2DXCB

Recombinant thiocyanate hydrolase, fully-matured form
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Thiocyanate hydrolase subunit alpha
publication title Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
pubmed doi rcsb
source organism Thiobacillus thioparus
total genus 47
structure length 152
sequence length 152
chains with identical sequence E, H, K
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2006-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2dxcB00
3VYGB 1UGPB 2CYZB 1UGRB 2DXCB 2CZ7B 2ZPIB 2CZ1B 2ZPGB 3QXEB 4OB1B 2ZPHB 1UGSB 2ZZDB 3WVDB 4OB3B 3QYGB 3WVEB 3A8HB 4FM4B 2QDYB 1AHJB 2D0QB 3QZ5B 2ZCFB 2DD5B 3QYHB 4ZGDB 2DPPB 4OB0B 1UGQB 4OB2B 3X26B 2AHJB 2CZ6B 3A8GB 2ZPBB 4ZGJB 2DD4B 3QZ9B 4ZGEB 2ZPFB 3A8OB 3X24B 3X20B 3VYHB 1IREB 3X28B 2DXBB 1V29B 2CZ0B 2ZPEB 3HHTB 3A8LB 3A8MB 3X25B
chains in the Genus database with same CATH superfamily
1URCB 2QF7A 3K7AM 2BS2A 1PKDB 4FX3B 1N4MA 2WFYB 4JX5A 4F7NB 4EOMB 4CFUD 1UNHD 2ZPFB 4ELJA 4BCOB 2CYZB 3QYBA 2CZ7B 5HNBB 3BLHB 2ZPHB 2ZZDB 1OKVB 3A8HB 4EOJB 3BLQB 1H25B 4BCHB 1O9KB 2C5OB 4OB0B 5EJCA 4HNTA 3MY5B 1UNLD 2V22B 1UGPB 2WJ9A 5FGKB 2ZPIB 4BCQD 3WVDB 4CFVB 4G6LB 4BCMD 4EOSB 2IN3A 4Z6YA 4NSTB 4ROCA 3A8GB 2W99A 4BY7X 5IDPB 1H24B 4EOIB 2I53A 3MY1B 4AKIA 2I40B 4EOPB 3POMA 5LMKB 2UZEB 1AD6A 2CZ1B 5CEIB 1GUXA 4CRLB 2QGSA 3VKHA 2C5VB 4CFWB 4BCIB 3G33B 4YOZA 2WMAB 2C6TB 2BS3A 3A8OB 5ICPB 3VYHB 1IREB 2DXBB 1V29B 3EOCB 2DXCB 5L2WB 2QQ8A 2BS4A 5LQFB 3BG5A 4BCFB 4BCND 2ZPBB 3EIDB 4YC3B 1OL2B 2C5NB 4OR5B 3HHTB 5HQ0B 2IVXA 4BCJB 1XO2A 2PJQA 4HL4A 3DTOA 4KRCB 2QDYB 2EUFA 2WPAB 1QMZB 3TNHB 4BCKB 2CCHB 2PMIB 5CYIB 4AKGA 4TTHA 1H1RB 3BHTB 2CZ0B 1P5EB 2LW4A 1H4LD 3MI9B 2ZPGB 2DMEA 3BLRB 1UGSB 1H1PB 2WEVB 4OB3B 4CXAB 3TNIB 1ENWA 2PHGA 2G77A 4F6UB 4MIMA 1JOWA 4IMYB 4BCGB 2UZLB 3BHVB 2KR6A 3WVEB 3HBLA 4F7JB 4BXXX 2CCIB 3X26B 3DL1A 4ROEA 2W9ZA 4MFEA 3A8LB 2BKZB 4BCQB 3TW6A 1H28B 5HBEB 3VYGB 2PK2A 4EONB 2UZDB 1BU2A 4BCMB 1W98B 2ZCFB 3F5XB 1JSUB 4YOOA 4UN0A 3TW7A 1QLBA 1FKMA 2DD4B 1FINB 3QWLA 2WHBB 5BNJB 1G3NC 1TFBA 1OI9B 4ELLA 3NDQA 1GY3B 1H26B 1E9HB 1JKWA 4OB2B 4EOKB 2R7GA 5HBJB 4ZGEB 1H1SB 3QHRB 1O9KA 5HVYB 1OIYB 5HBHB 3BHUB 4EOLB 3KHIA 3BG3A 1UGRB 2QDJA 4HNVA 4MFDA 4FM4B 3DOGB 1AHJB 2IW9B 1GH6B 4BBRM 4F6WB 2UZBB 4JX4A 3LQ5B 3QHWB 2C5XB 2B9RA 5ACBA 1H1QB 3B57A 4F6SB 1GUXB 2JGZB 3A8MB 3TNWB 4AKHA 1OKWB 4RODA 3O0GD 2F2CA 1FVVB 1ZP2A 3QZ5B 2WIHB 3QYHB 3TN8B 4CFUB 2C4GB 2WXVB 4ZGJB 4OGRB 2G9XB 3H4CA 3HZJA 4EOQB 2PK9B 4CFNB 3DDQB 4HLQA 1OIUB 2W9FA 3VKGA 3M03A 4F7LB 5DQVA 3QXEB 4OB1B 3QYGB 4EOOB 2D0QB 2DD5B 2DPPB 4EC9B 2W2HA 2AHJB 2CZ6B 3MIAB 3RGFB 4BCPB 4EC8B 4CFMB 3PO3S 1E7PA 2BPMB 2ZPEB 4YOSA 3HB9A 2UUEB 1D3UB 4LOCA 3DDPB 4M6VA 4JX6A 2WMBB 3DJBA 1UNGD 1OL1B 1AISB 4Y72B 3GTMS 2KMGA 4EORB 2W96A 1VYWB 3X20B 3X25B 1F5QB 4F7SB 1VOLA 4II5B 4HNUA 3BG9A 1KXUA 3HO8A 4I3ZB 4ZGDB 5IDNB 4BBSM 4F70B 5DQWA 5IF1B 5I5ZB 3QZ9B 5EFQB 1OGUB 3X28B 4QSHA 2X1NB 2CJMB 2QFZA 1H27B 1VINA 5IHYA 4BY1X 4BCNB 4AI6A 3QYEA 1UGQB 1JSTB 2IW8B 4KRDB 4CFXB 1TD6A 3X24B 2IW6B 2WIPB 3EJ1B 4NC6A 1C9BA
chains in the Genus database with same CATH topology
3VKGA 3VYGB 2QF7A 2DXCB 3QXEB 4OB1B 3QYGB 2BS2A 2QQ8A 2BS4A 2D0QB 2ZCFB 2DD5B 3BG5A 2DPPB 3TW7A 1QLBA 4JX5A 2AHJB 2CZ6B 1FKMA 2ZPBB 2DD4B 2ZPFB 1E7PA 2ZPEB 4ELJA 3HHTB 3QWLA 3HB9A 2CYZB 3QYBA 2CZ7B 4HL4A 2ZPHB 2ZZDB 4LOCA 3A8HB 2QDYB 4M6VA 4JX6A 4OB0B 4OB2B 5EJCA 4HNTA 2KMGA 4ZGEB 4AKGA 3X20B 2CZ0B 3X25B 1UGPB 2WJ9A 3KHIA 3BG3A 1UGRB 2ZPGB 2ZPIB 1UGSB 3WVDB 4OB3B 2QDJA 4HNVA 4MFDA 4FM4B 4HNUA 3BG9A 3HO8A 1AHJB 4BBRM 4ZGDB 4Z6YA 4BBSM 3A8GB 4JX4A 2G77A 3QZ9B 4MIMA 3X28B 4AKIA 4QSHA 2KR6A 3A8MB 4AKHA 2CZ1B 2QFZA 3WVEB 3HBLA 3QZ5B 3VKHA 3QYHB 4AI6A 3QYEA 1UGQB 3X26B 4ZGJB 3DL1A 3H4CA 2BS3A 3A8OB 3X24B 3HZJA 3VYHB 1IREB 4NC6A 4MFEA 2DXBB 1V29B 3A8LB 3TW6A 4HLQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VYG B;  1UGP B;  2CYZ B;  1UGR B;  2DXC B;  2CZ7 B;  2ZPI B;  2CZ1 B;  2ZPG B;  3QXE B;  4OB1 B;  2ZPH B;  1UGS B;  2ZZD B;  3WVD B;  4OB3 B;  3QYG B;  3WVE B;  3A8H B;  4FM4 B;  2QDY B;  1AHJ B;  2D0Q B;  3QZ5 B;  2ZCF B;  2DD5 B;  3QYH B;  4ZGD B;  2DPP B;  4OB0 B;  1UGQ B;  4OB2 B;  3X26 B;  2AHJ B;  2CZ6 B;  3A8G B;  2ZPB B;  4ZGJ B;  2DD4 B;  3QZ9 B;  4ZGE B;  2ZPF B;  3A8O B;  3X24 B;  3X20 B;  3VYH B;  1IRE B;  3X28 B;  2DXB B;  1V29 B;  2CZ0 B;  2ZPE B;  3HHT B;  3A8L B;  3A8M B;  3X25 B; 
#chains in the Genus database with same CATH topology
 1URC B;  2QF7 A;  3K7A M;  2BS2 A;  1PKD B;  4FX3 B;  1N4M A;  2WFY B;  4JX5 A;  4F7N B;  4EOM B;  4CFU D;  1UNH D;  2ZPF B;  4ELJ A;  4BCO B;  2CYZ B;  3QYB A;  2CZ7 B;  5HNB B;  3BLH B;  2ZPH B;  2ZZD B;  1OKV B;  3A8H B;  4EOJ B;  3BLQ B;  1H25 B;  4BCH B;  1O9K B;  2C5O B;  4OB0 B;  5EJC A;  4HNT A;  3MY5 B;  1UNL D;  2V22 B;  1UGP B;  2WJ9 A;  5FGK B;  2ZPI B;  4BCQ D;  3WVD B;  4CFV B;  4G6L B;  4BCM D;  4EOS B;  2IN3 A;  4Z6Y A;  4NST B;  4ROC A;  3A8G B;  2W99 A;  4BY7 X;  5IDP B;  1H24 B;  4EOI B;  2I53 A;  3MY1 B;  4AKI A;  2I40 B;  4EOP B;  3POM A;  5LMK B;  2UZE B;  1AD6 A;  2CZ1 B;  5CEI B;  1GUX A;  4CRL B;  2QGS A;  3VKH A;  2C5V B;  4CFW B;  4BCI B;  3G33 B;  4YOZ A;  2WMA B;  2C6T B;  2BS3 A;  3A8O B;  5ICP B;  3VYH B;  1IRE B;  2DXB B;  1V29 B;  3EOC B;  2DXC B;  5L2W B;  2QQ8 A;  2BS4 A;  5LQF B;  3BG5 A;  4BCF B;  4BCN D;  2ZPB B;  3EID B;  4YC3 B;  1OL2 B;  2C5N B;  4OR5 B;  3HHT B;  5HQ0 B;  2IVX A;  4BCJ B;  1XO2 A;  2PJQ A;  4HL4 A;  3DTO A;  4KRC B;  2QDY B;  2EUF A;  2WPA B;  1QMZ B;  3TNH B;  4BCK B;  2CCH B;  2PMI B;  5CYI B;  4AKG A;  4TTH A;  1H1R B;  3BHT B;  2CZ0 B;  1P5E B;  2LW4 A;  1H4L D;  3MI9 B;  2ZPG B;  2DME A;  3BLR B;  1UGS B;  1H1P B;  2WEV B;  4OB3 B;  4CXA B;  3TNI B;  1ENW A;  2PHG A;  2G77 A;  4F6U B;  4MIM A;  1JOW A;  4IMY B;  4BCG B;  2UZL B;  3BHV B;  2KR6 A;  3WVE B;  3HBL A;  4F7J B;  4BXX X;  2CCI B;  3X26 B;  3DL1 A;  4ROE A;  2W9Z A;  4MFE A;  3A8L B;  2BKZ B;  4BCQ B;  3TW6 A;  1H28 B;  5HBE B;  3VYG B;  2PK2 A;  4EON B;  2UZD B;  1BU2 A;  4BCM B;  1W98 B;  2ZCF B;  3F5X B;  1JSU B;  4YOO A;  4UN0 A;  3TW7 A;  1QLB A;  1FKM A;  2DD4 B;  1FIN B;  3QWL A;  2WHB B;  5BNJ B;  1G3N C;  1TFB A;  1OI9 B;  4ELL A;  3NDQ A;  1GY3 B;  1H26 B;  1E9H B;  1JKW A;  4OB2 B;  4EOK B;  2R7G A;  5HBJ B;  4ZGE B;  1H1S B;  3QHR B;  1O9K A;  5HVY B;  1OIY B;  5HBH B;  3BHU B;  4EOL B;  3KHI A;  3BG3 A;  1UGR B;  2QDJ A;  4HNV A;  4MFD A;  4FM4 B;  3DOG B;  1AHJ B;  2IW9 B;  1GH6 B;  4BBR M;  4F6W B;  2UZB B;  4JX4 A;  3LQ5 B;  3QHW B;  2C5X B;  2B9R A;  5ACB A;  1H1Q B;  3B57 A;  4F6S B;  1GUX B;  2JGZ B;  3A8M B;  3TNW B;  4AKH A;  1OKW B;  4ROD A;  3O0G D;  2F2C A;  1FVV B;  1ZP2 A;  3QZ5 B;  2WIH B;  3QYH B;  3TN8 B;  4CFU B;  2C4G B;  2WXV B;  4ZGJ B;  4OGR B;  2G9X B;  3H4C A;  3HZJ A;  4EOQ B;  2PK9 B;  4CFN B;  3DDQ B;  4HLQ A;  1OIU B;  2W9F A;  3VKG A;  3M03 A;  4F7L B;  5DQV A;  3QXE B;  4OB1 B;  3QYG B;  4EOO B;  2D0Q B;  2DD5 B;  2DPP B;  4EC9 B;  2W2H A;  2AHJ B;  2CZ6 B;  3MIA B;  3RGF B;  4BCP B;  4EC8 B;  4CFM B;  3PO3 S;  1E7P A;  2BPM B;  2ZPE B;  4YOS A;  3HB9 A;  2UUE B;  1D3U B;  4LOC A;  3DDP B;  4M6V A;  4JX6 A;  2WMB B;  3DJB A;  1UNG D;  1OL1 B;  1AIS B;  4Y72 B;  3GTM S;  2KMG A;  4EOR B;  2W96 A;  1VYW B;  3X20 B;  3X25 B;  1F5Q B;  4F7S B;  1VOL A;  4II5 B;  4HNU A;  3BG9 A;  1KXU A;  3HO8 A;  4I3Z B;  4ZGD B;  5IDN B;  4BBS M;  4F70 B;  5DQW A;  5IF1 B;  5I5Z B;  3QZ9 B;  5EFQ B;  1OGU B;  3X28 B;  4QSH A;  2X1N B;  2CJM B;  2QFZ A;  1H27 B;  1VIN A;  5IHY A;  4BY1 X;  4BCN B;  4AI6 A;  3QYE A;  1UGQ B;  1JST B;  2IW8 B;  4KRD B;  4CFX B;  1TD6 A;  3X24 B;  2IW6 B;  2WIP B;  3EJ1 B;  4NC6 A;  1C9B A; 
#chains in the Genus database with same CATH homology
 3VKG A;  3VYG B;  2QF7 A;  2DXC B;  3QXE B;  4OB1 B;  3QYG B;  2BS2 A;  2QQ8 A;  2BS4 A;  2D0Q B;  2ZCF B;  2DD5 B;  3BG5 A;  2DPP B;  3TW7 A;  1QLB A;  4JX5 A;  2AHJ B;  2CZ6 B;  1FKM A;  2ZPB B;  2DD4 B;  2ZPF B;  1E7P A;  2ZPE B;  4ELJ A;  3HHT B;  3QWL A;  3HB9 A;  2CYZ B;  3QYB A;  2CZ7 B;  4HL4 A;  2ZPH B;  2ZZD B;  4LOC A;  3A8H B;  2QDY B;  4M6V A;  4JX6 A;  4OB0 B;  4OB2 B;  5EJC A;  4HNT A;  2KMG A;  4ZGE B;  4AKG A;  3X20 B;  2CZ0 B;  3X25 B;  1UGP B;  2WJ9 A;  3KHI A;  3BG3 A;  1UGR B;  2ZPG B;  2ZPI B;  1UGS B;  3WVD B;  4OB3 B;  2QDJ A;  4HNV A;  4MFD A;  4FM4 B;  4HNU A;  3BG9 A;  3HO8 A;  1AHJ B;  4BBR M;  4ZGD B;  4Z6Y A;  4BBS M;  3A8G B;  4JX4 A;  2G77 A;  3QZ9 B;  4MIM A;  3X28 B;  4AKI A;  4QSH A;  2KR6 A;  3A8M B;  4AKH A;  2CZ1 B;  2QFZ A;  3WVE B;  3HBL A;  3QZ5 B;  3VKH A;  3QYH B;  4AI6 A;  3QYE A;  1UGQ B;  3X26 B;  4ZGJ B;  3DL1 A;  3H4C A;  2BS3 A;  3A8O B;  3X24 B;  3HZJ A;  3VYH B;  1IRE B;  4NC6 A;  4MFE A;  2DXB B;  1V29 B;  3A8L B;  3TW6 A;  4HLQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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