2KMGA

The structure of the klca and ardb proteins show a novel fold and antirestriction activity against type i dna restriction systems in vivo but not in vitro
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
142
structure length
142
Chain Sequence
MNTEEQPVTASLVAEAQRLDFLPTYFGPRLMMRGEALVYAWMRRLCERYNGAYWHYYALSDGGFYMAPDLAGRLEIEVNGNGFRGELSADAAGIVATLFALGQLAAEIADTDAADALIDRYHFLRGFAAGHPEAAAIYRAID
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro
pubmed doi rcsb
molecule tags Gene regulation
source organism Bordetella pertussis
molecule keywords KlcA
total genus 31
structure length 142
sequence length 142
ec nomenclature
pdb deposition date 2009-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03230 Antirestrict Antirestriction protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.120 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2kmgA00
2KMGA 2WJ9A
chains in the Genus database with same CATH superfamily
4YOSA 4II5B 1OI9B 1UNGD 1KXUA 1FVVB 2CZ6B 3QYBA 3EOCB 4KRCB 3X28B 4CXAB 1H27B 4BCNB 1UGQB 3DJBA 4AI6A 2BPMB 3QZ9B 3NDQA 1VINA 3EJ1B 4TTHA 1H26B 2W9ZA 3DL1A 2ZPFB 5L2WB 1D3UB 3BLQB 1UNHD 2UUEB 3VKHA 4CFMB 4BCGB 3HB9A 2BS2A 2PJQA 4ZGEB 4M6VA 5FGKB 2QQ8A 2JGZB 1N4MA 4OB0B 2WHBB 4FM4B 2QGSA 4EC9B 4BCPB 3BLHB 4CFUB 1AISB 3DDQB 4BCJB 4YC3B 4G6LB 2CYZB 4BCQB 2DXBB 4CRLB 2ZCFB 5IF1B 2DPPB 2D0QB 5HNBB 4KRDB 1JKWA 2R7GA 2C5XB 4CFVB 1OL1B 4OB1B 5IHYA 2BS3A 1PKDB 4EORB 4F7LB 3KHIA 1VOLA 5BNJB 1E7PA 1GUXB 2DD4B 5EJCA 2X1NB 2WEVB 2AHJB 5IDPB 4BY7X 1E9HB 1G3NC 2C5NB 1O9KB 4BCIB 2C5OB 4BCMB 1OL2B 2WXVB 3BLRB 4ROEA 1QLBA 2C5VB 2QF7A 3RGFB 3HZJA 2WJ9A 4HNTA 1VYWB 4EOOB 1TFBA 4IMYB 3QHWB 4HNVA 3VYGB 5DQVA 5HBJB 1UNLD 3HHTB 2WIHB 3QYGB 2BS4A 2UZEB 2WPAB 4OB3B 2DMEA 5HVYB 4JX5A 2C6TB 3A8HB 2W96A 3QWLA 4EOKB 2IW8B 2CCIB 1OKVB 4EOSB 1UGPB 3BG9A 2QFZA 3H4CA 1ZP2A 2PMIB 1W98B 2PK9B 4EOPB 4EOQB 4YOOA 2B9RA 1XO2A 4YOZA 4F70B 1GUXA 1H1QB 5CYIB 4NSTB 3EIDB 1JSUB 4LOCA 1H4LD 3BG5A 2W9FA 3POMA 3X24B 1V29B 2ZPGB 4RODA 4BCKB 4BCND 2UZBB 2BKZB 2PHGA 1ENWA 4MIMA 3WVDB 1O9KA 2QDJA 2I53A 1AD6A 4MFDA 4AKGA 4HLQA 4NC6A 2IVXA 5HQ0B 3DOGB 2WFYB 1OGUB 4ELJA 3HO8A 3PO3S 2CJMB 4UN0A 2WMAB 1QMZB 3QYEA 4I3ZB 4EOIB 5HBHB 4JX6A 4MFEA 3HBLA 1TD6A 2UZDB 2CCHB 3TW7A 2F2CA 3BHVB 1GY3B 1H25B 4EOMB 3TN8B 4BCHB 3BHUB 4F6SB 3F5XB 3LQ5B 3VKGA 3MY1B 1OIUB 5ACBA 4ROCA 4Y72B 4BCQD 4F7SB 1P5EB 2KR6A 1UGRB 4F6UB 4ZGDB 4BBSM 2W2HA 3VYHB 2ZPBB 5HBEB 3BG3A 2DD5B 2IW9B 4QSHA 1URCB 2LW4A 3B57A 2CZ1B 3MY5B 4BBRM 1H28B 3TNWB 5LMKB 3X25B 2ZZDB 5ICPB 3DTOA 3TNHB 3TNIB 2IW6B 4FX3B 2G77A 5IDNB 2C4GB 4CFXB 4BXXX 2UZLB 3QZ5B 3M03A 1H1SB 4ELLA 4AKHA 3X26B 3MI9B 4BCMD 1GH6B 4CFWB 4OR5B 4CFNB 4OB2B 4OGRB 3G33B 4EC8B 2EUFA 2W99A 1IREB 3O0GD 5CEIB 3TW6A 3A8MB 5EFQB 1H1PB 3K7AM 4F6WB 3WVEB 2ZPIB 1F5QB 4ZGJB 3GTMS 3QYHB 1H24B 1FKMA 4F7JB 1FINB 1C9BA 3A8LB 1BU2A 3MIAB 4EOJB 3DDPB 5I5ZB 2I40B 1H1RB 4Z6YA 1OKWB 4HNUA 2PK2A 4AKIA 2ZPHB 2DXCB 1JOWA 4BY1X 4BCFB 4EONB 4CFUD 5DQWA 4BCOB 2CZ0B 3QXEB 3BHTB 2IN3A 3X20B 1OIYB 2QDYB 2WIPB 2V22B 1JSTB 3QHRB 3A8GB 2WMBB 1UGSB 4HL4A 4EOLB 2G9XB 2KMGA 1AHJB 4JX4A 5LQFB 2CZ7B 2ZPEB 3A8OB 4F7NB
chains in the Genus database with same CATH topology
2AHJB 4OB2B 3WVDB 2QDJA 4MFDA 4AKGA 4HLQA 4NC6A 2CZ6B 3QYBA 3X28B 4ELJA 3HO8A 1IREB 3TW6A 3A8MB 1UGQB 4AI6A 3QYEA 3QZ9B 1QLBA 2QF7A 4JX6A 4MFEA 3HZJA 3HBLA 3WVEB 2ZPIB 2WJ9A 4ZGJB 4HNTA 3QYHB 1FKMA 3DL1A 3TW7A 2ZPFB 4HNVA 3VYGB 3A8LB 3VKHA 3HB9A 2BS2A 3HHTB 4ZGEB 4M6VA 3QYGB 3VKGA 2BS4A 2QQ8A 4OB3B 4OB0B 4FM4B 4Z6YA 4HNUA 2KR6A 4JX5A 1UGRB 3A8HB 4AKIA 4ZGDB 4BBSM 3QWLA 3VYHB 2ZPBB 2ZPHB 2DXCB 3BG3A 2DD5B 4QSHA 1UGPB 3BG9A 2QFZA 3H4CA 2CZ1B 4BBRM 2CYZB 2DXBB 3X25B 2ZZDB 2ZCFB 2CZ0B 2DPPB 2D0QB 3QXEB 2G77A 3X20B 2QDYB 4OB1B 2BS3A 4LOCA 3A8GB 3BG5A 3QZ5B 3X24B 1V29B 1UGSB 3KHIA 2ZPGB 4HL4A 1E7PA 2DD4B 5EJCA 4AKHA 2KMGA 3X26B 1AHJB 4JX4A 2CZ7B 2ZPEB 3A8OB 4MIMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KMG A;  2WJ9 A; 
#chains in the Genus database with same CATH topology
 4YOS A;  4II5 B;  1OI9 B;  1UNG D;  1KXU A;  1FVV B;  2CZ6 B;  3QYB A;  3EOC B;  4KRC B;  3X28 B;  4CXA B;  1H27 B;  4BCN B;  1UGQ B;  3DJB A;  4AI6 A;  2BPM B;  3QZ9 B;  3NDQ A;  1VIN A;  3EJ1 B;  4TTH A;  1H26 B;  2W9Z A;  3DL1 A;  2ZPF B;  5L2W B;  1D3U B;  3BLQ B;  1UNH D;  2UUE B;  3VKH A;  4CFM B;  4BCG B;  3HB9 A;  2BS2 A;  2PJQ A;  4ZGE B;  4M6V A;  5FGK B;  2QQ8 A;  2JGZ B;  1N4M A;  4OB0 B;  2WHB B;  4FM4 B;  2QGS A;  4EC9 B;  4BCP B;  3BLH B;  4CFU B;  1AIS B;  3DDQ B;  4BCJ B;  4YC3 B;  4G6L B;  2CYZ B;  4BCQ B;  2DXB B;  4CRL B;  2ZCF B;  5IF1 B;  2DPP B;  2D0Q B;  5HNB B;  4KRD B;  1JKW A;  2R7G A;  2C5X B;  4CFV B;  1OL1 B;  4OB1 B;  5IHY A;  2BS3 A;  1PKD B;  4EOR B;  4F7L B;  3KHI A;  1VOL A;  5BNJ B;  1E7P A;  1GUX B;  2DD4 B;  5EJC A;  2X1N B;  2WEV B;  2AHJ B;  5IDP B;  4BY7 X;  1E9H B;  1G3N C;  2C5N B;  1O9K B;  4BCI B;  2C5O B;  4BCM B;  1OL2 B;  2WXV B;  3BLR B;  4ROE A;  1QLB A;  2C5V B;  2QF7 A;  3RGF B;  3HZJ A;  2WJ9 A;  4HNT A;  1VYW B;  4EOO B;  1TFB A;  4IMY B;  3QHW B;  4HNV A;  3VYG B;  5DQV A;  5HBJ B;  1UNL D;  3HHT B;  2WIH B;  3QYG B;  2BS4 A;  2UZE B;  2WPA B;  4OB3 B;  2DME A;  5HVY B;  4JX5 A;  2C6T B;  3A8H B;  2W96 A;  3QWL A;  4EOK B;  2IW8 B;  2CCI B;  1OKV B;  4EOS B;  1UGP B;  3BG9 A;  2QFZ A;  3H4C A;  1ZP2 A;  2PMI B;  1W98 B;  2PK9 B;  4EOP B;  4EOQ B;  4YOO A;  2B9R A;  1XO2 A;  4YOZ A;  4F70 B;  1GUX A;  1H1Q B;  5CYI B;  4NST B;  3EID B;  1JSU B;  4LOC A;  1H4L D;  3BG5 A;  2W9F A;  3POM A;  3X24 B;  1V29 B;  2ZPG B;  4ROD A;  4BCK B;  4BCN D;  2UZB B;  2BKZ B;  2PHG A;  1ENW A;  4MIM A;  3WVD B;  1O9K A;  2QDJ A;  2I53 A;  1AD6 A;  4MFD A;  4AKG A;  4HLQ A;  4NC6 A;  2IVX A;  5HQ0 B;  3DOG B;  2WFY B;  1OGU B;  4ELJ A;  3HO8 A;  3PO3 S;  2CJM B;  4UN0 A;  2WMA B;  1QMZ B;  3QYE A;  4I3Z B;  4EOI B;  5HBH B;  4JX6 A;  4MFE A;  3HBL A;  1TD6 A;  2UZD B;  2CCH B;  3TW7 A;  2F2C A;  3BHV B;  1GY3 B;  1H25 B;  4EOM B;  3TN8 B;  4BCH B;  3BHU B;  4F6S B;  3F5X B;  3LQ5 B;  3VKG A;  3MY1 B;  1OIU B;  5ACB A;  4ROC A;  4Y72 B;  4BCQ D;  4F7S B;  1P5E B;  2KR6 A;  1UGR B;  4F6U B;  4ZGD B;  4BBS M;  2W2H A;  3VYH B;  2ZPB B;  5HBE B;  3BG3 A;  2DD5 B;  2IW9 B;  4QSH A;  1URC B;  2LW4 A;  3B57 A;  2CZ1 B;  3MY5 B;  4BBR M;  1H28 B;  3TNW B;  5LMK B;  3X25 B;  2ZZD B;  5ICP B;  3DTO A;  3TNH B;  3TNI B;  2IW6 B;  4FX3 B;  2G77 A;  5IDN B;  2C4G B;  4CFX B;  4BXX X;  2UZL B;  3QZ5 B;  3M03 A;  1H1S B;  4ELL A;  4AKH A;  3X26 B;  3MI9 B;  4BCM D;  1GH6 B;  4CFW B;  4OR5 B;  4CFN B;  4OB2 B;  4OGR B;  3G33 B;  4EC8 B;  2EUF A;  2W99 A;  1IRE B;  3O0G D;  5CEI B;  3TW6 A;  3A8M B;  5EFQ B;  1H1P B;  3K7A M;  4F6W B;  3WVE B;  2ZPI B;  1F5Q B;  4ZGJ B;  3GTM S;  3QYH B;  1H24 B;  1FKM A;  4F7J B;  1FIN B;  1C9B A;  3A8L B;  1BU2 A;  3MIA B;  4EOJ B;  3DDP B;  5I5Z B;  2I40 B;  1H1R B;  4Z6Y A;  1OKW B;  4HNU A;  2PK2 A;  4AKI A;  2ZPH B;  2DXC B;  1JOW A;  4BY1 X;  4BCF B;  4EON B;  4CFU D;  5DQW A;  4BCO B;  2CZ0 B;  3QXE B;  3BHT B;  2IN3 A;  3X20 B;  1OIY B;  2QDY B;  2WIP B;  2V22 B;  1JST B;  3QHR B;  3A8G B;  2WMB B;  1UGS B;  4HL4 A;  4EOL B;  2G9X B;  2KMG A;  1AHJ B;  4JX4 A;  5LQF B;  2CZ7 B;  2ZPE B;  3A8O B;  4F7N B; 
#chains in the Genus database with same CATH homology
 2AHJ B;  4OB2 B;  3WVD B;  2QDJ A;  4MFD A;  4AKG A;  4HLQ A;  4NC6 A;  2CZ6 B;  3QYB A;  3X28 B;  4ELJ A;  3HO8 A;  1IRE B;  3TW6 A;  3A8M B;  1UGQ B;  4AI6 A;  3QYE A;  3QZ9 B;  1QLB A;  2QF7 A;  4JX6 A;  4MFE A;  3HZJ A;  3HBL A;  3WVE B;  2ZPI B;  2WJ9 A;  4ZGJ B;  4HNT A;  3QYH B;  1FKM A;  3DL1 A;  3TW7 A;  2ZPF B;  4HNV A;  3VYG B;  3A8L B;  3VKH A;  3HB9 A;  2BS2 A;  3HHT B;  4ZGE B;  4M6V A;  3QYG B;  3VKG A;  2BS4 A;  2QQ8 A;  4OB3 B;  4OB0 B;  4FM4 B;  4Z6Y A;  4HNU A;  2KR6 A;  4JX5 A;  1UGR B;  3A8H B;  4AKI A;  4ZGD B;  4BBS M;  3QWL A;  3VYH B;  2ZPB B;  2ZPH B;  2DXC B;  3BG3 A;  2DD5 B;  4QSH A;  1UGP B;  3BG9 A;  2QFZ A;  3H4C A;  2CZ1 B;  4BBR M;  2CYZ B;  2DXB B;  3X25 B;  2ZZD B;  2ZCF B;  2CZ0 B;  2DPP B;  2D0Q B;  3QXE B;  2G77 A;  3X20 B;  2QDY B;  4OB1 B;  2BS3 A;  4LOC A;  3A8G B;  3BG5 A;  3QZ5 B;  3X24 B;  1V29 B;  1UGS B;  3KHI A;  2ZPG B;  4HL4 A;  1E7P A;  2DD4 B;  5EJC A;  4AKH A;  2KMG A;  3X26 B;  1AHJ B;  4JX4 A;  2CZ7 B;  2ZPE B;  3A8O B;  4MIM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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