4A6VA

X-ray structures of oxazole hydroxamate ecmetap-mn complexes
Total Genus 86

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
264
structure length
264
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDEA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTII5 (196-199)AH1 (8-28)S19 (244-247)AH2 (38-52)TI8 (251-254)TII1 (33-36)S1 (36-37)TI2 (83-86)S2 (56-57)TI1 (57-60)S6 (92-102)TII2 (59-62)3H2 (62-64)S3 (69-73)TII'1 (73-76)TII3 (89-92)S16 (223-225)S5 (87-88)S17 (231-233)TIV1 (101-104)S7 (105-115)TIV2 (173-176)S18 (236-241)AH3 (120-139)AH4 (146-160)TII4 (141-144)S9 (163-164)TI3 (165-168)S11 (182-183)S10 (170-172)TVIII2 (176-179)S12 (194-195)S13 (199-203)S14 (206-208)TIV3 (208-211)S15 (214-216)TI5 (217-220)TIV4 (219-222)TI6 (225-228)TI7 (247-250)TIV5 (241-244)S20 (259-261)TVIII3 (257-260)3H1 (29-31)S4 (76-78)S8 (144-145)TI4 (188-191)Updating...
connected with : NaN
molecule tags Hydrolase
publication title Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
pubmed doi rcsb
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 86
structure length 264
sequence length 264
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4a6vA00
4JUQA 1YW9A 4IU6A 4U6EA 2B3LA 2V3XA 1C24A 3TB5A 3PKEA 5JHUA 3MX6A 2P99A 3Q6DA 1XGNA 4U6CA 2Q8KA 3RVAA 4A6WA 3PKDA 4U6WA 1KQ0A 2GTXA 4U71A 1KP0A 2GGCA 2BN7A 3FMQA 5FCHA 1PV9A 2GG7A 1QZYA 2Q92A 4FKCA 1WY2A 1C22A 2V3YA 2B3HA 3MATA 3CB6A 4IF7A 2BWYA 4U69A 4U6JA 4EGEA 4FLIA 4Z7MA 5CNXA 5CIKA 4PNCA 1MATA 5CE6A 1WBQA 4RZZA 4S00A 4FLJA 1WLRA 2GU7A 4R60A 3L7GA 2V6CA 3BIQA 4ZWUA 1C27A 5E5BA 1XGSA 4FLKA 4IDYA 2ZSGA 1CHMA 3IU9A 1YVMA 5CDLA 2IW2A 5FCFA 3BIPA 4U73A 1WKMA 1B59A 1B6AA 1XGMA 2GG8A 2P9AA 3TAVA 3FM3A 2DFIA 4PV4A 4U6ZA 3S6BA 4HXXA 1N51A 2BWTA 2GU5A 1WL9A 2BWUA 2BWVA 2EA4A 2GGBA 2Q95A 1BOAA 4KM3A 2BHDA 1R5HA 4MATA 4FLLA 4IECA 2BHBA 4RZYA 1QXZA 1QXYA 5JI6A 2GG9A 3CB5A 2BH3A 4U70A 4ZNGA 3IU8A 2OKNA 2GA2A 2EVMA 4QR8A 2G6PA 1W7VA 2ADUA 4ZWPA 2GG2A 2Q96A 2BHAA 4IKTA 2GZ5A 2BB7A 1YJ3A 1WN1A 1XNZA 2GG0A 3IU7A 2NQ7A 1C21A 4S2RP 4U75A 5CDEA 2GG5A 2GG3A 2Q93A 1M35A 5CDVA 1O0XA 3MR1A 5D6EA 2Q94A 2MATA 5JFRA 1R5GA 4S2TP 4ZWOA 1A16A 2OAZA 5CLSA 3RORA 1YW8A 4OOKA 1C23A 2BWSA 2GU6A 4U1BA 4FO7A 2EVCA 3BITA 1XGOA 4FO8A 1W2MA 4B28A 1QXWA 3L24A 5D6FA 2NQ6A 1BN5A 3D27A 2BWWA 4A6VA 2EVOA 1WL6A 3PKAA 4IKUA 1YW7A 4S01A 2B3KA 2P98A 3PKCA 2BWXA 2V3ZA 4RGZ1 3FMRA 4FUKA 3IG4A 4IPAA 2EA2A 1JAWA 1Y1NA 2GU4A 1R58A 2HOWA 1KQ9A 3CTZA 4IKRA 4IKSA 4U76A 2BHCA 3PKBA
chains in the Genus database with same CATH superfamily
4JUQA 1YW9A 4IU6A 4U6EA 2B3LA 2V3XA 1C24A 3TB5A 3PKEA 5JHUA 3MX6A 2P99A 3Q6DA 1XGNA 4U6CA 2Q8KA 3RVAA 4A6WA 3PKDA 4U6WA 1KQ0A 2GTXA 4U71A 1KP0A 2GGCA 2BN7A 3FMQA 5FCHA 1PV9A 2GG7A 1QZYA 2Q92A 4FKCA 1WY2A 1C22A 2V3YA 2B3HA 3MATA 3CB6A 4IF7A 2BWYA 4U69A 4U6JA 4EGEA 4FLIA 4Z7MA 5CNXA 5CIKA 4PNCA 1MATA 5CE6A 1WBQA 4RZZA 4S00A 4FLJA 1WLRA 2GU7A 4R60A 3L7GA 2V6CA 3BIQA 4ZWUA 1C27A 5E5BA 1XGSA 4FLKA 4IDYA 2ZSGA 1CHMA 3IU9A 1YVMA 5CDLA 2IW2A 5FCFA 3BIPA 4U73A 1WKMA 1B59A 1B6AA 1XGMA 2GG8A 2P9AA 3TAVA 3FM3A 2DFIA 4PV4A 4U6ZA 3S6BA 4HXXA 1N51A 2BWTA 2GU5A 1WL9A 2BWUA 2BWVA 2EA4A 2GGBA 2Q95A 1BOAA 4KM3A 2BHDA 1R5HA 4MATA 4FLLA 4IECA 2BHBA 4RZYA 1QXZA 1QXYA 5JI6A 2GG9A 3CB5A 2BH3A 4U70A 4ZNGA 3IU8A 2OKNA 2GA2A 2EVMA 4QR8A 2G6PA 1W7VA 2ADUA 4ZWPA 2GG2A 2Q96A 2BHAA 4IKTA 2GZ5A 2BB7A 1YJ3A 1WN1A 1XNZA 2GG0A 3IU7A 2NQ7A 1C21A 4S2RP 4U75A 5CDEA 2GG5A 2GG3A 2Q93A 1M35A 5CDVA 1O0XA 3MR1A 5D6EA 2Q94A 2MATA 5JFRA 1R5GA 4S2TP 4ZWOA 1A16A 2OAZA 5CLSA 3RORA 1YW8A 4OOKA 1C23A 2BWSA 2GU6A 4U1BA 4FO7A 2EVCA 3BITA 1XGOA 4FO8A 1W2MA 4B28A 1QXWA 3L24A 5D6FA 2NQ6A 1BN5A 3D27A 2BWWA 4A6VA 2EVOA 1WL6A 3PKAA 4IKUA 1YW7A 4S01A 2B3KA 2P98A 3PKCA 2BWXA 2V3ZA 4RGZ1 3FMRA 4FUKA 3IG4A 4IPAA 2EA2A 1JAWA 1Y1NA 2GU4A 1R58A 2HOWA 1KQ9A 3CTZA 4IKRA 4IKSA 4U76A 2BHCA 3PKBA
chains in the Genus database with same CATH topology
4JUQA 1YW9A 4IU6A 4U6EA 2B3LA 2V3XA 1C24A 3TB5A 3PKEA 5JHUA 3MX6A 2P99A 3Q6DA 1XGNA 4U6CA 2Q8KA 3RVAA 4A6WA 3PKDA 4U6WA 1KQ0A 2GTXA 4U71A 1KP0A 2GGCA 2BN7A 3FMQA 5FCHA 1PV9A 2GG7A 1QZYA 2Q92A 4FKCA 1WY2A 1C22A 2V3YA 2B3HA 3MATA 3CB6A 4IF7A 2BWYA 4U69A 4U6JA 4EGEA 4FLIA 4Z7MA 5CNXA 5CIKA 4PNCA 1MATA 5CE6A 1WBQA 4RZZA 4S00A 4FLJA 1WLRA 2GU7A 4R60A 3L7GA 2V6CA 3BIQA 4ZWUA 1C27A 5E5BA 1XGSA 4FLKA 4IDYA 2ZSGA 1CHMA 3IU9A 1YVMA 5CDLA 2IW2A 5FCFA 3BIPA 4U73A 1WKMA 1B59A 1B6AA 1XGMA 2GG8A 2P9AA 3TAVA 3FM3A 2DFIA 4PV4A 4U6ZA 3S6BA 4HXXA 1N51A 2BWTA 2GU5A 1WL9A 2BWUA 2BWVA 2EA4A 2GGBA 2Q95A 1BOAA 4KM3A 2BHDA 1R5HA 4MATA 4FLLA 4IECA 2BHBA 4RZYA 1QXZA 1QXYA 5JI6A 2GG9A 3CB5A 2BH3A 4U70A 4ZNGA 3IU8A 2OKNA 2GA2A 2EVMA 4QR8A 2G6PA 1W7VA 2ADUA 4ZWPA 2GG2A 2Q96A 2BHAA 4IKTA 2GZ5A 2BB7A 1YJ3A 1WN1A 1XNZA 2GG0A 3IU7A 2NQ7A 1C21A 4S2RP 4U75A 5CDEA 2GG5A 2GG3A 2Q93A 1M35A 5CDVA 1O0XA 3MR1A 5D6EA 2Q94A 2MATA 5JFRA 1R5GA 4S2TP 4ZWOA 1A16A 2OAZA 5CLSA 3RORA 1YW8A 4OOKA 1C23A 2BWSA 2GU6A 4U1BA 4FO7A 2EVCA 3BITA 1XGOA 4FO8A 1W2MA 4B28A 1QXWA 3L24A 5D6FA 2NQ6A 1BN5A 3D27A 2BWWA 4A6VA 2EVOA 1WL6A 3PKAA 4IKUA 1YW7A 4S01A 2B3KA 2P98A 3PKCA 2BWXA 2V3ZA 4RGZ1 3FMRA 4FUKA 3IG4A 4IPAA 2EA2A 1JAWA 1Y1NA 2GU4A 1R58A 2HOWA 1KQ9A 3CTZA 4IKRA 4IKSA 4U76A 2BHCA 3PKBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JUQ A;  1YW9 A;  4IU6 A;  4U6E A;  2B3L A;  2V3X A;  1C24 A;  3TB5 A;  3PKE A;  5JHU A;  3MX6 A;  2P99 A;  3Q6D A;  1XGN A;  4U6C A;  2Q8K A;  3RVA A;  4A6W A;  3PKD A;  4U6W A;  1KQ0 A;  2GTX A;  4U71 A;  1KP0 A;  2GGC A;  2BN7 A;  3FMQ A;  5FCH A;  1PV9 A;  2GG7 A;  1QZY A;  2Q92 A;  4FKC A;  1WY2 A;  1C22 A;  2V3Y A;  2B3H A;  3MAT A;  3CB6 A;  4IF7 A;  2BWY A;  4U69 A;  4U6J A;  4EGE A;  4FLI A;  4Z7M A;  5CNX A;  5CIK A;  4PNC A;  1MAT A;  5CE6 A;  1WBQ A;  4RZZ A;  4S00 A;  4FLJ A;  1WLR A;  2GU7 A;  4R60 A;  3L7G A;  2V6C A;  3BIQ A;  4ZWU A;  1C27 A;  5E5B A;  1XGS A;  4FLK A;  4IDY A;  2ZSG A;  1CHM A;  3IU9 A;  1YVM A;  5CDL A;  2IW2 A;  5FCF A;  3BIP A;  4U73 A;  1WKM A;  1B59 A;  1B6A A;  1XGM A;  2GG8 A;  2P9A A;  3TAV A;  3FM3 A;  2DFI A;  4PV4 A;  4U6Z A;  3S6B A;  4HXX A;  1N51 A;  2BWT A;  2GU5 A;  1WL9 A;  2BWU A;  2BWV A;  2EA4 A;  2GGB A;  2Q95 A;  1BOA A;  4KM3 A;  2BHD A;  1R5H A;  4MAT A;  4FLL A;  4IEC A;  2BHB A;  4RZY A;  1QXZ A;  1QXY A;  5JI6 A;  2GG9 A;  3CB5 A;  2BH3 A;  4U70 A;  4ZNG A;  3IU8 A;  2OKN A;  2GA2 A;  2EVM A;  4QR8 A;  2G6P A;  1W7V A;  2ADU A;  4ZWP A;  2GG2 A;  2Q96 A;  2BHA A;  4IKT A;  2GZ5 A;  2BB7 A;  1YJ3 A;  1WN1 A;  1XNZ A;  2GG0 A;  3IU7 A;  2NQ7 A;  1C21 A;  4S2R P;  4U75 A;  5CDE A;  2GG5 A;  2GG3 A;  2Q93 A;  1M35 A;  5CDV A;  1O0X A;  3MR1 A;  5D6E A;  2Q94 A;  2MAT A;  5JFR A;  1R5G A;  4S2T P;  4ZWO A;  1A16 A;  2OAZ A;  5CLS A;  3ROR A;  1YW8 A;  4OOK A;  1C23 A;  2BWS A;  2GU6 A;  4U1B A;  4FO7 A;  2EVC A;  3BIT A;  1XGO A;  4FO8 A;  1W2M A;  4B28 A;  1QXW A;  3L24 A;  5D6F A;  2NQ6 A;  1BN5 A;  3D27 A;  2BWW A;  4A6V A;  2EVO A;  1WL6 A;  3PKA A;  4IKU A;  1YW7 A;  4S01 A;  2B3K A;  2P98 A;  3PKC A;  2BWX A;  2V3Z A;  4RGZ 1;  3FMR A;  4FUK A;  3IG4 A;  4IPA A;  2EA2 A;  1JAW A;  1Y1N A;  2GU4 A;  1R58 A;  2HOW A;  1KQ9 A;  3CTZ A;  4IKR A;  4IKS A;  4U76 A;  2BHC A;  3PKB A; 
#chains in the Genus database with same CATH topology
 4JUQ A;  1YW9 A;  4IU6 A;  4U6E A;  2B3L A;  2V3X A;  1C24 A;  3TB5 A;  3PKE A;  5JHU A;  3MX6 A;  2P99 A;  3Q6D A;  1XGN A;  4U6C A;  2Q8K A;  3RVA A;  4A6W A;  3PKD A;  4U6W A;  1KQ0 A;  2GTX A;  4U71 A;  1KP0 A;  2GGC A;  2BN7 A;  3FMQ A;  5FCH A;  1PV9 A;  2GG7 A;  1QZY A;  2Q92 A;  4FKC A;  1WY2 A;  1C22 A;  2V3Y A;  2B3H A;  3MAT A;  3CB6 A;  4IF7 A;  2BWY A;  4U69 A;  4U6J A;  4EGE A;  4FLI A;  4Z7M A;  5CNX A;  5CIK A;  4PNC A;  1MAT A;  5CE6 A;  1WBQ A;  4RZZ A;  4S00 A;  4FLJ A;  1WLR A;  2GU7 A;  4R60 A;  3L7G A;  2V6C A;  3BIQ A;  4ZWU A;  1C27 A;  5E5B A;  1XGS A;  4FLK A;  4IDY A;  2ZSG A;  1CHM A;  3IU9 A;  1YVM A;  5CDL A;  2IW2 A;  5FCF A;  3BIP A;  4U73 A;  1WKM A;  1B59 A;  1B6A A;  1XGM A;  2GG8 A;  2P9A A;  3TAV A;  3FM3 A;  2DFI A;  4PV4 A;  4U6Z A;  3S6B A;  4HXX A;  1N51 A;  2BWT A;  2GU5 A;  1WL9 A;  2BWU A;  2BWV A;  2EA4 A;  2GGB A;  2Q95 A;  1BOA A;  4KM3 A;  2BHD A;  1R5H A;  4MAT A;  4FLL A;  4IEC A;  2BHB A;  4RZY A;  1QXZ A;  1QXY A;  5JI6 A;  2GG9 A;  3CB5 A;  2BH3 A;  4U70 A;  4ZNG A;  3IU8 A;  2OKN A;  2GA2 A;  2EVM A;  4QR8 A;  2G6P A;  1W7V A;  2ADU A;  4ZWP A;  2GG2 A;  2Q96 A;  2BHA A;  4IKT A;  2GZ5 A;  2BB7 A;  1YJ3 A;  1WN1 A;  1XNZ A;  2GG0 A;  3IU7 A;  2NQ7 A;  1C21 A;  4S2R P;  4U75 A;  5CDE A;  2GG5 A;  2GG3 A;  2Q93 A;  1M35 A;  5CDV A;  1O0X A;  3MR1 A;  5D6E A;  2Q94 A;  2MAT A;  5JFR A;  1R5G A;  4S2T P;  4ZWO A;  1A16 A;  2OAZ A;  5CLS A;  3ROR A;  1YW8 A;  4OOK A;  1C23 A;  2BWS A;  2GU6 A;  4U1B A;  4FO7 A;  2EVC A;  3BIT A;  1XGO A;  4FO8 A;  1W2M A;  4B28 A;  1QXW A;  3L24 A;  5D6F A;  2NQ6 A;  1BN5 A;  3D27 A;  2BWW A;  4A6V A;  2EVO A;  1WL6 A;  3PKA A;  4IKU A;  1YW7 A;  4S01 A;  2B3K A;  2P98 A;  3PKC A;  2BWX A;  2V3Z A;  4RGZ 1;  3FMR A;  4FUK A;  3IG4 A;  4IPA A;  2EA2 A;  1JAW A;  1Y1N A;  2GU4 A;  1R58 A;  2HOW A;  1KQ9 A;  3CTZ A;  4IKR A;  4IKS A;  4U76 A;  2BHC A;  3PKB A; 
#chains in the Genus database with same CATH homology
 4JUQ A;  1YW9 A;  4IU6 A;  4U6E A;  2B3L A;  2V3X A;  1C24 A;  3TB5 A;  3PKE A;  5JHU A;  3MX6 A;  2P99 A;  3Q6D A;  1XGN A;  4U6C A;  2Q8K A;  3RVA A;  4A6W A;  3PKD A;  4U6W A;  1KQ0 A;  2GTX A;  4U71 A;  1KP0 A;  2GGC A;  2BN7 A;  3FMQ A;  5FCH A;  1PV9 A;  2GG7 A;  1QZY A;  2Q92 A;  4FKC A;  1WY2 A;  1C22 A;  2V3Y A;  2B3H A;  3MAT A;  3CB6 A;  4IF7 A;  2BWY A;  4U69 A;  4U6J A;  4EGE A;  4FLI A;  4Z7M A;  5CNX A;  5CIK A;  4PNC A;  1MAT A;  5CE6 A;  1WBQ A;  4RZZ A;  4S00 A;  4FLJ A;  1WLR A;  2GU7 A;  4R60 A;  3L7G A;  2V6C A;  3BIQ A;  4ZWU A;  1C27 A;  5E5B A;  1XGS A;  4FLK A;  4IDY A;  2ZSG A;  1CHM A;  3IU9 A;  1YVM A;  5CDL A;  2IW2 A;  5FCF A;  3BIP A;  4U73 A;  1WKM A;  1B59 A;  1B6A A;  1XGM A;  2GG8 A;  2P9A A;  3TAV A;  3FM3 A;  2DFI A;  4PV4 A;  4U6Z A;  3S6B A;  4HXX A;  1N51 A;  2BWT A;  2GU5 A;  1WL9 A;  2BWU A;  2BWV A;  2EA4 A;  2GGB A;  2Q95 A;  1BOA A;  4KM3 A;  2BHD A;  1R5H A;  4MAT A;  4FLL A;  4IEC A;  2BHB A;  4RZY A;  1QXZ A;  1QXY A;  5JI6 A;  2GG9 A;  3CB5 A;  2BH3 A;  4U70 A;  4ZNG A;  3IU8 A;  2OKN A;  2GA2 A;  2EVM A;  4QR8 A;  2G6P A;  1W7V A;  2ADU A;  4ZWP A;  2GG2 A;  2Q96 A;  2BHA A;  4IKT A;  2GZ5 A;  2BB7 A;  1YJ3 A;  1WN1 A;  1XNZ A;  2GG0 A;  3IU7 A;  2NQ7 A;  1C21 A;  4S2R P;  4U75 A;  5CDE A;  2GG5 A;  2GG3 A;  2Q93 A;  1M35 A;  5CDV A;  1O0X A;  3MR1 A;  5D6E A;  2Q94 A;  2MAT A;  5JFR A;  1R5G A;  4S2T P;  4ZWO A;  1A16 A;  2OAZ A;  5CLS A;  3ROR A;  1YW8 A;  4OOK A;  1C23 A;  2BWS A;  2GU6 A;  4U1B A;  4FO7 A;  2EVC A;  3BIT A;  1XGO A;  4FO8 A;  1W2M A;  4B28 A;  1QXW A;  3L24 A;  5D6F A;  2NQ6 A;  1BN5 A;  3D27 A;  2BWW A;  4A6V A;  2EVO A;  1WL6 A;  3PKA A;  4IKU A;  1YW7 A;  4S01 A;  2B3K A;  2P98 A;  3PKC A;  2BWX A;  2V3Z A;  4RGZ 1;  3FMR A;  4FUK A;  3IG4 A;  4IPA A;  2EA2 A;  1JAW A;  1Y1N A;  2GU4 A;  1R58 A;  2HOW A;  1KQ9 A;  3CTZ A;  4IKR A;  4IKS A;  4U76 A;  2BHC A;  3PKB A; 
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