3RORA

Crystal structure of c105s mutant of mycobacterium tuberculosis methionine aminopeptidase
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCSTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
rcsb
source organism Mycobacterium tuberculosis
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3rorA01
4Z7MA 4U73A 2Q96A 4HXXA 2GG5A 1Y1NA 2NQ7A 4A6WA 2P99A 4IDYA 5E5BA 2EA2A 5CDVA 2Q8KA 3L7GA 1WN1A 2GU7A 2P98A 1C21A 4S01A 2BHAA 1M35A 2GG2A 2G6PA 1JAWA 2BWSA 1N51A 2GG8A 3MR1A 2B3HA 4IKTA 4PV4A 2B3LA 1QXYA 5CDLA 1B6AA 2NQ6A 2Q94A 4RZYA 2ADUA 2Q93A 1PV9A 1R5HA 3RVAA 4ZWOA 2GZ5A 1YW9A 1KQ0A 1QXZA 4FLLA 1YW7A 3BITA 1XGMA 3D27A 4U75A 1C24A 2GG9A 4KM3A 4U69A 1A16A 3MX6A 1WKMA 2BWYA 3Q6DA 4OOKA 4U6CA 5JHUA 2BWXA 5CLSA 4IECA 2OKNA 3FM3A 1WY2A 3CTZA 2IW2A 3FMRA 4S2TP 4U6WA 3IU8A 2MATA 1R58A 3CB5A 1CHMA 2GG3A 2ZSGA 2EVCA 4R60A 2EVMA 1MATA 4IU6A 2EA4A 4IKSA 4FLKA 2BWWA 4U71A 3PKAA 4FUKA 3IU7A 1XNZA 1XGOA 3MATA 1W2MA 1WL6A 3PKCA 4ZWPA 2BHCA 1C27A 2BWTA 2V3ZA 1C23A 4B28A 1QZYA 2BN7A 4PNCA 1QXWA 1YW8A 5JI6A 2Q92A 2GTXA 2GGCA 2B3KA 2BH3A 4U76A 3PKEA 2BHBA 3PKDA 4FLJA 1C22A 1WBQA 4S2RP 1B59A 4U6EA 2GU6A 2BWUA 1XGSA 3FMQA 4FKCA 1WL9A 3L24A 3RORA 4FO8A 2GG7A 4U70A 2OAZA 5D6FA 1O0XA 5CDEA 4IF7A 5JFRA 5D6EA 2EVOA 4FLIA 5CE6A 1BOAA 2BB7A 1R5GA 2V6CA 3S6BA 4ZWUA 2DFIA 4IPAA 2BHDA 4U6ZA 1W7VA 2V3XA 4EGEA 1YVMA 5CIKA 2HOWA 4RZZA 3TB5A 4S00A 3CB6A 3PKBA 5CNXA 3BIQA 4JUQA 1XGNA 2V3YA 2GU4A 2Q95A 4ZNGA 2GA2A 4U1BA 1KQ9A 1YJ3A 4A6VA 2P9AA 2GG0A 2GGBA 4QR8A 4U6JA 1BN5A 4MATA 4RGZ1 3IG4A 4FO7A 4IKRA 5FCHA 3TAVA 5FCFA 1KP0A 4IKUA 2BWVA 3IU9A 2GU5A 1WLRA 3BIPA
chains in the Genus database with same CATH superfamily
4Z7MA 4U73A 2Q96A 4HXXA 2GG5A 1Y1NA 2NQ7A 4A6WA 2P99A 4IDYA 5E5BA 2EA2A 5CDVA 2Q8KA 3L7GA 1WN1A 2GU7A 2P98A 1C21A 4S01A 2BHAA 1M35A 2GG2A 2G6PA 1JAWA 2BWSA 1N51A 2GG8A 3MR1A 2B3HA 4IKTA 4PV4A 2B3LA 1QXYA 5CDLA 1B6AA 2NQ6A 2Q94A 4RZYA 2ADUA 2Q93A 1PV9A 1R5HA 3RVAA 4ZWOA 2GZ5A 1YW9A 1KQ0A 1QXZA 4FLLA 1YW7A 3BITA 1XGMA 3D27A 4U75A 1C24A 2GG9A 4KM3A 4U69A 1A16A 3MX6A 1WKMA 2BWYA 3Q6DA 4OOKA 4U6CA 5JHUA 2BWXA 5CLSA 4IECA 2OKNA 3FM3A 1WY2A 3CTZA 2IW2A 3FMRA 4S2TP 4U6WA 3IU8A 2MATA 1R58A 3CB5A 1CHMA 2GG3A 2ZSGA 2EVCA 4R60A 2EVMA 1MATA 4IU6A 2EA4A 4IKSA 4FLKA 2BWWA 4U71A 3PKAA 4FUKA 3IU7A 1XNZA 1XGOA 3MATA 1W2MA 1WL6A 3PKCA 4ZWPA 2BHCA 1C27A 2BWTA 2V3ZA 1C23A 4B28A 1QZYA 2BN7A 4PNCA 1QXWA 1YW8A 5JI6A 2Q92A 2GTXA 2GGCA 2B3KA 2BH3A 4U76A 3PKEA 2BHBA 3PKDA 4FLJA 1C22A 1WBQA 4S2RP 1B59A 4U6EA 2GU6A 2BWUA 1XGSA 3FMQA 4FKCA 1WL9A 3L24A 3RORA 4FO8A 2GG7A 4U70A 2OAZA 5D6FA 1O0XA 5CDEA 4IF7A 5JFRA 5D6EA 2EVOA 4FLIA 5CE6A 1BOAA 2BB7A 1R5GA 2V6CA 3S6BA 4ZWUA 2DFIA 4IPAA 2BHDA 4U6ZA 1W7VA 2V3XA 4EGEA 1YVMA 5CIKA 2HOWA 4RZZA 3TB5A 4S00A 3CB6A 3PKBA 5CNXA 3BIQA 4JUQA 1XGNA 2V3YA 2GU4A 2Q95A 4ZNGA 2GA2A 4U1BA 1KQ9A 1YJ3A 4A6VA 2P9AA 2GG0A 2GGBA 4QR8A 4U6JA 1BN5A 4MATA 4RGZ1 3IG4A 4FO7A 4IKRA 5FCHA 3TAVA 5FCFA 1KP0A 4IKUA 2BWVA 3IU9A 2GU5A 1WLRA 3BIPA
chains in the Genus database with same CATH topology
4Z7MA 4U73A 2Q96A 4HXXA 2GG5A 1Y1NA 2NQ7A 4A6WA 2P99A 4IDYA 5E5BA 2EA2A 5CDVA 2Q8KA 3L7GA 1WN1A 2GU7A 2P98A 1C21A 4S01A 2BHAA 1M35A 2GG2A 2G6PA 1JAWA 2BWSA 1N51A 2GG8A 3MR1A 2B3HA 4IKTA 4PV4A 2B3LA 1QXYA 5CDLA 1B6AA 2NQ6A 2Q94A 4RZYA 2ADUA 2Q93A 1PV9A 1R5HA 3RVAA 4ZWOA 2GZ5A 1YW9A 1KQ0A 1QXZA 4FLLA 1YW7A 3BITA 1XGMA 3D27A 4U75A 1C24A 2GG9A 4KM3A 4U69A 1A16A 3MX6A 1WKMA 2BWYA 3Q6DA 4OOKA 4U6CA 5JHUA 2BWXA 5CLSA 4IECA 2OKNA 3FM3A 1WY2A 3CTZA 2IW2A 3FMRA 4S2TP 4U6WA 3IU8A 2MATA 1R58A 3CB5A 1CHMA 2GG3A 2ZSGA 2EVCA 4R60A 2EVMA 1MATA 4IU6A 2EA4A 4IKSA 4FLKA 2BWWA 4U71A 3PKAA 4FUKA 3IU7A 1XNZA 1XGOA 3MATA 1W2MA 1WL6A 3PKCA 4ZWPA 2BHCA 1C27A 2BWTA 2V3ZA 1C23A 4B28A 1QZYA 2BN7A 4PNCA 1QXWA 1YW8A 5JI6A 2Q92A 2GTXA 2GGCA 2B3KA 2BH3A 4U76A 3PKEA 2BHBA 3PKDA 4FLJA 1C22A 1WBQA 4S2RP 1B59A 4U6EA 2GU6A 2BWUA 1XGSA 3FMQA 4FKCA 1WL9A 3L24A 3RORA 4FO8A 2GG7A 4U70A 2OAZA 5D6FA 1O0XA 5CDEA 4IF7A 5JFRA 5D6EA 2EVOA 4FLIA 5CE6A 1BOAA 2BB7A 1R5GA 2V6CA 3S6BA 4ZWUA 2DFIA 4IPAA 2BHDA 4U6ZA 1W7VA 2V3XA 4EGEA 1YVMA 5CIKA 2HOWA 4RZZA 3TB5A 4S00A 3CB6A 3PKBA 5CNXA 3BIQA 4JUQA 1XGNA 2V3YA 2GU4A 2Q95A 4ZNGA 2GA2A 4U1BA 1KQ9A 1YJ3A 4A6VA 2P9AA 2GG0A 2GGBA 4QR8A 4U6JA 1BN5A 4MATA 4RGZ1 3IG4A 4FO7A 4IKRA 5FCHA 3TAVA 5FCFA 1KP0A 4IKUA 2BWVA 3IU9A 2GU5A 1WLRA 3BIPA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4Z7M A;  4U73 A;  2Q96 A;  4HXX A;  2GG5 A;  1Y1N A;  2NQ7 A;  4A6W A;  2P99 A;  4IDY A;  5E5B A;  2EA2 A;  5CDV A;  2Q8K A;  3L7G A;  1WN1 A;  2GU7 A;  2P98 A;  1C21 A;  4S01 A;  2BHA A;  1M35 A;  2GG2 A;  2G6P A;  1JAW A;  2BWS A;  1N51 A;  2GG8 A;  3MR1 A;  2B3H A;  4IKT A;  4PV4 A;  2B3L A;  1QXY A;  5CDL A;  1B6A A;  2NQ6 A;  2Q94 A;  4RZY A;  2ADU A;  2Q93 A;  1PV9 A;  1R5H A;  3RVA A;  4ZWO A;  2GZ5 A;  1YW9 A;  1KQ0 A;  1QXZ A;  4FLL A;  1YW7 A;  3BIT A;  1XGM A;  3D27 A;  4U75 A;  1C24 A;  2GG9 A;  4KM3 A;  4U69 A;  1A16 A;  3MX6 A;  1WKM A;  2BWY A;  3Q6D A;  4OOK A;  4U6C A;  5JHU A;  2BWX A;  5CLS A;  4IEC A;  2OKN A;  3FM3 A;  1WY2 A;  3CTZ A;  2IW2 A;  3FMR A;  4S2T P;  4U6W A;  3IU8 A;  2MAT A;  1R58 A;  3CB5 A;  1CHM A;  2GG3 A;  2ZSG A;  2EVC A;  4R60 A;  2EVM A;  1MAT A;  4IU6 A;  2EA4 A;  4IKS A;  4FLK A;  2BWW A;  4U71 A;  3PKA A;  4FUK A;  3IU7 A;  1XNZ A;  1XGO A;  3MAT A;  1W2M A;  1WL6 A;  3PKC A;  4ZWP A;  2BHC A;  1C27 A;  2BWT A;  2V3Z A;  1C23 A;  4B28 A;  1QZY A;  2BN7 A;  4PNC A;  1QXW A;  1YW8 A;  5JI6 A;  2Q92 A;  2GTX A;  2GGC A;  2B3K A;  2BH3 A;  4U76 A;  3PKE A;  2BHB A;  3PKD A;  4FLJ A;  1C22 A;  1WBQ A;  4S2R P;  1B59 A;  4U6E A;  2GU6 A;  2BWU A;  1XGS A;  3FMQ A;  4FKC A;  1WL9 A;  3L24 A;  3ROR A;  4FO8 A;  2GG7 A;  4U70 A;  2OAZ A;  5D6F A;  1O0X A;  5CDE A;  4IF7 A;  5JFR A;  5D6E A;  2EVO A;  4FLI A;  5CE6 A;  1BOA A;  2BB7 A;  1R5G A;  2V6C A;  3S6B A;  4ZWU A;  2DFI A;  4IPA A;  2BHD A;  4U6Z A;  1W7V A;  2V3X A;  4EGE A;  1YVM A;  5CIK A;  2HOW A;  4RZZ A;  3TB5 A;  4S00 A;  3CB6 A;  3PKB A;  5CNX A;  3BIQ A;  4JUQ A;  1XGN A;  2V3Y A;  2GU4 A;  2Q95 A;  4ZNG A;  2GA2 A;  4U1B A;  1KQ9 A;  1YJ3 A;  4A6V A;  2P9A A;  2GG0 A;  2GGB A;  4QR8 A;  4U6J A;  1BN5 A;  4MAT A;  4RGZ 1;  3IG4 A;  4FO7 A;  4IKR A;  5FCH A;  3TAV A;  5FCF A;  1KP0 A;  4IKU A;  2BWV A;  3IU9 A;  2GU5 A;  1WLR A;  3BIP A; 
#chains in the Genus database with same CATH topology
 4Z7M A;  4U73 A;  2Q96 A;  4HXX A;  2GG5 A;  1Y1N A;  2NQ7 A;  4A6W A;  2P99 A;  4IDY A;  5E5B A;  2EA2 A;  5CDV A;  2Q8K A;  3L7G A;  1WN1 A;  2GU7 A;  2P98 A;  1C21 A;  4S01 A;  2BHA A;  1M35 A;  2GG2 A;  2G6P A;  1JAW A;  2BWS A;  1N51 A;  2GG8 A;  3MR1 A;  2B3H A;  4IKT A;  4PV4 A;  2B3L A;  1QXY A;  5CDL A;  1B6A A;  2NQ6 A;  2Q94 A;  4RZY A;  2ADU A;  2Q93 A;  1PV9 A;  1R5H A;  3RVA A;  4ZWO A;  2GZ5 A;  1YW9 A;  1KQ0 A;  1QXZ A;  4FLL A;  1YW7 A;  3BIT A;  1XGM A;  3D27 A;  4U75 A;  1C24 A;  2GG9 A;  4KM3 A;  4U69 A;  1A16 A;  3MX6 A;  1WKM A;  2BWY A;  3Q6D A;  4OOK A;  4U6C A;  5JHU A;  2BWX A;  5CLS A;  4IEC A;  2OKN A;  3FM3 A;  1WY2 A;  3CTZ A;  2IW2 A;  3FMR A;  4S2T P;  4U6W A;  3IU8 A;  2MAT A;  1R58 A;  3CB5 A;  1CHM A;  2GG3 A;  2ZSG A;  2EVC A;  4R60 A;  2EVM A;  1MAT A;  4IU6 A;  2EA4 A;  4IKS A;  4FLK A;  2BWW A;  4U71 A;  3PKA A;  4FUK A;  3IU7 A;  1XNZ A;  1XGO A;  3MAT A;  1W2M A;  1WL6 A;  3PKC A;  4ZWP A;  2BHC A;  1C27 A;  2BWT A;  2V3Z A;  1C23 A;  4B28 A;  1QZY A;  2BN7 A;  4PNC A;  1QXW A;  1YW8 A;  5JI6 A;  2Q92 A;  2GTX A;  2GGC A;  2B3K A;  2BH3 A;  4U76 A;  3PKE A;  2BHB A;  3PKD A;  4FLJ A;  1C22 A;  1WBQ A;  4S2R P;  1B59 A;  4U6E A;  2GU6 A;  2BWU A;  1XGS A;  3FMQ A;  4FKC A;  1WL9 A;  3L24 A;  3ROR A;  4FO8 A;  2GG7 A;  4U70 A;  2OAZ A;  5D6F A;  1O0X A;  5CDE A;  4IF7 A;  5JFR A;  5D6E A;  2EVO A;  4FLI A;  5CE6 A;  1BOA A;  2BB7 A;  1R5G A;  2V6C A;  3S6B A;  4ZWU A;  2DFI A;  4IPA A;  2BHD A;  4U6Z A;  1W7V A;  2V3X A;  4EGE A;  1YVM A;  5CIK A;  2HOW A;  4RZZ A;  3TB5 A;  4S00 A;  3CB6 A;  3PKB A;  5CNX A;  3BIQ A;  4JUQ A;  1XGN A;  2V3Y A;  2GU4 A;  2Q95 A;  4ZNG A;  2GA2 A;  4U1B A;  1KQ9 A;  1YJ3 A;  4A6V A;  2P9A A;  2GG0 A;  2GGB A;  4QR8 A;  4U6J A;  1BN5 A;  4MAT A;  4RGZ 1;  3IG4 A;  4FO7 A;  4IKR A;  5FCH A;  3TAV A;  5FCF A;  1KP0 A;  4IKU A;  2BWV A;  3IU9 A;  2GU5 A;  1WLR A;  3BIP A; 
#chains in the Genus database with same CATH homology
 4Z7M A;  4U73 A;  2Q96 A;  4HXX A;  2GG5 A;  1Y1N A;  2NQ7 A;  4A6W A;  2P99 A;  4IDY A;  5E5B A;  2EA2 A;  5CDV A;  2Q8K A;  3L7G A;  1WN1 A;  2GU7 A;  2P98 A;  1C21 A;  4S01 A;  2BHA A;  1M35 A;  2GG2 A;  2G6P A;  1JAW A;  2BWS A;  1N51 A;  2GG8 A;  3MR1 A;  2B3H A;  4IKT A;  4PV4 A;  2B3L A;  1QXY A;  5CDL A;  1B6A A;  2NQ6 A;  2Q94 A;  4RZY A;  2ADU A;  2Q93 A;  1PV9 A;  1R5H A;  3RVA A;  4ZWO A;  2GZ5 A;  1YW9 A;  1KQ0 A;  1QXZ A;  4FLL A;  1YW7 A;  3BIT A;  1XGM A;  3D27 A;  4U75 A;  1C24 A;  2GG9 A;  4KM3 A;  4U69 A;  1A16 A;  3MX6 A;  1WKM A;  2BWY A;  3Q6D A;  4OOK A;  4U6C A;  5JHU A;  2BWX A;  5CLS A;  4IEC A;  2OKN A;  3FM3 A;  1WY2 A;  3CTZ A;  2IW2 A;  3FMR A;  4S2T P;  4U6W A;  3IU8 A;  2MAT A;  1R58 A;  3CB5 A;  1CHM A;  2GG3 A;  2ZSG A;  2EVC A;  4R60 A;  2EVM A;  1MAT A;  4IU6 A;  2EA4 A;  4IKS A;  4FLK A;  2BWW A;  4U71 A;  3PKA A;  4FUK A;  3IU7 A;  1XNZ A;  1XGO A;  3MAT A;  1W2M A;  1WL6 A;  3PKC A;  4ZWP A;  2BHC A;  1C27 A;  2BWT A;  2V3Z A;  1C23 A;  4B28 A;  1QZY A;  2BN7 A;  4PNC A;  1QXW A;  1YW8 A;  5JI6 A;  2Q92 A;  2GTX A;  2GGC A;  2B3K A;  2BH3 A;  4U76 A;  3PKE A;  2BHB A;  3PKD A;  4FLJ A;  1C22 A;  1WBQ A;  4S2R P;  1B59 A;  4U6E A;  2GU6 A;  2BWU A;  1XGS A;  3FMQ A;  4FKC A;  1WL9 A;  3L24 A;  3ROR A;  4FO8 A;  2GG7 A;  4U70 A;  2OAZ A;  5D6F A;  1O0X A;  5CDE A;  4IF7 A;  5JFR A;  5D6E A;  2EVO A;  4FLI A;  5CE6 A;  1BOA A;  2BB7 A;  1R5G A;  2V6C A;  3S6B A;  4ZWU A;  2DFI A;  4IPA A;  2BHD A;  4U6Z A;  1W7V A;  2V3X A;  4EGE A;  1YVM A;  5CIK A;  2HOW A;  4RZZ A;  3TB5 A;  4S00 A;  3CB6 A;  3PKB A;  5CNX A;  3BIQ A;  4JUQ A;  1XGN A;  2V3Y A;  2GU4 A;  2Q95 A;  4ZNG A;  2GA2 A;  4U1B A;  1KQ9 A;  1YJ3 A;  4A6V A;  2P9A A;  2GG0 A;  2GGB A;  4QR8 A;  4U6J A;  1BN5 A;  4MAT A;  4RGZ 1;  3IG4 A;  4FO7 A;  4IKR A;  5FCH A;  3TAV A;  5FCF A;  1KP0 A;  4IKU A;  2BWV A;  3IU9 A;  2GU5 A;  1WLR A;  3BIP A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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