2DXBB

Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Thiocyanate hydrolase subunit alpha
publication title Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
pubmed doi rcsb
source organism Thiobacillus thioparus
total genus 46
structure length 152
sequence length 152
chains with identical sequence E, H, K, N, Q, T, W
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2006-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2dxbB00
3A8HB 3HHTB 2D0QB 2DD4B 2AHJB 3QZ5B 1IREB 2ZPGB 4ZGDB 4ZGEB 2CZ7B 3X26B 3WVDB 4OB2B 3A8MB 4OB3B 2DD5B 2ZCFB 2ZPIB 2DXBB 2ZPBB 3QXEB 4FM4B 3A8GB 3QYGB 2DPPB 1UGPB 3A8LB 1V29B 2ZPFB 3VYHB 4ZGJB 4OB1B 2CYZB 3X24B 3QYHB 3X25B 2ZZDB 2CZ0B 1UGQB 2CZ6B 1UGSB 3A8OB 4OB0B 3X28B 2ZPHB 3QZ9B 3VYGB 3X20B 2QDYB 3WVEB 1AHJB 1UGRB 2CZ1B 2DXCB 2ZPEB
chains in the Genus database with same CATH superfamily
2W99A 3HZJA 2I53A 4F7SB 4KRDB 2IW6B 4JX4A 4BCQD 2V22B 1V29B 4BCJB 2QFZA 2WFYB 1H4LD 2KMGA 3HO8A 4RODA 2B9RA 2CZ6B 3HBLA 4HNUA 3LQ5B 4AKIA 1OIYB 2WEVB 4BCHB 5HBJB 2BS2A 1JKWA 3A8MB 2DD5B 2UZEB 5EJCA 1E9HB 1H25B 3BLHB 2QDYB 5ACBA 2CZ1B 3RGFB 4BBRM 2G9XB 2W9ZA 4CFMB 4M6VA 1F5QB 4EOPB 4ELJA 1JSUB 1OGUB 2ZPBB 2ZPIB 4EOOB 3DOGB 2LW4A 3DL1A 4BY7X 4QSHA 4CFNB 1IREB 4F7LB 2IVXA 4ELLA 3QYGB 3QHWB 2DPPB 3DJBA 4BCFB 4EORB 3M03A 3KHIA 3MY5B 2WMAB 4EOKB 1BU2A 3VKGA 1AISB 3QHRB 3A8HB 4MFDA 2UZDB 2DD4B 4AKHA 3QZ5B 4F7NB 3G33B 1N4MA 4OB3B 5CEIB 3EIDB 1QMZB 2EUFA 2WIPB 2WMBB 3POMA 4BBSM 4UN0A 4EONB 4BCMD 4BXXX 1H26B 4YC3B 1FINB 5IDPB 4CFUD 5HNBB 2C5VB 2BS3A 2BKZB 3X24B 4NSTB 5HVYB 4JX6A 3QYBA 3QWLA 3VYGB 1FVVB 1E7PA 3DDQB 4HNVA 4BCND 1VOLA 3BG5A 1UNLD 3A8GB 1ZP2A 1H1PB 1UGPB 3F5XB 3MI9B 2PMIB 2C5XB 2WJ9A 2ZZDB 2CZ0B 5FGKB 1GY3B 4ROCA 2X1NB 3O0GD 3BG3A 1OI9B 5EFQB 3PO3S 3TW7A 1ENWA 4AI6A 1OL1B 2W2HA 4EOLB 4I3ZB 2QQ8A 2PJQA 3B57A 2WPAB 4CFWB 4EOQB 4CXAB 2BS4A 1URCB 5HBHB 3BLQB 3VKHA 1UNGD 4CFXB 2PK2A 5I5ZB 5CYIB 1D3UB 2WIHB 4HLQA 4CRLB 2IN3A 3MIAB 4OB2B 3DDPB 2F2CA 4F6WB 4F6UB 2CYZB 1H24B 2BPMB 3X25B 1UGSB 3A8OB 4AKGA 4F70B 1OL2B 1UNHD 1W98B 3HB9A 4EC8B 4OR5B 4ZGDB 1GUXA 2DMEA 4G6LB 1C9BA 2DXBB 2QF7A 3EOCB 4MFEA 3VYHB 1TFBA 1UGQB 3K7AM 4YOZA 4KRCB 4MIMA 2ZPEB 5IF1B 1O9KA 1GH6B 4IMYB 4Y72B 2ZPGB 3X26B 4FM4B 3TNHB 1G3NC 5LQFB 2IW9B 4F7JB 5IDNB 4CFVB 1P5EB 4II5B 3X28B 3X20B 3BHTB 4FX3B 2CCHB 1H1RB 1H1QB 2C5OB 1VYWB 2C4GB 2CZ7B 3EJ1B 4NC6A 2IW8B 4OB1B 1FKMA 2C6TB 2UZBB 2ZPHB 3GTMS 1H28B 2C5NB 2KR6A 2D0QB 2UUEB 5IHYA 5DQVA 3WVDB 4LOCA 4JX5A 1OKWB 3MY1B 2UZLB 4YOOA 1AD6A 1H27B 1TD6A 2W96A 3WVEB 4BCPB 3BG9A 4F6SB 2G77A 2I40B 3HHTB 1XO2A 4EOJB 1OKVB 2AHJB 2JGZB 4BCGB 4ROEA 4BCOB 3H4CA 3TNWB 2QDJA 2ZCFB 5L2WB 4HNTA 4BCMB 4YOSA 2WXVB 1H1SB 2PK9B 1KXUA 2R7GA 4BCIB 4CFUB 1GUXB 4TTHA 2W9FA 1AHJB 4Z6YA 4EC9B 2DXCB 3DTOA 1VINA 1PKDB 5DQWA 4BCQB 4ZGEB 1JOWA 5ICPB 3QYEA 5BNJB 1QLBA 2QGSA 4HL4A 3TW6A 4BCKB 1O9KB 5HBEB 3TNIB 4OB0B 3BHVB 5HQ0B 4EOMB 3BLRB 4BCNB 3BHUB 4EOSB 3NDQA 2PHGA 3QXEB 4EOIB 3A8LB 2ZPFB 3TN8B 4ZGJB 4OGRB 5LMKB 3QYHB 1JSTB 2CCIB 3QZ9B 1OIUB 4BY1X 1UGRB 2WHBB 2CJMB
chains in the Genus database with same CATH topology
3A8HB 4MFDA 3HZJA 2KR6A 2D0QB 2DD4B 4HLQA 4AKHA 3QZ5B 3WVDB 4OB2B 4LOCA 4OB3B 4JX5A 4JX4A 1V29B 2CYZB 2QFZA 3X25B 2KMGA 3HO8A 2CZ6B 1UGSB 3A8OB 4AKGA 4BBSM 3HBLA 3WVEB 4HNUA 4AKIA 3BG9A 2G77A 3HHTB 3HB9A 2BS2A 2AHJB 4ZGDB 2BS3A 3A8MB 3H4CA 2DD5B 2QDJA 2ZCFB 2DXBB 2QF7A 4MFEA 3VYHB 4HNTA 3X24B 4JX6A 3QYBA 3QWLA 5EJCA 1UGQB 3VYGB 2QDYB 1AHJB 2CZ1B 4Z6YA 4MIMA 4BBRM 2DXCB 2ZPEB 1E7PA 4HNVA 4M6VA 2ZPGB 3BG5A 4ZGEB 3X26B 3QYEA 4ELJA 4FM4B 2ZPBB 2ZPIB 3A8GB 1QLBA 1UGPB 4HL4A 3TW6A 2WJ9A 2ZZDB 2CZ0B 3X28B 4OB0B 3X20B 3BG3A 3TW7A 3DL1A 4AI6A 4QSHA 1IREB 2CZ7B 2QQ8A 3QXEB 3QYGB 2DPPB 3A8LB 2ZPFB 4NC6A 4ZGJB 4OB1B 2BS4A 3QYHB 3KHIA 1FKMA 3VKHA 2ZPHB 3QZ9B 3VKGA 1UGRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A8H B;  3HHT B;  2D0Q B;  2DD4 B;  2AHJ B;  3QZ5 B;  1IRE B;  2ZPG B;  4ZGD B;  4ZGE B;  2CZ7 B;  3X26 B;  3WVD B;  4OB2 B;  3A8M B;  4OB3 B;  2DD5 B;  2ZCF B;  2ZPI B;  2DXB B;  2ZPB B;  3QXE B;  4FM4 B;  3A8G B;  3QYG B;  2DPP B;  1UGP B;  3A8L B;  1V29 B;  2ZPF B;  3VYH B;  4ZGJ B;  4OB1 B;  2CYZ B;  3X24 B;  3QYH B;  3X25 B;  2ZZD B;  2CZ0 B;  1UGQ B;  2CZ6 B;  1UGS B;  3A8O B;  4OB0 B;  3X28 B;  2ZPH B;  3QZ9 B;  3VYG B;  3X20 B;  2QDY B;  3WVE B;  1AHJ B;  1UGR B;  2CZ1 B;  2DXC B;  2ZPE B; 
#chains in the Genus database with same CATH topology
 2W99 A;  3HZJ A;  2I53 A;  4F7S B;  4KRD B;  2IW6 B;  4JX4 A;  4BCQ D;  2V22 B;  1V29 B;  4BCJ B;  2QFZ A;  2WFY B;  1H4L D;  2KMG A;  3HO8 A;  4ROD A;  2B9R A;  2CZ6 B;  3HBL A;  4HNU A;  3LQ5 B;  4AKI A;  1OIY B;  2WEV B;  4BCH B;  5HBJ B;  2BS2 A;  1JKW A;  3A8M B;  2DD5 B;  2UZE B;  5EJC A;  1E9H B;  1H25 B;  3BLH B;  2QDY B;  5ACB A;  2CZ1 B;  3RGF B;  4BBR M;  2G9X B;  2W9Z A;  4CFM B;  4M6V A;  1F5Q B;  4EOP B;  4ELJ A;  1JSU B;  1OGU B;  2ZPB B;  2ZPI B;  4EOO B;  3DOG B;  2LW4 A;  3DL1 A;  4BY7 X;  4QSH A;  4CFN B;  1IRE B;  4F7L B;  2IVX A;  4ELL A;  3QYG B;  3QHW B;  2DPP B;  3DJB A;  4BCF B;  4EOR B;  3M03 A;  3KHI A;  3MY5 B;  2WMA B;  4EOK B;  1BU2 A;  3VKG A;  1AIS B;  3QHR B;  3A8H B;  4MFD A;  2UZD B;  2DD4 B;  4AKH A;  3QZ5 B;  4F7N B;  3G33 B;  1N4M A;  4OB3 B;  5CEI B;  3EID B;  1QMZ B;  2EUF A;  2WIP B;  2WMB B;  3POM A;  4BBS M;  4UN0 A;  4EON B;  4BCM D;  4BXX X;  1H26 B;  4YC3 B;  1FIN B;  5IDP B;  4CFU D;  5HNB B;  2C5V B;  2BS3 A;  2BKZ B;  3X24 B;  4NST B;  5HVY B;  4JX6 A;  3QYB A;  3QWL A;  3VYG B;  1FVV B;  1E7P A;  3DDQ B;  4HNV A;  4BCN D;  1VOL A;  3BG5 A;  1UNL D;  3A8G B;  1ZP2 A;  1H1P B;  1UGP B;  3F5X B;  3MI9 B;  2PMI B;  2C5X B;  2WJ9 A;  2ZZD B;  2CZ0 B;  5FGK B;  1GY3 B;  4ROC A;  2X1N B;  3O0G D;  3BG3 A;  1OI9 B;  5EFQ B;  3PO3 S;  3TW7 A;  1ENW A;  4AI6 A;  1OL1 B;  2W2H A;  4EOL B;  4I3Z B;  2QQ8 A;  2PJQ A;  3B57 A;  2WPA B;  4CFW B;  4EOQ B;  4CXA B;  2BS4 A;  1URC B;  5HBH B;  3BLQ B;  3VKH A;  1UNG D;  4CFX B;  2PK2 A;  5I5Z B;  5CYI B;  1D3U B;  2WIH B;  4HLQ A;  4CRL B;  2IN3 A;  3MIA B;  4OB2 B;  3DDP B;  2F2C A;  4F6W B;  4F6U B;  2CYZ B;  1H24 B;  2BPM B;  3X25 B;  1UGS B;  3A8O B;  4AKG A;  4F70 B;  1OL2 B;  1UNH D;  1W98 B;  3HB9 A;  4EC8 B;  4OR5 B;  4ZGD B;  1GUX A;  2DME A;  4G6L B;  1C9B A;  2DXB B;  2QF7 A;  3EOC B;  4MFE A;  3VYH B;  1TFB A;  1UGQ B;  3K7A M;  4YOZ A;  4KRC B;  4MIM A;  2ZPE B;  5IF1 B;  1O9K A;  1GH6 B;  4IMY B;  4Y72 B;  2ZPG B;  3X26 B;  4FM4 B;  3TNH B;  1G3N C;  5LQF B;  2IW9 B;  4F7J B;  5IDN B;  4CFV B;  1P5E B;  4II5 B;  3X28 B;  3X20 B;  3BHT B;  4FX3 B;  2CCH B;  1H1R B;  1H1Q B;  2C5O B;  1VYW B;  2C4G B;  2CZ7 B;  3EJ1 B;  4NC6 A;  2IW8 B;  4OB1 B;  1FKM A;  2C6T B;  2UZB B;  2ZPH B;  3GTM S;  1H28 B;  2C5N B;  2KR6 A;  2D0Q B;  2UUE B;  5IHY A;  5DQV A;  3WVD B;  4LOC A;  4JX5 A;  1OKW B;  3MY1 B;  2UZL B;  4YOO A;  1AD6 A;  1H27 B;  1TD6 A;  2W96 A;  3WVE B;  4BCP B;  3BG9 A;  4F6S B;  2G77 A;  2I40 B;  3HHT B;  1XO2 A;  4EOJ B;  1OKV B;  2AHJ B;  2JGZ B;  4BCG B;  4ROE A;  4BCO B;  3H4C A;  3TNW B;  2QDJ A;  2ZCF B;  5L2W B;  4HNT A;  4BCM B;  4YOS A;  2WXV B;  1H1S B;  2PK9 B;  1KXU A;  2R7G A;  4BCI B;  4CFU B;  1GUX B;  4TTH A;  2W9F A;  1AHJ B;  4Z6Y A;  4EC9 B;  2DXC B;  3DTO A;  1VIN A;  1PKD B;  5DQW A;  4BCQ B;  4ZGE B;  1JOW A;  5ICP B;  3QYE A;  5BNJ B;  1QLB A;  2QGS A;  4HL4 A;  3TW6 A;  4BCK B;  1O9K B;  5HBE B;  3TNI B;  4OB0 B;  3BHV B;  5HQ0 B;  4EOM B;  3BLR B;  4BCN B;  3BHU B;  4EOS B;  3NDQ A;  2PHG A;  3QXE B;  4EOI B;  3A8L B;  2ZPF B;  3TN8 B;  4ZGJ B;  4OGR B;  5LMK B;  3QYH B;  1JST B;  2CCI B;  3QZ9 B;  1OIU B;  4BY1 X;  1UGR B;  2WHB B;  2CJM B; 
#chains in the Genus database with same CATH homology
 3A8H B;  4MFD A;  3HZJ A;  2KR6 A;  2D0Q B;  2DD4 B;  4HLQ A;  4AKH A;  3QZ5 B;  3WVD B;  4OB2 B;  4LOC A;  4OB3 B;  4JX5 A;  4JX4 A;  1V29 B;  2CYZ B;  2QFZ A;  3X25 B;  2KMG A;  3HO8 A;  2CZ6 B;  1UGS B;  3A8O B;  4AKG A;  4BBS M;  3HBL A;  3WVE B;  4HNU A;  4AKI A;  3BG9 A;  2G77 A;  3HHT B;  3HB9 A;  2BS2 A;  2AHJ B;  4ZGD B;  2BS3 A;  3A8M B;  3H4C A;  2DD5 B;  2QDJ A;  2ZCF B;  2DXB B;  2QF7 A;  4MFE A;  3VYH B;  4HNT A;  3X24 B;  4JX6 A;  3QYB A;  3QWL A;  5EJC A;  1UGQ B;  3VYG B;  2QDY B;  1AHJ B;  2CZ1 B;  4Z6Y A;  4MIM A;  4BBR M;  2DXC B;  2ZPE B;  1E7P A;  4HNV A;  4M6V A;  2ZPG B;  3BG5 A;  4ZGE B;  3X26 B;  3QYE A;  4ELJ A;  4FM4 B;  2ZPB B;  2ZPI B;  3A8G B;  1QLB A;  1UGP B;  4HL4 A;  3TW6 A;  2WJ9 A;  2ZZD B;  2CZ0 B;  3X28 B;  4OB0 B;  3X20 B;  3BG3 A;  3TW7 A;  3DL1 A;  4AI6 A;  4QSH A;  1IRE B;  2CZ7 B;  2QQ8 A;  3QXE B;  3QYG B;  2DPP B;  3A8L B;  2ZPF B;  4NC6 A;  4ZGJ B;  4OB1 B;  2BS4 A;  3QYH B;  3KHI A;  1FKM A;  3VKH A;  2ZPH B;  3QZ9 B;  3VKG A;  1UGR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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