3Q0KA

Crystal structure of human pacsin 2 f-bar
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
289
structure length
287
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKAPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQEEW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Protein kinase C and casein kinase substrate in neurons prot
publication title Crystal structure of human PACSIN 2 F-BAR domain
rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 113
structure length 287
sequence length 289
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2010-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3q0kA01
2EFKA 3LLLA 1X04A 2Q12A 2X3VA 2X3XA 4WPCA 3PLTA 3ABHA 4AVMA 2V0OA 2EFLA 4NSWA 4FZSA 2D1LA 3Q0KA 2RAKA 2YKTA 5C5BB 1I4LA 2Q13A 1I4DA 3M3WA 2D4CA 3QE6A 1WDZA 4BNEA 4DYLA 2Z0OA 3QNIA 3ACOA 3QWEA 4I1QA 5C5BA 4DCNC 3HAIA 1I49A 3OK8A 3HAHA 1X03A 2RAJA 2ELBA 2RAIA 4WPEA 3Q84A 4NQIA 1ZWWA 3I2WA 2Z0VA 1Y2OA 3G9GA 3SOGA 3DYTA 3HAJA 3SYVA 4ATMA 2X3WA 2C08A 2Z0NA 3CAZA 4H8SA 1URUA 2FICA 4AKVA 1I4TA
chains in the Genus database with same CATH superfamily
3RV0A 4H6IA 3DX1A 5C5BB 3LMFA 3RV1A 4JWIA 4EZOA 2Z0OA 1DKXA 5FIGA 4AZIA 3KAWA 1ZYLA 4NQIA 3BUDA 3I01A 3B51X 4R5IA 4ATMA 3DDFA 2X3WA 4JWDA 4EZPA 4EZTA 2YL6A 4EZNA 5TKYA 2ZXQA 1SU6A 2JNKA 2LM0A 4BNEA 1DKYA 2WINM 2YIVX 1ZWWA 1OA0A 4IWQA 1R33A 4R5KA 3DDGA 1HTYA 3LVTA 4IM3A 4G6QA 2NCZA 4AVMA 3EJPA 3PLTA 2ALWA 4JNFA 2D4CA 1E1DA 4R5GA 1E2UA 3FD9A 3I2WA 1TQVA 4KIKB 5KBPA 3T49A 3VEBA 4JNEA 4JL9A 1DKZA 1E9VA 2EFLA 2F7QA 2JNSA 2F1AA 2YKTA 3ER9B 3VEAA 2Q13A 1I4DA 2N3KA 3CV5A 2RAJA 2Z0VA 1Y2OA 3B53X 3BUPA 3ZEDA 4IM2A 3HAJA 4AZGA 2Q12A 2X3VA 3L3PA 4FZSA 1O7DB 1TQSA 4FZPA 2YL5A 3HAIA 4EZWA 4JWEA 3C7NA 4D8JA 3SOGA 3SYVA 1QWNA 1URUA 1GN9A 4EZVA 3BVWA 3RPMA 3ABHA 4HR1B 2PMRA 3Q0KA 1O7DC 3T48A 3B52X 3BVXA 2RT6A 3M3WA 2F7RA 3QE6A 4FZOA 2OO2A 3DPPA 2WYHA 4F00A 3T4AG 4DCNC 1I49A 3QNJA 2ELBA 4E81A 2QFFA 4M0MA 2O0I1 4DYLA 3O3MB 2YI9A 2OBLA 4WPCA 2PY6A 3DX0A 4JLCA 3VKHA 4AZCB 4EZXA 2MI7A 1OA1A 3BUQA 2EWFA 3OHXM 4UDXX 5FLEX 2ND1A 1GNTA 3EJRA 1R34A 2YLAA 4AZBA 3DX2A 4HYBA 1UPXA 3DX4A 2KHOA 2ND0A 1U00A 2GAFD 4PO2A 2YIAA 3D4ZA 2OW6A 4E3CA 2OBMA 3CAZA 3EJSA 4AZHA 4EZUA 4IW0A 2V0OA 4NSWA 3BVUA 2GA9D 3O3OB 1QX1A 4JWCA 3KAVA 1YWMA 1MJGA 3BLBA 4EZSA 4R5JA 5E84A 3CZNA 2FYVA 2QKWA 2X5CA 2OZNB 3BUBA 5C5BA 1X03A 3D50A 3DPQA 3CZSA 4AKVA 2C08A 2F7PA 4H8SA 1TQUA 4R5LA 4JN4A 2WYIA 3BUIA 3BVVA 3D52A 4H6HA 3ERCC 3EJUA 3GI7A 4IWOA 2LXYA 3BVTA 3ER8C 2RAIA 3Q84A 3I39X 4AZ5A 4IM0A 4FM3A 2D1LA 1SUFA 3DX3A 3QNIA 4I1QA 3CVRA 2YLLA 2F1BA 2OW7A 3OWGA 4EZRA 3D4YA 4HY9A 1R5EA 4KIKA 1I4TA 2EFKA 3EJTA 4F01A 1QWUA 2F18A 4AZ6A 1SU7A 1JQKA 3ACOA 3KDRA 3QWEA 1GNLA 3EJQA 2YIBA 3LLLA 3D2EA 4NPHA 3D2FA 1TQWA 3UITA 1SU8A 3DPOA 2Z8YA 3L3OM 3I04A 4WPEA 2YI8A 2YL8A 3G9GA 4IWPA 1W9MA 2RAKA 4HR1A 1PS3A 4EZYA 3OK8A 3HAHA 3A98A 3T47A 3D51A 1LQ7A 2GF4A 2YL9A 3O3NB 3DYTA 4EZQA 2Z0NA 2FICA 1X04A 2X3XA 4UDYX 4B9QA 1TQTA 1HWWA 1I4LA 1OAOA 1WDZA 3QA8A 3T46A 4AZCA 3F7WA 1HXKA 2F7OA 2QXLA 3CKDA 4AZ7A 2EX3B 4EZZA
chains in the Genus database with same CATH topology
2EFKA 3LLLA 1X04A 2Q12A 2X3VA 2X3XA 4WPCA 3PLTA 3ABHA 4AVMA 2V0OA 2EFLA 4NSWA 4FZSA 2D1LA 3Q0KA 2RAKA 2YKTA 5C5BB 1I4LA 2Q13A 1I4DA 3M3WA 2D4CA 3QE6A 1WDZA 4BNEA 4DYLA 2Z0OA 3QNIA 3ACOA 3QWEA 4I1QA 5C5BA 4DCNC 3HAIA 1I49A 3OK8A 3HAHA 1X03A 2RAJA 2ELBA 2RAIA 4WPEA 3Q84A 4NQIA 1ZWWA 3I2WA 2Z0VA 1Y2OA 3G9GA 3SOGA 3DYTA 3HAJA 3SYVA 4ATMA 2X3WA 2C08A 2Z0NA 3CAZA 4H8SA 1URUA 2FICA 4AKVA 1I4TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EFK A;  3LLL A;  1X04 A;  2Q12 A;  2X3V A;  2X3X A;  4WPC A;  3PLT A;  3ABH A;  4AVM A;  2V0O A;  2EFL A;  4NSW A;  4FZS A;  2D1L A;  3Q0K A;  2RAK A;  2YKT A;  5C5B B;  1I4L A;  2Q13 A;  1I4D A;  3M3W A;  2D4C A;  3QE6 A;  1WDZ A;  4BNE A;  4DYL A;  2Z0O A;  3QNI A;  3ACO A;  3QWE A;  4I1Q A;  5C5B A;  4DCN C;  3HAI A;  1I49 A;  3OK8 A;  3HAH A;  1X03 A;  2RAJ A;  2ELB A;  2RAI A;  4WPE A;  3Q84 A;  4NQI A;  1ZWW A;  3I2W A;  2Z0V A;  1Y2O A;  3G9G A;  3SOG A;  3DYT A;  3HAJ A;  3SYV A;  4ATM A;  2X3W A;  2C08 A;  2Z0N A;  3CAZ A;  4H8S A;  1URU A;  2FIC A;  4AKV A;  1I4T A; 
#chains in the Genus database with same CATH topology
 3RV0 A;  4H6I A;  3DX1 A;  5C5B B;  3LMF A;  3RV1 A;  4JWI A;  4EZO A;  2Z0O A;  1DKX A;  5FIG A;  4AZI A;  3KAW A;  1ZYL A;  4NQI A;  3BUD A;  3I01 A;  3B51 X;  4R5I A;  4ATM A;  3DDF A;  2X3W A;  4JWD A;  4EZP A;  4EZT A;  2YL6 A;  4EZN A;  5TKY A;  2ZXQ A;  1SU6 A;  2JNK A;  2LM0 A;  4BNE A;  1DKY A;  2WIN M;  2YIV X;  1ZWW A;  1OA0 A;  4IWQ A;  1R33 A;  4R5K A;  3DDG A;  1HTY A;  3LVT A;  4IM3 A;  4G6Q A;  2NCZ A;  4AVM A;  3EJP A;  3PLT A;  2ALW A;  4JNF A;  2D4C A;  1E1D A;  4R5G A;  1E2U A;  3FD9 A;  3I2W A;  1TQV A;  4KIK B;  5KBP A;  3T49 A;  3VEB A;  4JNE A;  4JL9 A;  1DKZ A;  1E9V A;  2EFL A;  2F7Q A;  2JNS A;  2F1A A;  2YKT A;  3ER9 B;  3VEA A;  2Q13 A;  1I4D A;  2N3K A;  3CV5 A;  2RAJ A;  2Z0V A;  1Y2O A;  3B53 X;  3BUP A;  3ZED A;  4IM2 A;  3HAJ A;  4AZG A;  2Q12 A;  2X3V A;  3L3P A;  4FZS A;  1O7D B;  1TQS A;  4FZP A;  2YL5 A;  3HAI A;  4EZW A;  4JWE A;  3C7N A;  4D8J A;  3SOG A;  3SYV A;  1QWN A;  1URU A;  1GN9 A;  4EZV A;  3BVW A;  3RPM A;  3ABH A;  4HR1 B;  2PMR A;  3Q0K A;  1O7D C;  3T48 A;  3B52 X;  3BVX A;  2RT6 A;  3M3W A;  2F7R A;  3QE6 A;  4FZO A;  2OO2 A;  3DPP A;  2WYH A;  4F00 A;  3T4A G;  4DCN C;  1I49 A;  3QNJ A;  2ELB A;  4E81 A;  2QFF A;  4M0M A;  2O0I 1;  4DYL A;  3O3M B;  2YI9 A;  2OBL A;  4WPC A;  2PY6 A;  3DX0 A;  4JLC A;  3VKH A;  4AZC B;  4EZX A;  2MI7 A;  1OA1 A;  3BUQ A;  2EWF A;  3OHX M;  4UDX X;  5FLE X;  2ND1 A;  1GNT A;  3EJR A;  1R34 A;  2YLA A;  4AZB A;  3DX2 A;  4HYB A;  1UPX A;  3DX4 A;  2KHO A;  2ND0 A;  1U00 A;  2GAF D;  4PO2 A;  2YIA A;  3D4Z A;  2OW6 A;  4E3C A;  2OBM A;  3CAZ A;  3EJS A;  4AZH A;  4EZU A;  4IW0 A;  2V0O A;  4NSW A;  3BVU A;  2GA9 D;  3O3O B;  1QX1 A;  4JWC A;  3KAV A;  1YWM A;  1MJG A;  3BLB A;  4EZS A;  4R5J A;  5E84 A;  3CZN A;  2FYV A;  2QKW A;  2X5C A;  2OZN B;  3BUB A;  5C5B A;  1X03 A;  3D50 A;  3DPQ A;  3CZS A;  4AKV A;  2C08 A;  2F7P A;  4H8S A;  1TQU A;  4R5L A;  4JN4 A;  2WYI A;  3BUI A;  3BVV A;  3D52 A;  4H6H A;  3ERC C;  3EJU A;  3GI7 A;  4IWO A;  2LXY A;  3BVT A;  3ER8 C;  2RAI A;  3Q84 A;  3I39 X;  4AZ5 A;  4IM0 A;  4FM3 A;  2D1L A;  1SUF A;  3DX3 A;  3QNI A;  4I1Q A;  3CVR A;  2YLL A;  2F1B A;  2OW7 A;  3OWG A;  4EZR A;  3D4Y A;  4HY9 A;  1R5E A;  4KIK A;  1I4T A;  2EFK A;  3EJT A;  4F01 A;  1QWU A;  2F18 A;  4AZ6 A;  1SU7 A;  1JQK A;  3ACO A;  3KDR A;  3QWE A;  1GNL A;  3EJQ A;  2YIB A;  3LLL A;  3D2E A;  4NPH A;  3D2F A;  1TQW A;  3UIT A;  1SU8 A;  3DPO A;  2Z8Y A;  3L3O M;  3I04 A;  4WPE A;  2YI8 A;  2YL8 A;  3G9G A;  4IWP A;  1W9M A;  2RAK A;  4HR1 A;  1PS3 A;  4EZY A;  3OK8 A;  3HAH A;  3A98 A;  3T47 A;  3D51 A;  1LQ7 A;  2GF4 A;  2YL9 A;  3O3N B;  3DYT A;  4EZQ A;  2Z0N A;  2FIC A;  1X04 A;  2X3X A;  4UDY X;  4B9Q A;  1TQT A;  1HWW A;  1I4L A;  1OAO A;  1WDZ A;  3QA8 A;  3T46 A;  4AZC A;  3F7W A;  1HXK A;  2F7O A;  2QXL A;  3CKD A;  4AZ7 A;  2EX3 B;  4EZZ A; 
#chains in the Genus database with same CATH homology
 2EFK A;  3LLL A;  1X04 A;  2Q12 A;  2X3V A;  2X3X A;  4WPC A;  3PLT A;  3ABH A;  4AVM A;  2V0O A;  2EFL A;  4NSW A;  4FZS A;  2D1L A;  3Q0K A;  2RAK A;  2YKT A;  5C5B B;  1I4L A;  2Q13 A;  1I4D A;  3M3W A;  2D4C A;  3QE6 A;  1WDZ A;  4BNE A;  4DYL A;  2Z0O A;  3QNI A;  3ACO A;  3QWE A;  4I1Q A;  5C5B A;  4DCN C;  3HAI A;  1I49 A;  3OK8 A;  3HAH A;  1X03 A;  2RAJ A;  2ELB A;  2RAI A;  4WPE A;  3Q84 A;  4NQI A;  1ZWW A;  3I2W A;  2Z0V A;  1Y2O A;  3G9G A;  3SOG A;  3DYT A;  3HAJ A;  3SYV A;  4ATM A;  2X3W A;  2C08 A;  2Z0N A;  3CAZ A;  4H8S A;  1URU A;  2FIC A;  4AKV A;  1I4T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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