3Q0KA

Crystal structure of human pacsin 2 f-bar
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
289
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKAPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQEEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Endocytosis
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
publication title Crystal structure of human PACSIN 2 F-BAR domain
rcsb
source organism Homo sapiens
total genus 113
structure length 287
sequence length 289
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3q0kA01
2Z0NA 4WPCA 2RAIA 4AVMA 4NQIA 2D4CA 3SYVA 3LLLA 5C5BB 4DCNC 2YKTA 1I49A 4FZSA 2X3VA 3I2WA 4DYLA 4NSWA 1WDZA 3QE6A 5C5BA 2Z0VA 2C08A 1URUA 1I4LA 4H8SA 2EFKA 1I4DA 3ABHA 3CAZA 1Y2OA 3HAIA 2D1LA 3PLTA 3G9GA 4ATMA 3OK8A 1X03A 4I1QA 4BNEA 3HAJA 2Z0OA 3M3WA 4AKVA 2EFLA 3HAHA 2X3WA 1X04A 2RAJA 2V0OA 2RAKA 1I4TA 1ZWWA 2Q12A 2ELBA 2Q13A 3Q84A 4WPEA 3Q0KA 3QWEA 2X3XA 3DYTA 3ACOA 3QNIA 2FICA 3SOGA
chains in the Genus database with same CATH superfamily
4AZHA 1MJGA 2QXLA 1R5EA 2QFFA 1WDZA 2Z0VA 3I39X 2EFKA 4EZSA 2YIBA 2EFLA 1GN9A 1I4TA 4B9QA 3QWEA 2YL8A 3I04A 1YWMA 4AZ5A 4E3CA 3EJQA 4HY9A 2Z8YA 3BVUA 4PO2A 1E2UA 3DPQA 4R5GA 3BVXA 4FZOA 3T49A 3D50A 4EZZA 3KAWA 4R5LA 2X5CA 3QNIA 4HR1A 4G6QA 1TQVA 1URUA 2LM0A 3CAZA 4ATMA 2YLAA 4AKVA 3D4ZA 3BLBA 2GA9D 3RV1A 3CV5A 3BUIA 2OW6A 4HR1B 1UPXA 1E9VA 3LLLA 4DCNC 3I01A 4DYLA 5C5BA 2ZXQA 3DDGA 2F18A 3L3OM 2YL5A 3D2FA 3HAJA 1HXKA 4JNFA 4FM3A 3OHXM 2O0I1 4JLCA 1DKYA 5C5BB 2YI9A 1SU6A 3D4YA 2F7OA 2YIVX 3PLTA 3ER8C 2EWFA 3T4AG 1U00A 2F1BA 3BVVA 1SU7A 1ZWWA 3DPPA 2EX3B 3EJTA 4UDYX 4D8JA 4H6IA 5FLEX 1DKZA 1TQWA 2WYIA 2D1LA 4F01A 1TQTA 2GAFD 4JNEA 4EZUA 2RAJA 4IWPA 2JNKA 1O7DB 2ND0A 4EZOA 3ACOA 2Z0NA 3DX1A 2F7RA 4NSWA 2PY6A 2LXYA 3ABHA 2OZNB 1X03A 3OK8A 1E1DA 4EZYA 3EJPA 3EJRA 2PMRA 3VEAA 3SOGA 3CZSA 1QWUA 3T47A 1I49A 2YIAA 4EZWA 2MI7A 3D52A 3CKDA 1I4LA 2WYHA 4FZPA 4JWIA 2ND1A 4EZPA 3VEBA 1X04A 4KIKA 4IM3A 2OW7A 1O7DC 2RAIA 4NQIA 3DPOA 1OA0A 2F7PA 2X3VA 4JWEA 4EZNA 1HWWA 1TQSA 4NPHA 3OWGA 5KBPA 4BNEA 1HTYA 4KIKB 5FIGA 3HAHA 2WINM 2F7QA 1PS3A 4R5KA 2ELBA 3DDFA 3DX3A 1R33A 4H6HA 4WPCA 3T46A 1QX1A 1OA1A 4JWCA 2YL9A 3BUPA 1I4DA 3B51X 4JN4A 4JL9A 3DX0A 4UDXX 3RPMA 3BVWA 2Q13A 2YL6A 2FICA 2N3KA 3VKHA 3SYVA 4IM0A 4FZSA 2OBLA 4IW0A 3CVRA 4EZTA 4R5JA 3HAIA 1JQKA 2QKWA 3DX4A 2RAKA 1TQUA 5TKYA 4AZBA 3RV0A 4AVMA 1QWNA 4EZXA 3BVTA 3B52X 2F1AA 2JNSA 1LQ7A 3ZEDA 3QE6A 3LMFA 1SUFA 1GNLA 2KHOA 1ZYLA 3ERCC 4AZCA 3BUDA 3Q84A 4IWOA 3ER9B 3QNJA 2OBMA 4M0MA 1GNTA 2D4CA 4IM2A 3GI7A 3KAVA 4H8SA 4AZIA 4EZVA 3EJSA 3EJUA 5E84A 4AZCB 2YI8A 1SU8A 2X3WA 4EZRA 1W9MA 3UITA 2X3XA 2RT6A 2C08A 2OO2A 1R34A 1Y2OA 3DX2A 4I1QA 3A98A 2Z0OA 3FD9A 3M3WA 3D51A 2FYVA 3LVTA 4AZ6A 4AZGA 3O3NB 4E81A 1DKXA 3I2WA 2GF4A 3L3PA 3O3OB 3B53X 3G9GA 4JWDA 3BUQA 4IWQA 3CZNA 2V0OA 1OAOA 2ALWA 4WPEA 3F7WA 3DYTA 4R5IA 2YKTA 4AZ7A 3D2EA 4HYBA 2NCZA 4F00A 3QA8A 2YLLA 3BUBA 3C7NA 3KDRA 2Q12A 3O3MB 3T48A 4EZQA 3Q0KA
chains in the Genus database with same CATH topology
2Z0NA 4WPCA 2RAIA 4AVMA 4NQIA 2D4CA 3SYVA 3LLLA 5C5BB 4DCNC 2YKTA 1I49A 4FZSA 2X3VA 3I2WA 4DYLA 4NSWA 1WDZA 3QE6A 5C5BA 2Z0VA 2C08A 1URUA 1I4LA 4H8SA 2EFKA 1I4DA 3ABHA 3CAZA 1Y2OA 3HAIA 2D1LA 3PLTA 3G9GA 4ATMA 3OK8A 1X03A 4I1QA 4BNEA 3HAJA 2Z0OA 3M3WA 4AKVA 2EFLA 3HAHA 2X3WA 1X04A 2RAJA 2V0OA 2RAKA 1I4TA 1ZWWA 2Q12A 2ELBA 2Q13A 3Q84A 4WPEA 3Q0KA 3QWEA 2X3XA 3DYTA 3ACOA 3QNIA 2FICA 3SOGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z0N A;  4WPC A;  2RAI A;  4AVM A;  4NQI A;  2D4C A;  3SYV A;  3LLL A;  5C5B B;  4DCN C;  2YKT A;  1I49 A;  4FZS A;  2X3V A;  3I2W A;  4DYL A;  4NSW A;  1WDZ A;  3QE6 A;  5C5B A;  2Z0V A;  2C08 A;  1URU A;  1I4L A;  4H8S A;  2EFK A;  1I4D A;  3ABH A;  3CAZ A;  1Y2O A;  3HAI A;  2D1L A;  3PLT A;  3G9G A;  4ATM A;  3OK8 A;  1X03 A;  4I1Q A;  4BNE A;  3HAJ A;  2Z0O A;  3M3W A;  4AKV A;  2EFL A;  3HAH A;  2X3W A;  1X04 A;  2RAJ A;  2V0O A;  2RAK A;  1I4T A;  1ZWW A;  2Q12 A;  2ELB A;  2Q13 A;  3Q84 A;  4WPE A;  3Q0K A;  3QWE A;  2X3X A;  3DYT A;  3ACO A;  3QNI A;  2FIC A;  3SOG A; 
#chains in the Genus database with same CATH topology
 4AZH A;  1MJG A;  2QXL A;  1R5E A;  2QFF A;  1WDZ A;  2Z0V A;  3I39 X;  2EFK A;  4EZS A;  2YIB A;  2EFL A;  1GN9 A;  1I4T A;  4B9Q A;  3QWE A;  2YL8 A;  3I04 A;  1YWM A;  4AZ5 A;  4E3C A;  3EJQ A;  4HY9 A;  2Z8Y A;  3BVU A;  4PO2 A;  1E2U A;  3DPQ A;  4R5G A;  3BVX A;  4FZO A;  3T49 A;  3D50 A;  4EZZ A;  3KAW A;  4R5L A;  2X5C A;  3QNI A;  4HR1 A;  4G6Q A;  1TQV A;  1URU A;  2LM0 A;  3CAZ A;  4ATM A;  2YLA A;  4AKV A;  3D4Z A;  3BLB A;  2GA9 D;  3RV1 A;  3CV5 A;  3BUI A;  2OW6 A;  4HR1 B;  1UPX A;  1E9V A;  3LLL A;  4DCN C;  3I01 A;  4DYL A;  5C5B A;  2ZXQ A;  3DDG A;  2F18 A;  3L3O M;  2YL5 A;  3D2F A;  3HAJ A;  1HXK A;  4JNF A;  4FM3 A;  3OHX M;  2O0I 1;  4JLC A;  1DKY A;  5C5B B;  2YI9 A;  1SU6 A;  3D4Y A;  2F7O A;  2YIV X;  3PLT A;  3ER8 C;  2EWF A;  3T4A G;  1U00 A;  2F1B A;  3BVV A;  1SU7 A;  1ZWW A;  3DPP A;  2EX3 B;  3EJT A;  4UDY X;  4D8J A;  4H6I A;  5FLE X;  1DKZ A;  1TQW A;  2WYI A;  2D1L A;  4F01 A;  1TQT A;  2GAF D;  4JNE A;  4EZU A;  2RAJ A;  4IWP A;  2JNK A;  1O7D B;  2ND0 A;  4EZO A;  3ACO A;  2Z0N A;  3DX1 A;  2F7R A;  4NSW A;  2PY6 A;  2LXY A;  3ABH A;  2OZN B;  1X03 A;  3OK8 A;  1E1D A;  4EZY A;  3EJP A;  3EJR A;  2PMR A;  3VEA A;  3SOG A;  3CZS A;  1QWU A;  3T47 A;  1I49 A;  2YIA A;  4EZW A;  2MI7 A;  3D52 A;  3CKD A;  1I4L A;  2WYH A;  4FZP A;  4JWI A;  2ND1 A;  4EZP A;  3VEB A;  1X04 A;  4KIK A;  4IM3 A;  2OW7 A;  1O7D C;  2RAI A;  4NQI A;  3DPO A;  1OA0 A;  2F7P A;  2X3V A;  4JWE A;  4EZN A;  1HWW A;  1TQS A;  4NPH A;  3OWG A;  5KBP A;  4BNE A;  1HTY A;  4KIK B;  5FIG A;  3HAH A;  2WIN M;  2F7Q A;  1PS3 A;  4R5K A;  2ELB A;  3DDF A;  3DX3 A;  1R33 A;  4H6H A;  4WPC A;  3T46 A;  1QX1 A;  1OA1 A;  4JWC A;  2YL9 A;  3BUP A;  1I4D A;  3B51 X;  4JN4 A;  4JL9 A;  3DX0 A;  4UDX X;  3RPM A;  3BVW A;  2Q13 A;  2YL6 A;  2FIC A;  2N3K A;  3VKH A;  3SYV A;  4IM0 A;  4FZS A;  2OBL A;  4IW0 A;  3CVR A;  4EZT A;  4R5J A;  3HAI A;  1JQK A;  2QKW A;  3DX4 A;  2RAK A;  1TQU A;  5TKY A;  4AZB A;  3RV0 A;  4AVM A;  1QWN A;  4EZX A;  3BVT A;  3B52 X;  2F1A A;  2JNS A;  1LQ7 A;  3ZED A;  3QE6 A;  3LMF A;  1SUF A;  1GNL A;  2KHO A;  1ZYL A;  3ERC C;  4AZC A;  3BUD A;  3Q84 A;  4IWO A;  3ER9 B;  3QNJ A;  2OBM A;  4M0M A;  1GNT A;  2D4C A;  4IM2 A;  3GI7 A;  3KAV A;  4H8S A;  4AZI A;  4EZV A;  3EJS A;  3EJU A;  5E84 A;  4AZC B;  2YI8 A;  1SU8 A;  2X3W A;  4EZR A;  1W9M A;  3UIT A;  2X3X A;  2RT6 A;  2C08 A;  2OO2 A;  1R34 A;  1Y2O A;  3DX2 A;  4I1Q A;  3A98 A;  2Z0O A;  3FD9 A;  3M3W A;  3D51 A;  2FYV A;  3LVT A;  4AZ6 A;  4AZG A;  3O3N B;  4E81 A;  1DKX A;  3I2W A;  2GF4 A;  3L3P A;  3O3O B;  3B53 X;  3G9G A;  4JWD A;  3BUQ A;  4IWQ A;  3CZN A;  2V0O A;  1OAO A;  2ALW A;  4WPE A;  3F7W A;  3DYT A;  4R5I A;  2YKT A;  4AZ7 A;  3D2E A;  4HYB A;  2NCZ A;  4F00 A;  3QA8 A;  2YLL A;  3BUB A;  3C7N A;  3KDR A;  2Q12 A;  3O3M B;  3T48 A;  4EZQ A;  3Q0K A; 
#chains in the Genus database with same CATH homology
 2Z0N A;  4WPC A;  2RAI A;  4AVM A;  4NQI A;  2D4C A;  3SYV A;  3LLL A;  5C5B B;  4DCN C;  2YKT A;  1I49 A;  4FZS A;  2X3V A;  3I2W A;  4DYL A;  4NSW A;  1WDZ A;  3QE6 A;  5C5B A;  2Z0V A;  2C08 A;  1URU A;  1I4L A;  4H8S A;  2EFK A;  1I4D A;  3ABH A;  3CAZ A;  1Y2O A;  3HAI A;  2D1L A;  3PLT A;  3G9G A;  4ATM A;  3OK8 A;  1X03 A;  4I1Q A;  4BNE A;  3HAJ A;  2Z0O A;  3M3W A;  4AKV A;  2EFL A;  3HAH A;  2X3W A;  1X04 A;  2RAJ A;  2V0O A;  2RAK A;  1I4T A;  1ZWW A;  2Q12 A;  2ELB A;  2Q13 A;  3Q84 A;  4WPE A;  3Q0K A;  3QWE A;  2X3X A;  3DYT A;  3ACO A;  3QNI A;  2FIC A;  3SOG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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