1WDZA

Crystal structure of rcb domain of irsp53
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
231
structure length
231
Chain Sequence
SLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQGVDS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of RCB domain of IRSp53
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords insulin receptor substrate p53
total genus 112
structure length 231
sequence length 231
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-05-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 1wdzA00
3Q84A 3CAZA 4H8SA 4WPCA 4WPEA 1I4TA 2Q12A 4DCNC 3HAJA 2Q13A 1I49A 3HAIA 2X3WA 1ZWWA 3QNIA 1I4LA 3DYTA 4I1QA 3OK8A 4AKVA 4NSWA 1X04A 3PLTA 1I4DA 4DYLA 2D4CA 1X03A 3Q0KA 2YKTA 3QWEA 2EFLA 3I2WA 3LLLA 3ACOA 2V0OA 3ABHA 4FZSA 2FICA 3G9GA 5C5BB 1URUA 2X3XA 2Z0OA 1Y2OA 2Z0NA 2RAJA 3M3WA 4AVMA 4BNEA 1WDZA 2Z0VA 3SYVA 3SOGA 3HAHA 4ATMA 2C08A 5C5BA 2EFKA 2ELBA 2X3VA 3QE6A 2RAIA 4NQIA 2D1LA 2RAKA
chains in the Genus database with same CATH superfamily
3VEAA 2NCZA 2GF4A 3HAIA 3CKDA 4R5IA 2OZNB 3KAVA 3BUIA 2YIVX 3BVWA 5FIGA 1SUFA 1TQTA 3BUQA 3DPPA 3ABHA 3D4ZA 1U00A 2OW6A 2YIAA 4JNFA 2PMRA 3GI7A 2LXYA 1QWUA 2EFKA 4EZWA 4D8JA 2D1LA 1GN9A 4WPCA 4AZBA 2GA9D 2YL8A 1SU8A 4AZHA 1X03A 2OW7A 3BVTA 3EJSA 2ND0A 3DX2A 2Z0OA 3M3WA 2QXLA 2Z0VA 4HY9A 4E81A 2WINM 2MI7A 3DYTA 3OK8A 5C5BB 1DKYA 4H8SA 2YIBA 4B9QA 1R5EA 1PS3A 2F7PA 3T4AG 3Q0KA 1HWWA 3ZEDA 2F7RA 2C08A 4JWIA 5E84A 3O3OB 3T49A 3PLTA 2YLLA 3LLLA 3QNJA 1O7DC 1ZYLA 3SOGA 1OAOA 4ATMA 5KBPA 2RAKA 2Q12A 2YL6A 3F7WA 1I4LA 2RT6A 4AZCA 4IM3A 2D4CA 3QWEA 4FZSA 3QA8A 3D51A 2Z0NA 2RAJA 4KIKA 3T48A 3D2FA 5FLEX 2O0I1 4EZQA 4EZZA 2F18A 3RV1A 2OO2A 3DDGA 4EZNA 3KDRA 1DKXA 1HXKA 2YI9A 4AZGA 1R33A 1O7DB 1GNTA 4F00A 1I4TA 1JQKA 4EZOA 4IW0A 3O3NB 4G6QA 3D2EA 3I39X 4JWCA 1E2UA 4R5LA 2FICA 1SU7A 4FZOA 3ER9B 2YLAA 4JWEA 2ELBA 3B53X 1HTYA 4NQIA 4H6IA 3B51X 3ER8C 4AZCB 4WPEA 3BVVA 4DCNC 3ERCC 1YWMA 1R34A 4F01A 2EFLA 4EZVA 4FM3A 4KIKB 2V0OA 3B52X 3T46A 3T47A 2X5CA 3Q84A 1QX1A 2EWFA 1ZWWA 4E3CA 4IWPA 4DYLA 1E9VA 3D4YA 3I2WA 3CZNA 4JLCA 2YL5A 3DX1A 3DPOA 4JNEA 4M0MA 2LM0A 1LQ7A 1DKZA 2ND1A 4EZUA 2F7OA 4FZPA 3EJPA 4HR1A 3OHXM 4EZRA 4JN4A 2KHOA 3CZSA 4AZIA 4UDYX 1OA1A 1URUA 1W9MA 1TQVA 3HAHA 5C5BA 4EZSA 3CV5A 3OWGA 4AZ6A 3DDFA 3HAJA 4HYBA 2F1AA 3LVTA 3EJQA 4IWOA 3RPMA 4AKVA 4R5GA 1I4DA 3KAWA 3BUPA 4UDXX 3I04A 2X3XA 1WDZA 3A98A 2OBLA 4NPHA 2PY6A 2RAIA 1TQUA 3EJRA 1SU6A 2Q13A 5TKYA 3BLBA 2X3WA 4EZTA 2ALWA 3VEBA 2GAFD 1X04A 3ACOA 4AZ5A 3BVUA 4EZPA 3LMFA 4JL9A 3D50A 4EZXA 3QE6A 4HR1B 2QKWA 1TQSA 3O3MB 3QNIA 4R5JA 4NSWA 3BVXA 4PO2A 2YKTA 3EJUA 1TQWA 3DX3A 3FD9A 4BNEA 2YL9A 2WYHA 2X3VA 3EJTA 4AZ7A 3UITA 3C7NA 2WYIA 1I49A 2FYVA 2OBMA 3RV0A 2YI8A 3VKHA 1OA0A 2EX3B 4IM0A 2F7QA 2Z8YA 1Y2OA 3I01A 3CVRA 2QFFA 1GNLA 1MJGA 3BUBA 2N3KA 3DX0A 4EZYA 3CAZA 4H6HA 2JNSA 2ZXQA 3L3OM 4R5KA 3L3PA 1E1DA 1UPXA 4I1QA 1QWNA 3BUDA 3DPQA 4IWQA 4IM2A 3G9GA 3D52A 2JNKA 4JWDA 4AVMA 3SYVA 2F1BA 3DX4A
chains in the Genus database with same CATH topology
3Q84A 3CAZA 4H8SA 4WPCA 4WPEA 1I4TA 2Q12A 4DCNC 3HAJA 2Q13A 1I49A 3HAIA 2X3WA 1ZWWA 3QNIA 1I4LA 3DYTA 4I1QA 3OK8A 4AKVA 4NSWA 1X04A 3PLTA 1I4DA 4DYLA 2D4CA 1X03A 3Q0KA 2YKTA 3QWEA 2EFLA 3I2WA 3LLLA 3ACOA 2V0OA 3ABHA 4FZSA 2FICA 3G9GA 5C5BB 1URUA 2X3XA 2Z0OA 1Y2OA 2Z0NA 2RAJA 3M3WA 4AVMA 4BNEA 1WDZA 2Z0VA 3SYVA 3SOGA 3HAHA 4ATMA 2C08A 5C5BA 2EFKA 2ELBA 2X3VA 3QE6A 2RAIA 4NQIA 2D1LA 2RAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q84 A;  3CAZ A;  4H8S A;  4WPC A;  4WPE A;  1I4T A;  2Q12 A;  4DCN C;  3HAJ A;  2Q13 A;  1I49 A;  3HAI A;  2X3W A;  1ZWW A;  3QNI A;  1I4L A;  3DYT A;  4I1Q A;  3OK8 A;  4AKV A;  4NSW A;  1X04 A;  3PLT A;  1I4D A;  4DYL A;  2D4C A;  1X03 A;  3Q0K A;  2YKT A;  3QWE A;  2EFL A;  3I2W A;  3LLL A;  3ACO A;  2V0O A;  3ABH A;  4FZS A;  2FIC A;  3G9G A;  5C5B B;  1URU A;  2X3X A;  2Z0O A;  1Y2O A;  2Z0N A;  2RAJ A;  3M3W A;  4AVM A;  4BNE A;  1WDZ A;  2Z0V A;  3SYV A;  3SOG A;  3HAH A;  4ATM A;  2C08 A;  5C5B A;  2EFK A;  2ELB A;  2X3V A;  3QE6 A;  2RAI A;  4NQI A;  2D1L A;  2RAK A; 
#chains in the Genus database with same CATH topology
 3VEA A;  2NCZ A;  2GF4 A;  3HAI A;  3CKD A;  4R5I A;  2OZN B;  3KAV A;  3BUI A;  2YIV X;  3BVW A;  5FIG A;  1SUF A;  1TQT A;  3BUQ A;  3DPP A;  3ABH A;  3D4Z A;  1U00 A;  2OW6 A;  2YIA A;  4JNF A;  2PMR A;  3GI7 A;  2LXY A;  1QWU A;  2EFK A;  4EZW A;  4D8J A;  2D1L A;  1GN9 A;  4WPC A;  4AZB A;  2GA9 D;  2YL8 A;  1SU8 A;  4AZH A;  1X03 A;  2OW7 A;  3BVT A;  3EJS A;  2ND0 A;  3DX2 A;  2Z0O A;  3M3W A;  2QXL A;  2Z0V A;  4HY9 A;  4E81 A;  2WIN M;  2MI7 A;  3DYT A;  3OK8 A;  5C5B B;  1DKY A;  4H8S A;  2YIB A;  4B9Q A;  1R5E A;  1PS3 A;  2F7P A;  3T4A G;  3Q0K A;  1HWW A;  3ZED A;  2F7R A;  2C08 A;  4JWI A;  5E84 A;  3O3O B;  3T49 A;  3PLT A;  2YLL A;  3LLL A;  3QNJ A;  1O7D C;  1ZYL A;  3SOG A;  1OAO A;  4ATM A;  5KBP A;  2RAK A;  2Q12 A;  2YL6 A;  3F7W A;  1I4L A;  2RT6 A;  4AZC A;  4IM3 A;  2D4C A;  3QWE A;  4FZS A;  3QA8 A;  3D51 A;  2Z0N A;  2RAJ A;  4KIK A;  3T48 A;  3D2F A;  5FLE X;  2O0I 1;  4EZQ A;  4EZZ A;  2F18 A;  3RV1 A;  2OO2 A;  3DDG A;  4EZN A;  3KDR A;  1DKX A;  1HXK A;  2YI9 A;  4AZG A;  1R33 A;  1O7D B;  1GNT A;  4F00 A;  1I4T A;  1JQK A;  4EZO A;  4IW0 A;  3O3N B;  4G6Q A;  3D2E A;  3I39 X;  4JWC A;  1E2U A;  4R5L A;  2FIC A;  1SU7 A;  4FZO A;  3ER9 B;  2YLA A;  4JWE A;  2ELB A;  3B53 X;  1HTY A;  4NQI A;  4H6I A;  3B51 X;  3ER8 C;  4AZC B;  4WPE A;  3BVV A;  4DCN C;  3ERC C;  1YWM A;  1R34 A;  4F01 A;  2EFL A;  4EZV A;  4FM3 A;  4KIK B;  2V0O A;  3B52 X;  3T46 A;  3T47 A;  2X5C A;  3Q84 A;  1QX1 A;  2EWF A;  1ZWW A;  4E3C A;  4IWP A;  4DYL A;  1E9V A;  3D4Y A;  3I2W A;  3CZN A;  4JLC A;  2YL5 A;  3DX1 A;  3DPO A;  4JNE A;  4M0M A;  2LM0 A;  1LQ7 A;  1DKZ A;  2ND1 A;  4EZU A;  2F7O A;  4FZP A;  3EJP A;  4HR1 A;  3OHX M;  4EZR A;  4JN4 A;  2KHO A;  3CZS A;  4AZI A;  4UDY X;  1OA1 A;  1URU A;  1W9M A;  1TQV A;  3HAH A;  5C5B A;  4EZS A;  3CV5 A;  3OWG A;  4AZ6 A;  3DDF A;  3HAJ A;  4HYB A;  2F1A A;  3LVT A;  3EJQ A;  4IWO A;  3RPM A;  4AKV A;  4R5G A;  1I4D A;  3KAW A;  3BUP A;  4UDX X;  3I04 A;  2X3X A;  1WDZ A;  3A98 A;  2OBL A;  4NPH A;  2PY6 A;  2RAI A;  1TQU A;  3EJR A;  1SU6 A;  2Q13 A;  5TKY A;  3BLB A;  2X3W A;  4EZT A;  2ALW A;  3VEB A;  2GAF D;  1X04 A;  3ACO A;  4AZ5 A;  3BVU A;  4EZP A;  3LMF A;  4JL9 A;  3D50 A;  4EZX A;  3QE6 A;  4HR1 B;  2QKW A;  1TQS A;  3O3M B;  3QNI A;  4R5J A;  4NSW A;  3BVX A;  4PO2 A;  2YKT A;  3EJU A;  1TQW A;  3DX3 A;  3FD9 A;  4BNE A;  2YL9 A;  2WYH A;  2X3V A;  3EJT A;  4AZ7 A;  3UIT A;  3C7N A;  2WYI A;  1I49 A;  2FYV A;  2OBM A;  3RV0 A;  2YI8 A;  3VKH A;  1OA0 A;  2EX3 B;  4IM0 A;  2F7Q A;  2Z8Y A;  1Y2O A;  3I01 A;  3CVR A;  2QFF A;  1GNL A;  1MJG A;  3BUB A;  2N3K A;  3DX0 A;  4EZY A;  3CAZ A;  4H6H A;  2JNS A;  2ZXQ A;  3L3O M;  4R5K A;  3L3P A;  1E1D A;  1UPX A;  4I1Q A;  1QWN A;  3BUD A;  3DPQ A;  4IWQ A;  4IM2 A;  3G9G A;  3D52 A;  2JNK A;  4JWD A;  4AVM A;  3SYV A;  2F1B A;  3DX4 A; 
#chains in the Genus database with same CATH homology
 3Q84 A;  3CAZ A;  4H8S A;  4WPC A;  4WPE A;  1I4T A;  2Q12 A;  4DCN C;  3HAJ A;  2Q13 A;  1I49 A;  3HAI A;  2X3W A;  1ZWW A;  3QNI A;  1I4L A;  3DYT A;  4I1Q A;  3OK8 A;  4AKV A;  4NSW A;  1X04 A;  3PLT A;  1I4D A;  4DYL A;  2D4C A;  1X03 A;  3Q0K A;  2YKT A;  3QWE A;  2EFL A;  3I2W A;  3LLL A;  3ACO A;  2V0O A;  3ABH A;  4FZS A;  2FIC A;  3G9G A;  5C5B B;  1URU A;  2X3X A;  2Z0O A;  1Y2O A;  2Z0N A;  2RAJ A;  3M3W A;  4AVM A;  4BNE A;  1WDZ A;  2Z0V A;  3SYV A;  3SOG A;  3HAH A;  4ATM A;  2C08 A;  5C5B A;  2EFK A;  2ELB A;  2X3V A;  3QE6 A;  2RAI A;  4NQI A;  2D1L A;  2RAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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