2DXBB

Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Thiocyanate hydrolase subunit alpha
publication title Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
pubmed doi rcsb
source organism Thiobacillus thioparus
molecule tags Hydrolase
total genus 46
structure length 152
sequence length 152
chains with identical sequence E, H, K, N, Q, T, W
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2006-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2dxbB00
3WVDB 2DPPB 4ZGJB 1UGQB 2ZCFB 2ZPEB 2CZ7B 2CZ0B 2DD5B 3A8MB 2DXCB 2DXBB 3VYGB 2DD4B 4ZGDB 2CZ6B 2CZ1B 4FM4B 4OB1B 3QXEB 3X28B 1IREB 2ZPIB 3QYGB 2ZPBB 2ZZDB 3X20B 4OB2B 3A8HB 2ZPHB 2AHJB 2ZPGB 1AHJB 3WVEB 3A8OB 4OB3B 2QDYB 2ZPFB 4OB0B 3HHTB 1UGRB 3QZ9B 3VYHB 3X24B 3X26B 3X25B 1UGPB 3QZ5B 4ZGEB 2D0QB 2CYZB 3A8GB 1UGSB 1V29B 3QYHB 3A8LB
chains in the Genus database with same CATH superfamily
1FVVB 1H24B 4EOMB 2IVXA 2CZ6B 3QXEB 4I3ZB 5I5ZB 1UNGD 2ZPBB 1E9HB 1OIUB 1UNLD 5ICPB 3WVEB 4BY7X 3QWLA 3LQ5B 3TNIB 1V29B 1H1PB 4ZGJB 1H28B 3X28B 1GUXA 3QYGB 3TNWB 2QDJA 2X1NB 2PMIB 3F5XB 1FKMA 2WEVB 4BCMB 2D0QB 1UGSB 3QYEA 2ZPEB 4FX3B 2DD5B 4ZGDB 1QMZB 4QSHA 2BS2A 2BS4A 5HBEB 2EUFA 5L2WB 4BY1X 1OL1B 1BU2A 2CYZB 2PHGA 2WIPB 2W99A 1UGQB 2C5VB 4ELLA 1JSUB 5HBHB 2CZ1B 5HVYB 4II5B 4EOIB 3HB9A 2PK2A 2CCHB 4CXAB 4OB0B 3QHRB 2V22B 3DDQB 2IW8B 4F6SB 5BNJB 2F2CA 4YOOA 1H25B 1OI9B 2CZ7B 4EONB 3GTMS 1TFBA 3MIAB 3BHUB 3X24B 4F7JB 2I53A 4HNUA 3A8GB 2W9FA 2W2HA 1UNHD 3QHWB 3K7AM 1VINA 2I40B 4AKHA 4EOPB 1XO2A 2C5NB 3POMA 4EOLB 4OGRB 1F5QB 4Y72B 5HNBB 4TTHA 2CCIB 2IW9B 2QDYB 2ZPFB 1N4MA 5IDPB 3EJ1B 1H4LD 2QF7A 3BLQB 3G33B 2DPPB 3BLRB 4JX6A 3HBLA 2UZDB 4OB3B 2G77A 1OGUB 1ENWA 2UUEB 4YOSA 2C5XB 3QYHB 2QGSA 3BG3A 4KRCB 5HQ0B 4EORB 4CFWB 2CZ0B 3VYGB 2DD4B 4BCHB 5IHYA 1IREB 2BPMB 1H1QB 2ZPGB 3DJBA 3PO3S 1VYWB 1H27B 4BCGB 1H1SB 1QLBA 2C6TB 3EOCB 5HBJB 4F70B 4G6LB 2WJ9A 3DDPB 4CFXB 4ROEA 4YOZA 2WXVB 4EOJB 3A8HB 1OKVB 3QYBA 2KR6A 1OL2B 3VKGA 2JGZB 3QZ9B 1FINB 4BCOB 2PJQA 3MI9B 3BLHB 4F6WB 1P5EB 1W98B 4JX4A 1E7PA 1OKWB 4UN0A 5IDNB 3TNHB 4OB2B 1JOWA 4BCFB 2ZPHB 1GH6B 4F7SB 1KXUA 4BCJB 4HL4A 3X25B 3NDQA 4ZGEB 5DQWA 4ELJA 5LQFB 2UZEB 1AISB 3WVDB 1AD6A 2DXBB 4OR5B 1VOLA 2WIHB 4FM4B 4OB1B 3BHTB 4M6VA 3M03A 3TW6A 4LOCA 2AHJB 2WHBB 4RODA 1UGRB 1TD6A 3BHVB 2WMBB 3KHIA 4BCND 3EIDB 5LMKB 5EJCA 1URCB 1H26B 4BCQD 3A8MB 1JSTB 4F7NB 2R7GA 4ROCA 3DOGB 5EFQB 4BBSM 3VKHA 5CEIB 5ACBA 3X20B 3O0GD 4EOKB 2C4GB 3A8OB 2C5OB 3HO8A 2KMGA 3MY1B 3B57A 4AI6A 4BBRM 4CFUD 4EOSB 5CYIB 3A8LB 2QQ8A 2ZCFB 4IMYB 2B9RA 1H1RB 4EC9B 2ZPIB 1JKWA 2W96A 1O9KB 4HNTA 3VYHB 4EC8B 5DQVA 2G9XB 3RGFB 1PKDB 4MIMA 2WFYB 2PK9B 3TN8B 2IW6B 3DL1A 4AKGA 1G3NC 4F6UB 4EOQB 2UZLB 3HHTB 4F7LB 1UGPB 4HNVA 1OIYB 3QZ5B 4BCNB 2LW4A 4NC6A 3DTOA 4JX5A 4BCQB 2IN3A 3TW7A 2QFZA 4BCKB 4CFMB 2BKZB 2WPAB 5FGKB 4BCPB 4CFVB 3HZJA 4BCIB 1ZP2A 2UZBB 2ZZDB 3BG9A 1GUXB 2CJMB 1C9BA 2WMAB 4BXXX 2DMEA 4AKIA 4BCMD 2BS3A 4CFUB 4MFDA 4CRLB 3H4CA 1D3UB 2DXCB 4CFNB 3BG5A 1O9KA 4HLQA 5IF1B 4KRDB 1AHJB 4NSTB 4MFEA 4Z6YA 3X26B 2W9ZA 4EOOB 1GY3B 4YC3B 3MY5B
chains in the Genus database with same CATH topology
2QQ8A 2ZCFB 2WJ9A 2CZ7B 2CZ6B 3QXEB 2ZPIB 2ZPBB 3A8HB 3QYBA 2KR6A 3WVEB 3VKGA 4HNTA 3QZ9B 3VYHB 3X24B 3QWLA 4HNUA 3A8GB 1V29B 4ZGJB 4MIMA 4JX4A 3X28B 1E7PA 4AKHA 3QYGB 3DL1A 2QDJA 4OB2B 2ZPHB 4AKGA 2QDYB 4HL4A 2ZPFB 3HHTB 1FKMA 3X25B 1UGPB 4HNVA 3QZ5B 4ZGEB 2D0QB 4NC6A 1UGSB 4ELJA 3QYEA 4JX5A 3WVDB 2QF7A 2DPPB 3TW7A 2QFZA 2ZPEB 2DD5B 4JX6A 2DXBB 3HBLA 4ZGDB 4FM4B 4OB1B 4QSHA 2BS2A 2BS4A 3HZJA 4M6VA 2ZZDB 3BG9A 4LOCA 3TW6A 2AHJB 4OB3B 2G77A 1UGRB 4AKIA 3KHIA 2BS3A 4MFDA 2CYZB 5EJCA 3H4CA 3QYHB 3BG3A 1UGQB 3A8MB 2CZ0B 2DXCB 3VYGB 2DD4B 2CZ1B 4BBSM 3VKHA 3BG5A 1IREB 4HLQA 3HB9A 3X20B 2ZPGB 1AHJB 3A8OB 4OB0B 3HO8A 2KMGA 4MFEA 4Z6YA 3X26B 4AI6A 4BBRM 1QLBA 3A8LB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WVD B;  2DPP B;  4ZGJ B;  1UGQ B;  2ZCF B;  2ZPE B;  2CZ7 B;  2CZ0 B;  2DD5 B;  3A8M B;  2DXC B;  2DXB B;  3VYG B;  2DD4 B;  4ZGD B;  2CZ6 B;  2CZ1 B;  4FM4 B;  4OB1 B;  3QXE B;  3X28 B;  1IRE B;  2ZPI B;  3QYG B;  2ZPB B;  2ZZD B;  3X20 B;  4OB2 B;  3A8H B;  2ZPH B;  2AHJ B;  2ZPG B;  1AHJ B;  3WVE B;  3A8O B;  4OB3 B;  2QDY B;  2ZPF B;  4OB0 B;  3HHT B;  1UGR B;  3QZ9 B;  3VYH B;  3X24 B;  3X26 B;  3X25 B;  1UGP B;  3QZ5 B;  4ZGE B;  2D0Q B;  2CYZ B;  3A8G B;  1UGS B;  1V29 B;  3QYH B;  3A8L B; 
#chains in the Genus database with same CATH topology
 1FVV B;  1H24 B;  4EOM B;  2IVX A;  2CZ6 B;  3QXE B;  4I3Z B;  5I5Z B;  1UNG D;  2ZPB B;  1E9H B;  1OIU B;  1UNL D;  5ICP B;  3WVE B;  4BY7 X;  3QWL A;  3LQ5 B;  3TNI B;  1V29 B;  1H1P B;  4ZGJ B;  1H28 B;  3X28 B;  1GUX A;  3QYG B;  3TNW B;  2QDJ A;  2X1N B;  2PMI B;  3F5X B;  1FKM A;  2WEV B;  4BCM B;  2D0Q B;  1UGS B;  3QYE A;  2ZPE B;  4FX3 B;  2DD5 B;  4ZGD B;  1QMZ B;  4QSH A;  2BS2 A;  2BS4 A;  5HBE B;  2EUF A;  5L2W B;  4BY1 X;  1OL1 B;  1BU2 A;  2CYZ B;  2PHG A;  2WIP B;  2W99 A;  1UGQ B;  2C5V B;  4ELL A;  1JSU B;  5HBH B;  2CZ1 B;  5HVY B;  4II5 B;  4EOI B;  3HB9 A;  2PK2 A;  2CCH B;  4CXA B;  4OB0 B;  3QHR B;  2V22 B;  3DDQ B;  2IW8 B;  4F6S B;  5BNJ B;  2F2C A;  4YOO A;  1H25 B;  1OI9 B;  2CZ7 B;  4EON B;  3GTM S;  1TFB A;  3MIA B;  3BHU B;  3X24 B;  4F7J B;  2I53 A;  4HNU A;  3A8G B;  2W9F A;  2W2H A;  1UNH D;  3QHW B;  3K7A M;  1VIN A;  2I40 B;  4AKH A;  4EOP B;  1XO2 A;  2C5N B;  3POM A;  4EOL B;  4OGR B;  1F5Q B;  4Y72 B;  5HNB B;  4TTH A;  2CCI B;  2IW9 B;  2QDY B;  2ZPF B;  1N4M A;  5IDP B;  3EJ1 B;  1H4L D;  2QF7 A;  3BLQ B;  3G33 B;  2DPP B;  3BLR B;  4JX6 A;  3HBL A;  2UZD B;  4OB3 B;  2G77 A;  1OGU B;  1ENW A;  2UUE B;  4YOS A;  2C5X B;  3QYH B;  2QGS A;  3BG3 A;  4KRC B;  5HQ0 B;  4EOR B;  4CFW B;  2CZ0 B;  3VYG B;  2DD4 B;  4BCH B;  5IHY A;  1IRE B;  2BPM B;  1H1Q B;  2ZPG B;  3DJB A;  3PO3 S;  1VYW B;  1H27 B;  4BCG B;  1H1S B;  1QLB A;  2C6T B;  3EOC B;  5HBJ B;  4F70 B;  4G6L B;  2WJ9 A;  3DDP B;  4CFX B;  4ROE A;  4YOZ A;  2WXV B;  4EOJ B;  3A8H B;  1OKV B;  3QYB A;  2KR6 A;  1OL2 B;  3VKG A;  2JGZ B;  3QZ9 B;  1FIN B;  4BCO B;  2PJQ A;  3MI9 B;  3BLH B;  4F6W B;  1P5E B;  1W98 B;  4JX4 A;  1E7P A;  1OKW B;  4UN0 A;  5IDN B;  3TNH B;  4OB2 B;  1JOW A;  4BCF B;  2ZPH B;  1GH6 B;  4F7S B;  1KXU A;  4BCJ B;  4HL4 A;  3X25 B;  3NDQ A;  4ZGE B;  5DQW A;  4ELJ A;  5LQF B;  2UZE B;  1AIS B;  3WVD B;  1AD6 A;  2DXB B;  4OR5 B;  1VOL A;  2WIH B;  4FM4 B;  4OB1 B;  3BHT B;  4M6V A;  3M03 A;  3TW6 A;  4LOC A;  2AHJ B;  2WHB B;  4ROD A;  1UGR B;  1TD6 A;  3BHV B;  2WMB B;  3KHI A;  4BCN D;  3EID B;  5LMK B;  5EJC A;  1URC B;  1H26 B;  4BCQ D;  3A8M B;  1JST B;  4F7N B;  2R7G A;  4ROC A;  3DOG B;  5EFQ B;  4BBS M;  3VKH A;  5CEI B;  5ACB A;  3X20 B;  3O0G D;  4EOK B;  2C4G B;  3A8O B;  2C5O B;  3HO8 A;  2KMG A;  3MY1 B;  3B57 A;  4AI6 A;  4BBR M;  4CFU D;  4EOS B;  5CYI B;  3A8L B;  2QQ8 A;  2ZCF B;  4IMY B;  2B9R A;  1H1R B;  4EC9 B;  2ZPI B;  1JKW A;  2W96 A;  1O9K B;  4HNT A;  3VYH B;  4EC8 B;  5DQV A;  2G9X B;  3RGF B;  1PKD B;  4MIM A;  2WFY B;  2PK9 B;  3TN8 B;  2IW6 B;  3DL1 A;  4AKG A;  1G3N C;  4F6U B;  4EOQ B;  2UZL B;  3HHT B;  4F7L B;  1UGP B;  4HNV A;  1OIY B;  3QZ5 B;  4BCN B;  2LW4 A;  4NC6 A;  3DTO A;  4JX5 A;  4BCQ B;  2IN3 A;  3TW7 A;  2QFZ A;  4BCK B;  4CFM B;  2BKZ B;  2WPA B;  5FGK B;  4BCP B;  4CFV B;  3HZJ A;  4BCI B;  1ZP2 A;  2UZB B;  2ZZD B;  3BG9 A;  1GUX B;  2CJM B;  1C9B A;  2WMA B;  4BXX X;  2DME A;  4AKI A;  4BCM D;  2BS3 A;  4CFU B;  4MFD A;  4CRL B;  3H4C A;  1D3U B;  2DXC B;  4CFN B;  3BG5 A;  1O9K A;  4HLQ A;  5IF1 B;  4KRD B;  1AHJ B;  4NST B;  4MFE A;  4Z6Y A;  3X26 B;  2W9Z A;  4EOO B;  1GY3 B;  4YC3 B;  3MY5 B; 
#chains in the Genus database with same CATH homology
 2QQ8 A;  2ZCF B;  2WJ9 A;  2CZ7 B;  2CZ6 B;  3QXE B;  2ZPI B;  2ZPB B;  3A8H B;  3QYB A;  2KR6 A;  3WVE B;  3VKG A;  4HNT A;  3QZ9 B;  3VYH B;  3X24 B;  3QWL A;  4HNU A;  3A8G B;  1V29 B;  4ZGJ B;  4MIM A;  4JX4 A;  3X28 B;  1E7P A;  4AKH A;  3QYG B;  3DL1 A;  2QDJ A;  4OB2 B;  2ZPH B;  4AKG A;  2QDY B;  4HL4 A;  2ZPF B;  3HHT B;  1FKM A;  3X25 B;  1UGP B;  4HNV A;  3QZ5 B;  4ZGE B;  2D0Q B;  4NC6 A;  1UGS B;  4ELJ A;  3QYE A;  4JX5 A;  3WVD B;  2QF7 A;  2DPP B;  3TW7 A;  2QFZ A;  2ZPE B;  2DD5 B;  4JX6 A;  2DXB B;  3HBL A;  4ZGD B;  4FM4 B;  4OB1 B;  4QSH A;  2BS2 A;  2BS4 A;  3HZJ A;  4M6V A;  2ZZD B;  3BG9 A;  4LOC A;  3TW6 A;  2AHJ B;  4OB3 B;  2G77 A;  1UGR B;  4AKI A;  3KHI A;  2BS3 A;  4MFD A;  2CYZ B;  5EJC A;  3H4C A;  3QYH B;  3BG3 A;  1UGQ B;  3A8M B;  2CZ0 B;  2DXC B;  3VYG B;  2DD4 B;  2CZ1 B;  4BBS M;  3VKH A;  3BG5 A;  1IRE B;  4HLQ A;  3HB9 A;  3X20 B;  2ZPG B;  1AHJ B;  3A8O B;  4OB0 B;  3HO8 A;  2KMG A;  4MFE A;  4Z6Y A;  3X26 B;  4AI6 A;  4BBR M;  1QLB A;  3A8L B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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