4A6WA

X-ray structures of oxazole hydroxamate ecmetap-mn complexes
Total Genus 83
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
pubmed doi rcsb
molecule keywords METHIONINE AMINOPEPTIDASE
molecule tags Transferase
total genus 83
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4a6wA00
3RORA 4U71A 1JAWA 3BITA 3BIPA 4B28A 2EVMA 4FKCA 4IKTA 2V3XA 3Q6DA 3MATA 3BIQA 4S2TP 2ZSGA 2V3ZA 4FLJA 2BHBA 3L7GA 4Z7MA 2EVCA 3IU8A 3MX6A 5JI6A 3CB5A 4PV4A 2GU6A 1MATA 4R60A 2BWVA 2GG3A 5JHUA 1O0XA 1QXYA 2Q92A 2OAZA 5CDVA 4IECA 1XGNA 2BHDA 4FUKA 1KQ0A 3CB6A 2Q93A 1M35A 2ADUA 2B3KA 1XGOA 1R5HA 3PKDA 2GU7A 5D6FA 1WL6A 2EVOA 4RZZA 1BOAA 4FO7A 1YJ3A 5JFRA 2GG8A 4FLKA 1B6AA 1XGMA 2OKNA 4U6CA 1R58A 4ZWPA 1C23A 3IU9A 1WL9A 4U70A 4IU6A 4U69A 4IPAA 2GG9A 1CHMA 2GG2A 5CIKA 2GTXA 5FCFA 3FM3A 4ZWOA 2GG0A 2P99A 5CDLA 3L24A 4A6WA 2HOWA 1Y1NA 4ZWUA 1XGSA 4IKRA 2EA4A 1R5GA 4MATA 4S2RP 4U73A 4JUQA 5E5BA 1QXZA 1KP0A 4IF7A 2G6PA 3TB5A 3MR1A 2BHAA 2NQ7A 3CTZA 2EA2A 1WKMA 2BB7A 2BWTA 2BH3A 1WBQA 3FMRA 1A16A 2GGCA 1XNZA 2P9AA 5D6EA 2GA2A 1W7VA 4U75A 1WY2A 3PKAA 2BWSA 1C24A 4ZNGA 2B3HA 4U6EA 1PV9A 3TAVA 4RZYA 2BWXA 5CLSA 2B3LA 4IKUA 2Q8KA 3FMQA 1N51A 1YW8A 3S6BA 5CDEA 3IU7A 1B59A 1YVMA 4RGZ1 2BWWA 3IG4A 1QZYA 1W2MA 3PKCA 2GG5A 2GG7A 1BN5A 4U6JA 2V3YA 4A6VA 2GU5A 2BWYA 2DFIA 4OOKA 3PKEA 5CNXA 2GGBA 4IDYA 4KM3A 2BN7A 4FLLA 2NQ6A 1C21A 2BHCA 2GU4A 1QXWA 4PNCA 1WN1A 4FO8A 4IKSA 3PKBA 1KQ9A 4U6WA 4QR8A 1YW9A 1C27A 2GZ5A 2Q96A 4FLIA 4S01A 3D27A 2Q94A 4S00A 2Q95A 2MATA 2V6CA 4HXXA 5FCHA 3RVAA 1YW7A 2P98A 5CE6A 1C22A 4U1BA 4U76A 2BWUA 4EGEA 1WLRA 2IW2A 4U6ZA
chains in the Genus database with same CATH superfamily
3RORA 4U71A 1JAWA 3BITA 3BIPA 4B28A 2EVMA 4FKCA 4IKTA 2V3XA 3Q6DA 3MATA 3BIQA 4S2TP 2ZSGA 2V3ZA 4FLJA 2BHBA 3L7GA 4Z7MA 2EVCA 3IU8A 3MX6A 5JI6A 3CB5A 4PV4A 2GU6A 1MATA 4R60A 2BWVA 2GG3A 5JHUA 1O0XA 1QXYA 2Q92A 2OAZA 5CDVA 4IECA 1XGNA 2BHDA 4FUKA 1KQ0A 3CB6A 2Q93A 1M35A 2ADUA 2B3KA 1XGOA 1R5HA 3PKDA 2GU7A 5D6FA 1WL6A 2EVOA 4RZZA 1BOAA 4FO7A 1YJ3A 5JFRA 2GG8A 4FLKA 1B6AA 1XGMA 2OKNA 4U6CA 1R58A 4ZWPA 1C23A 3IU9A 1WL9A 4U70A 4IU6A 4U69A 4IPAA 2GG9A 1CHMA 2GG2A 5CIKA 2GTXA 5FCFA 3FM3A 4ZWOA 2GG0A 2P99A 5CDLA 3L24A 4A6WA 2HOWA 1Y1NA 4ZWUA 1XGSA 4IKRA 2EA4A 1R5GA 4MATA 4S2RP 4U73A 4JUQA 5E5BA 1QXZA 1KP0A 4IF7A 2G6PA 3TB5A 3MR1A 2BHAA 2NQ7A 3CTZA 2EA2A 1WKMA 2BB7A 2BWTA 2BH3A 1WBQA 3FMRA 1A16A 2GGCA 1XNZA 2P9AA 5D6EA 2GA2A 1W7VA 4U75A 1WY2A 3PKAA 2BWSA 1C24A 4ZNGA 2B3HA 4U6EA 1PV9A 3TAVA 4RZYA 2BWXA 5CLSA 2B3LA 4IKUA 2Q8KA 3FMQA 1N51A 1YW8A 3S6BA 5CDEA 3IU7A 1B59A 1YVMA 4RGZ1 2BWWA 3IG4A 1QZYA 1W2MA 3PKCA 2GG5A 2GG7A 1BN5A 4U6JA 2V3YA 4A6VA 2GU5A 2BWYA 2DFIA 4OOKA 3PKEA 5CNXA 2GGBA 4IDYA 4KM3A 2BN7A 4FLLA 2NQ6A 1C21A 2BHCA 2GU4A 1QXWA 4PNCA 1WN1A 4FO8A 4IKSA 3PKBA 1KQ9A 4U6WA 4QR8A 1YW9A 1C27A 2GZ5A 2Q96A 4FLIA 4S01A 3D27A 2Q94A 4S00A 2Q95A 2MATA 2V6CA 4HXXA 5FCHA 3RVAA 1YW7A 2P98A 5CE6A 1C22A 4U1BA 4U76A 2BWUA 4EGEA 1WLRA 2IW2A 4U6ZA
chains in the Genus database with same CATH topology
3RORA 4U71A 1JAWA 3BITA 3BIPA 4B28A 2EVMA 4FKCA 4IKTA 2V3XA 3Q6DA 3MATA 3BIQA 4S2TP 2ZSGA 2V3ZA 4FLJA 2BHBA 3L7GA 4Z7MA 2EVCA 3IU8A 3MX6A 5JI6A 3CB5A 4PV4A 2GU6A 1MATA 4R60A 2BWVA 2GG3A 5JHUA 1O0XA 1QXYA 2Q92A 2OAZA 5CDVA 4IECA 1XGNA 2BHDA 4FUKA 1KQ0A 3CB6A 2Q93A 1M35A 2ADUA 2B3KA 1XGOA 1R5HA 3PKDA 2GU7A 5D6FA 1WL6A 2EVOA 4RZZA 1BOAA 4FO7A 1YJ3A 5JFRA 2GG8A 4FLKA 1B6AA 1XGMA 2OKNA 4U6CA 1R58A 4ZWPA 1C23A 3IU9A 1WL9A 4U70A 4IU6A 4U69A 4IPAA 2GG9A 1CHMA 2GG2A 5CIKA 2GTXA 5FCFA 3FM3A 4ZWOA 2GG0A 2P99A 5CDLA 3L24A 4A6WA 2HOWA 1Y1NA 4ZWUA 1XGSA 4IKRA 2EA4A 1R5GA 4MATA 4S2RP 4U73A 4JUQA 5E5BA 1QXZA 1KP0A 4IF7A 2G6PA 3TB5A 3MR1A 2BHAA 2NQ7A 3CTZA 2EA2A 1WKMA 2BB7A 2BWTA 2BH3A 1WBQA 3FMRA 1A16A 2GGCA 1XNZA 2P9AA 5D6EA 2GA2A 1W7VA 4U75A 1WY2A 3PKAA 2BWSA 1C24A 4ZNGA 2B3HA 4U6EA 1PV9A 3TAVA 4RZYA 2BWXA 5CLSA 2B3LA 4IKUA 2Q8KA 3FMQA 1N51A 1YW8A 3S6BA 5CDEA 3IU7A 1B59A 1YVMA 4RGZ1 2BWWA 3IG4A 1QZYA 1W2MA 3PKCA 2GG5A 2GG7A 1BN5A 4U6JA 2V3YA 4A6VA 2GU5A 2BWYA 2DFIA 4OOKA 3PKEA 5CNXA 2GGBA 4IDYA 4KM3A 2BN7A 4FLLA 2NQ6A 1C21A 2BHCA 2GU4A 1QXWA 4PNCA 1WN1A 4FO8A 4IKSA 3PKBA 1KQ9A 4U6WA 4QR8A 1YW9A 1C27A 2GZ5A 2Q96A 4FLIA 4S01A 3D27A 2Q94A 4S00A 2Q95A 2MATA 2V6CA 4HXXA 5FCHA 3RVAA 1YW7A 2P98A 5CE6A 1C22A 4U1BA 4U76A 2BWUA 4EGEA 1WLRA 2IW2A 4U6ZA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3ROR A;  4U71 A;  1JAW A;  3BIT A;  3BIP A;  4B28 A;  2EVM A;  4FKC A;  4IKT A;  2V3X A;  3Q6D A;  3MAT A;  3BIQ A;  4S2T P;  2ZSG A;  2V3Z A;  4FLJ A;  2BHB A;  3L7G A;  4Z7M A;  2EVC A;  3IU8 A;  3MX6 A;  5JI6 A;  3CB5 A;  4PV4 A;  2GU6 A;  1MAT A;  4R60 A;  2BWV A;  2GG3 A;  5JHU A;  1O0X A;  1QXY A;  2Q92 A;  2OAZ A;  5CDV A;  4IEC A;  1XGN A;  2BHD A;  4FUK A;  1KQ0 A;  3CB6 A;  2Q93 A;  1M35 A;  2ADU A;  2B3K A;  1XGO A;  1R5H A;  3PKD A;  2GU7 A;  5D6F A;  1WL6 A;  2EVO A;  4RZZ A;  1BOA A;  4FO7 A;  1YJ3 A;  5JFR A;  2GG8 A;  4FLK A;  1B6A A;  1XGM A;  2OKN A;  4U6C A;  1R58 A;  4ZWP A;  1C23 A;  3IU9 A;  1WL9 A;  4U70 A;  4IU6 A;  4U69 A;  4IPA A;  2GG9 A;  1CHM A;  2GG2 A;  5CIK A;  2GTX A;  5FCF A;  3FM3 A;  4ZWO A;  2GG0 A;  2P99 A;  5CDL A;  3L24 A;  4A6W A;  2HOW A;  1Y1N A;  4ZWU A;  1XGS A;  4IKR A;  2EA4 A;  1R5G A;  4MAT A;  4S2R P;  4U73 A;  4JUQ A;  5E5B A;  1QXZ A;  1KP0 A;  4IF7 A;  2G6P A;  3TB5 A;  3MR1 A;  2BHA A;  2NQ7 A;  3CTZ A;  2EA2 A;  1WKM A;  2BB7 A;  2BWT A;  2BH3 A;  1WBQ A;  3FMR A;  1A16 A;  2GGC A;  1XNZ A;  2P9A A;  5D6E A;  2GA2 A;  1W7V A;  4U75 A;  1WY2 A;  3PKA A;  2BWS A;  1C24 A;  4ZNG A;  2B3H A;  4U6E A;  1PV9 A;  3TAV A;  4RZY A;  2BWX A;  5CLS A;  2B3L A;  4IKU A;  2Q8K A;  3FMQ A;  1N51 A;  1YW8 A;  3S6B A;  5CDE A;  3IU7 A;  1B59 A;  1YVM A;  4RGZ 1;  2BWW A;  3IG4 A;  1QZY A;  1W2M A;  3PKC A;  2GG5 A;  2GG7 A;  1BN5 A;  4U6J A;  2V3Y A;  4A6V A;  2GU5 A;  2BWY A;  2DFI A;  4OOK A;  3PKE A;  5CNX A;  2GGB A;  4IDY A;  4KM3 A;  2BN7 A;  4FLL A;  2NQ6 A;  1C21 A;  2BHC A;  2GU4 A;  1QXW A;  4PNC A;  1WN1 A;  4FO8 A;  4IKS A;  3PKB A;  1KQ9 A;  4U6W A;  4QR8 A;  1YW9 A;  1C27 A;  2GZ5 A;  2Q96 A;  4FLI A;  4S01 A;  3D27 A;  2Q94 A;  4S00 A;  2Q95 A;  2MAT A;  2V6C A;  4HXX A;  5FCH A;  3RVA A;  1YW7 A;  2P98 A;  5CE6 A;  1C22 A;  4U1B A;  4U76 A;  2BWU A;  4EGE A;  1WLR A;  2IW2 A;  4U6Z A; 
#chains in the Genus database with same CATH topology
 3ROR A;  4U71 A;  1JAW A;  3BIT A;  3BIP A;  4B28 A;  2EVM A;  4FKC A;  4IKT A;  2V3X A;  3Q6D A;  3MAT A;  3BIQ A;  4S2T P;  2ZSG A;  2V3Z A;  4FLJ A;  2BHB A;  3L7G A;  4Z7M A;  2EVC A;  3IU8 A;  3MX6 A;  5JI6 A;  3CB5 A;  4PV4 A;  2GU6 A;  1MAT A;  4R60 A;  2BWV A;  2GG3 A;  5JHU A;  1O0X A;  1QXY A;  2Q92 A;  2OAZ A;  5CDV A;  4IEC A;  1XGN A;  2BHD A;  4FUK A;  1KQ0 A;  3CB6 A;  2Q93 A;  1M35 A;  2ADU A;  2B3K A;  1XGO A;  1R5H A;  3PKD A;  2GU7 A;  5D6F A;  1WL6 A;  2EVO A;  4RZZ A;  1BOA A;  4FO7 A;  1YJ3 A;  5JFR A;  2GG8 A;  4FLK A;  1B6A A;  1XGM A;  2OKN A;  4U6C A;  1R58 A;  4ZWP A;  1C23 A;  3IU9 A;  1WL9 A;  4U70 A;  4IU6 A;  4U69 A;  4IPA A;  2GG9 A;  1CHM A;  2GG2 A;  5CIK A;  2GTX A;  5FCF A;  3FM3 A;  4ZWO A;  2GG0 A;  2P99 A;  5CDL A;  3L24 A;  4A6W A;  2HOW A;  1Y1N A;  4ZWU A;  1XGS A;  4IKR A;  2EA4 A;  1R5G A;  4MAT A;  4S2R P;  4U73 A;  4JUQ A;  5E5B A;  1QXZ A;  1KP0 A;  4IF7 A;  2G6P A;  3TB5 A;  3MR1 A;  2BHA A;  2NQ7 A;  3CTZ A;  2EA2 A;  1WKM A;  2BB7 A;  2BWT A;  2BH3 A;  1WBQ A;  3FMR A;  1A16 A;  2GGC A;  1XNZ A;  2P9A A;  5D6E A;  2GA2 A;  1W7V A;  4U75 A;  1WY2 A;  3PKA A;  2BWS A;  1C24 A;  4ZNG A;  2B3H A;  4U6E A;  1PV9 A;  3TAV A;  4RZY A;  2BWX A;  5CLS A;  2B3L A;  4IKU A;  2Q8K A;  3FMQ A;  1N51 A;  1YW8 A;  3S6B A;  5CDE A;  3IU7 A;  1B59 A;  1YVM A;  4RGZ 1;  2BWW A;  3IG4 A;  1QZY A;  1W2M A;  3PKC A;  2GG5 A;  2GG7 A;  1BN5 A;  4U6J A;  2V3Y A;  4A6V A;  2GU5 A;  2BWY A;  2DFI A;  4OOK A;  3PKE A;  5CNX A;  2GGB A;  4IDY A;  4KM3 A;  2BN7 A;  4FLL A;  2NQ6 A;  1C21 A;  2BHC A;  2GU4 A;  1QXW A;  4PNC A;  1WN1 A;  4FO8 A;  4IKS A;  3PKB A;  1KQ9 A;  4U6W A;  4QR8 A;  1YW9 A;  1C27 A;  2GZ5 A;  2Q96 A;  4FLI A;  4S01 A;  3D27 A;  2Q94 A;  4S00 A;  2Q95 A;  2MAT A;  2V6C A;  4HXX A;  5FCH A;  3RVA A;  1YW7 A;  2P98 A;  5CE6 A;  1C22 A;  4U1B A;  4U76 A;  2BWU A;  4EGE A;  1WLR A;  2IW2 A;  4U6Z A; 
#chains in the Genus database with same CATH homology
 3ROR A;  4U71 A;  1JAW A;  3BIT A;  3BIP A;  4B28 A;  2EVM A;  4FKC A;  4IKT A;  2V3X A;  3Q6D A;  3MAT A;  3BIQ A;  4S2T P;  2ZSG A;  2V3Z A;  4FLJ A;  2BHB A;  3L7G A;  4Z7M A;  2EVC A;  3IU8 A;  3MX6 A;  5JI6 A;  3CB5 A;  4PV4 A;  2GU6 A;  1MAT A;  4R60 A;  2BWV A;  2GG3 A;  5JHU A;  1O0X A;  1QXY A;  2Q92 A;  2OAZ A;  5CDV A;  4IEC A;  1XGN A;  2BHD A;  4FUK A;  1KQ0 A;  3CB6 A;  2Q93 A;  1M35 A;  2ADU A;  2B3K A;  1XGO A;  1R5H A;  3PKD A;  2GU7 A;  5D6F A;  1WL6 A;  2EVO A;  4RZZ A;  1BOA A;  4FO7 A;  1YJ3 A;  5JFR A;  2GG8 A;  4FLK A;  1B6A A;  1XGM A;  2OKN A;  4U6C A;  1R58 A;  4ZWP A;  1C23 A;  3IU9 A;  1WL9 A;  4U70 A;  4IU6 A;  4U69 A;  4IPA A;  2GG9 A;  1CHM A;  2GG2 A;  5CIK A;  2GTX A;  5FCF A;  3FM3 A;  4ZWO A;  2GG0 A;  2P99 A;  5CDL A;  3L24 A;  4A6W A;  2HOW A;  1Y1N A;  4ZWU A;  1XGS A;  4IKR A;  2EA4 A;  1R5G A;  4MAT A;  4S2R P;  4U73 A;  4JUQ A;  5E5B A;  1QXZ A;  1KP0 A;  4IF7 A;  2G6P A;  3TB5 A;  3MR1 A;  2BHA A;  2NQ7 A;  3CTZ A;  2EA2 A;  1WKM A;  2BB7 A;  2BWT A;  2BH3 A;  1WBQ A;  3FMR A;  1A16 A;  2GGC A;  1XNZ A;  2P9A A;  5D6E A;  2GA2 A;  1W7V A;  4U75 A;  1WY2 A;  3PKA A;  2BWS A;  1C24 A;  4ZNG A;  2B3H A;  4U6E A;  1PV9 A;  3TAV A;  4RZY A;  2BWX A;  5CLS A;  2B3L A;  4IKU A;  2Q8K A;  3FMQ A;  1N51 A;  1YW8 A;  3S6B A;  5CDE A;  3IU7 A;  1B59 A;  1YVM A;  4RGZ 1;  2BWW A;  3IG4 A;  1QZY A;  1W2M A;  3PKC A;  2GG5 A;  2GG7 A;  1BN5 A;  4U6J A;  2V3Y A;  4A6V A;  2GU5 A;  2BWY A;  2DFI A;  4OOK A;  3PKE A;  5CNX A;  2GGB A;  4IDY A;  4KM3 A;  2BN7 A;  4FLL A;  2NQ6 A;  1C21 A;  2BHC A;  2GU4 A;  1QXW A;  4PNC A;  1WN1 A;  4FO8 A;  4IKS A;  3PKB A;  1KQ9 A;  4U6W A;  4QR8 A;  1YW9 A;  1C27 A;  2GZ5 A;  2Q96 A;  4FLI A;  4S01 A;  3D27 A;  2Q94 A;  4S00 A;  2Q95 A;  2MAT A;  2V6C A;  4HXX A;  5FCH A;  3RVA A;  1YW7 A;  2P98 A;  5CE6 A;  1C22 A;  4U1B A;  4U76 A;  2BWU A;  4EGE A;  1WLR A;  2IW2 A;  4U6Z A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite