1X03A

Crystal structure of endophilin bar domain
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
222
structure length
210
Chain Sequence
GTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMIPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords SH3-containing GRB2-like protein 2
total genus 79
structure length 210
sequence length 222
ec nomenclature ec 2.3.1.-:
pdb deposition date 2005-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 1x03A00
1I49A 3SYVA 4AVMA 2D4CA 2RAJA 2Q13A 2FICA 2YKTA 2RAIA 3QE6A 1WDZA 3HAHA 3HAJA 2Z0OA 3QWEA 2Q12A 1I4TA 2C08A 4I1QA 3CAZA 1I4DA 4H8SA 2Z0VA 3QNIA 3LLLA 4NQIA 4AKVA 2X3XA 3I2WA 3OK8A 3Q0KA 1ZWWA 4BNEA 3G9GA 2X3WA 3PLTA 3ACOA 1X04A 1Y2OA 5C5BB 2EFLA 4WPEA 3DYTA 4DCNC 3SOGA 5C5BA 2D1LA 2ELBA 4ATMA 2RAKA 4FZSA 4DYLA 2V0OA 1X03A 3HAIA 1I4LA 2Z0NA 3M3WA 1URUA 2X3VA 3Q84A 4NSWA 4WPCA 2EFKA 3ABHA
chains in the Genus database with same CATH superfamily
2EWFA 3QE6A 2F7PA 5E84A 2QXLA 2WINM 4EZRA 2OW6A 4AKVA 2YIVX 3A98A 2X3XA 2MI7A 4PO2A 4AZHA 4R5JA 4JL9A 3L3PA 2Q13A 1GNLA 1GNTA 4IWOA 3HAHA 3O3NB 3QWEA 3D2FA 1QX1A 2O0I1 3OK8A 3G9GA 1TQTA 3EJUA 3D52A 4EZQA 5C5BA 4EZYA 3KAWA 2FICA 4HR1A 4EZTA 3HAJA 1E2UA 2PMRA 2YL6A 4I1QA 2YL5A 3DPOA 3ERCC 3VEBA 3DX1A 4AZ6A 2QFFA 2D1LA 3BUPA 1W9MA 3O3OB 2ND1A 4WPCA 2YLAA 2LXYA 1OA0A 3DX4A 3T47A 2Z0VA 4R5GA 3Q0KA 3L3OM 3BVWA 3CV5A 3EJSA 3BUIA 3SYVA 3BUBA 1DKZA 3CVRA 4EZPA 1WDZA 3CZSA 4JWCA 4JWEA 1TQWA 4JWIA 3D4ZA 2N3KA 4EZVA 4H6HA 1SUFA 3D51A 4KIKB 3RV1A 3T46A 4EZNA 1E9VA 1JQKA 4AZCB 1TQSA 1DKYA 2RAKA 1DKXA 2LM0A 2X3VA 4E81A 2GAFD 2YKTA 4F01A 2YI9A 3DDGA 2OBLA 2F7OA 4EZXA 3D4YA 2X5CA 1MJGA 4WPEA 1GN9A 3T4AG 3QNJA 3C7NA 3DX0A 2D4CA 2F18A 1QWNA 4F00A 3EJRA 3DX3A 4NQIA 3BUQA 4BNEA 2ND0A 2X3WA 4B9QA 2PY6A 3UITA 3EJQA 1QWUA 1HTYA 1R33A 2ELBA 4IM3A 4R5IA 3ER9B 2Z0NA 2RT6A 2Z0OA 4UDYX 3DPQA 2GA9D 3CAZA 1I4DA 5FIGA 4AZIA 1ZWWA 3ACOA 2EFLA 3T48A 1I4LA 1SU7A 1URUA 3I01A 4EZZA 2RAJA 4AZGA 2RAIA 1U00A 5TKYA 3BLBA 3DDFA 2JNKA 4EZSA 1SU8A 3CZNA 3DX2A 3KDRA 5C5BB 3RV0A 4AZBA 3SOGA 1X03A 2EFKA 5KBPA 3OHXM 2WYHA 3VKHA 4HR1B 4EZUA 1PS3A 2YI8A 3O3MB 3RPMA 3D50A 1R34A 2F7RA 3OWGA 2OZNB 3LMFA 4G6QA 1TQVA 3T49A 4IWPA 4JNFA 2YIBA 2V0OA 2FYVA 1HXKA 3GI7A 4EZWA 1I49A 3B51X 2Q12A 2JNSA 4H8SA 4M0MA 4D8JA 3KAVA 1HWWA 4NPHA 3DYTA 3B53X 2ALWA 1OA1A 3LVTA 1O7DB 4AVMA 2GF4A 2YL8A 2OBMA 4IM0A 4E3CA 1I4TA 3ZEDA 4HY9A 2C08A 4IM2A 1X04A 1O7DC 4DCNC 3CKDA 3D2EA 3BVVA 3EJTA 1ZYLA 4IWQA 2OW7A 3BVUA 3VEAA 2YIAA 3B52X 3ER8C 3QNIA 3LLLA 3EJPA 4AZ5A 1OAOA 1TQUA 2ZXQA 1LQ7A 4JNEA 3Q84A 2Z8YA 3BVXA 3ABHA 3BVTA 2F1AA 2QKWA 4JWDA 2NCZA 2EX3B 2YLLA 1E1DA 2OO2A 4IW0A 1UPXA 3BUDA 4KIKA 4HYBA 4UDXX 4ATMA 4AZCA 4R5LA 2F1BA 4NSWA 3I04A 3FD9A 4JN4A 3I2WA 2KHOA 1YWMA 1R5EA 1SU6A 1Y2OA 4H6IA 4FZSA 3M3WA 2WYIA 4AZ7A 3HAIA 3DPPA 4EZOA 4FZPA 4FZOA 2F7QA 4R5KA 3I39X 3QA8A 5FLEX 2YL9A 3PLTA 4FM3A 4DYLA 4JLCA 3F7WA
chains in the Genus database with same CATH topology
1I49A 3SYVA 4AVMA 2D4CA 2RAJA 2Q13A 2FICA 2YKTA 2RAIA 3QE6A 1WDZA 3HAHA 3HAJA 2Z0OA 3QWEA 2Q12A 1I4TA 2C08A 4I1QA 3CAZA 1I4DA 4H8SA 2Z0VA 3QNIA 3LLLA 4NQIA 4AKVA 2X3XA 3I2WA 3OK8A 3Q0KA 1ZWWA 4BNEA 3G9GA 2X3WA 3PLTA 3ACOA 1X04A 1Y2OA 5C5BB 2EFLA 4WPEA 3DYTA 4DCNC 3SOGA 5C5BA 2D1LA 2ELBA 4ATMA 2RAKA 4FZSA 4DYLA 2V0OA 1X03A 3HAIA 1I4LA 2Z0NA 3M3WA 1URUA 2X3VA 3Q84A 4NSWA 4WPCA 2EFKA 3ABHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I49 A;  3SYV A;  4AVM A;  2D4C A;  2RAJ A;  2Q13 A;  2FIC A;  2YKT A;  2RAI A;  3QE6 A;  1WDZ A;  3HAH A;  3HAJ A;  2Z0O A;  3QWE A;  2Q12 A;  1I4T A;  2C08 A;  4I1Q A;  3CAZ A;  1I4D A;  4H8S A;  2Z0V A;  3QNI A;  3LLL A;  4NQI A;  4AKV A;  2X3X A;  3I2W A;  3OK8 A;  3Q0K A;  1ZWW A;  4BNE A;  3G9G A;  2X3W A;  3PLT A;  3ACO A;  1X04 A;  1Y2O A;  5C5B B;  2EFL A;  4WPE A;  3DYT A;  4DCN C;  3SOG A;  5C5B A;  2D1L A;  2ELB A;  4ATM A;  2RAK A;  4FZS A;  4DYL A;  2V0O A;  1X03 A;  3HAI A;  1I4L A;  2Z0N A;  3M3W A;  1URU A;  2X3V A;  3Q84 A;  4NSW A;  4WPC A;  2EFK A;  3ABH A; 
#chains in the Genus database with same CATH topology
 2EWF A;  3QE6 A;  2F7P A;  5E84 A;  2QXL A;  2WIN M;  4EZR A;  2OW6 A;  4AKV A;  2YIV X;  3A98 A;  2X3X A;  2MI7 A;  4PO2 A;  4AZH A;  4R5J A;  4JL9 A;  3L3P A;  2Q13 A;  1GNL A;  1GNT A;  4IWO A;  3HAH A;  3O3N B;  3QWE A;  3D2F A;  1QX1 A;  2O0I 1;  3OK8 A;  3G9G A;  1TQT A;  3EJU A;  3D52 A;  4EZQ A;  5C5B A;  4EZY A;  3KAW A;  2FIC A;  4HR1 A;  4EZT A;  3HAJ A;  1E2U A;  2PMR A;  2YL6 A;  4I1Q A;  2YL5 A;  3DPO A;  3ERC C;  3VEB A;  3DX1 A;  4AZ6 A;  2QFF A;  2D1L A;  3BUP A;  1W9M A;  3O3O B;  2ND1 A;  4WPC A;  2YLA A;  2LXY A;  1OA0 A;  3DX4 A;  3T47 A;  2Z0V A;  4R5G A;  3Q0K A;  3L3O M;  3BVW A;  3CV5 A;  3EJS A;  3BUI A;  3SYV A;  3BUB A;  1DKZ A;  3CVR A;  4EZP A;  1WDZ A;  3CZS A;  4JWC A;  4JWE A;  1TQW A;  4JWI A;  3D4Z A;  2N3K A;  4EZV A;  4H6H A;  1SUF A;  3D51 A;  4KIK B;  3RV1 A;  3T46 A;  4EZN A;  1E9V A;  1JQK A;  4AZC B;  1TQS A;  1DKY A;  2RAK A;  1DKX A;  2LM0 A;  2X3V A;  4E81 A;  2GAF D;  2YKT A;  4F01 A;  2YI9 A;  3DDG A;  2OBL A;  2F7O A;  4EZX A;  3D4Y A;  2X5C A;  1MJG A;  4WPE A;  1GN9 A;  3T4A G;  3QNJ A;  3C7N A;  3DX0 A;  2D4C A;  2F18 A;  1QWN A;  4F00 A;  3EJR A;  3DX3 A;  4NQI A;  3BUQ A;  4BNE A;  2ND0 A;  2X3W A;  4B9Q A;  2PY6 A;  3UIT A;  3EJQ A;  1QWU A;  1HTY A;  1R33 A;  2ELB A;  4IM3 A;  4R5I A;  3ER9 B;  2Z0N A;  2RT6 A;  2Z0O A;  4UDY X;  3DPQ A;  2GA9 D;  3CAZ A;  1I4D A;  5FIG A;  4AZI A;  1ZWW A;  3ACO A;  2EFL A;  3T48 A;  1I4L A;  1SU7 A;  1URU A;  3I01 A;  4EZZ A;  2RAJ A;  4AZG A;  2RAI A;  1U00 A;  5TKY A;  3BLB A;  3DDF A;  2JNK A;  4EZS A;  1SU8 A;  3CZN A;  3DX2 A;  3KDR A;  5C5B B;  3RV0 A;  4AZB A;  3SOG A;  1X03 A;  2EFK A;  5KBP A;  3OHX M;  2WYH A;  3VKH A;  4HR1 B;  4EZU A;  1PS3 A;  2YI8 A;  3O3M B;  3RPM A;  3D50 A;  1R34 A;  2F7R A;  3OWG A;  2OZN B;  3LMF A;  4G6Q A;  1TQV A;  3T49 A;  4IWP A;  4JNF A;  2YIB A;  2V0O A;  2FYV A;  1HXK A;  3GI7 A;  4EZW A;  1I49 A;  3B51 X;  2Q12 A;  2JNS A;  4H8S A;  4M0M A;  4D8J A;  3KAV A;  1HWW A;  4NPH A;  3DYT A;  3B53 X;  2ALW A;  1OA1 A;  3LVT A;  1O7D B;  4AVM A;  2GF4 A;  2YL8 A;  2OBM A;  4IM0 A;  4E3C A;  1I4T A;  3ZED A;  4HY9 A;  2C08 A;  4IM2 A;  1X04 A;  1O7D C;  4DCN C;  3CKD A;  3D2E A;  3BVV A;  3EJT A;  1ZYL A;  4IWQ A;  2OW7 A;  3BVU A;  3VEA A;  2YIA A;  3B52 X;  3ER8 C;  3QNI A;  3LLL A;  3EJP A;  4AZ5 A;  1OAO A;  1TQU A;  2ZXQ A;  1LQ7 A;  4JNE A;  3Q84 A;  2Z8Y A;  3BVX A;  3ABH A;  3BVT A;  2F1A A;  2QKW A;  4JWD A;  2NCZ A;  2EX3 B;  2YLL A;  1E1D A;  2OO2 A;  4IW0 A;  1UPX A;  3BUD A;  4KIK A;  4HYB A;  4UDX X;  4ATM A;  4AZC A;  4R5L A;  2F1B A;  4NSW A;  3I04 A;  3FD9 A;  4JN4 A;  3I2W A;  2KHO A;  1YWM A;  1R5E A;  1SU6 A;  1Y2O A;  4H6I A;  4FZS A;  3M3W A;  2WYI A;  4AZ7 A;  3HAI A;  3DPP A;  4EZO A;  4FZP A;  4FZO A;  2F7Q A;  4R5K A;  3I39 X;  3QA8 A;  5FLE X;  2YL9 A;  3PLT A;  4FM3 A;  4DYL A;  4JLC A;  3F7W A; 
#chains in the Genus database with same CATH homology
 1I49 A;  3SYV A;  4AVM A;  2D4C A;  2RAJ A;  2Q13 A;  2FIC A;  2YKT A;  2RAI A;  3QE6 A;  1WDZ A;  3HAH A;  3HAJ A;  2Z0O A;  3QWE A;  2Q12 A;  1I4T A;  2C08 A;  4I1Q A;  3CAZ A;  1I4D A;  4H8S A;  2Z0V A;  3QNI A;  3LLL A;  4NQI A;  4AKV A;  2X3X A;  3I2W A;  3OK8 A;  3Q0K A;  1ZWW A;  4BNE A;  3G9G A;  2X3W A;  3PLT A;  3ACO A;  1X04 A;  1Y2O A;  5C5B B;  2EFL A;  4WPE A;  3DYT A;  4DCN C;  3SOG A;  5C5B A;  2D1L A;  2ELB A;  4ATM A;  2RAK A;  4FZS A;  4DYL A;  2V0O A;  1X03 A;  3HAI A;  1I4L A;  2Z0N A;  3M3W A;  1URU A;  2X3V A;  3Q84 A;  4NSW A;  4WPC A;  2EFK A;  3ABH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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