The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
25
|
sequence length |
83
|
structure length |
83
|
Chain Sequence |
SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4.
pubmed doi rcsb |
| molecule tags |
Transcription/transferase
|
| source organism |
Homo sapiens
|
| molecule keywords |
Bromodomain-containing protein 4
|
| total genus |
25
|
| structure length |
83
|
| sequence length |
83
|
| ec nomenclature | |
| pdb deposition date | 2016-04-18 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF17035 | BET | Bromodomain extra-terminal - transcription regulation |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Substrate Binding Domain Of Dnak; Chain:A; Domain 2 | Substrate Binding Domain Of Dnak; Chain:A; Domain 2 |
#chains in the Genus database with same CATH superfamily 2ND0 A; 2JNS A; 2N3K A; 2ND1 A; 2NCZ A; #chains in the Genus database with same CATH topology 1TQW A; 3D50 A; 2MI7 A; 1DKX A; 2RAK A; 2F7R A; 4HY9 A; 3A98 A; 3D2F A; 4HR1 A; 2F7O A; 4JWC A; 1PS3 A; 2X3X A; 3DX3 A; 4AVM A; 2EFK A; 4BNE A; 4UDX X; 3LVT A; 3VEA A; 2PY6 A; 4EZP A; 3DPQ A; 4HYB A; 4AZG A; 4IW0 A; 3Q0K A; 2RAI A; 2WYH A; 4PO2 A; 2F7Q A; 3QNI A; 1ZYL A; 2LM0 A; 2GA9 D; 3BLB A; 2OBL A; 3F7W A; 3KAV A; 3DX1 A; 3Q84 A; 3B51 X; 3FD9 A; 4EZQ A; 3CKD A; 3D2E A; 1E9V A; 4AZI A; 4F01 A; 2C08 A; 4R5G A; 1X04 A; 2X3V A; 1GN9 A; 2EWF A; 3O3N B; 1TQV A; 2RT6 A; 2O0I 1; 3VKH A; 2EFL A; 2QFF A; 4AZC B; 3LLL A; 5E84 A; 1TQT A; 2OO2 A; 3BVT A; 4WPC A; 3SYV A; 2PMR A; 1OA0 A; 3CVR A; 1SU6 A; 3KAW A; 4JLC A; 1LQ7 A; 3O3M B; 4JWI A; 2X3W A; 3D4Z A; 3L3O M; 3T49 A; 4H8S A; 4HR1 B; 3D4Y A; 1R33 A; 4JNE A; 3I2W A; 3ZED A; 2YLL A; 3QA8 A; 5TKY A; 3ABH A; 2YLA A; 4R5K A; 4KIK A; 4EZV A; 3BUP A; 4DYL A; 3RV0 A; 1O7D C; 1OAO A; 2FYV A; 3OHX M; 2YL9 A; 4FM3 A; 4JNF A; 2KHO A; 1O7D B; 3DX0 A; 3VEB A; 4E3C A; 1I4T A; 3T48 A; 3HAJ A; 2Z0V A; 1I49 A; 3I39 X; 1TQU A; 3C7N A; 1UPX A; 3OWG A; 1SU7 A; 2ALW A; 2F1A A; 3ER8 C; 1X03 A; 3DYT A; 4D8J A; 3M3W A; 3I04 A; 4AZB A; 2ZXQ A; 1URU A; 3O3O B; 4EZR A; 4DCN C; 1QWU A; 3DDG A; 3EJQ A; 4G6Q A; 4AZ6 A; 3EJT A; 2F7P A; 2D1L A; 3EJU A; 3HAI A; 4EZS A; 5C5B A; 2RAJ A; 2JNK A; 3DDF A; 1HXK A; 3CZN A; 4NPH A; 3SOG A; 3RPM A; 2FIC A; 2ND0 A; 4AZ7 A; 3EJP A; 4FZP A; 3BVX A; 3EJS A; 4R5L A; 1JQK A; 1W9M A; 3B53 X; 2YIV X; 2V0O A; 4H6I A; 1R5E A; 3UIT A; 4EZN A; 4EZW A; 2WYI A; 1OA1 A; 4EZU A; 4FZO A; 2WIN M; 4F00 A; 3BVW A; 4KIK B; 2YI8 A; 4H6H A; 4EZO A; 1SU8 A; 3D51 A; 2YI9 A; 4AZ5 A; 2JNS A; 4WPE A; 3BUD A; 2GAF D; 3B52 X; 1E1D A; 4R5I A; 1E2U A; 2OBM A; 3DPO A; 4IM2 A; 3BUI A; 3I01 A; 3BUB A; 3ERC C; 1YWM A; 4IWO A; 3PLT A; 2OW7 A; 2QKW A; 2ELB A; 2YKT A; 3CV5 A; 2ND1 A; 4JWD A; 3RV1 A; 3CAZ A; 4B9Q A; 3T46 A; 2OZN B; 1I4D A; 2OW6 A; 2N3K A; 3ACO A; 3GI7 A; 2F18 A; 1HTY A; 2F1B A; 2Q13 A; 3D52 A; 3BUQ A; 2Z0N A; 2Q12 A; 4IWQ A; 1MJG A; 5C5B B; 2X5C A; 4EZY A; 1R34 A; 4M0M A; 1WDZ A; 3KDR A; 3HAH A; 2YIA A; 1TQS A; 3T4A G; 1SUF A; 3QWE A; 1I4L A; 3DX4 A; 4AKV A; 2YL8 A; 3LMF A; 2GF4 A; 4NSW A; 4UDY X; 2NCZ A; 1DKY A; 3EJR A; 4R5J A; 4IM3 A; 4EZZ A; 3DPP A; 1U00 A; 3QNJ A; 4E81 A; 4FZS A; 2EX3 B; 1HWW A; 3BVV A; 3BVU A; 4IM0 A; 2QXL A; 1QWN A; 5FLE X; 3ER9 B; 3T47 A; 2LXY A; 4I1Q A; 1ZWW A; 3OK8 A; 3L3P A; 4EZX A; 3CZS A; 4JWE A; 4IWP A; 1Y2O A; 5KBP A; 2YL6 A; 2Z8Y A; 1GNL A; 1QX1 A; 1DKZ A; 4JL9 A; 2YL5 A; 1GNT A; 4AZH A; 2YIB A; 4NQI A; 2D4C A; 4AZC A; 3QE6 A; 4EZT A; 3G9G A; 2Z0O A; 3DX2 A; 5FIG A; 4ATM A; 4JN4 A; #chains in the Genus database with same CATH homology 4EZS A; 5E84 A; 1DKX A; 4NPH A; 4IWQ A; 1MJG A; 2ND0 A; 2X5C A; 4EZY A; 4HY9 A; 1OA0 A; 4M0M A; 3A98 A; 3KDR A; 1SU6 A; 3KAW A; 2YIA A; 4JLC A; 3T4A G; 3D2F A; 1SUF A; 3O3M B; 4HR1 A; 4JWI A; 4R5L A; 4JWC A; 1JQK A; 1W9M A; 3B53 X; 2YIV X; 3L3O M; 3T49 A; 4HR1 B; 4H6I A; 3UIT A; 4EZN A; 4EZW A; 4JNE A; 3LMF A; 3ZED A; 4UDX X; 3QA8 A; 5TKY A; 4UDY X; 2NCZ A; 1DKY A; 4R5K A; 4R5J A; 1OA1 A; 4IM3 A; 4EZU A; 4KIK A; 4EZV A; 2PY6 A; 4EZP A; 2WIN M; 3VEA A; 4F00 A; 4EZZ A; 3RV0 A; 3DPP A; 3DPQ A; 1U00 A; 3QNJ A; 1OAO A; 4E81 A; 3OHX M; 4FM3 A; 4HYB A; 4KIK B; 4JNF A; 2EX3 B; 2KHO A; 4IW0 A; 2YI8 A; 4H6H A; 3VEB A; 4IM0 A; 4E3C A; 4PO2 A; 4EZO A; 2QXL A; 1SU8 A; 3T48 A; 2YI9 A; 2JNS A; 1ZYL A; 2GAF D; 3I39 X; 3C7N A; 2LM0 A; 2GA9 D; 5FLE X; 1UPX A; 2OBL A; 3B52 X; 3T47 A; 1E1D A; 4R5I A; 3F7W A; 3KAV A; 1E2U A; 3ER9 B; 3OWG A; 2OBM A; 3B51 X; 3DPO A; 4IM2 A; 3I01 A; 3ERC C; 4IWO A; 1SU7 A; 3FD9 A; 3ER8 C; 4EZQ A; 4EZX A; 4D8J A; 3I04 A; 3D2E A; 1E9V A; 4JWE A; 4IWP A; 2ND1 A; 2Z8Y A; 4F01 A; 1GNL A; 3O3O B; 4EZR A; 4JWD A; 4R5G A; 1DKZ A; 3RV1 A; 4JL9 A; 4B9Q A; 3T46 A; 1GN9 A; 1GNT A; 2EWF A; 2YIB A; 3O3N B; 4EZT A; 2RT6 A; 4G6Q A; 2N3K A; 5FIG A; 3GI7 A; 4JN4 A; 3VKH A; 2QFF A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
