2KMGA

The structure of the klca and ardb proteins show a novel fold and antirestriction activity against type i dna restriction systems in vivo but not in vitro
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
142
structure length
142
Chain Sequence
MNTEEQPVTASLVAEAQRLDFLPTYFGPRLMMRGEALVYAWMRRLCERYNGAYWHYYALSDGGFYMAPDLAGRLEIEVNGNGFRGELSADAAGIVATLFALGQLAAEIADTDAADALIDRYHFLRGFAAGHPEAAAIYRAID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Gene regulation
source organism Bordetella pertussis
publication title The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro
pubmed doi rcsb
molecule keywords KlcA
total genus 31
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2009-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03230 Antirestrict Antirestriction protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.120 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2kmgA00
2KMGA 2WJ9A
chains in the Genus database with same CATH superfamily
3VYHB 2C4GB 4ZGJB 1O9KA 4BCKB 3HHTB 5FGKB 1ENWA 1H1PB 4F7JB 2BS3A 2PMIB 3X24B 4JX4A 4CFVB 2CZ7B 2UZBB 4BCMD 1GY3B 4IMYB 5CEIB 1FINB 4BY1X 3B57A 1E7PA 4KRDB 1JOWA 3TNWB 5EFQB 2JGZB 2DD4B 4CFXB 2WEVB 3X20B 4BCND 2UZLB 3BLHB 4EOQB 3DDQB 3F5XB 3A8OB 1P5EB 4UN0A 3TNIB 4BY7X 2IVXA 2QGSA 2X1NB 1D3UB 1UGSB 4BCJB 1FKMA 3RGFB 2BKZB 3QYEA 4EOMB 4CFWB 4EOPB 4I3ZB 4CFNB 3QXEB 5HBHB 2G9XB 1OKWB 2CZ6B 3DOGB 3H4CA 1VOLA 2WIPB 1OI9B 2CJMB 5IDPB 3WVEB 1V29B 3A8LB 4BCHB 2ZPGB 3DTOA 5IF1B 1JSTB 4BCFB 4CFMB 3BG5A 2KMGA 1TFBA 4II5B 1H24B 2UZEB 2IW6B 1O9KB 4EOJB 3VKHA 2DD5B 1AD6A 1H4LD 2G77A 1F5QB 4YOZA 4EOKB 3TNHB 2CZ1B 2BS4A 3MY1B 2W9FA 4HL4A 4BXXX 1H1QB 4MFDA 4HNTA 1FVVB 1H26B 1E9HB 2I40B 4BBSM 4BCQB 2QQ8A 1H25B 4OB2B 2ZPBB 4HLQA 1H1SB 3EJ1B 3BHVB 5L2WB 3EOCB 2DMEA 3LQ5B 4AKGA 1OGUB 3HB9A 3QHRB 1W98B 4NC6A 4EOSB 4BCPB 2C5NB 2PK9B 3QZ9B 5HVYB 5ACBA 2W96A 1OL1B 5CYIB 5IHYA 1OL2B 3BLQB 2C6TB 5DQWA 4YOSA 3BHUB 4YC3B 4MIMA 1OKVB 2QFZA 4CFUB 4G6LB 4NSTB 4EOOB 1JSUB 3DJBA 1KXUA 3BLRB 3TW7A 3HBLA 1GUXB 4BCGB 4ELJA 3A8GB 1QLBA 4ROEA 3GTMS 5ICPB 4EC8B 4ZGEB 3BG3A 4Z6YA 3QHWB 2ZCFB 2IN3A 2ZZDB 4OB0B 4Y72B 3X26B 2CYZB 5HBEB 4CRLB 2KR6A 4RODA 1OIUB 4JX6A 2WJ9A 1XO2A 3HO8A 4MFEA 4HNVA 3G33B 3TW6A 2ZPFB 3M03A 2C5XB 1QMZB 5LMKB 3TN8B 1H28B 1UGPB 4BCMB 1UGRB 5IDNB 2W9ZA 1BU2A 2QDYB 2WIHB 5EJCA 4AKHA 4F7NB 2ZPHB 4YOOA 1C9BA 4OGRB 4F6WB 4BCNB 2UZDB 2ZPEB 3X28B 3QWLA 1G3NC 1N4MA 1OIYB 4OR5B 4F70B 2QDJA 1VYWB 2WXVB 4F7LB 2QF7A 3HZJA 1UNLD 1VINA 5I5ZB 3K7AM 4F6SB 2PJQA 1ZP2A 1JKWA 2EUFA 3VYGB 2CCIB 3MY5B 4EOIB 2DXCB 3A8HB 1PKDB 2IW8B 3EIDB 2WMAB 1URCB 2ZPIB 5HQ0B 4FM4B 2R7GA 2CCHB 3MI9B 4EONB 1IREB 2PK2A 4BCQD 4TTHA 2C5VB 4CXAB 1AHJB 3POMA 2BPMB 3QYHB 3QZ5B 1UGQB 2IW9B 4F6UB 5DQVA 1H1RB 3PO3S 4FX3B 2WMBB 4ELLA 3BG9A 3MIAB 4EORB 2F2CA 2D0QB 3O0GD 4LOCA 2W99A 1H27B 1UNHD 2W2HA 3QYBA 3WVDB 2UUEB 3A8MB 1GH6B 2PHGA 2WFYB 4OB1B 2C5OB 3DL1A 4EOLB 4KRCB 4JX5A 4ZGDB 4BBRM 2DXBB 1GUXA 4CFUD 2V22B 2I53A 4HNUA 3QYGB 4F7SB 2AHJB 1UNGD 5HBJB 3NDQA 3X25B 3VKGA 2B9RA 3BHTB 5LQFB 2DPPB 2BS2A 4OB3B 2LW4A 2WPAB 4M6VA 4BCOB 4AKIA 5BNJB 3DDPB 1AISB 5HNBB 1TD6A 4ROCA 3KHIA 4BCIB 4EC9B 4AI6A 4QSHA 2WHBB 2CZ0B
chains in the Genus database with same CATH topology
4OB0B 3VKHA 2DD5B 3VYHB 2G77A 3X26B 2CYZB 4ZGJB 3HHTB 2KR6A 1IREB 4JX6A 2CZ1B 2WJ9A 2BS3A 3HO8A 3X24B 2BS4A 4JX4A 4MFEA 4HL4A 2CZ7B 4HNVA 1AHJB 4MFDA 4HNTA 3TW6A 3QYHB 3QZ5B 2ZPFB 4BBSM 1UGQB 2QQ8A 1E7PA 4OB2B 2ZPBB 1UGPB 4HLQA 1UGRB 3BG9A 2DD4B 3X20B 2D0QB 4AKGA 2QDYB 3HB9A 5EJCA 4AKHA 3A8OB 4LOCA 2ZPHB 3QYBA 4NC6A 3WVDB 3A8MB 3QZ9B 2ZPEB 4OB1B 3DL1A 1UGSB 3X28B 1FKMA 3QWLA 4JX5A 2CZ0B 3QYEA 4ZGDB 4BBRM 2DXBB 2QDJA 3QXEB 4HNUA 3QYGB 2AHJB 2CZ6B 2QF7A 3H4CA 3HZJA 4MIMA 3X25B 2QFZA 3VKGA 3WVEB 1V29B 3A8LB 2DPPB 3TW7A 2BS2A 3VYGB 3HBLA 4OB3B 2ZPGB 4M6VA 4ELJA 2DXCB 3A8GB 4AKIA 1QLBA 3BG5A 3A8HB 4ZGEB 3BG3A 4Z6YA 3KHIA 2KMGA 2ZPIB 4AI6A 4FM4B 4QSHA 2ZCFB 2ZZDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KMG A;  2WJ9 A; 
#chains in the Genus database with same CATH topology
 3VYH B;  2C4G B;  4ZGJ B;  1O9K A;  4BCK B;  3HHT B;  5FGK B;  1ENW A;  1H1P B;  4F7J B;  2BS3 A;  2PMI B;  3X24 B;  4JX4 A;  4CFV B;  2CZ7 B;  2UZB B;  4BCM D;  1GY3 B;  4IMY B;  5CEI B;  1FIN B;  4BY1 X;  3B57 A;  1E7P A;  4KRD B;  1JOW A;  3TNW B;  5EFQ B;  2JGZ B;  2DD4 B;  4CFX B;  2WEV B;  3X20 B;  4BCN D;  2UZL B;  3BLH B;  4EOQ B;  3DDQ B;  3F5X B;  3A8O B;  1P5E B;  4UN0 A;  3TNI B;  4BY7 X;  2IVX A;  2QGS A;  2X1N B;  1D3U B;  1UGS B;  4BCJ B;  1FKM A;  3RGF B;  2BKZ B;  3QYE A;  4EOM B;  4CFW B;  4EOP B;  4I3Z B;  4CFN B;  3QXE B;  5HBH B;  2G9X B;  1OKW B;  2CZ6 B;  3DOG B;  3H4C A;  1VOL A;  2WIP B;  1OI9 B;  2CJM B;  5IDP B;  3WVE B;  1V29 B;  3A8L B;  4BCH B;  2ZPG B;  3DTO A;  5IF1 B;  1JST B;  4BCF B;  4CFM B;  3BG5 A;  2KMG A;  1TFB A;  4II5 B;  1H24 B;  2UZE B;  2IW6 B;  1O9K B;  4EOJ B;  3VKH A;  2DD5 B;  1AD6 A;  1H4L D;  2G77 A;  1F5Q B;  4YOZ A;  4EOK B;  3TNH B;  2CZ1 B;  2BS4 A;  3MY1 B;  2W9F A;  4HL4 A;  4BXX X;  1H1Q B;  4MFD A;  4HNT A;  1FVV B;  1H26 B;  1E9H B;  2I40 B;  4BBS M;  4BCQ B;  2QQ8 A;  1H25 B;  4OB2 B;  2ZPB B;  4HLQ A;  1H1S B;  3EJ1 B;  3BHV B;  5L2W B;  3EOC B;  2DME A;  3LQ5 B;  4AKG A;  1OGU B;  3HB9 A;  3QHR B;  1W98 B;  4NC6 A;  4EOS B;  4BCP B;  2C5N B;  2PK9 B;  3QZ9 B;  5HVY B;  5ACB A;  2W96 A;  1OL1 B;  5CYI B;  5IHY A;  1OL2 B;  3BLQ B;  2C6T B;  5DQW A;  4YOS A;  3BHU B;  4YC3 B;  4MIM A;  1OKV B;  2QFZ A;  4CFU B;  4G6L B;  4NST B;  4EOO B;  1JSU B;  3DJB A;  1KXU A;  3BLR B;  3TW7 A;  3HBL A;  1GUX B;  4BCG B;  4ELJ A;  3A8G B;  1QLB A;  4ROE A;  3GTM S;  5ICP B;  4EC8 B;  4ZGE B;  3BG3 A;  4Z6Y A;  3QHW B;  2ZCF B;  2IN3 A;  2ZZD B;  4OB0 B;  4Y72 B;  3X26 B;  2CYZ B;  5HBE B;  4CRL B;  2KR6 A;  4ROD A;  1OIU B;  4JX6 A;  2WJ9 A;  1XO2 A;  3HO8 A;  4MFE A;  4HNV A;  3G33 B;  3TW6 A;  2ZPF B;  3M03 A;  2C5X B;  1QMZ B;  5LMK B;  3TN8 B;  1H28 B;  1UGP B;  4BCM B;  1UGR B;  5IDN B;  2W9Z A;  1BU2 A;  2QDY B;  2WIH B;  5EJC A;  4AKH A;  4F7N B;  2ZPH B;  4YOO A;  1C9B A;  4OGR B;  4F6W B;  4BCN B;  2UZD B;  2ZPE B;  3X28 B;  3QWL A;  1G3N C;  1N4M A;  1OIY B;  4OR5 B;  4F70 B;  2QDJ A;  1VYW B;  2WXV B;  4F7L B;  2QF7 A;  3HZJ A;  1UNL D;  1VIN A;  5I5Z B;  3K7A M;  4F6S B;  2PJQ A;  1ZP2 A;  1JKW A;  2EUF A;  3VYG B;  2CCI B;  3MY5 B;  4EOI B;  2DXC B;  3A8H B;  1PKD B;  2IW8 B;  3EID B;  2WMA B;  1URC B;  2ZPI B;  5HQ0 B;  4FM4 B;  2R7G A;  2CCH B;  3MI9 B;  4EON B;  1IRE B;  2PK2 A;  4BCQ D;  4TTH A;  2C5V B;  4CXA B;  1AHJ B;  3POM A;  2BPM B;  3QYH B;  3QZ5 B;  1UGQ B;  2IW9 B;  4F6U B;  5DQV A;  1H1R B;  3PO3 S;  4FX3 B;  2WMB B;  4ELL A;  3BG9 A;  3MIA B;  4EOR B;  2F2C A;  2D0Q B;  3O0G D;  4LOC A;  2W99 A;  1H27 B;  1UNH D;  2W2H A;  3QYB A;  3WVD B;  2UUE B;  3A8M B;  1GH6 B;  2PHG A;  2WFY B;  4OB1 B;  2C5O B;  3DL1 A;  4EOL B;  4KRC B;  4JX5 A;  4ZGD B;  4BBR M;  2DXB B;  1GUX A;  4CFU D;  2V22 B;  2I53 A;  4HNU A;  3QYG B;  4F7S B;  2AHJ B;  1UNG D;  5HBJ B;  3NDQ A;  3X25 B;  3VKG A;  2B9R A;  3BHT B;  5LQF B;  2DPP B;  2BS2 A;  4OB3 B;  2LW4 A;  2WPA B;  4M6V A;  4BCO B;  4AKI A;  5BNJ B;  3DDP B;  1AIS B;  5HNB B;  1TD6 A;  4ROC A;  3KHI A;  4BCI B;  4EC9 B;  4AI6 A;  4QSH A;  2WHB B;  2CZ0 B; 
#chains in the Genus database with same CATH homology
 4OB0 B;  3VKH A;  2DD5 B;  3VYH B;  2G77 A;  3X26 B;  2CYZ B;  4ZGJ B;  3HHT B;  2KR6 A;  1IRE B;  4JX6 A;  2CZ1 B;  2WJ9 A;  2BS3 A;  3HO8 A;  3X24 B;  2BS4 A;  4JX4 A;  4MFE A;  4HL4 A;  2CZ7 B;  4HNV A;  1AHJ B;  4MFD A;  4HNT A;  3TW6 A;  3QYH B;  3QZ5 B;  2ZPF B;  4BBS M;  1UGQ B;  2QQ8 A;  1E7P A;  4OB2 B;  2ZPB B;  1UGP B;  4HLQ A;  1UGR B;  3BG9 A;  2DD4 B;  3X20 B;  2D0Q B;  4AKG A;  2QDY B;  3HB9 A;  5EJC A;  4AKH A;  3A8O B;  4LOC A;  2ZPH B;  3QYB A;  4NC6 A;  3WVD B;  3A8M B;  3QZ9 B;  2ZPE B;  4OB1 B;  3DL1 A;  1UGS B;  3X28 B;  1FKM A;  3QWL A;  4JX5 A;  2CZ0 B;  3QYE A;  4ZGD B;  4BBR M;  2DXB B;  2QDJ A;  3QXE B;  4HNU A;  3QYG B;  2AHJ B;  2CZ6 B;  2QF7 A;  3H4C A;  3HZJ A;  4MIM A;  3X25 B;  2QFZ A;  3VKG A;  3WVE B;  1V29 B;  3A8L B;  2DPP B;  3TW7 A;  2BS2 A;  3VYG B;  3HBL A;  4OB3 B;  2ZPG B;  4M6V A;  4ELJ A;  2DXC B;  3A8G B;  4AKI A;  1QLB A;  3BG5 A;  3A8H B;  4ZGE B;  3BG3 A;  4Z6Y A;  3KHI A;  2KMG A;  2ZPI B;  4AI6 A;  4FM4 B;  4QSH A;  2ZCF B;  2ZZD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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