2KR6A

Solution structure of presenilin-1 ctf subunit
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
176
structure length
176
Chain Sequence
MVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of presenilin-1 CTF subunit
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Presenilin-1
total genus 28
structure length 176
sequence length 176
ec nomenclature ec 3.4.23.-:
pdb deposition date 2009-12-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.100 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2kr6A01
2KR6A
chains in the Genus database with same CATH superfamily
5IDNB 4KRDB 3HHTB 4BCND 5CYIB 3F5XB 2CJMB 4MFEA 4ROEA 4Y72B 1GUXB 2X1NB 1UGSB 1C9BA 4ZGDB 3X28B 3K7AM 2R7GA 2WMAB 1JOWA 4QSHA 2DXCB 5I5ZB 4OB3B 3O0GD 4EOPB 3X26B 4CXAB 1H1SB 1W98B 5FGKB 1F5QB 1P5EB 4BCMB 2ZPEB 4AI6A 4OB1B 2C5XB 1VOLA 3WVDB 1QMZB 1UNGD 4CFNB 2WIHB 4OB2B 3VKHA 2CCIB 1AD6A 3M03A 1VYWB 3MI9B 2IW9B 3KHIA 4G6LB 3HO8A 4CFVB 1URCB 3BLRB 3G33B 5DQWA 2PJQA 3BLHB 2CZ6B 4EOOB 4EOIB 4BCIB 4Z6YA 2ZZDB 3DJBA 3EIDB 4F6WB 2WPAB 3BLQB 2PK2A 1O9KB 4NC6A 1OGUB 4F7SB 4OR5B 2LW4A 3QZ5B 4AKIA 3BHTB 1H28B 4KRCB 4ZGJB 3QYBA 1OKWB 3HBLA 5IDPB 1OL2B 1AHJB 5HBJB 4EOMB 1H1RB 3A8OB 1JSTB 2C5VB 1GY3B 4BCJB 3TN8B 2QGSA 3HZJA 4AKGA 4BY7X 3DL1A 2DXBB 2BPMB 3QHWB 2CZ7B 5LMKB 1H26B 2DD4B 4CFWB 4JX6A 2D0QB 3VYGB 3LQ5B 2UZBB 2C6TB 5ACBA 1JKWA 1OI9B 5ICPB 3MIAB 2QDYB 4BCQB 4ELJA 2KMGA 1D3UB 1UNLD 1N4MA 2EUFA 4IMYB 2C4GB 2W96A 3BHUB 5HQ0B 2DPPB 3BG5A 2V22B 4BXXX 1GH6B 2BS4A 4EOLB 4YOZA 3QYEA 2WFYB 3QHRB 2BS2A 2IW8B 2WEVB 1H1PB 4EOJB 4BCHB 2BS3A 2G77A 2WHBB 5HBEB 2ZPFB 2DMEA 4YC3B 3QWLA 4F70B 3TNWB 2UZDB 1GUXA 2UUEB 2WMBB 2ZPHB 2W9ZA 4BCNB 1OL1B 2ZCFB 2QF7A 4MFDA 2IN3A 2KR6A 4EONB 2PHGA 4BBSM 1H1QB 2PMIB 2DD5B 4HL4A 3NDQA 4EOKB 4JX4A 4NSTB 1OIUB 4CFMB 3QYGB 5EJCA 4CFXB 4F6UB 3H4CA 4TTHA 1E7PA 4F7NB 4EC8B 3DTOA 4OGRB 3HB9A 2BKZB 5L2WB 3TW7A 3MY5B 4BCKB 3MY1B 2QFZA 1TFBA 4HLQA 2IVXA 1XO2A 1ZP2A 3TW6A 2I40B 4BCGB 1O9KA 4CFUD 3VYHB 2G9XB 2ZPIB 3WVEB 3EOCB 3X20B 3BG3A 2C5NB 1UGRB 4BCMD 2I53A 5IHYA 1TD6A 1IREB 2F2CA 3A8MB 2W2HA 4AKHA 3DOGB 4YOOA 4EC9B 4M6VA 4F7JB 2PK9B 5HVYB 1UGPB 3X25B 4UN0A 1H25B 4F7LB 1PKDB 2QDJA 4FX3B 3A8LB 4EORB 4OB0B 3QZ9B 2CCHB 2ZPBB 4BCFB 2AHJB 3GTMS 2UZLB 1FINB 1AISB 4CFUB 1H4LD 2UZEB 4F6SB 2CZ0B 5DQVA 4MIMA 1VINA 2CYZB 1H24B 3POMA 3RGFB 5IF1B 2QQ8A 4LOCA 1FKMA 2ZPGB 1G3NC 4EOSB 1UGQB 3TNIB 1UNHD 3QXEB 5HNBB 4BY1X 4CRLB 3EJ1B 4ZGEB 2WIPB 4BCPB 3QYHB 4JX5A 2WJ9A 2JGZB 3PO3S 4HNVA 2W99A 3X24B 2CZ1B 5BNJB 4BCOB 2C5OB 2B9RA 4FM4B 3BHVB 3BG9A 5CEIB 1JSUB 3DDPB 4BCQD 4EOQB 4I3ZB 4HNUA 1H27B 2W9FA 3A8HB 4ROCA 4HNTA 3TNHB 3B57A 1ENWA 1E9HB 4YOSA 1FVVB 2WXVB 5HBHB 3VKGA 4II5B 1BU2A 5EFQB 1V29B 1KXUA 3A8GB 3DDQB 1OIYB 4BBRM 1OKVB 5LQFB 4RODA 1QLBA 4ELLA 2IW6B
chains in the Genus database with same CATH topology
3A8OB 2CZ0B 2KR6A 4BBSM 4MIMA 2DD5B 3HHTB 2CYZB 4HL4A 3HZJA 4JX4A 4AKGA 3DL1A 2QQ8A 2DXBB 4LOCA 3QYGB 1UGSB 1FKMA 5EJCA 2CZ7B 2ZPGB 4ZGDB 3X28B 2DD4B 4JX6A 2D0QB 3H4CA 4QSHA 2DXCB 1UGQB 1E7PA 3VYGB 4OB3B 3HB9A 3X26B 3QXEB 2QDYB 3TW7A 4ZGEB 2ZPEB 3QYHB 4JX5A 2WJ9A 2KMGA 4OB1B 4ELJA 4AI6A 3WVDB 2QFZA 4HLQA 4HNVA 3TW6A 3X24B 2CZ1B 3VYHB 4OB2B 3VKHA 4FM4B 3BG5A 2DPPB 2ZPIB 3WVEB 3BG9A 3X20B 3BG3A 2BS4A 1UGRB 1IREB 3A8MB 3QYEA 3KHIA 3HO8A 4HNUA 2BS2A 4AKHA 3A8HB 4HNTA 2CZ6B 2BS3A 2ZZDB 4M6VA 2G77A 4Z6YA 2ZPFB 1UGPB 3X25B 3QWLA 4NC6A 3VKGA 2ZPHB 3QZ5B 2QDJA 3A8LB 4AKIA 4OB0B 4ZGJB 3QZ9B 1V29B 3QYBA 2ZCFB 2ZPBB 2AHJB 3A8GB 2QF7A 3HBLA 4BBRM 1AHJB 4MFDA 1QLBA 4MFEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KR6 A; 
#chains in the Genus database with same CATH topology
 5IDN B;  4KRD B;  3HHT B;  4BCN D;  5CYI B;  3F5X B;  2CJM B;  4MFE A;  4ROE A;  4Y72 B;  1GUX B;  2X1N B;  1UGS B;  1C9B A;  4ZGD B;  3X28 B;  3K7A M;  2R7G A;  2WMA B;  1JOW A;  4QSH A;  2DXC B;  5I5Z B;  4OB3 B;  3O0G D;  4EOP B;  3X26 B;  4CXA B;  1H1S B;  1W98 B;  5FGK B;  1F5Q B;  1P5E B;  4BCM B;  2ZPE B;  4AI6 A;  4OB1 B;  2C5X B;  1VOL A;  3WVD B;  1QMZ B;  1UNG D;  4CFN B;  2WIH B;  4OB2 B;  3VKH A;  2CCI B;  1AD6 A;  3M03 A;  1VYW B;  3MI9 B;  2IW9 B;  3KHI A;  4G6L B;  3HO8 A;  4CFV B;  1URC B;  3BLR B;  3G33 B;  5DQW A;  2PJQ A;  3BLH B;  2CZ6 B;  4EOO B;  4EOI B;  4BCI B;  4Z6Y A;  2ZZD B;  3DJB A;  3EID B;  4F6W B;  2WPA B;  3BLQ B;  2PK2 A;  1O9K B;  4NC6 A;  1OGU B;  4F7S B;  4OR5 B;  2LW4 A;  3QZ5 B;  4AKI A;  3BHT B;  1H28 B;  4KRC B;  4ZGJ B;  3QYB A;  1OKW B;  3HBL A;  5IDP B;  1OL2 B;  1AHJ B;  5HBJ B;  4EOM B;  1H1R B;  3A8O B;  1JST B;  2C5V B;  1GY3 B;  4BCJ B;  3TN8 B;  2QGS A;  3HZJ A;  4AKG A;  4BY7 X;  3DL1 A;  2DXB B;  2BPM B;  3QHW B;  2CZ7 B;  5LMK B;  1H26 B;  2DD4 B;  4CFW B;  4JX6 A;  2D0Q B;  3VYG B;  3LQ5 B;  2UZB B;  2C6T B;  5ACB A;  1JKW A;  1OI9 B;  5ICP B;  3MIA B;  2QDY B;  4BCQ B;  4ELJ A;  2KMG A;  1D3U B;  1UNL D;  1N4M A;  2EUF A;  4IMY B;  2C4G B;  2W96 A;  3BHU B;  5HQ0 B;  2DPP B;  3BG5 A;  2V22 B;  4BXX X;  1GH6 B;  2BS4 A;  4EOL B;  4YOZ A;  3QYE A;  2WFY B;  3QHR B;  2BS2 A;  2IW8 B;  2WEV B;  1H1P B;  4EOJ B;  4BCH B;  2BS3 A;  2G77 A;  2WHB B;  5HBE B;  2ZPF B;  2DME A;  4YC3 B;  3QWL A;  4F70 B;  3TNW B;  2UZD B;  1GUX A;  2UUE B;  2WMB B;  2ZPH B;  2W9Z A;  4BCN B;  1OL1 B;  2ZCF B;  2QF7 A;  4MFD A;  2IN3 A;  2KR6 A;  4EON B;  2PHG A;  4BBS M;  1H1Q B;  2PMI B;  2DD5 B;  4HL4 A;  3NDQ A;  4EOK B;  4JX4 A;  4NST B;  1OIU B;  4CFM B;  3QYG B;  5EJC A;  4CFX B;  4F6U B;  3H4C A;  4TTH A;  1E7P A;  4F7N B;  4EC8 B;  3DTO A;  4OGR B;  3HB9 A;  2BKZ B;  5L2W B;  3TW7 A;  3MY5 B;  4BCK B;  3MY1 B;  2QFZ A;  1TFB A;  4HLQ A;  2IVX A;  1XO2 A;  1ZP2 A;  3TW6 A;  2I40 B;  4BCG B;  1O9K A;  4CFU D;  3VYH B;  2G9X B;  2ZPI B;  3WVE B;  3EOC B;  3X20 B;  3BG3 A;  2C5N B;  1UGR B;  4BCM D;  2I53 A;  5IHY A;  1TD6 A;  1IRE B;  2F2C A;  3A8M B;  2W2H A;  4AKH A;  3DOG B;  4YOO A;  4EC9 B;  4M6V A;  4F7J B;  2PK9 B;  5HVY B;  1UGP B;  3X25 B;  4UN0 A;  1H25 B;  4F7L B;  1PKD B;  2QDJ A;  4FX3 B;  3A8L B;  4EOR B;  4OB0 B;  3QZ9 B;  2CCH B;  2ZPB B;  4BCF B;  2AHJ B;  3GTM S;  2UZL B;  1FIN B;  1AIS B;  4CFU B;  1H4L D;  2UZE B;  4F6S B;  2CZ0 B;  5DQV A;  4MIM A;  1VIN A;  2CYZ B;  1H24 B;  3POM A;  3RGF B;  5IF1 B;  2QQ8 A;  4LOC A;  1FKM A;  2ZPG B;  1G3N C;  4EOS B;  1UGQ B;  3TNI B;  1UNH D;  3QXE B;  5HNB B;  4BY1 X;  4CRL B;  3EJ1 B;  4ZGE B;  2WIP B;  4BCP B;  3QYH B;  4JX5 A;  2WJ9 A;  2JGZ B;  3PO3 S;  4HNV A;  2W99 A;  3X24 B;  2CZ1 B;  5BNJ B;  4BCO B;  2C5O B;  2B9R A;  4FM4 B;  3BHV B;  3BG9 A;  5CEI B;  1JSU B;  3DDP B;  4BCQ D;  4EOQ B;  4I3Z B;  4HNU A;  1H27 B;  2W9F A;  3A8H B;  4ROC A;  4HNT A;  3TNH B;  3B57 A;  1ENW A;  1E9H B;  4YOS A;  1FVV B;  2WXV B;  5HBH B;  3VKG A;  4II5 B;  1BU2 A;  5EFQ B;  1V29 B;  1KXU A;  3A8G B;  3DDQ B;  1OIY B;  4BBR M;  1OKV B;  5LQF B;  4ROD A;  1QLB A;  4ELL A;  2IW6 B; 
#chains in the Genus database with same CATH homology
 3A8O B;  2CZ0 B;  2KR6 A;  4BBS M;  4MIM A;  2DD5 B;  3HHT B;  2CYZ B;  4HL4 A;  3HZJ A;  4JX4 A;  4AKG A;  3DL1 A;  2QQ8 A;  2DXB B;  4LOC A;  3QYG B;  1UGS B;  1FKM A;  5EJC A;  2CZ7 B;  2ZPG B;  4ZGD B;  3X28 B;  2DD4 B;  4JX6 A;  2D0Q B;  3H4C A;  4QSH A;  2DXC B;  1UGQ B;  1E7P A;  3VYG B;  4OB3 B;  3HB9 A;  3X26 B;  3QXE B;  2QDY B;  3TW7 A;  4ZGE B;  2ZPE B;  3QYH B;  4JX5 A;  2WJ9 A;  2KMG A;  4OB1 B;  4ELJ A;  4AI6 A;  3WVD B;  2QFZ A;  4HLQ A;  4HNV A;  3TW6 A;  3X24 B;  2CZ1 B;  3VYH B;  4OB2 B;  3VKH A;  4FM4 B;  3BG5 A;  2DPP B;  2ZPI B;  3WVE B;  3BG9 A;  3X20 B;  3BG3 A;  2BS4 A;  1UGR B;  1IRE B;  3A8M B;  3QYE A;  3KHI A;  3HO8 A;  4HNU A;  2BS2 A;  4AKH A;  3A8H B;  4HNT A;  2CZ6 B;  2BS3 A;  2ZZD B;  4M6V A;  2G77 A;  4Z6Y A;  2ZPF B;  1UGP B;  3X25 B;  3QWL A;  4NC6 A;  3VKG A;  2ZPH B;  3QZ5 B;  2QDJ A;  3A8L B;  4AKI A;  4OB0 B;  4ZGJ B;  3QZ9 B;  1V29 B;  3QYB A;  2ZCF B;  2ZPB B;  2AHJ B;  3A8G B;  2QF7 A;  3HBL A;  4BBR M;  1AHJ B;  4MFD A;  1QLB A;  4MFE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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