3HAJA

Crystal structure of human pacsin2 f-bar domain (p212121 lattice)
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
286
structure length
286
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPGMAMNWPQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords human PACSIN2 F-BAR
publication title Molecular mechanism of membrane constriction and tubulation mediated by the F-BAR protein Pacsin/Syndapin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Endocytosis
total genus 107
structure length 286
sequence length 286
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-05-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 3hajA01
1WDZA 3LLLA 2C08A 3QE6A 4NSWA 1I49A 2EFKA 2ELBA 2RAKA 2X3VA 4DCNC 4AKVA 3ACOA 3HAJA 2X3WA 2V0OA 2Q13A 2EFLA 1X04A 2Z0VA 3QWEA 3HAIA 4FZSA 3M3WA 3SYVA 4NQIA 3CAZA 4AVMA 2D4CA 2FICA 3QNIA 4H8SA 4I1QA 1I4LA 1Y2OA 4WPEA 1ZWWA 3G9GA 3I2WA 4DYLA 2Z0OA 2Z0NA 5C5BA 4BNEA 1URUA 2X3XA 3SOGA 2RAIA 4WPCA 1I4DA 2YKTA 3ABHA 1I4TA 3DYTA 3HAHA 2Q12A 3Q0KA 5C5BB 3Q84A 3PLTA 2D1LA 4ATMA 1X03A 3OK8A 2RAJA
chains in the Genus database with same CATH superfamily
3BVXA 5FLEX 2F1AA 4R5GA 3RV0A 2MI7A 2YIVX 4H6IA 4I1QA 1LQ7A 1URUA 4EZSA 2YL5A 1I4DA 1YWMA 4IWQA 3ER9B 3SYVA 4KIKB 3M3WA 3CAZA 4H8SA 3QNIA 4G6QA 3DX4A 3OHXM 3Q0KA 4R5JA 2YL8A 4HR1B 4UDXX 2OBMA 4M0MA 1HTYA 4AZBA 3T48A 4EZNA 2Q13A 4IM0A 2Z0OA 4WPCA 1GNLA 2Q12A 2F7OA 1QWNA 3DX0A 4H6HA 2PMRA 2QKWA 1SUFA 4AZCB 3O3MB 2ELBA 2NCZA 3D50A 4AKVA 3D4YA 3L3OM 3BVVA 3DPPA 3VKHA 4R5KA 1I4LA 3BLBA 3I2WA 3DX3A 4BNEA 1O7DB 4E81A 2ND0A 3T49A 1O7DC 2YLAA 3D2FA 1I49A 3BUPA 3T47A 2RAKA 1ZYLA 4HYBA 4EZYA 2F7QA 4AZHA 5C5BA 4AVMA 2EWFA 2F7RA 3FD9A 4DYLA 4JWDA 1SU7A 4FM3A 2YI8A 3OK8A 4F00A 1OAOA 3ZEDA 2YIAA 2OW6A 4EZPA 3D52A 3KDRA 4JWCA 3VEBA 4HY9A 4AZIA 3KAVA 4KIKA 1R33A 3VEAA 5KBPA 2YIBA 4AZ5A 4EZRA 4EZTA 3QWEA 2Z8YA 2LXYA 1E9VA 4HR1A 4EZXA 3G9GA 3LVTA 5TKYA 3BVTA 2JNSA 3C7NA 2PY6A 1WDZA 3RV1A 2C08A 2WYIA 1PS3A 4AZ6A 2YL6A 3LMFA 5E84A 3DDFA 5FIGA 3F7WA 3CZSA 2Z0VA 3HAIA 4FZSA 4EZVA 1TQVA 4AZCA 4IWOA 4JWIA 3HAHA 2JNKA 3I04A 3D4ZA 3CKDA 3BVUA 4DCNC 3GI7A 3QNJA 2X3WA 2WINM 4JWEA 4WPEA 2QFFA 2OZNB 4JL9A 3D2EA 2X3XA 1W9MA 3B52X 4JLCA 3DPOA 2GF4A 3ACOA 3BUQA 2EFLA 2KHOA 3DX1A 2YLLA 4IW0A 4NQIA 2D4CA 2ALWA 1DKYA 4PO2A 3ER8C 3EJSA 1QX1A 1UPXA 3I39X 2X5CA 4B9QA 3DX2A 2YI9A 3I01A 4IWPA 2F7PA 1OA1A 1HXKA 2OW7A 2RT6A 5C5BB 1TQTA 1X03A 1OA0A 3QE6A 2OO2A 2GA9D 1SU8A 3HAJA 3EJUA 1TQUA 1GN9A 3CZNA 4NPHA 1E2UA 1Y2OA 3UITA 3EJQA 2Z0NA 1HWWA 4F01A 1JQKA 3KAWA 2QXLA 2RAIA 1R5EA 3Q84A 3PLTA 4ATMA 4EZZA 2RAJA 4R5IA 4JNFA 4JNEA 4IM3A 2OBLA 4FZOA 4FZPA 3EJRA 4AZGA 3T46A 3SOGA 1GNTA 2YKTA 3DYTA 2N3KA 3D51A 3EJTA 3B53X 4JN4A 2GAFD 3LLLA 1U00A 2ZXQA 3EJPA 2EFKA 3L3PA 3OWGA 4EZUA 1X04A 3RPMA 2ND1A 3O3OB 2O0I1 4EZOA 3ERCC 3DDGA 3DPQA 4D8JA 2YL9A 4IM2A 2EX3B 1R34A 3B51X 3BUIA 1DKXA 2V0OA 1QWUA 4R5LA 3O3NB 2F18A 1ZWWA 3BUDA 2WYHA 4UDYX 4AZ7A 1I4TA 2D1LA 3BUBA 3CV5A 1MJGA 4NSWA 3CVRA 1E1DA 2X3VA 3QA8A 3T4AG 1TQWA 1TQSA 2LM0A 3A98A 3BVWA 4EZQA 2FICA 1DKZA 4E3CA 4EZWA 1SU6A 2FYVA 3ABHA 2F1BA
chains in the Genus database with same CATH topology
1WDZA 3LLLA 2C08A 3QE6A 4NSWA 1I49A 2EFKA 2ELBA 2RAKA 2X3VA 4DCNC 4AKVA 3ACOA 3HAJA 2X3WA 2V0OA 2Q13A 2EFLA 1X04A 2Z0VA 3QWEA 3HAIA 4FZSA 3M3WA 3SYVA 4NQIA 3CAZA 4AVMA 2D4CA 2FICA 3QNIA 4H8SA 4I1QA 1I4LA 1Y2OA 4WPEA 1ZWWA 3G9GA 3I2WA 4DYLA 2Z0OA 2Z0NA 5C5BA 4BNEA 1URUA 2X3XA 3SOGA 2RAIA 4WPCA 1I4DA 2YKTA 3ABHA 1I4TA 3DYTA 3HAHA 2Q12A 3Q0KA 5C5BB 3Q84A 3PLTA 2D1LA 4ATMA 1X03A 3OK8A 2RAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WDZ A;  3LLL A;  2C08 A;  3QE6 A;  4NSW A;  1I49 A;  2EFK A;  2ELB A;  2RAK A;  2X3V A;  4DCN C;  4AKV A;  3ACO A;  3HAJ A;  2X3W A;  2V0O A;  2Q13 A;  2EFL A;  1X04 A;  2Z0V A;  3QWE A;  3HAI A;  4FZS A;  3M3W A;  3SYV A;  4NQI A;  3CAZ A;  4AVM A;  2D4C A;  2FIC A;  3QNI A;  4H8S A;  4I1Q A;  1I4L A;  1Y2O A;  4WPE A;  1ZWW A;  3G9G A;  3I2W A;  4DYL A;  2Z0O A;  2Z0N A;  5C5B A;  4BNE A;  1URU A;  2X3X A;  3SOG A;  2RAI A;  4WPC A;  1I4D A;  2YKT A;  3ABH A;  1I4T A;  3DYT A;  3HAH A;  2Q12 A;  3Q0K A;  5C5B B;  3Q84 A;  3PLT A;  2D1L A;  4ATM A;  1X03 A;  3OK8 A;  2RAJ A; 
#chains in the Genus database with same CATH topology
 3BVX A;  5FLE X;  2F1A A;  4R5G A;  3RV0 A;  2MI7 A;  2YIV X;  4H6I A;  4I1Q A;  1LQ7 A;  1URU A;  4EZS A;  2YL5 A;  1I4D A;  1YWM A;  4IWQ A;  3ER9 B;  3SYV A;  4KIK B;  3M3W A;  3CAZ A;  4H8S A;  3QNI A;  4G6Q A;  3DX4 A;  3OHX M;  3Q0K A;  4R5J A;  2YL8 A;  4HR1 B;  4UDX X;  2OBM A;  4M0M A;  1HTY A;  4AZB A;  3T48 A;  4EZN A;  2Q13 A;  4IM0 A;  2Z0O A;  4WPC A;  1GNL A;  2Q12 A;  2F7O A;  1QWN A;  3DX0 A;  4H6H A;  2PMR A;  2QKW A;  1SUF A;  4AZC B;  3O3M B;  2ELB A;  2NCZ A;  3D50 A;  4AKV A;  3D4Y A;  3L3O M;  3BVV A;  3DPP A;  3VKH A;  4R5K A;  1I4L A;  3BLB A;  3I2W A;  3DX3 A;  4BNE A;  1O7D B;  4E81 A;  2ND0 A;  3T49 A;  1O7D C;  2YLA A;  3D2F A;  1I49 A;  3BUP A;  3T47 A;  2RAK A;  1ZYL A;  4HYB A;  4EZY A;  2F7Q A;  4AZH A;  5C5B A;  4AVM A;  2EWF A;  2F7R A;  3FD9 A;  4DYL A;  4JWD A;  1SU7 A;  4FM3 A;  2YI8 A;  3OK8 A;  4F00 A;  1OAO A;  3ZED A;  2YIA A;  2OW6 A;  4EZP A;  3D52 A;  3KDR A;  4JWC A;  3VEB A;  4HY9 A;  4AZI A;  3KAV A;  4KIK A;  1R33 A;  3VEA A;  5KBP A;  2YIB A;  4AZ5 A;  4EZR A;  4EZT A;  3QWE A;  2Z8Y A;  2LXY A;  1E9V A;  4HR1 A;  4EZX A;  3G9G A;  3LVT A;  5TKY A;  3BVT A;  2JNS A;  3C7N A;  2PY6 A;  1WDZ A;  3RV1 A;  2C08 A;  2WYI A;  1PS3 A;  4AZ6 A;  2YL6 A;  3LMF A;  5E84 A;  3DDF A;  5FIG A;  3F7W A;  3CZS A;  2Z0V A;  3HAI A;  4FZS A;  4EZV A;  1TQV A;  4AZC A;  4IWO A;  4JWI A;  3HAH A;  2JNK A;  3I04 A;  3D4Z A;  3CKD A;  3BVU A;  4DCN C;  3GI7 A;  3QNJ A;  2X3W A;  2WIN M;  4JWE A;  4WPE A;  2QFF A;  2OZN B;  4JL9 A;  3D2E A;  2X3X A;  1W9M A;  3B52 X;  4JLC A;  3DPO A;  2GF4 A;  3ACO A;  3BUQ A;  2EFL A;  2KHO A;  3DX1 A;  2YLL A;  4IW0 A;  4NQI A;  2D4C A;  2ALW A;  1DKY A;  4PO2 A;  3ER8 C;  3EJS A;  1QX1 A;  1UPX A;  3I39 X;  2X5C A;  4B9Q A;  3DX2 A;  2YI9 A;  3I01 A;  4IWP A;  2F7P A;  1OA1 A;  1HXK A;  2OW7 A;  2RT6 A;  5C5B B;  1TQT A;  1X03 A;  1OA0 A;  3QE6 A;  2OO2 A;  2GA9 D;  1SU8 A;  3HAJ A;  3EJU A;  1TQU A;  1GN9 A;  3CZN A;  4NPH A;  1E2U A;  1Y2O A;  3UIT A;  3EJQ A;  2Z0N A;  1HWW A;  4F01 A;  1JQK A;  3KAW A;  2QXL A;  2RAI A;  1R5E A;  3Q84 A;  3PLT A;  4ATM A;  4EZZ A;  2RAJ A;  4R5I A;  4JNF A;  4JNE A;  4IM3 A;  2OBL A;  4FZO A;  4FZP A;  3EJR A;  4AZG A;  3T46 A;  3SOG A;  1GNT A;  2YKT A;  3DYT A;  2N3K A;  3D51 A;  3EJT A;  3B53 X;  4JN4 A;  2GAF D;  3LLL A;  1U00 A;  2ZXQ A;  3EJP A;  2EFK A;  3L3P A;  3OWG A;  4EZU A;  1X04 A;  3RPM A;  2ND1 A;  3O3O B;  2O0I 1;  4EZO A;  3ERC C;  3DDG A;  3DPQ A;  4D8J A;  2YL9 A;  4IM2 A;  2EX3 B;  1R34 A;  3B51 X;  3BUI A;  1DKX A;  2V0O A;  1QWU A;  4R5L A;  3O3N B;  2F18 A;  1ZWW A;  3BUD A;  2WYH A;  4UDY X;  4AZ7 A;  1I4T A;  2D1L A;  3BUB A;  3CV5 A;  1MJG A;  4NSW A;  3CVR A;  1E1D A;  2X3V A;  3QA8 A;  3T4A G;  1TQW A;  1TQS A;  2LM0 A;  3A98 A;  3BVW A;  4EZQ A;  2FIC A;  1DKZ A;  4E3C A;  4EZW A;  1SU6 A;  2FYV A;  3ABH A;  2F1B A; 
#chains in the Genus database with same CATH homology
 1WDZ A;  3LLL A;  2C08 A;  3QE6 A;  4NSW A;  1I49 A;  2EFK A;  2ELB A;  2RAK A;  2X3V A;  4DCN C;  4AKV A;  3ACO A;  3HAJ A;  2X3W A;  2V0O A;  2Q13 A;  2EFL A;  1X04 A;  2Z0V A;  3QWE A;  3HAI A;  4FZS A;  3M3W A;  3SYV A;  4NQI A;  3CAZ A;  4AVM A;  2D4C A;  2FIC A;  3QNI A;  4H8S A;  4I1Q A;  1I4L A;  1Y2O A;  4WPE A;  1ZWW A;  3G9G A;  3I2W A;  4DYL A;  2Z0O A;  2Z0N A;  5C5B A;  4BNE A;  1URU A;  2X3X A;  3SOG A;  2RAI A;  4WPC A;  1I4D A;  2YKT A;  3ABH A;  1I4T A;  3DYT A;  3HAH A;  2Q12 A;  3Q0K A;  5C5B B;  3Q84 A;  3PLT A;  2D1L A;  4ATM A;  1X03 A;  3OK8 A;  2RAJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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