2C08A

Rat endophilin a1 bar domain
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
204
structure length
204
Chain Sequence
EGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDMEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Endophilin N-Bar Domain-Mediated Membrane Curvature.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords SH3-CONTAINING GRB2-LIKE PROTEIN 2
total genus 73
structure length 204
sequence length 204
ec nomenclature ec 2.3.1.-:
pdb deposition date 2005-08-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2c08A00
3QWEA 3LLLA 4DCNC 4DYLA 2Z0VA 1WDZA 3QE6A 2FICA 1I4TA 1I4LA 2X3VA 3ACOA 3PLTA 3DYTA 3Q84A 3SYVA 3M3WA 3ABHA 3HAIA 1X03A 2X3XA 1X04A 4WPCA 3CAZA 2D4CA 2D1LA 1ZWWA 3HAHA 2EFLA 1Y2OA 4I1QA 1I4DA 2YKTA 3SOGA 3I2WA 2C08A 2EFKA 3HAJA 4H8SA 3OK8A 1URUA 2Q13A 2X3WA 2RAIA 2RAKA 5C5BB 2ELBA 1I49A 4ATMA 4FZSA 4AKVA 4NQIA 4AVMA 4NSWA 2Q12A 2RAJA 2Z0NA 4WPEA 5C5BA 2Z0OA 3QNIA 3G9GA 2V0OA 4BNEA 3Q0KA
chains in the Genus database with same CATH superfamily
4EZYA 3CKDA 4IM2A 2X3VA 3EJRA 3B53X 4I1QA 1GNTA 1R33A 3I39X 4IWPA 3D50A 1TQSA 4JNFA 4DCNC 4R5LA 4IM0A 2F18A 5E84A 3GI7A 1ZWWA 1Y2OA 1I4DA 4HR1B 3SOGA 2EFKA 3HAJA 2ALWA 2Q13A 4JL9A 3LMFA 2EX3B 4H6HA 2N3KA 3D4ZA 4JLCA 4AZCB 1TQUA 4G6QA 3DYTA 4WPCA 4EZUA 1OA1A 4JWEA 4HR1A 3D51A 2Z0NA 1E9VA 1HWWA 2YIAA 3O3OB 2FICA 1E1DA 3VKHA 1PS3A 4AZGA 2D1LA 3D4YA 1LQ7A 3BUBA 3I2WA 2QXLA 4JNEA 1YWMA 4HY9A 4AKVA 4UDYX 3RV1A 3KDRA 3T46A 3DPOA 3OHXM 2ND1A 3RV0A 4EZNA 1W9MA 2X3XA 1HTYA 4EZTA 3D52A 4H6IA 2YI8A 4NSWA 3BVUA 3QNIA 1ZYLA 2FYVA 3O3NB 3A98A 3BUQA 3DPPA 4EZWA 1UPXA 4E3CA 3PLTA 1QX1A 2F7RA 5FLEX 3DDGA 2C08A 3T48A 2ELBA 3ERCC 2ZXQA 4JN4A 3HAIA 2V0OA 4B9QA 3BUIA 3SYVA 4JWCA 4R5GA 2F1AA 1GNLA 2YL9A 2YKTA 3KAWA 3BUPA 2OW7A 3BLBA 1OAOA 1O7DC 3DX0A 3Q0KA 2YI9A 2WYIA 3BVXA 3FD9A 2X5CA 3HAHA 3CZSA 4PO2A 2YIVX 3KAVA 2LXYA 2JNSA 4FM3A 1I49A 3C7NA 4NQIA 1DKYA 2RAJA 2RT6A 4IM3A 3QWEA 3DX3A 4AZCA 2O0I1 4M0MA 2D4CA 3CV5A 1QWUA 2WYHA 1O7DB 2OO2A 3BVTA 3ER8C 4R5JA 2Z0OA 3QA8A 3B52X 2QFFA 3I01A 3LLLA 4JWIA 2JNKA 1E2UA 2Z0VA 3EJTA 2GA9D 3M3WA 2LM0A 4H8SA 4UDXX 2OBMA 1HXKA 2F7OA 4ATMA 4R5KA 1JQKA 3G9GA 2WINM 3ZEDA 3CZNA 4EZOA 3EJPA 2QKWA 3QE6A 1I4TA 2ND0A 5TKYA 4AZ7A 2YIBA 4FZPA 4EZXA 3CAZA 2GF4A 4F00A 3OK8A 2YL5A 3B51X 1SUFA 3DPQA 3I04A 1DKXA 3DDFA 4IW0A 4DYLA 1WDZA 1SU8A 3T47A 4KIKB 3ER9B 3ACOA 3D2EA 3Q84A 2YL8A 2YLAA 2EFLA 1R5EA 1URUA 2RAKA 4NPHA 2KHOA 3BVWA 4AZ6A 2MI7A 2OBLA 4EZRA 1TQWA 1DKZA 2F1BA 2F7PA 4E81A 3O3MB 4KIKA 1X03A 3BUDA 4EZQA 3DX1A 5C5BB 2NCZA 2YL6A 4FZSA 4AVMA 4HYBA 3T49A 3RPMA 3LVTA 4EZPA 1GN9A 2Z8YA 1X04A 2PY6A 3D2FA 4F01A 4AZHA 2GAFD 3OWGA 2X3WA 4EZVA 2RAIA 4EZZA 2OZNB 5C5BA 4BNEA 3T4AG 1R34A 3EJQA 3DX4A 4JWDA 1U00A 3VEBA 1I4LA 2F7QA 5KBPA 4AZ5A 3QNJA 1SU6A 4AZBA 3VEAA 3F7WA 4IWQA 4AZIA 2Q12A 3CVRA 2OW6A 3L3PA 1MJGA 2YLLA 5FIGA 3BVVA 1OA0A 2EWFA 4IWOA 4EZSA 1QWNA 3ABHA 3L3OM 1TQTA 4FZOA 3EJUA 2PMRA 3UITA 4R5IA 1SU7A 3EJSA 4WPEA 4D8JA 3DX2A 1TQVA
chains in the Genus database with same CATH topology
3QWEA 3LLLA 4DCNC 4DYLA 2Z0VA 1WDZA 3QE6A 2FICA 1I4TA 1I4LA 2X3VA 3ACOA 3PLTA 3DYTA 3Q84A 3SYVA 3M3WA 3ABHA 3HAIA 1X03A 2X3XA 1X04A 4WPCA 3CAZA 2D4CA 2D1LA 1ZWWA 3HAHA 2EFLA 1Y2OA 4I1QA 1I4DA 2YKTA 3SOGA 3I2WA 2C08A 2EFKA 3HAJA 4H8SA 3OK8A 1URUA 2Q13A 2X3WA 2RAIA 2RAKA 5C5BB 2ELBA 1I49A 4ATMA 4FZSA 4AKVA 4NQIA 4AVMA 4NSWA 2Q12A 2RAJA 2Z0NA 4WPEA 5C5BA 2Z0OA 3QNIA 3G9GA 2V0OA 4BNEA 3Q0KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QWE A;  3LLL A;  4DCN C;  4DYL A;  2Z0V A;  1WDZ A;  3QE6 A;  2FIC A;  1I4T A;  1I4L A;  2X3V A;  3ACO A;  3PLT A;  3DYT A;  3Q84 A;  3SYV A;  3M3W A;  3ABH A;  3HAI A;  1X03 A;  2X3X A;  1X04 A;  4WPC A;  3CAZ A;  2D4C A;  2D1L A;  1ZWW A;  3HAH A;  2EFL A;  1Y2O A;  4I1Q A;  1I4D A;  2YKT A;  3SOG A;  3I2W A;  2C08 A;  2EFK A;  3HAJ A;  4H8S A;  3OK8 A;  1URU A;  2Q13 A;  2X3W A;  2RAI A;  2RAK A;  5C5B B;  2ELB A;  1I49 A;  4ATM A;  4FZS A;  4AKV A;  4NQI A;  4AVM A;  4NSW A;  2Q12 A;  2RAJ A;  2Z0N A;  4WPE A;  5C5B A;  2Z0O A;  3QNI A;  3G9G A;  2V0O A;  4BNE A;  3Q0K A; 
#chains in the Genus database with same CATH topology
 4EZY A;  3CKD A;  4IM2 A;  2X3V A;  3EJR A;  3B53 X;  4I1Q A;  1GNT A;  1R33 A;  3I39 X;  4IWP A;  3D50 A;  1TQS A;  4JNF A;  4DCN C;  4R5L A;  4IM0 A;  2F18 A;  5E84 A;  3GI7 A;  1ZWW A;  1Y2O A;  1I4D A;  4HR1 B;  3SOG A;  2EFK A;  3HAJ A;  2ALW A;  2Q13 A;  4JL9 A;  3LMF A;  2EX3 B;  4H6H A;  2N3K A;  3D4Z A;  4JLC A;  4AZC B;  1TQU A;  4G6Q A;  3DYT A;  4WPC A;  4EZU A;  1OA1 A;  4JWE A;  4HR1 A;  3D51 A;  2Z0N A;  1E9V A;  1HWW A;  2YIA A;  3O3O B;  2FIC A;  1E1D A;  3VKH A;  1PS3 A;  4AZG A;  2D1L A;  3D4Y A;  1LQ7 A;  3BUB A;  3I2W A;  2QXL A;  4JNE A;  1YWM A;  4HY9 A;  4AKV A;  4UDY X;  3RV1 A;  3KDR A;  3T46 A;  3DPO A;  3OHX M;  2ND1 A;  3RV0 A;  4EZN A;  1W9M A;  2X3X A;  1HTY A;  4EZT A;  3D52 A;  4H6I A;  2YI8 A;  4NSW A;  3BVU A;  3QNI A;  1ZYL A;  2FYV A;  3O3N B;  3A98 A;  3BUQ A;  3DPP A;  4EZW A;  1UPX A;  4E3C A;  3PLT A;  1QX1 A;  2F7R A;  5FLE X;  3DDG A;  2C08 A;  3T48 A;  2ELB A;  3ERC C;  2ZXQ A;  4JN4 A;  3HAI A;  2V0O A;  4B9Q A;  3BUI A;  3SYV A;  4JWC A;  4R5G A;  2F1A A;  1GNL A;  2YL9 A;  2YKT A;  3KAW A;  3BUP A;  2OW7 A;  3BLB A;  1OAO A;  1O7D C;  3DX0 A;  3Q0K A;  2YI9 A;  2WYI A;  3BVX A;  3FD9 A;  2X5C A;  3HAH A;  3CZS A;  4PO2 A;  2YIV X;  3KAV A;  2LXY A;  2JNS A;  4FM3 A;  1I49 A;  3C7N A;  4NQI A;  1DKY A;  2RAJ A;  2RT6 A;  4IM3 A;  3QWE A;  3DX3 A;  4AZC A;  2O0I 1;  4M0M A;  2D4C A;  3CV5 A;  1QWU A;  2WYH A;  1O7D B;  2OO2 A;  3BVT A;  3ER8 C;  4R5J A;  2Z0O A;  3QA8 A;  3B52 X;  2QFF A;  3I01 A;  3LLL A;  4JWI A;  2JNK A;  1E2U A;  2Z0V A;  3EJT A;  2GA9 D;  3M3W A;  2LM0 A;  4H8S A;  4UDX X;  2OBM A;  1HXK A;  2F7O A;  4ATM A;  4R5K A;  1JQK A;  3G9G A;  2WIN M;  3ZED A;  3CZN A;  4EZO A;  3EJP A;  2QKW A;  3QE6 A;  1I4T A;  2ND0 A;  5TKY A;  4AZ7 A;  2YIB A;  4FZP A;  4EZX A;  3CAZ A;  2GF4 A;  4F00 A;  3OK8 A;  2YL5 A;  3B51 X;  1SUF A;  3DPQ A;  3I04 A;  1DKX A;  3DDF A;  4IW0 A;  4DYL A;  1WDZ A;  1SU8 A;  3T47 A;  4KIK B;  3ER9 B;  3ACO A;  3D2E A;  3Q84 A;  2YL8 A;  2YLA A;  2EFL A;  1R5E A;  1URU A;  2RAK A;  4NPH A;  2KHO A;  3BVW A;  4AZ6 A;  2MI7 A;  2OBL A;  4EZR A;  1TQW A;  1DKZ A;  2F1B A;  2F7P A;  4E81 A;  3O3M B;  4KIK A;  1X03 A;  3BUD A;  4EZQ A;  3DX1 A;  5C5B B;  2NCZ A;  2YL6 A;  4FZS A;  4AVM A;  4HYB A;  3T49 A;  3RPM A;  3LVT A;  4EZP A;  1GN9 A;  2Z8Y A;  1X04 A;  2PY6 A;  3D2F A;  4F01 A;  4AZH A;  2GAF D;  3OWG A;  2X3W A;  4EZV A;  2RAI A;  4EZZ A;  2OZN B;  5C5B A;  4BNE A;  3T4A G;  1R34 A;  3EJQ A;  3DX4 A;  4JWD A;  1U00 A;  3VEB A;  1I4L A;  2F7Q A;  5KBP A;  4AZ5 A;  3QNJ A;  1SU6 A;  4AZB A;  3VEA A;  3F7W A;  4IWQ A;  4AZI A;  2Q12 A;  3CVR A;  2OW6 A;  3L3P A;  1MJG A;  2YLL A;  5FIG A;  3BVV A;  1OA0 A;  2EWF A;  4IWO A;  4EZS A;  1QWN A;  3ABH A;  3L3O M;  1TQT A;  4FZO A;  3EJU A;  2PMR A;  3UIT A;  4R5I A;  1SU7 A;  3EJS A;  4WPE A;  4D8J A;  3DX2 A;  1TQV A; 
#chains in the Genus database with same CATH homology
 3QWE A;  3LLL A;  4DCN C;  4DYL A;  2Z0V A;  1WDZ A;  3QE6 A;  2FIC A;  1I4T A;  1I4L A;  2X3V A;  3ACO A;  3PLT A;  3DYT A;  3Q84 A;  3SYV A;  3M3W A;  3ABH A;  3HAI A;  1X03 A;  2X3X A;  1X04 A;  4WPC A;  3CAZ A;  2D4C A;  2D1L A;  1ZWW A;  3HAH A;  2EFL A;  1Y2O A;  4I1Q A;  1I4D A;  2YKT A;  3SOG A;  3I2W A;  2C08 A;  2EFK A;  3HAJ A;  4H8S A;  3OK8 A;  1URU A;  2Q13 A;  2X3W A;  2RAI A;  2RAK A;  5C5B B;  2ELB A;  1I49 A;  4ATM A;  4FZS A;  4AKV A;  4NQI A;  4AVM A;  4NSW A;  2Q12 A;  2RAJ A;  2Z0N A;  4WPE A;  5C5B A;  2Z0O A;  3QNI A;  3G9G A;  2V0O A;  4BNE A;  3Q0K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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