2QFZA

Crystal structure of human tbc1 domain family member 22a
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
313
structure length
300
Chain Sequence
SRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEYFAFIEHYHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIETVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAHWDDEDISLLLAEAYRLKFAF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
Updating...
connected with : NaN
molecule tags Hydrolase activator
source organism Homo sapiens
publication title Crystal structure of human TBC1 domain family member 22A.
rcsb
molecule keywords TBC1 domain family member 22A
total genus 121
structure length 300
sequence length 313
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-06-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00566 RabGAP-TBC Rab-GTPase-TBC domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.80 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2qfzA02
2QFZA 1FKMA 2QQ8A 3HZJA 4HL4A 2G77A 3QYEA 4Z6YA 3QWLA 4HLQA 5EJCA 4NC6A 3QYBA
chains in the Genus database with same CATH superfamily
3A8OB 3X20B 3DDPB 2G77A 3MY5B 1IREB 3MI9B 3X28B 1GH6B 1JKWA 2IN3A 4F7NB 3DTOA 1W98B 4BCKB 4YOOA 5EJCA 4ROCA 3DL1A 5HVYB 2ZZDB 4EC8B 3DOGB 3QZ5B 1N4MA 2DPPB 2CZ0B 3WVEB 4M6VA 4F6WB 2IVXA 3A8GB 4OB0B 2BS4A 2AHJB 3TNIB 1G3NC 3BG9A 4JX4A 1E9HB 1JSUB 1H4LD 1JSTB 1V29B 2PHGA 5IDNB 1FKMA 4HL4A 2DMEA 5HBHB 2ZPIB 2C5XB 3LQ5B 1OGUB 3H4CA 4HLQA 4YOZA 4JX5A 3MIAB 4Y72B 4F7LB 4HNUA 5IHYA 5ACBA 1H1RB 2QFZA 2X1NB 1H1QB 1D3UB 3VKHA 4F6UB 3QWLA 1PKDB 4BCIB 2IW6B 2BS2A 4EOKB 1O9KB 3HBLA 4BCHB 4BCGB 3HZJA 4TTHA 5L2WB 4BCNB 1H26B 4EOSB 2CJMB 4MFDA 4EC9B 1GUXA 3EOCB 4MIMA 4LOCA 2BS3A 3HO8A 5HNBB 2I40B 4RODA 1H28B 4ROEA 3VYHB 2R7GA 3QYEA 4CFMB 3GTMS 3TW6A 4UN0A 2C6TB 2DXCB 1KXUA 4EOOB 1C9BA 1UGPB 4BBSM 2V22B 3QYGB 3X26B 3POMA 1OL2B 3VYGB 5HQ0B 2D0QB 3TNWB 2PJQA 2C4GB 2UZEB 3VKGA 4F7SB 2W9ZA 3TW7A 4ZGDB 2I53A 1UNHD 2ZCFB 2ZPFB 5CYIB 3HHTB 4ELLA 3DDQB 2IW8B 4I3ZB 1OKWB 3B57A 4OGRB 1VOLA 3TNHB 4OB2B 2CCIB 1UGQB 3WVDB 4CFUD 1FVVB 5IF1B 5HBJB 4HNTA 2KR6A 5EFQB 3X24B 3G33B 2PMIB 5ICPB 2QGSA 3HB9A 4ELJA 4BBRM 4AKGA 4JX6A 3F5XB 1UGRB 2WIPB 2WPAB 4CRLB 4YOSA 2WXVB 2EUFA 1O9KA 4BCQD 2CZ6B 5BNJB 2CCHB 1AD6A 2JGZB 5LMKB 2UZLB 1F5QB 4F7JB 4IMYB 5DQVA 2KMGA 4AKHA 1OL1B 1UGSB 2LW4A 4ZGJB 4AI6A 2BKZB 2W96A 2DD5B 4NC6A 3EIDB 1H25B 2PK9B 2UZBB 4EOJB 1P5EB 1AHJB 5FGKB 2ZPGB 5I5ZB 3BG3A 1OIUB 4BCMD 2C5NB 2WIHB 2C5OB 3X25B 4FM4B 1H1SB 1E7PA 1H27B 2CZ7B 1OIYB 4EOIB 4OB3B 4EOLB 1VYWB 3BHVB 4Z6YA 3BHTB 1OI9B 3O0GD 4BCMB 3A8MB 1VINA 1H24B 2CZ1B 2QDJA 2QQ8A 4CXAB 1GY3B 5HBEB 2BPMB 1URCB 5IDPB 4II5B 3K7AM 3BLHB 3A8LB 4G6LB 5CEIB 2B9RA 2WEVB 2UZDB 4BY7X 4CFWB 3BHUB 4CFNB 3BG5A 4QSHA 4NSTB 4OB1B 4ZGEB 5LQFB 4EOQB 2ZPHB 1JOWA 4AKIA 4EONB 2WFYB 1QLBA 3DJBA 1TFBA 1UNGD 5DQWA 3M03A 2G9XB 2W9FA 2QF7A 3QXEB 2DXBB 4BCOB 4BCJB 1UNLD 2DD4B 4KRCB 2C5VB 4BCFB 4CFUB 2PK2A 3QYHB 1H1PB 4BCND 1FINB 1ENWA 2W2HA 2ZPEB 3KHIA 2QDYB 3PO3S 3MY1B 2W99A 4BCPB 3NDQA 1OKVB 2CYZB 1QMZB 3QHWB 2IW9B 4BCQB 3RGFB 3QZ9B 2ZPBB 4BXXX 1XO2A 3QHRB 2F2CA 3TN8B 4F70B 4HNVA 4KRDB 4FX3B 2WHBB 1GUXB 2WJ9A 4OR5B 4CFVB 2WMAB 3BLQB 4EOMB 3EJ1B 2UUEB 3QYBA 1AISB 4F6SB 3BLRB 1BU2A 1ZP2A 4CFXB 4YC3B 4MFEA 4EORB 4BY1X 2WMBB 1TD6A 3A8HB 4EOPB
chains in the Genus database with same CATH topology
3A8OB 3X20B 2ZPHB 2G77A 4AKIA 1IREB 3X28B 1QLBA 3VYHB 3QYEA 2KMGA 4AKHA 1UGSB 3TW6A 4ZGJB 4AI6A 5EJCA 2DD5B 3DL1A 4NC6A 2QF7A 3QXEB 2DXBB 2ZZDB 2DXCB 2DD4B 3QZ5B 1AHJB 3QYHB 2DPPB 2ZPGB 3BG3A 1UGPB 2CZ0B 4BBSM 3WVEB 4M6VA 3QYGB 3X26B 2ZPEB 3VYGB 3KHIA 3A8GB 4OB0B 2BS4A 3X25B 2AHJB 2D0QB 2QDYB 4FM4B 3BG9A 4JX4A 1E7PA 3VKGA 2CYZB 2CZ7B 1V29B 3TW7A 4ZGDB 1FKMA 4HL4A 2ZCFB 2ZPFB 3QZ9B 4OB3B 2ZPBB 2ZPIB 3HHTB 4Z6YA 3H4CA 4HLQA 4JX5A 3A8MB 4OB2B 2CZ1B 1UGQB 2QDJA 4HNUA 2QFZA 2QQ8A 4HNVA 3VKHA 3WVDB 3QWLA 2WJ9A 4HNTA 2KR6A 3X24B 2BS2A 3A8LB 3HBLA 3QYBA 3HZJA 3HB9A 4ELJA 4BBRM 4AKGA 4JX6A 4MFEA 1UGRB 4MFDA 4MIMA 3BG5A 4QSHA 4LOCA 4OB1B 2BS3A 4ZGEB 3A8HB 3HO8A 2CZ6B
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2QFZ A;  1FKM A;  2QQ8 A;  3HZJ A;  4HL4 A;  2G77 A;  3QYE A;  4Z6Y A;  3QWL A;  4HLQ A;  5EJC A;  4NC6 A;  3QYB A; 
#chains in the Genus database with same CATH topology
 3A8O B;  3X20 B;  3DDP B;  2G77 A;  3MY5 B;  1IRE B;  3MI9 B;  3X28 B;  1GH6 B;  1JKW A;  2IN3 A;  4F7N B;  3DTO A;  1W98 B;  4BCK B;  4YOO A;  5EJC A;  4ROC A;  3DL1 A;  5HVY B;  2ZZD B;  4EC8 B;  3DOG B;  3QZ5 B;  1N4M A;  2DPP B;  2CZ0 B;  3WVE B;  4M6V A;  4F6W B;  2IVX A;  3A8G B;  4OB0 B;  2BS4 A;  2AHJ B;  3TNI B;  1G3N C;  3BG9 A;  4JX4 A;  1E9H B;  1JSU B;  1H4L D;  1JST B;  1V29 B;  2PHG A;  5IDN B;  1FKM A;  4HL4 A;  2DME A;  5HBH B;  2ZPI B;  2C5X B;  3LQ5 B;  1OGU B;  3H4C A;  4HLQ A;  4YOZ A;  4JX5 A;  3MIA B;  4Y72 B;  4F7L B;  4HNU A;  5IHY A;  5ACB A;  1H1R B;  2QFZ A;  2X1N B;  1H1Q B;  1D3U B;  3VKH A;  4F6U B;  3QWL A;  1PKD B;  4BCI B;  2IW6 B;  2BS2 A;  4EOK B;  1O9K B;  3HBL A;  4BCH B;  4BCG B;  3HZJ A;  4TTH A;  5L2W B;  4BCN B;  1H26 B;  4EOS B;  2CJM B;  4MFD A;  4EC9 B;  1GUX A;  3EOC B;  4MIM A;  4LOC A;  2BS3 A;  3HO8 A;  5HNB B;  2I40 B;  4ROD A;  1H28 B;  4ROE A;  3VYH B;  2R7G A;  3QYE A;  4CFM B;  3GTM S;  3TW6 A;  4UN0 A;  2C6T B;  2DXC B;  1KXU A;  4EOO B;  1C9B A;  1UGP B;  4BBS M;  2V22 B;  3QYG B;  3X26 B;  3POM A;  1OL2 B;  3VYG B;  5HQ0 B;  2D0Q B;  3TNW B;  2PJQ A;  2C4G B;  2UZE B;  3VKG A;  4F7S B;  2W9Z A;  3TW7 A;  4ZGD B;  2I53 A;  1UNH D;  2ZCF B;  2ZPF B;  5CYI B;  3HHT B;  4ELL A;  3DDQ B;  2IW8 B;  4I3Z B;  1OKW B;  3B57 A;  4OGR B;  1VOL A;  3TNH B;  4OB2 B;  2CCI B;  1UGQ B;  3WVD B;  4CFU D;  1FVV B;  5IF1 B;  5HBJ B;  4HNT A;  2KR6 A;  5EFQ B;  3X24 B;  3G33 B;  2PMI B;  5ICP B;  2QGS A;  3HB9 A;  4ELJ A;  4BBR M;  4AKG A;  4JX6 A;  3F5X B;  1UGR B;  2WIP B;  2WPA B;  4CRL B;  4YOS A;  2WXV B;  2EUF A;  1O9K A;  4BCQ D;  2CZ6 B;  5BNJ B;  2CCH B;  1AD6 A;  2JGZ B;  5LMK B;  2UZL B;  1F5Q B;  4F7J B;  4IMY B;  5DQV A;  2KMG A;  4AKH A;  1OL1 B;  1UGS B;  2LW4 A;  4ZGJ B;  4AI6 A;  2BKZ B;  2W96 A;  2DD5 B;  4NC6 A;  3EID B;  1H25 B;  2PK9 B;  2UZB B;  4EOJ B;  1P5E B;  1AHJ B;  5FGK B;  2ZPG B;  5I5Z B;  3BG3 A;  1OIU B;  4BCM D;  2C5N B;  2WIH B;  2C5O B;  3X25 B;  4FM4 B;  1H1S B;  1E7P A;  1H27 B;  2CZ7 B;  1OIY B;  4EOI B;  4OB3 B;  4EOL B;  1VYW B;  3BHV B;  4Z6Y A;  3BHT B;  1OI9 B;  3O0G D;  4BCM B;  3A8M B;  1VIN A;  1H24 B;  2CZ1 B;  2QDJ A;  2QQ8 A;  4CXA B;  1GY3 B;  5HBE B;  2BPM B;  1URC B;  5IDP B;  4II5 B;  3K7A M;  3BLH B;  3A8L B;  4G6L B;  5CEI B;  2B9R A;  2WEV B;  2UZD B;  4BY7 X;  4CFW B;  3BHU B;  4CFN B;  3BG5 A;  4QSH A;  4NST B;  4OB1 B;  4ZGE B;  5LQF B;  4EOQ B;  2ZPH B;  1JOW A;  4AKI A;  4EON B;  2WFY B;  1QLB A;  3DJB A;  1TFB A;  1UNG D;  5DQW A;  3M03 A;  2G9X B;  2W9F A;  2QF7 A;  3QXE B;  2DXB B;  4BCO B;  4BCJ B;  1UNL D;  2DD4 B;  4KRC B;  2C5V B;  4BCF B;  4CFU B;  2PK2 A;  3QYH B;  1H1P B;  4BCN D;  1FIN B;  1ENW A;  2W2H A;  2ZPE B;  3KHI A;  2QDY B;  3PO3 S;  3MY1 B;  2W99 A;  4BCP B;  3NDQ A;  1OKV B;  2CYZ B;  1QMZ B;  3QHW B;  2IW9 B;  4BCQ B;  3RGF B;  3QZ9 B;  2ZPB B;  4BXX X;  1XO2 A;  3QHR B;  2F2C A;  3TN8 B;  4F70 B;  4HNV A;  4KRD B;  4FX3 B;  2WHB B;  1GUX B;  2WJ9 A;  4OR5 B;  4CFV B;  2WMA B;  3BLQ B;  4EOM B;  3EJ1 B;  2UUE B;  3QYB A;  1AIS B;  4F6S B;  3BLR B;  1BU2 A;  1ZP2 A;  4CFX B;  4YC3 B;  4MFE A;  4EOR B;  4BY1 X;  2WMB B;  1TD6 A;  3A8H B;  4EOP B; 
#chains in the Genus database with same CATH homology
 3A8O B;  3X20 B;  2ZPH B;  2G77 A;  4AKI A;  1IRE B;  3X28 B;  1QLB A;  3VYH B;  3QYE A;  2KMG A;  4AKH A;  1UGS B;  3TW6 A;  4ZGJ B;  4AI6 A;  5EJC A;  2DD5 B;  3DL1 A;  4NC6 A;  2QF7 A;  3QXE B;  2DXB B;  2ZZD B;  2DXC B;  2DD4 B;  3QZ5 B;  1AHJ B;  3QYH B;  2DPP B;  2ZPG B;  3BG3 A;  1UGP B;  2CZ0 B;  4BBS M;  3WVE B;  4M6V A;  3QYG B;  3X26 B;  2ZPE B;  3VYG B;  3KHI A;  3A8G B;  4OB0 B;  2BS4 A;  3X25 B;  2AHJ B;  2D0Q B;  2QDY B;  4FM4 B;  3BG9 A;  4JX4 A;  1E7P A;  3VKG A;  2CYZ B;  2CZ7 B;  1V29 B;  3TW7 A;  4ZGD B;  1FKM A;  4HL4 A;  2ZCF B;  2ZPF B;  3QZ9 B;  4OB3 B;  2ZPB B;  2ZPI B;  3HHT B;  4Z6Y A;  3H4C A;  4HLQ A;  4JX5 A;  3A8M B;  4OB2 B;  2CZ1 B;  1UGQ B;  2QDJ A;  4HNU A;  2QFZ A;  2QQ8 A;  4HNV A;  3VKH A;  3WVD B;  3QWL A;  2WJ9 A;  4HNT A;  2KR6 A;  3X24 B;  2BS2 A;  3A8L B;  3HBL A;  3QYB A;  3HZJ A;  3HB9 A;  4ELJ A;  4BBR M;  4AKG A;  4JX6 A;  4MFE A;  1UGR B;  4MFD A;  4MIM A;  3BG5 A;  4QSH A;  4LOC A;  4OB1 B;  2BS3 A;  4ZGE B;  3A8H B;  3HO8 A;  2CZ6 B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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