3TAVA

Crystal structure of a methionine aminopeptidase from mycobacterium abscessus
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
264
structure length
264
Chain Sequence
VGLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAGAVPSFLGYHGFPASICSSVNDQVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFAVGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGYGGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDGSRAAHWEHTVAVTEAGPRILTMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
source organism Mycobacterium abscessus
total genus 82
structure length 264
sequence length 264
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tavA00
2V3YA 1YW8A 2GGBA 2V6CA 4ZWUA 1R5HA 2GU6A 4RZYA 2Q92A 1QZYA 3BITA 3D27A 2GU4A 2BWSA 1WL9A 1WY2A 5CDVA 3IU8A 2GTXA 1R58A 3IG4A 1A16A 2IW2A 1B59A 3TB5A 4KM3A 4JUQA 2OAZA 5JHUA 2BWWA 2GA2A 2HOWA 2BH3A 2Q8KA 3BIQA 2P9AA 4S2TP 2G6PA 4U76A 5CE6A 5FCHA 1WL6A 2GG3A 4U6EA 1QXYA 3CB6A 1N51A 3MR1A 1KQ0A 4IKTA 4FO7A 4FO8A 5JI6A 1Y1NA 1W2MA 4S01A 2B3KA 4FUKA 2NQ6A 2GG7A 2BB7A 4QR8A 2B3LA 2MATA 1CHMA 4EGEA 4IU6A 2Q95A 1XGNA 3L7GA 5FCFA 2BWXA 2Q94A 1YVMA 2GG0A 3TAVA 4RZZA 4IF7A 3L24A 4FLJA 2GG2A 1PV9A 3PKBA 4RGZ1 4U69A 1KP0A 2GU7A 2GZ5A 5JFRA 2BWUA 1XGSA 2B3HA 2BHAA 1C22A 1XGOA 4HXXA 1KQ9A 2P98A 3S6BA 1WBQA 4IKUA 3CB5A 4S2RP 2BWVA 3PKDA 2GG8A 3PKAA 1WKMA 4ZWPA 1WLRA 4IDYA 3RVAA 2BHBA 2EA2A 5CDLA 4PNCA 3FM3A 4OOKA 1XGMA 2GG9A 2ZSGA 4A6WA 4IECA 1R5GA 2EVCA 3FMRA 1M35A 2BHCA 1W7VA 2BWYA 5D6EA 2BHDA 4FKCA 4PV4A 3PKCA 5CLSA 1C24A 4ZWOA 2BWTA 2ADUA 4U6WA 2P99A 2GU5A 1QXWA 2DFIA 2EA4A 1C27A 1BN5A 3RORA 4S00A 3CTZA 1YW9A 1B6AA 4U6ZA 2GG5A 3FMQA 4Z7MA 5D6FA 3MX6A 1WN1A 3BIPA 4U70A 1YJ3A 2Q93A 4IKRA 4U71A 2V3ZA 4IPAA 2NQ7A 1YW7A 2EVMA 4U6CA 5CDEA 1O0XA 1QXZA 4A6VA 3Q6DA 4FLLA 4MATA 4ZNGA 3IU9A 1C23A 1MATA 2GGCA 4B28A 5CIKA 3MATA 1C21A 2Q96A 1BOAA 4U73A 1JAWA 3PKEA 4FLKA 2EVOA 1XNZA 5CNXA 5E5BA 4IKSA 4U6JA 2OKNA 4FLIA 4U1BA 4U75A 3IU7A 2BN7A 2V3XA 4R60A
chains in the Genus database with same CATH superfamily
2V3YA 1YW8A 2GGBA 2V6CA 4ZWUA 1R5HA 2GU6A 4RZYA 2Q92A 1QZYA 3BITA 3D27A 2GU4A 2BWSA 1WL9A 1WY2A 5CDVA 3IU8A 2GTXA 1R58A 3IG4A 1A16A 2IW2A 1B59A 3TB5A 4KM3A 4JUQA 2OAZA 5JHUA 2BWWA 2GA2A 2HOWA 2BH3A 2Q8KA 3BIQA 2P9AA 4S2TP 2G6PA 4U76A 5CE6A 5FCHA 1WL6A 2GG3A 4U6EA 1QXYA 3CB6A 1N51A 3MR1A 1KQ0A 4IKTA 4FO7A 4FO8A 5JI6A 1Y1NA 1W2MA 4S01A 2B3KA 4FUKA 2NQ6A 2GG7A 2BB7A 4QR8A 2B3LA 2MATA 1CHMA 4EGEA 4IU6A 2Q95A 1XGNA 3L7GA 5FCFA 2BWXA 2Q94A 1YVMA 2GG0A 3TAVA 4RZZA 4IF7A 3L24A 4FLJA 2GG2A 1PV9A 3PKBA 4RGZ1 4U69A 1KP0A 2GU7A 2GZ5A 5JFRA 2BWUA 1XGSA 2B3HA 2BHAA 1C22A 1XGOA 4HXXA 1KQ9A 2P98A 3S6BA 1WBQA 4IKUA 3CB5A 4S2RP 2BWVA 3PKDA 2GG8A 3PKAA 1WKMA 4ZWPA 1WLRA 4IDYA 3RVAA 2BHBA 2EA2A 5CDLA 4PNCA 3FM3A 4OOKA 1XGMA 2GG9A 2ZSGA 4A6WA 4IECA 1R5GA 2EVCA 3FMRA 1M35A 2BHCA 1W7VA 2BWYA 5D6EA 2BHDA 4FKCA 4PV4A 3PKCA 5CLSA 1C24A 4ZWOA 2BWTA 2ADUA 4U6WA 2P99A 2GU5A 1QXWA 2DFIA 2EA4A 1C27A 1BN5A 3RORA 4S00A 3CTZA 1YW9A 1B6AA 4U6ZA 2GG5A 3FMQA 4Z7MA 5D6FA 3MX6A 1WN1A 3BIPA 4U70A 1YJ3A 2Q93A 4IKRA 4U71A 2V3ZA 4IPAA 2NQ7A 1YW7A 2EVMA 4U6CA 5CDEA 1O0XA 1QXZA 4A6VA 3Q6DA 4FLLA 4MATA 4ZNGA 3IU9A 1C23A 1MATA 2GGCA 4B28A 5CIKA 3MATA 1C21A 2Q96A 1BOAA 4U73A 1JAWA 3PKEA 4FLKA 2EVOA 1XNZA 5CNXA 5E5BA 4IKSA 4U6JA 2OKNA 4FLIA 4U1BA 4U75A 3IU7A 2BN7A 2V3XA 4R60A
chains in the Genus database with same CATH topology
2V3YA 1YW8A 2GGBA 2V6CA 4ZWUA 1R5HA 2GU6A 4RZYA 2Q92A 1QZYA 3BITA 3D27A 2GU4A 2BWSA 1WL9A 1WY2A 5CDVA 3IU8A 2GTXA 1R58A 3IG4A 1A16A 2IW2A 1B59A 3TB5A 4KM3A 4JUQA 2OAZA 5JHUA 2BWWA 2GA2A 2HOWA 2BH3A 2Q8KA 3BIQA 2P9AA 4S2TP 2G6PA 4U76A 5CE6A 5FCHA 1WL6A 2GG3A 4U6EA 1QXYA 3CB6A 1N51A 3MR1A 1KQ0A 4IKTA 4FO7A 4FO8A 5JI6A 1Y1NA 1W2MA 4S01A 2B3KA 4FUKA 2NQ6A 2GG7A 2BB7A 4QR8A 2B3LA 2MATA 1CHMA 4EGEA 4IU6A 2Q95A 1XGNA 3L7GA 5FCFA 2BWXA 2Q94A 1YVMA 2GG0A 3TAVA 4RZZA 4IF7A 3L24A 4FLJA 2GG2A 1PV9A 3PKBA 4RGZ1 4U69A 1KP0A 2GU7A 2GZ5A 5JFRA 2BWUA 1XGSA 2B3HA 2BHAA 1C22A 1XGOA 4HXXA 1KQ9A 2P98A 3S6BA 1WBQA 4IKUA 3CB5A 4S2RP 2BWVA 3PKDA 2GG8A 3PKAA 1WKMA 4ZWPA 1WLRA 4IDYA 3RVAA 2BHBA 2EA2A 5CDLA 4PNCA 3FM3A 4OOKA 1XGMA 2GG9A 2ZSGA 4A6WA 4IECA 1R5GA 2EVCA 3FMRA 1M35A 2BHCA 1W7VA 2BWYA 5D6EA 2BHDA 4FKCA 4PV4A 3PKCA 5CLSA 1C24A 4ZWOA 2BWTA 2ADUA 4U6WA 2P99A 2GU5A 1QXWA 2DFIA 2EA4A 1C27A 1BN5A 3RORA 4S00A 3CTZA 1YW9A 1B6AA 4U6ZA 2GG5A 3FMQA 4Z7MA 5D6FA 3MX6A 1WN1A 3BIPA 4U70A 1YJ3A 2Q93A 4IKRA 4U71A 2V3ZA 4IPAA 2NQ7A 1YW7A 2EVMA 4U6CA 5CDEA 1O0XA 1QXZA 4A6VA 3Q6DA 4FLLA 4MATA 4ZNGA 3IU9A 1C23A 1MATA 2GGCA 4B28A 5CIKA 3MATA 1C21A 2Q96A 1BOAA 4U73A 1JAWA 3PKEA 4FLKA 2EVOA 1XNZA 5CNXA 5E5BA 4IKSA 4U6JA 2OKNA 4FLIA 4U1BA 4U75A 3IU7A 2BN7A 2V3XA 4R60A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2V3Y A;  1YW8 A;  2GGB A;  2V6C A;  4ZWU A;  1R5H A;  2GU6 A;  4RZY A;  2Q92 A;  1QZY A;  3BIT A;  3D27 A;  2GU4 A;  2BWS A;  1WL9 A;  1WY2 A;  5CDV A;  3IU8 A;  2GTX A;  1R58 A;  3IG4 A;  1A16 A;  2IW2 A;  1B59 A;  3TB5 A;  4KM3 A;  4JUQ A;  2OAZ A;  5JHU A;  2BWW A;  2GA2 A;  2HOW A;  2BH3 A;  2Q8K A;  3BIQ A;  2P9A A;  4S2T P;  2G6P A;  4U76 A;  5CE6 A;  5FCH A;  1WL6 A;  2GG3 A;  4U6E A;  1QXY A;  3CB6 A;  1N51 A;  3MR1 A;  1KQ0 A;  4IKT A;  4FO7 A;  4FO8 A;  5JI6 A;  1Y1N A;  1W2M A;  4S01 A;  2B3K A;  4FUK A;  2NQ6 A;  2GG7 A;  2BB7 A;  4QR8 A;  2B3L A;  2MAT A;  1CHM A;  4EGE A;  4IU6 A;  2Q95 A;  1XGN A;  3L7G A;  5FCF A;  2BWX A;  2Q94 A;  1YVM A;  2GG0 A;  3TAV A;  4RZZ A;  4IF7 A;  3L24 A;  4FLJ A;  2GG2 A;  1PV9 A;  3PKB A;  4RGZ 1;  4U69 A;  1KP0 A;  2GU7 A;  2GZ5 A;  5JFR A;  2BWU A;  1XGS A;  2B3H A;  2BHA A;  1C22 A;  1XGO A;  4HXX A;  1KQ9 A;  2P98 A;  3S6B A;  1WBQ A;  4IKU A;  3CB5 A;  4S2R P;  2BWV A;  3PKD A;  2GG8 A;  3PKA A;  1WKM A;  4ZWP A;  1WLR A;  4IDY A;  3RVA A;  2BHB A;  2EA2 A;  5CDL A;  4PNC A;  3FM3 A;  4OOK A;  1XGM A;  2GG9 A;  2ZSG A;  4A6W A;  4IEC A;  1R5G A;  2EVC A;  3FMR A;  1M35 A;  2BHC A;  1W7V A;  2BWY A;  5D6E A;  2BHD A;  4FKC A;  4PV4 A;  3PKC A;  5CLS A;  1C24 A;  4ZWO A;  2BWT A;  2ADU A;  4U6W A;  2P99 A;  2GU5 A;  1QXW A;  2DFI A;  2EA4 A;  1C27 A;  1BN5 A;  3ROR A;  4S00 A;  3CTZ A;  1YW9 A;  1B6A A;  4U6Z A;  2GG5 A;  3FMQ A;  4Z7M A;  5D6F A;  3MX6 A;  1WN1 A;  3BIP A;  4U70 A;  1YJ3 A;  2Q93 A;  4IKR A;  4U71 A;  2V3Z A;  4IPA A;  2NQ7 A;  1YW7 A;  2EVM A;  4U6C A;  5CDE A;  1O0X A;  1QXZ A;  4A6V A;  3Q6D A;  4FLL A;  4MAT A;  4ZNG A;  3IU9 A;  1C23 A;  1MAT A;  2GGC A;  4B28 A;  5CIK A;  3MAT A;  1C21 A;  2Q96 A;  1BOA A;  4U73 A;  1JAW A;  3PKE A;  4FLK A;  2EVO A;  1XNZ A;  5CNX A;  5E5B A;  4IKS A;  4U6J A;  2OKN A;  4FLI A;  4U1B A;  4U75 A;  3IU7 A;  2BN7 A;  2V3X A;  4R60 A; 
#chains in the Genus database with same CATH topology
 2V3Y A;  1YW8 A;  2GGB A;  2V6C A;  4ZWU A;  1R5H A;  2GU6 A;  4RZY A;  2Q92 A;  1QZY A;  3BIT A;  3D27 A;  2GU4 A;  2BWS A;  1WL9 A;  1WY2 A;  5CDV A;  3IU8 A;  2GTX A;  1R58 A;  3IG4 A;  1A16 A;  2IW2 A;  1B59 A;  3TB5 A;  4KM3 A;  4JUQ A;  2OAZ A;  5JHU A;  2BWW A;  2GA2 A;  2HOW A;  2BH3 A;  2Q8K A;  3BIQ A;  2P9A A;  4S2T P;  2G6P A;  4U76 A;  5CE6 A;  5FCH A;  1WL6 A;  2GG3 A;  4U6E A;  1QXY A;  3CB6 A;  1N51 A;  3MR1 A;  1KQ0 A;  4IKT A;  4FO7 A;  4FO8 A;  5JI6 A;  1Y1N A;  1W2M A;  4S01 A;  2B3K A;  4FUK A;  2NQ6 A;  2GG7 A;  2BB7 A;  4QR8 A;  2B3L A;  2MAT A;  1CHM A;  4EGE A;  4IU6 A;  2Q95 A;  1XGN A;  3L7G A;  5FCF A;  2BWX A;  2Q94 A;  1YVM A;  2GG0 A;  3TAV A;  4RZZ A;  4IF7 A;  3L24 A;  4FLJ A;  2GG2 A;  1PV9 A;  3PKB A;  4RGZ 1;  4U69 A;  1KP0 A;  2GU7 A;  2GZ5 A;  5JFR A;  2BWU A;  1XGS A;  2B3H A;  2BHA A;  1C22 A;  1XGO A;  4HXX A;  1KQ9 A;  2P98 A;  3S6B A;  1WBQ A;  4IKU A;  3CB5 A;  4S2R P;  2BWV A;  3PKD A;  2GG8 A;  3PKA A;  1WKM A;  4ZWP A;  1WLR A;  4IDY A;  3RVA A;  2BHB A;  2EA2 A;  5CDL A;  4PNC A;  3FM3 A;  4OOK A;  1XGM A;  2GG9 A;  2ZSG A;  4A6W A;  4IEC A;  1R5G A;  2EVC A;  3FMR A;  1M35 A;  2BHC A;  1W7V A;  2BWY A;  5D6E A;  2BHD A;  4FKC A;  4PV4 A;  3PKC A;  5CLS A;  1C24 A;  4ZWO A;  2BWT A;  2ADU A;  4U6W A;  2P99 A;  2GU5 A;  1QXW A;  2DFI A;  2EA4 A;  1C27 A;  1BN5 A;  3ROR A;  4S00 A;  3CTZ A;  1YW9 A;  1B6A A;  4U6Z A;  2GG5 A;  3FMQ A;  4Z7M A;  5D6F A;  3MX6 A;  1WN1 A;  3BIP A;  4U70 A;  1YJ3 A;  2Q93 A;  4IKR A;  4U71 A;  2V3Z A;  4IPA A;  2NQ7 A;  1YW7 A;  2EVM A;  4U6C A;  5CDE A;  1O0X A;  1QXZ A;  4A6V A;  3Q6D A;  4FLL A;  4MAT A;  4ZNG A;  3IU9 A;  1C23 A;  1MAT A;  2GGC A;  4B28 A;  5CIK A;  3MAT A;  1C21 A;  2Q96 A;  1BOA A;  4U73 A;  1JAW A;  3PKE A;  4FLK A;  2EVO A;  1XNZ A;  5CNX A;  5E5B A;  4IKS A;  4U6J A;  2OKN A;  4FLI A;  4U1B A;  4U75 A;  3IU7 A;  2BN7 A;  2V3X A;  4R60 A; 
#chains in the Genus database with same CATH homology
 2V3Y A;  1YW8 A;  2GGB A;  2V6C A;  4ZWU A;  1R5H A;  2GU6 A;  4RZY A;  2Q92 A;  1QZY A;  3BIT A;  3D27 A;  2GU4 A;  2BWS A;  1WL9 A;  1WY2 A;  5CDV A;  3IU8 A;  2GTX A;  1R58 A;  3IG4 A;  1A16 A;  2IW2 A;  1B59 A;  3TB5 A;  4KM3 A;  4JUQ A;  2OAZ A;  5JHU A;  2BWW A;  2GA2 A;  2HOW A;  2BH3 A;  2Q8K A;  3BIQ A;  2P9A A;  4S2T P;  2G6P A;  4U76 A;  5CE6 A;  5FCH A;  1WL6 A;  2GG3 A;  4U6E A;  1QXY A;  3CB6 A;  1N51 A;  3MR1 A;  1KQ0 A;  4IKT A;  4FO7 A;  4FO8 A;  5JI6 A;  1Y1N A;  1W2M A;  4S01 A;  2B3K A;  4FUK A;  2NQ6 A;  2GG7 A;  2BB7 A;  4QR8 A;  2B3L A;  2MAT A;  1CHM A;  4EGE A;  4IU6 A;  2Q95 A;  1XGN A;  3L7G A;  5FCF A;  2BWX A;  2Q94 A;  1YVM A;  2GG0 A;  3TAV A;  4RZZ A;  4IF7 A;  3L24 A;  4FLJ A;  2GG2 A;  1PV9 A;  3PKB A;  4RGZ 1;  4U69 A;  1KP0 A;  2GU7 A;  2GZ5 A;  5JFR A;  2BWU A;  1XGS A;  2B3H A;  2BHA A;  1C22 A;  1XGO A;  4HXX A;  1KQ9 A;  2P98 A;  3S6B A;  1WBQ A;  4IKU A;  3CB5 A;  4S2R P;  2BWV A;  3PKD A;  2GG8 A;  3PKA A;  1WKM A;  4ZWP A;  1WLR A;  4IDY A;  3RVA A;  2BHB A;  2EA2 A;  5CDL A;  4PNC A;  3FM3 A;  4OOK A;  1XGM A;  2GG9 A;  2ZSG A;  4A6W A;  4IEC A;  1R5G A;  2EVC A;  3FMR A;  1M35 A;  2BHC A;  1W7V A;  2BWY A;  5D6E A;  2BHD A;  4FKC A;  4PV4 A;  3PKC A;  5CLS A;  1C24 A;  4ZWO A;  2BWT A;  2ADU A;  4U6W A;  2P99 A;  2GU5 A;  1QXW A;  2DFI A;  2EA4 A;  1C27 A;  1BN5 A;  3ROR A;  4S00 A;  3CTZ A;  1YW9 A;  1B6A A;  4U6Z A;  2GG5 A;  3FMQ A;  4Z7M A;  5D6F A;  3MX6 A;  1WN1 A;  3BIP A;  4U70 A;  1YJ3 A;  2Q93 A;  4IKR A;  4U71 A;  2V3Z A;  4IPA A;  2NQ7 A;  1YW7 A;  2EVM A;  4U6C A;  5CDE A;  1O0X A;  1QXZ A;  4A6V A;  3Q6D A;  4FLL A;  4MAT A;  4ZNG A;  3IU9 A;  1C23 A;  1MAT A;  2GGC A;  4B28 A;  5CIK A;  3MAT A;  1C21 A;  2Q96 A;  1BOA A;  4U73 A;  1JAW A;  3PKE A;  4FLK A;  2EVO A;  1XNZ A;  5CNX A;  5E5B A;  4IKS A;  4U6J A;  2OKN A;  4FLI A;  4U1B A;  4U75 A;  3IU7 A;  2BN7 A;  2V3X A;  4R60 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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