4FO8A

Pseudomonas aeruginosa metap with met, in mn form
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
259
structure length
259
Chain Sequence
TVTIKTPDDIEKMRIAGRLAAEVLEMIGEHIKPGVTTEELDRICHDYIVNEQKAIPAPLNYKGFPKSICTSINHVVCHGIPNEKPLKEGDILNVDITVIKDGYHGDTSKMFLVGKTPEWADRLCQITQECMYKGISVVRPGAHLGDIGEIIQKHAEKNGFSVVREYCGHGIGKVFHEEPQVLHYGRAGTGIELKEGMIFTIEPMINQGRPETRLLGDGWTAITKDRKLSAQWEHTVLVTADGYEILTLRNDETFPRTSA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Methionine excision captured by the structures of a methionine aminopeptidase
rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords Methionine aminopeptidase
total genus 83
structure length 259
sequence length 259
chains with identical sequence B, C, D
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2012-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4fo8A00
4FUKA 2BH3A 4U73A 2V3XA 2NQ7A 3TAVA 3IU8A 2GG0A 2V3ZA 3IU7A 1MATA 4IU6A 4RZZA 2BHAA 1XNZA 1YVMA 3FM3A 2BWVA 3L7GA 4U6EA 2BWTA 2GG8A 3L24A 5E5BA 1WL6A 3MX6A 1C24A 1C21A 1R58A 1W7VA 4FLLA 1WKMA 4U70A 1BN5A 1C27A 2GG7A 4Z7MA 2OKNA 3BIPA 2BWWA 1WN1A 2EVCA 4ZWPA 2BWSA 2BHBA 3D27A 2Q96A 2MATA 2NQ6A 3IG4A 4IF7A 1XGNA 3MATA 1BOAA 1C22A 2GA2A 4U75A 4FO7A 2BHCA 4FKCA 4U69A 1WL9A 1YW8A 1QXWA 4IECA 4U76A 4IKUA 1WY2A 2GU4A 2HOWA 1WLRA 3IU9A 2B3LA 2V6CA 4S01A 3RORA 4KM3A 4U71A 4A6VA 3CB5A 1YJ3A 1XGMA 4R60A 2BN7A 2P9AA 4JUQA 2EVMA 1PV9A 4FO8A 4EGEA 5CE6A 4IKSA 2B3KA 5FCHA 5JFRA 2G6PA 1KQ9A 1B6AA 1XGSA 2V3YA 3FMQA 2Q95A 1C23A 1W2MA 5D6EA 5FCFA 3PKDA 4S2TP 2BWYA 5JHUA 5CDEA 2BHDA 4U6WA 4ZWOA 4IDYA 1YW7A 1QXZA 2GG5A 4U6CA 1Y1NA 1O0XA 2Q92A 3RVAA 4ZWUA 2GGBA 4IPAA 4ZNGA 1B59A 3FMRA 4FLKA 3PKAA 4B28A 1WBQA 2Q94A 4S2RP 2BWXA 5CDVA 2ADUA 3PKBA 4RGZ1 4U1BA 1A16A 4QR8A 2GU5A 4U6ZA 3TB5A 1N51A 2BWUA 2ZSGA 2P99A 4MATA 3MR1A 2DFIA 1KP0A 3BIQA 4OOKA 1QXYA 1KQ0A 4FLIA 2GTXA 2Q8KA 4RZYA 3CB6A 2GG9A 2GU6A 3PKEA 2BB7A 3Q6DA 5CIKA 3S6BA 4U6JA 5JI6A 2P98A 5CDLA 2EA2A 2GG3A 3CTZA 4HXXA 4S00A 2GU7A 2OAZA 5CLSA 1QZYA 1JAWA 3PKCA 5D6FA 2EA4A 1CHMA 4A6WA 4FLJA 3BITA 4IKTA 1YW9A 1M35A 2EVOA 1R5GA 4IKRA 1XGOA 5CNXA 2GZ5A 4PNCA 2B3HA 2Q93A 2GG2A 4PV4A 2GGCA 2IW2A 1R5HA
chains in the Genus database with same CATH superfamily
4FUKA 2BH3A 4U73A 2V3XA 2NQ7A 3TAVA 3IU8A 2GG0A 2V3ZA 3IU7A 1MATA 4IU6A 4RZZA 2BHAA 1XNZA 1YVMA 3FM3A 2BWVA 3L7GA 4U6EA 2BWTA 2GG8A 3L24A 5E5BA 1WL6A 3MX6A 1C24A 1C21A 1R58A 1W7VA 4FLLA 1WKMA 4U70A 1BN5A 1C27A 2GG7A 4Z7MA 2OKNA 3BIPA 2BWWA 1WN1A 2EVCA 4ZWPA 2BWSA 2BHBA 3D27A 2Q96A 2MATA 2NQ6A 3IG4A 4IF7A 1XGNA 3MATA 1BOAA 1C22A 2GA2A 4U75A 4FO7A 2BHCA 4FKCA 4U69A 1WL9A 1YW8A 1QXWA 4IECA 4U76A 4IKUA 1WY2A 2GU4A 2HOWA 1WLRA 3IU9A 2B3LA 2V6CA 4S01A 3RORA 4KM3A 4U71A 4A6VA 3CB5A 1YJ3A 1XGMA 4R60A 2BN7A 2P9AA 4JUQA 2EVMA 1PV9A 4FO8A 4EGEA 5CE6A 4IKSA 2B3KA 5FCHA 5JFRA 2G6PA 1KQ9A 1B6AA 1XGSA 2V3YA 3FMQA 2Q95A 1C23A 1W2MA 5D6EA 5FCFA 3PKDA 4S2TP 2BWYA 5JHUA 5CDEA 2BHDA 4U6WA 4ZWOA 4IDYA 1YW7A 1QXZA 2GG5A 4U6CA 1Y1NA 1O0XA 2Q92A 3RVAA 4ZWUA 2GGBA 4IPAA 4ZNGA 1B59A 3FMRA 4FLKA 3PKAA 4B28A 1WBQA 2Q94A 4S2RP 2BWXA 5CDVA 2ADUA 3PKBA 4RGZ1 4U1BA 1A16A 4QR8A 2GU5A 4U6ZA 3TB5A 1N51A 2BWUA 2ZSGA 2P99A 4MATA 3MR1A 2DFIA 1KP0A 3BIQA 4OOKA 1QXYA 1KQ0A 4FLIA 2GTXA 2Q8KA 4RZYA 3CB6A 2GG9A 2GU6A 3PKEA 2BB7A 3Q6DA 5CIKA 3S6BA 4U6JA 5JI6A 2P98A 5CDLA 2EA2A 2GG3A 3CTZA 4HXXA 4S00A 2GU7A 2OAZA 5CLSA 1QZYA 1JAWA 3PKCA 5D6FA 2EA4A 1CHMA 4A6WA 4FLJA 3BITA 4IKTA 1YW9A 1M35A 2EVOA 1R5GA 4IKRA 1XGOA 5CNXA 2GZ5A 4PNCA 2B3HA 2Q93A 2GG2A 4PV4A 2GGCA 2IW2A 1R5HA
chains in the Genus database with same CATH topology
4FUKA 2BH3A 4U73A 2V3XA 2NQ7A 3TAVA 3IU8A 2GG0A 2V3ZA 3IU7A 1MATA 4IU6A 4RZZA 2BHAA 1XNZA 1YVMA 3FM3A 2BWVA 3L7GA 4U6EA 2BWTA 2GG8A 3L24A 5E5BA 1WL6A 3MX6A 1C24A 1C21A 1R58A 1W7VA 4FLLA 1WKMA 4U70A 1BN5A 1C27A 2GG7A 4Z7MA 2OKNA 3BIPA 2BWWA 1WN1A 2EVCA 4ZWPA 2BWSA 2BHBA 3D27A 2Q96A 2MATA 2NQ6A 3IG4A 4IF7A 1XGNA 3MATA 1BOAA 1C22A 2GA2A 4U75A 4FO7A 2BHCA 4FKCA 4U69A 1WL9A 1YW8A 1QXWA 4IECA 4U76A 4IKUA 1WY2A 2GU4A 2HOWA 1WLRA 3IU9A 2B3LA 2V6CA 4S01A 3RORA 4KM3A 4U71A 4A6VA 3CB5A 1YJ3A 1XGMA 4R60A 2BN7A 2P9AA 4JUQA 2EVMA 1PV9A 4FO8A 4EGEA 5CE6A 4IKSA 2B3KA 5FCHA 5JFRA 2G6PA 1KQ9A 1B6AA 1XGSA 2V3YA 3FMQA 2Q95A 1C23A 1W2MA 5D6EA 5FCFA 3PKDA 4S2TP 2BWYA 5JHUA 5CDEA 2BHDA 4U6WA 4ZWOA 4IDYA 1YW7A 1QXZA 2GG5A 4U6CA 1Y1NA 1O0XA 2Q92A 3RVAA 4ZWUA 2GGBA 4IPAA 4ZNGA 1B59A 3FMRA 4FLKA 3PKAA 4B28A 1WBQA 2Q94A 4S2RP 2BWXA 5CDVA 2ADUA 3PKBA 4RGZ1 4U1BA 1A16A 4QR8A 2GU5A 4U6ZA 3TB5A 1N51A 2BWUA 2ZSGA 2P99A 4MATA 3MR1A 2DFIA 1KP0A 3BIQA 4OOKA 1QXYA 1KQ0A 4FLIA 2GTXA 2Q8KA 4RZYA 3CB6A 2GG9A 2GU6A 3PKEA 2BB7A 3Q6DA 5CIKA 3S6BA 4U6JA 5JI6A 2P98A 5CDLA 2EA2A 2GG3A 3CTZA 4HXXA 4S00A 2GU7A 2OAZA 5CLSA 1QZYA 1JAWA 3PKCA 5D6FA 2EA4A 1CHMA 4A6WA 4FLJA 3BITA 4IKTA 1YW9A 1M35A 2EVOA 1R5GA 4IKRA 1XGOA 5CNXA 2GZ5A 4PNCA 2B3HA 2Q93A 2GG2A 4PV4A 2GGCA 2IW2A 1R5HA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4FUK A;  2BH3 A;  4U73 A;  2V3X A;  2NQ7 A;  3TAV A;  3IU8 A;  2GG0 A;  2V3Z A;  3IU7 A;  1MAT A;  4IU6 A;  4RZZ A;  2BHA A;  1XNZ A;  1YVM A;  3FM3 A;  2BWV A;  3L7G A;  4U6E A;  2BWT A;  2GG8 A;  3L24 A;  5E5B A;  1WL6 A;  3MX6 A;  1C24 A;  1C21 A;  1R58 A;  1W7V A;  4FLL A;  1WKM A;  4U70 A;  1BN5 A;  1C27 A;  2GG7 A;  4Z7M A;  2OKN A;  3BIP A;  2BWW A;  1WN1 A;  2EVC A;  4ZWP A;  2BWS A;  2BHB A;  3D27 A;  2Q96 A;  2MAT A;  2NQ6 A;  3IG4 A;  4IF7 A;  1XGN A;  3MAT A;  1BOA A;  1C22 A;  2GA2 A;  4U75 A;  4FO7 A;  2BHC A;  4FKC A;  4U69 A;  1WL9 A;  1YW8 A;  1QXW A;  4IEC A;  4U76 A;  4IKU A;  1WY2 A;  2GU4 A;  2HOW A;  1WLR A;  3IU9 A;  2B3L A;  2V6C A;  4S01 A;  3ROR A;  4KM3 A;  4U71 A;  4A6V A;  3CB5 A;  1YJ3 A;  1XGM A;  4R60 A;  2BN7 A;  2P9A A;  4JUQ A;  2EVM A;  1PV9 A;  4FO8 A;  4EGE A;  5CE6 A;  4IKS A;  2B3K A;  5FCH A;  5JFR A;  2G6P A;  1KQ9 A;  1B6A A;  1XGS A;  2V3Y A;  3FMQ A;  2Q95 A;  1C23 A;  1W2M A;  5D6E A;  5FCF A;  3PKD A;  4S2T P;  2BWY A;  5JHU A;  5CDE A;  2BHD A;  4U6W A;  4ZWO A;  4IDY A;  1YW7 A;  1QXZ A;  2GG5 A;  4U6C A;  1Y1N A;  1O0X A;  2Q92 A;  3RVA A;  4ZWU A;  2GGB A;  4IPA A;  4ZNG A;  1B59 A;  3FMR A;  4FLK A;  3PKA A;  4B28 A;  1WBQ A;  2Q94 A;  4S2R P;  2BWX A;  5CDV A;  2ADU A;  3PKB A;  4RGZ 1;  4U1B A;  1A16 A;  4QR8 A;  2GU5 A;  4U6Z A;  3TB5 A;  1N51 A;  2BWU A;  2ZSG A;  2P99 A;  4MAT A;  3MR1 A;  2DFI A;  1KP0 A;  3BIQ A;  4OOK A;  1QXY A;  1KQ0 A;  4FLI A;  2GTX A;  2Q8K A;  4RZY A;  3CB6 A;  2GG9 A;  2GU6 A;  3PKE A;  2BB7 A;  3Q6D A;  5CIK A;  3S6B A;  4U6J A;  5JI6 A;  2P98 A;  5CDL A;  2EA2 A;  2GG3 A;  3CTZ A;  4HXX A;  4S00 A;  2GU7 A;  2OAZ A;  5CLS A;  1QZY A;  1JAW A;  3PKC A;  5D6F A;  2EA4 A;  1CHM A;  4A6W A;  4FLJ A;  3BIT A;  4IKT A;  1YW9 A;  1M35 A;  2EVO A;  1R5G A;  4IKR A;  1XGO A;  5CNX A;  2GZ5 A;  4PNC A;  2B3H A;  2Q93 A;  2GG2 A;  4PV4 A;  2GGC A;  2IW2 A;  1R5H A; 
#chains in the Genus database with same CATH topology
 4FUK A;  2BH3 A;  4U73 A;  2V3X A;  2NQ7 A;  3TAV A;  3IU8 A;  2GG0 A;  2V3Z A;  3IU7 A;  1MAT A;  4IU6 A;  4RZZ A;  2BHA A;  1XNZ A;  1YVM A;  3FM3 A;  2BWV A;  3L7G A;  4U6E A;  2BWT A;  2GG8 A;  3L24 A;  5E5B A;  1WL6 A;  3MX6 A;  1C24 A;  1C21 A;  1R58 A;  1W7V A;  4FLL A;  1WKM A;  4U70 A;  1BN5 A;  1C27 A;  2GG7 A;  4Z7M A;  2OKN A;  3BIP A;  2BWW A;  1WN1 A;  2EVC A;  4ZWP A;  2BWS A;  2BHB A;  3D27 A;  2Q96 A;  2MAT A;  2NQ6 A;  3IG4 A;  4IF7 A;  1XGN A;  3MAT A;  1BOA A;  1C22 A;  2GA2 A;  4U75 A;  4FO7 A;  2BHC A;  4FKC A;  4U69 A;  1WL9 A;  1YW8 A;  1QXW A;  4IEC A;  4U76 A;  4IKU A;  1WY2 A;  2GU4 A;  2HOW A;  1WLR A;  3IU9 A;  2B3L A;  2V6C A;  4S01 A;  3ROR A;  4KM3 A;  4U71 A;  4A6V A;  3CB5 A;  1YJ3 A;  1XGM A;  4R60 A;  2BN7 A;  2P9A A;  4JUQ A;  2EVM A;  1PV9 A;  4FO8 A;  4EGE A;  5CE6 A;  4IKS A;  2B3K A;  5FCH A;  5JFR A;  2G6P A;  1KQ9 A;  1B6A A;  1XGS A;  2V3Y A;  3FMQ A;  2Q95 A;  1C23 A;  1W2M A;  5D6E A;  5FCF A;  3PKD A;  4S2T P;  2BWY A;  5JHU A;  5CDE A;  2BHD A;  4U6W A;  4ZWO A;  4IDY A;  1YW7 A;  1QXZ A;  2GG5 A;  4U6C A;  1Y1N A;  1O0X A;  2Q92 A;  3RVA A;  4ZWU A;  2GGB A;  4IPA A;  4ZNG A;  1B59 A;  3FMR A;  4FLK A;  3PKA A;  4B28 A;  1WBQ A;  2Q94 A;  4S2R P;  2BWX A;  5CDV A;  2ADU A;  3PKB A;  4RGZ 1;  4U1B A;  1A16 A;  4QR8 A;  2GU5 A;  4U6Z A;  3TB5 A;  1N51 A;  2BWU A;  2ZSG A;  2P99 A;  4MAT A;  3MR1 A;  2DFI A;  1KP0 A;  3BIQ A;  4OOK A;  1QXY A;  1KQ0 A;  4FLI A;  2GTX A;  2Q8K A;  4RZY A;  3CB6 A;  2GG9 A;  2GU6 A;  3PKE A;  2BB7 A;  3Q6D A;  5CIK A;  3S6B A;  4U6J A;  5JI6 A;  2P98 A;  5CDL A;  2EA2 A;  2GG3 A;  3CTZ A;  4HXX A;  4S00 A;  2GU7 A;  2OAZ A;  5CLS A;  1QZY A;  1JAW A;  3PKC A;  5D6F A;  2EA4 A;  1CHM A;  4A6W A;  4FLJ A;  3BIT A;  4IKT A;  1YW9 A;  1M35 A;  2EVO A;  1R5G A;  4IKR A;  1XGO A;  5CNX A;  2GZ5 A;  4PNC A;  2B3H A;  2Q93 A;  2GG2 A;  4PV4 A;  2GGC A;  2IW2 A;  1R5H A; 
#chains in the Genus database with same CATH homology
 4FUK A;  2BH3 A;  4U73 A;  2V3X A;  2NQ7 A;  3TAV A;  3IU8 A;  2GG0 A;  2V3Z A;  3IU7 A;  1MAT A;  4IU6 A;  4RZZ A;  2BHA A;  1XNZ A;  1YVM A;  3FM3 A;  2BWV A;  3L7G A;  4U6E A;  2BWT A;  2GG8 A;  3L24 A;  5E5B A;  1WL6 A;  3MX6 A;  1C24 A;  1C21 A;  1R58 A;  1W7V A;  4FLL A;  1WKM A;  4U70 A;  1BN5 A;  1C27 A;  2GG7 A;  4Z7M A;  2OKN A;  3BIP A;  2BWW A;  1WN1 A;  2EVC A;  4ZWP A;  2BWS A;  2BHB A;  3D27 A;  2Q96 A;  2MAT A;  2NQ6 A;  3IG4 A;  4IF7 A;  1XGN A;  3MAT A;  1BOA A;  1C22 A;  2GA2 A;  4U75 A;  4FO7 A;  2BHC A;  4FKC A;  4U69 A;  1WL9 A;  1YW8 A;  1QXW A;  4IEC A;  4U76 A;  4IKU A;  1WY2 A;  2GU4 A;  2HOW A;  1WLR A;  3IU9 A;  2B3L A;  2V6C A;  4S01 A;  3ROR A;  4KM3 A;  4U71 A;  4A6V A;  3CB5 A;  1YJ3 A;  1XGM A;  4R60 A;  2BN7 A;  2P9A A;  4JUQ A;  2EVM A;  1PV9 A;  4FO8 A;  4EGE A;  5CE6 A;  4IKS A;  2B3K A;  5FCH A;  5JFR A;  2G6P A;  1KQ9 A;  1B6A A;  1XGS A;  2V3Y A;  3FMQ A;  2Q95 A;  1C23 A;  1W2M A;  5D6E A;  5FCF A;  3PKD A;  4S2T P;  2BWY A;  5JHU A;  5CDE A;  2BHD A;  4U6W A;  4ZWO A;  4IDY A;  1YW7 A;  1QXZ A;  2GG5 A;  4U6C A;  1Y1N A;  1O0X A;  2Q92 A;  3RVA A;  4ZWU A;  2GGB A;  4IPA A;  4ZNG A;  1B59 A;  3FMR A;  4FLK A;  3PKA A;  4B28 A;  1WBQ A;  2Q94 A;  4S2R P;  2BWX A;  5CDV A;  2ADU A;  3PKB A;  4RGZ 1;  4U1B A;  1A16 A;  4QR8 A;  2GU5 A;  4U6Z A;  3TB5 A;  1N51 A;  2BWU A;  2ZSG A;  2P99 A;  4MAT A;  3MR1 A;  2DFI A;  1KP0 A;  3BIQ A;  4OOK A;  1QXY A;  1KQ0 A;  4FLI A;  2GTX A;  2Q8K A;  4RZY A;  3CB6 A;  2GG9 A;  2GU6 A;  3PKE A;  2BB7 A;  3Q6D A;  5CIK A;  3S6B A;  4U6J A;  5JI6 A;  2P98 A;  5CDL A;  2EA2 A;  2GG3 A;  3CTZ A;  4HXX A;  4S00 A;  2GU7 A;  2OAZ A;  5CLS A;  1QZY A;  1JAW A;  3PKC A;  5D6F A;  2EA4 A;  1CHM A;  4A6W A;  4FLJ A;  3BIT A;  4IKT A;  1YW9 A;  1M35 A;  2EVO A;  1R5G A;  4IKR A;  1XGO A;  5CNX A;  2GZ5 A;  4PNC A;  2B3H A;  2Q93 A;  2GG2 A;  4PV4 A;  2GGC A;  2IW2 A;  1R5H A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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