1ZWWA

Crystal structure of endophilin-a1 bar domain
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
220
structure length
199
Chain Sequence
TKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDMEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFGYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Endophilin-A1 BAR Domain.
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords SH3-containing GRB2-like protein 2
total genus 86
structure length 199
sequence length 220
chains with identical sequence B
ec nomenclature ec 2.3.1.-:
pdb deposition date 2005-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 1zwwA00
4DCNC 3HAHA 3SOGA 2V0OA 2RAIA 4DYLA 4H8SA 3QE6A 2C08A 2Z0NA 2Z0OA 1I4LA 3M3WA 4ATMA 3OK8A 4WPCA 2X3VA 3Q0KA 4AKVA 2ELBA 3HAIA 1WDZA 3HAJA 5C5BA 1I49A 2EFLA 2Z0VA 1X04A 2RAKA 4AVMA 2Q12A 1URUA 1X03A 1ZWWA 3G9GA 2X3WA 3ACOA 1I4TA 3SYVA 3CAZA 3DYTA 4BNEA 4FZSA 2YKTA 3LLLA 3PLTA 2X3XA 3ABHA 5C5BB 4NSWA 4WPEA 3I2WA 3QWEA 4NQIA 2RAJA 2Q13A 3Q84A 1Y2OA 3QNIA 4I1QA 2D1LA 1I4DA 2FICA 2D4CA 2EFKA
chains in the Genus database with same CATH superfamily
2V0OA 5KBPA 2QFFA 2Z8YA 4JN4A 3D52A 4FZOA 2ALWA 2EFLA 2ZXQA 4UDYX 1DKXA 1SU7A 3G9GA 3BVXA 4EZVA 3BUIA 3BLBA 5TKYA 1R33A 1OA1A 3I01A 3T49A 3GI7A 5FLEX 2PY6A 3HAIA 2YLLA 1MJGA 2JNKA 2Q13A 2YI9A 2YIVX 2QXLA 3DPQA 4IW0A 1E9VA 3CZSA 2YIBA 4AVMA 3BUDA 3OHXM 5C5BB 3VEAA 4WPEA 2EX3B 3DDFA 1GN9A 4EZQA 4UDXX 2D4CA 4DCNC 1W9MA 3QE6A 1QWNA 2YIAA 3CV5A 2FYVA 3BUQA 4G6QA 4EZRA 2ELBA 5C5BA 3BUPA 4EZSA 2X3WA 3ACOA 3CZNA 3LLLA 1SU6A 3QWEA 4DYLA 3EJRA 1E1DA 4F00A 4JWDA 4AKVA 2MI7A 1PS3A 2WYHA 2OW7A 1OA0A 4EZUA 3I39X 3I2WA 2RAJA 3QNIA 3DPPA 2D1LA 4KIKA 4AZ6A 2X5CA 5E84A 1TQVA 4AZBA 3LMFA 1JQKA 3Q0KA 1WDZA 1TQWA 2RAKA 1X03A 4BNEA 3PLTA 4HYBA 2YL9A 2ND0A 2ND1A 4I1QA 1Y2OA 3F7WA 4H6IA 1I4DA 4R5JA 1HTYA 3DPOA 4FZPA 2EWFA 4EZPA 1ZWWA 4M0MA 3SYVA 4FZSA 2OZNB 4IWPA 4EZTA 4EZZA 1OAOA 4NQIA 3FD9A 3HAHA 3T4AG 2C08A 3A98A 4AZCB 3RV0A 3O3NB 3C7NA 3OK8A 3O3OB 4R5KA 1QX1A 3B52X 4EZXA 2Z0VA 3DDGA 2OBMA 3BVTA 2X3XA 2WINM 4AZCA 3CVRA 4H8SA 3EJSA 3DX0A 1GNTA 4EZNA 3DYTA 3QA8A 4NPHA 3ABHA 4EZYA 2YI8A 1E2UA 2N3KA 3L3OM 2F1AA 1LQ7A 4B9QA 3O3MB 3SOGA 2RAIA 2PMRA 2LM0A 2GA9D 2X3VA 3B51X 4KIKB 4PO2A 2GF4A 2OO2A 1R34A 1SU8A 4JWEA 3CKDA 5FIGA 1O7DC 1UPXA 3KAWA 4H6HA 3ERCC 3EJTA 4AZ7A 1HWWA 3D4ZA 3BVUA 2JNSA 4JWIA 4JNFA 1I49A 4HY9A 2QKWA 1URUA 2YL5A 2F7QA 3D51A 4EZOA 4IM0A 3VKHA 2Z0NA 3DX4A 4ATMA 3ER8C 3BUBA 2F7RA 3B53X 4AZIA 1DKZA 2F18A 3KAVA 3BVVA 2OW6A 4AZHA 3CAZA 2F7PA 1YWMA 2KHOA 3QNJA 4AZGA 4IM2A 2FICA 2LXYA 1I4LA 1HXKA 4F01A 3VEBA 4R5GA 3KDRA 1GNLA 3UITA 1SUFA 1DKYA 1I4TA 4IWQA 2O0I1 4NSWA 1TQTA 2F1BA 3DX3A 2YLAA 4JWCA 3Q84A 4E81A 1QWUA 4JNEA 1R5EA 4R5IA 3ER9B 3T48A 3I04A 1X04A 2WYIA 3D2EA 2Q12A 2YKTA 3OWGA 3ZEDA 3DX2A 2GAFD 4FM3A 4HR1B 3EJUA 2YL8A 1U00A 2Z0OA 3RPMA 4JL9A 4WPCA 3D50A 4EZWA 2RT6A 2YL6A 4HR1A 3D4YA 3L3PA 1TQUA 2F7OA 2NCZA 2EFKA 4D8JA 1ZYLA 3RV1A 4JLCA 2OBLA 3M3WA 4E3CA 4IM3A 3EJPA 3LVTA 1TQSA 3HAJA 3EJQA 4IWOA 3BVWA 3T47A 4AZ5A 1O7DB 3DX1A 3D2FA 3T46A 4R5LA
chains in the Genus database with same CATH topology
4DCNC 3HAHA 3SOGA 2V0OA 2RAIA 4DYLA 4H8SA 3QE6A 2C08A 2Z0NA 2Z0OA 1I4LA 3M3WA 4ATMA 3OK8A 4WPCA 2X3VA 3Q0KA 4AKVA 2ELBA 3HAIA 1WDZA 3HAJA 5C5BA 1I49A 2EFLA 2Z0VA 1X04A 2RAKA 4AVMA 2Q12A 1URUA 1X03A 1ZWWA 3G9GA 2X3WA 3ACOA 1I4TA 3SYVA 3CAZA 3DYTA 4BNEA 4FZSA 2YKTA 3LLLA 3PLTA 2X3XA 3ABHA 5C5BB 4NSWA 4WPEA 3I2WA 3QWEA 4NQIA 2RAJA 2Q13A 3Q84A 1Y2OA 3QNIA 4I1QA 2D1LA 1I4DA 2FICA 2D4CA 2EFKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DCN C;  3HAH A;  3SOG A;  2V0O A;  2RAI A;  4DYL A;  4H8S A;  3QE6 A;  2C08 A;  2Z0N A;  2Z0O A;  1I4L A;  3M3W A;  4ATM A;  3OK8 A;  4WPC A;  2X3V A;  3Q0K A;  4AKV A;  2ELB A;  3HAI A;  1WDZ A;  3HAJ A;  5C5B A;  1I49 A;  2EFL A;  2Z0V A;  1X04 A;  2RAK A;  4AVM A;  2Q12 A;  1URU A;  1X03 A;  1ZWW A;  3G9G A;  2X3W A;  3ACO A;  1I4T A;  3SYV A;  3CAZ A;  3DYT A;  4BNE A;  4FZS A;  2YKT A;  3LLL A;  3PLT A;  2X3X A;  3ABH A;  5C5B B;  4NSW A;  4WPE A;  3I2W A;  3QWE A;  4NQI A;  2RAJ A;  2Q13 A;  3Q84 A;  1Y2O A;  3QNI A;  4I1Q A;  2D1L A;  1I4D A;  2FIC A;  2D4C A;  2EFK A; 
#chains in the Genus database with same CATH topology
 2V0O A;  5KBP A;  2QFF A;  2Z8Y A;  4JN4 A;  3D52 A;  4FZO A;  2ALW A;  2EFL A;  2ZXQ A;  4UDY X;  1DKX A;  1SU7 A;  3G9G A;  3BVX A;  4EZV A;  3BUI A;  3BLB A;  5TKY A;  1R33 A;  1OA1 A;  3I01 A;  3T49 A;  3GI7 A;  5FLE X;  2PY6 A;  3HAI A;  2YLL A;  1MJG A;  2JNK A;  2Q13 A;  2YI9 A;  2YIV X;  2QXL A;  3DPQ A;  4IW0 A;  1E9V A;  3CZS A;  2YIB A;  4AVM A;  3BUD A;  3OHX M;  5C5B B;  3VEA A;  4WPE A;  2EX3 B;  3DDF A;  1GN9 A;  4EZQ A;  4UDX X;  2D4C A;  4DCN C;  1W9M A;  3QE6 A;  1QWN A;  2YIA A;  3CV5 A;  2FYV A;  3BUQ A;  4G6Q A;  4EZR A;  2ELB A;  5C5B A;  3BUP A;  4EZS A;  2X3W A;  3ACO A;  3CZN A;  3LLL A;  1SU6 A;  3QWE A;  4DYL A;  3EJR A;  1E1D A;  4F00 A;  4JWD A;  4AKV A;  2MI7 A;  1PS3 A;  2WYH A;  2OW7 A;  1OA0 A;  4EZU A;  3I39 X;  3I2W A;  2RAJ A;  3QNI A;  3DPP A;  2D1L A;  4KIK A;  4AZ6 A;  2X5C A;  5E84 A;  1TQV A;  4AZB A;  3LMF A;  1JQK A;  3Q0K A;  1WDZ A;  1TQW A;  2RAK A;  1X03 A;  4BNE A;  3PLT A;  4HYB A;  2YL9 A;  2ND0 A;  2ND1 A;  4I1Q A;  1Y2O A;  3F7W A;  4H6I A;  1I4D A;  4R5J A;  1HTY A;  3DPO A;  4FZP A;  2EWF A;  4EZP A;  1ZWW A;  4M0M A;  3SYV A;  4FZS A;  2OZN B;  4IWP A;  4EZT A;  4EZZ A;  1OAO A;  4NQI A;  3FD9 A;  3HAH A;  3T4A G;  2C08 A;  3A98 A;  4AZC B;  3RV0 A;  3O3N B;  3C7N A;  3OK8 A;  3O3O B;  4R5K A;  1QX1 A;  3B52 X;  4EZX A;  2Z0V A;  3DDG A;  2OBM A;  3BVT A;  2X3X A;  2WIN M;  4AZC A;  3CVR A;  4H8S A;  3EJS A;  3DX0 A;  1GNT A;  4EZN A;  3DYT A;  3QA8 A;  4NPH A;  3ABH A;  4EZY A;  2YI8 A;  1E2U A;  2N3K A;  3L3O M;  2F1A A;  1LQ7 A;  4B9Q A;  3O3M B;  3SOG A;  2RAI A;  2PMR A;  2LM0 A;  2GA9 D;  2X3V A;  3B51 X;  4KIK B;  4PO2 A;  2GF4 A;  2OO2 A;  1R34 A;  1SU8 A;  4JWE A;  3CKD A;  5FIG A;  1O7D C;  1UPX A;  3KAW A;  4H6H A;  3ERC C;  3EJT A;  4AZ7 A;  1HWW A;  3D4Z A;  3BVU A;  2JNS A;  4JWI A;  4JNF A;  1I49 A;  4HY9 A;  2QKW A;  1URU A;  2YL5 A;  2F7Q A;  3D51 A;  4EZO A;  4IM0 A;  3VKH A;  2Z0N A;  3DX4 A;  4ATM A;  3ER8 C;  3BUB A;  2F7R A;  3B53 X;  4AZI A;  1DKZ A;  2F18 A;  3KAV A;  3BVV A;  2OW6 A;  4AZH A;  3CAZ A;  2F7P A;  1YWM A;  2KHO A;  3QNJ A;  4AZG A;  4IM2 A;  2FIC A;  2LXY A;  1I4L A;  1HXK A;  4F01 A;  3VEB A;  4R5G A;  3KDR A;  1GNL A;  3UIT A;  1SUF A;  1DKY A;  1I4T A;  4IWQ A;  2O0I 1;  4NSW A;  1TQT A;  2F1B A;  3DX3 A;  2YLA A;  4JWC A;  3Q84 A;  4E81 A;  1QWU A;  4JNE A;  1R5E A;  4R5I A;  3ER9 B;  3T48 A;  3I04 A;  1X04 A;  2WYI A;  3D2E A;  2Q12 A;  2YKT A;  3OWG A;  3ZED A;  3DX2 A;  2GAF D;  4FM3 A;  4HR1 B;  3EJU A;  2YL8 A;  1U00 A;  2Z0O A;  3RPM A;  4JL9 A;  4WPC A;  3D50 A;  4EZW A;  2RT6 A;  2YL6 A;  4HR1 A;  3D4Y A;  3L3P A;  1TQU A;  2F7O A;  2NCZ A;  2EFK A;  4D8J A;  1ZYL A;  3RV1 A;  4JLC A;  2OBL A;  3M3W A;  4E3C A;  4IM3 A;  3EJP A;  3LVT A;  1TQS A;  3HAJ A;  3EJQ A;  4IWO A;  3BVW A;  3T47 A;  4AZ5 A;  1O7D B;  3DX1 A;  3D2F A;  3T46 A;  4R5L A; 
#chains in the Genus database with same CATH homology
 4DCN C;  3HAH A;  3SOG A;  2V0O A;  2RAI A;  4DYL A;  4H8S A;  3QE6 A;  2C08 A;  2Z0N A;  2Z0O A;  1I4L A;  3M3W A;  4ATM A;  3OK8 A;  4WPC A;  2X3V A;  3Q0K A;  4AKV A;  2ELB A;  3HAI A;  1WDZ A;  3HAJ A;  5C5B A;  1I49 A;  2EFL A;  2Z0V A;  1X04 A;  2RAK A;  4AVM A;  2Q12 A;  1URU A;  1X03 A;  1ZWW A;  3G9G A;  2X3W A;  3ACO A;  1I4T A;  3SYV A;  3CAZ A;  3DYT A;  4BNE A;  4FZS A;  2YKT A;  3LLL A;  3PLT A;  2X3X A;  3ABH A;  5C5B B;  4NSW A;  4WPE A;  3I2W A;  3QWE A;  4NQI A;  2RAJ A;  2Q13 A;  3Q84 A;  1Y2O A;  3QNI A;  4I1Q A;  2D1L A;  1I4D A;  2FIC A;  2D4C A;  2EFK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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