3RORA

Crystal structure of c105s mutant of mycobacterium tuberculosis methionine aminopeptidase
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCSTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3rorA01
3CB5A 1C24A 4U73A 1R5GA 2BWVA 2BH3A 2BN7A 1WY2A 2BHAA 2BB7A 3Q6DA 1R58A 4IECA 3FMRA 4PV4A 3S6BA 2NQ6A 5CIKA 1WN1A 2Q93A 4IPAA 2V3XA 2ADUA 3CB6A 1W2MA 2P9AA 1C22A 4U70A 4IF7A 1CHMA 2GGBA 3IG4A 1A16A 3MATA 5D6EA 5FCHA 4IKUA 1XGOA 2IW2A 1XGMA 4U69A 3IU8A 1B6AA 2BWTA 4EGEA 1MATA 4OOKA 1QXWA 2BWSA 2HOWA 4FO7A 5CNXA 4Z7MA 1YVMA 2ZSGA 3IU9A 3BIPA 1N51A 4HXXA 2GG5A 2GG0A 2Q95A 4S00A 1JAWA 4MATA 1WL9A 3BITA 4ZWPA 4U1BA 2GG2A 2EA2A 5CE6A 2NQ7A 2GG3A 3D27A 4IKRA 3RVAA 2EVCA 2OKNA 1WBQA 2BWWA 2GU6A 2EVMA 2V6CA 1YW7A 5CLSA 3TB5A 2B3KA 2GU5A 2Q94A 4FUKA 2B3HA 4IKTA 4IKSA 4FO8A 3L24A 1WKMA 3BIQA 3PKEA 3FMQA 1QXYA 2BHBA 4U6EA 3PKCA 1C21A 4ZWOA 1XGSA 4FLLA 2GZ5A 2V3ZA 3MX6A 4U75A 4U71A 4B28A 5CDVA 4ZWUA 1O0XA 3PKAA 2GU7A 2Q8KA 4FLIA 1M35A 1BN5A 4IU6A 2GG9A 1XNZA 2P99A 1KP0A 2EVOA 2BHDA 4RGZ1 2EA4A 2P98A 2GG8A 5CDLA 4A6WA 1BOAA 4FKCA 2GTXA 1KQ0A 3IU7A 4S01A 2GG7A 2V3YA 3L7GA 5FCFA 4S2RP 4KM3A 1WLRA 2OAZA 3MR1A 5D6FA 1C23A 5CDEA 2Q96A 1KQ9A 4RZYA 1R5HA 3CTZA 4PNCA 5E5BA 4U6JA 4U6WA 2DFIA 2G6PA 5JHUA 4JUQA 2GU4A 3RORA 1C27A 1W7VA 3PKBA 2BHCA 2BWUA 1WL6A 4R60A 1QZYA 2MATA 4A6VA 1Y1NA 4U6ZA 4RZZA 2Q92A 4U76A 4IDYA 2BWXA 2GA2A 1PV9A 2B3LA 1XGNA 5JI6A 1YW9A 3FM3A 3TAVA 5JFRA 4S2TP 1YW8A 4FLJA 4QR8A 1B59A 2BWYA 3PKDA 4FLKA 1QXZA 4ZNGA 2GGCA 1YJ3A 4U6CA
chains in the Genus database with same CATH superfamily
3CB5A 1C24A 4U73A 1R5GA 2BWVA 2BH3A 2BN7A 1WY2A 2BHAA 2BB7A 3Q6DA 1R58A 4IECA 3FMRA 4PV4A 3S6BA 2NQ6A 5CIKA 1WN1A 2Q93A 4IPAA 2V3XA 2ADUA 3CB6A 1W2MA 2P9AA 1C22A 4U70A 4IF7A 1CHMA 2GGBA 3IG4A 1A16A 3MATA 5D6EA 5FCHA 4IKUA 1XGOA 2IW2A 1XGMA 4U69A 3IU8A 1B6AA 2BWTA 4EGEA 1MATA 4OOKA 1QXWA 2BWSA 2HOWA 4FO7A 5CNXA 4Z7MA 1YVMA 2ZSGA 3IU9A 3BIPA 1N51A 4HXXA 2GG5A 2GG0A 2Q95A 4S00A 1JAWA 4MATA 1WL9A 3BITA 4ZWPA 4U1BA 2GG2A 2EA2A 5CE6A 2NQ7A 2GG3A 3D27A 4IKRA 3RVAA 2EVCA 2OKNA 1WBQA 2BWWA 2GU6A 2EVMA 2V6CA 1YW7A 5CLSA 3TB5A 2B3KA 2GU5A 2Q94A 4FUKA 2B3HA 4IKTA 4IKSA 4FO8A 3L24A 1WKMA 3BIQA 3PKEA 3FMQA 1QXYA 2BHBA 4U6EA 3PKCA 1C21A 4ZWOA 1XGSA 4FLLA 2GZ5A 2V3ZA 3MX6A 4U75A 4U71A 4B28A 5CDVA 4ZWUA 1O0XA 3PKAA 2GU7A 2Q8KA 4FLIA 1M35A 1BN5A 4IU6A 2GG9A 1XNZA 2P99A 1KP0A 2EVOA 2BHDA 4RGZ1 2EA4A 2P98A 2GG8A 5CDLA 4A6WA 1BOAA 4FKCA 2GTXA 1KQ0A 3IU7A 4S01A 2GG7A 2V3YA 3L7GA 5FCFA 4S2RP 4KM3A 1WLRA 2OAZA 3MR1A 5D6FA 1C23A 5CDEA 2Q96A 1KQ9A 4RZYA 1R5HA 3CTZA 4PNCA 5E5BA 4U6JA 4U6WA 2DFIA 2G6PA 5JHUA 4JUQA 2GU4A 3RORA 1C27A 1W7VA 3PKBA 2BHCA 2BWUA 1WL6A 4R60A 1QZYA 2MATA 4A6VA 1Y1NA 4U6ZA 4RZZA 2Q92A 4U76A 4IDYA 2BWXA 2GA2A 1PV9A 2B3LA 1XGNA 5JI6A 1YW9A 3FM3A 3TAVA 5JFRA 4S2TP 1YW8A 4FLJA 4QR8A 1B59A 2BWYA 3PKDA 4FLKA 1QXZA 4ZNGA 2GGCA 1YJ3A 4U6CA
chains in the Genus database with same CATH topology
3CB5A 1C24A 4U73A 1R5GA 2BWVA 2BH3A 2BN7A 1WY2A 2BHAA 2BB7A 3Q6DA 1R58A 4IECA 3FMRA 4PV4A 3S6BA 2NQ6A 5CIKA 1WN1A 2Q93A 4IPAA 2V3XA 2ADUA 3CB6A 1W2MA 2P9AA 1C22A 4U70A 4IF7A 1CHMA 2GGBA 3IG4A 1A16A 3MATA 5D6EA 5FCHA 4IKUA 1XGOA 2IW2A 1XGMA 4U69A 3IU8A 1B6AA 2BWTA 4EGEA 1MATA 4OOKA 1QXWA 2BWSA 2HOWA 4FO7A 5CNXA 4Z7MA 1YVMA 2ZSGA 3IU9A 3BIPA 1N51A 4HXXA 2GG5A 2GG0A 2Q95A 4S00A 1JAWA 4MATA 1WL9A 3BITA 4ZWPA 4U1BA 2GG2A 2EA2A 5CE6A 2NQ7A 2GG3A 3D27A 4IKRA 3RVAA 2EVCA 2OKNA 1WBQA 2BWWA 2GU6A 2EVMA 2V6CA 1YW7A 5CLSA 3TB5A 2B3KA 2GU5A 2Q94A 4FUKA 2B3HA 4IKTA 4IKSA 4FO8A 3L24A 1WKMA 3BIQA 3PKEA 3FMQA 1QXYA 2BHBA 4U6EA 3PKCA 1C21A 4ZWOA 1XGSA 4FLLA 2GZ5A 2V3ZA 3MX6A 4U75A 4U71A 4B28A 5CDVA 4ZWUA 1O0XA 3PKAA 2GU7A 2Q8KA 4FLIA 1M35A 1BN5A 4IU6A 2GG9A 1XNZA 2P99A 1KP0A 2EVOA 2BHDA 4RGZ1 2EA4A 2P98A 2GG8A 5CDLA 4A6WA 1BOAA 4FKCA 2GTXA 1KQ0A 3IU7A 4S01A 2GG7A 2V3YA 3L7GA 5FCFA 4S2RP 4KM3A 1WLRA 2OAZA 3MR1A 5D6FA 1C23A 5CDEA 2Q96A 1KQ9A 4RZYA 1R5HA 3CTZA 4PNCA 5E5BA 4U6JA 4U6WA 2DFIA 2G6PA 5JHUA 4JUQA 2GU4A 3RORA 1C27A 1W7VA 3PKBA 2BHCA 2BWUA 1WL6A 4R60A 1QZYA 2MATA 4A6VA 1Y1NA 4U6ZA 4RZZA 2Q92A 4U76A 4IDYA 2BWXA 2GA2A 1PV9A 2B3LA 1XGNA 5JI6A 1YW9A 3FM3A 3TAVA 5JFRA 4S2TP 1YW8A 4FLJA 4QR8A 1B59A 2BWYA 3PKDA 4FLKA 1QXZA 4ZNGA 2GGCA 1YJ3A 4U6CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CB5 A;  1C24 A;  4U73 A;  1R5G A;  2BWV A;  2BH3 A;  2BN7 A;  1WY2 A;  2BHA A;  2BB7 A;  3Q6D A;  1R58 A;  4IEC A;  3FMR A;  4PV4 A;  3S6B A;  2NQ6 A;  5CIK A;  1WN1 A;  2Q93 A;  4IPA A;  2V3X A;  2ADU A;  3CB6 A;  1W2M A;  2P9A A;  1C22 A;  4U70 A;  4IF7 A;  1CHM A;  2GGB A;  3IG4 A;  1A16 A;  3MAT A;  5D6E A;  5FCH A;  4IKU A;  1XGO A;  2IW2 A;  1XGM A;  4U69 A;  3IU8 A;  1B6A A;  2BWT A;  4EGE A;  1MAT A;  4OOK A;  1QXW A;  2BWS A;  2HOW A;  4FO7 A;  5CNX A;  4Z7M A;  1YVM A;  2ZSG A;  3IU9 A;  3BIP A;  1N51 A;  4HXX A;  2GG5 A;  2GG0 A;  2Q95 A;  4S00 A;  1JAW A;  4MAT A;  1WL9 A;  3BIT A;  4ZWP A;  4U1B A;  2GG2 A;  2EA2 A;  5CE6 A;  2NQ7 A;  2GG3 A;  3D27 A;  4IKR A;  3RVA A;  2EVC A;  2OKN A;  1WBQ A;  2BWW A;  2GU6 A;  2EVM A;  2V6C A;  1YW7 A;  5CLS A;  3TB5 A;  2B3K A;  2GU5 A;  2Q94 A;  4FUK A;  2B3H A;  4IKT A;  4IKS A;  4FO8 A;  3L24 A;  1WKM A;  3BIQ A;  3PKE A;  3FMQ A;  1QXY A;  2BHB A;  4U6E A;  3PKC A;  1C21 A;  4ZWO A;  1XGS A;  4FLL A;  2GZ5 A;  2V3Z A;  3MX6 A;  4U75 A;  4U71 A;  4B28 A;  5CDV A;  4ZWU A;  1O0X A;  3PKA A;  2GU7 A;  2Q8K A;  4FLI A;  1M35 A;  1BN5 A;  4IU6 A;  2GG9 A;  1XNZ A;  2P99 A;  1KP0 A;  2EVO A;  2BHD A;  4RGZ 1;  2EA4 A;  2P98 A;  2GG8 A;  5CDL A;  4A6W A;  1BOA A;  4FKC A;  2GTX A;  1KQ0 A;  3IU7 A;  4S01 A;  2GG7 A;  2V3Y A;  3L7G A;  5FCF A;  4S2R P;  4KM3 A;  1WLR A;  2OAZ A;  3MR1 A;  5D6F A;  1C23 A;  5CDE A;  2Q96 A;  1KQ9 A;  4RZY A;  1R5H A;  3CTZ A;  4PNC A;  5E5B A;  4U6J A;  4U6W A;  2DFI A;  2G6P A;  5JHU A;  4JUQ A;  2GU4 A;  3ROR A;  1C27 A;  1W7V A;  3PKB A;  2BHC A;  2BWU A;  1WL6 A;  4R60 A;  1QZY A;  2MAT A;  4A6V A;  1Y1N A;  4U6Z A;  4RZZ A;  2Q92 A;  4U76 A;  4IDY A;  2BWX A;  2GA2 A;  1PV9 A;  2B3L A;  1XGN A;  5JI6 A;  1YW9 A;  3FM3 A;  3TAV A;  5JFR A;  4S2T P;  1YW8 A;  4FLJ A;  4QR8 A;  1B59 A;  2BWY A;  3PKD A;  4FLK A;  1QXZ A;  4ZNG A;  2GGC A;  1YJ3 A;  4U6C A; 
#chains in the Genus database with same CATH topology
 3CB5 A;  1C24 A;  4U73 A;  1R5G A;  2BWV A;  2BH3 A;  2BN7 A;  1WY2 A;  2BHA A;  2BB7 A;  3Q6D A;  1R58 A;  4IEC A;  3FMR A;  4PV4 A;  3S6B A;  2NQ6 A;  5CIK A;  1WN1 A;  2Q93 A;  4IPA A;  2V3X A;  2ADU A;  3CB6 A;  1W2M A;  2P9A A;  1C22 A;  4U70 A;  4IF7 A;  1CHM A;  2GGB A;  3IG4 A;  1A16 A;  3MAT A;  5D6E A;  5FCH A;  4IKU A;  1XGO A;  2IW2 A;  1XGM A;  4U69 A;  3IU8 A;  1B6A A;  2BWT A;  4EGE A;  1MAT A;  4OOK A;  1QXW A;  2BWS A;  2HOW A;  4FO7 A;  5CNX A;  4Z7M A;  1YVM A;  2ZSG A;  3IU9 A;  3BIP A;  1N51 A;  4HXX A;  2GG5 A;  2GG0 A;  2Q95 A;  4S00 A;  1JAW A;  4MAT A;  1WL9 A;  3BIT A;  4ZWP A;  4U1B A;  2GG2 A;  2EA2 A;  5CE6 A;  2NQ7 A;  2GG3 A;  3D27 A;  4IKR A;  3RVA A;  2EVC A;  2OKN A;  1WBQ A;  2BWW A;  2GU6 A;  2EVM A;  2V6C A;  1YW7 A;  5CLS A;  3TB5 A;  2B3K A;  2GU5 A;  2Q94 A;  4FUK A;  2B3H A;  4IKT A;  4IKS A;  4FO8 A;  3L24 A;  1WKM A;  3BIQ A;  3PKE A;  3FMQ A;  1QXY A;  2BHB A;  4U6E A;  3PKC A;  1C21 A;  4ZWO A;  1XGS A;  4FLL A;  2GZ5 A;  2V3Z A;  3MX6 A;  4U75 A;  4U71 A;  4B28 A;  5CDV A;  4ZWU A;  1O0X A;  3PKA A;  2GU7 A;  2Q8K A;  4FLI A;  1M35 A;  1BN5 A;  4IU6 A;  2GG9 A;  1XNZ A;  2P99 A;  1KP0 A;  2EVO A;  2BHD A;  4RGZ 1;  2EA4 A;  2P98 A;  2GG8 A;  5CDL A;  4A6W A;  1BOA A;  4FKC A;  2GTX A;  1KQ0 A;  3IU7 A;  4S01 A;  2GG7 A;  2V3Y A;  3L7G A;  5FCF A;  4S2R P;  4KM3 A;  1WLR A;  2OAZ A;  3MR1 A;  5D6F A;  1C23 A;  5CDE A;  2Q96 A;  1KQ9 A;  4RZY A;  1R5H A;  3CTZ A;  4PNC A;  5E5B A;  4U6J A;  4U6W A;  2DFI A;  2G6P A;  5JHU A;  4JUQ A;  2GU4 A;  3ROR A;  1C27 A;  1W7V A;  3PKB A;  2BHC A;  2BWU A;  1WL6 A;  4R60 A;  1QZY A;  2MAT A;  4A6V A;  1Y1N A;  4U6Z A;  4RZZ A;  2Q92 A;  4U76 A;  4IDY A;  2BWX A;  2GA2 A;  1PV9 A;  2B3L A;  1XGN A;  5JI6 A;  1YW9 A;  3FM3 A;  3TAV A;  5JFR A;  4S2T P;  1YW8 A;  4FLJ A;  4QR8 A;  1B59 A;  2BWY A;  3PKD A;  4FLK A;  1QXZ A;  4ZNG A;  2GGC A;  1YJ3 A;  4U6C A; 
#chains in the Genus database with same CATH homology
 3CB5 A;  1C24 A;  4U73 A;  1R5G A;  2BWV A;  2BH3 A;  2BN7 A;  1WY2 A;  2BHA A;  2BB7 A;  3Q6D A;  1R58 A;  4IEC A;  3FMR A;  4PV4 A;  3S6B A;  2NQ6 A;  5CIK A;  1WN1 A;  2Q93 A;  4IPA A;  2V3X A;  2ADU A;  3CB6 A;  1W2M A;  2P9A A;  1C22 A;  4U70 A;  4IF7 A;  1CHM A;  2GGB A;  3IG4 A;  1A16 A;  3MAT A;  5D6E A;  5FCH A;  4IKU A;  1XGO A;  2IW2 A;  1XGM A;  4U69 A;  3IU8 A;  1B6A A;  2BWT A;  4EGE A;  1MAT A;  4OOK A;  1QXW A;  2BWS A;  2HOW A;  4FO7 A;  5CNX A;  4Z7M A;  1YVM A;  2ZSG A;  3IU9 A;  3BIP A;  1N51 A;  4HXX A;  2GG5 A;  2GG0 A;  2Q95 A;  4S00 A;  1JAW A;  4MAT A;  1WL9 A;  3BIT A;  4ZWP A;  4U1B A;  2GG2 A;  2EA2 A;  5CE6 A;  2NQ7 A;  2GG3 A;  3D27 A;  4IKR A;  3RVA A;  2EVC A;  2OKN A;  1WBQ A;  2BWW A;  2GU6 A;  2EVM A;  2V6C A;  1YW7 A;  5CLS A;  3TB5 A;  2B3K A;  2GU5 A;  2Q94 A;  4FUK A;  2B3H A;  4IKT A;  4IKS A;  4FO8 A;  3L24 A;  1WKM A;  3BIQ A;  3PKE A;  3FMQ A;  1QXY A;  2BHB A;  4U6E A;  3PKC A;  1C21 A;  4ZWO A;  1XGS A;  4FLL A;  2GZ5 A;  2V3Z A;  3MX6 A;  4U75 A;  4U71 A;  4B28 A;  5CDV A;  4ZWU A;  1O0X A;  3PKA A;  2GU7 A;  2Q8K A;  4FLI A;  1M35 A;  1BN5 A;  4IU6 A;  2GG9 A;  1XNZ A;  2P99 A;  1KP0 A;  2EVO A;  2BHD A;  4RGZ 1;  2EA4 A;  2P98 A;  2GG8 A;  5CDL A;  4A6W A;  1BOA A;  4FKC A;  2GTX A;  1KQ0 A;  3IU7 A;  4S01 A;  2GG7 A;  2V3Y A;  3L7G A;  5FCF A;  4S2R P;  4KM3 A;  1WLR A;  2OAZ A;  3MR1 A;  5D6F A;  1C23 A;  5CDE A;  2Q96 A;  1KQ9 A;  4RZY A;  1R5H A;  3CTZ A;  4PNC A;  5E5B A;  4U6J A;  4U6W A;  2DFI A;  2G6P A;  5JHU A;  4JUQ A;  2GU4 A;  3ROR A;  1C27 A;  1W7V A;  3PKB A;  2BHC A;  2BWU A;  1WL6 A;  4R60 A;  1QZY A;  2MAT A;  4A6V A;  1Y1N A;  4U6Z A;  4RZZ A;  2Q92 A;  4U76 A;  4IDY A;  2BWX A;  2GA2 A;  1PV9 A;  2B3L A;  1XGN A;  5JI6 A;  1YW9 A;  3FM3 A;  3TAV A;  5JFR A;  4S2T P;  1YW8 A;  4FLJ A;  4QR8 A;  1B59 A;  2BWY A;  3PKD A;  4FLK A;  1QXZ A;  4ZNG A;  2GGC A;  1YJ3 A;  4U6C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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