2EFLA

Crystal structure of the efc domain of formin-binding protein 17
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
288
structure length
281
Chain Sequence
MSWGTELWDQFDNLEKHTQWGIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKEYKYTSCKAFISNLNEMNDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRRFERDCKEADRAQQYFEKMDADINVTKADVEKARQQAQIRHQMAEDSKADYSSILQKFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKAAESIDQKNDSQLVIEAYKSGFEPPGDIEFEDYT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
pubmed doi rcsb
molecule tags Endocytosis/exocytosis
source organism Homo sapiens
molecule keywords Formin-binding protein 1
total genus 116
structure length 281
sequence length 288
ec nomenclature
pdb deposition date 2007-02-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2eflA00
3OK8A 4WPEA 3I2WA 3DYTA 3LLLA 1I4TA 2X3VA 3G9GA 3ACOA 4DYLA 2Z0VA 4AVMA 2Z0OA 2C08A 4I1QA 2EFLA 4NSWA 1Y2OA 1ZWWA 4DCNC 2Z0NA 1X04A 2V0OA 4AKVA 3Q0KA 1X03A 3ABHA 3HAJA 4NQIA 2YKTA 2ELBA 3QNIA 3M3WA 4ATMA 3HAHA 3CAZA 3QWEA 4H8SA 1WDZA 2RAJA 2D1LA 4WPCA 2RAKA 3Q84A 1I49A 5C5BB 4BNEA 2Q12A 2RAIA 5C5BA 3HAIA 2X3XA 2FICA 3QE6A 2EFKA 2D4CA 2X3WA 3SYVA 2Q13A 3PLTA 4FZSA 1I4LA 1I4DA 1URUA 3SOGA
chains in the Genus database with same CATH superfamily
2YIVX 3BVUA 3O3MB 4JWIA 1TQTA 2V0OA 4PO2A 4H6IA 2PMRA 3EJPA 1JQKA 4EZSA 3VEBA 3Q84A 3EJRA 3SYVA 2EFKA 1R33A 4M0MA 2MI7A 3DX3A 3OK8A 1PS3A 4JL9A 2F7PA 2PY6A 4BNEA 1OA0A 2N3KA 3D4ZA 4FZSA 4EZTA 5C5BA 4AZ6A 3KAVA 4D8JA 4AZIA 3KAWA 1ZWWA 2ND0A 2WYHA 4DCNC 2GAFD 2YLLA 3T49A 3HAIA 4AZCA 3DX1A 3EJTA 2YIAA 4IM0A 3UITA 2LXYA 3BUBA 3L3OM 1E1DA 4I1QA 2EFLA 4EZVA 2F1BA 3DPOA 4WPCA 3T48A 3ER9B 1YWMA 3F7WA 1ZYLA 3ERCC 4EZRA 1HTYA 1W9MA 1TQUA 4UDXX 1SU7A 5FLEX 2Z0VA 2NCZA 3QNJA 4B9QA 2GA9D 4H6HA 3Q0KA 4HR1A 3QA8A 4EZXA 2YL5A 2EWFA 3QWEA 4JNEA 2LM0A 2OO2A 2Q13A 3D51A 3I01A 3BUPA 2F7RA 4F01A 1UPXA 4JN4A 1QX1A 2F7OA 2Z0NA 2OBLA 1SUFA 3BUDA 1WDZA 1I49A 4KIKA 2KHOA 2ND1A 1GNTA 4G6QA 2FICA 3D4YA 3D2EA 1SU8A 4AVMA 3B53X 1R5EA 1TQSA 3GI7A 3CZNA 1U00A 1QWNA 3QE6A 2Z8YA 2OW7A 4R5IA 3LLLA 1O7DB 3G9GA 2ALWA 4FZOA 2YL6A 4EZQA 2GF4A 1DKYA 3ZEDA 3M3WA 3HAHA 3CAZA 2FYVA 2RAJA 4AZ5A 4JWCA 3LMFA 3CKDA 4AZBA 4EZOA 3BVWA 3BUIA 1DKXA 2YI9A 2YIBA 4IWQA 4NSWA 2RT6A 3DX4A 1GNLA 3RV1A 1HXKA 2WINM 3DX2A 4HYBA 3VKHA 2ELBA 5E84A 2O0I1 2D1LA 2YL8A 3DPQA 3DPPA 3L3PA 1OA1A 3D2FA 3EJSA 2WYIA 1TQVA 3C7NA 2JNSA 4FZPA 2QXLA 3DX0A 3QNIA 5FIGA 3T4AG 3O3NB 3CVRA 5C5BB 4UDYX 4FM3A 1OAOA 1O7DC 2F18A 4IWPA 4E3CA 3SOGA 1E2UA 3I2WA 3I04A 2F1AA 3DYTA 2X3VA 3ER8C 3T47A 2Z0OA 4EZNA 4AKVA 2OZNB 1QWUA 4AZCB 4JNFA 3B51X 3T46A 4H8SA 2X3XA 3BVVA 3PLTA 3VEAA 4IW0A 2EX3B 4IM3A 1I4TA 3CZSA 2C08A 4JLCA 2YL9A 5KBPA 1X04A 3B52X 1GN9A 5TKYA 3DDGA 4JWDA 2OW6A 4EZWA 4R5KA 4R5JA 1URUA 3OWGA 3BLBA 2YLAA 1HWWA 4EZPA 4HR1B 2JNKA 3RPMA 1Y2OA 4AZ7A 4AZGA 4NQIA 3HAJA 2YKTA 4EZUA 3CV5A 4NPHA 1E9VA 3FD9A 2ZXQA 3OHXM 4IWOA 1TQWA 2QKWA 4DYLA 2F7QA 2QFFA 4HY9A 1SU6A 4KIKB 4ATMA 2YI8A 3D52A 2D4CA 3A98A 2OBMA 3EJUA 3RV0A 1DKZA 4WPEA 4JWEA 3EJQA 3O3OB 3BVXA 4F00A 3DDFA 3D50A 3KDRA 2Q12A 2RAIA 4EZZA 2X5CA 2X3WA 3BUQA 3BVTA 3I39X 3ACOA 3LVTA 4EZYA 4IM2A 4E81A 1R34A 1X03A 3ABHA 2RAKA 4R5LA 4R5GA 4AZHA 1MJGA 1LQ7A 1I4LA 1I4DA
chains in the Genus database with same CATH topology
3OK8A 4WPEA 3I2WA 3DYTA 3LLLA 1I4TA 2X3VA 3G9GA 3ACOA 4DYLA 2Z0VA 4AVMA 2Z0OA 2C08A 4I1QA 2EFLA 4NSWA 1Y2OA 1ZWWA 4DCNC 2Z0NA 1X04A 2V0OA 4AKVA 3Q0KA 1X03A 3ABHA 3HAJA 4NQIA 2YKTA 2ELBA 3QNIA 3M3WA 4ATMA 3HAHA 3CAZA 3QWEA 4H8SA 1WDZA 2RAJA 2D1LA 4WPCA 2RAKA 3Q84A 1I49A 5C5BB 4BNEA 2Q12A 2RAIA 5C5BA 3HAIA 2X3XA 2FICA 3QE6A 2EFKA 2D4CA 2X3WA 3SYVA 2Q13A 3PLTA 4FZSA 1I4LA 1I4DA 1URUA 3SOGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OK8 A;  4WPE A;  3I2W A;  3DYT A;  3LLL A;  1I4T A;  2X3V A;  3G9G A;  3ACO A;  4DYL A;  2Z0V A;  4AVM A;  2Z0O A;  2C08 A;  4I1Q A;  2EFL A;  4NSW A;  1Y2O A;  1ZWW A;  4DCN C;  2Z0N A;  1X04 A;  2V0O A;  4AKV A;  3Q0K A;  1X03 A;  3ABH A;  3HAJ A;  4NQI A;  2YKT A;  2ELB A;  3QNI A;  3M3W A;  4ATM A;  3HAH A;  3CAZ A;  3QWE A;  4H8S A;  1WDZ A;  2RAJ A;  2D1L A;  4WPC A;  2RAK A;  3Q84 A;  1I49 A;  5C5B B;  4BNE A;  2Q12 A;  2RAI A;  5C5B A;  3HAI A;  2X3X A;  2FIC A;  3QE6 A;  2EFK A;  2D4C A;  2X3W A;  3SYV A;  2Q13 A;  3PLT A;  4FZS A;  1I4L A;  1I4D A;  1URU A;  3SOG A; 
#chains in the Genus database with same CATH topology
 2YIV X;  3BVU A;  3O3M B;  4JWI A;  1TQT A;  2V0O A;  4PO2 A;  4H6I A;  2PMR A;  3EJP A;  1JQK A;  4EZS A;  3VEB A;  3Q84 A;  3EJR A;  3SYV A;  2EFK A;  1R33 A;  4M0M A;  2MI7 A;  3DX3 A;  3OK8 A;  1PS3 A;  4JL9 A;  2F7P A;  2PY6 A;  4BNE A;  1OA0 A;  2N3K A;  3D4Z A;  4FZS A;  4EZT A;  5C5B A;  4AZ6 A;  3KAV A;  4D8J A;  4AZI A;  3KAW A;  1ZWW A;  2ND0 A;  2WYH A;  4DCN C;  2GAF D;  2YLL A;  3T49 A;  3HAI A;  4AZC A;  3DX1 A;  3EJT A;  2YIA A;  4IM0 A;  3UIT A;  2LXY A;  3BUB A;  3L3O M;  1E1D A;  4I1Q A;  2EFL A;  4EZV A;  2F1B A;  3DPO A;  4WPC A;  3T48 A;  3ER9 B;  1YWM A;  3F7W A;  1ZYL A;  3ERC C;  4EZR A;  1HTY A;  1W9M A;  1TQU A;  4UDX X;  1SU7 A;  5FLE X;  2Z0V A;  2NCZ A;  3QNJ A;  4B9Q A;  2GA9 D;  4H6H A;  3Q0K A;  4HR1 A;  3QA8 A;  4EZX A;  2YL5 A;  2EWF A;  3QWE A;  4JNE A;  2LM0 A;  2OO2 A;  2Q13 A;  3D51 A;  3I01 A;  3BUP A;  2F7R A;  4F01 A;  1UPX A;  4JN4 A;  1QX1 A;  2F7O A;  2Z0N A;  2OBL A;  1SUF A;  3BUD A;  1WDZ A;  1I49 A;  4KIK A;  2KHO A;  2ND1 A;  1GNT A;  4G6Q A;  2FIC A;  3D4Y A;  3D2E A;  1SU8 A;  4AVM A;  3B53 X;  1R5E A;  1TQS A;  3GI7 A;  3CZN A;  1U00 A;  1QWN A;  3QE6 A;  2Z8Y A;  2OW7 A;  4R5I A;  3LLL A;  1O7D B;  3G9G A;  2ALW A;  4FZO A;  2YL6 A;  4EZQ A;  2GF4 A;  1DKY A;  3ZED A;  3M3W A;  3HAH A;  3CAZ A;  2FYV A;  2RAJ A;  4AZ5 A;  4JWC A;  3LMF A;  3CKD A;  4AZB A;  4EZO A;  3BVW A;  3BUI A;  1DKX A;  2YI9 A;  2YIB A;  4IWQ A;  4NSW A;  2RT6 A;  3DX4 A;  1GNL A;  3RV1 A;  1HXK A;  2WIN M;  3DX2 A;  4HYB A;  3VKH A;  2ELB A;  5E84 A;  2O0I 1;  2D1L A;  2YL8 A;  3DPQ A;  3DPP A;  3L3P A;  1OA1 A;  3D2F A;  3EJS A;  2WYI A;  1TQV A;  3C7N A;  2JNS A;  4FZP A;  2QXL A;  3DX0 A;  3QNI A;  5FIG A;  3T4A G;  3O3N B;  3CVR A;  5C5B B;  4UDY X;  4FM3 A;  1OAO A;  1O7D C;  2F18 A;  4IWP A;  4E3C A;  3SOG A;  1E2U A;  3I2W A;  3I04 A;  2F1A A;  3DYT A;  2X3V A;  3ER8 C;  3T47 A;  2Z0O A;  4EZN A;  4AKV A;  2OZN B;  1QWU A;  4AZC B;  4JNF A;  3B51 X;  3T46 A;  4H8S A;  2X3X A;  3BVV A;  3PLT A;  3VEA A;  4IW0 A;  2EX3 B;  4IM3 A;  1I4T A;  3CZS A;  2C08 A;  4JLC A;  2YL9 A;  5KBP A;  1X04 A;  3B52 X;  1GN9 A;  5TKY A;  3DDG A;  4JWD A;  2OW6 A;  4EZW A;  4R5K A;  4R5J A;  1URU A;  3OWG A;  3BLB A;  2YLA A;  1HWW A;  4EZP A;  4HR1 B;  2JNK A;  3RPM A;  1Y2O A;  4AZ7 A;  4AZG A;  4NQI A;  3HAJ A;  2YKT A;  4EZU A;  3CV5 A;  4NPH A;  1E9V A;  3FD9 A;  2ZXQ A;  3OHX M;  4IWO A;  1TQW A;  2QKW A;  4DYL A;  2F7Q A;  2QFF A;  4HY9 A;  1SU6 A;  4KIK B;  4ATM A;  2YI8 A;  3D52 A;  2D4C A;  3A98 A;  2OBM A;  3EJU A;  3RV0 A;  1DKZ A;  4WPE A;  4JWE A;  3EJQ A;  3O3O B;  3BVX A;  4F00 A;  3DDF A;  3D50 A;  3KDR A;  2Q12 A;  2RAI A;  4EZZ A;  2X5C A;  2X3W A;  3BUQ A;  3BVT A;  3I39 X;  3ACO A;  3LVT A;  4EZY A;  4IM2 A;  4E81 A;  1R34 A;  1X03 A;  3ABH A;  2RAK A;  4R5L A;  4R5G A;  4AZH A;  1MJG A;  1LQ7 A;  1I4L A;  1I4D A; 
#chains in the Genus database with same CATH homology
 3OK8 A;  4WPE A;  3I2W A;  3DYT A;  3LLL A;  1I4T A;  2X3V A;  3G9G A;  3ACO A;  4DYL A;  2Z0V A;  4AVM A;  2Z0O A;  2C08 A;  4I1Q A;  2EFL A;  4NSW A;  1Y2O A;  1ZWW A;  4DCN C;  2Z0N A;  1X04 A;  2V0O A;  4AKV A;  3Q0K A;  1X03 A;  3ABH A;  3HAJ A;  4NQI A;  2YKT A;  2ELB A;  3QNI A;  3M3W A;  4ATM A;  3HAH A;  3CAZ A;  3QWE A;  4H8S A;  1WDZ A;  2RAJ A;  2D1L A;  4WPC A;  2RAK A;  3Q84 A;  1I49 A;  5C5B B;  4BNE A;  2Q12 A;  2RAI A;  5C5B A;  3HAI A;  2X3X A;  2FIC A;  3QE6 A;  2EFK A;  2D4C A;  2X3W A;  3SYV A;  2Q13 A;  3PLT A;  4FZS A;  1I4L A;  1I4D A;  1URU A;  3SOG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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