The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
306
|
sequence length |
911
|
structure length |
905
|
Chain Sequence |
GLEVLFQGPAMATKKVHIISHSHWDREWYMAYEQHHMRLINLIDDLLEVFQTDPDFHSFHLDGQTIILDDYLKVRPEREPEIRQAIASGKLRIGPFYILQDDFLTSSESNVRNMLIGKEDCDRWGASVPLGYFPDTFGNMGQTPQLMLKAGLQAAAFGRGIRPTGFNNQVDTSEKYSSQFSEISWQGPDNSRILGLLFANWYSNGNEIPTTEAEARLFWDKKLADAERFASTKHLLMMNGCDHQPVQLDVTKAIALANQLYPDYEFVHSCFEDYLADLADDLPENLSTVQGEITSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLAAMAYEVTSTYPHDQLRYAWKTLMQNHPHDSICGCSVDSVHREMMTRFEKAYEVGHYLAKEAAKQIADAIDTRDFPMDSQPFVLFNTSGHSKTSVAELSLTWKKYHFGQRFPKEVYQEAQEYLARLSQSFQIIDTSGQVRPEAEILGTSIAFDYDLPKRSFREPYFAIKVRLRLPITLPAMSWKTLALKLGNTVSLYDDSNQCLENGFLKVMIQTDGRLTITDKQSGLIYQDLLRFEDCGDIGNEYISRQPNHDQPFYADQGTIKLNIISNTAQVAELEIQQTFAIPISADKLLQAEMEAVIDITERQARRSQEKAELTLTTLIRMEKNNPRLQFTTRFDNQMTNHRLRVLFPTHLKTDHHLADSIFETVKRPNHPDATFWKNPSNPQHQECFVSLFDGENGVTIGNYGLNEYEILPDTNTIAITLLRSVGEMGDWGYFPTPEAQCLGKHSLSYSFESITKQTQFASYWRAQEGQVPVITTQTNQHEGTLAAEYSYLTGTNDQVALTAFKRRLADNALITRSYNLSNDKTCDFSLSLPNYNAKVTNLLEKDSKQSTPSQLGKAEILTLAWKKQ
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure and Kinetic Investigation of Streptococcus Pyogenes Family Gh38 Alpha-Mannosidase
pubmed doi rcsb |
| source organism |
Streptococcus pyogenes
|
| molecule tags |
Hydrolase
|
| molecule keywords |
ALPHA-MANNOSIDASE
|
| total genus |
306
|
| structure length |
905
|
| sequence length |
911
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
3.2.1.24: Alpha-mannosidase. |
| pdb deposition date | 2009-11-16 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01074 | Glyco_hydro_38N | Glycosyl hydrolases family 38 N-terminal domain |
| A | PF07748 | Glyco_hydro_38C | Glycosyl hydrolases family 38 C-terminal domain |
| A | PF09261 | Alpha-mann_mid | Alpha mannosidase middle domain |
| A | PF17677 | Glyco_hydro38C2 | Glycosyl hydrolases family 38 C-terminal beta sandwich domain |
| A | PF18438 | Glyco_hydro_38 | Glycosyl hydrolases family 38 C-terminal domain 1 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Substrate Binding Domain Of Dnak; Chain:A; Domain 2 | Glycoside hydrolase family 38, central domain | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulin-like | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulin-like | ||
| Mainly Beta | Distorted Sandwich | Beta-galactosidase; Chain A, domain 5 | Golgi alpha-mannosidase II; domain 4 | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Rossmann fold | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Rossmann fold |
