3M3WA

Crystal strcuture of mouse pacsin3 bar domain mutant
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
288
structure length
280
Chain Sequence
GSFWEAGNYRRTVQRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGAVEKGPQYGTLEKAWHAFFTAAERLSELHLEVREKLHGPDSERVRTWQRGAFHGFRASRAAEDGFRKAQKPWLKRLKEVEASKKSYHTARKDEKTAQTRESHAKADSSMQLRKLQERVGRCTKEAEKMKTQYEQTLAELNRYTPRYMEDMEQAFESCQAAERQRLLFFKDVLLTLHQHLDLSSSDKFHELHRDLQQSIEAASDEEDLRWWRSTHGPGMAMNWPQFEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords Protein kinase C and casein kinase II substrate protein 3
total genus 112
structure length 280
sequence length 288
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3m3wA01
4AKVA 3LLLA 4FZSA 2X3WA 4AVMA 2Z0NA 4WPEA 3SOGA 4ATMA 1WDZA 3QNIA 2Q13A 3G9GA 2D4CA 2RAJA 2D1LA 2X3VA 3DYTA 3QWEA 3SYVA 5C5BA 4H8SA 3HAHA 2RAKA 3ABHA 2V0OA 3PLTA 2X3XA 3HAIA 4NQIA 4WPCA 1X04A 1I4LA 2Q12A 3I2WA 2FICA 2RAIA 2Z0VA 2EFKA 2Z0OA 2C08A 2EFLA 1URUA 5C5BB 3M3WA 1I49A 2ELBA 4DYLA 3Q84A 4I1QA 4BNEA 3HAJA 4DCNC 1ZWWA 2YKTA 3QE6A 3ACOA 3OK8A 1I4DA 3Q0KA 4NSWA 1Y2OA 3CAZA 1X03A 1I4TA
chains in the Genus database with same CATH superfamily
3T48A 3FD9A 1TQSA 2OO2A 2YL6A 3DDGA 2OBLA 3O3NB 4AZ6A 2ALWA 3EJPA 2Z0OA 2WYIA 5FIGA 1LQ7A 1DKYA 3DX0A 3BVXA 1I4TA 2F7QA 4IM3A 4AVMA 3SOGA 5FLEX 3T47A 4H8SA 4JL9A 3T49A 2EFLA 2OW6A 1URUA 2F18A 4JWEA 2F7RA 4G6QA 2ZXQA 3CZSA 3I01A 3QWEA 2KHOA 5KBPA 4F00A 4EZQA 4EZXA 2FICA 3Q84A 4IM2A 3QE6A 4AZ7A 4EZRA 5C5BA 2LXYA 3EJQA 2X5CA 3B53X 1QWUA 4ATMA 3T46A 2QXLA 3SYVA 1HXKA 2YL8A 3CKDA 4R5JA 3LVTA 2X3XA 3HAIA 3KAWA 1QWNA 3D4YA 4IWOA 4AZIA 4EZZA 3M3WA 2LM0A 4BNEA 2PMRA 4JLCA 1R34A 2X3WA 1TQTA 4HR1A 3D2EA 3EJSA 1O7DB 2RAKA 4EZPA 2QFFA 4AZCB 2Q12A 1E9VA 3VEBA 2EFKA 4E3CA 4HYBA 3BUBA 3B51X 3DX4A 4R5KA 4FZSA 1SU7A 2ND0A 4FZPA 4EZVA 1WDZA 4JNFA 1GNLA 4AZGA 2F1BA 4H6HA 4PO2A 3ERCC 2C08A 4JN4A 4KIKB 4DCNC 1U00A 4NQIA 2GF4A 4D8JA 4EZOA 1YWMA 1TQUA 3G9GA 2EX3B 3UITA 2PY6A 3GI7A 2YIVX 3ABHA 1DKXA 1I4LA 2YI9A 3D51A 2YL5A 3I04A 3CVRA 2F1AA 2OW7A 3HAJA 3ER9B 3QNIA 3D4ZA 1GN9A 2O0I1 2RAJA 3BUPA 3D52A 2WYHA 3DYTA 3DDFA 3HAHA 4AZHA 3BLBA 2YLLA 1TQWA 3D2FA 4EZTA 2ELBA 4IWQA 4JWCA 3OK8A 2JNSA 1ZYLA 1X03A 3DX3A 4R5LA 3VEAA 4JNEA 1SU8A 3KAVA 1HWWA 1OA0A 2X3VA 3RPMA 2V0OA 1HTYA 2Z8YA 3OWGA 3DX2A 2RT6A 4M0MA 1E2UA 1UPXA 3BUIA 3F7WA 1R5EA 1E1DA 2Q13A 3CZNA 3CV5A 3PLTA 3DPOA 2F7OA 3I2WA 3OHXM 1TQVA 4EZYA 4JWIA 3D50A 2WINM 1MJGA 4JWDA 2F7PA 3LLLA 3DPPA 2D4CA 3EJUA 3EJRA 4E81A 2EWFA 3O3OB 4AZ5A 3BVWA 1ZWWA 2YKTA 3QA8A 3BVUA 3BUQA 4EZSA 4HY9A 2D1LA 3KDRA 3BVVA 4B9QA 1GNTA 4AZCA 1O7DC 4H6IA 5C5BB 1I49A 3T4AG 3QNJA 3DPQA 1PS3A 4EZUA 4NPHA 1W9MA 3L3OM 1QX1A 4FZOA 4R5IA 3EJTA 2YI8A 3ZEDA 2QKWA 3I39X 4IW0A 2OZNB 2RAIA 2ND1A 4KIKA 4HR1B 5E84A 1Y2OA 4AKVA 4UDYX 3BUDA 4F01A 5TKYA 3RV1A 2N3KA 2FYVA 2GAFD 3ER8C 2YIAA 4IWPA 4AZBA 3CAZA 3L3PA 2YLAA 3A98A 4WPEA 2OBMA 2YL9A 2NCZA 1DKZA 4R5GA 1X04A 1SU6A 3B52X 4DYLA 4I1QA 1R33A 1I4DA 3DX1A 1JQKA 4EZWA 3VKHA 2Z0NA 4IM0A 3RV0A 4EZNA 3BVTA 1OA1A 2YIBA 2GA9D 3C7NA 4WPCA 2Z0VA 1OAOA 4UDXX 1SUFA 3LMFA 2JNKA 2MI7A 3Q0KA 4NSWA 4FM3A 3ACOA 3O3MB
chains in the Genus database with same CATH topology
4AKVA 3LLLA 4FZSA 2X3WA 4AVMA 2Z0NA 4WPEA 3SOGA 4ATMA 1WDZA 3QNIA 2Q13A 3G9GA 2D4CA 2RAJA 2D1LA 2X3VA 3DYTA 3QWEA 3SYVA 5C5BA 4H8SA 3HAHA 2RAKA 3ABHA 2V0OA 3PLTA 2X3XA 3HAIA 4NQIA 4WPCA 1X04A 1I4LA 2Q12A 3I2WA 2FICA 2RAIA 2Z0VA 2EFKA 2Z0OA 2C08A 2EFLA 1URUA 5C5BB 3M3WA 1I49A 2ELBA 4DYLA 3Q84A 4I1QA 4BNEA 3HAJA 4DCNC 1ZWWA 2YKTA 3QE6A 3ACOA 3OK8A 1I4DA 3Q0KA 4NSWA 1Y2OA 3CAZA 1X03A 1I4TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AKV A;  3LLL A;  4FZS A;  2X3W A;  4AVM A;  2Z0N A;  4WPE A;  3SOG A;  4ATM A;  1WDZ A;  3QNI A;  2Q13 A;  3G9G A;  2D4C A;  2RAJ A;  2D1L A;  2X3V A;  3DYT A;  3QWE A;  3SYV A;  5C5B A;  4H8S A;  3HAH A;  2RAK A;  3ABH A;  2V0O A;  3PLT A;  2X3X A;  3HAI A;  4NQI A;  4WPC A;  1X04 A;  1I4L A;  2Q12 A;  3I2W A;  2FIC A;  2RAI A;  2Z0V A;  2EFK A;  2Z0O A;  2C08 A;  2EFL A;  1URU A;  5C5B B;  3M3W A;  1I49 A;  2ELB A;  4DYL A;  3Q84 A;  4I1Q A;  4BNE A;  3HAJ A;  4DCN C;  1ZWW A;  2YKT A;  3QE6 A;  3ACO A;  3OK8 A;  1I4D A;  3Q0K A;  4NSW A;  1Y2O A;  3CAZ A;  1X03 A;  1I4T A; 
#chains in the Genus database with same CATH topology
 3T48 A;  3FD9 A;  1TQS A;  2OO2 A;  2YL6 A;  3DDG A;  2OBL A;  3O3N B;  4AZ6 A;  2ALW A;  3EJP A;  2Z0O A;  2WYI A;  5FIG A;  1LQ7 A;  1DKY A;  3DX0 A;  3BVX A;  1I4T A;  2F7Q A;  4IM3 A;  4AVM A;  3SOG A;  5FLE X;  3T47 A;  4H8S A;  4JL9 A;  3T49 A;  2EFL A;  2OW6 A;  1URU A;  2F18 A;  4JWE A;  2F7R A;  4G6Q A;  2ZXQ A;  3CZS A;  3I01 A;  3QWE A;  2KHO A;  5KBP A;  4F00 A;  4EZQ A;  4EZX A;  2FIC A;  3Q84 A;  4IM2 A;  3QE6 A;  4AZ7 A;  4EZR A;  5C5B A;  2LXY A;  3EJQ A;  2X5C A;  3B53 X;  1QWU A;  4ATM A;  3T46 A;  2QXL A;  3SYV A;  1HXK A;  2YL8 A;  3CKD A;  4R5J A;  3LVT A;  2X3X A;  3HAI A;  3KAW A;  1QWN A;  3D4Y A;  4IWO A;  4AZI A;  4EZZ A;  3M3W A;  2LM0 A;  4BNE A;  2PMR A;  4JLC A;  1R34 A;  2X3W A;  1TQT A;  4HR1 A;  3D2E A;  3EJS A;  1O7D B;  2RAK A;  4EZP A;  2QFF A;  4AZC B;  2Q12 A;  1E9V A;  3VEB A;  2EFK A;  4E3C A;  4HYB A;  3BUB A;  3B51 X;  3DX4 A;  4R5K A;  4FZS A;  1SU7 A;  2ND0 A;  4FZP A;  4EZV A;  1WDZ A;  4JNF A;  1GNL A;  4AZG A;  2F1B A;  4H6H A;  4PO2 A;  3ERC C;  2C08 A;  4JN4 A;  4KIK B;  4DCN C;  1U00 A;  4NQI A;  2GF4 A;  4D8J A;  4EZO A;  1YWM A;  1TQU A;  3G9G A;  2EX3 B;  3UIT A;  2PY6 A;  3GI7 A;  2YIV X;  3ABH A;  1DKX A;  1I4L A;  2YI9 A;  3D51 A;  2YL5 A;  3I04 A;  3CVR A;  2F1A A;  2OW7 A;  3HAJ A;  3ER9 B;  3QNI A;  3D4Z A;  1GN9 A;  2O0I 1;  2RAJ A;  3BUP A;  3D52 A;  2WYH A;  3DYT A;  3DDF A;  3HAH A;  4AZH A;  3BLB A;  2YLL A;  1TQW A;  3D2F A;  4EZT A;  2ELB A;  4IWQ A;  4JWC A;  3OK8 A;  2JNS A;  1ZYL A;  1X03 A;  3DX3 A;  4R5L A;  3VEA A;  4JNE A;  1SU8 A;  3KAV A;  1HWW A;  1OA0 A;  2X3V A;  3RPM A;  2V0O A;  1HTY A;  2Z8Y A;  3OWG A;  3DX2 A;  2RT6 A;  4M0M A;  1E2U A;  1UPX A;  3BUI A;  3F7W A;  1R5E A;  1E1D A;  2Q13 A;  3CZN A;  3CV5 A;  3PLT A;  3DPO A;  2F7O A;  3I2W A;  3OHX M;  1TQV A;  4EZY A;  4JWI A;  3D50 A;  2WIN M;  1MJG A;  4JWD A;  2F7P A;  3LLL A;  3DPP A;  2D4C A;  3EJU A;  3EJR A;  4E81 A;  2EWF A;  3O3O B;  4AZ5 A;  3BVW A;  1ZWW A;  2YKT A;  3QA8 A;  3BVU A;  3BUQ A;  4EZS A;  4HY9 A;  2D1L A;  3KDR A;  3BVV A;  4B9Q A;  1GNT A;  4AZC A;  1O7D C;  4H6I A;  5C5B B;  1I49 A;  3T4A G;  3QNJ A;  3DPQ A;  1PS3 A;  4EZU A;  4NPH A;  1W9M A;  3L3O M;  1QX1 A;  4FZO A;  4R5I A;  3EJT A;  2YI8 A;  3ZED A;  2QKW A;  3I39 X;  4IW0 A;  2OZN B;  2RAI A;  2ND1 A;  4KIK A;  4HR1 B;  5E84 A;  1Y2O A;  4AKV A;  4UDY X;  3BUD A;  4F01 A;  5TKY A;  3RV1 A;  2N3K A;  2FYV A;  2GAF D;  3ER8 C;  2YIA A;  4IWP A;  4AZB A;  3CAZ A;  3L3P A;  2YLA A;  3A98 A;  4WPE A;  2OBM A;  2YL9 A;  2NCZ A;  1DKZ A;  4R5G A;  1X04 A;  1SU6 A;  3B52 X;  4DYL A;  4I1Q A;  1R33 A;  1I4D A;  3DX1 A;  1JQK A;  4EZW A;  3VKH A;  2Z0N A;  4IM0 A;  3RV0 A;  4EZN A;  3BVT A;  1OA1 A;  2YIB A;  2GA9 D;  3C7N A;  4WPC A;  2Z0V A;  1OAO A;  4UDX X;  1SUF A;  3LMF A;  2JNK A;  2MI7 A;  3Q0K A;  4NSW A;  4FM3 A;  3ACO A;  3O3M B; 
#chains in the Genus database with same CATH homology
 4AKV A;  3LLL A;  4FZS A;  2X3W A;  4AVM A;  2Z0N A;  4WPE A;  3SOG A;  4ATM A;  1WDZ A;  3QNI A;  2Q13 A;  3G9G A;  2D4C A;  2RAJ A;  2D1L A;  2X3V A;  3DYT A;  3QWE A;  3SYV A;  5C5B A;  4H8S A;  3HAH A;  2RAK A;  3ABH A;  2V0O A;  3PLT A;  2X3X A;  3HAI A;  4NQI A;  4WPC A;  1X04 A;  1I4L A;  2Q12 A;  3I2W A;  2FIC A;  2RAI A;  2Z0V A;  2EFK A;  2Z0O A;  2C08 A;  2EFL A;  1URU A;  5C5B B;  3M3W A;  1I49 A;  2ELB A;  4DYL A;  3Q84 A;  4I1Q A;  4BNE A;  3HAJ A;  4DCN C;  1ZWW A;  2YKT A;  3QE6 A;  3ACO A;  3OK8 A;  1I4D A;  3Q0K A;  4NSW A;  1Y2O A;  3CAZ A;  1X03 A;  1I4T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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