2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Endocytosis/exocytosis
source organism Homo sapiens
publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
molecule keywords Formin-binding protein 1
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
4FZSA 1I4LA 4NSWA 4DCNC 1WDZA 2D1LA 2C08A 1I4TA 1I4DA 2YKTA 3HAHA 3Q0KA 3Q84A 4BNEA 4NQIA 2Q12A 3QNIA 3ACOA 3LLLA 5C5BA 3CAZA 3OK8A 1X04A 1ZWWA 2ELBA 3ABHA 4ATMA 2X3WA 3PLTA 2EFLA 2X3XA 2Z0VA 1URUA 3M3WA 3SYVA 1X03A 2Z0OA 2EFKA 2X3VA 4WPEA 2RAIA 2Z0NA 3I2WA 2D4CA 3HAIA 2RAJA 4I1QA 5C5BB 3QWEA 1I49A 4DYLA 1Y2OA 3HAJA 2FICA 4H8SA 4AKVA 4WPCA 2V0OA 4AVMA 2RAKA 3QE6A 3SOGA 3G9GA 3DYTA 2Q13A
chains in the Genus database with same CATH superfamily
4AZCA 1WDZA 1TQSA 3DX4A 1OAOA 1QWNA 3O3NB 2F1BA 4IM3A 4ATMA 3PLTA 3EJTA 3KAVA 1GNTA 3I39X 3T48A 4HR1B 2OW6A 1PS3A 4AZ6A 4E3CA 2YI9A 3EJRA 2YKTA 3DX3A 1TQVA 3DX0A 4EZVA 3VEAA 4R5IA 4JWIA 2RAJA 3QA8A 2FICA 4PO2A 5KBPA 3KDRA 3BUDA 2ND0A 4NSWA 4DCNC 1I4DA 2F7QA 5E84A 4JL9A 3DPQA 2RT6A 1X03A 3EJPA 3DPPA 4IWOA 5C5BB 3DDFA 3FD9A 3ZEDA 4F00A 4FM3A 2JNKA 2OBLA 2YLLA 4BNEA 1SU7A 2ZXQA 3CAZA 4EZQA 1QX1A 2F1AA 2WYIA 2X3VA 4WPEA 1E9VA 4JWEA 4UDYX 3BUPA 3GI7A 1DKYA 2ND1A 4FZSA 1I4LA 4NQIA 2NCZA 3O3OB 2X3WA 2EFLA 1GNLA 3ERCC 2ALWA 2KHOA 3F7WA 3BVWA 3CVRA 2YIAA 3OWGA 2F7RA 4HR1A 2GAFD 3C7NA 1W9MA 4UDXX 1X04A 3CV5A 3I01A 3M3WA 4G6QA 1GN9A 1DKXA 2LXYA 2N3KA 3RPMA 1O7DC 1I49A 4H6IA 4R5GA 3D52A 4R5LA 3QE6A 3SOGA 4IWQA 2PMRA 1SUFA 2LM0A 1YWMA 3OK8A 4D8JA 4E81A 4AZIA 4EZUA 4AZBA 3D2EA 4EZZA 3I2WA 4HY9A 4FZOA 2D4CA 4HYBA 2WINM 2MI7A 3DYTA 4EZPA 3Q0KA 4H6HA 3HAHA 5C5BA 3EJSA 3BUQA 3EJQA 1ZWWA 3ABHA 4F01A 3BVTA 3ER8C 3ER9B 5FIGA 2YIBA 1OA1A 2YL5A 3G9GA 4IM0A 2Q13A 1LQ7A 1TQUA 4AZGA 1HXKA 3BUIA 5TKYA 3ACOA 4AZ5A 3D50A 2Z0OA 3L3PA 3RV0A 1R34A 2V0OA 2F7PA 3LVTA 3O3MB 3BVXA 3CZNA 3CZSA 2Z0VA 4JWDA 3T49A 2QXLA 3DPOA 1R33A 2EFKA 2GF4A 4B9QA 3B51X 4AZ7A 1Y2OA 3HAJA 4AKVA 1SU8A 3BVVA 2X5CA 4FZPA 3D4YA 3BUBA 1O7DB 4JN4A 3OHXM 2YL8A 3KAWA 2PY6A 4KIKA 3D51A 1U00A 4R5KA 4EZRA 1JQKA 2OO2A 3DDGA 2YL9A 3UITA 1ZYLA 3Q84A 4IM2A 4KIKB 1OA0A 3QNJA 2YLAA 4AZCB 3DX1A 3HAIA 1UPXA 2OZNB 3QWEA 4DYLA 3DX2A 2WYHA 4M0MA 2QKWA 2RAKA 2C08A 3QNIA 2F7OA 3BVUA 2FYVA 1MJGA 3L3OM 2Z8YA 2JNSA 2X3XA 3SYVA 1E2UA 2RAIA 4I1QA 4H8SA 4EZXA 4EZWA 2OBMA 4R5JA 3B52X 4JWCA 1DKZA 3RV1A 2ELBA 3LMFA 5FLEX 3T46A 3VKHA 1HTYA 2YIVX 3VEBA 2Z0NA 2GA9D 4JLCA 2QFFA 4NPHA 1TQWA 3T4AG 2OW7A 3LLLA 1QWUA 1R5EA 4IW0A 2YL6A 4IWPA 4EZNA 1HWWA 3CKDA 4WPCA 2EWFA 4EZOA 2O0I1 3T47A 4JNFA 3D2FA 2D1LA 1I4TA 2Q12A 1E1DA 4AZHA 2YI8A 1TQTA 4EZSA 3BLBA 4JNEA 2F18A 1URUA 1SU6A 3B53X 3I04A 2EX3B 4EZYA 4EZTA 4AVMA 3EJUA 3A98A 3D4ZA
chains in the Genus database with same CATH topology
4FZSA 1I4LA 4NSWA 4DCNC 1WDZA 2D1LA 2C08A 1I4TA 1I4DA 2YKTA 3HAHA 3Q0KA 3Q84A 4BNEA 4NQIA 2Q12A 3QNIA 3ACOA 3LLLA 5C5BA 3CAZA 3OK8A 1X04A 1ZWWA 2ELBA 3ABHA 4ATMA 2X3WA 3PLTA 2EFLA 2X3XA 2Z0VA 1URUA 3M3WA 3SYVA 1X03A 2Z0OA 2EFKA 2X3VA 4WPEA 2RAIA 2Z0NA 3I2WA 2D4CA 3HAIA 2RAJA 4I1QA 5C5BB 3QWEA 1I49A 4DYLA 1Y2OA 3HAJA 2FICA 4H8SA 4AKVA 4WPCA 2V0OA 4AVMA 2RAKA 3QE6A 3SOGA 3G9GA 3DYTA 2Q13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FZS A;  1I4L A;  4NSW A;  4DCN C;  1WDZ A;  2D1L A;  2C08 A;  1I4T A;  1I4D A;  2YKT A;  3HAH A;  3Q0K A;  3Q84 A;  4BNE A;  4NQI A;  2Q12 A;  3QNI A;  3ACO A;  3LLL A;  5C5B A;  3CAZ A;  3OK8 A;  1X04 A;  1ZWW A;  2ELB A;  3ABH A;  4ATM A;  2X3W A;  3PLT A;  2EFL A;  2X3X A;  2Z0V A;  1URU A;  3M3W A;  3SYV A;  1X03 A;  2Z0O A;  2EFK A;  2X3V A;  4WPE A;  2RAI A;  2Z0N A;  3I2W A;  2D4C A;  3HAI A;  2RAJ A;  4I1Q A;  5C5B B;  3QWE A;  1I49 A;  4DYL A;  1Y2O A;  3HAJ A;  2FIC A;  4H8S A;  4AKV A;  4WPC A;  2V0O A;  4AVM A;  2RAK A;  3QE6 A;  3SOG A;  3G9G A;  3DYT A;  2Q13 A; 
#chains in the Genus database with same CATH topology
 4AZC A;  1WDZ A;  1TQS A;  3DX4 A;  1OAO A;  1QWN A;  3O3N B;  2F1B A;  4IM3 A;  4ATM A;  3PLT A;  3EJT A;  3KAV A;  1GNT A;  3I39 X;  3T48 A;  4HR1 B;  2OW6 A;  1PS3 A;  4AZ6 A;  4E3C A;  2YI9 A;  3EJR A;  2YKT A;  3DX3 A;  1TQV A;  3DX0 A;  4EZV A;  3VEA A;  4R5I A;  4JWI A;  2RAJ A;  3QA8 A;  2FIC A;  4PO2 A;  5KBP A;  3KDR A;  3BUD A;  2ND0 A;  4NSW A;  4DCN C;  1I4D A;  2F7Q A;  5E84 A;  4JL9 A;  3DPQ A;  2RT6 A;  1X03 A;  3EJP A;  3DPP A;  4IWO A;  5C5B B;  3DDF A;  3FD9 A;  3ZED A;  4F00 A;  4FM3 A;  2JNK A;  2OBL A;  2YLL A;  4BNE A;  1SU7 A;  2ZXQ A;  3CAZ A;  4EZQ A;  1QX1 A;  2F1A A;  2WYI A;  2X3V A;  4WPE A;  1E9V A;  4JWE A;  4UDY X;  3BUP A;  3GI7 A;  1DKY A;  2ND1 A;  4FZS A;  1I4L A;  4NQI A;  2NCZ A;  3O3O B;  2X3W A;  2EFL A;  1GNL A;  3ERC C;  2ALW A;  2KHO A;  3F7W A;  3BVW A;  3CVR A;  2YIA A;  3OWG A;  2F7R A;  4HR1 A;  2GAF D;  3C7N A;  1W9M A;  4UDX X;  1X04 A;  3CV5 A;  3I01 A;  3M3W A;  4G6Q A;  1GN9 A;  1DKX A;  2LXY A;  2N3K A;  3RPM A;  1O7D C;  1I49 A;  4H6I A;  4R5G A;  3D52 A;  4R5L A;  3QE6 A;  3SOG A;  4IWQ A;  2PMR A;  1SUF A;  2LM0 A;  1YWM A;  3OK8 A;  4D8J A;  4E81 A;  4AZI A;  4EZU A;  4AZB A;  3D2E A;  4EZZ A;  3I2W A;  4HY9 A;  4FZO A;  2D4C A;  4HYB A;  2WIN M;  2MI7 A;  3DYT A;  4EZP A;  3Q0K A;  4H6H A;  3HAH A;  5C5B A;  3EJS A;  3BUQ A;  3EJQ A;  1ZWW A;  3ABH A;  4F01 A;  3BVT A;  3ER8 C;  3ER9 B;  5FIG A;  2YIB A;  1OA1 A;  2YL5 A;  3G9G A;  4IM0 A;  2Q13 A;  1LQ7 A;  1TQU A;  4AZG A;  1HXK A;  3BUI A;  5TKY A;  3ACO A;  4AZ5 A;  3D50 A;  2Z0O A;  3L3P A;  3RV0 A;  1R34 A;  2V0O A;  2F7P A;  3LVT A;  3O3M B;  3BVX A;  3CZN A;  3CZS A;  2Z0V A;  4JWD A;  3T49 A;  2QXL A;  3DPO A;  1R33 A;  2EFK A;  2GF4 A;  4B9Q A;  3B51 X;  4AZ7 A;  1Y2O A;  3HAJ A;  4AKV A;  1SU8 A;  3BVV A;  2X5C A;  4FZP A;  3D4Y A;  3BUB A;  1O7D B;  4JN4 A;  3OHX M;  2YL8 A;  3KAW A;  2PY6 A;  4KIK A;  3D51 A;  1U00 A;  4R5K A;  4EZR A;  1JQK A;  2OO2 A;  3DDG A;  2YL9 A;  3UIT A;  1ZYL A;  3Q84 A;  4IM2 A;  4KIK B;  1OA0 A;  3QNJ A;  2YLA A;  4AZC B;  3DX1 A;  3HAI A;  1UPX A;  2OZN B;  3QWE A;  4DYL A;  3DX2 A;  2WYH A;  4M0M A;  2QKW A;  2RAK A;  2C08 A;  3QNI A;  2F7O A;  3BVU A;  2FYV A;  1MJG A;  3L3O M;  2Z8Y A;  2JNS A;  2X3X A;  3SYV A;  1E2U A;  2RAI A;  4I1Q A;  4H8S A;  4EZX A;  4EZW A;  2OBM A;  4R5J A;  3B52 X;  4JWC A;  1DKZ A;  3RV1 A;  2ELB A;  3LMF A;  5FLE X;  3T46 A;  3VKH A;  1HTY A;  2YIV X;  3VEB A;  2Z0N A;  2GA9 D;  4JLC A;  2QFF A;  4NPH A;  1TQW A;  3T4A G;  2OW7 A;  3LLL A;  1QWU A;  1R5E A;  4IW0 A;  2YL6 A;  4IWP A;  4EZN A;  1HWW A;  3CKD A;  4WPC A;  2EWF A;  4EZO A;  2O0I 1;  3T47 A;  4JNF A;  3D2F A;  2D1L A;  1I4T A;  2Q12 A;  1E1D A;  4AZH A;  2YI8 A;  1TQT A;  4EZS A;  3BLB A;  4JNE A;  2F18 A;  1URU A;  1SU6 A;  3B53 X;  3I04 A;  2EX3 B;  4EZY A;  4EZT A;  4AVM A;  3EJU A;  3A98 A;  3D4Z A; 
#chains in the Genus database with same CATH homology
 4FZS A;  1I4L A;  4NSW A;  4DCN C;  1WDZ A;  2D1L A;  2C08 A;  1I4T A;  1I4D A;  2YKT A;  3HAH A;  3Q0K A;  3Q84 A;  4BNE A;  4NQI A;  2Q12 A;  3QNI A;  3ACO A;  3LLL A;  5C5B A;  3CAZ A;  3OK8 A;  1X04 A;  1ZWW A;  2ELB A;  3ABH A;  4ATM A;  2X3W A;  3PLT A;  2EFL A;  2X3X A;  2Z0V A;  1URU A;  3M3W A;  3SYV A;  1X03 A;  2Z0O A;  2EFK A;  2X3V A;  4WPE A;  2RAI A;  2Z0N A;  3I2W A;  2D4C A;  3HAI A;  2RAJ A;  4I1Q A;  5C5B B;  3QWE A;  1I49 A;  4DYL A;  1Y2O A;  3HAJ A;  2FIC A;  4H8S A;  4AKV A;  4WPC A;  2V0O A;  4AVM A;  2RAK A;  3QE6 A;  3SOG A;  3G9G A;  3DYT A;  2Q13 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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