2G77A

Crystal structure of gyp1 tbc domain in complex with rab33 gtpase bound to gdp and alf3
Total Genus 135
50100150200250300020406080100120140
Genus TraceResidueGenus

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
388
structure length
331
Chain Sequence
QELNSIIQRISKFDNILKDKTIINQQDLRQISWNGIPKIHRPVVWKLLIGYLPVNTKRQEGFLQRKRKEYRDSLKHTFSDQHSRDIPTWHQIEIDIPRTNPHIPLYQFKSVQNSLQRILYLWAIRHPASGYVQGINDLVTPFFETFLTEYLPPSQIDDVKIKDPSTYMVDEQITDLEADTFWCLTKLLEQITDNYIHGQPGILRQVKNLSQLVKRIDADLYNHFQNEHVEFIQFAFRWMNCLLMREFQMGTVIRMWDTYLSETSQQSSLNEFHVFVCAAFLIKWSDQLMEMDFQETITFLQNPPTKDWTETDIEMLLSEAFIWQSLYKDAT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
AH4 (304-323)EMPTYTIV1 (262-265)TI1 (246-249)AH1 (250-262)AH2 (270-278)TVIII1 (265-268)TI3 (324-327)TI2 (282-285)AH3 (285-294)TVIII2 (298-301)3H1 (301-303)Updating...
connected with : NaN
molecule tags Hydrolase activator/protein transport
source organism Saccharomyces cerevisiae
publication title TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism.
pubmed doi rcsb
molecule keywords GTPase-activating protein GYP1
total genus 135
structure length 331
sequence length 388
ec nomenclature
pdb deposition date 2006-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00566 RabGAP-TBC Rab-GTPase-TBC domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.80 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2g77A02
3QWLA 2QQ8A 2G77A 2QFZA 1FKMA 4HLQA 5EJCA 4Z6YA 3HZJA 3QYBA 3QYEA 4NC6A 4HL4A
chains in the Genus database with same CATH superfamily
2BPMB 4ZGDB 2CYZB 5LMKB 5FGKB 4BCQD 1ENWA 4BCND 3HZJA 4NC6A 3EJ1B 4KRCB 4QSHA 1OKWB 2C5NB 3BG3A 1PKDB 2C5XB 4EC8B 4BCMD 1QMZB 4ELJA 1H1SB 1UNGD 5HQ0B 2IW9B 5HBHB 4BCHB 4BBSM 1N4MA 4BCNB 5DQVA 4AKHA 2ZPGB 4EC9B 4Y72B 4TTHA 2CCIB 4CFWB 4F7NB 4BCIB 1GUXA 2I53A 2W9ZA 4ZGJB 1C9BA 4MFEA 3BLRB 2CZ7B 2IN3A 2PK9B 3X25B 1UNLD 2BKZB 2WPAB 1H24B 1URCB 4JX6A 1OKVB 4EOQB 1W98B 5ICPB 3TNHB 2CZ1B 1AHJB 2WEVB 1JKWA 1V29B 3RGFB 4CFUD 1O9KA 3O0GD 1JSTB 1UGRB 4HNTA 3VKHA 1E9HB 2W96A 3DTOA 4AKIA 4HNUA 1GUXB 4F70B 1GY3B 4HNVA 2KMGA 2IW6B 2PMIB 1OI9B 5IDPB 3DDQB 4F7LB 2IVXA 3BLQB 4FX3B 4G6LB 3X20B 4BCJB 5HBEB 3BHVB 2BS2A 2DPPB 5ACBA 1JSUB 3DOGB 1H1QB 4OGRB 1H1RB 1H28B 3VKGA 1G3NC 2X1NB 2BS3A 3F5XB 2QDYB 4BCPB 3TNIB 2ZPFB 5HNBB 1AD6A 2W2HA 4BCGB 4YOSA 1O9KB 4I3ZB 1KXUA 1H25B 1OIYB 2PHGA 3QHRB 4CRLB 4BCFB 1IREB 2BS4A 2JGZB 2DXBB 3K7AM 4AI6A 4CXAB 3DJBA 3QHWB 1H4LD 2V22B 1UGSB 5EFQB 4YC3B 5IHYA 3X26B 4BCOB 5BNJB 3MI9B 4ROEA 5IDNB 3DL1A 2C6TB 3VYGB 1FINB 4OB3B 3A8HB 2WIHB 3HHTB 4ZGEB 2DD5B 1H27B 2AHJB 3WVEB 4BY1X 4MFDA 2C5VB 2C5OB 2PJQA 5DQWA 2G9XB 2WFYB 2W99A 1BU2A 1GH6B 1F5QB 4EOOB 2DMEA 1P5EB 3MY1B 2DD4B 5CYIB 4BY7X 3X24B 3KHIA 4LOCA 4F7JB 3QZ9B 2ZZDB 4HL4A 5EJCA 1H26B 3QYEA 3EIDB 4BXXX 3BG9A 2D0QB 4ROCA 2CJMB 3HBLA 2CZ0B 2LW4A 1JOWA 4EOMB 4JX5A 4MIMA 2UZDB 3TW6A 1E7PA 3TNWB 2CZ6B 1VOLA 4KRDB 4UN0A 3QWLA 4EORB 2CCHB 3HO8A 3PO3S 4M6VA 4EOPB 1UNHD 2WMAB 4F6WB 2ZPIB 4EOIB 2B9RA 2QF7A 2QFZA 3POMA 2DXCB 2QGSA 5L2WB 4RODA 4OB0B 3BLHB 1OL2B 2UUEB 3A8GB 3DDPB 3NDQA 3QYBA 3VYHB 2QDJA 4ELLA 3BHUB 5HBJB 3B57A 4JX4A 1OIUB 2C4GB 4EOKB 3A8LB 4EOJB 2WHBB 3MY5B 2WIPB 1H1PB 1OGUB 2WJ9A 1VINA 4BCQB 3G33B 1OL1B 3BG5A 4OB1B 5CEIB 3A8MB 4YOOA 4BBRM 4F7SB 3QYGB 4BCMB 4Z6YA 2IW8B 4CFVB 3H4CA 3A8OB 4EOSB 2ZPEB 4IMYB 3HB9A 3QXEB 4EOLB 5I5ZB 2UZLB 4FM4B 4CFMB 4OB2B 2UZEB 1AISB 1ZP2A 3EOCB 4OR5B 2ZCFB 5HVYB 2I40B 3QYHB 2PK2A 4HLQA 2ZPHB 1FVVB 1VYWB 1TD6A 4CFXB 2EUFA 1QLBA 3TN8B 2G77A 4CFNB 4BCKB 3QZ5B 4F6SB 3MIAB 5IF1B 4NSTB 4II5B 2ZPBB 3WVDB 4EONB 3LQ5B 1TFBA 3TW7A 2R7GA 1XO2A 4F6UB 2W9FA 3X28B 5LQFB 4CFUB 1UGPB 2F2CA 1UGQB 4AKGA 3BHTB 2UZBB 3GTMS 2WMBB 1D3UB 2KR6A 3M03A 2QQ8A 4YOZA 1FKMA 2WXVB
chains in the Genus database with same CATH topology
4ZGDB 2CYZB 3BG5A 4OB1B 4AKIA 4HNUA 4HNVA 3A8MB 2KMGA 4BBRM 3HZJA 4NC6A 3QYGB 4QSHA 3X20B 4Z6YA 3BG3A 2DD4B 3X24B 3KHIA 4ELJA 2BS2A 4LOCA 2DPPB 3QZ9B 2ZZDB 4HL4A 5EJCA 3H4CA 3A8OB 2ZPEB 4BBSM 3QYEA 3HB9A 3QXEB 4FM4B 4OB2B 4AKHA 3BG9A 3VKGA 2ZPGB 2D0QB 2BS3A 2QDYB 2ZCFB 2CZ0B 3HBLA 4ZGJB 3QYHB 4MFEA 2ZPFB 4JX5A 4MIMA 3TW6A 2CZ7B 4HLQA 1E7PA 2ZPHB 2CZ6B 1QLBA 3QWLA 2G77A 3HO8A 3QZ5B 1IREB 2BS4A 4M6VA 3X25B 2DXBB 2ZPIB 4AI6A 2QF7A 2QFZA 2ZPBB 4JX6A 1UGSB 3WVDB 2DXCB 3TW7A 4OB0B 3X26B 3A8GB 3X28B 2CZ1B 3QYBA 3VYHB 2QDJA 1AHJB 1UGPB 3DL1A 1UGQB 4JX4A 4AKGA 1V29B 3VYGB 3A8LB 4OB3B 1UGRB 4HNTA 3A8HB 3VKHA 3HHTB 4ZGEB 2KR6A 2DD5B 2AHJB 2QQ8A 1FKMA 2WJ9A 3WVEB 4MFDA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3QWL A;  2QQ8 A;  2G77 A;  2QFZ A;  1FKM A;  4HLQ A;  5EJC A;  4Z6Y A;  3HZJ A;  3QYB A;  3QYE A;  4NC6 A;  4HL4 A; 
#chains in the Genus database with same CATH topology
 2BPM B;  4ZGD B;  2CYZ B;  5LMK B;  5FGK B;  4BCQ D;  1ENW A;  4BCN D;  3HZJ A;  4NC6 A;  3EJ1 B;  4KRC B;  4QSH A;  1OKW B;  2C5N B;  3BG3 A;  1PKD B;  2C5X B;  4EC8 B;  4BCM D;  1QMZ B;  4ELJ A;  1H1S B;  1UNG D;  5HQ0 B;  2IW9 B;  5HBH B;  4BCH B;  4BBS M;  1N4M A;  4BCN B;  5DQV A;  4AKH A;  2ZPG B;  4EC9 B;  4Y72 B;  4TTH A;  2CCI B;  4CFW B;  4F7N B;  4BCI B;  1GUX A;  2I53 A;  2W9Z A;  4ZGJ B;  1C9B A;  4MFE A;  3BLR B;  2CZ7 B;  2IN3 A;  2PK9 B;  3X25 B;  1UNL D;  2BKZ B;  2WPA B;  1H24 B;  1URC B;  4JX6 A;  1OKV B;  4EOQ B;  1W98 B;  5ICP B;  3TNH B;  2CZ1 B;  1AHJ B;  2WEV B;  1JKW A;  1V29 B;  3RGF B;  4CFU D;  1O9K A;  3O0G D;  1JST B;  1UGR B;  4HNT A;  3VKH A;  1E9H B;  2W96 A;  3DTO A;  4AKI A;  4HNU A;  1GUX B;  4F70 B;  1GY3 B;  4HNV A;  2KMG A;  2IW6 B;  2PMI B;  1OI9 B;  5IDP B;  3DDQ B;  4F7L B;  2IVX A;  3BLQ B;  4FX3 B;  4G6L B;  3X20 B;  4BCJ B;  5HBE B;  3BHV B;  2BS2 A;  2DPP B;  5ACB A;  1JSU B;  3DOG B;  1H1Q B;  4OGR B;  1H1R B;  1H28 B;  3VKG A;  1G3N C;  2X1N B;  2BS3 A;  3F5X B;  2QDY B;  4BCP B;  3TNI B;  2ZPF B;  5HNB B;  1AD6 A;  2W2H A;  4BCG B;  4YOS A;  1O9K B;  4I3Z B;  1KXU A;  1H25 B;  1OIY B;  2PHG A;  3QHR B;  4CRL B;  4BCF B;  1IRE B;  2BS4 A;  2JGZ B;  2DXB B;  3K7A M;  4AI6 A;  4CXA B;  3DJB A;  3QHW B;  1H4L D;  2V22 B;  1UGS B;  5EFQ B;  4YC3 B;  5IHY A;  3X26 B;  4BCO B;  5BNJ B;  3MI9 B;  4ROE A;  5IDN B;  3DL1 A;  2C6T B;  3VYG B;  1FIN B;  4OB3 B;  3A8H B;  2WIH B;  3HHT B;  4ZGE B;  2DD5 B;  1H27 B;  2AHJ B;  3WVE B;  4BY1 X;  4MFD A;  2C5V B;  2C5O B;  2PJQ A;  5DQW A;  2G9X B;  2WFY B;  2W99 A;  1BU2 A;  1GH6 B;  1F5Q B;  4EOO B;  2DME A;  1P5E B;  3MY1 B;  2DD4 B;  5CYI B;  4BY7 X;  3X24 B;  3KHI A;  4LOC A;  4F7J B;  3QZ9 B;  2ZZD B;  4HL4 A;  5EJC A;  1H26 B;  3QYE A;  3EID B;  4BXX X;  3BG9 A;  2D0Q B;  4ROC A;  2CJM B;  3HBL A;  2CZ0 B;  2LW4 A;  1JOW A;  4EOM B;  4JX5 A;  4MIM A;  2UZD B;  3TW6 A;  1E7P A;  3TNW B;  2CZ6 B;  1VOL A;  4KRD B;  4UN0 A;  3QWL A;  4EOR B;  2CCH B;  3HO8 A;  3PO3 S;  4M6V A;  4EOP B;  1UNH D;  2WMA B;  4F6W B;  2ZPI B;  4EOI B;  2B9R A;  2QF7 A;  2QFZ A;  3POM A;  2DXC B;  2QGS A;  5L2W B;  4ROD A;  4OB0 B;  3BLH B;  1OL2 B;  2UUE B;  3A8G B;  3DDP B;  3NDQ A;  3QYB A;  3VYH B;  2QDJ A;  4ELL A;  3BHU B;  5HBJ B;  3B57 A;  4JX4 A;  1OIU B;  2C4G B;  4EOK B;  3A8L B;  4EOJ B;  2WHB B;  3MY5 B;  2WIP B;  1H1P B;  1OGU B;  2WJ9 A;  1VIN A;  4BCQ B;  3G33 B;  1OL1 B;  3BG5 A;  4OB1 B;  5CEI B;  3A8M B;  4YOO A;  4BBR M;  4F7S B;  3QYG B;  4BCM B;  4Z6Y A;  2IW8 B;  4CFV B;  3H4C A;  3A8O B;  4EOS B;  2ZPE B;  4IMY B;  3HB9 A;  3QXE B;  4EOL B;  5I5Z B;  2UZL B;  4FM4 B;  4CFM B;  4OB2 B;  2UZE B;  1AIS B;  1ZP2 A;  3EOC B;  4OR5 B;  2ZCF B;  5HVY B;  2I40 B;  3QYH B;  2PK2 A;  4HLQ A;  2ZPH B;  1FVV B;  1VYW B;  1TD6 A;  4CFX B;  2EUF A;  1QLB A;  3TN8 B;  2G77 A;  4CFN B;  4BCK B;  3QZ5 B;  4F6S B;  3MIA B;  5IF1 B;  4NST B;  4II5 B;  2ZPB B;  3WVD B;  4EON B;  3LQ5 B;  1TFB A;  3TW7 A;  2R7G A;  1XO2 A;  4F6U B;  2W9F A;  3X28 B;  5LQF B;  4CFU B;  1UGP B;  2F2C A;  1UGQ B;  4AKG A;  3BHT B;  2UZB B;  3GTM S;  2WMB B;  1D3U B;  2KR6 A;  3M03 A;  2QQ8 A;  4YOZ A;  1FKM A;  2WXV B; 
#chains in the Genus database with same CATH homology
 4ZGD B;  2CYZ B;  3BG5 A;  4OB1 B;  4AKI A;  4HNU A;  4HNV A;  3A8M B;  2KMG A;  4BBR M;  3HZJ A;  4NC6 A;  3QYG B;  4QSH A;  3X20 B;  4Z6Y A;  3BG3 A;  2DD4 B;  3X24 B;  3KHI A;  4ELJ A;  2BS2 A;  4LOC A;  2DPP B;  3QZ9 B;  2ZZD B;  4HL4 A;  5EJC A;  3H4C A;  3A8O B;  2ZPE B;  4BBS M;  3QYE A;  3HB9 A;  3QXE B;  4FM4 B;  4OB2 B;  4AKH A;  3BG9 A;  3VKG A;  2ZPG B;  2D0Q B;  2BS3 A;  2QDY B;  2ZCF B;  2CZ0 B;  3HBL A;  4ZGJ B;  3QYH B;  4MFE A;  2ZPF B;  4JX5 A;  4MIM A;  3TW6 A;  2CZ7 B;  4HLQ A;  1E7P A;  2ZPH B;  2CZ6 B;  1QLB A;  3QWL A;  2G77 A;  3HO8 A;  3QZ5 B;  1IRE B;  2BS4 A;  4M6V A;  3X25 B;  2DXB B;  2ZPI B;  4AI6 A;  2QF7 A;  2QFZ A;  2ZPB B;  4JX6 A;  1UGS B;  3WVD B;  2DXC B;  3TW7 A;  4OB0 B;  3X26 B;  3A8G B;  3X28 B;  2CZ1 B;  3QYB A;  3VYH B;  2QDJ A;  1AHJ B;  1UGP B;  3DL1 A;  1UGQ B;  4JX4 A;  4AKG A;  1V29 B;  3VYG B;  3A8L B;  4OB3 B;  1UGR B;  4HNT A;  3A8H B;  3VKH A;  3HHT B;  4ZGE B;  2KR6 A;  2DD5 B;  2AHJ B;  2QQ8 A;  1FKM A;  2WJ9 A;  3WVE B;  4MFD A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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