4U69 | Genus

Total Genus 102

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	102
sequence length	304
structure length	304
Chain Sequence	YRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMS

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases pubmed doi rcsb
molecule keywords	Methionine aminopeptidase 1
total genus	102
structure length	304
sequence length	304
ec nomenclature	ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date	2014-07-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00557	Peptidase_M24	Metallopeptidase family M24

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.230.10	Alpha Beta	Alpha-Beta Complex	Creatine Amidinohydrolase	Creatinase/methionine aminopeptidase superfamily	4u69A00

2B3HA 4FLJA 4U6EA 2GG8A 4ZWUA 4KM3A 4U6ZA 4R60A 5CDLA 2BWTA 2GTXA 2GGCA 1WLRA 3PKAA 1XNZA 2EVOA 3BIPA 1R58A 1B6AA 3CB6A 3RVAA 1M35A 2BWUA 4FLKA 1QXYA 2GU7A 1QXZA 2BWWA 3IU7A 4U73A 4RZYA 4U75A 1YJ3A 2G6PA 2GG9A 3FM3A 4PV4A 4IU6A 2EVMA 2IW2A 1C23A 3FMQA 4FO8A 2V3YA 2BWSA 1B59A 2BH3A 4U1BA 1QXWA 2Q94A 1WN1A 4IKRA 4S01A 5CDVA 2EVCA 4ZWPA 1KQ9A 3CB5A 2GA2A 3PKCA 4S2TP 4B28A 2Q93A 1BN5A 2BN7A 3Q6DA 3BIQA 2BHAA 1R5HA 1R5GA 3FMRA 3RORA 1Y1NA 1O0XA 3L7GA 2NQ6A 1C27A 4EGEA 2DFIA 3PKBA 4A6VA 2BHCA 5CLSA 1WL9A 3CTZA 4PNCA 4RGZ1 4U6WA 2Q8KA 4IPAA 1XGMA 2V6CA 2HOWA 1N51A 4MATA 4Z7MA 4FLLA 4U70A 2GG0A 5CE6A 1BOAA 4FKCA 5D6FA 3TB5A 5JFRA 1C24A 1YVMA 2EA4A 1CHMA 2BB7A 3MATA 4IKUA 1YW8A 1XGNA 3MX6A 4A6WA 4FUKA 5JHUA 1XGOA 2GU4A 2EA2A 1WL6A 4ZNGA 2Q95A 3D27A 5CIKA 2BWYA 2B3LA 2NQ7A 2P98A 4IECA 1PV9A 2BWXA 1WBQA 4IKSA 4HXXA 5JI6A 2GU5A 4U6CA 1C22A 2GG5A 5FCFA 1A16A 2GU6A 2ZSGA 5E5BA 4OOKA 4S00A 5CNXA 4IF7A 4U76A 2P9AA 2GZ5A 3IU8A 3L24A 1KP0A 2BHBA 4S2RP 1YW7A 3BITA 4FLIA 1YW9A 3IG4A 4FO7A 3TAVA 1WKMA 2BHDA 3PKEA 2V3ZA 2B3KA 5FCHA 4IDYA 3PKDA 5D6EA 2P99A 1C21A 2GG7A 3IU9A 1WY2A 4U69A 2OKNA 1KQ0A 2GG2A 3MR1A 2GG3A 4JUQA 2Q96A 1JAWA 1QZYA 2OAZA 4QR8A 4U6JA 2GGBA 1W7VA 2ADUA 3S6BA 4U71A 4ZWOA 1W2MA 2MATA 2Q92A 4IKTA 1XGSA 2V3XA 2BWVA 5CDEA 1MATA 4RZZA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2B3H A;  4FLJ A;  4U6E A;  2GG8 A;  4ZWU A;  4KM3 A;  4U6Z A;  4R60 A;  5CDL A;  2BWT A;  2GTX A;  2GGC A;  1WLR A;  3PKA A;  1XNZ A;  2EVO A;  3BIP A;  1R58 A;  1B6A A;  3CB6 A;  3RVA A;  1M35 A;  2BWU A;  4FLK A;  1QXY A;  2GU7 A;  1QXZ A;  2BWW A;  3IU7 A;  4U73 A;  4RZY A;  4U75 A;  1YJ3 A;  2G6P A;  2GG9 A;  3FM3 A;  4PV4 A;  4IU6 A;  2EVM A;  2IW2 A;  1C23 A;  3FMQ A;  4FO8 A;  2V3Y A;  2BWS A;  1B59 A;  2BH3 A;  4U1B A;  1QXW A;  2Q94 A;  1WN1 A;  4IKR A;  4S01 A;  5CDV A;  2EVC A;  4ZWP A;  1KQ9 A;  3CB5 A;  2GA2 A;  3PKC A;  4S2T P;  4B28 A;  2Q93 A;  1BN5 A;  2BN7 A;  3Q6D A;  3BIQ A;  2BHA A;  1R5H A;  1R5G A;  3FMR A;  3ROR A;  1Y1N A;  1O0X A;  3L7G A;  2NQ6 A;  1C27 A;  4EGE A;  2DFI A;  3PKB A;  4A6V A;  2BHC A;  5CLS A;  1WL9 A;  3CTZ A;  4PNC A;  4RGZ 1;  4U6W A;  2Q8K A;  4IPA A;  1XGM A;  2V6C A;  2HOW A;  1N51 A;  4MAT A;  4Z7M A;  4FLL A;  4U70 A;  2GG0 A;  5CE6 A;  1BOA A;  4FKC A;  5D6F A;  3TB5 A;  5JFR A;  1C24 A;  1YVM A;  2EA4 A;  1CHM A;  2BB7 A;  3MAT A;  4IKU A;  1YW8 A;  1XGN A;  3MX6 A;  4A6W A;  4FUK A;  5JHU A;  1XGO A;  2GU4 A;  2EA2 A;  1WL6 A;  4ZNG A;  2Q95 A;  3D27 A;  5CIK A;  2BWY A;  2B3L A;  2NQ7 A;  2P98 A;  4IEC A;  1PV9 A;  2BWX A;  1WBQ A;  4IKS A;  4HXX A;  5JI6 A;  2GU5 A;  4U6C A;  1C22 A;  2GG5 A;  5FCF A;  1A16 A;  2GU6 A;  2ZSG A;  5E5B A;  4OOK A;  4S00 A;  5CNX A;  4IF7 A;  4U76 A;  2P9A A;  2GZ5 A;  3IU8 A;  3L24 A;  1KP0 A;  2BHB A;  4S2R P;  1YW7 A;  3BIT A;  4FLI A;  1YW9 A;  3IG4 A;  4FO7 A;  3TAV A;  1WKM A;  2BHD A;  3PKE A;  2V3Z A;  2B3K A;  5FCH A;  4IDY A;  3PKD A;  5D6E A;  2P99 A;  1C21 A;  2GG7 A;  3IU9 A;  1WY2 A;  4U69 A;  2OKN A;  1KQ0 A;  2GG2 A;  3MR1 A;  2GG3 A;  4JUQ A;  2Q96 A;  1JAW A;  1QZY A;  2OAZ A;  4QR8 A;  4U6J A;  2GGB A;  1W7V A;  2ADU A;  3S6B A;  4U71 A;  4ZWO A;  1W2M A;  2MAT A;  2Q92 A;  4IKT A;  1XGS A;  2V3X A;  2BWV A;  5CDE A;  1MAT A;  4RZZ A; 
#chains in the Genus database with same CATH topology
 2B3H A;  4FLJ A;  4U6E A;  2GG8 A;  4ZWU A;  4KM3 A;  4U6Z A;  4R60 A;  5CDL A;  2BWT A;  2GTX A;  2GGC A;  1WLR A;  3PKA A;  1XNZ A;  2EVO A;  3BIP A;  1R58 A;  1B6A A;  3CB6 A;  3RVA A;  1M35 A;  2BWU A;  4FLK A;  1QXY A;  2GU7 A;  1QXZ A;  2BWW A;  3IU7 A;  4U73 A;  4RZY A;  4U75 A;  1YJ3 A;  2G6P A;  2GG9 A;  3FM3 A;  4PV4 A;  4IU6 A;  2EVM A;  2IW2 A;  1C23 A;  3FMQ A;  4FO8 A;  2V3Y A;  2BWS A;  1B59 A;  2BH3 A;  4U1B A;  1QXW A;  2Q94 A;  1WN1 A;  4IKR A;  4S01 A;  5CDV A;  2EVC A;  4ZWP A;  1KQ9 A;  3CB5 A;  2GA2 A;  3PKC A;  4S2T P;  4B28 A;  2Q93 A;  1BN5 A;  2BN7 A;  3Q6D A;  3BIQ A;  2BHA A;  1R5H A;  1R5G A;  3FMR A;  3ROR A;  1Y1N A;  1O0X A;  3L7G A;  2NQ6 A;  1C27 A;  4EGE A;  2DFI A;  3PKB A;  4A6V A;  2BHC A;  5CLS A;  1WL9 A;  3CTZ A;  4PNC A;  4RGZ 1;  4U6W A;  2Q8K A;  4IPA A;  1XGM A;  2V6C A;  2HOW A;  1N51 A;  4MAT A;  4Z7M A;  4FLL A;  4U70 A;  2GG0 A;  5CE6 A;  1BOA A;  4FKC A;  5D6F A;  3TB5 A;  5JFR A;  1C24 A;  1YVM A;  2EA4 A;  1CHM A;  2BB7 A;  3MAT A;  4IKU A;  1YW8 A;  1XGN A;  3MX6 A;  4A6W A;  4FUK A;  5JHU A;  1XGO A;  2GU4 A;  2EA2 A;  1WL6 A;  4ZNG A;  2Q95 A;  3D27 A;  5CIK A;  2BWY A;  2B3L A;  2NQ7 A;  2P98 A;  4IEC A;  1PV9 A;  2BWX A;  1WBQ A;  4IKS A;  4HXX A;  5JI6 A;  2GU5 A;  4U6C A;  1C22 A;  2GG5 A;  5FCF A;  1A16 A;  2GU6 A;  2ZSG A;  5E5B A;  4OOK A;  4S00 A;  5CNX A;  4IF7 A;  4U76 A;  2P9A A;  2GZ5 A;  3IU8 A;  3L24 A;  1KP0 A;  2BHB A;  4S2R P;  1YW7 A;  3BIT A;  4FLI A;  1YW9 A;  3IG4 A;  4FO7 A;  3TAV A;  1WKM A;  2BHD A;  3PKE A;  2V3Z A;  2B3K A;  5FCH A;  4IDY A;  3PKD A;  5D6E A;  2P99 A;  1C21 A;  2GG7 A;  3IU9 A;  1WY2 A;  4U69 A;  2OKN A;  1KQ0 A;  2GG2 A;  3MR1 A;  2GG3 A;  4JUQ A;  2Q96 A;  1JAW A;  1QZY A;  2OAZ A;  4QR8 A;  4U6J A;  2GGB A;  1W7V A;  2ADU A;  3S6B A;  4U71 A;  4ZWO A;  1W2M A;  2MAT A;  2Q92 A;  4IKT A;  1XGS A;  2V3X A;  2BWV A;  5CDE A;  1MAT A;  4RZZ A; 
#chains in the Genus database with same CATH homology
 2B3H A;  4FLJ A;  4U6E A;  2GG8 A;  4ZWU A;  4KM3 A;  4U6Z A;  4R60 A;  5CDL A;  2BWT A;  2GTX A;  2GGC A;  1WLR A;  3PKA A;  1XNZ A;  2EVO A;  3BIP A;  1R58 A;  1B6A A;  3CB6 A;  3RVA A;  1M35 A;  2BWU A;  4FLK A;  1QXY A;  2GU7 A;  1QXZ A;  2BWW A;  3IU7 A;  4U73 A;  4RZY A;  4U75 A;  1YJ3 A;  2G6P A;  2GG9 A;  3FM3 A;  4PV4 A;  4IU6 A;  2EVM A;  2IW2 A;  1C23 A;  3FMQ A;  4FO8 A;  2V3Y A;  2BWS A;  1B59 A;  2BH3 A;  4U1B A;  1QXW A;  2Q94 A;  1WN1 A;  4IKR A;  4S01 A;  5CDV A;  2EVC A;  4ZWP A;  1KQ9 A;  3CB5 A;  2GA2 A;  3PKC A;  4S2T P;  4B28 A;  2Q93 A;  1BN5 A;  2BN7 A;  3Q6D A;  3BIQ A;  2BHA A;  1R5H A;  1R5G A;  3FMR A;  3ROR A;  1Y1N A;  1O0X A;  3L7G A;  2NQ6 A;  1C27 A;  4EGE A;  2DFI A;  3PKB A;  4A6V A;  2BHC A;  5CLS A;  1WL9 A;  3CTZ A;  4PNC A;  4RGZ 1;  4U6W A;  2Q8K A;  4IPA A;  1XGM A;  2V6C A;  2HOW A;  1N51 A;  4MAT A;  4Z7M A;  4FLL A;  4U70 A;  2GG0 A;  5CE6 A;  1BOA A;  4FKC A;  5D6F A;  3TB5 A;  5JFR A;  1C24 A;  1YVM A;  2EA4 A;  1CHM A;  2BB7 A;  3MAT A;  4IKU A;  1YW8 A;  1XGN A;  3MX6 A;  4A6W A;  4FUK A;  5JHU A;  1XGO A;  2GU4 A;  2EA2 A;  1WL6 A;  4ZNG A;  2Q95 A;  3D27 A;  5CIK A;  2BWY A;  2B3L A;  2NQ7 A;  2P98 A;  4IEC A;  1PV9 A;  2BWX A;  1WBQ A;  4IKS A;  4HXX A;  5JI6 A;  2GU5 A;  4U6C A;  1C22 A;  2GG5 A;  5FCF A;  1A16 A;  2GU6 A;  2ZSG A;  5E5B A;  4OOK A;  4S00 A;  5CNX A;  4IF7 A;  4U76 A;  2P9A A;  2GZ5 A;  3IU8 A;  3L24 A;  1KP0 A;  2BHB A;  4S2R P;  1YW7 A;  3BIT A;  4FLI A;  1YW9 A;  3IG4 A;  4FO7 A;  3TAV A;  1WKM A;  2BHD A;  3PKE A;  2V3Z A;  2B3K A;  5FCH A;  4IDY A;  3PKD A;  5D6E A;  2P99 A;  1C21 A;  2GG7 A;  3IU9 A;  1WY2 A;  4U69 A;  2OKN A;  1KQ0 A;  2GG2 A;  3MR1 A;  2GG3 A;  4JUQ A;  2Q96 A;  1JAW A;  1QZY A;  2OAZ A;  4QR8 A;  4U6J A;  2GGB A;  1W7V A;  2ADU A;  3S6B A;  4U71 A;  4ZWO A;  1W2M A;  2MAT A;  2Q92 A;  4IKT A;  1XGS A;  2V3X A;  2BWV A;  5CDE A;  1MAT A;  4RZZ A;

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similar chains in the Genus database (?% sequence similarity)

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4U69A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations