2FICA

The crystal structure of the bar domain from human bin1/amphiphysin ii and its implications for molecular recognition
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
198
structure length
191
Chain Sequence
EQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of the BAR Domain from Human Bin1/Amphiphysin II and Its Implications for Molecular Recognition
pubmed doi rcsb
molecule tags Endocytosis/exocytosis, membrane protein
source organism Homo sapiens
molecule keywords Myc box-dependent-interacting protein 1
total genus 87
structure length 191
sequence length 198
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-12-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2ficA00
1Y2OA 2X3XA 5C5BB 2ELBA 3CAZA 3HAIA 1I4DA 2Q13A 2Q12A 2V0OA 2D1LA 2RAIA 4NQIA 1X03A 2X3VA 1I4TA 2EFKA 4AKVA 3SOGA 3G9GA 2YKTA 3ABHA 3HAHA 4ATMA 3QNIA 3M3WA 3ACOA 4FZSA 1I49A 2RAJA 2X3WA 2C08A 2RAKA 3I2WA 3OK8A 3SYVA 4DYLA 2Z0NA 2Z0OA 4AVMA 4DCNC 3LLLA 2EFLA 4NSWA 4WPEA 2FICA 3Q84A 3QWEA 1URUA 3QE6A 4H8SA 3DYTA 4BNEA 3HAJA 3Q0KA 5C5BA 4WPCA 1WDZA 1ZWWA 4I1QA 2D4CA 3PLTA 1I4LA 1X04A 2Z0VA
chains in the Genus database with same CATH superfamily
3UITA 3QNIA 2RAJA 3OK8A 3SYVA 4IWQA 3ERCC 4DCNC 4B9QA 4IWOA 2PMRA 3DPOA 4EZZA 3VEBA 3Q0KA 2OO2A 4H6IA 1TQTA 4AZ6A 2JNKA 1SU7A 2D1LA 1ZYLA 4EZNA 1I49A 3L3OM 3ER8C 1TQUA 3EJUA 3BVVA 2ZXQA 3BVXA 5C5BA 1ZWWA 2OBLA 3O3OB 3D51A 1PS3A 1LQ7A 1OA0A 4NQIA 3T49A 4EZXA 3EJQA 3ER9B 4AVMA 3FD9A 3CZNA 3ZEDA 2FICA 4AZCB 1MJGA 2D4CA 1X04A 2YI9A 3RPMA 3B53X 3BUPA 3HAHA 2X3WA 1O7DC 1E9VA 4FM3A 4JLCA 4JNEA 1HTYA 3T47A 2QXLA 4I1QA 1E2UA 2YL5A 3OHXM 2YKTA 4IM2A 5FIGA 2RAKA 2EWFA 4IW0A 3GI7A 3QNJA 3I39X 1TQSA 3DX1A 4R5IA 4AZ7A 2Z0VA 2X3XA 1O7DB 3CAZA 1OA1A 3D52A 2Q12A 2ALWA 4HR1B 1W9MA 2YL6A 4IWPA 2F7PA 3DPQA 4H6HA 4M0MA 4NSWA 3BUIA 2GAFD 2QFFA 3BUQA 3QA8A 4JNFA 3D4YA 1URUA 3DPPA 2PY6A 2ND1A 2JNSA 1Y2OA 4PO2A 2OW6A 4HYBA 3EJPA 3DX3A 2X3VA 4EZTA 2KHOA 5E84A 5KBPA 2WYHA 4KIKA 3DDGA 2WYIA 1HXKA 1QWNA 4F01A 3OWGA 3C7NA 4EZSA 3DX4A 3DYTA 3I2WA 1SU6A 2ELBA 3HAIA 3VKHA 1R33A 2YIBA 2MI7A 1GN9A 1GNLA 4F00A 1QWUA 2OZNB 2F18A 2Z0NA 3DDFA 2WINM 3RV1A 3BVUA 1JQKA 1I4DA 2YLAA 2YI8A 1I4TA 3D2FA 4IM3A 1DKXA 3CZSA 3KAWA 3KDRA 4ATMA 3M3WA 4JWIA 5FLEX 4EZYA 3CVRA 3BLBA 4AZGA 2X5CA 1I4LA 3BVTA 1X03A 3SOGA 2GA9D 3ABHA 3VEAA 2O0I1 1QX1A 2YL8A 3DX2A 4HY9A 4EZRA 3DX0A 2Q13A 1OAOA 4G6QA 4JL9A 3D2EA 2F7RA 4AZBA 4FZPA 2RT6A 3I04A 2GF4A 2EX3B 4JWCA 4E3CA 1DKYA 4R5GA 4R5JA 4R5KA 3BUBA 4EZPA 3LLLA 3EJSA 3QWEA 1TQWA 4NPHA 4WPCA 3A98A 2N3KA 5C5BB 1UPXA 2OBMA 1SU8A 4AKVA 4EZWA 3T46A 3RV0A 3T4AG 4FZSA 3CV5A 4DYLA 3CKDA 1YWMA 4JWEA 2EFLA 4AZHA 3L3PA 2NCZA 3BUDA 4EZUA 2QKWA 4H8SA 3D50A 4FZOA 4D8JA 3O3NB 4HR1A 2V0OA 2EFKA 2FYVA 3ACOA 5TKYA 3Q84A 4IM0A 2YLLA 1SUFA 2Z8YA 4UDYX 4EZQA 3O3MB 3G9GA 4JN4A 3LVTA 2YL9A 2Z0OA 4AZIA 4EZVA 2LM0A 2LXYA 1WDZA 3B51X 1E1DA 4E81A 3I01A 2RAIA 2YIVX 2F1BA 2F7OA 2OW7A 4EZOA 1DKZA 3LMFA 3T48A 2C08A 1R34A 3F7WA 1HWWA 2F7QA 3EJRA 4AZCA 3QE6A 4BNEA 3HAJA 2F1AA 4R5LA 4AZ5A 1R5EA 4JWDA 1TQVA 1GNTA 3EJTA 2YIAA 3KAVA 4UDXX 3BVWA 3D4ZA 4KIKB 4WPEA 2ND0A 1U00A 3B52X 3PLTA
chains in the Genus database with same CATH topology
1Y2OA 2X3XA 5C5BB 2ELBA 3CAZA 3HAIA 1I4DA 2Q13A 2Q12A 2V0OA 2D1LA 2RAIA 4NQIA 1X03A 2X3VA 1I4TA 2EFKA 4AKVA 3SOGA 3G9GA 2YKTA 3ABHA 3HAHA 4ATMA 3QNIA 3M3WA 3ACOA 4FZSA 1I49A 2RAJA 2X3WA 2C08A 2RAKA 3I2WA 3OK8A 3SYVA 4DYLA 2Z0NA 2Z0OA 4AVMA 4DCNC 3LLLA 2EFLA 4NSWA 4WPEA 2FICA 3Q84A 3QWEA 1URUA 3QE6A 4H8SA 3DYTA 4BNEA 3HAJA 3Q0KA 5C5BA 4WPCA 1WDZA 1ZWWA 4I1QA 2D4CA 3PLTA 1I4LA 1X04A 2Z0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y2O A;  2X3X A;  5C5B B;  2ELB A;  3CAZ A;  3HAI A;  1I4D A;  2Q13 A;  2Q12 A;  2V0O A;  2D1L A;  2RAI A;  4NQI A;  1X03 A;  2X3V A;  1I4T A;  2EFK A;  4AKV A;  3SOG A;  3G9G A;  2YKT A;  3ABH A;  3HAH A;  4ATM A;  3QNI A;  3M3W A;  3ACO A;  4FZS A;  1I49 A;  2RAJ A;  2X3W A;  2C08 A;  2RAK A;  3I2W A;  3OK8 A;  3SYV A;  4DYL A;  2Z0N A;  2Z0O A;  4AVM A;  4DCN C;  3LLL A;  2EFL A;  4NSW A;  4WPE A;  2FIC A;  3Q84 A;  3QWE A;  1URU A;  3QE6 A;  4H8S A;  3DYT A;  4BNE A;  3HAJ A;  3Q0K A;  5C5B A;  4WPC A;  1WDZ A;  1ZWW A;  4I1Q A;  2D4C A;  3PLT A;  1I4L A;  1X04 A;  2Z0V A; 
#chains in the Genus database with same CATH topology
 3UIT A;  3QNI A;  2RAJ A;  3OK8 A;  3SYV A;  4IWQ A;  3ERC C;  4DCN C;  4B9Q A;  4IWO A;  2PMR A;  3DPO A;  4EZZ A;  3VEB A;  3Q0K A;  2OO2 A;  4H6I A;  1TQT A;  4AZ6 A;  2JNK A;  1SU7 A;  2D1L A;  1ZYL A;  4EZN A;  1I49 A;  3L3O M;  3ER8 C;  1TQU A;  3EJU A;  3BVV A;  2ZXQ A;  3BVX A;  5C5B A;  1ZWW A;  2OBL A;  3O3O B;  3D51 A;  1PS3 A;  1LQ7 A;  1OA0 A;  4NQI A;  3T49 A;  4EZX A;  3EJQ A;  3ER9 B;  4AVM A;  3FD9 A;  3CZN A;  3ZED A;  2FIC A;  4AZC B;  1MJG A;  2D4C A;  1X04 A;  2YI9 A;  3RPM A;  3B53 X;  3BUP A;  3HAH A;  2X3W A;  1O7D C;  1E9V A;  4FM3 A;  4JLC A;  4JNE A;  1HTY A;  3T47 A;  2QXL A;  4I1Q A;  1E2U A;  2YL5 A;  3OHX M;  2YKT A;  4IM2 A;  5FIG A;  2RAK A;  2EWF A;  4IW0 A;  3GI7 A;  3QNJ A;  3I39 X;  1TQS A;  3DX1 A;  4R5I A;  4AZ7 A;  2Z0V A;  2X3X A;  1O7D B;  3CAZ A;  1OA1 A;  3D52 A;  2Q12 A;  2ALW A;  4HR1 B;  1W9M A;  2YL6 A;  4IWP A;  2F7P A;  3DPQ A;  4H6H A;  4M0M A;  4NSW A;  3BUI A;  2GAF D;  2QFF A;  3BUQ A;  3QA8 A;  4JNF A;  3D4Y A;  1URU A;  3DPP A;  2PY6 A;  2ND1 A;  2JNS A;  1Y2O A;  4PO2 A;  2OW6 A;  4HYB A;  3EJP A;  3DX3 A;  2X3V A;  4EZT A;  2KHO A;  5E84 A;  5KBP A;  2WYH A;  4KIK A;  3DDG A;  2WYI A;  1HXK A;  1QWN A;  4F01 A;  3OWG A;  3C7N A;  4EZS A;  3DX4 A;  3DYT A;  3I2W A;  1SU6 A;  2ELB A;  3HAI A;  3VKH A;  1R33 A;  2YIB A;  2MI7 A;  1GN9 A;  1GNL A;  4F00 A;  1QWU A;  2OZN B;  2F18 A;  2Z0N A;  3DDF A;  2WIN M;  3RV1 A;  3BVU A;  1JQK A;  1I4D A;  2YLA A;  2YI8 A;  1I4T A;  3D2F A;  4IM3 A;  1DKX A;  3CZS A;  3KAW A;  3KDR A;  4ATM A;  3M3W A;  4JWI A;  5FLE X;  4EZY A;  3CVR A;  3BLB A;  4AZG A;  2X5C A;  1I4L A;  3BVT A;  1X03 A;  3SOG A;  2GA9 D;  3ABH A;  3VEA A;  2O0I 1;  1QX1 A;  2YL8 A;  3DX2 A;  4HY9 A;  4EZR A;  3DX0 A;  2Q13 A;  1OAO A;  4G6Q A;  4JL9 A;  3D2E A;  2F7R A;  4AZB A;  4FZP A;  2RT6 A;  3I04 A;  2GF4 A;  2EX3 B;  4JWC A;  4E3C A;  1DKY A;  4R5G A;  4R5J A;  4R5K A;  3BUB A;  4EZP A;  3LLL A;  3EJS A;  3QWE A;  1TQW A;  4NPH A;  4WPC A;  3A98 A;  2N3K A;  5C5B B;  1UPX A;  2OBM A;  1SU8 A;  4AKV A;  4EZW A;  3T46 A;  3RV0 A;  3T4A G;  4FZS A;  3CV5 A;  4DYL A;  3CKD A;  1YWM A;  4JWE A;  2EFL A;  4AZH A;  3L3P A;  2NCZ A;  3BUD A;  4EZU A;  2QKW A;  4H8S A;  3D50 A;  4FZO A;  4D8J A;  3O3N B;  4HR1 A;  2V0O A;  2EFK A;  2FYV A;  3ACO A;  5TKY A;  3Q84 A;  4IM0 A;  2YLL A;  1SUF A;  2Z8Y A;  4UDY X;  4EZQ A;  3O3M B;  3G9G A;  4JN4 A;  3LVT A;  2YL9 A;  2Z0O A;  4AZI A;  4EZV A;  2LM0 A;  2LXY A;  1WDZ A;  3B51 X;  1E1D A;  4E81 A;  3I01 A;  2RAI A;  2YIV X;  2F1B A;  2F7O A;  2OW7 A;  4EZO A;  1DKZ A;  3LMF A;  3T48 A;  2C08 A;  1R34 A;  3F7W A;  1HWW A;  2F7Q A;  3EJR A;  4AZC A;  3QE6 A;  4BNE A;  3HAJ A;  2F1A A;  4R5L A;  4AZ5 A;  1R5E A;  4JWD A;  1TQV A;  1GNT A;  3EJT A;  2YIA A;  3KAV A;  4UDX X;  3BVW A;  3D4Z A;  4KIK B;  4WPE A;  2ND0 A;  1U00 A;  3B52 X;  3PLT A; 
#chains in the Genus database with same CATH homology
 1Y2O A;  2X3X A;  5C5B B;  2ELB A;  3CAZ A;  3HAI A;  1I4D A;  2Q13 A;  2Q12 A;  2V0O A;  2D1L A;  2RAI A;  4NQI A;  1X03 A;  2X3V A;  1I4T A;  2EFK A;  4AKV A;  3SOG A;  3G9G A;  2YKT A;  3ABH A;  3HAH A;  4ATM A;  3QNI A;  3M3W A;  3ACO A;  4FZS A;  1I49 A;  2RAJ A;  2X3W A;  2C08 A;  2RAK A;  3I2W A;  3OK8 A;  3SYV A;  4DYL A;  2Z0N A;  2Z0O A;  4AVM A;  4DCN C;  3LLL A;  2EFL A;  4NSW A;  4WPE A;  2FIC A;  3Q84 A;  3QWE A;  1URU A;  3QE6 A;  4H8S A;  3DYT A;  4BNE A;  3HAJ A;  3Q0K A;  5C5B A;  4WPC A;  1WDZ A;  1ZWW A;  4I1Q A;  2D4C A;  3PLT A;  1I4L A;  1X04 A;  2Z0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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