2WPAB

Optimisation of 6,6-dimethyl pyrrolo 3,4-c pyrazoles: identification of pha-793887, a potent cdk inhibitor suitable for intravenous dosing
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
258
structure length
258
Chain Sequence
VPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
3H1 (200-202)EMPTYAH1 (178-193)AH2 (208-225)TI1 (196-199)TI2 (203-206)AH4 (253-268)3H2 (250-252)AH3 (229-244)Updating...
connected with : NaN
molecule tags Cell cycle
source organism Homo sapiens
publication title Optimization of 6,6-Dimethyl Pyrrolo[3,4-C]Pyrazoles: Identification of Pha-793887, a Potent Cdk Inhibitor Suitable for Intravenous Dosing.
pubmed doi rcsb
molecule keywords CELL DIVISION PROTEIN KINASE 2
total genus 89
structure length 258
sequence length 258
chains with identical sequence D
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00134 Cyclin_N Cyclin, N-terminal domain
B PF02984 Cyclin_C Cyclin, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 2wpaB01
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 2wpaB02
2PK9B 1OKWB 3K7AM 4YC3B 2PHGA 5HBHB 4ELJA 1E9HB 4ROEA 2WIPB 1G3NC 4G6LB 2EUFA 4BCND 2UZEB 1H26B 2WFYB 5HQ0B 4F7LB 2X1NB 1FVVB 1O9KB 4OGRB 5LQFB 3POMA 4BCJB 3LQ5B 4ELLA 1TFBA 2B9RA 1OIUB 2WXVB 4CFVB 4CFNB 1OL2B 1GUXA 2IW9B 3DDPB 2CCIB 3QHRB 4EONB 2PMIB 4ROCA 4CFXB 5IDNB 3DDQB 2IW8B 3MIAB 4BCMB 4I3ZB 4F7NB 5L2WB 3MI9B 4EC8B 5I5ZB 1UNGD 4F7JB 4BCKB 4IMYB 2WHBB 2WMAB 1P5EB 1AISB 1H1SB 4BCIB 3RGFB 1H1RB 4F6SB 1UNLD 1OI9B 1PKDB 4BCHB 1GH6B 2I40B 1URCB 1XO2A 1OL1B 3G33B 4BCPB 3TNWB 2F2CA 4UN0A 4EOPB 4CFWB 3MY1B 2CCHB 1N4MA 1KXUA 4EOQB 1H1PB 4EOIB 4NSTB 1OIYB 3BLHB 3DOGB 5BNJB 4KRCB 2WIHB 1ZP2A 3TNHB 2BPMB 4EOJB 4CXAB 1GUXB 2IW6B 1JKWA 4TTHA 1FINB 3TN8B 2C5NB 1JSTB 4BCQB 2G9XB 2WEVB 4II5B 4EOSB 3QHWB 4CRLB 1QMZB 2QDJA 2C6TB 4BCMD 3EJ1B 4EOMB 3F5XB 2UZBB 5HNBB 2PK2A 5HBJB 1F5QB 1VINA 4YOOA 4BCGB 1W98B 4EOOB 1AD6A 4OR5B 1C9BA 2I53A 4BCFB 1H24B 5CYIB 4BCOB 4YOZA 2W99A 3TNIB 3BHUB 3M03A 1VOLA 2C5XB 3H4CA 1H4LD 1H27B 4FX3B 4F6WB 2V22B 5HBEB 3BHVB 5ACBA 5LMKB 2IVXA 2C4GB 3MY5B 1GY3B 2BKZB 4BCNB 1VYWB 3EIDB 3BLRB 4KRDB 1O9KA 4F7SB 5HVYB 4F6UB 3O0GD 4Y72B 1JOWA 5IF1B 2UUEB 4YOSA 5IDPB 5CEIB 1OGUB 1H25B 4BCQD 4EORB 5ICPB 3EOCB 4F70B 2UZDB 4EC9B 1D3UB 3BHTB 2C5OB 5EFQB 1OKVB 3BLQB 2W9ZA 5FGKB 1H1QB 4EOKB 1UNHD 1JSUB 4CFUB 2WMBB 1H28B 2CJMB 2UZLB 4CFMB 2R7GA 4EOLB 2C5VB 2JGZB 2W96A 4RODA 4CFUD 2W9FA 2W2HA 1BU2A 2WPAB
chains in the Genus database with same CATH superfamily
3DTOA 2WJ9A 2WIPB 1G3NC 3TW6A 3DJBA 2UZEB 2WFYB 5HQ0B 4OGRB 5LQFB 1O9KB 4BCJB 2B9RA 4CFVB 2WXVB 1OL2B 3HBLA 3DDQB 4EC8B 3HB9A 5I5ZB 4F7JB 2WHBB 3A8GB 4QSHA 1URCB 4ZGEB 4BCPB 3TNWB 2AHJB 4NSTB 4KRCB 2WIHB 3QYGB 2BPMB 2G77A 1GUXB 4TTHA 3TN8B 2C5NB 4II5B 3QHWB 2DXBB 2UZBB 5HNBB 4OB3B 4BY1X 4OR5B 2I53A 1AHJB 1UGPB 3B57A 2ZZDB 3QWLA 4HLQA 4HNTA 2BKZB 4BCNB 1E7PA 3EIDB 3BLRB 2IN3A 5HVYB 4ZGDB 4BBRM 5IF1B 4YOSA 5IDPB 4Z6YA 2UZDB 5EFQB 2KR6A 2W9ZA 5FGKB 4CFUB 2WMBB 1H28B 2CJMB 1BU2A 2QFZA 1OKWB 2BS4A 2EUFA 2KMGA 3KHIA 1FVVB 3POMA 1FKMA 3LQ5B 4CFNB 2CZ6B 3DDPB 2CCIB 4ROCA 4CFXB 2IW8B 4BCMB 4F7NB 3MI9B 1UNGD 4BCKB 4IMYB 2QQ8A 3HO8A 4BCIB 1OI9B 1GH6B 1XO2A 3G33B 3WVEB 2F2CA 4UN0A 3DL1A 2LW4A 2CCHB 1N4MA 1KXUA 4AKIA 3X26B 4EOIB 3BLHB 4EOJB 1ZP2A 3X28B 4CXAB 2IW6B 1QLBA 1JSTB 2G9XB 2WEVB 4JX4A 4CRLB 3F5XB 4HL4A 2ZPEB 1W98B 1AD6A 4BCFB 5CYIB 4AKHA 4YOZA 4HNUA 2ZPIB 3BHUB 3M03A 1VOLA 3H4CA 1H27B 4FX3B 4F6WB 2V22B 2ZPHB 3QZ9B 1TD6A 2C4GB 4JX6A 5IHYA 3QYEA 4KRDB 4MIMA 4F6UB 3O0GD 1JOWA 4FM4B 5CEIB 2DMEA 4BCQD 4EORB 1D3UB 3A8HB 2CYZB 1H1QB 1JSUB 4CFMB 2W96A 4RODA 4CFUD 1UGSB 4ELJA 2QF7A 3QYBA 2ZCFB 1H26B 4F7LB 2X1NB 4ELLA 1TFBA 2QGSA 4AI6A 2CZ7B 3QHRB 3NDQA 2PMIB 5IDNB 3QXEB 3MIAB 4I3ZB 5DQVA 2CZ1B 2DD4B 2WMAB 1P5EB 3BG9A 1H1RB 4F6SB 3WVDB 1UNLD 4BCHB 4ZGJB 1OL1B 3X24B 2DXCB 4CFWB 3MY1B 2ZPGB 5BNJB 1OIYB 3TNHB 1JKWA 3HZJA 3VYGB 2C6TB 4EOMB 4AKGA 4OB2B 5HBJB 1F5QB 3X20B 1VINA 3A8MB 4YOOA 4BCGB 2BS3A 1C9BA 3A8OB 1H24B 3A8LB 4BCOB 4BXXX 3PO3S 5HBEB 4M6VA 5ACBA 2IVXA 3MY5B 1VYWB 4MFDA 1O9KA 4F7SB 4Y72B 2UUEB 1UGRB 3VYHB 1H25B 2ZPBB 4F70B 4OB0B 4EC9B 3BHTB 3HHTB 3BG5A 4OB1B 4EOKB 2ZPFB 1UNHD 3QYHB 4LOCA 2UZLB 2W9FA 5EJCA 2WPAB 2PK9B 3K7AM 4YC3B 3GTMS 2PHGA 5HBHB 1E9HB 4ROEA 4G6LB 4BCND 5DQWA 1OIUB 1GUXA 2IW9B 4EONB 5L2WB 2DD5B 3TW7A 1AISB 1H1SB 4BBSM 3RGFB 1PKDB 2I40B 4EOPB 4EOQB 3VKGA 1UGQB 1IREB 1H1PB 3DOGB 1FINB 4BCQB 4EOSB 1QMZB 2QDJA 4NC6A 4BCMD 2CZ0B 3EJ1B 3BG3A 2PK2A 2D0QB 4EOOB 2PJQA 2W99A 4JX5A 3TNIB 2C5XB 1H4LD 2QDYB 3BHVB 5LMKB 1GY3B 4HNVA 1OGUB 5ICPB 1ENWA 3EOCB 2C5OB 4BY7X 1OKVB 3BLQB 2BS2A 2DPPB 2R7GA 3VKHA 4EOLB 2C5VB 2JGZB 2W2HA 4MFEA 1V29B 3QZ5B 3X25B
chains in the Genus database with same CATH topology
2PK9B 1OKWB 3K7AM 4YC3B 2PHGA 5HBHB 4ELJA 1E9HB 4ROEA 2WIPB 1G3NC 4G6LB 2EUFA 4BCND 2UZEB 1H26B 2WFYB 5HQ0B 4F7LB 2X1NB 1FVVB 1O9KB 4OGRB 5LQFB 3POMA 4BCJB 3LQ5B 4ELLA 1TFBA 2B9RA 1OIUB 2WXVB 4CFVB 4CFNB 1OL2B 1GUXA 2IW9B 3DDPB 2CCIB 3QHRB 4EONB 2PMIB 4ROCA 4CFXB 5IDNB 3DDQB 2IW8B 3MIAB 4BCMB 4I3ZB 4F7NB 5L2WB 3MI9B 4EC8B 5I5ZB 1UNGD 4F7JB 4BCKB 4IMYB 2WHBB 2WMAB 1P5EB 1AISB 1H1SB 4BCIB 3RGFB 1H1RB 4F6SB 1UNLD 1OI9B 1PKDB 4BCHB 1GH6B 2I40B 1URCB 1XO2A 1OL1B 3G33B 4BCPB 3TNWB 2F2CA 4UN0A 4EOPB 4CFWB 3MY1B 2CCHB 1N4MA 1KXUA 4EOQB 1H1PB 4EOIB 4NSTB 1OIYB 3BLHB 3DOGB 5BNJB 4KRCB 2WIHB 1ZP2A 3TNHB 2BPMB 4EOJB 4CXAB 1GUXB 2IW6B 1JKWA 4TTHA 1FINB 3TN8B 2C5NB 1JSTB 4BCQB 2G9XB 2WEVB 4II5B 4EOSB 3QHWB 4CRLB 1QMZB 2QDJA 2C6TB 4BCMD 3EJ1B 4EOMB 3F5XB 2UZBB 5HNBB 2PK2A 5HBJB 1F5QB 1VINA 4YOOA 4BCGB 1W98B 4EOOB 1AD6A 4OR5B 1C9BA 2I53A 4BCFB 1H24B 5CYIB 4BCOB 4YOZA 2W99A 3TNIB 3BHUB 3M03A 1VOLA 2C5XB 3H4CA 1H4LD 1H27B 4FX3B 4F6WB 2V22B 5HBEB 3BHVB 5ACBA 5LMKB 2IVXA 2C4GB 3MY5B 1GY3B 2BKZB 4BCNB 1VYWB 3EIDB 3BLRB 4KRDB 1O9KA 4F7SB 5HVYB 4F6UB 3O0GD 4Y72B 1JOWA 5IF1B 2UUEB 4YOSA 5IDPB 5CEIB 1OGUB 1H25B 4BCQD 4EORB 5ICPB 3EOCB 4F70B 2UZDB 4EC9B 1D3UB 3BHTB 2C5OB 5EFQB 1OKVB 3BLQB 2W9ZA 5FGKB 1H1QB 4EOKB 1UNHD 1JSUB 4CFUB 2WMBB 1H28B 2CJMB 2UZLB 4CFMB 2R7GA 4EOLB 2C5VB 2JGZB 2W96A 4RODA 4CFUD 2W9FA 2W2HA 1BU2A 2WPAB
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2PK9 B;  1OKW B;  3K7A M;  4YC3 B;  2PHG A;  5HBH B;  4ELJ A;  1E9H B;  4ROE A;  2WIP B;  1G3N C;  4G6L B;  2EUF A;  4BCN D;  2UZE B;  1H26 B;  2WFY B;  5HQ0 B;  4F7L B;  2X1N B;  1FVV B;  1O9K B;  4OGR B;  5LQF B;  3POM A;  4BCJ B;  3LQ5 B;  4ELL A;  1TFB A;  2B9R A;  1OIU B;  2WXV B;  4CFV B;  4CFN B;  1OL2 B;  1GUX A;  2IW9 B;  3DDP B;  2CCI B;  3QHR B;  4EON B;  2PMI B;  4ROC A;  4CFX B;  5IDN B;  3DDQ B;  2IW8 B;  3MIA B;  4BCM B;  4I3Z B;  4F7N B;  5L2W B;  3MI9 B;  4EC8 B;  5I5Z B;  1UNG D;  4F7J B;  4BCK B;  4IMY B;  2WHB B;  2WMA B;  1P5E B;  1AIS B;  1H1S B;  4BCI B;  3RGF B;  1H1R B;  4F6S B;  1UNL D;  1OI9 B;  1PKD B;  4BCH B;  1GH6 B;  2I40 B;  1URC B;  1XO2 A;  1OL1 B;  3G33 B;  4BCP B;  3TNW B;  2F2C A;  4UN0 A;  4EOP B;  4CFW B;  3MY1 B;  2CCH B;  1N4M A;  1KXU A;  4EOQ B;  1H1P B;  4EOI B;  4NST B;  1OIY B;  3BLH B;  3DOG B;  5BNJ B;  4KRC B;  2WIH B;  1ZP2 A;  3TNH B;  2BPM B;  4EOJ B;  4CXA B;  1GUX B;  2IW6 B;  1JKW A;  4TTH A;  1FIN B;  3TN8 B;  2C5N B;  1JST B;  4BCQ B;  2G9X B;  2WEV B;  4II5 B;  4EOS B;  3QHW B;  4CRL B;  1QMZ B;  2QDJ A;  2C6T B;  4BCM D;  3EJ1 B;  4EOM B;  3F5X B;  2UZB B;  5HNB B;  2PK2 A;  5HBJ B;  1F5Q B;  1VIN A;  4YOO A;  4BCG B;  1W98 B;  4EOO B;  1AD6 A;  4OR5 B;  1C9B A;  2I53 A;  4BCF B;  1H24 B;  5CYI B;  4BCO B;  4YOZ A;  2W99 A;  3TNI B;  3BHU B;  3M03 A;  1VOL A;  2C5X B;  3H4C A;  1H4L D;  1H27 B;  4FX3 B;  4F6W B;  2V22 B;  5HBE B;  3BHV B;  5ACB A;  5LMK B;  2IVX A;  2C4G B;  3MY5 B;  1GY3 B;  2BKZ B;  4BCN B;  1VYW B;  3EID B;  3BLR B;  4KRD B;  1O9K A;  4F7S B;  5HVY B;  4F6U B;  3O0G D;  4Y72 B;  1JOW A;  5IF1 B;  2UUE B;  4YOS A;  5IDP B;  5CEI B;  1OGU B;  1H25 B;  4BCQ D;  4EOR B;  5ICP B;  3EOC B;  4F70 B;  2UZD B;  4EC9 B;  1D3U B;  3BHT B;  2C5O B;  5EFQ B;  1OKV B;  3BLQ B;  2W9Z A;  5FGK B;  1H1Q B;  4EOK B;  1UNH D;  1JSU B;  4CFU B;  2WMB B;  1H28 B;  2CJM B;  2UZL B;  4CFM B;  2R7G A;  4EOL B;  2C5V B;  2JGZ B;  2W96 A;  4ROD A;  4CFU D;  2W9F A;  2W2H A;  1BU2 A;  2WPA B; 
#chains in the Genus database with same CATH topology
 3DTO A;  2WJ9 A;  2WIP B;  1G3N C;  3TW6 A;  3DJB A;  2UZE B;  2WFY B;  5HQ0 B;  4OGR B;  5LQF B;  1O9K B;  4BCJ B;  2B9R A;  4CFV B;  2WXV B;  1OL2 B;  3HBL A;  3DDQ B;  4EC8 B;  3HB9 A;  5I5Z B;  4F7J B;  2WHB B;  3A8G B;  4QSH A;  1URC B;  4ZGE B;  4BCP B;  3TNW B;  2AHJ B;  4NST B;  4KRC B;  2WIH B;  3QYG B;  2BPM B;  2G77 A;  1GUX B;  4TTH A;  3TN8 B;  2C5N B;  4II5 B;  3QHW B;  2DXB B;  2UZB B;  5HNB B;  4OB3 B;  4BY1 X;  4OR5 B;  2I53 A;  1AHJ B;  1UGP B;  3B57 A;  2ZZD B;  3QWL A;  4HLQ A;  4HNT A;  2BKZ B;  4BCN B;  1E7P A;  3EID B;  3BLR B;  2IN3 A;  5HVY B;  4ZGD B;  4BBR M;  5IF1 B;  4YOS A;  5IDP B;  4Z6Y A;  2UZD B;  5EFQ B;  2KR6 A;  2W9Z A;  5FGK B;  4CFU B;  2WMB B;  1H28 B;  2CJM B;  1BU2 A;  2QFZ A;  1OKW B;  2BS4 A;  2EUF A;  2KMG A;  3KHI A;  1FVV B;  3POM A;  1FKM A;  3LQ5 B;  4CFN B;  2CZ6 B;  3DDP B;  2CCI B;  4ROC A;  4CFX B;  2IW8 B;  4BCM B;  4F7N B;  3MI9 B;  1UNG D;  4BCK B;  4IMY B;  2QQ8 A;  3HO8 A;  4BCI B;  1OI9 B;  1GH6 B;  1XO2 A;  3G33 B;  3WVE B;  2F2C A;  4UN0 A;  3DL1 A;  2LW4 A;  2CCH B;  1N4M A;  1KXU A;  4AKI A;  3X26 B;  4EOI B;  3BLH B;  4EOJ B;  1ZP2 A;  3X28 B;  4CXA B;  2IW6 B;  1QLB A;  1JST B;  2G9X B;  2WEV B;  4JX4 A;  4CRL B;  3F5X B;  4HL4 A;  2ZPE B;  1W98 B;  1AD6 A;  4BCF B;  5CYI B;  4AKH A;  4YOZ A;  4HNU A;  2ZPI B;  3BHU B;  3M03 A;  1VOL A;  3H4C A;  1H27 B;  4FX3 B;  4F6W B;  2V22 B;  2ZPH B;  3QZ9 B;  1TD6 A;  2C4G B;  4JX6 A;  5IHY A;  3QYE A;  4KRD B;  4MIM A;  4F6U B;  3O0G D;  1JOW A;  4FM4 B;  5CEI B;  2DME A;  4BCQ D;  4EOR B;  1D3U B;  3A8H B;  2CYZ B;  1H1Q B;  1JSU B;  4CFM B;  2W96 A;  4ROD A;  4CFU D;  1UGS B;  4ELJ A;  2QF7 A;  3QYB A;  2ZCF B;  1H26 B;  4F7L B;  2X1N B;  4ELL A;  1TFB A;  2QGS A;  4AI6 A;  2CZ7 B;  3QHR B;  3NDQ A;  2PMI B;  5IDN B;  3QXE B;  3MIA B;  4I3Z B;  5DQV A;  2CZ1 B;  2DD4 B;  2WMA B;  1P5E B;  3BG9 A;  1H1R B;  4F6S B;  3WVD B;  1UNL D;  4BCH B;  4ZGJ B;  1OL1 B;  3X24 B;  2DXC B;  4CFW B;  3MY1 B;  2ZPG B;  5BNJ B;  1OIY B;  3TNH B;  1JKW A;  3HZJ A;  3VYG B;  2C6T B;  4EOM B;  4AKG A;  4OB2 B;  5HBJ B;  1F5Q B;  3X20 B;  1VIN A;  3A8M B;  4YOO A;  4BCG B;  2BS3 A;  1C9B A;  3A8O B;  1H24 B;  3A8L B;  4BCO B;  4BXX X;  3PO3 S;  5HBE B;  4M6V A;  5ACB A;  2IVX A;  3MY5 B;  1VYW B;  4MFD A;  1O9K A;  4F7S B;  4Y72 B;  2UUE B;  1UGR B;  3VYH B;  1H25 B;  2ZPB B;  4F70 B;  4OB0 B;  4EC9 B;  3BHT B;  3HHT B;  3BG5 A;  4OB1 B;  4EOK B;  2ZPF B;  1UNH D;  3QYH B;  4LOC A;  2UZL B;  2W9F A;  5EJC A;  2WPA B;  2PK9 B;  3K7A M;  4YC3 B;  3GTM S;  2PHG A;  5HBH B;  1E9H B;  4ROE A;  4G6L B;  4BCN D;  5DQW A;  1OIU B;  1GUX A;  2IW9 B;  4EON B;  5L2W B;  2DD5 B;  3TW7 A;  1AIS B;  1H1S B;  4BBS M;  3RGF B;  1PKD B;  2I40 B;  4EOP B;  4EOQ B;  3VKG A;  1UGQ B;  1IRE B;  1H1P B;  3DOG B;  1FIN B;  4BCQ B;  4EOS B;  1QMZ B;  2QDJ A;  4NC6 A;  4BCM D;  2CZ0 B;  3EJ1 B;  3BG3 A;  2PK2 A;  2D0Q B;  4EOO B;  2PJQ A;  2W99 A;  4JX5 A;  3TNI B;  2C5X B;  1H4L D;  2QDY B;  3BHV B;  5LMK B;  1GY3 B;  4HNV A;  1OGU B;  5ICP B;  1ENW A;  3EOC B;  2C5O B;  4BY7 X;  1OKV B;  3BLQ B;  2BS2 A;  2DPP B;  2R7G A;  3VKH A;  4EOL B;  2C5V B;  2JGZ B;  2W2H A;  4MFE A;  1V29 B;  3QZ5 B;  3X25 B; 
#chains in the Genus database with same CATH homology
 2PK9 B;  1OKW B;  3K7A M;  4YC3 B;  2PHG A;  5HBH B;  4ELJ A;  1E9H B;  4ROE A;  2WIP B;  1G3N C;  4G6L B;  2EUF A;  4BCN D;  2UZE B;  1H26 B;  2WFY B;  5HQ0 B;  4F7L B;  2X1N B;  1FVV B;  1O9K B;  4OGR B;  5LQF B;  3POM A;  4BCJ B;  3LQ5 B;  4ELL A;  1TFB A;  2B9R A;  1OIU B;  2WXV B;  4CFV B;  4CFN B;  1OL2 B;  1GUX A;  2IW9 B;  3DDP B;  2CCI B;  3QHR B;  4EON B;  2PMI B;  4ROC A;  4CFX B;  5IDN B;  3DDQ B;  2IW8 B;  3MIA B;  4BCM B;  4I3Z B;  4F7N B;  5L2W B;  3MI9 B;  4EC8 B;  5I5Z B;  1UNG D;  4F7J B;  4BCK B;  4IMY B;  2WHB B;  2WMA B;  1P5E B;  1AIS B;  1H1S B;  4BCI B;  3RGF B;  1H1R B;  4F6S B;  1UNL D;  1OI9 B;  1PKD B;  4BCH B;  1GH6 B;  2I40 B;  1URC B;  1XO2 A;  1OL1 B;  3G33 B;  4BCP B;  3TNW B;  2F2C A;  4UN0 A;  4EOP B;  4CFW B;  3MY1 B;  2CCH B;  1N4M A;  1KXU A;  4EOQ B;  1H1P B;  4EOI B;  4NST B;  1OIY B;  3BLH B;  3DOG B;  5BNJ B;  4KRC B;  2WIH B;  1ZP2 A;  3TNH B;  2BPM B;  4EOJ B;  4CXA B;  1GUX B;  2IW6 B;  1JKW A;  4TTH A;  1FIN B;  3TN8 B;  2C5N B;  1JST B;  4BCQ B;  2G9X B;  2WEV B;  4II5 B;  4EOS B;  3QHW B;  4CRL B;  1QMZ B;  2QDJ A;  2C6T B;  4BCM D;  3EJ1 B;  4EOM B;  3F5X B;  2UZB B;  5HNB B;  2PK2 A;  5HBJ B;  1F5Q B;  1VIN A;  4YOO A;  4BCG B;  1W98 B;  4EOO B;  1AD6 A;  4OR5 B;  1C9B A;  2I53 A;  4BCF B;  1H24 B;  5CYI B;  4BCO B;  4YOZ A;  2W99 A;  3TNI B;  3BHU B;  3M03 A;  1VOL A;  2C5X B;  3H4C A;  1H4L D;  1H27 B;  4FX3 B;  4F6W B;  2V22 B;  5HBE B;  3BHV B;  5ACB A;  5LMK B;  2IVX A;  2C4G B;  3MY5 B;  1GY3 B;  2BKZ B;  4BCN B;  1VYW B;  3EID B;  3BLR B;  4KRD B;  1O9K A;  4F7S B;  5HVY B;  4F6U B;  3O0G D;  4Y72 B;  1JOW A;  5IF1 B;  2UUE B;  4YOS A;  5IDP B;  5CEI B;  1OGU B;  1H25 B;  4BCQ D;  4EOR B;  5ICP B;  3EOC B;  4F70 B;  2UZD B;  4EC9 B;  1D3U B;  3BHT B;  2C5O B;  5EFQ B;  1OKV B;  3BLQ B;  2W9Z A;  5FGK B;  1H1Q B;  4EOK B;  1UNH D;  1JSU B;  4CFU B;  2WMB B;  1H28 B;  2CJM B;  2UZL B;  4CFM B;  2R7G A;  4EOL B;  2C5V B;  2JGZ B;  2W96 A;  4ROD A;  4CFU D;  2W9F A;  2W2H A;  1BU2 A;  2WPA B;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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