4U6ZA

Hsmetap(f309m) in complex with 1-amino-2-propylpentyl)phosphonic acid
Total Genus 100

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
304
structure length
304
Chain Sequence
YRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLMHTAPNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTRRLDSARPHFMS
5010015020025030030025020015010050
020406080100Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTIV1 (116-119)TI2 (115-118)TI3 (117-120)TII5 (273-276)AH4 (252-271)AH1 (126-131)TII1 (131-134)S8 (276-277)AH2 (142-164)AH5 (279-291)TII2 (167-170)S1 (170-171)S3 (203-206)3H1 (195-197)AH3 (172-186)S7 (237-247)TI5 (190-193)S2 (189-190)TIV2 (233-236)S6 (224-234)TII3 (192-195)TII'1 (206-209)S4 (209-211)S5 (219-220)TII4 (221-224)S9 (295-296)TI6 (297-300)S10 (302-304)TI4 (120-123)TI1 (109-112)Updating...
connected with : NaN
molecule tags Hydrolase
source organism Homo sapiens
publication title Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases
pubmed doi rcsb
molecule keywords Methionine aminopeptidase 1
total genus 100
structure length 304
sequence length 304
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2014-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4u6zA00
4S2RP 4IKTA 4U6JA 1WL9A 1BN5A 2BWUA 2V3ZA 3FM3A 1QXZA 4FLLA 4RZYA 2ZSGA 2GG8A 2NQ6A 2BWYA 1QXYA 1O0XA 3Q6DA 1YJ3A 3RVAA 4ZNGA 3CTZA 1B59A 2B3HA 4U76A 2BHCA 4IPAA 2BWTA 2ADUA 2BHAA 2B3LA 3MATA 1MATA 2GGBA 1M35A 2BWWA 4FO8A 2GGCA 1PV9A 3FMRA 4S01A 5JHUA 4U6WA 4S00A 1YW7A 2EA4A 4A6VA 3TB5A 2HOWA 2Q92A 2P99A 3PKEA 1QZYA 2OKNA 3S6BA 2EVMA 2IW2A 1XGNA 1Y1NA 3IG4A 2BN7A 5CLSA 4PNCA 4OOKA 2GG5A 4IU6A 2GU4A 2OAZA 3D27A 5D6EA 1BOAA 3MR1A 3BIPA 2Q96A 3CB6A 4A6WA 1C21A 5FCHA 3L24A 4U73A 4EGEA 4QR8A 3FMQA 3CB5A 3IU8A 4RZZA 2GG0A 2NQ7A 1JAWA 4MATA 1WBQA 4PV4A 1YW8A 1KQ0A 4U6CA 1KQ9A 2DFIA 2V6CA 1C22A 2BWVA 1WN1A 2B3KA 1WLRA 4JUQA 4RGZ1 2BHBA 3IU9A 1WKMA 4R60A 1XGOA 5CNXA 3RORA 4IKSA 2Q94A 1W7VA 2EVOA 4IF7A 2GU6A 1N51A 2GZ5A 4FUKA 4IKRA 5CIKA 1KP0A 2GG9A 4FLKA 5CDLA 5CE6A 2GTXA 4ZWOA 4FKCA 5E5BA 4IECA 4U69A 2BH3A 1WL6A 3PKAA 4HXXA 2V3YA 1R5GA 2V3XA 4U6EA 2EVCA 3PKDA 1WY2A 1W2MA 1C27A 1B6AA 4U75A 2G6PA 5JFRA 4IKUA 4U6ZA 4KM3A 1A16A 5D6FA 1XGMA 1XNZA 1C23A 4IDYA 3BITA 4FLIA 4U71A 4Z7MA 1YW9A 2GU5A 4U1BA 4ZWUA 4FLJA 2Q8KA 2BHDA 3IU7A 2GG7A 4FO7A 2MATA 5CDVA 4U70A 2Q95A 3MX6A 2BWXA 2GU7A 3L7GA 1R58A 1XGSA 1C24A 1QXWA 2EA2A 2GG3A 5CDEA 2P9AA 3TAVA 3BIQA 2BWSA 3PKCA 2GA2A 1YVMA 4B28A 1R5HA 3PKBA 4S2TP 5FCFA 2Q93A 5JI6A 2GG2A 1CHMA 2P98A 2BB7A 4ZWPA
chains in the Genus database with same CATH superfamily
4S2RP 4IKTA 4U6JA 1WL9A 1BN5A 2BWUA 2V3ZA 3FM3A 1QXZA 4FLLA 4RZYA 2ZSGA 2GG8A 2NQ6A 2BWYA 1QXYA 1O0XA 3Q6DA 1YJ3A 3RVAA 4ZNGA 3CTZA 1B59A 2B3HA 4U76A 2BHCA 4IPAA 2BWTA 2ADUA 2BHAA 2B3LA 3MATA 1MATA 2GGBA 1M35A 2BWWA 4FO8A 2GGCA 1PV9A 3FMRA 4S01A 5JHUA 4U6WA 4S00A 1YW7A 2EA4A 4A6VA 3TB5A 2HOWA 2Q92A 2P99A 3PKEA 1QZYA 2OKNA 3S6BA 2EVMA 2IW2A 1XGNA 1Y1NA 3IG4A 2BN7A 5CLSA 4PNCA 4OOKA 2GG5A 4IU6A 2GU4A 2OAZA 3D27A 5D6EA 1BOAA 3MR1A 3BIPA 2Q96A 3CB6A 4A6WA 1C21A 5FCHA 3L24A 4U73A 4EGEA 4QR8A 3FMQA 3CB5A 3IU8A 4RZZA 2GG0A 2NQ7A 1JAWA 4MATA 1WBQA 4PV4A 1YW8A 1KQ0A 4U6CA 1KQ9A 2DFIA 2V6CA 1C22A 2BWVA 1WN1A 2B3KA 1WLRA 4JUQA 4RGZ1 2BHBA 3IU9A 1WKMA 4R60A 1XGOA 5CNXA 3RORA 4IKSA 2Q94A 1W7VA 2EVOA 4IF7A 2GU6A 1N51A 2GZ5A 4FUKA 4IKRA 5CIKA 1KP0A 2GG9A 4FLKA 5CDLA 5CE6A 2GTXA 4ZWOA 4FKCA 5E5BA 4IECA 4U69A 2BH3A 1WL6A 3PKAA 4HXXA 2V3YA 1R5GA 2V3XA 4U6EA 2EVCA 3PKDA 1WY2A 1W2MA 1C27A 1B6AA 4U75A 2G6PA 5JFRA 4IKUA 4U6ZA 4KM3A 1A16A 5D6FA 1XGMA 1XNZA 1C23A 4IDYA 3BITA 4FLIA 4U71A 4Z7MA 1YW9A 2GU5A 4U1BA 4ZWUA 4FLJA 2Q8KA 2BHDA 3IU7A 2GG7A 4FO7A 2MATA 5CDVA 4U70A 2Q95A 3MX6A 2BWXA 2GU7A 3L7GA 1R58A 1XGSA 1C24A 1QXWA 2EA2A 2GG3A 5CDEA 2P9AA 3TAVA 3BIQA 2BWSA 3PKCA 2GA2A 1YVMA 4B28A 1R5HA 3PKBA 4S2TP 5FCFA 2Q93A 5JI6A 2GG2A 1CHMA 2P98A 2BB7A 4ZWPA
chains in the Genus database with same CATH topology
4S2RP 4IKTA 4U6JA 1WL9A 1BN5A 2BWUA 2V3ZA 3FM3A 1QXZA 4FLLA 4RZYA 2ZSGA 2GG8A 2NQ6A 2BWYA 1QXYA 1O0XA 3Q6DA 1YJ3A 3RVAA 4ZNGA 3CTZA 1B59A 2B3HA 4U76A 2BHCA 4IPAA 2BWTA 2ADUA 2BHAA 2B3LA 3MATA 1MATA 2GGBA 1M35A 2BWWA 4FO8A 2GGCA 1PV9A 3FMRA 4S01A 5JHUA 4U6WA 4S00A 1YW7A 2EA4A 4A6VA 3TB5A 2HOWA 2Q92A 2P99A 3PKEA 1QZYA 2OKNA 3S6BA 2EVMA 2IW2A 1XGNA 1Y1NA 3IG4A 2BN7A 5CLSA 4PNCA 4OOKA 2GG5A 4IU6A 2GU4A 2OAZA 3D27A 5D6EA 1BOAA 3MR1A 3BIPA 2Q96A 3CB6A 4A6WA 1C21A 5FCHA 3L24A 4U73A 4EGEA 4QR8A 3FMQA 3CB5A 3IU8A 4RZZA 2GG0A 2NQ7A 1JAWA 4MATA 1WBQA 4PV4A 1YW8A 1KQ0A 4U6CA 1KQ9A 2DFIA 2V6CA 1C22A 2BWVA 1WN1A 2B3KA 1WLRA 4JUQA 4RGZ1 2BHBA 3IU9A 1WKMA 4R60A 1XGOA 5CNXA 3RORA 4IKSA 2Q94A 1W7VA 2EVOA 4IF7A 2GU6A 1N51A 2GZ5A 4FUKA 4IKRA 5CIKA 1KP0A 2GG9A 4FLKA 5CDLA 5CE6A 2GTXA 4ZWOA 4FKCA 5E5BA 4IECA 4U69A 2BH3A 1WL6A 3PKAA 4HXXA 2V3YA 1R5GA 2V3XA 4U6EA 2EVCA 3PKDA 1WY2A 1W2MA 1C27A 1B6AA 4U75A 2G6PA 5JFRA 4IKUA 4U6ZA 4KM3A 1A16A 5D6FA 1XGMA 1XNZA 1C23A 4IDYA 3BITA 4FLIA 4U71A 4Z7MA 1YW9A 2GU5A 4U1BA 4ZWUA 4FLJA 2Q8KA 2BHDA 3IU7A 2GG7A 4FO7A 2MATA 5CDVA 4U70A 2Q95A 3MX6A 2BWXA 2GU7A 3L7GA 1R58A 1XGSA 1C24A 1QXWA 2EA2A 2GG3A 5CDEA 2P9AA 3TAVA 3BIQA 2BWSA 3PKCA 2GA2A 1YVMA 4B28A 1R5HA 3PKBA 4S2TP 5FCFA 2Q93A 5JI6A 2GG2A 1CHMA 2P98A 2BB7A 4ZWPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4S2R P;  4IKT A;  4U6J A;  1WL9 A;  1BN5 A;  2BWU A;  2V3Z A;  3FM3 A;  1QXZ A;  4FLL A;  4RZY A;  2ZSG A;  2GG8 A;  2NQ6 A;  2BWY A;  1QXY A;  1O0X A;  3Q6D A;  1YJ3 A;  3RVA A;  4ZNG A;  3CTZ A;  1B59 A;  2B3H A;  4U76 A;  2BHC A;  4IPA A;  2BWT A;  2ADU A;  2BHA A;  2B3L A;  3MAT A;  1MAT A;  2GGB A;  1M35 A;  2BWW A;  4FO8 A;  2GGC A;  1PV9 A;  3FMR A;  4S01 A;  5JHU A;  4U6W A;  4S00 A;  1YW7 A;  2EA4 A;  4A6V A;  3TB5 A;  2HOW A;  2Q92 A;  2P99 A;  3PKE A;  1QZY A;  2OKN A;  3S6B A;  2EVM A;  2IW2 A;  1XGN A;  1Y1N A;  3IG4 A;  2BN7 A;  5CLS A;  4PNC A;  4OOK A;  2GG5 A;  4IU6 A;  2GU4 A;  2OAZ A;  3D27 A;  5D6E A;  1BOA A;  3MR1 A;  3BIP A;  2Q96 A;  3CB6 A;  4A6W A;  1C21 A;  5FCH A;  3L24 A;  4U73 A;  4EGE A;  4QR8 A;  3FMQ A;  3CB5 A;  3IU8 A;  4RZZ A;  2GG0 A;  2NQ7 A;  1JAW A;  4MAT A;  1WBQ A;  4PV4 A;  1YW8 A;  1KQ0 A;  4U6C A;  1KQ9 A;  2DFI A;  2V6C A;  1C22 A;  2BWV A;  1WN1 A;  2B3K A;  1WLR A;  4JUQ A;  4RGZ 1;  2BHB A;  3IU9 A;  1WKM A;  4R60 A;  1XGO A;  5CNX A;  3ROR A;  4IKS A;  2Q94 A;  1W7V A;  2EVO A;  4IF7 A;  2GU6 A;  1N51 A;  2GZ5 A;  4FUK A;  4IKR A;  5CIK A;  1KP0 A;  2GG9 A;  4FLK A;  5CDL A;  5CE6 A;  2GTX A;  4ZWO A;  4FKC A;  5E5B A;  4IEC A;  4U69 A;  2BH3 A;  1WL6 A;  3PKA A;  4HXX A;  2V3Y A;  1R5G A;  2V3X A;  4U6E A;  2EVC A;  3PKD A;  1WY2 A;  1W2M A;  1C27 A;  1B6A A;  4U75 A;  2G6P A;  5JFR A;  4IKU A;  4U6Z A;  4KM3 A;  1A16 A;  5D6F A;  1XGM A;  1XNZ A;  1C23 A;  4IDY A;  3BIT A;  4FLI A;  4U71 A;  4Z7M A;  1YW9 A;  2GU5 A;  4U1B A;  4ZWU A;  4FLJ A;  2Q8K A;  2BHD A;  3IU7 A;  2GG7 A;  4FO7 A;  2MAT A;  5CDV A;  4U70 A;  2Q95 A;  3MX6 A;  2BWX A;  2GU7 A;  3L7G A;  1R58 A;  1XGS A;  1C24 A;  1QXW A;  2EA2 A;  2GG3 A;  5CDE A;  2P9A A;  3TAV A;  3BIQ A;  2BWS A;  3PKC A;  2GA2 A;  1YVM A;  4B28 A;  1R5H A;  3PKB A;  4S2T P;  5FCF A;  2Q93 A;  5JI6 A;  2GG2 A;  1CHM A;  2P98 A;  2BB7 A;  4ZWP A; 
#chains in the Genus database with same CATH topology
 4S2R P;  4IKT A;  4U6J A;  1WL9 A;  1BN5 A;  2BWU A;  2V3Z A;  3FM3 A;  1QXZ A;  4FLL A;  4RZY A;  2ZSG A;  2GG8 A;  2NQ6 A;  2BWY A;  1QXY A;  1O0X A;  3Q6D A;  1YJ3 A;  3RVA A;  4ZNG A;  3CTZ A;  1B59 A;  2B3H A;  4U76 A;  2BHC A;  4IPA A;  2BWT A;  2ADU A;  2BHA A;  2B3L A;  3MAT A;  1MAT A;  2GGB A;  1M35 A;  2BWW A;  4FO8 A;  2GGC A;  1PV9 A;  3FMR A;  4S01 A;  5JHU A;  4U6W A;  4S00 A;  1YW7 A;  2EA4 A;  4A6V A;  3TB5 A;  2HOW A;  2Q92 A;  2P99 A;  3PKE A;  1QZY A;  2OKN A;  3S6B A;  2EVM A;  2IW2 A;  1XGN A;  1Y1N A;  3IG4 A;  2BN7 A;  5CLS A;  4PNC A;  4OOK A;  2GG5 A;  4IU6 A;  2GU4 A;  2OAZ A;  3D27 A;  5D6E A;  1BOA A;  3MR1 A;  3BIP A;  2Q96 A;  3CB6 A;  4A6W A;  1C21 A;  5FCH A;  3L24 A;  4U73 A;  4EGE A;  4QR8 A;  3FMQ A;  3CB5 A;  3IU8 A;  4RZZ A;  2GG0 A;  2NQ7 A;  1JAW A;  4MAT A;  1WBQ A;  4PV4 A;  1YW8 A;  1KQ0 A;  4U6C A;  1KQ9 A;  2DFI A;  2V6C A;  1C22 A;  2BWV A;  1WN1 A;  2B3K A;  1WLR A;  4JUQ A;  4RGZ 1;  2BHB A;  3IU9 A;  1WKM A;  4R60 A;  1XGO A;  5CNX A;  3ROR A;  4IKS A;  2Q94 A;  1W7V A;  2EVO A;  4IF7 A;  2GU6 A;  1N51 A;  2GZ5 A;  4FUK A;  4IKR A;  5CIK A;  1KP0 A;  2GG9 A;  4FLK A;  5CDL A;  5CE6 A;  2GTX A;  4ZWO A;  4FKC A;  5E5B A;  4IEC A;  4U69 A;  2BH3 A;  1WL6 A;  3PKA A;  4HXX A;  2V3Y A;  1R5G A;  2V3X A;  4U6E A;  2EVC A;  3PKD A;  1WY2 A;  1W2M A;  1C27 A;  1B6A A;  4U75 A;  2G6P A;  5JFR A;  4IKU A;  4U6Z A;  4KM3 A;  1A16 A;  5D6F A;  1XGM A;  1XNZ A;  1C23 A;  4IDY A;  3BIT A;  4FLI A;  4U71 A;  4Z7M A;  1YW9 A;  2GU5 A;  4U1B A;  4ZWU A;  4FLJ A;  2Q8K A;  2BHD A;  3IU7 A;  2GG7 A;  4FO7 A;  2MAT A;  5CDV A;  4U70 A;  2Q95 A;  3MX6 A;  2BWX A;  2GU7 A;  3L7G A;  1R58 A;  1XGS A;  1C24 A;  1QXW A;  2EA2 A;  2GG3 A;  5CDE A;  2P9A A;  3TAV A;  3BIQ A;  2BWS A;  3PKC A;  2GA2 A;  1YVM A;  4B28 A;  1R5H A;  3PKB A;  4S2T P;  5FCF A;  2Q93 A;  5JI6 A;  2GG2 A;  1CHM A;  2P98 A;  2BB7 A;  4ZWP A; 
#chains in the Genus database with same CATH homology
 4S2R P;  4IKT A;  4U6J A;  1WL9 A;  1BN5 A;  2BWU A;  2V3Z A;  3FM3 A;  1QXZ A;  4FLL A;  4RZY A;  2ZSG A;  2GG8 A;  2NQ6 A;  2BWY A;  1QXY A;  1O0X A;  3Q6D A;  1YJ3 A;  3RVA A;  4ZNG A;  3CTZ A;  1B59 A;  2B3H A;  4U76 A;  2BHC A;  4IPA A;  2BWT A;  2ADU A;  2BHA A;  2B3L A;  3MAT A;  1MAT A;  2GGB A;  1M35 A;  2BWW A;  4FO8 A;  2GGC A;  1PV9 A;  3FMR A;  4S01 A;  5JHU A;  4U6W A;  4S00 A;  1YW7 A;  2EA4 A;  4A6V A;  3TB5 A;  2HOW A;  2Q92 A;  2P99 A;  3PKE A;  1QZY A;  2OKN A;  3S6B A;  2EVM A;  2IW2 A;  1XGN A;  1Y1N A;  3IG4 A;  2BN7 A;  5CLS A;  4PNC A;  4OOK A;  2GG5 A;  4IU6 A;  2GU4 A;  2OAZ A;  3D27 A;  5D6E A;  1BOA A;  3MR1 A;  3BIP A;  2Q96 A;  3CB6 A;  4A6W A;  1C21 A;  5FCH A;  3L24 A;  4U73 A;  4EGE A;  4QR8 A;  3FMQ A;  3CB5 A;  3IU8 A;  4RZZ A;  2GG0 A;  2NQ7 A;  1JAW A;  4MAT A;  1WBQ A;  4PV4 A;  1YW8 A;  1KQ0 A;  4U6C A;  1KQ9 A;  2DFI A;  2V6C A;  1C22 A;  2BWV A;  1WN1 A;  2B3K A;  1WLR A;  4JUQ A;  4RGZ 1;  2BHB A;  3IU9 A;  1WKM A;  4R60 A;  1XGO A;  5CNX A;  3ROR A;  4IKS A;  2Q94 A;  1W7V A;  2EVO A;  4IF7 A;  2GU6 A;  1N51 A;  2GZ5 A;  4FUK A;  4IKR A;  5CIK A;  1KP0 A;  2GG9 A;  4FLK A;  5CDL A;  5CE6 A;  2GTX A;  4ZWO A;  4FKC A;  5E5B A;  4IEC A;  4U69 A;  2BH3 A;  1WL6 A;  3PKA A;  4HXX A;  2V3Y A;  1R5G A;  2V3X A;  4U6E A;  2EVC A;  3PKD A;  1WY2 A;  1W2M A;  1C27 A;  1B6A A;  4U75 A;  2G6P A;  5JFR A;  4IKU A;  4U6Z A;  4KM3 A;  1A16 A;  5D6F A;  1XGM A;  1XNZ A;  1C23 A;  4IDY A;  3BIT A;  4FLI A;  4U71 A;  4Z7M A;  1YW9 A;  2GU5 A;  4U1B A;  4ZWU A;  4FLJ A;  2Q8K A;  2BHD A;  3IU7 A;  2GG7 A;  4FO7 A;  2MAT A;  5CDV A;  4U70 A;  2Q95 A;  3MX6 A;  2BWX A;  2GU7 A;  3L7G A;  1R58 A;  1XGS A;  1C24 A;  1QXW A;  2EA2 A;  2GG3 A;  5CDE A;  2P9A A;  3TAV A;  3BIQ A;  2BWS A;  3PKC A;  2GA2 A;  1YVM A;  4B28 A;  1R5H A;  3PKB A;  4S2T P;  5FCF A;  2Q93 A;  5JI6 A;  2GG2 A;  1CHM A;  2P98 A;  2BB7 A;  4ZWP A; 
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