2Z0NA

Crystal structure of appl1-bar domain
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
243
structure length
235
Chain Sequence
LEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLLKEYEKQEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIEDLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DCC-interacting protein 13-alpha
publication title Crystal structure of APPL1-BAR domain
rcsb
source organism Homo sapiens
molecule tags Signaling protein
total genus 94
structure length 235
sequence length 243
ec nomenclature
pdb deposition date 2007-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16746 BAR_3 BAR domain of APPL family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2z0nA00
4H8SA 3CAZA 2V0OA 3ACOA 3Q84A 3QWEA 2RAKA 3M3WA 2RAIA 2Q12A 1I4DA 5C5BA 2Z0NA 3LLLA 2EFLA 2X3WA 4AVMA 4NQIA 3HAJA 2X3XA 2EFKA 2ELBA 4DCNC 1I4TA 4NSWA 2YKTA 3Q0KA 4FZSA 2Z0OA 3G9GA 3OK8A 4DYLA 2FICA 2Q13A 5C5BB 4AKVA 1WDZA 4WPEA 1Y2OA 2Z0VA 3ABHA 3HAIA 2RAJA 4WPCA 2D1LA 4I1QA 1X03A 3SYVA 1I4LA 1URUA 1X04A 2X3VA 3QE6A 3SOGA 3PLTA 3I2WA 1ZWWA 3HAHA 4ATMA 1I49A 2C08A 2D4CA 3QNIA 3DYTA 4BNEA
chains in the Genus database with same CATH superfamily
2ND0A 4JWDA 1QX1A 2NCZA 3VEAA 1QWUA 2EWFA 2ELBA 1OAOA 2OO2A 3CZNA 3O3OB 4JWCA 2Z0VA 4PO2A 5KBPA 2RAJA 4EZVA 4R5LA 2RT6A 1ZYLA 4G6QA 3CV5A 5TKYA 1HTYA 2YIVX 3DYTA 2V0OA 3ACOA 3BVVA 3T49A 2YLAA 4NSWA 3BUDA 4FZSA 3D50A 4EZQA 1WDZA 4WPCA 1PS3A 4AZ6A 1X03A 4E3CA 4R5KA 3BVUA 1SU6A 1R33A 3L3OM 4UDYX 2EFLA 2ND1A 4EZSA 3D51A 1SU8A 4JNFA 4AKVA 1Y2OA 3I01A 3BVXA 2YLLA 4JWEA 3BVTA 3BVWA 1JQKA 1E1DA 3T4AG 3DX1A 3QNJA 1E9VA 3BLBA 4DCNC 2EFKA 2WYIA 2PMRA 3EJUA 4KIKA 1GN9A 4DYLA 1TQWA 3A98A 3T48A 4I1QA 1I4LA 2JNSA 2YL5A 5E84A 2F1BA 4EZUA 4AZ5A 2RAKA 2YI9A 2RAIA 4AVMA 2QXLA 3EJQA 2OZNB 3LVTA 3B51X 4JLCA 2FYVA 4R5GA 3D2EA 4R5IA 2WINM 4IWQA 3B53X 3ZEDA 1U00A 4IM2A 4HYBA 1DKZA 3ER9B 4F00A 4AZHA 1X04A 4F01A 2GF4A 1I49A 4EZPA 2OW7A 4EZOA 4UDXX 2ALWA 1HWWA 3DDFA 5C5BA 3DPOA 3DPQA 4AZCA 4AZGA 1LQ7A 4AZIA 3PLTA 4ATMA 2D4CA 3ERCC 3DX0A 3KAVA 2YI8A 4BNEA 3M3WA 2GA9D 2Z0NA 4IM0A 2QFFA 3KDRA 4WPEA 1HXKA 2YIBA 1SU7A 4HY9A 1URUA 3LMFA 3D2FA 3QNIA 3BUBA 3UITA 3VKHA 2F7PA 5FLEX 1I4DA 3KAWA 3LLLA 4IWPA 4NQIA 3CVRA 3HAJA 4AZ7A 3ER8C 3G9GA 1GNLA 1R5EA 2FICA 3D4ZA 2OW6A 3EJTA 2QKWA 2PY6A 2KHOA 2X3WA 3GI7A 2YIAA 1TQVA 4HR1A 2MI7A 3Q0KA 2O0I1 1DKXA 1W9MA 2F7OA 3O3MB 2D1LA 1TQTA 1QWNA 2LXYA 4M0MA 4FZOA 4IW0A 3Q84A 1TQSA 4NPHA 1E2UA 3DX2A 2F7RA 2F1AA 1MJGA 1OA1A 3ABHA 4EZYA 3QA8A 3SYVA 4JWIA 3L3PA 2F18A 3BUPA 3EJPA 1UPXA 4EZTA 2OBMA 2YKTA 3O3NB 3RPMA 3HAIA 3CZSA 2X3VA 3T46A 3SOGA 3CAZA 3QWEA 2F7QA 3VEBA 3BUQA 3F7WA 1OA0A 2Q12A 3EJSA 1O7DB 3OWGA 3D52A 1I4TA 3DX3A 2Z0OA 4IM3A 1SUFA 4EZXA 5C5BB 3DX4A 2WYHA 1O7DC 3OHXM 4AZCB 4EZWA 5FIGA 2JNKA 3I2WA 2GAFD 4FM3A 2ZXQA 3I04A 4JL9A 3EJRA 3T47A 4EZRA 3BUIA 2LM0A 2OBLA 4H6HA 4EZZA 4R5JA 1DKYA 3QE6A 2X5CA 4D8JA 4H6IA 3RV1A 4H8SA 1R34A 4B9QA 3B52X 2YL6A 4AZBA 2Z8YA 2Q13A 3RV0A 3FD9A 2YL9A 1TQUA 2YL8A 4KIKB 4EZNA 3HAHA 4JN4A 2C08A 2EX3B 3D4YA 4E81A 4JNEA 3CKDA 1GNTA 4FZPA 2X3XA 3C7NA 4IWOA 3OK8A 3I39X 3DPPA 4HR1B 3DDGA 2N3KA 1ZWWA 1YWMA
chains in the Genus database with same CATH topology
4H8SA 3CAZA 2V0OA 3ACOA 3Q84A 3QWEA 2RAKA 3M3WA 2RAIA 2Q12A 1I4DA 5C5BA 2Z0NA 3LLLA 2EFLA 2X3WA 4AVMA 4NQIA 3HAJA 2X3XA 2EFKA 2ELBA 4DCNC 1I4TA 4NSWA 2YKTA 3Q0KA 4FZSA 2Z0OA 3G9GA 3OK8A 4DYLA 2FICA 2Q13A 5C5BB 4AKVA 1WDZA 4WPEA 1Y2OA 2Z0VA 3ABHA 3HAIA 2RAJA 4WPCA 2D1LA 4I1QA 1X03A 3SYVA 1I4LA 1URUA 1X04A 2X3VA 3QE6A 3SOGA 3PLTA 3I2WA 1ZWWA 3HAHA 4ATMA 1I49A 2C08A 2D4CA 3QNIA 3DYTA 4BNEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H8S A;  3CAZ A;  2V0O A;  3ACO A;  3Q84 A;  3QWE A;  2RAK A;  3M3W A;  2RAI A;  2Q12 A;  1I4D A;  5C5B A;  2Z0N A;  3LLL A;  2EFL A;  2X3W A;  4AVM A;  4NQI A;  3HAJ A;  2X3X A;  2EFK A;  2ELB A;  4DCN C;  1I4T A;  4NSW A;  2YKT A;  3Q0K A;  4FZS A;  2Z0O A;  3G9G A;  3OK8 A;  4DYL A;  2FIC A;  2Q13 A;  5C5B B;  4AKV A;  1WDZ A;  4WPE A;  1Y2O A;  2Z0V A;  3ABH A;  3HAI A;  2RAJ A;  4WPC A;  2D1L A;  4I1Q A;  1X03 A;  3SYV A;  1I4L A;  1URU A;  1X04 A;  2X3V A;  3QE6 A;  3SOG A;  3PLT A;  3I2W A;  1ZWW A;  3HAH A;  4ATM A;  1I49 A;  2C08 A;  2D4C A;  3QNI A;  3DYT A;  4BNE A; 
#chains in the Genus database with same CATH topology
 2ND0 A;  4JWD A;  1QX1 A;  2NCZ A;  3VEA A;  1QWU A;  2EWF A;  2ELB A;  1OAO A;  2OO2 A;  3CZN A;  3O3O B;  4JWC A;  2Z0V A;  4PO2 A;  5KBP A;  2RAJ A;  4EZV A;  4R5L A;  2RT6 A;  1ZYL A;  4G6Q A;  3CV5 A;  5TKY A;  1HTY A;  2YIV X;  3DYT A;  2V0O A;  3ACO A;  3BVV A;  3T49 A;  2YLA A;  4NSW A;  3BUD A;  4FZS A;  3D50 A;  4EZQ A;  1WDZ A;  4WPC A;  1PS3 A;  4AZ6 A;  1X03 A;  4E3C A;  4R5K A;  3BVU A;  1SU6 A;  1R33 A;  3L3O M;  4UDY X;  2EFL A;  2ND1 A;  4EZS A;  3D51 A;  1SU8 A;  4JNF A;  4AKV A;  1Y2O A;  3I01 A;  3BVX A;  2YLL A;  4JWE A;  3BVT A;  3BVW A;  1JQK A;  1E1D A;  3T4A G;  3DX1 A;  3QNJ A;  1E9V A;  3BLB A;  4DCN C;  2EFK A;  2WYI A;  2PMR A;  3EJU A;  4KIK A;  1GN9 A;  4DYL A;  1TQW A;  3A98 A;  3T48 A;  4I1Q A;  1I4L A;  2JNS A;  2YL5 A;  5E84 A;  2F1B A;  4EZU A;  4AZ5 A;  2RAK A;  2YI9 A;  2RAI A;  4AVM A;  2QXL A;  3EJQ A;  2OZN B;  3LVT A;  3B51 X;  4JLC A;  2FYV A;  4R5G A;  3D2E A;  4R5I A;  2WIN M;  4IWQ A;  3B53 X;  3ZED A;  1U00 A;  4IM2 A;  4HYB A;  1DKZ A;  3ER9 B;  4F00 A;  4AZH A;  1X04 A;  4F01 A;  2GF4 A;  1I49 A;  4EZP A;  2OW7 A;  4EZO A;  4UDX X;  2ALW A;  1HWW A;  3DDF A;  5C5B A;  3DPO A;  3DPQ A;  4AZC A;  4AZG A;  1LQ7 A;  4AZI A;  3PLT A;  4ATM A;  2D4C A;  3ERC C;  3DX0 A;  3KAV A;  2YI8 A;  4BNE A;  3M3W A;  2GA9 D;  2Z0N A;  4IM0 A;  2QFF A;  3KDR A;  4WPE A;  1HXK A;  2YIB A;  1SU7 A;  4HY9 A;  1URU A;  3LMF A;  3D2F A;  3QNI A;  3BUB A;  3UIT A;  3VKH A;  2F7P A;  5FLE X;  1I4D A;  3KAW A;  3LLL A;  4IWP A;  4NQI A;  3CVR A;  3HAJ A;  4AZ7 A;  3ER8 C;  3G9G A;  1GNL A;  1R5E A;  2FIC A;  3D4Z A;  2OW6 A;  3EJT A;  2QKW A;  2PY6 A;  2KHO A;  2X3W A;  3GI7 A;  2YIA A;  1TQV A;  4HR1 A;  2MI7 A;  3Q0K A;  2O0I 1;  1DKX A;  1W9M A;  2F7O A;  3O3M B;  2D1L A;  1TQT A;  1QWN A;  2LXY A;  4M0M A;  4FZO A;  4IW0 A;  3Q84 A;  1TQS A;  4NPH A;  1E2U A;  3DX2 A;  2F7R A;  2F1A A;  1MJG A;  1OA1 A;  3ABH A;  4EZY A;  3QA8 A;  3SYV A;  4JWI A;  3L3P A;  2F18 A;  3BUP A;  3EJP A;  1UPX A;  4EZT A;  2OBM A;  2YKT A;  3O3N B;  3RPM A;  3HAI A;  3CZS A;  2X3V A;  3T46 A;  3SOG A;  3CAZ A;  3QWE A;  2F7Q A;  3VEB A;  3BUQ A;  3F7W A;  1OA0 A;  2Q12 A;  3EJS A;  1O7D B;  3OWG A;  3D52 A;  1I4T A;  3DX3 A;  2Z0O A;  4IM3 A;  1SUF A;  4EZX A;  5C5B B;  3DX4 A;  2WYH A;  1O7D C;  3OHX M;  4AZC B;  4EZW A;  5FIG A;  2JNK A;  3I2W A;  2GAF D;  4FM3 A;  2ZXQ A;  3I04 A;  4JL9 A;  3EJR A;  3T47 A;  4EZR A;  3BUI A;  2LM0 A;  2OBL A;  4H6H A;  4EZZ A;  4R5J A;  1DKY A;  3QE6 A;  2X5C A;  4D8J A;  4H6I A;  3RV1 A;  4H8S A;  1R34 A;  4B9Q A;  3B52 X;  2YL6 A;  4AZB A;  2Z8Y A;  2Q13 A;  3RV0 A;  3FD9 A;  2YL9 A;  1TQU A;  2YL8 A;  4KIK B;  4EZN A;  3HAH A;  4JN4 A;  2C08 A;  2EX3 B;  3D4Y A;  4E81 A;  4JNE A;  3CKD A;  1GNT A;  4FZP A;  2X3X A;  3C7N A;  4IWO A;  3OK8 A;  3I39 X;  3DPP A;  4HR1 B;  3DDG A;  2N3K A;  1ZWW A;  1YWM A; 
#chains in the Genus database with same CATH homology
 4H8S A;  3CAZ A;  2V0O A;  3ACO A;  3Q84 A;  3QWE A;  2RAK A;  3M3W A;  2RAI A;  2Q12 A;  1I4D A;  5C5B A;  2Z0N A;  3LLL A;  2EFL A;  2X3W A;  4AVM A;  4NQI A;  3HAJ A;  2X3X A;  2EFK A;  2ELB A;  4DCN C;  1I4T A;  4NSW A;  2YKT A;  3Q0K A;  4FZS A;  2Z0O A;  3G9G A;  3OK8 A;  4DYL A;  2FIC A;  2Q13 A;  5C5B B;  4AKV A;  1WDZ A;  4WPE A;  1Y2O A;  2Z0V A;  3ABH A;  3HAI A;  2RAJ A;  4WPC A;  2D1L A;  4I1Q A;  1X03 A;  3SYV A;  1I4L A;  1URU A;  1X04 A;  2X3V A;  3QE6 A;  3SOG A;  3PLT A;  3I2W A;  1ZWW A;  3HAH A;  4ATM A;  1I49 A;  2C08 A;  2D4C A;  3QNI A;  3DYT A;  4BNE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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