1I49 | Genus

Total Genus 97

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	97
sequence length	201
structure length	201
Chain Sequence	SRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. pubmed doi rcsb
molecule keywords	ARFAPTIN 2
total genus	97
structure length	201
sequence length	201
chains with identical sequence	B
ec nomenclature
pdb deposition date	2001-02-20

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.1270.60	Mainly Alpha	Up-down Bundle	Substrate Binding Domain Of Dnak; Chain:A; Domain 2	Arfaptin homology (AH) domain/BAR domain	1i49A00

3HAJA 4NQIA 3QWEA 4WPCA 1WDZA 2D4CA 4I1QA 5C5BA 3HAIA 4DYLA 1I4DA 3CAZA 3ABHA 2X3XA 2X3WA 3Q0KA 3Q84A 4DCNC 4WPEA 1I4LA 2Q12A 3HAHA 2Z0NA 2EFKA 2RAIA 3SYVA 1X03A 3LLLA 3ACOA 2FICA 1X04A 2D1LA 3QE6A 4H8SA 2RAKA 5C5BB 3OK8A 4NSWA 1URUA 3SOGA 2EFLA 2V0OA 3DYTA 3I2WA 2YKTA 2ELBA 3M3WA 2C08A 1I49A 4FZSA 2RAJA 4AKVA 4AVMA 2Z0OA 1Y2OA 4ATMA 2Z0VA 4BNEA 3PLTA 1ZWWA 3QNIA 1I4TA 3G9GA 2X3VA 2Q13A
chains in the Genus database with same CATH superfamily

4NQIA 4JWEA 3CZNA 3EJPA 1I4LA 4JNFA 3BVWA 2OBLA 1JQKA 3D4YA 2ND0A 1MJGA 1E1DA 2ELBA 4FZSA 3DDFA 4UDYX 3RV1A 2OZNB 2QKWA 1DKYA 4JN4A 2WYHA 3VEAA 2Z0NA 3BLBA 3QA8A 2F7OA 4NSWA 2EFLA 3OHXM 3DYTA 3DDGA 2YI8A 2WYIA 2Z0VA 1SU8A 4G6QA 3O3OB 3HAIA 3CAZA 2X3XA 1GNLA 2JNSA 4WPEA 4IWPA 2OW6A 3O3MB 2F7QA 1X03A 5KBPA 4IWQA 4M0MA 3EJSA 1SU6A 3EJRA 3ZEDA 3B53X 2PMRA 2YLAA 1TQVA 3C7NA 2F1AA 1SUFA 2YI9A 4AZIA 2OW7A 4F01A 1TQTA 3KAWA 4H6IA 2GA9D 3LVTA 3KAVA 3BUPA 2EWFA 2Z8YA 4D8JA 4B9QA 4EZSA 3T49A 2QFFA 4AKVA 2YIVX 1Y2OA 3EJUA 3DX1A 3O3NB 3T48A 4AZCA 3RPMA 4JWDA 2ZXQA 3DX4A 5C5BB 3LMFA 5E84A 4AZBA 4KIKB 3L3OM 3BVXA 2O0I1 2YIBA 2D4CA 4HR1B 3ER9B 3CV5A 1UPXA 2LXYA 2D1LA 4H8SA 2F1BA 4EZVA 3I2WA 1OA0A 1YWMA 3QNIA 1OA1A 3D2EA 3G9GA 2Q13A 1W9MA 3Q84A 1R33A 4EZWA 4H6HA 1LQ7A 3SOGA 2WINM 1E2UA 1O7DC 2OO2A 5FIGA 4IWOA 2MI7A 1OAOA 1WDZA 4IW0A 3FD9A 4AZHA 3EJTA 1QWUA 3DX0A 2F7RA 2RAJA 3A98A 1ZWWA 2X3VA 4JLCA 3QWEA 3D52A 3Q0KA 5FLEX 2OBMA 1PS3A 3CKDA 3B52X 3RV0A 3HAHA 1E9VA 3SYVA 3D50A 1HTYA 3ER8C 4EZQA 4F00A 4IM2A 2Z0OA 4FZPA 3BUBA 3BVTA 2ND1A 1I4DA 2YL8A 3BVVA 3D4ZA 2GF4A 3I01A 3QNJA 2LM0A 3CVRA 3M3WA 1GNTA 4IM3A 4AZGA 3F7WA 1HXKA 3L3PA 4JWCA 2ALWA 4EZUA 4R5LA 1U00A 4FM3A 4EZNA 3OK8A 1TQUA 3BUIA 1I49A 3D51A 4JL9A 4ATMA 1I4TA 3CZSA 4DYLA 4DCNC 4R5JA 2N3KA 4EZOA 3I39X 3ACOA 2FICA 3T4AG 2YL5A 4AVMA 3T47A 4BNEA 3PLTA 3GI7A 4AZ5A 2F7PA 1DKXA 4I1QA 5C5BA 1TQWA 4EZXA 2X5CA 1O7DB 2X3WA 2PY6A 4KIKA 2Q12A 2EFKA 4EZPA 3LLLA 1X04A 1QWNA 3B51X 4PO2A 4HR1A 1URUA 4EZZA 3VEBA 4R5KA 1DKZA 1SU7A 4AZCB 2NCZA 3EJQA 1R5EA 3T46A 4E3CA 1R34A 2YL6A 1HWWA 4E81A 2YIAA 2KHOA 4IM0A 2F18A 4EZTA 1TQSA 3VKHA 4R5IA 2V0OA 4JWIA 3OWGA 3I04A 2C08A 5TKYA 4HY9A 2QXLA 3DPPA 3ERCC 1QX1A 3D2FA 2RAKA 4EZYA 3UITA 2YL9A 1ZYLA 4FZOA 1GN9A 2JNKA 3BVUA 4AZ7A 4JNEA 3DX2A 2FYVA 4EZRA 3BUDA 3HAJA 3KDRA 4WPCA 4AZ6A 2YLLA 3DPQA 2GAFD 3DX3A 4NPHA 2RAIA 4UDXX 3QE6A 3BUQA 2EX3B 2YKTA 4HYBA 2RT6A 3DPOA 4R5GA 3ABHA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3HAJ A;  4NQI A;  3QWE A;  4WPC A;  1WDZ A;  2D4C A;  4I1Q A;  5C5B A;  3HAI A;  4DYL A;  1I4D A;  3CAZ A;  3ABH A;  2X3X A;  2X3W A;  3Q0K A;  3Q84 A;  4DCN C;  4WPE A;  1I4L A;  2Q12 A;  3HAH A;  2Z0N A;  2EFK A;  2RAI A;  3SYV A;  1X03 A;  3LLL A;  3ACO A;  2FIC A;  1X04 A;  2D1L A;  3QE6 A;  4H8S A;  2RAK A;  5C5B B;  3OK8 A;  4NSW A;  1URU A;  3SOG A;  2EFL A;  2V0O A;  3DYT A;  3I2W A;  2YKT A;  2ELB A;  3M3W A;  2C08 A;  1I49 A;  4FZS A;  2RAJ A;  4AKV A;  4AVM A;  2Z0O A;  1Y2O A;  4ATM A;  2Z0V A;  4BNE A;  3PLT A;  1ZWW A;  3QNI A;  1I4T A;  3G9G A;  2X3V A;  2Q13 A; 
#chains in the Genus database with same CATH topology
 4NQI A;  4JWE A;  3CZN A;  3EJP A;  1I4L A;  4JNF A;  3BVW A;  2OBL A;  1JQK A;  3D4Y A;  2ND0 A;  1MJG A;  1E1D A;  2ELB A;  4FZS A;  3DDF A;  4UDY X;  3RV1 A;  2OZN B;  2QKW A;  1DKY A;  4JN4 A;  2WYH A;  3VEA A;  2Z0N A;  3BLB A;  3QA8 A;  2F7O A;  4NSW A;  2EFL A;  3OHX M;  3DYT A;  3DDG A;  2YI8 A;  2WYI A;  2Z0V A;  1SU8 A;  4G6Q A;  3O3O B;  3HAI A;  3CAZ A;  2X3X A;  1GNL A;  2JNS A;  4WPE A;  4IWP A;  2OW6 A;  3O3M B;  2F7Q A;  1X03 A;  5KBP A;  4IWQ A;  4M0M A;  3EJS A;  1SU6 A;  3EJR A;  3ZED A;  3B53 X;  2PMR A;  2YLA A;  1TQV A;  3C7N A;  2F1A A;  1SUF A;  2YI9 A;  4AZI A;  2OW7 A;  4F01 A;  1TQT A;  3KAW A;  4H6I A;  2GA9 D;  3LVT A;  3KAV A;  3BUP A;  2EWF A;  2Z8Y A;  4D8J A;  4B9Q A;  4EZS A;  3T49 A;  2QFF A;  4AKV A;  2YIV X;  1Y2O A;  3EJU A;  3DX1 A;  3O3N B;  3T48 A;  4AZC A;  3RPM A;  4JWD A;  2ZXQ A;  3DX4 A;  5C5B B;  3LMF A;  5E84 A;  4AZB A;  4KIK B;  3L3O M;  3BVX A;  2O0I 1;  2YIB A;  2D4C A;  4HR1 B;  3ER9 B;  3CV5 A;  1UPX A;  2LXY A;  2D1L A;  4H8S A;  2F1B A;  4EZV A;  3I2W A;  1OA0 A;  1YWM A;  3QNI A;  1OA1 A;  3D2E A;  3G9G A;  2Q13 A;  1W9M A;  3Q84 A;  1R33 A;  4EZW A;  4H6H A;  1LQ7 A;  3SOG A;  2WIN M;  1E2U A;  1O7D C;  2OO2 A;  5FIG A;  4IWO A;  2MI7 A;  1OAO A;  1WDZ A;  4IW0 A;  3FD9 A;  4AZH A;  3EJT A;  1QWU A;  3DX0 A;  2F7R A;  2RAJ A;  3A98 A;  1ZWW A;  2X3V A;  4JLC A;  3QWE A;  3D52 A;  3Q0K A;  5FLE X;  2OBM A;  1PS3 A;  3CKD A;  3B52 X;  3RV0 A;  3HAH A;  1E9V A;  3SYV A;  3D50 A;  1HTY A;  3ER8 C;  4EZQ A;  4F00 A;  4IM2 A;  2Z0O A;  4FZP A;  3BUB A;  3BVT A;  2ND1 A;  1I4D A;  2YL8 A;  3BVV A;  3D4Z A;  2GF4 A;  3I01 A;  3QNJ A;  2LM0 A;  3CVR A;  3M3W A;  1GNT A;  4IM3 A;  4AZG A;  3F7W A;  1HXK A;  3L3P A;  4JWC A;  2ALW A;  4EZU A;  4R5L A;  1U00 A;  4FM3 A;  4EZN A;  3OK8 A;  1TQU A;  3BUI A;  1I49 A;  3D51 A;  4JL9 A;  4ATM A;  1I4T A;  3CZS A;  4DYL A;  4DCN C;  4R5J A;  2N3K A;  4EZO A;  3I39 X;  3ACO A;  2FIC A;  3T4A G;  2YL5 A;  4AVM A;  3T47 A;  4BNE A;  3PLT A;  3GI7 A;  4AZ5 A;  2F7P A;  1DKX A;  4I1Q A;  5C5B A;  1TQW A;  4EZX A;  2X5C A;  1O7D B;  2X3W A;  2PY6 A;  4KIK A;  2Q12 A;  2EFK A;  4EZP A;  3LLL A;  1X04 A;  1QWN A;  3B51 X;  4PO2 A;  4HR1 A;  1URU A;  4EZZ A;  3VEB A;  4R5K A;  1DKZ A;  1SU7 A;  4AZC B;  2NCZ A;  3EJQ A;  1R5E A;  3T46 A;  4E3C A;  1R34 A;  2YL6 A;  1HWW A;  4E81 A;  2YIA A;  2KHO A;  4IM0 A;  2F18 A;  4EZT A;  1TQS A;  3VKH A;  4R5I A;  2V0O A;  4JWI A;  3OWG A;  3I04 A;  2C08 A;  5TKY A;  4HY9 A;  2QXL A;  3DPP A;  3ERC C;  1QX1 A;  3D2F A;  2RAK A;  4EZY A;  3UIT A;  2YL9 A;  1ZYL A;  4FZO A;  1GN9 A;  2JNK A;  3BVU A;  4AZ7 A;  4JNE A;  3DX2 A;  2FYV A;  4EZR A;  3BUD A;  3HAJ A;  3KDR A;  4WPC A;  4AZ6 A;  2YLL A;  3DPQ A;  2GAF D;  3DX3 A;  4NPH A;  2RAI A;  4UDX X;  3QE6 A;  3BUQ A;  2EX3 B;  2YKT A;  4HYB A;  2RT6 A;  3DPO A;  4R5G A;  3ABH A; 
#chains in the Genus database with same CATH homology
 3HAJ A;  4NQI A;  3QWE A;  4WPC A;  1WDZ A;  2D4C A;  4I1Q A;  5C5B A;  3HAI A;  4DYL A;  1I4D A;  3CAZ A;  3ABH A;  2X3X A;  2X3W A;  3Q0K A;  3Q84 A;  4DCN C;  4WPE A;  1I4L A;  2Q12 A;  3HAH A;  2Z0N A;  2EFK A;  2RAI A;  3SYV A;  1X03 A;  3LLL A;  3ACO A;  2FIC A;  1X04 A;  2D1L A;  3QE6 A;  4H8S A;  2RAK A;  5C5B B;  3OK8 A;  4NSW A;  1URU A;  3SOG A;  2EFL A;  2V0O A;  3DYT A;  3I2W A;  2YKT A;  2ELB A;  3M3W A;  2C08 A;  1I49 A;  4FZS A;  2RAJ A;  4AKV A;  4AVM A;  2Z0O A;  1Y2O A;  4ATM A;  2Z0V A;  4BNE A;  3PLT A;  1ZWW A;  3QNI A;  1I4T A;  3G9G A;  2X3V A;  2Q13 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1I49A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN