2Z0NA

Crystal structure of appl1-bar domain
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
243
structure length
235
Chain Sequence
LEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLLKEYEKQEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIEDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords DCC-interacting protein 13-alpha
publication title Crystal structure of APPL1-BAR domain
rcsb
source organism Homo sapiens
total genus 94
structure length 235
sequence length 243
ec nomenclature
pdb deposition date 2007-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16746 BAR_3 BAR domain of APPL family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2z0nA00
3OK8A 3HAHA 4NQIA 1I4TA 2D4CA 3SOGA 3DYTA 4BNEA 1X04A 4ATMA 1I4DA 1WDZA 1ZWWA 2YKTA 3I2WA 4WPEA 2RAIA 2Q13A 2Q12A 2ELBA 2Z0NA 2Z0OA 3QE6A 5C5BA 3HAJA 3QNIA 1I4LA 3M3WA 2RAJA 3SYVA 2FICA 2EFLA 3Q84A 4AVMA 1I49A 2X3VA 3CAZA 4AKVA 1Y2OA 2V0OA 2RAKA 1X03A 2Z0VA 3LLLA 4DCNC 2X3WA 4WPCA 4FZSA 5C5BB 2C08A 3Q0KA 2D1LA 3QWEA 4DYLA 1URUA 4I1QA 3ABHA 3G9GA 3HAIA 3PLTA 4NSWA 2X3XA 4H8SA 3ACOA 2EFKA
chains in the Genus database with same CATH superfamily
4NQIA 2OO2A 4EZRA 2OW6A 3B52X 3QE6A 4R5KA 2JNSA 1Y2OA 3EJSA 4EZZA 2N3KA 1GN9A 4FZPA 4AZ6A 1ZYLA 3OK8A 3OWGA 1GNLA 2KHOA 4WPEA 1MJGA 1QWUA 3B53X 3QNIA 3Q84A 3BUIA 1R5EA 4HY9A 2F7OA 2YL5A 3D50A 2ND1A 4EZSA 3UITA 3DPOA 3BVXA 2FYVA 1YWMA 4JWDA 3ZEDA 3HAJA 3BUQA 1TQVA 2GF4A 3PLTA 1SU6A 4HYBA 5TKYA 3EJUA 4H6IA 3EJQA 2JNKA 1I4LA 1TQTA 4EZTA 3CAZA 4EZVA 4IM2A 3BVTA 3BUPA 4FZSA 1TQUA 2WYIA 4F01A 4AZBA 2Q13A 4EZXA 3C7NA 3RV0A 2QKWA 4AKVA 2YI9A 2RAKA 4DCNC 4HR1B 3CVRA 2X3WA 3BLBA 2PMRA 3ABHA 4H8SA 2EWFA 2PY6A 4B9QA 3HAHA 3DDGA 3O3OB 1WDZA 3ER8C 2ND0A 3VEBA 5KBPA 2MI7A 1LQ7A 3RPMA 2YIBA 2F1BA 2QFFA 4R5LA 2C08A 3Q0KA 1TQWA 2EFKA 3DYTA 1X04A 4H6HA 1ZWWA 3DDFA 2RAIA 2FICA 4EZNA 1JQKA 1DKYA 4E3CA 3L3OM 4EZOA 4F00A 2YIAA 4IM3A 3BVVA 3D2EA 4AZCB 2X3XA 1SUFA 4IWQA 2WYHA 4HR1A 2Z0OA 5C5BA 3DPPA 3VEAA 3DPQA 3T48A 3D52A 3EJTA 3FD9A 3DX0A 2O0I1 3GI7A 4AZIA 2F1AA 1OA0A 3LVTA 3SYVA 1HWWA 2F7RA 2V0OA 1X03A 2Z0VA 2LM0A 3I39X 3OHXM 3EJPA 1OAOA 3QWEA 4EZUA 3D4ZA 4M0MA 3L3PA 3D51A 3CKDA 4BNEA 3EJRA 3BUBA 1O7DB 2F18A 2EFLA 2QXLA 4IWPA 4AZCA 2YLAA 4UDXX 1R33A 3D2FA 3T46A 1SU7A 4KIKB 1OA1A 5FIGA 3T4AG 2ALWA 1SU8A 4WPCA 1E1DA 5C5BB 3O3MB 3DX3A 1QWNA 1I4TA 4R5IA 2YKTA 4EZPA 2Q12A 2OW7A 2F7PA 3QNJA 1I49A 1U00A 1R34A 3DX1A 3F7WA 4NPHA 3I04A 4JWEA 1URUA 3RV1A 2Z8YA 3QA8A 3VKHA 4JWIA 1TQSA 1I4DA 1W9MA 4AZHA 1HTYA 2YL6A 4JLCA 4JN4A 1DKXA 3O3NB 2YL8A 3KAWA 4E81A 2EX3B 3CZSA 2D4CA 3SOGA 4IW0A 4ATMA 2OBLA 4KIKA 2X5CA 2Z0NA 2RAJA 1UPXA 2RT6A 4AZ5A 2GA9D 2YL9A 4UDYX 4I1QA 4NSWA 3ACOA 1DKZA 2GAFD 3I2WA 4FZOA 4JWCA 4AZGA 2OZNB 4FM3A 3LMFA 3I01A 1O7DC 2YLLA 4AVMA 2X3VA 4G6QA 4EZQA 1PS3A 4DYLA 4JNFA 1E9VA 4JNEA 2OBMA 4EZYA 1E2UA 3B51X 4EZWA 3BUDA 2F7QA 3KDRA 4AZ7A 3CV5A 2YIVX 3LLLA 4R5GA 3KAVA 4R5JA 2WINM 1QX1A 4D8JA 3G9GA 3HAIA 4JL9A 1HXKA 3BVWA 5FLEX 4IWOA 4PO2A 5E84A 3BVUA 4IM0A 3T47A 2YI8A 2ELBA 3A98A 3M3WA 3CZNA 1GNTA 3DX4A 3ERCC 2D1LA 3ER9B 2ZXQA 3DX2A 2NCZA 2LXYA 3D4YA 3T49A
chains in the Genus database with same CATH topology
3OK8A 3HAHA 4NQIA 1I4TA 2D4CA 3SOGA 3DYTA 4BNEA 1X04A 4ATMA 1I4DA 1WDZA 1ZWWA 2YKTA 3I2WA 4WPEA 2RAIA 2Q13A 2Q12A 2ELBA 2Z0NA 2Z0OA 3QE6A 5C5BA 3HAJA 3QNIA 1I4LA 3M3WA 2RAJA 3SYVA 2FICA 2EFLA 3Q84A 4AVMA 1I49A 2X3VA 3CAZA 4AKVA 1Y2OA 2V0OA 2RAKA 1X03A 2Z0VA 3LLLA 4DCNC 2X3WA 4WPCA 4FZSA 5C5BB 2C08A 3Q0KA 2D1LA 3QWEA 4DYLA 1URUA 4I1QA 3ABHA 3G9GA 3HAIA 3PLTA 4NSWA 2X3XA 4H8SA 3ACOA 2EFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OK8 A;  3HAH A;  4NQI A;  1I4T A;  2D4C A;  3SOG A;  3DYT A;  4BNE A;  1X04 A;  4ATM A;  1I4D A;  1WDZ A;  1ZWW A;  2YKT A;  3I2W A;  4WPE A;  2RAI A;  2Q13 A;  2Q12 A;  2ELB A;  2Z0N A;  2Z0O A;  3QE6 A;  5C5B A;  3HAJ A;  3QNI A;  1I4L A;  3M3W A;  2RAJ A;  3SYV A;  2FIC A;  2EFL A;  3Q84 A;  4AVM A;  1I49 A;  2X3V A;  3CAZ A;  4AKV A;  1Y2O A;  2V0O A;  2RAK A;  1X03 A;  2Z0V A;  3LLL A;  4DCN C;  2X3W A;  4WPC A;  4FZS A;  5C5B B;  2C08 A;  3Q0K A;  2D1L A;  3QWE A;  4DYL A;  1URU A;  4I1Q A;  3ABH A;  3G9G A;  3HAI A;  3PLT A;  4NSW A;  2X3X A;  4H8S A;  3ACO A;  2EFK A; 
#chains in the Genus database with same CATH topology
 4NQI A;  2OO2 A;  4EZR A;  2OW6 A;  3B52 X;  3QE6 A;  4R5K A;  2JNS A;  1Y2O A;  3EJS A;  4EZZ A;  2N3K A;  1GN9 A;  4FZP A;  4AZ6 A;  1ZYL A;  3OK8 A;  3OWG A;  1GNL A;  2KHO A;  4WPE A;  1MJG A;  1QWU A;  3B53 X;  3QNI A;  3Q84 A;  3BUI A;  1R5E A;  4HY9 A;  2F7O A;  2YL5 A;  3D50 A;  2ND1 A;  4EZS A;  3UIT A;  3DPO A;  3BVX A;  2FYV A;  1YWM A;  4JWD A;  3ZED A;  3HAJ A;  3BUQ A;  1TQV A;  2GF4 A;  3PLT A;  1SU6 A;  4HYB A;  5TKY A;  3EJU A;  4H6I A;  3EJQ A;  2JNK A;  1I4L A;  1TQT A;  4EZT A;  3CAZ A;  4EZV A;  4IM2 A;  3BVT A;  3BUP A;  4FZS A;  1TQU A;  2WYI A;  4F01 A;  4AZB A;  2Q13 A;  4EZX A;  3C7N A;  3RV0 A;  2QKW A;  4AKV A;  2YI9 A;  2RAK A;  4DCN C;  4HR1 B;  3CVR A;  2X3W A;  3BLB A;  2PMR A;  3ABH A;  4H8S A;  2EWF A;  2PY6 A;  4B9Q A;  3HAH A;  3DDG A;  3O3O B;  1WDZ A;  3ER8 C;  2ND0 A;  3VEB A;  5KBP A;  2MI7 A;  1LQ7 A;  3RPM A;  2YIB A;  2F1B A;  2QFF A;  4R5L A;  2C08 A;  3Q0K A;  1TQW A;  2EFK A;  3DYT A;  1X04 A;  4H6H A;  1ZWW A;  3DDF A;  2RAI A;  2FIC A;  4EZN A;  1JQK A;  1DKY A;  4E3C A;  3L3O M;  4EZO A;  4F00 A;  2YIA A;  4IM3 A;  3BVV A;  3D2E A;  4AZC B;  2X3X A;  1SUF A;  4IWQ A;  2WYH A;  4HR1 A;  2Z0O A;  5C5B A;  3DPP A;  3VEA A;  3DPQ A;  3T48 A;  3D52 A;  3EJT A;  3FD9 A;  3DX0 A;  2O0I 1;  3GI7 A;  4AZI A;  2F1A A;  1OA0 A;  3LVT A;  3SYV A;  1HWW A;  2F7R A;  2V0O A;  1X03 A;  2Z0V A;  2LM0 A;  3I39 X;  3OHX M;  3EJP A;  1OAO A;  3QWE A;  4EZU A;  3D4Z A;  4M0M A;  3L3P A;  3D51 A;  3CKD A;  4BNE A;  3EJR A;  3BUB A;  1O7D B;  2F18 A;  2EFL A;  2QXL A;  4IWP A;  4AZC A;  2YLA A;  4UDX X;  1R33 A;  3D2F A;  3T46 A;  1SU7 A;  4KIK B;  1OA1 A;  5FIG A;  3T4A G;  2ALW A;  1SU8 A;  4WPC A;  1E1D A;  5C5B B;  3O3M B;  3DX3 A;  1QWN A;  1I4T A;  4R5I A;  2YKT A;  4EZP A;  2Q12 A;  2OW7 A;  2F7P A;  3QNJ A;  1I49 A;  1U00 A;  1R34 A;  3DX1 A;  3F7W A;  4NPH A;  3I04 A;  4JWE A;  1URU A;  3RV1 A;  2Z8Y A;  3QA8 A;  3VKH A;  4JWI A;  1TQS A;  1I4D A;  1W9M A;  4AZH A;  1HTY A;  2YL6 A;  4JLC A;  4JN4 A;  1DKX A;  3O3N B;  2YL8 A;  3KAW A;  4E81 A;  2EX3 B;  3CZS A;  2D4C A;  3SOG A;  4IW0 A;  4ATM A;  2OBL A;  4KIK A;  2X5C A;  2Z0N A;  2RAJ A;  1UPX A;  2RT6 A;  4AZ5 A;  2GA9 D;  2YL9 A;  4UDY X;  4I1Q A;  4NSW A;  3ACO A;  1DKZ A;  2GAF D;  3I2W A;  4FZO A;  4JWC A;  4AZG A;  2OZN B;  4FM3 A;  3LMF A;  3I01 A;  1O7D C;  2YLL A;  4AVM A;  2X3V A;  4G6Q A;  4EZQ A;  1PS3 A;  4DYL A;  4JNF A;  1E9V A;  4JNE A;  2OBM A;  4EZY A;  1E2U A;  3B51 X;  4EZW A;  3BUD A;  2F7Q A;  3KDR A;  4AZ7 A;  3CV5 A;  2YIV X;  3LLL A;  4R5G A;  3KAV A;  4R5J A;  2WIN M;  1QX1 A;  4D8J A;  3G9G A;  3HAI A;  4JL9 A;  1HXK A;  3BVW A;  5FLE X;  4IWO A;  4PO2 A;  5E84 A;  3BVU A;  4IM0 A;  3T47 A;  2YI8 A;  2ELB A;  3A98 A;  3M3W A;  3CZN A;  1GNT A;  3DX4 A;  3ERC C;  2D1L A;  3ER9 B;  2ZXQ A;  3DX2 A;  2NCZ A;  2LXY A;  3D4Y A;  3T49 A; 
#chains in the Genus database with same CATH homology
 3OK8 A;  3HAH A;  4NQI A;  1I4T A;  2D4C A;  3SOG A;  3DYT A;  4BNE A;  1X04 A;  4ATM A;  1I4D A;  1WDZ A;  1ZWW A;  2YKT A;  3I2W A;  4WPE A;  2RAI A;  2Q13 A;  2Q12 A;  2ELB A;  2Z0N A;  2Z0O A;  3QE6 A;  5C5B A;  3HAJ A;  3QNI A;  1I4L A;  3M3W A;  2RAJ A;  3SYV A;  2FIC A;  2EFL A;  3Q84 A;  4AVM A;  1I49 A;  2X3V A;  3CAZ A;  4AKV A;  1Y2O A;  2V0O A;  2RAK A;  1X03 A;  2Z0V A;  3LLL A;  4DCN C;  2X3W A;  4WPC A;  4FZS A;  5C5B B;  2C08 A;  3Q0K A;  2D1L A;  3QWE A;  4DYL A;  1URU A;  4I1Q A;  3ABH A;  3G9G A;  3HAI A;  3PLT A;  4NSW A;  2X3X A;  4H8S A;  3ACO A;  2EFK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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