1ZWWA

Crystal structure of endophilin-a1 bar domain
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
220
structure length
199
Chain Sequence
TKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDMEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFGYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of the Endophilin-A1 BAR Domain.
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords SH3-containing GRB2-like protein 2
total genus 86
structure length 199
sequence length 220
chains with identical sequence B
ec nomenclature ec 2.3.1.-:
pdb deposition date 2005-06-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 1zwwA00
2RAJA 3QNIA 4FZSA 3QWEA 4NQIA 3HAHA 3PLTA 2RAKA 1I4LA 1I4TA 2Z0NA 1WDZA 3DYTA 3M3WA 2FICA 4DYLA 5C5BA 2EFLA 3ACOA 2Z0OA 3I2WA 3LLLA 4AVMA 3HAJA 2YKTA 4WPCA 1Y2OA 2ELBA 3CAZA 3G9GA 3Q0KA 2V0OA 4H8SA 4AKVA 2Z0VA 4ATMA 4WPEA 4DCNC 1X04A 2EFKA 3ABHA 1URUA 3HAIA 4NSWA 1I49A 3QE6A 2C08A 2Q13A 5C5BB 3SYVA 2X3VA 2X3WA 1ZWWA 1X03A 3OK8A 4I1QA 4BNEA 2X3XA 1I4DA 2D4CA 2Q12A 3Q84A 3SOGA 2D1LA 2RAIA
chains in the Genus database with same CATH superfamily
4AZ6A 2NCZA 2WYHA 3PLTA 2Z0NA 4EZTA 2Z0OA 1GNTA 3C7NA 1Y2OA 4UDXX 4EZSA 3EJSA 3VEAA 3T48A 4NSWA 3DX2A 4IW0A 1DKXA 3DX0A 3T47A 4JN4A 3T49A 4AZCB 3D2FA 1QWNA 2JNSA 4JNFA 1GNLA 2F18A 3BUIA 3VKHA 2FYVA 2YIVX 2OW7A 2KHOA 4R5GA 3QNJA 2QFFA 3CVRA 4NPHA 2OO2A 3OK8A 2O0I1 1QWUA 4EZUA 2RAIA 2JNKA 3CZSA 4AKVA 1HXKA 3BUPA 4IM2A 2F7PA 1JQKA 1HWWA 2LXYA 3DX4A 2EFKA 1URUA 2X3VA 3L3OM 3D51A 1E1DA 3EJUA 3Q84A 2D1LA 2ND1A 1O7DB 2F1BA 3DPQA 3F7WA 2WINM 2FICA 2X5CA 2F7OA 1OAOA 3ERCC 1E2UA 4R5IA 3A98A 4AZGA 4AZCA 2N3KA 3KDRA 3BLBA 4KIKB 3EJRA 3L3PA 2Z8YA 4JL9A 3I2WA 2F7RA 4FZOA 4EZOA 1X04A 4JWIA 2Q13A 4E81A 4FZPA 2F1AA 3OHXM 3DDGA 3D4ZA 2RAKA 3D2EA 2YIAA 4EZXA 3LLLA 4WPCA 2V0OA 4IWQA 1QX1A 3BVUA 3O3MB 4AZIA 3SYVA 3DX1A 1DKYA 5TKYA 1TQTA 3CZNA 1W9MA 2WYIA 3CV5A 3QWEA 3DDFA 4R5LA 3T4AG 4DYLA 2YL9A 4IWOA 1MJGA 2ELBA 4H6IA 4D8JA 4KIKA 4B9QA 1UPXA 1YWMA 2C08A 5FLEX 2RT6A 1X03A 4EZYA 1I4DA 2D4CA 2RAJA 4FZSA 2YI8A 3CAZA 2Z0VA 4HR1A 4EZZA 4FM3A 4R5JA 1DKZA 2ND0A 2ALWA 4NQIA 3KAVA 3M3WA 1OA1A 3BUQA 4EZVA 3OWGA 2F7QA 2OBLA 3FD9A 3QA8A 4HY9A 3EJQA 3D52A 5KBPA 4EZPA 3O3NB 1R5EA 3G9GA 4ATMA 4HYBA 3I04A 3BVWA 2YL6A 2YL8A 2GA9D 1TQVA 1ZWWA 3CKDA 3D50A 4I1QA 4HR1B 1HTYA 2Q12A 4WPEA 4H6HA 3LMFA 4JWDA 3ER9B 3DPPA 1I4TA 5C5BA 2GF4A 2QKWA 3ZEDA 4EZNA 2MI7A 1TQUA 3ABHA 3BVXA 1I49A 2OBMA 4E3CA 3B53X 4AZHA 1R34A 4R5KA 3SOGA 3QNIA 2OW6A 2EX3B 4M0MA 3RPMA 4AVMA 2YKTA 4EZRA 3EJTA 4JWEA 3BUDA 1ZYLA 2PMRA 3ER8C 4JLCA 1E9VA 1O7DC 1SU6A 1OA0A 1SU7A 2YI9A 1LQ7A 2YL5A 2EFLA 1PS3A 4F01A 3UITA 3Q0KA 3O3OB 2YIBA 3VEBA 3RV0A 5C5BB 3KAWA 4EZQA 2YLLA 2OZNB 3BUBA 2X3XA 3I01A 2QXLA 3DYTA 1SUFA 4UDYX 4JWCA 3ACOA 1GN9A 4G6QA 4H8SA 1R33A 4JNEA 2PY6A 4IM0A 4IWPA 1SU8A 1TQWA 4BNEA 3LVTA 3D4YA 1U00A 5E84A 3HAHA 3EJPA 1I4LA 4EZWA 3RV1A 5FIGA 4AZ7A 3T46A 3HAIA 3I39X 3B51X 2X3WA 2LM0A 3GI7A 4IM3A 2EWFA 2YLAA 1WDZA 4AZBA 3DX3A 2GAFD 2ZXQA 3HAJA 3B52X 3DPOA 4DCNC 4F00A 3QE6A 4AZ5A 3BVVA 1TQSA 4PO2A 3BVTA
chains in the Genus database with same CATH topology
2RAJA 3QNIA 4FZSA 3QWEA 4NQIA 3HAHA 3PLTA 2RAKA 1I4LA 1I4TA 2Z0NA 1WDZA 3DYTA 3M3WA 2FICA 4DYLA 5C5BA 2EFLA 3ACOA 2Z0OA 3I2WA 3LLLA 4AVMA 3HAJA 2YKTA 4WPCA 1Y2OA 2ELBA 3CAZA 3G9GA 3Q0KA 2V0OA 4H8SA 4AKVA 2Z0VA 4ATMA 4WPEA 4DCNC 1X04A 2EFKA 3ABHA 1URUA 3HAIA 4NSWA 1I49A 3QE6A 2C08A 2Q13A 5C5BB 3SYVA 2X3VA 2X3WA 1ZWWA 1X03A 3OK8A 4I1QA 4BNEA 2X3XA 1I4DA 2D4CA 2Q12A 3Q84A 3SOGA 2D1LA 2RAIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RAJ A;  3QNI A;  4FZS A;  3QWE A;  4NQI A;  3HAH A;  3PLT A;  2RAK A;  1I4L A;  1I4T A;  2Z0N A;  1WDZ A;  3DYT A;  3M3W A;  2FIC A;  4DYL A;  5C5B A;  2EFL A;  3ACO A;  2Z0O A;  3I2W A;  3LLL A;  4AVM A;  3HAJ A;  2YKT A;  4WPC A;  1Y2O A;  2ELB A;  3CAZ A;  3G9G A;  3Q0K A;  2V0O A;  4H8S A;  4AKV A;  2Z0V A;  4ATM A;  4WPE A;  4DCN C;  1X04 A;  2EFK A;  3ABH A;  1URU A;  3HAI A;  4NSW A;  1I49 A;  3QE6 A;  2C08 A;  2Q13 A;  5C5B B;  3SYV A;  2X3V A;  2X3W A;  1ZWW A;  1X03 A;  3OK8 A;  4I1Q A;  4BNE A;  2X3X A;  1I4D A;  2D4C A;  2Q12 A;  3Q84 A;  3SOG A;  2D1L A;  2RAI A; 
#chains in the Genus database with same CATH topology
 4AZ6 A;  2NCZ A;  2WYH A;  3PLT A;  2Z0N A;  4EZT A;  2Z0O A;  1GNT A;  3C7N A;  1Y2O A;  4UDX X;  4EZS A;  3EJS A;  3VEA A;  3T48 A;  4NSW A;  3DX2 A;  4IW0 A;  1DKX A;  3DX0 A;  3T47 A;  4JN4 A;  3T49 A;  4AZC B;  3D2F A;  1QWN A;  2JNS A;  4JNF A;  1GNL A;  2F18 A;  3BUI A;  3VKH A;  2FYV A;  2YIV X;  2OW7 A;  2KHO A;  4R5G A;  3QNJ A;  2QFF A;  3CVR A;  4NPH A;  2OO2 A;  3OK8 A;  2O0I 1;  1QWU A;  4EZU A;  2RAI A;  2JNK A;  3CZS A;  4AKV A;  1HXK A;  3BUP A;  4IM2 A;  2F7P A;  1JQK A;  1HWW A;  2LXY A;  3DX4 A;  2EFK A;  1URU A;  2X3V A;  3L3O M;  3D51 A;  1E1D A;  3EJU A;  3Q84 A;  2D1L A;  2ND1 A;  1O7D B;  2F1B A;  3DPQ A;  3F7W A;  2WIN M;  2FIC A;  2X5C A;  2F7O A;  1OAO A;  3ERC C;  1E2U A;  4R5I A;  3A98 A;  4AZG A;  4AZC A;  2N3K A;  3KDR A;  3BLB A;  4KIK B;  3EJR A;  3L3P A;  2Z8Y A;  4JL9 A;  3I2W A;  2F7R A;  4FZO A;  4EZO A;  1X04 A;  4JWI A;  2Q13 A;  4E81 A;  4FZP A;  2F1A A;  3OHX M;  3DDG A;  3D4Z A;  2RAK A;  3D2E A;  2YIA A;  4EZX A;  3LLL A;  4WPC A;  2V0O A;  4IWQ A;  1QX1 A;  3BVU A;  3O3M B;  4AZI A;  3SYV A;  3DX1 A;  1DKY A;  5TKY A;  1TQT A;  3CZN A;  1W9M A;  2WYI A;  3CV5 A;  3QWE A;  3DDF A;  4R5L A;  3T4A G;  4DYL A;  2YL9 A;  4IWO A;  1MJG A;  2ELB A;  4H6I A;  4D8J A;  4KIK A;  4B9Q A;  1UPX A;  1YWM A;  2C08 A;  5FLE X;  2RT6 A;  1X03 A;  4EZY A;  1I4D A;  2D4C A;  2RAJ A;  4FZS A;  2YI8 A;  3CAZ A;  2Z0V A;  4HR1 A;  4EZZ A;  4FM3 A;  4R5J A;  1DKZ A;  2ND0 A;  2ALW A;  4NQI A;  3KAV A;  3M3W A;  1OA1 A;  3BUQ A;  4EZV A;  3OWG A;  2F7Q A;  2OBL A;  3FD9 A;  3QA8 A;  4HY9 A;  3EJQ A;  3D52 A;  5KBP A;  4EZP A;  3O3N B;  1R5E A;  3G9G A;  4ATM A;  4HYB A;  3I04 A;  3BVW A;  2YL6 A;  2YL8 A;  2GA9 D;  1TQV A;  1ZWW A;  3CKD A;  3D50 A;  4I1Q A;  4HR1 B;  1HTY A;  2Q12 A;  4WPE A;  4H6H A;  3LMF A;  4JWD A;  3ER9 B;  3DPP A;  1I4T A;  5C5B A;  2GF4 A;  2QKW A;  3ZED A;  4EZN A;  2MI7 A;  1TQU A;  3ABH A;  3BVX A;  1I49 A;  2OBM A;  4E3C A;  3B53 X;  4AZH A;  1R34 A;  4R5K A;  3SOG A;  3QNI A;  2OW6 A;  2EX3 B;  4M0M A;  3RPM A;  4AVM A;  2YKT A;  4EZR A;  3EJT A;  4JWE A;  3BUD A;  1ZYL A;  2PMR A;  3ER8 C;  4JLC A;  1E9V A;  1O7D C;  1SU6 A;  1OA0 A;  1SU7 A;  2YI9 A;  1LQ7 A;  2YL5 A;  2EFL A;  1PS3 A;  4F01 A;  3UIT A;  3Q0K A;  3O3O B;  2YIB A;  3VEB A;  3RV0 A;  5C5B B;  3KAW A;  4EZQ A;  2YLL A;  2OZN B;  3BUB A;  2X3X A;  3I01 A;  2QXL A;  3DYT A;  1SUF A;  4UDY X;  4JWC A;  3ACO A;  1GN9 A;  4G6Q A;  4H8S A;  1R33 A;  4JNE A;  2PY6 A;  4IM0 A;  4IWP A;  1SU8 A;  1TQW A;  4BNE A;  3LVT A;  3D4Y A;  1U00 A;  5E84 A;  3HAH A;  3EJP A;  1I4L A;  4EZW A;  3RV1 A;  5FIG A;  4AZ7 A;  3T46 A;  3HAI A;  3I39 X;  3B51 X;  2X3W A;  2LM0 A;  3GI7 A;  4IM3 A;  2EWF A;  2YLA A;  1WDZ A;  4AZB A;  3DX3 A;  2GAF D;  2ZXQ A;  3HAJ A;  3B52 X;  3DPO A;  4DCN C;  4F00 A;  3QE6 A;  4AZ5 A;  3BVV A;  1TQS A;  4PO2 A;  3BVT A; 
#chains in the Genus database with same CATH homology
 2RAJ A;  3QNI A;  4FZS A;  3QWE A;  4NQI A;  3HAH A;  3PLT A;  2RAK A;  1I4L A;  1I4T A;  2Z0N A;  1WDZ A;  3DYT A;  3M3W A;  2FIC A;  4DYL A;  5C5B A;  2EFL A;  3ACO A;  2Z0O A;  3I2W A;  3LLL A;  4AVM A;  3HAJ A;  2YKT A;  4WPC A;  1Y2O A;  2ELB A;  3CAZ A;  3G9G A;  3Q0K A;  2V0O A;  4H8S A;  4AKV A;  2Z0V A;  4ATM A;  4WPE A;  4DCN C;  1X04 A;  2EFK A;  3ABH A;  1URU A;  3HAI A;  4NSW A;  1I49 A;  3QE6 A;  2C08 A;  2Q13 A;  5C5B B;  3SYV A;  2X3V A;  2X3W A;  1ZWW A;  1X03 A;  3OK8 A;  4I1Q A;  4BNE A;  2X3X A;  1I4D A;  2D4C A;  2Q12 A;  3Q84 A;  3SOG A;  2D1L A;  2RAI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...