2Z0NA

Crystal structure of appl1-bar domain
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
243
structure length
235
Chain Sequence
LEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLLKEYEKQEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIEDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DCC-interacting protein 13-alpha
publication title Crystal structure of APPL1-BAR domain
rcsb
source organism Homo sapiens
molecule tags Signaling protein
total genus 94
structure length 235
sequence length 243
ec nomenclature
pdb deposition date 2007-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16746 BAR_3 BAR domain of APPL family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2z0nA00
2X3WA 3QNIA 3QWEA 1URUA 3OK8A 3ACOA 2C08A 3Q0KA 1X04A 2YKTA 3M3WA 2D4CA 4I1QA 3ABHA 3QE6A 5C5BB 4NQIA 4H8SA 1I4LA 2V0OA 4NSWA 3Q84A 3I2WA 4AVMA 4BNEA 1I4TA 1Y2OA 2Z0VA 2EFKA 2RAKA 2Q13A 1ZWWA 2X3XA 3CAZA 1X03A 2EFLA 2RAIA 2RAJA 3DYTA 1I4DA 2Q12A 3HAJA 4FZSA 4DCNC 1I49A 2Z0NA 2X3VA 3SOGA 4DYLA 3HAHA 4WPEA 3PLTA 4AKVA 3SYVA 3HAIA 2ELBA 3LLLA 4WPCA 3G9GA 4ATMA 5C5BA 2Z0OA 2FICA 2D1LA 1WDZA
chains in the Genus database with same CATH superfamily
3DDFA 1SU6A 3BUIA 1I4LA 2N3KA 4EZRA 3BUBA 2EFKA 4G6QA 4AZIA 2OW7A 3O3OB 3D50A 2F7QA 3RPMA 4R5LA 3KAVA 2O0I1 3QNJA 3L3OM 3B53X 1QX1A 4AVMA 4IM2A 3D4ZA 1R33A 3VEAA 4I1QA 1R5EA 2FYVA 1OAOA 4EZZA 1I4TA 1JQKA 3DPOA 3D52A 2OO2A 2X3XA 2YL5A 1SU8A 4EZVA 2GAFD 4JWCA 2YIVX 2LM0A 2X3VA 4WPCA 5FIGA 2NCZA 4AZCB 1OA0A 3EJUA 2ND1A 3GI7A 3BVTA 3M3WA 3KDRA 2OW6A 1MJGA 1E2UA 2YIAA 2RAKA 4AZCA 4FZSA 2F7PA 2YLLA 3EJRA 3DX4A 1WDZA 4AZGA 3OK8A 2QXLA 1TQVA 4E3CA 1HXKA 1SUFA 3CVRA 3KAWA 2V0OA 4NSWA 3DPQA 3VKHA 3BVVA 1HTYA 1O7DB 1GNTA 3D2FA 3PLTA 2Z0OA 3QNIA 1URUA 2C08A 3CV5A 3T48A 2PY6A 4EZSA 4H8SA 3Q84A 3RV0A 2YL6A 2EFLA 3O3MB 1I49A 4EZWA 4EZXA 3ER8C 2F7RA 3LLLA 3EJTA 2F18A 1DKXA 2YI8A 1O7DC 2OBMA 1X04A 3EJSA 3I04A 2OBLA 2YL9A 2Z0VA 4KIKB 2PMRA 4UDXX 4IWOA 3DPPA 4HYBA 4F00A 4IWPA 4KIKA 4AZBA 4R5IA 3BVUA 2LXYA 3B51X 1DKYA 3BLBA 5C5BB 2YI9A 1W9MA 4BNEA 2F1BA 3QA8A 2EX3B 2RAIA 4JNFA 3HAJA 5E84A 3L3PA 2YIBA 4NPHA 3LVTA 2WYIA 4EZNA 5C5BA 3BUPA 4ATMA 4HR1B 4JN4A 2ZXQA 2MI7A 4EZPA 4JNEA 1ZYLA 3QE6A 4EZUA 1U00A 2WYHA 1Y2OA 3CAZA 1X03A 3DDGA 4HR1A 1I4DA 4FZOA 5TKYA 2Z8YA 4AKVA 1QWUA 4FM3A 3RV1A 4H6IA 2YL8A 1DKZA 3BUDA 1GNLA 1YWMA 4JLCA 2X3WA 3QWEA 3O3NB 3ACOA 4FZPA 3ER9B 2QFFA 2D4CA 4JWIA 3VEBA 3CKDA 3LMFA 3EJQA 2Q12A 4JL9A 3DX0A 3T49A 3HAHA 4R5JA 2JNKA 4F01A 3A98A 4IM0A 2YKTA 2JNSA 1R34A 3B52X 3ABHA 5KBPA 3DX1A 3BVXA 4AZ7A 1HWWA 4DCNC 3C7NA 4IW0A 2Z0NA 3CZSA 3DX2A 4D8JA 4IM3A 3ZEDA 3DX3A 3F7WA 2KHOA 3BVWA 1LQ7A 4EZYA 1TQSA 1E1DA 2Q13A 2OZNB 4AZ5A 4DYLA 3SOGA 3OWGA 3D51A 4WPEA 4JWDA 2GF4A 3HAIA 2ELBA 2FICA 3D2EA 3BUQA 3OHXM 4EZQA 2X5CA 5FLEX 3T4AG 1PS3A 3D4YA 1UPXA 1GN9A 3FD9A 3G9GA 3T46A 3Q0KA 2YLAA 4AZHA 1OA1A 4AZ6A 3I39X 3T47A 2WINM 4HY9A 3CZNA 2RAJA 2F7OA 1TQTA 2ND0A 1E9VA 4UDYX 2GA9D 4NQIA 2RT6A 4R5GA 3I2WA 4M0MA 4H6HA 4IWQA 3UITA 1TQUA 4JWEA 3SYVA 3ERCC 1QWNA 2D1LA 2EWFA 4PO2A 3I01A 4R5KA 4EZTA 2QKWA 2ALWA 2F1AA 1ZWWA 3DYTA 4EZOA 3EJPA 1SU7A 4E81A 1TQWA 4B9QA
chains in the Genus database with same CATH topology
2X3WA 3QNIA 3QWEA 1URUA 3OK8A 3ACOA 2C08A 3Q0KA 1X04A 2YKTA 3M3WA 2D4CA 4I1QA 3ABHA 3QE6A 5C5BB 4NQIA 4H8SA 1I4LA 2V0OA 4NSWA 3Q84A 3I2WA 4AVMA 4BNEA 1I4TA 1Y2OA 2Z0VA 2EFKA 2RAKA 2Q13A 1ZWWA 2X3XA 3CAZA 1X03A 2EFLA 2RAIA 2RAJA 3DYTA 1I4DA 2Q12A 3HAJA 4FZSA 4DCNC 1I49A 2Z0NA 2X3VA 3SOGA 4DYLA 3HAHA 4WPEA 3PLTA 4AKVA 3SYVA 3HAIA 2ELBA 3LLLA 4WPCA 3G9GA 4ATMA 5C5BA 2Z0OA 2FICA 2D1LA 1WDZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X3W A;  3QNI A;  3QWE A;  1URU A;  3OK8 A;  3ACO A;  2C08 A;  3Q0K A;  1X04 A;  2YKT A;  3M3W A;  2D4C A;  4I1Q A;  3ABH A;  3QE6 A;  5C5B B;  4NQI A;  4H8S A;  1I4L A;  2V0O A;  4NSW A;  3Q84 A;  3I2W A;  4AVM A;  4BNE A;  1I4T A;  1Y2O A;  2Z0V A;  2EFK A;  2RAK A;  2Q13 A;  1ZWW A;  2X3X A;  3CAZ A;  1X03 A;  2EFL A;  2RAI A;  2RAJ A;  3DYT A;  1I4D A;  2Q12 A;  3HAJ A;  4FZS A;  4DCN C;  1I49 A;  2Z0N A;  2X3V A;  3SOG A;  4DYL A;  3HAH A;  4WPE A;  3PLT A;  4AKV A;  3SYV A;  3HAI A;  2ELB A;  3LLL A;  4WPC A;  3G9G A;  4ATM A;  5C5B A;  2Z0O A;  2FIC A;  2D1L A;  1WDZ A; 
#chains in the Genus database with same CATH topology
 3DDF A;  1SU6 A;  3BUI A;  1I4L A;  2N3K A;  4EZR A;  3BUB A;  2EFK A;  4G6Q A;  4AZI A;  2OW7 A;  3O3O B;  3D50 A;  2F7Q A;  3RPM A;  4R5L A;  3KAV A;  2O0I 1;  3QNJ A;  3L3O M;  3B53 X;  1QX1 A;  4AVM A;  4IM2 A;  3D4Z A;  1R33 A;  3VEA A;  4I1Q A;  1R5E A;  2FYV A;  1OAO A;  4EZZ A;  1I4T A;  1JQK A;  3DPO A;  3D52 A;  2OO2 A;  2X3X A;  2YL5 A;  1SU8 A;  4EZV A;  2GAF D;  4JWC A;  2YIV X;  2LM0 A;  2X3V A;  4WPC A;  5FIG A;  2NCZ A;  4AZC B;  1OA0 A;  3EJU A;  2ND1 A;  3GI7 A;  3BVT A;  3M3W A;  3KDR A;  2OW6 A;  1MJG A;  1E2U A;  2YIA A;  2RAK A;  4AZC A;  4FZS A;  2F7P A;  2YLL A;  3EJR A;  3DX4 A;  1WDZ A;  4AZG A;  3OK8 A;  2QXL A;  1TQV A;  4E3C A;  1HXK A;  1SUF A;  3CVR A;  3KAW A;  2V0O A;  4NSW A;  3DPQ A;  3VKH A;  3BVV A;  1HTY A;  1O7D B;  1GNT A;  3D2F A;  3PLT A;  2Z0O A;  3QNI A;  1URU A;  2C08 A;  3CV5 A;  3T48 A;  2PY6 A;  4EZS A;  4H8S A;  3Q84 A;  3RV0 A;  2YL6 A;  2EFL A;  3O3M B;  1I49 A;  4EZW A;  4EZX A;  3ER8 C;  2F7R A;  3LLL A;  3EJT A;  2F18 A;  1DKX A;  2YI8 A;  1O7D C;  2OBM A;  1X04 A;  3EJS A;  3I04 A;  2OBL A;  2YL9 A;  2Z0V A;  4KIK B;  2PMR A;  4UDX X;  4IWO A;  3DPP A;  4HYB A;  4F00 A;  4IWP A;  4KIK A;  4AZB A;  4R5I A;  3BVU A;  2LXY A;  3B51 X;  1DKY A;  3BLB A;  5C5B B;  2YI9 A;  1W9M A;  4BNE A;  2F1B A;  3QA8 A;  2EX3 B;  2RAI A;  4JNF A;  3HAJ A;  5E84 A;  3L3P A;  2YIB A;  4NPH A;  3LVT A;  2WYI A;  4EZN A;  5C5B A;  3BUP A;  4ATM A;  4HR1 B;  4JN4 A;  2ZXQ A;  2MI7 A;  4EZP A;  4JNE A;  1ZYL A;  3QE6 A;  4EZU A;  1U00 A;  2WYH A;  1Y2O A;  3CAZ A;  1X03 A;  3DDG A;  4HR1 A;  1I4D A;  4FZO A;  5TKY A;  2Z8Y A;  4AKV A;  1QWU A;  4FM3 A;  3RV1 A;  4H6I A;  2YL8 A;  1DKZ A;  3BUD A;  1GNL A;  1YWM A;  4JLC A;  2X3W A;  3QWE A;  3O3N B;  3ACO A;  4FZP A;  3ER9 B;  2QFF A;  2D4C A;  4JWI A;  3VEB A;  3CKD A;  3LMF A;  3EJQ A;  2Q12 A;  4JL9 A;  3DX0 A;  3T49 A;  3HAH A;  4R5J A;  2JNK A;  4F01 A;  3A98 A;  4IM0 A;  2YKT A;  2JNS A;  1R34 A;  3B52 X;  3ABH A;  5KBP A;  3DX1 A;  3BVX A;  4AZ7 A;  1HWW A;  4DCN C;  3C7N A;  4IW0 A;  2Z0N A;  3CZS A;  3DX2 A;  4D8J A;  4IM3 A;  3ZED A;  3DX3 A;  3F7W A;  2KHO A;  3BVW A;  1LQ7 A;  4EZY A;  1TQS A;  1E1D A;  2Q13 A;  2OZN B;  4AZ5 A;  4DYL A;  3SOG A;  3OWG A;  3D51 A;  4WPE A;  4JWD A;  2GF4 A;  3HAI A;  2ELB A;  2FIC A;  3D2E A;  3BUQ A;  3OHX M;  4EZQ A;  2X5C A;  5FLE X;  3T4A G;  1PS3 A;  3D4Y A;  1UPX A;  1GN9 A;  3FD9 A;  3G9G A;  3T46 A;  3Q0K A;  2YLA A;  4AZH A;  1OA1 A;  4AZ6 A;  3I39 X;  3T47 A;  2WIN M;  4HY9 A;  3CZN A;  2RAJ A;  2F7O A;  1TQT A;  2ND0 A;  1E9V A;  4UDY X;  2GA9 D;  4NQI A;  2RT6 A;  4R5G A;  3I2W A;  4M0M A;  4H6H A;  4IWQ A;  3UIT A;  1TQU A;  4JWE A;  3SYV A;  3ERC C;  1QWN A;  2D1L A;  2EWF A;  4PO2 A;  3I01 A;  4R5K A;  4EZT A;  2QKW A;  2ALW A;  2F1A A;  1ZWW A;  3DYT A;  4EZO A;  3EJP A;  1SU7 A;  4E81 A;  1TQW A;  4B9Q A; 
#chains in the Genus database with same CATH homology
 2X3W A;  3QNI A;  3QWE A;  1URU A;  3OK8 A;  3ACO A;  2C08 A;  3Q0K A;  1X04 A;  2YKT A;  3M3W A;  2D4C A;  4I1Q A;  3ABH A;  3QE6 A;  5C5B B;  4NQI A;  4H8S A;  1I4L A;  2V0O A;  4NSW A;  3Q84 A;  3I2W A;  4AVM A;  4BNE A;  1I4T A;  1Y2O A;  2Z0V A;  2EFK A;  2RAK A;  2Q13 A;  1ZWW A;  2X3X A;  3CAZ A;  1X03 A;  2EFL A;  2RAI A;  2RAJ A;  3DYT A;  1I4D A;  2Q12 A;  3HAJ A;  4FZS A;  4DCN C;  1I49 A;  2Z0N A;  2X3V A;  3SOG A;  4DYL A;  3HAH A;  4WPE A;  3PLT A;  4AKV A;  3SYV A;  3HAI A;  2ELB A;  3LLL A;  4WPC A;  3G9G A;  4ATM A;  5C5B A;  2Z0O A;  2FIC A;  2D1L A;  1WDZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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