4A6WA

X-ray structures of oxazole hydroxamate ecmetap-mn complexes
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transferase
molecule keywords METHIONINE AMINOPEPTIDASE
publication title Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
pubmed doi rcsb
total genus 83
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4a6wA00
2P9AA 2V6CA 3CB6A 4PNCA 1W7VA 3MR1A 4FUKA 1PV9A 4IF7A 2BB7A 4IKRA 3BIPA 2BH3A 2Q96A 4U6ZA 4MATA 3MX6A 4S01A 2P98A 2BN7A 2GZ5A 3IU8A 4FLJA 1XGOA 4FKCA 4PV4A 4FLKA 1M35A 4IDYA 1QXZA 4S00A 2BHCA 2B3KA 3Q6DA 4U6WA 2EA4A 5E5BA 2GU4A 3IU9A 3RVAA 1WKMA 2GG2A 1XGSA 2GU5A 3IG4A 4IKTA 4IU6A 4U6JA 5CDEA 4HXXA 4B28A 4FLLA 1CHMA 1YW8A 2ZSGA 1BOAA 2GA2A 3PKCA 3MATA 5CNXA 4Z7MA 2EVOA 2V3YA 2GG0A 4U69A 4RGZ1 2GG8A 2BWTA 4A6WA 1KP0A 1B6AA 3PKBA 1WY2A 2B3LA 2DFIA 4IECA 1Y1NA 4FO8A 2BWSA 4KM3A 1JAWA 2GTXA 2OKNA 5JHUA 4FLIA 4U6CA 1N51A 1KQ9A 2EA2A 4U73A 1WBQA 2GU6A 1R58A 2G6PA 4QR8A 2ADUA 1C22A 4U75A 5FCFA 5CDVA 4RZZA 3L7GA 2NQ7A 3IU7A 4U1BA 1C27A 2GGBA 2BHDA 4ZWPA 1WN1A 2MATA 4JUQA 5D6EA 3FMQA 4U71A 2Q95A 3S6BA 2NQ6A 1WL6A 4FO7A 4IKUA 2GG7A 3RORA 1O0XA 2BWWA 3CB5A 1R5HA 4ZNGA 5CDLA 4S2TP 3PKAA 2Q93A 1KQ0A 2BWXA 1YVMA 2OAZA 2GG3A 4S2RP 2GG9A 1MATA 3FMRA 2V3ZA 1WLRA 4RZYA 4ZWUA 3BITA 2BWVA 2B3HA 2EVCA 2BHAA 5JI6A 2Q8KA 4EGEA 3D27A 2IW2A 1W2MA 2HOWA 3PKDA 5FCHA 2BWYA 1WL9A 4OOKA 3FM3A 1C23A 3CTZA 1XGMA 2GGCA 1YW9A 4R60A 2GU7A 2Q92A 5D6FA 2BHBA 1C24A 4U70A 1YJ3A 1BN5A 1B59A 1QZYA 2BWUA 4IPAA 1XNZA 4U6EA 4ZWOA 4IKSA 2GG5A 2P99A 2EVMA 3PKEA 1QXYA 4A6VA 3BIQA 1A16A 3TB5A 1XGNA 1YW7A 5CIKA 5CE6A 3L24A 1C21A 4U76A 1R5GA 5JFRA 2V3XA 1QXWA 5CLSA 2Q94A 3TAVA
chains in the Genus database with same CATH superfamily
2P9AA 2V6CA 3CB6A 4PNCA 1W7VA 3MR1A 4FUKA 1PV9A 4IF7A 2BB7A 4IKRA 3BIPA 2BH3A 2Q96A 4U6ZA 4MATA 3MX6A 4S01A 2P98A 2BN7A 2GZ5A 3IU8A 4FLJA 1XGOA 4FKCA 4PV4A 4FLKA 1M35A 4IDYA 1QXZA 4S00A 2BHCA 2B3KA 3Q6DA 4U6WA 2EA4A 5E5BA 2GU4A 3IU9A 3RVAA 1WKMA 2GG2A 1XGSA 2GU5A 3IG4A 4IKTA 4IU6A 4U6JA 5CDEA 4HXXA 4B28A 4FLLA 1CHMA 1YW8A 2ZSGA 1BOAA 2GA2A 3PKCA 3MATA 5CNXA 4Z7MA 2EVOA 2V3YA 2GG0A 4U69A 4RGZ1 2GG8A 2BWTA 4A6WA 1KP0A 1B6AA 3PKBA 1WY2A 2B3LA 2DFIA 4IECA 1Y1NA 4FO8A 2BWSA 4KM3A 1JAWA 2GTXA 2OKNA 5JHUA 4FLIA 4U6CA 1N51A 1KQ9A 2EA2A 4U73A 1WBQA 2GU6A 1R58A 2G6PA 4QR8A 2ADUA 1C22A 4U75A 5FCFA 5CDVA 4RZZA 3L7GA 2NQ7A 3IU7A 4U1BA 1C27A 2GGBA 2BHDA 4ZWPA 1WN1A 2MATA 4JUQA 5D6EA 3FMQA 4U71A 2Q95A 3S6BA 2NQ6A 1WL6A 4FO7A 4IKUA 2GG7A 3RORA 1O0XA 2BWWA 3CB5A 1R5HA 4ZNGA 5CDLA 4S2TP 3PKAA 2Q93A 1KQ0A 2BWXA 1YVMA 2OAZA 2GG3A 4S2RP 2GG9A 1MATA 3FMRA 2V3ZA 1WLRA 4RZYA 4ZWUA 3BITA 2BWVA 2B3HA 2EVCA 2BHAA 5JI6A 2Q8KA 4EGEA 3D27A 2IW2A 1W2MA 2HOWA 3PKDA 5FCHA 2BWYA 1WL9A 4OOKA 3FM3A 1C23A 3CTZA 1XGMA 2GGCA 1YW9A 4R60A 2GU7A 2Q92A 5D6FA 2BHBA 1C24A 4U70A 1YJ3A 1BN5A 1B59A 1QZYA 2BWUA 4IPAA 1XNZA 4U6EA 4ZWOA 4IKSA 2GG5A 2P99A 2EVMA 3PKEA 1QXYA 4A6VA 3BIQA 1A16A 3TB5A 1XGNA 1YW7A 5CIKA 5CE6A 3L24A 1C21A 4U76A 1R5GA 5JFRA 2V3XA 1QXWA 5CLSA 2Q94A 3TAVA
chains in the Genus database with same CATH topology
2P9AA 2V6CA 3CB6A 4PNCA 1W7VA 3MR1A 4FUKA 1PV9A 4IF7A 2BB7A 4IKRA 3BIPA 2BH3A 2Q96A 4U6ZA 4MATA 3MX6A 4S01A 2P98A 2BN7A 2GZ5A 3IU8A 4FLJA 1XGOA 4FKCA 4PV4A 4FLKA 1M35A 4IDYA 1QXZA 4S00A 2BHCA 2B3KA 3Q6DA 4U6WA 2EA4A 5E5BA 2GU4A 3IU9A 3RVAA 1WKMA 2GG2A 1XGSA 2GU5A 3IG4A 4IKTA 4IU6A 4U6JA 5CDEA 4HXXA 4B28A 4FLLA 1CHMA 1YW8A 2ZSGA 1BOAA 2GA2A 3PKCA 3MATA 5CNXA 4Z7MA 2EVOA 2V3YA 2GG0A 4U69A 4RGZ1 2GG8A 2BWTA 4A6WA 1KP0A 1B6AA 3PKBA 1WY2A 2B3LA 2DFIA 4IECA 1Y1NA 4FO8A 2BWSA 4KM3A 1JAWA 2GTXA 2OKNA 5JHUA 4FLIA 4U6CA 1N51A 1KQ9A 2EA2A 4U73A 1WBQA 2GU6A 1R58A 2G6PA 4QR8A 2ADUA 1C22A 4U75A 5FCFA 5CDVA 4RZZA 3L7GA 2NQ7A 3IU7A 4U1BA 1C27A 2GGBA 2BHDA 4ZWPA 1WN1A 2MATA 4JUQA 5D6EA 3FMQA 4U71A 2Q95A 3S6BA 2NQ6A 1WL6A 4FO7A 4IKUA 2GG7A 3RORA 1O0XA 2BWWA 3CB5A 1R5HA 4ZNGA 5CDLA 4S2TP 3PKAA 2Q93A 1KQ0A 2BWXA 1YVMA 2OAZA 2GG3A 4S2RP 2GG9A 1MATA 3FMRA 2V3ZA 1WLRA 4RZYA 4ZWUA 3BITA 2BWVA 2B3HA 2EVCA 2BHAA 5JI6A 2Q8KA 4EGEA 3D27A 2IW2A 1W2MA 2HOWA 3PKDA 5FCHA 2BWYA 1WL9A 4OOKA 3FM3A 1C23A 3CTZA 1XGMA 2GGCA 1YW9A 4R60A 2GU7A 2Q92A 5D6FA 2BHBA 1C24A 4U70A 1YJ3A 1BN5A 1B59A 1QZYA 2BWUA 4IPAA 1XNZA 4U6EA 4ZWOA 4IKSA 2GG5A 2P99A 2EVMA 3PKEA 1QXYA 4A6VA 3BIQA 1A16A 3TB5A 1XGNA 1YW7A 5CIKA 5CE6A 3L24A 1C21A 4U76A 1R5GA 5JFRA 2V3XA 1QXWA 5CLSA 2Q94A 3TAVA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2P9A A;  2V6C A;  3CB6 A;  4PNC A;  1W7V A;  3MR1 A;  4FUK A;  1PV9 A;  4IF7 A;  2BB7 A;  4IKR A;  3BIP A;  2BH3 A;  2Q96 A;  4U6Z A;  4MAT A;  3MX6 A;  4S01 A;  2P98 A;  2BN7 A;  2GZ5 A;  3IU8 A;  4FLJ A;  1XGO A;  4FKC A;  4PV4 A;  4FLK A;  1M35 A;  4IDY A;  1QXZ A;  4S00 A;  2BHC A;  2B3K A;  3Q6D A;  4U6W A;  2EA4 A;  5E5B A;  2GU4 A;  3IU9 A;  3RVA A;  1WKM A;  2GG2 A;  1XGS A;  2GU5 A;  3IG4 A;  4IKT A;  4IU6 A;  4U6J A;  5CDE A;  4HXX A;  4B28 A;  4FLL A;  1CHM A;  1YW8 A;  2ZSG A;  1BOA A;  2GA2 A;  3PKC A;  3MAT A;  5CNX A;  4Z7M A;  2EVO A;  2V3Y A;  2GG0 A;  4U69 A;  4RGZ 1;  2GG8 A;  2BWT A;  4A6W A;  1KP0 A;  1B6A A;  3PKB A;  1WY2 A;  2B3L A;  2DFI A;  4IEC A;  1Y1N A;  4FO8 A;  2BWS A;  4KM3 A;  1JAW A;  2GTX A;  2OKN A;  5JHU A;  4FLI A;  4U6C A;  1N51 A;  1KQ9 A;  2EA2 A;  4U73 A;  1WBQ A;  2GU6 A;  1R58 A;  2G6P A;  4QR8 A;  2ADU A;  1C22 A;  4U75 A;  5FCF A;  5CDV A;  4RZZ A;  3L7G A;  2NQ7 A;  3IU7 A;  4U1B A;  1C27 A;  2GGB A;  2BHD A;  4ZWP A;  1WN1 A;  2MAT A;  4JUQ A;  5D6E A;  3FMQ A;  4U71 A;  2Q95 A;  3S6B A;  2NQ6 A;  1WL6 A;  4FO7 A;  4IKU A;  2GG7 A;  3ROR A;  1O0X A;  2BWW A;  3CB5 A;  1R5H A;  4ZNG A;  5CDL A;  4S2T P;  3PKA A;  2Q93 A;  1KQ0 A;  2BWX A;  1YVM A;  2OAZ A;  2GG3 A;  4S2R P;  2GG9 A;  1MAT A;  3FMR A;  2V3Z A;  1WLR A;  4RZY A;  4ZWU A;  3BIT A;  2BWV A;  2B3H A;  2EVC A;  2BHA A;  5JI6 A;  2Q8K A;  4EGE A;  3D27 A;  2IW2 A;  1W2M A;  2HOW A;  3PKD A;  5FCH A;  2BWY A;  1WL9 A;  4OOK A;  3FM3 A;  1C23 A;  3CTZ A;  1XGM A;  2GGC A;  1YW9 A;  4R60 A;  2GU7 A;  2Q92 A;  5D6F A;  2BHB A;  1C24 A;  4U70 A;  1YJ3 A;  1BN5 A;  1B59 A;  1QZY A;  2BWU A;  4IPA A;  1XNZ A;  4U6E A;  4ZWO A;  4IKS A;  2GG5 A;  2P99 A;  2EVM A;  3PKE A;  1QXY A;  4A6V A;  3BIQ A;  1A16 A;  3TB5 A;  1XGN A;  1YW7 A;  5CIK A;  5CE6 A;  3L24 A;  1C21 A;  4U76 A;  1R5G A;  5JFR A;  2V3X A;  1QXW A;  5CLS A;  2Q94 A;  3TAV A; 
#chains in the Genus database with same CATH topology
 2P9A A;  2V6C A;  3CB6 A;  4PNC A;  1W7V A;  3MR1 A;  4FUK A;  1PV9 A;  4IF7 A;  2BB7 A;  4IKR A;  3BIP A;  2BH3 A;  2Q96 A;  4U6Z A;  4MAT A;  3MX6 A;  4S01 A;  2P98 A;  2BN7 A;  2GZ5 A;  3IU8 A;  4FLJ A;  1XGO A;  4FKC A;  4PV4 A;  4FLK A;  1M35 A;  4IDY A;  1QXZ A;  4S00 A;  2BHC A;  2B3K A;  3Q6D A;  4U6W A;  2EA4 A;  5E5B A;  2GU4 A;  3IU9 A;  3RVA A;  1WKM A;  2GG2 A;  1XGS A;  2GU5 A;  3IG4 A;  4IKT A;  4IU6 A;  4U6J A;  5CDE A;  4HXX A;  4B28 A;  4FLL A;  1CHM A;  1YW8 A;  2ZSG A;  1BOA A;  2GA2 A;  3PKC A;  3MAT A;  5CNX A;  4Z7M A;  2EVO A;  2V3Y A;  2GG0 A;  4U69 A;  4RGZ 1;  2GG8 A;  2BWT A;  4A6W A;  1KP0 A;  1B6A A;  3PKB A;  1WY2 A;  2B3L A;  2DFI A;  4IEC A;  1Y1N A;  4FO8 A;  2BWS A;  4KM3 A;  1JAW A;  2GTX A;  2OKN A;  5JHU A;  4FLI A;  4U6C A;  1N51 A;  1KQ9 A;  2EA2 A;  4U73 A;  1WBQ A;  2GU6 A;  1R58 A;  2G6P A;  4QR8 A;  2ADU A;  1C22 A;  4U75 A;  5FCF A;  5CDV A;  4RZZ A;  3L7G A;  2NQ7 A;  3IU7 A;  4U1B A;  1C27 A;  2GGB A;  2BHD A;  4ZWP A;  1WN1 A;  2MAT A;  4JUQ A;  5D6E A;  3FMQ A;  4U71 A;  2Q95 A;  3S6B A;  2NQ6 A;  1WL6 A;  4FO7 A;  4IKU A;  2GG7 A;  3ROR A;  1O0X A;  2BWW A;  3CB5 A;  1R5H A;  4ZNG A;  5CDL A;  4S2T P;  3PKA A;  2Q93 A;  1KQ0 A;  2BWX A;  1YVM A;  2OAZ A;  2GG3 A;  4S2R P;  2GG9 A;  1MAT A;  3FMR A;  2V3Z A;  1WLR A;  4RZY A;  4ZWU A;  3BIT A;  2BWV A;  2B3H A;  2EVC A;  2BHA A;  5JI6 A;  2Q8K A;  4EGE A;  3D27 A;  2IW2 A;  1W2M A;  2HOW A;  3PKD A;  5FCH A;  2BWY A;  1WL9 A;  4OOK A;  3FM3 A;  1C23 A;  3CTZ A;  1XGM A;  2GGC A;  1YW9 A;  4R60 A;  2GU7 A;  2Q92 A;  5D6F A;  2BHB A;  1C24 A;  4U70 A;  1YJ3 A;  1BN5 A;  1B59 A;  1QZY A;  2BWU A;  4IPA A;  1XNZ A;  4U6E A;  4ZWO A;  4IKS A;  2GG5 A;  2P99 A;  2EVM A;  3PKE A;  1QXY A;  4A6V A;  3BIQ A;  1A16 A;  3TB5 A;  1XGN A;  1YW7 A;  5CIK A;  5CE6 A;  3L24 A;  1C21 A;  4U76 A;  1R5G A;  5JFR A;  2V3X A;  1QXW A;  5CLS A;  2Q94 A;  3TAV A; 
#chains in the Genus database with same CATH homology
 2P9A A;  2V6C A;  3CB6 A;  4PNC A;  1W7V A;  3MR1 A;  4FUK A;  1PV9 A;  4IF7 A;  2BB7 A;  4IKR A;  3BIP A;  2BH3 A;  2Q96 A;  4U6Z A;  4MAT A;  3MX6 A;  4S01 A;  2P98 A;  2BN7 A;  2GZ5 A;  3IU8 A;  4FLJ A;  1XGO A;  4FKC A;  4PV4 A;  4FLK A;  1M35 A;  4IDY A;  1QXZ A;  4S00 A;  2BHC A;  2B3K A;  3Q6D A;  4U6W A;  2EA4 A;  5E5B A;  2GU4 A;  3IU9 A;  3RVA A;  1WKM A;  2GG2 A;  1XGS A;  2GU5 A;  3IG4 A;  4IKT A;  4IU6 A;  4U6J A;  5CDE A;  4HXX A;  4B28 A;  4FLL A;  1CHM A;  1YW8 A;  2ZSG A;  1BOA A;  2GA2 A;  3PKC A;  3MAT A;  5CNX A;  4Z7M A;  2EVO A;  2V3Y A;  2GG0 A;  4U69 A;  4RGZ 1;  2GG8 A;  2BWT A;  4A6W A;  1KP0 A;  1B6A A;  3PKB A;  1WY2 A;  2B3L A;  2DFI A;  4IEC A;  1Y1N A;  4FO8 A;  2BWS A;  4KM3 A;  1JAW A;  2GTX A;  2OKN A;  5JHU A;  4FLI A;  4U6C A;  1N51 A;  1KQ9 A;  2EA2 A;  4U73 A;  1WBQ A;  2GU6 A;  1R58 A;  2G6P A;  4QR8 A;  2ADU A;  1C22 A;  4U75 A;  5FCF A;  5CDV A;  4RZZ A;  3L7G A;  2NQ7 A;  3IU7 A;  4U1B A;  1C27 A;  2GGB A;  2BHD A;  4ZWP A;  1WN1 A;  2MAT A;  4JUQ A;  5D6E A;  3FMQ A;  4U71 A;  2Q95 A;  3S6B A;  2NQ6 A;  1WL6 A;  4FO7 A;  4IKU A;  2GG7 A;  3ROR A;  1O0X A;  2BWW A;  3CB5 A;  1R5H A;  4ZNG A;  5CDL A;  4S2T P;  3PKA A;  2Q93 A;  1KQ0 A;  2BWX A;  1YVM A;  2OAZ A;  2GG3 A;  4S2R P;  2GG9 A;  1MAT A;  3FMR A;  2V3Z A;  1WLR A;  4RZY A;  4ZWU A;  3BIT A;  2BWV A;  2B3H A;  2EVC A;  2BHA A;  5JI6 A;  2Q8K A;  4EGE A;  3D27 A;  2IW2 A;  1W2M A;  2HOW A;  3PKD A;  5FCH A;  2BWY A;  1WL9 A;  4OOK A;  3FM3 A;  1C23 A;  3CTZ A;  1XGM A;  2GGC A;  1YW9 A;  4R60 A;  2GU7 A;  2Q92 A;  5D6F A;  2BHB A;  1C24 A;  4U70 A;  1YJ3 A;  1BN5 A;  1B59 A;  1QZY A;  2BWU A;  4IPA A;  1XNZ A;  4U6E A;  4ZWO A;  4IKS A;  2GG5 A;  2P99 A;  2EVM A;  3PKE A;  1QXY A;  4A6V A;  3BIQ A;  1A16 A;  3TB5 A;  1XGN A;  1YW7 A;  5CIK A;  5CE6 A;  3L24 A;  1C21 A;  4U76 A;  1R5G A;  5JFR A;  2V3X A;  1QXW A;  5CLS A;  2Q94 A;  3TAV A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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