3HAJA

Crystal structure of human pacsin2 f-bar domain (p212121 lattice)
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
286
structure length
286
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords human PACSIN2 F-BAR
publication title Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 107
structure length 286
sequence length 286
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3hajA01
1I4LA 3Q84A 4BNEA 3LLLA 1URUA 1I4TA 2EFLA 3HAHA 5C5BB 4AVMA 4DYLA 3HAIA 4I1QA 2C08A 4AKVA 3M3WA 3DYTA 3SYVA 3G9GA 3OK8A 2ELBA 2X3WA 3SOGA 1Y2OA 2Z0NA 1WDZA 2X3VA 2YKTA 2RAKA 1I4DA 2Z0OA 3PLTA 1I49A 2X3XA 4FZSA 4WPCA 4NQIA 2V0OA 4NSWA 1X03A 2D1LA 3CAZA 2Q12A 3ABHA 3QWEA 5C5BA 1X04A 2RAIA 2Z0VA 4H8SA 2D4CA 2EFKA 2RAJA 4WPEA 2FICA 3ACOA 3QE6A 3HAJA 3QNIA 4DCNC 1ZWWA 3Q0KA 2Q13A 4ATMA 3I2WA
chains in the Genus database with same CATH superfamily
3LLLA 1OAOA 3DX3A 3VEAA 4R5JA 4EZYA 2ND0A 2Q12A 2YLLA 1X04A 2Z0VA 4IWPA 2WINM 3ACOA 1YWMA 4AZ5A 2GAFD 4HR1A 5TKYA 1E1DA 2ELBA 3DX0A 3BUDA 3VKHA 4R5LA 2NCZA 3OHXM 3D52A 3L3OM 4R5KA 3Q84A 3EJPA 4JWEA 1WDZA 4IWOA 4JWCA 4WPCA 4AZCA 4NSWA 3LMFA 3QWEA 3RV0A 4JWIA 4AZIA 4AZGA 2YL6A 1DKXA 4AZ7A 3DPQA 3KAWA 3I39X 3DDGA 1OA1A 2WYIA 2EFLA 3BUPA 4AKVA 2F1AA 2OW7A 2ZXQA 4PO2A 3CVRA 5KBPA 4FZSA 4IM3A 2OZNB 4EZOA 3C7NA 2OO2A 3DPOA 3KDRA 4ATMA 1I4LA 5C5BB 3DDFA 4AZ6A 4FZOA 1HTYA 2PY6A 2ALWA 1U00A 3PLTA 1OA0A 5FLEX 3RV1A 1SU7A 5E84A 5FIGA 2MI7A 4H8SA 4WPEA 3KAVA 2FICA 3HAJA 4F00A 3ER9B 4EZTA 1GNLA 3HAHA 4E81A 4AVMA 2Z8YA 3T47A 1SUFA 2YL8A 1R34A 2X3VA 2YKTA 1I49A 4EZVA 1E2UA 3EJQA 3ZEDA 2EFKA 1SU8A 2WYHA 3EJSA 1R33A 4M0MA 4EZPA 3T48A 2F7RA 4JWDA 1TQSA 4IM0A 2OW6A 2OBLA 2YL5A 3I01A 2Z0OA 1PS3A 4EZRA 1W9MA 4EZSA 3CAZA 3ABHA 1LQ7A 3EJTA 4JL9A 3VEBA 4JN4A 2N3KA 2PMRA 4IW0A 2YIBA 3QA8A 3BVWA 1Y2OA 3B53X 1JQKA 3LVTA 3T46A 2RAKA 2GA9D 3O3MB 3BUIA 2EX3B 3BLBA 3FD9A 3QE6A 3I04A 2JNKA 2FYVA 4UDYX 3HAIA 2YI8A 1TQUA 2F7OA 3SOGA 2Z0NA 2YL9A 4EZWA 4EZXA 4HR1B 4AZHA 1SU6A 2RT6A 4JNEA 3D2EA 2RAIA 1E9VA 3CZSA 3F7WA 4H6HA 4EZNA 3T4AG 3BVTA 4DYLA 4FZPA 3M3WA 1TQVA 1UPXA 2YIVX 3EJUA 3T49A 3BVVA 3CV5A 2EWFA 4FM3A 1O7DB 4EZQA 3QNJA 2D4CA 1O7DC 4E3CA 1GNTA 4IM2A 3DX4A 1MJGA 4I1QA 3DYTA 1R5EA 3G9GA 3DX2A 1I4DA 3BVXA 4B9QA 4NQIA 4AZBA 3D51A 2GF4A 3ER8C 1GN9A 3Q0KA 1DKZA 2Q13A 2F1BA 4HY9A 4NPHA 3BVUA 2LXYA 2QFFA 2X3WA 3L3PA 4KIKB 2V0OA 1ZYLA 2QKWA 1HXKA 1URUA 4H6IA 3D4YA 4EZZA 2OBMA 1QX1A 2X5CA 4IWQA 2QXLA 3D2FA 3OWGA 1X03A 3BUBA 5C5BA 3B51X 1QWUA 3A98A 2RAJA 4JLCA 4G6QA 1ZWWA 3CKDA 4R5GA 2C08A 3O3NB 3GI7A 3SYVA 3OK8A 1QWNA 3BUQA 4EZUA 1TQTA 2D1LA 2JNSA 2LM0A 2KHOA 2O0I1 2F7PA 2YI9A 1TQWA 3D4ZA 3CZNA 3I2WA 4D8JA 4BNEA 3RPMA 2F18A 2X3XA 2ND1A 3UITA 1DKYA 1HWWA 3D50A 3EJRA 4UDXX 3O3OB 4KIKA 4AZCB 1I4TA 4F01A 3B52X 3DX1A 3DPPA 4HYBA 4JNFA 2F7QA 3ERCC 4R5IA 2YLAA 2YIAA 3QNIA 4DCNC
chains in the Genus database with same CATH topology
1I4LA 3Q84A 4BNEA 3LLLA 1URUA 1I4TA 2EFLA 3HAHA 5C5BB 4AVMA 4DYLA 3HAIA 4I1QA 2C08A 4AKVA 3M3WA 3DYTA 3SYVA 3G9GA 3OK8A 2ELBA 2X3WA 3SOGA 1Y2OA 2Z0NA 1WDZA 2X3VA 2YKTA 2RAKA 1I4DA 2Z0OA 3PLTA 1I49A 2X3XA 4FZSA 4WPCA 4NQIA 2V0OA 4NSWA 1X03A 2D1LA 3CAZA 2Q12A 3ABHA 3QWEA 5C5BA 1X04A 2RAIA 2Z0VA 4H8SA 2D4CA 2EFKA 2RAJA 4WPEA 2FICA 3ACOA 3QE6A 3HAJA 3QNIA 4DCNC 1ZWWA 3Q0KA 2Q13A 4ATMA 3I2WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I4L A;  3Q84 A;  4BNE A;  3LLL A;  1URU A;  1I4T A;  2EFL A;  3HAH A;  5C5B B;  4AVM A;  4DYL A;  3HAI A;  4I1Q A;  2C08 A;  4AKV A;  3M3W A;  3DYT A;  3SYV A;  3G9G A;  3OK8 A;  2ELB A;  2X3W A;  3SOG A;  1Y2O A;  2Z0N A;  1WDZ A;  2X3V A;  2YKT A;  2RAK A;  1I4D A;  2Z0O A;  3PLT A;  1I49 A;  2X3X A;  4FZS A;  4WPC A;  4NQI A;  2V0O A;  4NSW A;  1X03 A;  2D1L A;  3CAZ A;  2Q12 A;  3ABH A;  3QWE A;  5C5B A;  1X04 A;  2RAI A;  2Z0V A;  4H8S A;  2D4C A;  2EFK A;  2RAJ A;  4WPE A;  2FIC A;  3ACO A;  3QE6 A;  3HAJ A;  3QNI A;  4DCN C;  1ZWW A;  3Q0K A;  2Q13 A;  4ATM A;  3I2W A; 
#chains in the Genus database with same CATH topology
 3LLL A;  1OAO A;  3DX3 A;  3VEA A;  4R5J A;  4EZY A;  2ND0 A;  2Q12 A;  2YLL A;  1X04 A;  2Z0V A;  4IWP A;  2WIN M;  3ACO A;  1YWM A;  4AZ5 A;  2GAF D;  4HR1 A;  5TKY A;  1E1D A;  2ELB A;  3DX0 A;  3BUD A;  3VKH A;  4R5L A;  2NCZ A;  3OHX M;  3D52 A;  3L3O M;  4R5K A;  3Q84 A;  3EJP A;  4JWE A;  1WDZ A;  4IWO A;  4JWC A;  4WPC A;  4AZC A;  4NSW A;  3LMF A;  3QWE A;  3RV0 A;  4JWI A;  4AZI A;  4AZG A;  2YL6 A;  1DKX A;  4AZ7 A;  3DPQ A;  3KAW A;  3I39 X;  3DDG A;  1OA1 A;  2WYI A;  2EFL A;  3BUP A;  4AKV A;  2F1A A;  2OW7 A;  2ZXQ A;  4PO2 A;  3CVR A;  5KBP A;  4FZS A;  4IM3 A;  2OZN B;  4EZO A;  3C7N A;  2OO2 A;  3DPO A;  3KDR A;  4ATM A;  1I4L A;  5C5B B;  3DDF A;  4AZ6 A;  4FZO A;  1HTY A;  2PY6 A;  2ALW A;  1U00 A;  3PLT A;  1OA0 A;  5FLE X;  3RV1 A;  1SU7 A;  5E84 A;  5FIG A;  2MI7 A;  4H8S A;  4WPE A;  3KAV A;  2FIC A;  3HAJ A;  4F00 A;  3ER9 B;  4EZT A;  1GNL A;  3HAH A;  4E81 A;  4AVM A;  2Z8Y A;  3T47 A;  1SUF A;  2YL8 A;  1R34 A;  2X3V A;  2YKT A;  1I49 A;  4EZV A;  1E2U A;  3EJQ A;  3ZED A;  2EFK A;  1SU8 A;  2WYH A;  3EJS A;  1R33 A;  4M0M A;  4EZP A;  3T48 A;  2F7R A;  4JWD A;  1TQS A;  4IM0 A;  2OW6 A;  2OBL A;  2YL5 A;  3I01 A;  2Z0O A;  1PS3 A;  4EZR A;  1W9M A;  4EZS A;  3CAZ A;  3ABH A;  1LQ7 A;  3EJT A;  4JL9 A;  3VEB A;  4JN4 A;  2N3K A;  2PMR A;  4IW0 A;  2YIB A;  3QA8 A;  3BVW A;  1Y2O A;  3B53 X;  1JQK A;  3LVT A;  3T46 A;  2RAK A;  2GA9 D;  3O3M B;  3BUI A;  2EX3 B;  3BLB A;  3FD9 A;  3QE6 A;  3I04 A;  2JNK A;  2FYV A;  4UDY X;  3HAI A;  2YI8 A;  1TQU A;  2F7O A;  3SOG A;  2Z0N A;  2YL9 A;  4EZW A;  4EZX A;  4HR1 B;  4AZH A;  1SU6 A;  2RT6 A;  4JNE A;  3D2E A;  2RAI A;  1E9V A;  3CZS A;  3F7W A;  4H6H A;  4EZN A;  3T4A G;  3BVT A;  4DYL A;  4FZP A;  3M3W A;  1TQV A;  1UPX A;  2YIV X;  3EJU A;  3T49 A;  3BVV A;  3CV5 A;  2EWF A;  4FM3 A;  1O7D B;  4EZQ A;  3QNJ A;  2D4C A;  1O7D C;  4E3C A;  1GNT A;  4IM2 A;  3DX4 A;  1MJG A;  4I1Q A;  3DYT A;  1R5E A;  3G9G A;  3DX2 A;  1I4D A;  3BVX A;  4B9Q A;  4NQI A;  4AZB A;  3D51 A;  2GF4 A;  3ER8 C;  1GN9 A;  3Q0K A;  1DKZ A;  2Q13 A;  2F1B A;  4HY9 A;  4NPH A;  3BVU A;  2LXY A;  2QFF A;  2X3W A;  3L3P A;  4KIK B;  2V0O A;  1ZYL A;  2QKW A;  1HXK A;  1URU A;  4H6I A;  3D4Y A;  4EZZ A;  2OBM A;  1QX1 A;  2X5C A;  4IWQ A;  2QXL A;  3D2F A;  3OWG A;  1X03 A;  3BUB A;  5C5B A;  3B51 X;  1QWU A;  3A98 A;  2RAJ A;  4JLC A;  4G6Q A;  1ZWW A;  3CKD A;  4R5G A;  2C08 A;  3O3N B;  3GI7 A;  3SYV A;  3OK8 A;  1QWN A;  3BUQ A;  4EZU A;  1TQT A;  2D1L A;  2JNS A;  2LM0 A;  2KHO A;  2O0I 1;  2F7P A;  2YI9 A;  1TQW A;  3D4Z A;  3CZN A;  3I2W A;  4D8J A;  4BNE A;  3RPM A;  2F18 A;  2X3X A;  2ND1 A;  3UIT A;  1DKY A;  1HWW A;  3D50 A;  3EJR A;  4UDX X;  3O3O B;  4KIK A;  4AZC B;  1I4T A;  4F01 A;  3B52 X;  3DX1 A;  3DPP A;  4HYB A;  4JNF A;  2F7Q A;  3ERC C;  4R5I A;  2YLA A;  2YIA A;  3QNI A;  4DCN C; 
#chains in the Genus database with same CATH homology
 1I4L A;  3Q84 A;  4BNE A;  3LLL A;  1URU A;  1I4T A;  2EFL A;  3HAH A;  5C5B B;  4AVM A;  4DYL A;  3HAI A;  4I1Q A;  2C08 A;  4AKV A;  3M3W A;  3DYT A;  3SYV A;  3G9G A;  3OK8 A;  2ELB A;  2X3W A;  3SOG A;  1Y2O A;  2Z0N A;  1WDZ A;  2X3V A;  2YKT A;  2RAK A;  1I4D A;  2Z0O A;  3PLT A;  1I49 A;  2X3X A;  4FZS A;  4WPC A;  4NQI A;  2V0O A;  4NSW A;  1X03 A;  2D1L A;  3CAZ A;  2Q12 A;  3ABH A;  3QWE A;  5C5B A;  1X04 A;  2RAI A;  2Z0V A;  4H8S A;  2D4C A;  2EFK A;  2RAJ A;  4WPE A;  2FIC A;  3ACO A;  3QE6 A;  3HAJ A;  3QNI A;  4DCN C;  1ZWW A;  3Q0K A;  2Q13 A;  4ATM A;  3I2W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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