3Q0KA

Crystal structure of human pacsin 2 f-bar
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
289
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKAPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQEEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human PACSIN 2 F-BAR domain
rcsb
source organism Homo sapiens
molecule tags Endocytosis
molecule keywords Protein kinase C and casein kinase substrate in neurons prot
total genus 113
structure length 287
sequence length 289
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3q0kA01
3ABHA 1WDZA 4DCNC 5C5BA 2ELBA 2FICA 3SOGA 2X3VA 2RAKA 3HAIA 2Q13A 3QE6A 3G9GA 2RAJA 3PLTA 2V0OA 3I2WA 3ACOA 1I4TA 5C5BB 4BNEA 1I49A 1Y2OA 3LLLA 2Z0VA 3M3WA 4NSWA 4WPCA 4ATMA 4WPEA 4NQIA 3CAZA 2Q12A 2C08A 1I4LA 4H8SA 4FZSA 1X04A 3QNIA 2RAIA 3DYTA 2EFLA 3HAHA 3Q0KA 2EFKA 4DYLA 1X03A 4AVMA 3SYVA 3OK8A 4I1QA 3Q84A 3HAJA 2YKTA 1ZWWA 2X3WA 1I4DA 3QWEA 1URUA 2D1LA 2X3XA 4AKVA 2D4CA 2Z0NA 2Z0OA
chains in the Genus database with same CATH superfamily
1OA1A 1WDZA 1YWMA 1ZYLA 1TQWA 3BUDA 1R33A 3KAVA 2LM0A 3G9GA 3D52A 2OO2A 2RAJA 4R5IA 2NCZA 2PMRA 3FD9A 2ND0A 2F7OA 1TQSA 2YLLA 4AZ6A 2F7RA 4EZPA 3KDRA 2EWFA 2O0I1 3BUQA 4AZIA 3L3PA 4R5KA 3CAZA 4HR1A 4JN4A 3DX3A 3QA8A 2C08A 4M0MA 4FZSA 1X04A 2EFLA 3Q0KA 4PO2A 4EZYA 5TKYA 3B53X 3CVRA 2EX3B 2JNKA 2QFFA 3I01A 2YIAA 4AVMA 4JNEA 3EJRA 4IM3A 2YL8A 2ND1A 1ZWWA 2YKTA 3DDFA 4EZRA 1URUA 3DPPA 4JL9A 4KIKA 5E84A 3CZNA 2Z8YA 2Z0NA 2Z0OA 3HAIA 4HY9A 4AKVA 1DKXA 4DCNC 4EZXA 5C5BA 3LVTA 3EJQA 4EZUA 4D8JA 1O7DB 2ELBA 2FICA 2GF4A 2X3VA 4IM0A 3SOGA 3RV1A 4EZOA 3VKHA 2Q13A 4AZ7A 3C7NA 4EZTA 5FLEX 4F01A 2LXYA 4R5LA 2OBMA 3BVWA 3A98A 3I04A 2PY6A 1SU6A 2F7QA 3D50A 4R5JA 2WYIA 5C5BB 4WPCA 4EZVA 3D4YA 1OAOA 5KBPA 4E81A 4AZHA 3DYTA 1W9MA 2QXLA 3HAHA 1O7DC 1X03A 3SYVA 2GA9D 2WINM 4I1QA 2YIVX 3HAJA 1R5EA 1OA0A 3Q84A 4FZPA 1QX1A 2X3XA 3B51X 3DPQA 2D4CA 3QE6A 3D2FA 3O3OB 3T4AG 4EZZA 3VEAA 3D2EA 3CZSA 3BUBA 3I39X 1QWUA 4AZ5A 1U00A 1E1DA 3CKDA 2RAKA 2WYHA 3EJPA 4G6QA 3L3OM 3CV5A 1DKYA 3D51A 2QKWA 2OZNB 4IWOA 2YL5A 3PLTA 2OW6A 4JLCA 2MI7A 3RPMA 1QWNA 2F1AA 3I2WA 2JNSA 3DX2A 4AZBA 3DX0A 4EZNA 1I49A 1Y2OA 3LLLA 1R34A 3M3WA 4KIKB 4ATMA 2YL6A 2FYVA 4AZCA 4UDYX 2Q12A 4JNFA 4B9QA 1I4LA 4H8SA 4UDXX 1SU8A 4IWQA 1E2UA 2EFKA 3BUIA 3T48A 4AZGA 2F7PA 1GNTA 2OW7A 4F00A 4IWPA 1TQTA 4HR1B 3GI7A 1LQ7A 2YIBA 3BVVA 2X3WA 1I4DA 3D4ZA 3QWEA 4H6IA 4IW0A 3EJUA 4R5GA 2N3KA 3VEBA 2ZXQA 3DPOA 3ABHA 3DX1A 3B52X 4IM2A 2GAFD 2YI8A 4EZWA 1HTYA 3RV0A 4EZQA 2YLAA 1DKZA 3BVUA 4NPHA 1JQKA 3OHXM 1UPXA 3ER9B 3BLBA 3UITA 2V0OA 4FZOA 4E3CA 2YI9A 3EJTA 1HXKA 2YL9A 3ACOA 3EJSA 1I4TA 4JWDA 2RT6A 3KAWA 1MJGA 2X5CA 1GN9A 4BNEA 2Z0VA 4NSWA 4WPEA 4JWEA 1PS3A 1TQUA 3ER8C 2F18A 4NQIA 4AZCB 1TQVA 2KHOA 3O3MB 3BVTA 4H6HA 3DX4A 3F7WA 3QNJA 3QNIA 2RAIA 3OWGA 2OBLA 3T49A 4DYLA 4HYBA 3ERCC 1SUFA 2F1BA 3LMFA 4JWIA 4JWCA 3OK8A 3BUPA 5FIGA 4FM3A 1GNLA 1SU7A 2ALWA 1HWWA 3BVXA 3DDGA 3O3NB 3ZEDA 3T47A 2D1LA 3T46A 1E9VA 4EZSA
chains in the Genus database with same CATH topology
3ABHA 1WDZA 4DCNC 5C5BA 2ELBA 2FICA 3SOGA 2X3VA 2RAKA 3HAIA 2Q13A 3QE6A 3G9GA 2RAJA 3PLTA 2V0OA 3I2WA 3ACOA 1I4TA 5C5BB 4BNEA 1I49A 1Y2OA 3LLLA 2Z0VA 3M3WA 4NSWA 4WPCA 4ATMA 4WPEA 4NQIA 3CAZA 2Q12A 2C08A 1I4LA 4H8SA 4FZSA 1X04A 3QNIA 2RAIA 3DYTA 2EFLA 3HAHA 3Q0KA 2EFKA 4DYLA 1X03A 4AVMA 3SYVA 3OK8A 4I1QA 3Q84A 3HAJA 2YKTA 1ZWWA 2X3WA 1I4DA 3QWEA 1URUA 2D1LA 2X3XA 4AKVA 2D4CA 2Z0NA 2Z0OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ABH A;  1WDZ A;  4DCN C;  5C5B A;  2ELB A;  2FIC A;  3SOG A;  2X3V A;  2RAK A;  3HAI A;  2Q13 A;  3QE6 A;  3G9G A;  2RAJ A;  3PLT A;  2V0O A;  3I2W A;  3ACO A;  1I4T A;  5C5B B;  4BNE A;  1I49 A;  1Y2O A;  3LLL A;  2Z0V A;  3M3W A;  4NSW A;  4WPC A;  4ATM A;  4WPE A;  4NQI A;  3CAZ A;  2Q12 A;  2C08 A;  1I4L A;  4H8S A;  4FZS A;  1X04 A;  3QNI A;  2RAI A;  3DYT A;  2EFL A;  3HAH A;  3Q0K A;  2EFK A;  4DYL A;  1X03 A;  4AVM A;  3SYV A;  3OK8 A;  4I1Q A;  3Q84 A;  3HAJ A;  2YKT A;  1ZWW A;  2X3W A;  1I4D A;  3QWE A;  1URU A;  2D1L A;  2X3X A;  4AKV A;  2D4C A;  2Z0N A;  2Z0O A; 
#chains in the Genus database with same CATH topology
 1OA1 A;  1WDZ A;  1YWM A;  1ZYL A;  1TQW A;  3BUD A;  1R33 A;  3KAV A;  2LM0 A;  3G9G A;  3D52 A;  2OO2 A;  2RAJ A;  4R5I A;  2NCZ A;  2PMR A;  3FD9 A;  2ND0 A;  2F7O A;  1TQS A;  2YLL A;  4AZ6 A;  2F7R A;  4EZP A;  3KDR A;  2EWF A;  2O0I 1;  3BUQ A;  4AZI A;  3L3P A;  4R5K A;  3CAZ A;  4HR1 A;  4JN4 A;  3DX3 A;  3QA8 A;  2C08 A;  4M0M A;  4FZS A;  1X04 A;  2EFL A;  3Q0K A;  4PO2 A;  4EZY A;  5TKY A;  3B53 X;  3CVR A;  2EX3 B;  2JNK A;  2QFF A;  3I01 A;  2YIA A;  4AVM A;  4JNE A;  3EJR A;  4IM3 A;  2YL8 A;  2ND1 A;  1ZWW A;  2YKT A;  3DDF A;  4EZR A;  1URU A;  3DPP A;  4JL9 A;  4KIK A;  5E84 A;  3CZN A;  2Z8Y A;  2Z0N A;  2Z0O A;  3HAI A;  4HY9 A;  4AKV A;  1DKX A;  4DCN C;  4EZX A;  5C5B A;  3LVT A;  3EJQ A;  4EZU A;  4D8J A;  1O7D B;  2ELB A;  2FIC A;  2GF4 A;  2X3V A;  4IM0 A;  3SOG A;  3RV1 A;  4EZO A;  3VKH A;  2Q13 A;  4AZ7 A;  3C7N A;  4EZT A;  5FLE X;  4F01 A;  2LXY A;  4R5L A;  2OBM A;  3BVW A;  3A98 A;  3I04 A;  2PY6 A;  1SU6 A;  2F7Q A;  3D50 A;  4R5J A;  2WYI A;  5C5B B;  4WPC A;  4EZV A;  3D4Y A;  1OAO A;  5KBP A;  4E81 A;  4AZH A;  3DYT A;  1W9M A;  2QXL A;  3HAH A;  1O7D C;  1X03 A;  3SYV A;  2GA9 D;  2WIN M;  4I1Q A;  2YIV X;  3HAJ A;  1R5E A;  1OA0 A;  3Q84 A;  4FZP A;  1QX1 A;  2X3X A;  3B51 X;  3DPQ A;  2D4C A;  3QE6 A;  3D2F A;  3O3O B;  3T4A G;  4EZZ A;  3VEA A;  3D2E A;  3CZS A;  3BUB A;  3I39 X;  1QWU A;  4AZ5 A;  1U00 A;  1E1D A;  3CKD A;  2RAK A;  2WYH A;  3EJP A;  4G6Q A;  3L3O M;  3CV5 A;  1DKY A;  3D51 A;  2QKW A;  2OZN B;  4IWO A;  2YL5 A;  3PLT A;  2OW6 A;  4JLC A;  2MI7 A;  3RPM A;  1QWN A;  2F1A A;  3I2W A;  2JNS A;  3DX2 A;  4AZB A;  3DX0 A;  4EZN A;  1I49 A;  1Y2O A;  3LLL A;  1R34 A;  3M3W A;  4KIK B;  4ATM A;  2YL6 A;  2FYV A;  4AZC A;  4UDY X;  2Q12 A;  4JNF A;  4B9Q A;  1I4L A;  4H8S A;  4UDX X;  1SU8 A;  4IWQ A;  1E2U A;  2EFK A;  3BUI A;  3T48 A;  4AZG A;  2F7P A;  1GNT A;  2OW7 A;  4F00 A;  4IWP A;  1TQT A;  4HR1 B;  3GI7 A;  1LQ7 A;  2YIB A;  3BVV A;  2X3W A;  1I4D A;  3D4Z A;  3QWE A;  4H6I A;  4IW0 A;  3EJU A;  4R5G A;  2N3K A;  3VEB A;  2ZXQ A;  3DPO A;  3ABH A;  3DX1 A;  3B52 X;  4IM2 A;  2GAF D;  2YI8 A;  4EZW A;  1HTY A;  3RV0 A;  4EZQ A;  2YLA A;  1DKZ A;  3BVU A;  4NPH A;  1JQK A;  3OHX M;  1UPX A;  3ER9 B;  3BLB A;  3UIT A;  2V0O A;  4FZO A;  4E3C A;  2YI9 A;  3EJT A;  1HXK A;  2YL9 A;  3ACO A;  3EJS A;  1I4T A;  4JWD A;  2RT6 A;  3KAW A;  1MJG A;  2X5C A;  1GN9 A;  4BNE A;  2Z0V A;  4NSW A;  4WPE A;  4JWE A;  1PS3 A;  1TQU A;  3ER8 C;  2F18 A;  4NQI A;  4AZC B;  1TQV A;  2KHO A;  3O3M B;  3BVT A;  4H6H A;  3DX4 A;  3F7W A;  3QNJ A;  3QNI A;  2RAI A;  3OWG A;  2OBL A;  3T49 A;  4DYL A;  4HYB A;  3ERC C;  1SUF A;  2F1B A;  3LMF A;  4JWI A;  4JWC A;  3OK8 A;  3BUP A;  5FIG A;  4FM3 A;  1GNL A;  1SU7 A;  2ALW A;  1HWW A;  3BVX A;  3DDG A;  3O3N B;  3ZED A;  3T47 A;  2D1L A;  3T46 A;  1E9V A;  4EZS A; 
#chains in the Genus database with same CATH homology
 3ABH A;  1WDZ A;  4DCN C;  5C5B A;  2ELB A;  2FIC A;  3SOG A;  2X3V A;  2RAK A;  3HAI A;  2Q13 A;  3QE6 A;  3G9G A;  2RAJ A;  3PLT A;  2V0O A;  3I2W A;  3ACO A;  1I4T A;  5C5B B;  4BNE A;  1I49 A;  1Y2O A;  3LLL A;  2Z0V A;  3M3W A;  4NSW A;  4WPC A;  4ATM A;  4WPE A;  4NQI A;  3CAZ A;  2Q12 A;  2C08 A;  1I4L A;  4H8S A;  4FZS A;  1X04 A;  3QNI A;  2RAI A;  3DYT A;  2EFL A;  3HAH A;  3Q0K A;  2EFK A;  4DYL A;  1X03 A;  4AVM A;  3SYV A;  3OK8 A;  4I1Q A;  3Q84 A;  3HAJ A;  2YKT A;  1ZWW A;  2X3W A;  1I4D A;  3QWE A;  1URU A;  2D1L A;  2X3X A;  4AKV A;  2D4C A;  2Z0N A;  2Z0O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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