2X3VA

Structure of the f-bar domain of mouse syndapin i
Total Genus 123
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
291
structure length
291
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCNDLMSCVQERAKIEKAYAQQLTDWAKRWRQLIEKGPQYGSLERAWGAMMTEADKVSELHQEVKNSLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEERLAMTREMNSKTEQSVTPEQQKKLVDKVDKCRQDVQKTQEKYEKVLEDVGKTTPQYMEGMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYMHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Molecular Basis for SH3 Domain Regulation of F-Bar-Mediated Membrane Deformation.
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
total genus 123
structure length 291
sequence length 291
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2x3vA01
4WPCA 3HAHA 4FZSA 2EFKA 3HAJA 4NSWA 3LLLA 1URUA 2RAKA 4I1QA 4BNEA 3ACOA 4DCNC 2Q13A 2X3XA 1ZWWA 3QE6A 3CAZA 4AKVA 2ELBA 1I4TA 1I4DA 2YKTA 1X03A 2Z0NA 3G9GA 2FICA 2C08A 1I49A 1I4LA 1X04A 2X3WA 3HAIA 3M3WA 3Q84A 3QNIA 4NQIA 2Z0OA 3ABHA 5C5BA 4DYLA 3OK8A 2RAIA 2D1LA 3SOGA 5C5BB 3I2WA 4ATMA 2D4CA 1Y2OA 2Q12A 2V0OA 3QWEA 3SYVA 4H8SA 4AVMA 4WPEA 3Q0KA 3DYTA 2Z0VA 3PLTA 2X3VA 2RAJA 1WDZA 2EFLA
chains in the Genus database with same CATH superfamily
4NSWA 5TKYA 4R5LA 3BUBA 2Q13A 4PO2A 2WINM 1I4DA 2RT6A 2FICA 4AZGA 2Z0OA 2JNSA 3I2WA 1ZYLA 2V0OA 3BLBA 3DYTA 1WDZA 3DPQA 1W9MA 2OBMA 2X3XA 3BVTA 4AZCB 1SU6A 3DX4A 4AZIA 4R5KA 4DYLA 4JNFA 1SUFA 3D52A 3DX1A 4F01A 4WPEA 1DKZA 2F1BA 1PS3A 2YIBA 3DPPA 3KDRA 2F18A 3QNJA 3BUIA 3D4ZA 4JN4A 2YKTA 2C08A 2YL8A 2X3WA 1R5EA 2F7OA 2F7RA 1Y2OA 2D4CA 3BVUA 2ND0A 2YIAA 1TQSA 3D2FA 2LXYA 1YWMA 1QWNA 3DDGA 4EZYA 3BVWA 2O0I1 4F00A 2ELBA 2ND1A 1JQKA 2WYHA 3ABHA 3T49A 2Q12A 1DKYA 4HY9A 3CZSA 1O7DC 3QA8A 3PLTA 2YLLA 4WPCA 3T48A 1R34A 1OAOA 3ER8C 1MJGA 3EJQA 4JWIA 3ER9B 2GAFD 2GF4A 4FM3A 3CVRA 3SYVA 2YL9A 3OHXM 3HAJA 4EZQA 4D8JA 2F7QA 3I01A 3T4AG 3B52X 2ALWA 4AKVA 1I4LA 1U00A 4NQIA 1TQWA 2RAIA 3T46A 5C5BB 4ATMA 1TQTA 4H8SA 3F7WA 2EX3B 4JL9A 3RV0A 4FZPA 2NCZA 4KIKA 1O7DB 1E2UA 4AZ6A 1HTYA 3D2EA 3DX3A 2Z0VA 3LMFA 3EJTA 1R33A 4EZVA 4IWQA 3KAVA 4JWEA 2PY6A 2GA9D 1GNTA 1X04A 2YL5A 4AZHA 2JNKA 1GNLA 3SOGA 4EZZA 3QWEA 2EFLA 1OA0A 4FZSA 4H6IA 4IWPA 4EZTA 4FZOA 2YLAA 3ACOA 3EJPA 3QE6A 5KBPA 3VKHA 3DDFA 2Z0NA 1E9VA 3M3WA 4H6HA 3BUQA 3BUPA 3O3MB 3KAWA 4AVMA 4AZ7A 4JWCA 4IM3A 2EFKA 4IM0A 1QWUA 3A98A 3B53X 3CZNA 1I4TA 3Q84A 2D1LA 1DKXA 1SU7A 4HR1A 1LQ7A 2QXLA 4G6QA 1URUA 2RAKA 2PMRA 2OBLA 4DCNC 3BUDA 3EJSA 3O3OB 4JNEA 2YL6A 3CKDA 3G9GA 4JWDA 5C5BA 4EZOA 3D51A 3L3OM 3BVXA 3RPMA 2X3VA 2RAJA 2EWFA 3HAHA 3BVVA 3T47A 4AZBA 4EZUA 2F1AA 4I1QA 3DX0A 3ERCC 1ZWWA 4AZCA 4E81A 2YI9A 2KHOA 5E84A 3FD9A 3ZEDA 3O3NB 3LVTA 4B9QA 4E3CA 2OW6A 2N3KA 5FIGA 4EZWA 4AZ5A 4KIKB 4IWOA 3L3PA 1E1DA 4EZSA 4HYBA 2MI7A 4UDYX 3CAZA 3RV1A 3D4YA 4EZNA 3HAIA 3QNIA 4NPHA 2WYIA 3OK8A 2F7PA 3DX2A 4EZRA 1SU8A 1GN9A 2QFFA 2QKWA 3LLLA 3VEBA 1TQUA 3OWGA 2LM0A 4JLCA 2Z8YA 2OO2A 3D50A 3B51X 3GI7A 3UITA 3I39X 2YI8A 1HWWA 4IW0A 3C7NA 3EJRA 4BNEA 1TQVA 4IM2A 3DPOA 2ZXQA 1I49A 1UPXA 2X5CA 2OZNB 4R5IA 3CV5A 5FLEX 4R5GA 2OW7A 4R5JA 4EZPA 3VEAA 4UDXX 4EZXA 4M0MA 2FYVA 1X03A 3EJUA 3I04A 2YIVX 1QX1A 3Q0KA 1OA1A 1HXKA 4HR1B
chains in the Genus database with same CATH topology
4WPCA 3HAHA 4FZSA 2EFKA 3HAJA 4NSWA 3LLLA 1URUA 2RAKA 4I1QA 4BNEA 3ACOA 4DCNC 2Q13A 2X3XA 1ZWWA 3QE6A 3CAZA 4AKVA 2ELBA 1I4TA 1I4DA 2YKTA 1X03A 2Z0NA 3G9GA 2FICA 2C08A 1I49A 1I4LA 1X04A 2X3WA 3HAIA 3M3WA 3Q84A 3QNIA 4NQIA 2Z0OA 3ABHA 5C5BA 4DYLA 3OK8A 2RAIA 2D1LA 3SOGA 5C5BB 3I2WA 4ATMA 2D4CA 1Y2OA 2Q12A 2V0OA 3QWEA 3SYVA 4H8SA 4AVMA 4WPEA 3Q0KA 3DYTA 2Z0VA 3PLTA 2X3VA 2RAJA 1WDZA 2EFLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WPC A;  3HAH A;  4FZS A;  2EFK A;  3HAJ A;  4NSW A;  3LLL A;  1URU A;  2RAK A;  4I1Q A;  4BNE A;  3ACO A;  4DCN C;  2Q13 A;  2X3X A;  1ZWW A;  3QE6 A;  3CAZ A;  4AKV A;  2ELB A;  1I4T A;  1I4D A;  2YKT A;  1X03 A;  2Z0N A;  3G9G A;  2FIC A;  2C08 A;  1I49 A;  1I4L A;  1X04 A;  2X3W A;  3HAI A;  3M3W A;  3Q84 A;  3QNI A;  4NQI A;  2Z0O A;  3ABH A;  5C5B A;  4DYL A;  3OK8 A;  2RAI A;  2D1L A;  3SOG A;  5C5B B;  3I2W A;  4ATM A;  2D4C A;  1Y2O A;  2Q12 A;  2V0O A;  3QWE A;  3SYV A;  4H8S A;  4AVM A;  4WPE A;  3Q0K A;  3DYT A;  2Z0V A;  3PLT A;  2X3V A;  2RAJ A;  1WDZ A;  2EFL A; 
#chains in the Genus database with same CATH topology
 4NSW A;  5TKY A;  4R5L A;  3BUB A;  2Q13 A;  4PO2 A;  2WIN M;  1I4D A;  2RT6 A;  2FIC A;  4AZG A;  2Z0O A;  2JNS A;  3I2W A;  1ZYL A;  2V0O A;  3BLB A;  3DYT A;  1WDZ A;  3DPQ A;  1W9M A;  2OBM A;  2X3X A;  3BVT A;  4AZC B;  1SU6 A;  3DX4 A;  4AZI A;  4R5K A;  4DYL A;  4JNF A;  1SUF A;  3D52 A;  3DX1 A;  4F01 A;  4WPE A;  1DKZ A;  2F1B A;  1PS3 A;  2YIB A;  3DPP A;  3KDR A;  2F18 A;  3QNJ A;  3BUI A;  3D4Z A;  4JN4 A;  2YKT A;  2C08 A;  2YL8 A;  2X3W A;  1R5E A;  2F7O A;  2F7R A;  1Y2O A;  2D4C A;  3BVU A;  2ND0 A;  2YIA A;  1TQS A;  3D2F A;  2LXY A;  1YWM A;  1QWN A;  3DDG A;  4EZY A;  3BVW A;  2O0I 1;  4F00 A;  2ELB A;  2ND1 A;  1JQK A;  2WYH A;  3ABH A;  3T49 A;  2Q12 A;  1DKY A;  4HY9 A;  3CZS A;  1O7D C;  3QA8 A;  3PLT A;  2YLL A;  4WPC A;  3T48 A;  1R34 A;  1OAO A;  3ER8 C;  1MJG A;  3EJQ A;  4JWI A;  3ER9 B;  2GAF D;  2GF4 A;  4FM3 A;  3CVR A;  3SYV A;  2YL9 A;  3OHX M;  3HAJ A;  4EZQ A;  4D8J A;  2F7Q A;  3I01 A;  3T4A G;  3B52 X;  2ALW A;  4AKV A;  1I4L A;  1U00 A;  4NQI A;  1TQW A;  2RAI A;  3T46 A;  5C5B B;  4ATM A;  1TQT A;  4H8S A;  3F7W A;  2EX3 B;  4JL9 A;  3RV0 A;  4FZP A;  2NCZ A;  4KIK A;  1O7D B;  1E2U A;  4AZ6 A;  1HTY A;  3D2E A;  3DX3 A;  2Z0V A;  3LMF A;  3EJT A;  1R33 A;  4EZV A;  4IWQ A;  3KAV A;  4JWE A;  2PY6 A;  2GA9 D;  1GNT A;  1X04 A;  2YL5 A;  4AZH A;  2JNK A;  1GNL A;  3SOG A;  4EZZ A;  3QWE A;  2EFL A;  1OA0 A;  4FZS A;  4H6I A;  4IWP A;  4EZT A;  4FZO A;  2YLA A;  3ACO A;  3EJP A;  3QE6 A;  5KBP A;  3VKH A;  3DDF A;  2Z0N A;  1E9V A;  3M3W A;  4H6H A;  3BUQ A;  3BUP A;  3O3M B;  3KAW A;  4AVM A;  4AZ7 A;  4JWC A;  4IM3 A;  2EFK A;  4IM0 A;  1QWU A;  3A98 A;  3B53 X;  3CZN A;  1I4T A;  3Q84 A;  2D1L A;  1DKX A;  1SU7 A;  4HR1 A;  1LQ7 A;  2QXL A;  4G6Q A;  1URU A;  2RAK A;  2PMR A;  2OBL A;  4DCN C;  3BUD A;  3EJS A;  3O3O B;  4JNE A;  2YL6 A;  3CKD A;  3G9G A;  4JWD A;  5C5B A;  4EZO A;  3D51 A;  3L3O M;  3BVX A;  3RPM A;  2X3V A;  2RAJ A;  2EWF A;  3HAH A;  3BVV A;  3T47 A;  4AZB A;  4EZU A;  2F1A A;  4I1Q A;  3DX0 A;  3ERC C;  1ZWW A;  4AZC A;  4E81 A;  2YI9 A;  2KHO A;  5E84 A;  3FD9 A;  3ZED A;  3O3N B;  3LVT A;  4B9Q A;  4E3C A;  2OW6 A;  2N3K A;  5FIG A;  4EZW A;  4AZ5 A;  4KIK B;  4IWO A;  3L3P A;  1E1D A;  4EZS A;  4HYB A;  2MI7 A;  4UDY X;  3CAZ A;  3RV1 A;  3D4Y A;  4EZN A;  3HAI A;  3QNI A;  4NPH A;  2WYI A;  3OK8 A;  2F7P A;  3DX2 A;  4EZR A;  1SU8 A;  1GN9 A;  2QFF A;  2QKW A;  3LLL A;  3VEB A;  1TQU A;  3OWG A;  2LM0 A;  4JLC A;  2Z8Y A;  2OO2 A;  3D50 A;  3B51 X;  3GI7 A;  3UIT A;  3I39 X;  2YI8 A;  1HWW A;  4IW0 A;  3C7N A;  3EJR A;  4BNE A;  1TQV A;  4IM2 A;  3DPO A;  2ZXQ A;  1I49 A;  1UPX A;  2X5C A;  2OZN B;  4R5I A;  3CV5 A;  5FLE X;  4R5G A;  2OW7 A;  4R5J A;  4EZP A;  3VEA A;  4UDX X;  4EZX A;  4M0M A;  2FYV A;  1X03 A;  3EJU A;  3I04 A;  2YIV X;  1QX1 A;  3Q0K A;  1OA1 A;  1HXK A;  4HR1 B; 
#chains in the Genus database with same CATH homology
 4WPC A;  3HAH A;  4FZS A;  2EFK A;  3HAJ A;  4NSW A;  3LLL A;  1URU A;  2RAK A;  4I1Q A;  4BNE A;  3ACO A;  4DCN C;  2Q13 A;  2X3X A;  1ZWW A;  3QE6 A;  3CAZ A;  4AKV A;  2ELB A;  1I4T A;  1I4D A;  2YKT A;  1X03 A;  2Z0N A;  3G9G A;  2FIC A;  2C08 A;  1I49 A;  1I4L A;  1X04 A;  2X3W A;  3HAI A;  3M3W A;  3Q84 A;  3QNI A;  4NQI A;  2Z0O A;  3ABH A;  5C5B A;  4DYL A;  3OK8 A;  2RAI A;  2D1L A;  3SOG A;  5C5B B;  3I2W A;  4ATM A;  2D4C A;  1Y2O A;  2Q12 A;  2V0O A;  3QWE A;  3SYV A;  4H8S A;  4AVM A;  4WPE A;  3Q0K A;  3DYT A;  2Z0V A;  3PLT A;  2X3V A;  2RAJ A;  1WDZ A;  2EFL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...