 4U6EA 5CIKA 4EGEA 4S00A 4FUKA 1WL9A 2GG0A 4ZNGA 2BWWA 4U6CA 1R58A 4S01A 2V6CA 1YVMA 1PV9A 2BN7A 3BIPA 4PNCA 3RORA 5CE6A 3IU8A 5D6EA 1BOAA 2EA4A 1Y1NA 1KQ0A 2B3LA 2GZ5A 2BH3A 3D27A 4QR8A 2GU5A 1WLRA 3RVAA 3PKBA 4IU6A 2BHAA 1KP0A 1KQ9A 2Q94A 2GU4A 2Q93A 1WKMA 4IF7A 1WY2A 2BWVA 2GG2A 2BWSA 4FKCA 4IECA 2Q8KA 3PKCA 1C22A 4RZYA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2BHD A;  2BHC A;  2GGC A;  2GG8 A;  3PKE A;  1B59 A;  3Q6D A;  4FLL A;  4KM3 A;  2EVC A;  5CLS A;  4FO7 A;  1WN1 A;  1A16 A;  2GU7 A;  4A6V A;  2EVM A;  4IKT A;  4S2T P;  1XGN A;  1C24 A;  4JUQ A;  4OOK A;  4U76 A;  3L7G A;  4IDY A;  5D6F A;  1R5G A;  4FLI A;  2G6P A;  1XNZ A;  4U6J A;  4U71 A;  1QZY A;  1WL6 A;  4RGZ 1;  2B3H A;  1XGM A;  2BB7 A;  3CB5 A;  4IKS A;  2GG9 A;  2ZSG A;  1W7V A;  5CNX A;  5FCH A;  4R60 A;  2NQ6 A;  2NQ7 A;  3IG4 A;  4IKR A;  1MAT A;  3CTZ A;  3TB5 A;  4FLJ A;  2EA2 A;  2P99 A;  2IW2 A;  2OAZ A;  4HXX A;  3IU9 A;  4U6W A;  2Q96 A;  4U69 A;  1W2M A;  3IU7 A;  1M35 A;  2B3K A;  4U6Z A;  2GGB A;  1XGS A;  4ZWO A;  5JFR A;  4FO8 A;  2BWY A;  5JHU A;  3FMQ A;  2Q95 A;  4PV4 A;  4MAT A;  1JAW A;  2EVO A;  2GU6 A;  5E5B A;  1O0X A;  1YW9 A;  2V3X A;  4ZWP A;  3FMR A;  2P98 A;  1N51 A;  4ZWU A;  4B28 A;  3MX6 A;  5CDV A;  5CDL A;  2P9A A;  3PKA A;  2BHB A;  1BN5 A;  4IKU A;  3PKD A;  3MAT A;  2V3Z A;  5FCF A;  2V3Y A;  3TAV A;  1QXY A;  2ADU A;  4U73 A;  2Q92 A;  2BWU A;  1CHM A;  2MAT A;  4IPA A;  2GG7 A;  1C27 A;  2GTX A;  2HOW A;  3MR1 A;  1XGO A;  4U1B A;  1QXZ A;  3L24 A;  4U75 A;  4A6W A;  1WBQ A;  4S2R P;  2BWX A;  4FLK A;  3S6B A;  1YW8 A;  2DFI A;  2GG3 A;  2OKN A;  1C23 A;  3BIQ A;  3BIT A;  1R5H A;  1B6A A;  2GA2 A;  3FM3 A;  1QXW A;  4U70 A;  2GG5 A;  4Z7M A;  3CB6 A;  1YJ3 A;  5JI6 A;  1YW7 A;  1C21 A;  2BWT A;  4RZZ A;  5CDE A;  4U6E A;  5CIK A;  4EGE A;  4S00 A;  4FUK A;  1WL9 A;  2GG0 A;  4ZNG A;  2BWW A;  4U6C A;  1R58 A;  4S01 A;  2V6C A;  1YVM A;  1PV9 A;  2BN7 A;  3BIP A;  4PNC A;  3ROR A;  5CE6 A;  3IU8 A;  5D6E A;  1BOA A;  2EA4 A;  1Y1N A;  1KQ0 A;  2B3L A;  2GZ5 A;  2BH3 A;  3D27 A;  4QR8 A;  2GU5 A;  1WLR A;  3RVA A;  3PKB A;  4IU6 A;  2BHA A;  1KP0 A;  1KQ9 A;  2Q94 A;  2GU4 A;  2Q93 A;  1WKM A;  4IF7 A;  1WY2 A;  2BWV A;  2GG2 A;  2BWS A;  4FKC A;  4IEC A;  2Q8K A;  3PKC A;  1C22 A;  4RZY A; 
#chains in the Genus database with same CATH topology
 2BHD A;  2BHC A;  2GGC A;  2GG8 A;  3PKE A;  1B59 A;  3Q6D A;  4FLL A;  4KM3 A;  2EVC A;  5CLS A;  4FO7 A;  1WN1 A;  1A16 A;  2GU7 A;  4A6V A;  2EVM A;  4IKT A;  4S2T P;  1XGN A;  1C24 A;  4JUQ A;  4OOK A;  4U76 A;  3L7G A;  4IDY A;  5D6F A;  1R5G A;  4FLI A;  2G6P A;  1XNZ A;  4U6J A;  4U71 A;  1QZY A;  1WL6 A;  4RGZ 1;  2B3H A;  1XGM A;  2BB7 A;  3CB5 A;  4IKS A;  2GG9 A;  2ZSG A;  1W7V A;  5CNX A;  5FCH A;  4R60 A;  2NQ6 A;  2NQ7 A;  3IG4 A;  4IKR A;  1MAT A;  3CTZ A;  3TB5 A;  4FLJ A;  2EA2 A;  2P99 A;  2IW2 A;  2OAZ A;  4HXX A;  3IU9 A;  4U6W A;  2Q96 A;  4U69 A;  1W2M A;  3IU7 A;  1M35 A;  2B3K A;  4U6Z A;  2GGB A;  1XGS A;  4ZWO A;  5JFR A;  4FO8 A;  2BWY A;  5JHU A;  3FMQ A;  2Q95 A;  4PV4 A;  4MAT A;  1JAW A;  2EVO A;  2GU6 A;  5E5B A;  1O0X A;  1YW9 A;  2V3X A;  4ZWP A;  3FMR A;  2P98 A;  1N51 A;  4ZWU A;  4B28 A;  3MX6 A;  5CDV A;  5CDL A;  2P9A A;  3PKA A;  2BHB A;  1BN5 A;  4IKU A;  3PKD A;  3MAT A;  2V3Z A;  5FCF A;  2V3Y A;  3TAV A;  1QXY A;  2ADU A;  4U73 A;  2Q92 A;  2BWU A;  1CHM A;  2MAT A;  4IPA A;  2GG7 A;  1C27 A;  2GTX A;  2HOW A;  3MR1 A;  1XGO A;  4U1B A;  1QXZ A;  3L24 A;  4U75 A;  4A6W A;  1WBQ A;  4S2R P;  2BWX A;  4FLK A;  3S6B A;  1YW8 A;  2DFI A;  2GG3 A;  2OKN A;  1C23 A;  3BIQ A;  3BIT A;  1R5H A;  1B6A A;  2GA2 A;  3FM3 A;  1QXW A;  4U70 A;  2GG5 A;  4Z7M A;  3CB6 A;  1YJ3 A;  5JI6 A;  1YW7 A;  1C21 A;  2BWT A;  4RZZ A;  5CDE A;  4U6E A;  5CIK A;  4EGE A;  4S00 A;  4FUK A;  1WL9 A;  2GG0 A;  4ZNG A;  2BWW A;  4U6C A;  1R58 A;  4S01 A;  2V6C A;  1YVM A;  1PV9 A;  2BN7 A;  3BIP A;  4PNC A;  3ROR A;  5CE6 A;  3IU8 A;  5D6E A;  1BOA A;  2EA4 A;  1Y1N A;  1KQ0 A;  2B3L A;  2GZ5 A;  2BH3 A;  3D27 A;  4QR8 A;  2GU5 A;  1WLR A;  3RVA A;  3PKB A;  4IU6 A;  2BHA A;  1KP0 A;  1KQ9 A;  2Q94 A;  2GU4 A;  2Q93 A;  1WKM A;  4IF7 A;  1WY2 A;  2BWV A;  2GG2 A;  2BWS A;  4FKC A;  4IEC A;  2Q8K A;  3PKC A;  1C22 A;  4RZY A; 
#chains in the Genus database with same CATH homology
 2BHD A;  2BHC A;  2GGC A;  2GG8 A;  3PKE A;  1B59 A;  3Q6D A;  4FLL A;  4KM3 A;  2EVC A;  5CLS A;  4FO7 A;  1WN1 A;  1A16 A;  2GU7 A;  4A6V A;  2EVM A;  4IKT A;  4S2T P;  1XGN A;  1C24 A;  4JUQ A;  4OOK A;  4U76 A;  3L7G A;  4IDY A;  5D6F A;  1R5G A;  4FLI A;  2G6P A;  1XNZ A;  4U6J A;  4U71 A;  1QZY A;  1WL6 A;  4RGZ 1;  2B3H A;  1XGM A;  2BB7 A;  3CB5 A;  4IKS A;  2GG9 A;  2ZSG A;  1W7V A;  5CNX A;  5FCH A;  4R60 A;  2NQ6 A;  2NQ7 A;  3IG4 A;  4IKR A;  1MAT A;  3CTZ A;  3TB5 A;  4FLJ A;  2EA2 A;  2P99 A;  2IW2 A;  2OAZ A;  4HXX A;  3IU9 A;  4U6W A;  2Q96 A;  4U69 A;  1W2M A;  3IU7 A;  1M35 A;  2B3K A;  4U6Z A;  2GGB A;  1XGS A;  4ZWO A;  5JFR A;  4FO8 A;  2BWY A;  5JHU A;  3FMQ A;  2Q95 A;  4PV4 A;  4MAT A;  1JAW A;  2EVO A;  2GU6 A;  5E5B A;  1O0X A;  1YW9 A;  2V3X A;  4ZWP A;  3FMR A;  2P98 A;  1N51 A;  4ZWU A;  4B28 A;  3MX6 A;  5CDV A;  5CDL A;  2P9A A;  3PKA A;  2BHB A;  1BN5 A;  4IKU A;  3PKD A;  3MAT A;  2V3Z A;  5FCF A;  2V3Y A;  3TAV A;  1QXY A;  2ADU A;  4U73 A;  2Q92 A;  2BWU A;  1CHM A;  2MAT A;  4IPA A;  2GG7 A;  1C27 A;  2GTX A;  2HOW A;  3MR1 A;  1XGO A;  4U1B A;  1QXZ A;  3L24 A;  4U75 A;  4A6W A;  1WBQ A;  4S2R P;  2BWX A;  4FLK A;  3S6B A;  1YW8 A;  2DFI A;  2GG3 A;  2OKN A;  1C23 A;  3BIQ A;  3BIT A;  1R5H A;  1B6A A;  2GA2 A;  3FM3 A;  1QXW A;  4U70 A;  2GG5 A;  4Z7M A;  3CB6 A;  1YJ3 A;  5JI6 A;  1YW7 A;  1C21 A;  2BWT A;  4RZZ A;  5CDE A;  4U6E A;  5CIK A;  4EGE A;  4S00 A;  4FUK A;  1WL9 A;  2GG0 A;  4ZNG A;  2BWW A;  4U6C A;  1R58 A;  4S01 A;  2V6C A;  1YVM A;  1PV9 A;  2BN7 A;  3BIP A;  4PNC A;  3ROR A;  5CE6 A;  3IU8 A;  5D6E A;  1BOA A;  2EA4 A;  1Y1N A;  1KQ0 A;  2B3L A;  2GZ5 A;  2BH3 A;  3D27 A;  4QR8 A;  2GU5 A;  1WLR A;  3RVA A;  3PKB A;  4IU6 A;  2BHA A;  1KP0 A;  1KQ9 A;  2Q94 A;  2GU4 A;  2Q93 A;  1WKM A;  4IF7 A;  1WY2 A;  2BWV A;  2GG2 A;  2BWS A;  4FKC A;  4IEC A;  2Q8K A;  3PKC A;  1C22 A;  4RZY A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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