2KMGA

The structure of the klca and ardb proteins show a novel fold and antirestriction activity against type i dna restriction systems in vivo but not in vitro
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
142
structure length
142
Chain Sequence
MNTEEQPVTASLVAEAQRLDFLPTYFGPRLMMRGEALVYAWMRRLCERYNGAYWHYYALSDGGFYMAPDLAGRLEIEVNGNGFRGELSADAAGIVATLFALGQLAAEIADTDAADALIDRYHFLRGFAAGHPEAAAIYRAID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro
pubmed doi rcsb
molecule tags Gene regulation
source organism Bordetella pertussis
molecule keywords KlcA
total genus 31
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2009-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03230 Antirestrict Antirestriction protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.120 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2kmgA00
2WJ9A 2KMGA
chains in the Genus database with same CATH superfamily
3WVDB 4OR5B 2AHJB 1TFBA 3WVEB 2IW8B 4YC3B 3VYGB 3QYBA 2BS4A 4F6WB 4OB1B 2IW9B 2QDYB 4ZGJB 1IREB 2ZPHB 4BBRM 3VKHA 3BHUB 2C5XB 2DXCB 4ZGDB 2WPAB 1VYWB 4CRLB 3TW7A 1E9HB 2W2HA 3QXEB 4BBSM 4OB0B 5CYIB 4CFXB 2JGZB 3X26B 1P5EB 2CJMB 1UGSB 1UNGD 2PK2A 1OKVB 4CFNB 1H1PB 4EC8B 3BLQB 4BCNB 1O9KA 4OB3B 3X28B 4BCFB 5IHYA 3RGFB 1JSUB 4F70B 4JX6A 3HBLA 1QMZB 4ZGEB 4EC9B 3A8LB 4HL4A 2C5VB 5DQVA 4BY7X 2WMAB 2CYZB 1QLBA 2CZ1B 3BG3A 3GTMS 2B9RA 4BCPB 4EOJB 1OGUB 4YOOA 2CZ6B 1UGQB 3BLHB 3QYHB 2WFYB 4EOKB 4CFWB 2W96A 4FM4B 1UGPB 5IF1B 2PHGA 1H1RB 3O0GD 4CFVB 2BS2A 3VYHB 4ROCA 1XO2A 1H1QB 4OB2B 3HHTB 4MFEA 2IVXA 3X24B 3PO3S 2DPPB 3TW6A 1D3UB 4BCMD 2DMEA 3HZJA 1VINA 1H25B 4BXXX 2C5OB 3POMA 3EJ1B 2CZ0B 4NC6A 5HBJB 2WJ9A 5ACBA 4TTHA 1C9BA 3BLRB 3HO8A 2W9FA 3G33B 4EONB 4EORB 4CFMB 4EOPB 2V22B 2BS3A 2I53A 4BCHB 1H4LD 2QQ8A 4BCOB 2D0QB 4BCGB 2UZEB 3DDPB 3H4CA 1JSTB 3EOCB 3KHIA 2PJQA 1UNHD 2QGSA 2PMIB 3DDQB 1FINB 1GH6B 2ZPBB 4HNTA 2ZCFB 2KMGA 4ROEA 3QWLA 1JOWA 4M6VA 3LQ5B 2C6TB 3TN8B 2C4GB 5CEIB 4I3ZB 4BCIB 4KRCB 1H27B 4AKHA 2ZPGB 2EUFA 3DOGB 3BG5A 3QZ9B 1FKMA 4QSHA 2LW4A 3HB9A 2CZ7B 4F7NB 3EIDB 3MY5B 1OL1B 4NSTB 2WIPB 1ENWA 1OIYB 2W99A 4AKIA 4BCQB 4YOZA 1F5QB 4BCQD 2X1NB 5HQ0B 2UZDB 5IDPB 1E7PA 1AHJB 2KR6A 4RODA 4Z6YA 2UUEB 2PK9B 1OI9B 5FGKB 1H26B 1VOLA 5HNBB 3QYEA 3F5XB 4IMYB 1O9KB 3BG9A 4BCMB 5I5ZB 4FX3B 2F2CA 3MI9B 3QYGB 3TNWB 1ZP2A 3BHVB 1V29B 4EOQB 2CCHB 2ZPIB 2UZBB 2WEVB 2ZZDB 2WIHB 3K7AM 4F7JB 2QF7A 4LOCA 4MIMA 3DTOA 1G3NC 2WHBB 2W9ZA 4UN0A 4BCJB 3DL1A 1N4MA 4ELLA 2DXBB 4EOIB 5EJCA 2G9XB 4II5B 3TNHB 4JX5A 4F7LB 3M03A 1UGRB 5L2WB 2ZPEB 1OL2B 5BNJB 3A8OB 3DJBA 2BPMB 2CCIB 1GUXA 4EOLB 2C5NB 4BCKB 4BCND 4HNUA 4AI6A 3MY1B 3MIAB 2WMBB 1AD6A 5HBEB 3QHRB 5IDNB 4F6UB 3X20B 2DD4B 4HNVA 1H24B 2G77A 4MFDA 4HLQA 1TD6A 2QFZA 1BU2A 1H28B 5LQFB 4CFUB 3A8HB 4CFUD 2DD5B 2IN3A 2R7GA 1JKWA 1H1SB 4Y72B 3NDQA 2QDJA 4ELJA 4AKGA 5EFQB 4F6SB 3BHTB 4EOOB 4KRDB 3QZ5B 5HBHB 1UNLD 2BKZB 1KXUA 4JX4A 1OIUB 3X25B 1W98B 1PKDB 5ICPB 4OGRB 3B57A 2ZPFB 1OKWB 4BY1X 3A8MB 4F7SB 3VKGA 5LMKB 2I40B 4YOSA 4G6LB 3TNIB 5DQWA 3A8GB 1FVVB 1GUXB 2IW6B 1GY3B 3QHWB 5HVYB 2WXVB 2UZLB 1AISB 4CXAB 1URCB 4EOMB 4EOSB
chains in the Genus database with same CATH topology
2DXBB 3WVDB 2AHJB 3BG5A 5EJCA 3WVEB 3QZ9B 1FKMA 4JX5A 4QSHA 2BS2A 3HB9A 3VYHB 3VYGB 1UGRB 3QYBA 2BS4A 2CZ7B 2ZPEB 4OB1B 2QDYB 4ZGJB 3A8OB 4OB2B 1IREB 3HHTB 2ZPHB 4BBRM 3VKHA 4MFEA 2DXCB 3X24B 2DPPB 3TW6A 4ZGDB 4AKIA 3HZJA 4HNUA 4AI6A 3TW7A 2CZ0B 1E7PA 3X20B 2DD4B 4BBSM 1AHJB 3QXEB 2KR6A 4NC6A 4Z6YA 2WJ9A 4HNVA 4OB0B 3X26B 2G77A 4MFDA 4HLQA 1UGSB 2QFZA 3HO8A 3QYEA 3BG9A 3A8HB 4OB3B 3X28B 2DD5B 2BS3A 2QQ8A 3QYGB 2QDJA 4ELJA 4AKGA 2D0QB 3QZ5B 4JX6A 3HBLA 3H4CA 4ZGEB 3A8LB 4HL4A 1V29B 4JX4A 3X25B 3KHIA 2ZPFB 2ZPIB 2CYZB 1QLBA 2CZ1B 3A8MB 3BG3A 3VKGA 2ZPBB 2ZZDB 4HNTA 2ZCFB 2KMGA 3QWLA 2QF7A 4M6VA 3A8GB 2CZ6B 1UGQB 3QYHB 4LOCA 4MIMA 4AKHA 2ZPGB 4FM4B 1UGPB 3DL1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WJ9 A;  2KMG A; 
#chains in the Genus database with same CATH topology
 3WVD B;  4OR5 B;  2AHJ B;  1TFB A;  3WVE B;  2IW8 B;  4YC3 B;  3VYG B;  3QYB A;  2BS4 A;  4F6W B;  4OB1 B;  2IW9 B;  2QDY B;  4ZGJ B;  1IRE B;  2ZPH B;  4BBR M;  3VKH A;  3BHU B;  2C5X B;  2DXC B;  4ZGD B;  2WPA B;  1VYW B;  4CRL B;  3TW7 A;  1E9H B;  2W2H A;  3QXE B;  4BBS M;  4OB0 B;  5CYI B;  4CFX B;  2JGZ B;  3X26 B;  1P5E B;  2CJM B;  1UGS B;  1UNG D;  2PK2 A;  1OKV B;  4CFN B;  1H1P B;  4EC8 B;  3BLQ B;  4BCN B;  1O9K A;  4OB3 B;  3X28 B;  4BCF B;  5IHY A;  3RGF B;  1JSU B;  4F70 B;  4JX6 A;  3HBL A;  1QMZ B;  4ZGE B;  4EC9 B;  3A8L B;  4HL4 A;  2C5V B;  5DQV A;  4BY7 X;  2WMA B;  2CYZ B;  1QLB A;  2CZ1 B;  3BG3 A;  3GTM S;  2B9R A;  4BCP B;  4EOJ B;  1OGU B;  4YOO A;  2CZ6 B;  1UGQ B;  3BLH B;  3QYH B;  2WFY B;  4EOK B;  4CFW B;  2W96 A;  4FM4 B;  1UGP B;  5IF1 B;  2PHG A;  1H1R B;  3O0G D;  4CFV B;  2BS2 A;  3VYH B;  4ROC A;  1XO2 A;  1H1Q B;  4OB2 B;  3HHT B;  4MFE A;  2IVX A;  3X24 B;  3PO3 S;  2DPP B;  3TW6 A;  1D3U B;  4BCM D;  2DME A;  3HZJ A;  1VIN A;  1H25 B;  4BXX X;  2C5O B;  3POM A;  3EJ1 B;  2CZ0 B;  4NC6 A;  5HBJ B;  2WJ9 A;  5ACB A;  4TTH A;  1C9B A;  3BLR B;  3HO8 A;  2W9F A;  3G33 B;  4EON B;  4EOR B;  4CFM B;  4EOP B;  2V22 B;  2BS3 A;  2I53 A;  4BCH B;  1H4L D;  2QQ8 A;  4BCO B;  2D0Q B;  4BCG B;  2UZE B;  3DDP B;  3H4C A;  1JST B;  3EOC B;  3KHI A;  2PJQ A;  1UNH D;  2QGS A;  2PMI B;  3DDQ B;  1FIN B;  1GH6 B;  2ZPB B;  4HNT A;  2ZCF B;  2KMG A;  4ROE A;  3QWL A;  1JOW A;  4M6V A;  3LQ5 B;  2C6T B;  3TN8 B;  2C4G B;  5CEI B;  4I3Z B;  4BCI B;  4KRC B;  1H27 B;  4AKH A;  2ZPG B;  2EUF A;  3DOG B;  3BG5 A;  3QZ9 B;  1FKM A;  4QSH A;  2LW4 A;  3HB9 A;  2CZ7 B;  4F7N B;  3EID B;  3MY5 B;  1OL1 B;  4NST B;  2WIP B;  1ENW A;  1OIY B;  2W99 A;  4AKI A;  4BCQ B;  4YOZ A;  1F5Q B;  4BCQ D;  2X1N B;  5HQ0 B;  2UZD B;  5IDP B;  1E7P A;  1AHJ B;  2KR6 A;  4ROD A;  4Z6Y A;  2UUE B;  2PK9 B;  1OI9 B;  5FGK B;  1H26 B;  1VOL A;  5HNB B;  3QYE A;  3F5X B;  4IMY B;  1O9K B;  3BG9 A;  4BCM B;  5I5Z B;  4FX3 B;  2F2C A;  3MI9 B;  3QYG B;  3TNW B;  1ZP2 A;  3BHV B;  1V29 B;  4EOQ B;  2CCH B;  2ZPI B;  2UZB B;  2WEV B;  2ZZD B;  2WIH B;  3K7A M;  4F7J B;  2QF7 A;  4LOC A;  4MIM A;  3DTO A;  1G3N C;  2WHB B;  2W9Z A;  4UN0 A;  4BCJ B;  3DL1 A;  1N4M A;  4ELL A;  2DXB B;  4EOI B;  5EJC A;  2G9X B;  4II5 B;  3TNH B;  4JX5 A;  4F7L B;  3M03 A;  1UGR B;  5L2W B;  2ZPE B;  1OL2 B;  5BNJ B;  3A8O B;  3DJB A;  2BPM B;  2CCI B;  1GUX A;  4EOL B;  2C5N B;  4BCK B;  4BCN D;  4HNU A;  4AI6 A;  3MY1 B;  3MIA B;  2WMB B;  1AD6 A;  5HBE B;  3QHR B;  5IDN B;  4F6U B;  3X20 B;  2DD4 B;  4HNV A;  1H24 B;  2G77 A;  4MFD A;  4HLQ A;  1TD6 A;  2QFZ A;  1BU2 A;  1H28 B;  5LQF B;  4CFU B;  3A8H B;  4CFU D;  2DD5 B;  2IN3 A;  2R7G A;  1JKW A;  1H1S B;  4Y72 B;  3NDQ A;  2QDJ A;  4ELJ A;  4AKG A;  5EFQ B;  4F6S B;  3BHT B;  4EOO B;  4KRD B;  3QZ5 B;  5HBH B;  1UNL D;  2BKZ B;  1KXU A;  4JX4 A;  1OIU B;  3X25 B;  1W98 B;  1PKD B;  5ICP B;  4OGR B;  3B57 A;  2ZPF B;  1OKW B;  4BY1 X;  3A8M B;  4F7S B;  3VKG A;  5LMK B;  2I40 B;  4YOS A;  4G6L B;  3TNI B;  5DQW A;  3A8G B;  1FVV B;  1GUX B;  2IW6 B;  1GY3 B;  3QHW B;  5HVY B;  2WXV B;  2UZL B;  1AIS B;  4CXA B;  1URC B;  4EOM B;  4EOS B; 
#chains in the Genus database with same CATH homology
 2DXB B;  3WVD B;  2AHJ B;  3BG5 A;  5EJC A;  3WVE B;  3QZ9 B;  1FKM A;  4JX5 A;  4QSH A;  2BS2 A;  3HB9 A;  3VYH B;  3VYG B;  1UGR B;  3QYB A;  2BS4 A;  2CZ7 B;  2ZPE B;  4OB1 B;  2QDY B;  4ZGJ B;  3A8O B;  4OB2 B;  1IRE B;  3HHT B;  2ZPH B;  4BBR M;  3VKH A;  4MFE A;  2DXC B;  3X24 B;  2DPP B;  3TW6 A;  4ZGD B;  4AKI A;  3HZJ A;  4HNU A;  4AI6 A;  3TW7 A;  2CZ0 B;  1E7P A;  3X20 B;  2DD4 B;  4BBS M;  1AHJ B;  3QXE B;  2KR6 A;  4NC6 A;  4Z6Y A;  2WJ9 A;  4HNV A;  4OB0 B;  3X26 B;  2G77 A;  4MFD A;  4HLQ A;  1UGS B;  2QFZ A;  3HO8 A;  3QYE A;  3BG9 A;  3A8H B;  4OB3 B;  3X28 B;  2DD5 B;  2BS3 A;  2QQ8 A;  3QYG B;  2QDJ A;  4ELJ A;  4AKG A;  2D0Q B;  3QZ5 B;  4JX6 A;  3HBL A;  3H4C A;  4ZGE B;  3A8L B;  4HL4 A;  1V29 B;  4JX4 A;  3X25 B;  3KHI A;  2ZPF B;  2ZPI B;  2CYZ B;  1QLB A;  2CZ1 B;  3A8M B;  3BG3 A;  3VKG A;  2ZPB B;  2ZZD B;  4HNT A;  2ZCF B;  2KMG A;  3QWL A;  2QF7 A;  4M6V A;  3A8G B;  2CZ6 B;  1UGQ B;  3QYH B;  4LOC A;  4MIM A;  4AKH A;  2ZPG B;  4FM4 B;  1UGP B;  3DL1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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