3HAJA

Crystal structure of human pacsin2 f-bar domain (p212121 lattice)
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
286
structure length
286
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Endocytosis
molecule keywords human PACSIN2 F-BAR
publication title Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.
pubmed doi rcsb
source organism Homo sapiens
total genus 107
structure length 286
sequence length 286
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3hajA01
3OK8A 4NQIA 4AKVA 2Z0NA 2V0OA 3QWEA 4ATMA 1I49A 3PLTA 4AVMA 2Z0OA 4DCNC 3M3WA 1I4TA 1I4DA 3HAHA 2EFKA 3ABHA 3HAIA 2Q12A 3LLLA 3Q0KA 4DYLA 4WPEA 1X04A 2D4CA 2Z0VA 4H8SA 3Q84A 2EFLA 2YKTA 4WPCA 2FICA 2X3WA 2X3VA 5C5BA 2RAKA 3QE6A 4NSWA 4FZSA 3HAJA 4BNEA 2RAIA 1URUA 1WDZA 3SOGA 3I2WA 3CAZA 3G9GA 1X03A 3DYTA 4I1QA 1Y2OA 2RAJA 3QNIA 2ELBA 3SYVA 5C5BB 2D1LA 2C08A 2X3XA 3ACOA 1I4LA 2Q13A 1ZWWA
chains in the Genus database with same CATH superfamily
3OK8A 2V0OA 4EZQA 3QNJA 3HAHA 3ABHA 3ERCC 4F00A 3DX4A 1DKYA 2X5CA 4FM3A 2F7QA 4PO2A 4B9QA 5FLEX 3A98A 3BVVA 4H6IA 2GF4A 2F7PA 3QNIA 4AZ5A 2D1LA 2OZNB 3L3PA 4EZRA 1QX1A 4M0MA 1TQTA 2EFKA 3DX0A 3HAIA 4NPHA 4DYLA 1LQ7A 1W9MA 4E3CA 1QWUA 4JWIA 3BVTA 4EZTA 3SOGA 3DYTA 1ZYLA 4UDXX 1PS3A 2YIAA 2F7OA 4F01A 4D8JA 3LLLA 3KDRA 2EFLA 1JQKA 3VKHA 4FZSA 2RAIA 1WDZA 4E81A 3BUIA 1TQSA 2PY6A 1U00A 3RPMA 4EZWA 1UPXA 2YL5A 3KAWA 1E2UA 4H6HA 1YWMA 3BUDA 2RT6A 2ZXQA 1OA1A 3CVRA 4JL9A 3T47A 2YIVX 4HR1B 4G6QA 5E84A 4EZNA 2ND0A 4HYBA 1HTYA 3ZEDA 3HAJA 2F7RA 1SU7A 3I39X 3O3NB 3CKDA 3LMFA 4UDYX 3EJQA 2NCZA 3EJPA 4IWPA 3QE6A 2YLAA 4R5LA 3L3OM 1URUA 3DX2A 3KAVA 4I1QA 1SUFA 2X3XA 2QXLA 3D2FA 4NQIA 2Z0NA 1OAOA 2F18A 3EJUA 4JWEA 4HR1A 1R5EA 4WPEA 2RAKA 4JWCA 3T4AG 3BLBA 3CAZA 1O7DB 3CZSA 4EZZA 3RV0A 2LM0A 3BUBA 2EX3B 1DKZA 2YL9A 3FD9A 3VEAA 1I4DA 2ALWA 3F7WA 4HY9A 1R33A 4EZUA 4H8SA 3BUQA 3QA8A 2JNSA 4AZIA 4JN4A 2LXYA 2QFFA 2YI9A 2OW7A 3DPOA 3EJRA 3DDFA 4AVMA 1DKXA 3T46A 4IM0A 1E9VA 3DPPA 2Z8YA 3OHXM 2X3WA 3D4YA 4NSWA 4EZVA 3D51A 3VEBA 3ACOA 3BVUA 3B53X 3QWEA 1SU8A 4FZPA 3T49A 4ATMA 3RV1A 1O7DC 3BUPA 2YIBA 1GN9A 3CV5A 2FICA 2WYIA 5TKYA 4AZCB 5C5BB 2QKWA 1ZWWA 4AKVA 3DX3A 2GA9D 4JLCA 3T48A 1Y2OA 5FIGA 3SYVA 2OBLA 3BVXA 2F1BA 4IWQA 4FZOA 2JNKA 3D2EA 3UITA 2D4CA 2YL8A 2KHOA 4AZCA 5C5BA 3I2WA 1TQVA 2YLLA 3O3MB 1TQWA 1I49A 3PLTA 3D4ZA 2PMRA 2OW6A 4IWOA 4AZHA 4JNFA 4IM3A 3D50A 4R5KA 2O0I1 2ND1A 4R5GA 5KBPA 3ER8C 3O3OB 3OWGA 2X3VA 2EWFA 4R5JA 4AZBA 2MI7A 2OO2A 1OA0A 2WYHA 3C7NA 4R5IA 3M3WA 3B52X 3EJTA 4EZXA 3Q0KA 2N3KA 4AZ6A 3BVWA 3DDGA 1GNLA 4AZGA 4WPCA 2YKTA 2WINM 2YL6A 1HXKA 3CZNA 4IM2A 1R34A 2GAFD 3DX1A 1HWWA 1I4LA 4KIKB 4EZPA 1MJGA 2Z0OA 3I01A 3EJSA 2YI8A 2Q12A 2Z0VA 4EZYA 3B51X 1TQUA 4BNEA 1GNTA 1SU6A 3I04A 3GI7A 4AZ7A 1X03A 3ER9B 2FYVA 4EZSA 3LVTA 2C08A 2OBMA 3D52A 2F1AA 4DCNC 1I4TA 1X04A 1E1DA 3Q84A 3DPQA 1QWNA 4KIKA 4JWDA 3G9GA 4EZOA 4JNEA 2RAJA 2ELBA 2Q13A 4IW0A
chains in the Genus database with same CATH topology
3OK8A 4NQIA 4AKVA 2Z0NA 2V0OA 3QWEA 4ATMA 1I49A 3PLTA 4AVMA 2Z0OA 4DCNC 3M3WA 1I4TA 1I4DA 3HAHA 2EFKA 3ABHA 3HAIA 2Q12A 3LLLA 3Q0KA 4DYLA 4WPEA 1X04A 2D4CA 2Z0VA 4H8SA 3Q84A 2EFLA 2YKTA 4WPCA 2FICA 2X3WA 2X3VA 5C5BA 2RAKA 3QE6A 4NSWA 4FZSA 3HAJA 4BNEA 2RAIA 1URUA 1WDZA 3SOGA 3I2WA 3CAZA 3G9GA 1X03A 3DYTA 4I1QA 1Y2OA 2RAJA 3QNIA 2ELBA 3SYVA 5C5BB 2D1LA 2C08A 2X3XA 3ACOA 1I4LA 2Q13A 1ZWWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OK8 A;  4NQI A;  4AKV A;  2Z0N A;  2V0O A;  3QWE A;  4ATM A;  1I49 A;  3PLT A;  4AVM A;  2Z0O A;  4DCN C;  3M3W A;  1I4T A;  1I4D A;  3HAH A;  2EFK A;  3ABH A;  3HAI A;  2Q12 A;  3LLL A;  3Q0K A;  4DYL A;  4WPE A;  1X04 A;  2D4C A;  2Z0V A;  4H8S A;  3Q84 A;  2EFL A;  2YKT A;  4WPC A;  2FIC A;  2X3W A;  2X3V A;  5C5B A;  2RAK A;  3QE6 A;  4NSW A;  4FZS A;  3HAJ A;  4BNE A;  2RAI A;  1URU A;  1WDZ A;  3SOG A;  3I2W A;  3CAZ A;  3G9G A;  1X03 A;  3DYT A;  4I1Q A;  1Y2O A;  2RAJ A;  3QNI A;  2ELB A;  3SYV A;  5C5B B;  2D1L A;  2C08 A;  2X3X A;  3ACO A;  1I4L A;  2Q13 A;  1ZWW A; 
#chains in the Genus database with same CATH topology
 3OK8 A;  2V0O A;  4EZQ A;  3QNJ A;  3HAH A;  3ABH A;  3ERC C;  4F00 A;  3DX4 A;  1DKY A;  2X5C A;  4FM3 A;  2F7Q A;  4PO2 A;  4B9Q A;  5FLE X;  3A98 A;  3BVV A;  4H6I A;  2GF4 A;  2F7P A;  3QNI A;  4AZ5 A;  2D1L A;  2OZN B;  3L3P A;  4EZR A;  1QX1 A;  4M0M A;  1TQT A;  2EFK A;  3DX0 A;  3HAI A;  4NPH A;  4DYL A;  1LQ7 A;  1W9M A;  4E3C A;  1QWU A;  4JWI A;  3BVT A;  4EZT A;  3SOG A;  3DYT A;  1ZYL A;  4UDX X;  1PS3 A;  2YIA A;  2F7O A;  4F01 A;  4D8J A;  3LLL A;  3KDR A;  2EFL A;  1JQK A;  3VKH A;  4FZS A;  2RAI A;  1WDZ A;  4E81 A;  3BUI A;  1TQS A;  2PY6 A;  1U00 A;  3RPM A;  4EZW A;  1UPX A;  2YL5 A;  3KAW A;  1E2U A;  4H6H A;  1YWM A;  3BUD A;  2RT6 A;  2ZXQ A;  1OA1 A;  3CVR A;  4JL9 A;  3T47 A;  2YIV X;  4HR1 B;  4G6Q A;  5E84 A;  4EZN A;  2ND0 A;  4HYB A;  1HTY A;  3ZED A;  3HAJ A;  2F7R A;  1SU7 A;  3I39 X;  3O3N B;  3CKD A;  3LMF A;  4UDY X;  3EJQ A;  2NCZ A;  3EJP A;  4IWP A;  3QE6 A;  2YLA A;  4R5L A;  3L3O M;  1URU A;  3DX2 A;  3KAV A;  4I1Q A;  1SUF A;  2X3X A;  2QXL A;  3D2F A;  4NQI A;  2Z0N A;  1OAO A;  2F18 A;  3EJU A;  4JWE A;  4HR1 A;  1R5E A;  4WPE A;  2RAK A;  4JWC A;  3T4A G;  3BLB A;  3CAZ A;  1O7D B;  3CZS A;  4EZZ A;  3RV0 A;  2LM0 A;  3BUB A;  2EX3 B;  1DKZ A;  2YL9 A;  3FD9 A;  3VEA A;  1I4D A;  2ALW A;  3F7W A;  4HY9 A;  1R33 A;  4EZU A;  4H8S A;  3BUQ A;  3QA8 A;  2JNS A;  4AZI A;  4JN4 A;  2LXY A;  2QFF A;  2YI9 A;  2OW7 A;  3DPO A;  3EJR A;  3DDF A;  4AVM A;  1DKX A;  3T46 A;  4IM0 A;  1E9V A;  3DPP A;  2Z8Y A;  3OHX M;  2X3W A;  3D4Y A;  4NSW A;  4EZV A;  3D51 A;  3VEB A;  3ACO A;  3BVU A;  3B53 X;  3QWE A;  1SU8 A;  4FZP A;  3T49 A;  4ATM A;  3RV1 A;  1O7D C;  3BUP A;  2YIB A;  1GN9 A;  3CV5 A;  2FIC A;  2WYI A;  5TKY A;  4AZC B;  5C5B B;  2QKW A;  1ZWW A;  4AKV A;  3DX3 A;  2GA9 D;  4JLC A;  3T48 A;  1Y2O A;  5FIG A;  3SYV A;  2OBL A;  3BVX A;  2F1B A;  4IWQ A;  4FZO A;  2JNK A;  3D2E A;  3UIT A;  2D4C A;  2YL8 A;  2KHO A;  4AZC A;  5C5B A;  3I2W A;  1TQV A;  2YLL A;  3O3M B;  1TQW A;  1I49 A;  3PLT A;  3D4Z A;  2PMR A;  2OW6 A;  4IWO A;  4AZH A;  4JNF A;  4IM3 A;  3D50 A;  4R5K A;  2O0I 1;  2ND1 A;  4R5G A;  5KBP A;  3ER8 C;  3O3O B;  3OWG A;  2X3V A;  2EWF A;  4R5J A;  4AZB A;  2MI7 A;  2OO2 A;  1OA0 A;  2WYH A;  3C7N A;  4R5I A;  3M3W A;  3B52 X;  3EJT A;  4EZX A;  3Q0K A;  2N3K A;  4AZ6 A;  3BVW A;  3DDG A;  1GNL A;  4AZG A;  4WPC A;  2YKT A;  2WIN M;  2YL6 A;  1HXK A;  3CZN A;  4IM2 A;  1R34 A;  2GAF D;  3DX1 A;  1HWW A;  1I4L A;  4KIK B;  4EZP A;  1MJG A;  2Z0O A;  3I01 A;  3EJS A;  2YI8 A;  2Q12 A;  2Z0V A;  4EZY A;  3B51 X;  1TQU A;  4BNE A;  1GNT A;  1SU6 A;  3I04 A;  3GI7 A;  4AZ7 A;  1X03 A;  3ER9 B;  2FYV A;  4EZS A;  3LVT A;  2C08 A;  2OBM A;  3D52 A;  2F1A A;  4DCN C;  1I4T A;  1X04 A;  1E1D A;  3Q84 A;  3DPQ A;  1QWN A;  4KIK A;  4JWD A;  3G9G A;  4EZO A;  4JNE A;  2RAJ A;  2ELB A;  2Q13 A;  4IW0 A; 
#chains in the Genus database with same CATH homology
 3OK8 A;  4NQI A;  4AKV A;  2Z0N A;  2V0O A;  3QWE A;  4ATM A;  1I49 A;  3PLT A;  4AVM A;  2Z0O A;  4DCN C;  3M3W A;  1I4T A;  1I4D A;  3HAH A;  2EFK A;  3ABH A;  3HAI A;  2Q12 A;  3LLL A;  3Q0K A;  4DYL A;  4WPE A;  1X04 A;  2D4C A;  2Z0V A;  4H8S A;  3Q84 A;  2EFL A;  2YKT A;  4WPC A;  2FIC A;  2X3W A;  2X3V A;  5C5B A;  2RAK A;  3QE6 A;  4NSW A;  4FZS A;  3HAJ A;  4BNE A;  2RAI A;  1URU A;  1WDZ A;  3SOG A;  3I2W A;  3CAZ A;  3G9G A;  1X03 A;  3DYT A;  4I1Q A;  1Y2O A;  2RAJ A;  3QNI A;  2ELB A;  3SYV A;  5C5B B;  2D1L A;  2C08 A;  2X3X A;  3ACO A;  1I4L A;  2Q13 A;  1ZWW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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