4U73A

Hsmetap(f309m) in complex with (amino(phenyl)methyl)phosphonic acid
Total Genus 99
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
304
structure length
304
Chain Sequence
YRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLMHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
pubmed doi rcsb
molecule keywords Methionine aminopeptidase 1
molecule tags Hydrolase
source organism Homo sapiens
total genus 99
structure length 304
sequence length 304
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2014-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4u73A00
2GU6A 1WBQA 2ZSGA 2EVCA 1WL9A 3CB5A 2GU7A 2GG9A 2GG0A 2Q92A 3PKDA 5CDVA 2GA2A 5JHUA 2V6CA 1QZYA 1WN1A 4S01A 3MATA 4A6VA 4IECA 5CDLA 4U71A 2BWTA 4FLJA 4IDYA 5E5BA 3IG4A 4OOKA 2OAZA 2Q94A 5CDEA 4U70A 1C23A 3L7GA 1YW8A 3BIPA 4A6WA 1WLRA 2G6PA 4EGEA 1R58A 2BWUA 4ZWUA 2EA2A 2MATA 4QR8A 2EVOA 4RGZ1 1WL6A 4IKTA 5FCFA 4ZWOA 4S2TP 4MATA 2B3LA 1C21A 4U75A 1XGOA 4IKRA 1M35A 4KM3A 1JAWA 4U6CA 2ADUA 2B3HA 3FM3A 4IU6A 1C22A 1CHMA 2GTXA 2NQ6A 3Q6DA 1WY2A 3MX6A 3CTZA 3PKAA 1QXYA 2GG3A 3MR1A 5D6FA 4FLKA 4S2RP 2GU4A 4RZZA 1YW9A 1YW7A 4RZYA 3BIQA 4U6ZA 2NQ7A 2BWSA 4U1BA 5CNXA 2GG7A 4IPAA 2BWYA 4S00A 2EVMA 1KP0A 3CB6A 3IU9A 3BITA 1KQ0A 1PV9A 1XGSA 2GG5A 2GU5A 2V3ZA 5CLSA 1C27A 1R5GA 2GZ5A 3FMQA 3S6BA 2P99A 1QXWA 1XNZA 4FLIA 4FO8A 4U6JA 2BN7A 4Z7MA 2V3YA 5JI6A 4U6WA 1BOAA 4FUKA 1QXZA 4B28A 1YVMA 2DFIA 4FLLA 5CIKA 2EA4A 3PKEA 2BHAA 1N51A 1A16A 1YJ3A 2BH3A 1BN5A 2HOWA 1W7VA 4ZNGA 4U73A 1R5HA 2IW2A 2V3XA 4IF7A 2GG2A 4FKCA 2GG8A 3PKCA 4PV4A 1O0XA 1MATA 3IU8A 3PKBA 2BWXA 1C24A 1XGMA 2Q96A 4FO7A 4U6EA 4ZWPA 1B59A 4IKUA 1W2MA 2P9AA 2BHDA 3IU7A 3TAVA 2Q95A 4JUQA 2Q93A 4R60A 2BWVA 4PNCA 3FMRA 4IKSA 2B3KA 4U76A 2BHCA 2GGBA 5D6EA 5CE6A 4HXXA 3L24A 3RORA 2BWWA 4U69A 2OKNA 5JFRA 1B6AA 2BB7A 3TB5A 3RVAA 1KQ9A 1Y1NA 3D27A 2P98A 5FCHA 2BHBA 2Q8KA 2GGCA 1WKMA 1XGNA
chains in the Genus database with same CATH superfamily
2GU6A 1WBQA 2ZSGA 2EVCA 1WL9A 3CB5A 2GU7A 2GG9A 2GG0A 2Q92A 3PKDA 5CDVA 2GA2A 5JHUA 2V6CA 1QZYA 1WN1A 4S01A 3MATA 4A6VA 4IECA 5CDLA 4U71A 2BWTA 4FLJA 4IDYA 5E5BA 3IG4A 4OOKA 2OAZA 2Q94A 5CDEA 4U70A 1C23A 3L7GA 1YW8A 3BIPA 4A6WA 1WLRA 2G6PA 4EGEA 1R58A 2BWUA 4ZWUA 2EA2A 2MATA 4QR8A 2EVOA 4RGZ1 1WL6A 4IKTA 5FCFA 4ZWOA 4S2TP 4MATA 2B3LA 1C21A 4U75A 1XGOA 4IKRA 1M35A 4KM3A 1JAWA 4U6CA 2ADUA 2B3HA 3FM3A 4IU6A 1C22A 1CHMA 2GTXA 2NQ6A 3Q6DA 1WY2A 3MX6A 3CTZA 3PKAA 1QXYA 2GG3A 3MR1A 5D6FA 4FLKA 4S2RP 2GU4A 4RZZA 1YW9A 1YW7A 4RZYA 3BIQA 4U6ZA 2NQ7A 2BWSA 4U1BA 5CNXA 2GG7A 4IPAA 2BWYA 4S00A 2EVMA 1KP0A 3CB6A 3IU9A 3BITA 1KQ0A 1PV9A 1XGSA 2GG5A 2GU5A 2V3ZA 5CLSA 1C27A 1R5GA 2GZ5A 3FMQA 3S6BA 2P99A 1QXWA 1XNZA 4FLIA 4FO8A 4U6JA 2BN7A 4Z7MA 2V3YA 5JI6A 4U6WA 1BOAA 4FUKA 1QXZA 4B28A 1YVMA 2DFIA 4FLLA 5CIKA 2EA4A 3PKEA 2BHAA 1N51A 1A16A 1YJ3A 2BH3A 1BN5A 2HOWA 1W7VA 4ZNGA 4U73A 1R5HA 2IW2A 2V3XA 4IF7A 2GG2A 4FKCA 2GG8A 3PKCA 4PV4A 1O0XA 1MATA 3IU8A 3PKBA 2BWXA 1C24A 1XGMA 2Q96A 4FO7A 4U6EA 4ZWPA 1B59A 4IKUA 1W2MA 2P9AA 2BHDA 3IU7A 3TAVA 2Q95A 4JUQA 2Q93A 4R60A 2BWVA 4PNCA 3FMRA 4IKSA 2B3KA 4U76A 2BHCA 2GGBA 5D6EA 5CE6A 4HXXA 3L24A 3RORA 2BWWA 4U69A 2OKNA 5JFRA 1B6AA 2BB7A 3TB5A 3RVAA 1KQ9A 1Y1NA 3D27A 2P98A 5FCHA 2BHBA 2Q8KA 2GGCA 1WKMA 1XGNA
chains in the Genus database with same CATH topology
2GU6A 1WBQA 2ZSGA 2EVCA 1WL9A 3CB5A 2GU7A 2GG9A 2GG0A 2Q92A 3PKDA 5CDVA 2GA2A 5JHUA 2V6CA 1QZYA 1WN1A 4S01A 3MATA 4A6VA 4IECA 5CDLA 4U71A 2BWTA 4FLJA 4IDYA 5E5BA 3IG4A 4OOKA 2OAZA 2Q94A 5CDEA 4U70A 1C23A 3L7GA 1YW8A 3BIPA 4A6WA 1WLRA 2G6PA 4EGEA 1R58A 2BWUA 4ZWUA 2EA2A 2MATA 4QR8A 2EVOA 4RGZ1 1WL6A 4IKTA 5FCFA 4ZWOA 4S2TP 4MATA 2B3LA 1C21A 4U75A 1XGOA 4IKRA 1M35A 4KM3A 1JAWA 4U6CA 2ADUA 2B3HA 3FM3A 4IU6A 1C22A 1CHMA 2GTXA 2NQ6A 3Q6DA 1WY2A 3MX6A 3CTZA 3PKAA 1QXYA 2GG3A 3MR1A 5D6FA 4FLKA 4S2RP 2GU4A 4RZZA 1YW9A 1YW7A 4RZYA 3BIQA 4U6ZA 2NQ7A 2BWSA 4U1BA 5CNXA 2GG7A 4IPAA 2BWYA 4S00A 2EVMA 1KP0A 3CB6A 3IU9A 3BITA 1KQ0A 1PV9A 1XGSA 2GG5A 2GU5A 2V3ZA 5CLSA 1C27A 1R5GA 2GZ5A 3FMQA 3S6BA 2P99A 1QXWA 1XNZA 4FLIA 4FO8A 4U6JA 2BN7A 4Z7MA 2V3YA 5JI6A 4U6WA 1BOAA 4FUKA 1QXZA 4B28A 1YVMA 2DFIA 4FLLA 5CIKA 2EA4A 3PKEA 2BHAA 1N51A 1A16A 1YJ3A 2BH3A 1BN5A 2HOWA 1W7VA 4ZNGA 4U73A 1R5HA 2IW2A 2V3XA 4IF7A 2GG2A 4FKCA 2GG8A 3PKCA 4PV4A 1O0XA 1MATA 3IU8A 3PKBA 2BWXA 1C24A 1XGMA 2Q96A 4FO7A 4U6EA 4ZWPA 1B59A 4IKUA 1W2MA 2P9AA 2BHDA 3IU7A 3TAVA 2Q95A 4JUQA 2Q93A 4R60A 2BWVA 4PNCA 3FMRA 4IKSA 2B3KA 4U76A 2BHCA 2GGBA 5D6EA 5CE6A 4HXXA 3L24A 3RORA 2BWWA 4U69A 2OKNA 5JFRA 1B6AA 2BB7A 3TB5A 3RVAA 1KQ9A 1Y1NA 3D27A 2P98A 5FCHA 2BHBA 2Q8KA 2GGCA 1WKMA 1XGNA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2GU6 A;  1WBQ A;  2ZSG A;  2EVC A;  1WL9 A;  3CB5 A;  2GU7 A;  2GG9 A;  2GG0 A;  2Q92 A;  3PKD A;  5CDV A;  2GA2 A;  5JHU A;  2V6C A;  1QZY A;  1WN1 A;  4S01 A;  3MAT A;  4A6V A;  4IEC A;  5CDL A;  4U71 A;  2BWT A;  4FLJ A;  4IDY A;  5E5B A;  3IG4 A;  4OOK A;  2OAZ A;  2Q94 A;  5CDE A;  4U70 A;  1C23 A;  3L7G A;  1YW8 A;  3BIP A;  4A6W A;  1WLR A;  2G6P A;  4EGE A;  1R58 A;  2BWU A;  4ZWU A;  2EA2 A;  2MAT A;  4QR8 A;  2EVO A;  4RGZ 1;  1WL6 A;  4IKT A;  5FCF A;  4ZWO A;  4S2T P;  4MAT A;  2B3L A;  1C21 A;  4U75 A;  1XGO A;  4IKR A;  1M35 A;  4KM3 A;  1JAW A;  4U6C A;  2ADU A;  2B3H A;  3FM3 A;  4IU6 A;  1C22 A;  1CHM A;  2GTX A;  2NQ6 A;  3Q6D A;  1WY2 A;  3MX6 A;  3CTZ A;  3PKA A;  1QXY A;  2GG3 A;  3MR1 A;  5D6F A;  4FLK A;  4S2R P;  2GU4 A;  4RZZ A;  1YW9 A;  1YW7 A;  4RZY A;  3BIQ A;  4U6Z A;  2NQ7 A;  2BWS A;  4U1B A;  5CNX A;  2GG7 A;  4IPA A;  2BWY A;  4S00 A;  2EVM A;  1KP0 A;  3CB6 A;  3IU9 A;  3BIT A;  1KQ0 A;  1PV9 A;  1XGS A;  2GG5 A;  2GU5 A;  2V3Z A;  5CLS A;  1C27 A;  1R5G A;  2GZ5 A;  3FMQ A;  3S6B A;  2P99 A;  1QXW A;  1XNZ A;  4FLI A;  4FO8 A;  4U6J A;  2BN7 A;  4Z7M A;  2V3Y A;  5JI6 A;  4U6W A;  1BOA A;  4FUK A;  1QXZ A;  4B28 A;  1YVM A;  2DFI A;  4FLL A;  5CIK A;  2EA4 A;  3PKE A;  2BHA A;  1N51 A;  1A16 A;  1YJ3 A;  2BH3 A;  1BN5 A;  2HOW A;  1W7V A;  4ZNG A;  4U73 A;  1R5H A;  2IW2 A;  2V3X A;  4IF7 A;  2GG2 A;  4FKC A;  2GG8 A;  3PKC A;  4PV4 A;  1O0X A;  1MAT A;  3IU8 A;  3PKB A;  2BWX A;  1C24 A;  1XGM A;  2Q96 A;  4FO7 A;  4U6E A;  4ZWP A;  1B59 A;  4IKU A;  1W2M A;  2P9A A;  2BHD A;  3IU7 A;  3TAV A;  2Q95 A;  4JUQ A;  2Q93 A;  4R60 A;  2BWV A;  4PNC A;  3FMR A;  4IKS A;  2B3K A;  4U76 A;  2BHC A;  2GGB A;  5D6E A;  5CE6 A;  4HXX A;  3L24 A;  3ROR A;  2BWW A;  4U69 A;  2OKN A;  5JFR A;  1B6A A;  2BB7 A;  3TB5 A;  3RVA A;  1KQ9 A;  1Y1N A;  3D27 A;  2P98 A;  5FCH A;  2BHB A;  2Q8K A;  2GGC A;  1WKM A;  1XGN A; 
#chains in the Genus database with same CATH topology
 2GU6 A;  1WBQ A;  2ZSG A;  2EVC A;  1WL9 A;  3CB5 A;  2GU7 A;  2GG9 A;  2GG0 A;  2Q92 A;  3PKD A;  5CDV A;  2GA2 A;  5JHU A;  2V6C A;  1QZY A;  1WN1 A;  4S01 A;  3MAT A;  4A6V A;  4IEC A;  5CDL A;  4U71 A;  2BWT A;  4FLJ A;  4IDY A;  5E5B A;  3IG4 A;  4OOK A;  2OAZ A;  2Q94 A;  5CDE A;  4U70 A;  1C23 A;  3L7G A;  1YW8 A;  3BIP A;  4A6W A;  1WLR A;  2G6P A;  4EGE A;  1R58 A;  2BWU A;  4ZWU A;  2EA2 A;  2MAT A;  4QR8 A;  2EVO A;  4RGZ 1;  1WL6 A;  4IKT A;  5FCF A;  4ZWO A;  4S2T P;  4MAT A;  2B3L A;  1C21 A;  4U75 A;  1XGO A;  4IKR A;  1M35 A;  4KM3 A;  1JAW A;  4U6C A;  2ADU A;  2B3H A;  3FM3 A;  4IU6 A;  1C22 A;  1CHM A;  2GTX A;  2NQ6 A;  3Q6D A;  1WY2 A;  3MX6 A;  3CTZ A;  3PKA A;  1QXY A;  2GG3 A;  3MR1 A;  5D6F A;  4FLK A;  4S2R P;  2GU4 A;  4RZZ A;  1YW9 A;  1YW7 A;  4RZY A;  3BIQ A;  4U6Z A;  2NQ7 A;  2BWS A;  4U1B A;  5CNX A;  2GG7 A;  4IPA A;  2BWY A;  4S00 A;  2EVM A;  1KP0 A;  3CB6 A;  3IU9 A;  3BIT A;  1KQ0 A;  1PV9 A;  1XGS A;  2GG5 A;  2GU5 A;  2V3Z A;  5CLS A;  1C27 A;  1R5G A;  2GZ5 A;  3FMQ A;  3S6B A;  2P99 A;  1QXW A;  1XNZ A;  4FLI A;  4FO8 A;  4U6J A;  2BN7 A;  4Z7M A;  2V3Y A;  5JI6 A;  4U6W A;  1BOA A;  4FUK A;  1QXZ A;  4B28 A;  1YVM A;  2DFI A;  4FLL A;  5CIK A;  2EA4 A;  3PKE A;  2BHA A;  1N51 A;  1A16 A;  1YJ3 A;  2BH3 A;  1BN5 A;  2HOW A;  1W7V A;  4ZNG A;  4U73 A;  1R5H A;  2IW2 A;  2V3X A;  4IF7 A;  2GG2 A;  4FKC A;  2GG8 A;  3PKC A;  4PV4 A;  1O0X A;  1MAT A;  3IU8 A;  3PKB A;  2BWX A;  1C24 A;  1XGM A;  2Q96 A;  4FO7 A;  4U6E A;  4ZWP A;  1B59 A;  4IKU A;  1W2M A;  2P9A A;  2BHD A;  3IU7 A;  3TAV A;  2Q95 A;  4JUQ A;  2Q93 A;  4R60 A;  2BWV A;  4PNC A;  3FMR A;  4IKS A;  2B3K A;  4U76 A;  2BHC A;  2GGB A;  5D6E A;  5CE6 A;  4HXX A;  3L24 A;  3ROR A;  2BWW A;  4U69 A;  2OKN A;  5JFR A;  1B6A A;  2BB7 A;  3TB5 A;  3RVA A;  1KQ9 A;  1Y1N A;  3D27 A;  2P98 A;  5FCH A;  2BHB A;  2Q8K A;  2GGC A;  1WKM A;  1XGN A; 
#chains in the Genus database with same CATH homology
 2GU6 A;  1WBQ A;  2ZSG A;  2EVC A;  1WL9 A;  3CB5 A;  2GU7 A;  2GG9 A;  2GG0 A;  2Q92 A;  3PKD A;  5CDV A;  2GA2 A;  5JHU A;  2V6C A;  1QZY A;  1WN1 A;  4S01 A;  3MAT A;  4A6V A;  4IEC A;  5CDL A;  4U71 A;  2BWT A;  4FLJ A;  4IDY A;  5E5B A;  3IG4 A;  4OOK A;  2OAZ A;  2Q94 A;  5CDE A;  4U70 A;  1C23 A;  3L7G A;  1YW8 A;  3BIP A;  4A6W A;  1WLR A;  2G6P A;  4EGE A;  1R58 A;  2BWU A;  4ZWU A;  2EA2 A;  2MAT A;  4QR8 A;  2EVO A;  4RGZ 1;  1WL6 A;  4IKT A;  5FCF A;  4ZWO A;  4S2T P;  4MAT A;  2B3L A;  1C21 A;  4U75 A;  1XGO A;  4IKR A;  1M35 A;  4KM3 A;  1JAW A;  4U6C A;  2ADU A;  2B3H A;  3FM3 A;  4IU6 A;  1C22 A;  1CHM A;  2GTX A;  2NQ6 A;  3Q6D A;  1WY2 A;  3MX6 A;  3CTZ A;  3PKA A;  1QXY A;  2GG3 A;  3MR1 A;  5D6F A;  4FLK A;  4S2R P;  2GU4 A;  4RZZ A;  1YW9 A;  1YW7 A;  4RZY A;  3BIQ A;  4U6Z A;  2NQ7 A;  2BWS A;  4U1B A;  5CNX A;  2GG7 A;  4IPA A;  2BWY A;  4S00 A;  2EVM A;  1KP0 A;  3CB6 A;  3IU9 A;  3BIT A;  1KQ0 A;  1PV9 A;  1XGS A;  2GG5 A;  2GU5 A;  2V3Z A;  5CLS A;  1C27 A;  1R5G A;  2GZ5 A;  3FMQ A;  3S6B A;  2P99 A;  1QXW A;  1XNZ A;  4FLI A;  4FO8 A;  4U6J A;  2BN7 A;  4Z7M A;  2V3Y A;  5JI6 A;  4U6W A;  1BOA A;  4FUK A;  1QXZ A;  4B28 A;  1YVM A;  2DFI A;  4FLL A;  5CIK A;  2EA4 A;  3PKE A;  2BHA A;  1N51 A;  1A16 A;  1YJ3 A;  2BH3 A;  1BN5 A;  2HOW A;  1W7V A;  4ZNG A;  4U73 A;  1R5H A;  2IW2 A;  2V3X A;  4IF7 A;  2GG2 A;  4FKC A;  2GG8 A;  3PKC A;  4PV4 A;  1O0X A;  1MAT A;  3IU8 A;  3PKB A;  2BWX A;  1C24 A;  1XGM A;  2Q96 A;  4FO7 A;  4U6E A;  4ZWP A;  1B59 A;  4IKU A;  1W2M A;  2P9A A;  2BHD A;  3IU7 A;  3TAV A;  2Q95 A;  4JUQ A;  2Q93 A;  4R60 A;  2BWV A;  4PNC A;  3FMR A;  4IKS A;  2B3K A;  4U76 A;  2BHC A;  2GGB A;  5D6E A;  5CE6 A;  4HXX A;  3L24 A;  3ROR A;  2BWW A;  4U69 A;  2OKN A;  5JFR A;  1B6A A;  2BB7 A;  3TB5 A;  3RVA A;  1KQ9 A;  1Y1N A;  3D27 A;  2P98 A;  5FCH A;  2BHB A;  2Q8K A;  2GGC A;  1WKM A;  1XGN A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite