2Z0NA

Crystal structure of appl1-bar domain
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
243
structure length
235
Chain Sequence
b'LEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLLKEYEKQEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIEDLE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DCC-interacting protein 13-alpha
publication title Crystal structure of APPL1-BAR domain
rcsb
source organism Homo sapiens
molecule tags Signaling protein
total genus 94
structure length 235
sequence length 243
ec nomenclature
pdb deposition date 2007-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16746 BAR_3 BAR domain of APPL family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2z0nA00
1WDZA 4AKVA 4DYLA 4I1QA 1URUA 2RAJA 2Q12A 1I49A 2Z0NA 1ZWWA 3ABHA 2X3WA 2Z0OA 2Q13A 4FZSA 1I4LA 1I4TA 2V0OA 3G9GA 3SOGA 4AVMA 4BNEA 1I4DA 3QWEA 4ATMA 2EFKA 2C08A 3DYTA 3PLTA 4WPCA 4NSWA 2X3XA 3QE6A 3M3WA 3QNIA 2Z0VA 3I2WA 1Y2OA 2YKTA 3SYVA 3CAZA 5C5BA 3Q84A 3HAIA 2X3VA 5C5BB 3ACOA 3HAJA 4NQIA 2RAIA 2D4CA 3HAHA 3OK8A 2FICA 2RAKA 2D1LA 2ELBA 4WPEA 1X04A 2EFLA 4DCNC 3Q0KA 3LLLA 4H8SA 1X03A
chains in the Genus database with same CATH superfamily
1LQ7A 4EZOA 4I1QA 1URUA 1I49A 4EZSA 5TKYA 2F1AA 4WPCA 2YI9A 3F7WA 3ER9B 5C5BA 1R33A 1DKYA 2YLLA 4JWEA 3DDFA 1U00A 3BUPA 2YLAA 1QWNA 2EX3B 3LMFA 2JNKA 2GF4A 4EZZA 4B9QA 3SYVA 2RT6A 5C5BB 3VEBA 3KAVA 3HAHA 4H6IA 2PY6A 2FICA 2ZXQA 4E81A 3BVWA 5FLEX 3T46A 2YL5A 2EWFA 4EZUA 1OA1A 2Z0VA 1X04A 4E3CA 1DKZA 3BVTA 4PO2A 3VKHA 3B52X 3BVVA 2OZNB 4HY9A 2LM0A 1I4LA 3C7NA 1I4TA 3EJPA 1HXKA 2N3KA 4NSWA 3QNIA 4EZYA 1E2UA 2WYHA 4JWIA 4NQIA 2RAIA 3CZSA 4EZVA 2RAKA 4R5LA 2D1LA 2EFLA 3D50A 4KIKB 1E1DA 2YL8A 2QKWA 3B53X 4R5IA 2Z0NA 3D4ZA 3DX1A 2OO2A 2X3WA 2Q13A 2F7QA 1OAOA 2X3XA 2F18A 1R34A 3D2EA 2OBMA 2F1BA 2ELBA 3T47A 3ZEDA 3CV5A 2Z0OA 1GNTA 2KHOA 4AZCA 4EZRA 3EJQA 1ZYLA 2YI8A 2X3VA 4IM2A 3OK8A 3GI7A 3LLLA 4AZ7A 4JN4A 2LXYA 4R5JA 3BUDA 3SOGA 3KAWA 1SUFA 2EFKA 2F7PA 4AZCB 3T48A 4HR1A 3I2WA 2D4CA 1GNLA 4DCNC 2YL9A 2WYIA 4H8SA 4UDYX 1ZWWA 4AZIA 5KBPA 3BUBA 4NPHA 4IM3A 4JL9A 4F01A 2F7OA 2YL6A 2OW7A 1OA0A 1DKXA 1GN9A 4D8JA 4IWQA 3D2FA 4JNEA 1I4DA 2JNSA 3DYTA 3PLTA 1E9VA 1O7DB 2O0I1 3O3OB 4AZ5A 4H6HA 4FM3A 3B51X 3VEAA 1TQUA 3O3MB 4FZSA 3A98A 4BNEA 3I39X 1TQSA 3BVXA 4R5GA 3KDRA 4HYBA 1W9MA 3DX4A 4EZXA 2GAFD 4AZBA 3DX3A 3L3PA 2Z8YA 4IW0A 3EJRA 4AZGA 3LVTA 3QWEA 2QFFA 3QA8A 3RV0A 2ND1A 2YIVX 3CKDA 4WPEA 3RV1A 5E84A 2GA9D 1JQKA 3UITA 3DDGA 3L3OM 3CVRA 3G9GA 4AVMA 3T4AG 2OW6A 2WINM 4EZPA 2OBLA 3DPQA 4UDXX 4JLCA 4AZ6A 3CZNA 4EZTA 2X5CA 4JWDA 3I04A 3DPOA 3BUQA 1R5EA 1QX1A 2PMRA 4HR1B 3CAZA 3D51A 2YIAA 3Q84A 4G6QA 3BUIA 4JNFA 1SU6A 2F7RA 3OHXM 3QNJA 1WDZA 2QXLA 1YWMA 4IM0A 1TQVA 2YIBA 3ABHA 1O7DC 2ALWA 3EJSA 4ATMA 4FZPA 4IWOA 3ERCC 3FD9A 3M3WA 3BLBA 1HWWA 1SU7A 1QWUA 4KIKA 3Q0KA 1X03A 1UPXA 3D52A 1PS3A 4AZHA 4JWCA 4IWPA 3DPPA 2V0OA 4EZWA 3O3NB 4R5KA 2ND0A 3QE6A 1Y2OA 2YKTA 2MI7A 3HAIA 3ACOA 3HAJA 4EZQA 2FYVA 3OWGA 3EJUA 3EJTA 4AKVA 4DYLA 1HTYA 2RAJA 2Q12A 5FIGA 3T49A 3I01A 3ER8C 1TQWA 1TQTA 2C08A 4M0MA 1SU8A 4EZNA 3D4YA 1MJGA 3BVUA 3DX0A 3DX2A 4F00A 3RPMA 2NCZA 4FZOA
chains in the Genus database with same CATH topology
1WDZA 4AKVA 4DYLA 4I1QA 1URUA 2RAJA 2Q12A 1I49A 2Z0NA 1ZWWA 3ABHA 2X3WA 2Z0OA 2Q13A 4FZSA 1I4LA 1I4TA 2V0OA 3G9GA 3SOGA 4AVMA 4BNEA 1I4DA 3QWEA 4ATMA 2EFKA 2C08A 3DYTA 3PLTA 4WPCA 4NSWA 2X3XA 3QE6A 3M3WA 3QNIA 2Z0VA 3I2WA 1Y2OA 2YKTA 3SYVA 3CAZA 5C5BA 3Q84A 3HAIA 2X3VA 5C5BB 3ACOA 3HAJA 4NQIA 2RAIA 2D4CA 3HAHA 3OK8A 2FICA 2RAKA 2D1LA 2ELBA 4WPEA 1X04A 2EFLA 4DCNC 3Q0KA 3LLLA 4H8SA 1X03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WDZ A;  4AKV A;  4DYL A;  4I1Q A;  1URU A;  2RAJ A;  2Q12 A;  1I49 A;  2Z0N A;  1ZWW A;  3ABH A;  2X3W A;  2Z0O A;  2Q13 A;  4FZS A;  1I4L A;  1I4T A;  2V0O A;  3G9G A;  3SOG A;  4AVM A;  4BNE A;  1I4D A;  3QWE A;  4ATM A;  2EFK A;  2C08 A;  3DYT A;  3PLT A;  4WPC A;  4NSW A;  2X3X A;  3QE6 A;  3M3W A;  3QNI A;  2Z0V A;  3I2W A;  1Y2O A;  2YKT A;  3SYV A;  3CAZ A;  5C5B A;  3Q84 A;  3HAI A;  2X3V A;  5C5B B;  3ACO A;  3HAJ A;  4NQI A;  2RAI A;  2D4C A;  3HAH A;  3OK8 A;  2FIC A;  2RAK A;  2D1L A;  2ELB A;  4WPE A;  1X04 A;  2EFL A;  4DCN C;  3Q0K A;  3LLL A;  4H8S A;  1X03 A; 
#chains in the Genus database with same CATH topology
 1LQ7 A;  4EZO A;  4I1Q A;  1URU A;  1I49 A;  4EZS A;  5TKY A;  2F1A A;  4WPC A;  2YI9 A;  3F7W A;  3ER9 B;  5C5B A;  1R33 A;  1DKY A;  2YLL A;  4JWE A;  3DDF A;  1U00 A;  3BUP A;  2YLA A;  1QWN A;  2EX3 B;  3LMF A;  2JNK A;  2GF4 A;  4EZZ A;  4B9Q A;  3SYV A;  2RT6 A;  5C5B B;  3VEB A;  3KAV A;  3HAH A;  4H6I A;  2PY6 A;  2FIC A;  2ZXQ A;  4E81 A;  3BVW A;  5FLE X;  3T46 A;  2YL5 A;  2EWF A;  4EZU A;  1OA1 A;  2Z0V A;  1X04 A;  4E3C A;  1DKZ A;  3BVT A;  4PO2 A;  3VKH A;  3B52 X;  3BVV A;  2OZN B;  4HY9 A;  2LM0 A;  1I4L A;  3C7N A;  1I4T A;  3EJP A;  1HXK A;  2N3K A;  4NSW A;  3QNI A;  4EZY A;  1E2U A;  2WYH A;  4JWI A;  4NQI A;  2RAI A;  3CZS A;  4EZV A;  2RAK A;  4R5L A;  2D1L A;  2EFL A;  3D50 A;  4KIK B;  1E1D A;  2YL8 A;  2QKW A;  3B53 X;  4R5I A;  2Z0N A;  3D4Z A;  3DX1 A;  2OO2 A;  2X3W A;  2Q13 A;  2F7Q A;  1OAO A;  2X3X A;  2F18 A;  1R34 A;  3D2E A;  2OBM A;  2F1B A;  2ELB A;  3T47 A;  3ZED A;  3CV5 A;  2Z0O A;  1GNT A;  2KHO A;  4AZC A;  4EZR A;  3EJQ A;  1ZYL A;  2YI8 A;  2X3V A;  4IM2 A;  3OK8 A;  3GI7 A;  3LLL A;  4AZ7 A;  4JN4 A;  2LXY A;  4R5J A;  3BUD A;  3SOG A;  3KAW A;  1SUF A;  2EFK A;  2F7P A;  4AZC B;  3T48 A;  4HR1 A;  3I2W A;  2D4C A;  1GNL A;  4DCN C;  2YL9 A;  2WYI A;  4H8S A;  4UDY X;  1ZWW A;  4AZI A;  5KBP A;  3BUB A;  4NPH A;  4IM3 A;  4JL9 A;  4F01 A;  2F7O A;  2YL6 A;  2OW7 A;  1OA0 A;  1DKX A;  1GN9 A;  4D8J A;  4IWQ A;  3D2F A;  4JNE A;  1I4D A;  2JNS A;  3DYT A;  3PLT A;  1E9V A;  1O7D B;  2O0I 1;  3O3O B;  4AZ5 A;  4H6H A;  4FM3 A;  3B51 X;  3VEA A;  1TQU A;  3O3M B;  4FZS A;  3A98 A;  4BNE A;  3I39 X;  1TQS A;  3BVX A;  4R5G A;  3KDR A;  4HYB A;  1W9M A;  3DX4 A;  4EZX A;  2GAF D;  4AZB A;  3DX3 A;  3L3P A;  2Z8Y A;  4IW0 A;  3EJR A;  4AZG A;  3LVT A;  3QWE A;  2QFF A;  3QA8 A;  3RV0 A;  2ND1 A;  2YIV X;  3CKD A;  4WPE A;  3RV1 A;  5E84 A;  2GA9 D;  1JQK A;  3UIT A;  3DDG A;  3L3O M;  3CVR A;  3G9G A;  4AVM A;  3T4A G;  2OW6 A;  2WIN M;  4EZP A;  2OBL A;  3DPQ A;  4UDX X;  4JLC A;  4AZ6 A;  3CZN A;  4EZT A;  2X5C A;  4JWD A;  3I04 A;  3DPO A;  3BUQ A;  1R5E A;  1QX1 A;  2PMR A;  4HR1 B;  3CAZ A;  3D51 A;  2YIA A;  3Q84 A;  4G6Q A;  3BUI A;  4JNF A;  1SU6 A;  2F7R A;  3OHX M;  3QNJ A;  1WDZ A;  2QXL A;  1YWM A;  4IM0 A;  1TQV A;  2YIB A;  3ABH A;  1O7D C;  2ALW A;  3EJS A;  4ATM A;  4FZP A;  4IWO A;  3ERC C;  3FD9 A;  3M3W A;  3BLB A;  1HWW A;  1SU7 A;  1QWU A;  4KIK A;  3Q0K A;  1X03 A;  1UPX A;  3D52 A;  1PS3 A;  4AZH A;  4JWC A;  4IWP A;  3DPP A;  2V0O A;  4EZW A;  3O3N B;  4R5K A;  2ND0 A;  3QE6 A;  1Y2O A;  2YKT A;  2MI7 A;  3HAI A;  3ACO A;  3HAJ A;  4EZQ A;  2FYV A;  3OWG A;  3EJU A;  3EJT A;  4AKV A;  4DYL A;  1HTY A;  2RAJ A;  2Q12 A;  5FIG A;  3T49 A;  3I01 A;  3ER8 C;  1TQW A;  1TQT A;  2C08 A;  4M0M A;  1SU8 A;  4EZN A;  3D4Y A;  1MJG A;  3BVU A;  3DX0 A;  3DX2 A;  4F00 A;  3RPM A;  2NCZ A;  4FZO A; 
#chains in the Genus database with same CATH homology
 1WDZ A;  4AKV A;  4DYL A;  4I1Q A;  1URU A;  2RAJ A;  2Q12 A;  1I49 A;  2Z0N A;  1ZWW A;  3ABH A;  2X3W A;  2Z0O A;  2Q13 A;  4FZS A;  1I4L A;  1I4T A;  2V0O A;  3G9G A;  3SOG A;  4AVM A;  4BNE A;  1I4D A;  3QWE A;  4ATM A;  2EFK A;  2C08 A;  3DYT A;  3PLT A;  4WPC A;  4NSW A;  2X3X A;  3QE6 A;  3M3W A;  3QNI A;  2Z0V A;  3I2W A;  1Y2O A;  2YKT A;  3SYV A;  3CAZ A;  5C5B A;  3Q84 A;  3HAI A;  2X3V A;  5C5B B;  3ACO A;  3HAJ A;  4NQI A;  2RAI A;  2D4C A;  3HAH A;  3OK8 A;  2FIC A;  2RAK A;  2D1L A;  2ELB A;  4WPE A;  1X04 A;  2EFL A;  4DCN C;  3Q0K A;  3LLL A;  4H8S A;  1X03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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