2DXBB

Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
pubmed doi rcsb
molecule tags Hydrolase
source organism Thiobacillus thioparus
molecule keywords Thiocyanate hydrolase subunit alpha
total genus 46
structure length 152
sequence length 152
chains with identical sequence E, H, K, N, Q, T, W
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2006-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2dxbB00
2ZPBB 1UGQB 1UGSB 2ZPFB 3X20B 1UGPB 2DD4B 2D0QB 2CZ0B 3X24B 3A8GB 4FM4B 2ZPIB 3QYGB 4OB3B 3HHTB 4OB1B 4ZGEB 2ZZDB 3WVEB 3QXEB 3QYHB 4OB0B 2CZ1B 2DXBB 2QDYB 1V29B 3VYGB 2ZCFB 3QZ9B 2DPPB 2AHJB 2CYZB 3X25B 3A8HB 2CZ7B 3X28B 3QZ5B 2ZPHB 4ZGJB 3A8LB 1UGRB 3A8MB 4OB2B 2CZ6B 2DXCB 2ZPGB 3VYHB 2DD5B 2ZPEB 1AHJB 4ZGDB 3WVDB 3A8OB 3X26B 1IREB
chains in the Genus database with same CATH superfamily
2LW4A 1AD6A 4F7LB 5IF1B 4I3ZB 2D0QB 5CYIB 2I53A 3QYGB 4MIMA 4MFDA 2BKZB 1FINB 5HBHB 3BG3A 5EJCA 2AHJB 2JGZB 3A8HB 3BG9A 1VYWB 2CZ6B 4CXAB 4HL4A 4ZGDB 1UNLD 2V22B 1OL2B 2WEVB 3MY1B 3TNWB 4BCJB 4QSHA 4BCMB 4F6SB 2BPMB 2CZ0B 2I40B 4OB0B 2CZ1B 3TW6A 3BLRB 4LOCA 1D3UB 4AKHA 3GTMS 3A8MB 4BBSM 1E7PA 1G3NC 3KHIA 3WVDB 1JSUB 1TFBA 2ZPBB 2IN3A 4BCQB 4F6UB 2UZDB 4EORB 5BNJB 1V29B 2UZEB 4CFWB 4F7JB 3QZ5B 1XO2A 1UGRB 1OIYB 1AHJB 5FGKB 2WMBB 1H28B 4EOIB 4BCHB 3X24B 2UZLB 1E9HB 1OGUB 4YOSA 2IW6B 1JKWA 3BHTB 3VKHA 4ZGJB 2QFZA 2DXCB 4KRDB 2W9FA 3POMA 2PHGA 1GUXA 5EFQB 3X20B 4KRCB 4ROCA 5IDPB 5IDNB 4JX5A 4EOMB 2BS3A 2CCHB 1H25B 1N4MA 4CFUB 2CCIB 3TNHB 1FKMA 3M03A 3H4CA 3QHWB 3HBLA 4HNUA 1C9BA 5HNBB 4BY7X 2DD5B 4EC9B 2KMGA 2WIHB 2WPAB 3X26B 2PK9B 1W98B 5L2WB 4HNTA 4YOZA 4OR5B 1H1QB 4Y72B 1GUXB 2PJQA 5LQFB 4BCNB 1QMZB 4EOQB 2ZPEB 1H24B 2B9RA 4EONB 4JX4A 3MIAB 4TTHA 4ELJA 4FM4B 4HLQA 4F7SB 2C5NB 1JSTB 2DXBB 2KR6A 3VYGB 4FX3B 4AKGA 3HB9A 4EC8B 2W99A 3EOCB 4BXXX 4F7NB 1ENWA 4AI6A 3TN8B 3DOGB 2UUEB 1OIUB 3BHUB 5CEIB 3BLQB 1O9KA 2WMAB 4OB3B 4ROEA 1H26B 3WVEB 3QHRB 5DQWA 2QGSA 3TW7A 4EOKB 1GH6B 2QDJA 2BS2A 4EOLB 3EJ1B 2CZ7B 2W96A 4BY1X 4CFXB 3A8OB 4BCFB 4YOOA 4RODA 4CFVB 3A8GB 2F2CA 3HHTB 4BCPB 4BCGB 3HZJA 4BCMD 1ZP2A 1BU2A 2G9XB 3X28B 2IW9B 1O9KB 3K7AM 3VYHB 1VINA 4F70B 2IW8B 4G6LB 1H1PB 5IHYA 3MY5B 4AKIA 2UZBB 2ZPIB 4BCIB 4IMYB 2C4GB 2W2HA 2C5VB 3EIDB 4MFEA 3DJBA 2C5OB 3NDQA 3A8LB 1KXUA 4BCKB 1QLBA 1H1SB 4NSTB 4M6VA 4ZGEB 1AISB 4CFMB 3TNIB 1F5QB 1OL1B 1UNGD 2CYZB 2QF7A 4F6WB 1P5EB 4Z6YA 3PO3S 3LQ5B 3BG5A 2CJMB 3O0GD 2R7GA 2G77A 3BHVB 1UGSB 2ZZDB 5ICPB 1H27B 4EOPB 2WFYB 5HBJB 2WXVB 4EOOB 3B57A 3X25B 3DTOA 2WJ9A 3F5XB 4II5B 1OKVB 2EUFA 5HVYB 3QYEA 5LMKB 1UGQB 2ZPFB 3VKGA 2DD4B 4YC3B 4EOJB 4CFUD 5HQ0B 2ZCFB 5I5ZB 4ELLA 2W9ZA 1JOWA 3MI9B 1URCB 1OKWB 1FVVB 5ACBA 2WHBB 2BS4A 4BCOB 1H1RB 3DDQB 4OGRB 2PMIB 2C6TB 4OB1B 3HO8A 4HNVA 3QXEB 3QYHB 1GY3B 2PK2A 2WIPB 2X1NB 4BCND 3QYBA 3QWLA 2DPPB 2DMEA 4OB2B 2ZPGB 3BLHB 2C5XB 4NC6A 4CFNB 1UGPB 3DL1A 1TD6A 4UN0A 3RGFB 1PKDB 5DQVA 3DDPB 1H4LD 2QDYB 2QQ8A 1UNHD 3QZ9B 4BBRM 1OI9B 3G33B 4CRLB 4JX6A 1VOLA 2ZPHB 4EOSB 5HBEB 2IVXA 4BCQD 1IREB
chains in the Genus database with same CATH topology
1UGSB 2D0QB 3X24B 4OB3B 3QYGB 4MIMA 2ZZDB 3WVEB 3TW7A 4MFDA 2QDJA 3BG3A 5EJCA 2AHJB 2BS2A 3X25B 3VKHA 2WJ9A 2CZ7B 3A8HB 3BG9A 4ZGJB 2CZ6B 2DXCB 2QFZA 4HL4A 4ZGDB 3A8OB 3QYEA 1UGQB 2ZPFB 3X20B 3VKGA 2DD4B 3A8GB 3HHTB 4JX5A 2BS3A 4QSHA 3HZJA 2ZCFB 1FKMA 3H4CA 3HBLA 4HNUA 3X28B 3VYHB 2DD5B 2KMGA 3X26B 4AKIA 2BS4A 4HNTA 2CZ0B 2ZPIB 4OB1B 4HNVA 3HO8A 3QXEB 3QYHB 4OB0B 2CZ1B 3TW6A 4LOCA 3QYBA 4MFEA 3QWLA 2DPPB 4AKHA 3A8LB 3A8MB 4OB2B 2ZPGB 4BBSM 2ZPEB 1QLBA 1E7PA 3KHIA 3WVDB 4JX4A 4NC6A 2ZPBB 4ELJA 1UGPB 3DL1A 4FM4B 4M6VA 4HLQA 4ZGEB 2DXBB 2QDYB 2QQ8A 2KR6A 1V29B 3VYGB 3QZ9B 4BBRM 2CYZB 2QF7A 4AKGA 4JX6A 3HB9A 3QZ5B 2ZPHB 1UGRB 4Z6YA 3BG5A 4AI6A 1AHJB 2G77A 1IREB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZPB B;  1UGQ B;  1UGS B;  2ZPF B;  3X20 B;  1UGP B;  2DD4 B;  2D0Q B;  2CZ0 B;  3X24 B;  3A8G B;  4FM4 B;  2ZPI B;  3QYG B;  4OB3 B;  3HHT B;  4OB1 B;  4ZGE B;  2ZZD B;  3WVE B;  3QXE B;  3QYH B;  4OB0 B;  2CZ1 B;  2DXB B;  2QDY B;  1V29 B;  3VYG B;  2ZCF B;  3QZ9 B;  2DPP B;  2AHJ B;  2CYZ B;  3X25 B;  3A8H B;  2CZ7 B;  3X28 B;  3QZ5 B;  2ZPH B;  4ZGJ B;  3A8L B;  1UGR B;  3A8M B;  4OB2 B;  2CZ6 B;  2DXC B;  2ZPG B;  3VYH B;  2DD5 B;  2ZPE B;  1AHJ B;  4ZGD B;  3WVD B;  3A8O B;  3X26 B;  1IRE B; 
#chains in the Genus database with same CATH topology
 2LW4 A;  1AD6 A;  4F7L B;  5IF1 B;  4I3Z B;  2D0Q B;  5CYI B;  2I53 A;  3QYG B;  4MIM A;  4MFD A;  2BKZ B;  1FIN B;  5HBH B;  3BG3 A;  5EJC A;  2AHJ B;  2JGZ B;  3A8H B;  3BG9 A;  1VYW B;  2CZ6 B;  4CXA B;  4HL4 A;  4ZGD B;  1UNL D;  2V22 B;  1OL2 B;  2WEV B;  3MY1 B;  3TNW B;  4BCJ B;  4QSH A;  4BCM B;  4F6S B;  2BPM B;  2CZ0 B;  2I40 B;  4OB0 B;  2CZ1 B;  3TW6 A;  3BLR B;  4LOC A;  1D3U B;  4AKH A;  3GTM S;  3A8M B;  4BBS M;  1E7P A;  1G3N C;  3KHI A;  3WVD B;  1JSU B;  1TFB A;  2ZPB B;  2IN3 A;  4BCQ B;  4F6U B;  2UZD B;  4EOR B;  5BNJ B;  1V29 B;  2UZE B;  4CFW B;  4F7J B;  3QZ5 B;  1XO2 A;  1UGR B;  1OIY B;  1AHJ B;  5FGK B;  2WMB B;  1H28 B;  4EOI B;  4BCH B;  3X24 B;  2UZL B;  1E9H B;  1OGU B;  4YOS A;  2IW6 B;  1JKW A;  3BHT B;  3VKH A;  4ZGJ B;  2QFZ A;  2DXC B;  4KRD B;  2W9F A;  3POM A;  2PHG A;  1GUX A;  5EFQ B;  3X20 B;  4KRC B;  4ROC A;  5IDP B;  5IDN B;  4JX5 A;  4EOM B;  2BS3 A;  2CCH B;  1H25 B;  1N4M A;  4CFU B;  2CCI B;  3TNH B;  1FKM A;  3M03 A;  3H4C A;  3QHW B;  3HBL A;  4HNU A;  1C9B A;  5HNB B;  4BY7 X;  2DD5 B;  4EC9 B;  2KMG A;  2WIH B;  2WPA B;  3X26 B;  2PK9 B;  1W98 B;  5L2W B;  4HNT A;  4YOZ A;  4OR5 B;  1H1Q B;  4Y72 B;  1GUX B;  2PJQ A;  5LQF B;  4BCN B;  1QMZ B;  4EOQ B;  2ZPE B;  1H24 B;  2B9R A;  4EON B;  4JX4 A;  3MIA B;  4TTH A;  4ELJ A;  4FM4 B;  4HLQ A;  4F7S B;  2C5N B;  1JST B;  2DXB B;  2KR6 A;  3VYG B;  4FX3 B;  4AKG A;  3HB9 A;  4EC8 B;  2W99 A;  3EOC B;  4BXX X;  4F7N B;  1ENW A;  4AI6 A;  3TN8 B;  3DOG B;  2UUE B;  1OIU B;  3BHU B;  5CEI B;  3BLQ B;  1O9K A;  2WMA B;  4OB3 B;  4ROE A;  1H26 B;  3WVE B;  3QHR B;  5DQW A;  2QGS A;  3TW7 A;  4EOK B;  1GH6 B;  2QDJ A;  2BS2 A;  4EOL B;  3EJ1 B;  2CZ7 B;  2W96 A;  4BY1 X;  4CFX B;  3A8O B;  4BCF B;  4YOO A;  4ROD A;  4CFV B;  3A8G B;  2F2C A;  3HHT B;  4BCP B;  4BCG B;  3HZJ A;  4BCM D;  1ZP2 A;  1BU2 A;  2G9X B;  3X28 B;  2IW9 B;  1O9K B;  3K7A M;  3VYH B;  1VIN A;  4F70 B;  2IW8 B;  4G6L B;  1H1P B;  5IHY A;  3MY5 B;  4AKI A;  2UZB B;  2ZPI B;  4BCI B;  4IMY B;  2C4G B;  2W2H A;  2C5V B;  3EID B;  4MFE A;  3DJB A;  2C5O B;  3NDQ A;  3A8L B;  1KXU A;  4BCK B;  1QLB A;  1H1S B;  4NST B;  4M6V A;  4ZGE B;  1AIS B;  4CFM B;  3TNI B;  1F5Q B;  1OL1 B;  1UNG D;  2CYZ B;  2QF7 A;  4F6W B;  1P5E B;  4Z6Y A;  3PO3 S;  3LQ5 B;  3BG5 A;  2CJM B;  3O0G D;  2R7G A;  2G77 A;  3BHV B;  1UGS B;  2ZZD B;  5ICP B;  1H27 B;  4EOP B;  2WFY B;  5HBJ B;  2WXV B;  4EOO B;  3B57 A;  3X25 B;  3DTO A;  2WJ9 A;  3F5X B;  4II5 B;  1OKV B;  2EUF A;  5HVY B;  3QYE A;  5LMK B;  1UGQ B;  2ZPF B;  3VKG A;  2DD4 B;  4YC3 B;  4EOJ B;  4CFU D;  5HQ0 B;  2ZCF B;  5I5Z B;  4ELL A;  2W9Z A;  1JOW A;  3MI9 B;  1URC B;  1OKW B;  1FVV B;  5ACB A;  2WHB B;  2BS4 A;  4BCO B;  1H1R B;  3DDQ B;  4OGR B;  2PMI B;  2C6T B;  4OB1 B;  3HO8 A;  4HNV A;  3QXE B;  3QYH B;  1GY3 B;  2PK2 A;  2WIP B;  2X1N B;  4BCN D;  3QYB A;  3QWL A;  2DPP B;  2DME A;  4OB2 B;  2ZPG B;  3BLH B;  2C5X B;  4NC6 A;  4CFN B;  1UGP B;  3DL1 A;  1TD6 A;  4UN0 A;  3RGF B;  1PKD B;  5DQV A;  3DDP B;  1H4L D;  2QDY B;  2QQ8 A;  1UNH D;  3QZ9 B;  4BBR M;  1OI9 B;  3G33 B;  4CRL B;  4JX6 A;  1VOL A;  2ZPH B;  4EOS B;  5HBE B;  2IVX A;  4BCQ D;  1IRE B; 
#chains in the Genus database with same CATH homology
 1UGS B;  2D0Q B;  3X24 B;  4OB3 B;  3QYG B;  4MIM A;  2ZZD B;  3WVE B;  3TW7 A;  4MFD A;  2QDJ A;  3BG3 A;  5EJC A;  2AHJ B;  2BS2 A;  3X25 B;  3VKH A;  2WJ9 A;  2CZ7 B;  3A8H B;  3BG9 A;  4ZGJ B;  2CZ6 B;  2DXC B;  2QFZ A;  4HL4 A;  4ZGD B;  3A8O B;  3QYE A;  1UGQ B;  2ZPF B;  3X20 B;  3VKG A;  2DD4 B;  3A8G B;  3HHT B;  4JX5 A;  2BS3 A;  4QSH A;  3HZJ A;  2ZCF B;  1FKM A;  3H4C A;  3HBL A;  4HNU A;  3X28 B;  3VYH B;  2DD5 B;  2KMG A;  3X26 B;  4AKI A;  2BS4 A;  4HNT A;  2CZ0 B;  2ZPI B;  4OB1 B;  4HNV A;  3HO8 A;  3QXE B;  3QYH B;  4OB0 B;  2CZ1 B;  3TW6 A;  4LOC A;  3QYB A;  4MFE A;  3QWL A;  2DPP B;  4AKH A;  3A8L B;  3A8M B;  4OB2 B;  2ZPG B;  4BBS M;  2ZPE B;  1QLB A;  1E7P A;  3KHI A;  3WVD B;  4JX4 A;  4NC6 A;  2ZPB B;  4ELJ A;  1UGP B;  3DL1 A;  4FM4 B;  4M6V A;  4HLQ A;  4ZGE B;  2DXB B;  2QDY B;  2QQ8 A;  2KR6 A;  1V29 B;  3VYG B;  3QZ9 B;  4BBR M;  2CYZ B;  2QF7 A;  4AKG A;  4JX6 A;  3HB9 A;  3QZ5 B;  2ZPH B;  1UGR B;  4Z6Y A;  3BG5 A;  4AI6 A;  1AHJ B;  2G77 A;  1IRE B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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