2X3VA

Structure of the f-bar domain of mouse syndapin i
Total Genus 123
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
291
structure length
291
Chain Sequence
DSFWEVGNYKRTVKRIDDGHRLCNDLMSCVQERAKIEKAYAQQLTDWAKRWRQLIEKGPQYGSLERAWGAMMTEADKVSELHQEVKNSLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEERLAMTREMNSKTEQSVTPEQQKKLVDKVDKCRQDVQKTQEKYEKVLEDVGKTTPQYMEGMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYMHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis for SH3 Domain Regulation of F-Bar-Mediated Membrane Deformation.
pubmed doi rcsb
molecule tags Endocytosis
source organism Mus musculus
molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
total genus 123
structure length 291
sequence length 291
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2010-01-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2x3vA01
3Q84A 3DYTA 4DCNC 3HAJA 4DYLA 3ACOA 3G9GA 4WPCA 1Y2OA 2D4CA 2X3WA 4H8SA 2RAIA 2D1LA 1WDZA 3QWEA 5C5BB 1ZWWA 3OK8A 5C5BA 3I2WA 2RAKA 3QE6A 2X3XA 2YKTA 3ABHA 2C08A 2EFLA 3HAIA 2Q12A 2V0OA 4AKVA 3Q0KA 3SYVA 1I49A 1I4LA 2RAJA 2ELBA 2EFKA 2FICA 4I1QA 4NSWA 4AVMA 1I4TA 2Z0VA 3QNIA 4NQIA 4FZSA 2Z0NA 3PLTA 1X03A 3HAHA 4ATMA 1X04A 1URUA 3SOGA 1I4DA 3CAZA 2X3VA 4WPEA 2Q13A 3LLLA 3M3WA 2Z0OA 4BNEA
chains in the Genus database with same CATH superfamily
4EZUA 1HXKA 3KDRA 2OBLA 2EWFA 3DX4A 4IWQA 4KIKA 4E81A 4AVMA 2FICA 2Z8YA 3D2EA 3BUQA 2YIBA 1OAOA 2OBMA 2RT6A 2GAFD 1DKXA 2D4CA 1SUFA 4JWCA 3VKHA 3SYVA 1SU8A 2YLAA 2LM0A 4EZOA 1E2UA 3UITA 3SOGA 1QWUA 3M3WA 2F18A 3BVVA 4DYLA 2YI8A 4HR1B 1YWMA 3KAVA 3BLBA 2F7QA 4EZQA 4E3CA 1R34A 2NCZA 4NPHA 4IWOA 2YIAA 4IW0A 2YL6A 4D8JA 4EZNA 3A98A 3GI7A 2WYIA 2D1LA 2KHOA 4AZCB 3BVWA 2F1BA 2QFFA 1LQ7A 3I2WA 4B9QA 3T48A 4KIKB 2QXLA 1I4LA 3O3OB 2YIVX 3DX0A 3T47A 1QWNA 2YL8A 3OHXM 2OW6A 2F1AA 4EZXA 3OK8A 3QE6A 1OA1A 4JWDA 3CVRA 1GNTA 2ZXQA 3QA8A 1X03A 3VEBA 1I4DA 2X3VA 2Q13A 3DPQA 1QX1A 1GN9A 3B51X 1UPXA 3DPPA 3BUDA 3L3PA 2X5CA 1TQTA 4AZCA 4R5JA 4UDYX 3LMFA 2ND1A 5E84A 3ERCC 3DX2A 4I1QA 1I49A 4EZRA 4IM2A 3C7NA 3EJQA 4AZGA 2YLLA 3Q84A 5KBPA 3ER8C 3B53X 3QWEA 2YI9A 2X3XA 2YKTA 1W9MA 4AZ7A 3QNIA 1GNLA 4NQIA 1TQWA 3O3NB 1PS3A 2F7OA 1R5EA 4F00A 3G9GA 3EJRA 4JNFA 3D4ZA 5FIGA 3BVTA 1ZWWA 1TQSA 3EJUA 1ZYLA 4R5KA 2Q12A 2OZNB 3BVXA 4JNEA 3D4YA 2ALWA 1HWWA 3L3OM 4H8SA 2WINM 2RAIA 1WDZA 2EX3B 5C5BA 4AZHA 3RV0A 4EZSA 2JNSA 4NSWA 3F7WA 3DDFA 3CAZA 4EZTA 3CZNA 3BVUA 4UDXX 4R5LA 3EJPA 2GF4A 2RAKA 3FD9A 2ND0A 4AZ5A 1SU7A 2Z0VA 4JWIA 4EZPA 4ATMA 4WPEA 4EZYA 4BNEA 3ZEDA 4DCNC 1JQKA 4FZOA 3BUIA 1DKZA 4F01A 3DPOA 3HAIA 4G6QA 3Q0KA 2O0I1 2OO2A 1E9VA 2LXYA 4IM3A 4H6HA 3EJSA 1R33A 2F7PA 2PMRA 1MJGA 3D51A 3BUBA 3CZSA 3LVTA 1Y2OA 2X3WA 2N3KA 5C5BB 4AZBA 3RV1A 3KAWA 1TQUA 4AKVA 1O7DB 1I4TA 4EZVA 1X04A 4H6IA 4HY9A 1DKYA 3ER9B 1OA0A 5TKYA 3T4AG 4IM0A 4R5IA 4FM3A 2PY6A 4EZWA 2Z0NA 2QKWA 1URUA 4JN4A 3LLLA 3DYTA 3QNJA 3BUPA 3EJTA 4EZZA 4WPCA 3D50A 3RPMA 3DX3A 4JWEA 1HTYA 2OW7A 1U00A 2JNKA 2V0OA 2RAJA 2MI7A 2ELBA 2FYVA 3I01A 2GA9D 4AZ6A 2YL9A 3PLTA 2Z0OA 3HAJA 3B52X 2F7RA 1TQVA 3DX1A 3T46A 1SU6A 3D2FA 3DDGA 4R5GA 3HAHA 1O7DC 4HYBA 3OWGA 4FZPA 3ACOA 1E1DA 3CV5A 4PO2A 4HR1A 4JL9A 3O3MB 2YL5A 3CKDA 3D52A 3ABHA 2C08A 2EFLA 2WYHA 4M0MA 4AZIA 2EFKA 3I39X 4JLCA 4FZSA 3T49A 5FLEX 3VEAA 3I04A 4IWPA
chains in the Genus database with same CATH topology
3Q84A 3DYTA 4DCNC 3HAJA 4DYLA 3ACOA 3G9GA 4WPCA 1Y2OA 2D4CA 2X3WA 4H8SA 2RAIA 2D1LA 1WDZA 3QWEA 5C5BB 1ZWWA 3OK8A 5C5BA 3I2WA 2RAKA 3QE6A 2X3XA 2YKTA 3ABHA 2C08A 2EFLA 3HAIA 2Q12A 2V0OA 4AKVA 3Q0KA 3SYVA 1I49A 1I4LA 2RAJA 2ELBA 2EFKA 2FICA 4I1QA 4NSWA 4AVMA 1I4TA 2Z0VA 3QNIA 4NQIA 4FZSA 2Z0NA 3PLTA 1X03A 3HAHA 4ATMA 1X04A 1URUA 3SOGA 1I4DA 3CAZA 2X3VA 4WPEA 2Q13A 3LLLA 3M3WA 2Z0OA 4BNEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q84 A;  3DYT A;  4DCN C;  3HAJ A;  4DYL A;  3ACO A;  3G9G A;  4WPC A;  1Y2O A;  2D4C A;  2X3W A;  4H8S A;  2RAI A;  2D1L A;  1WDZ A;  3QWE A;  5C5B B;  1ZWW A;  3OK8 A;  5C5B A;  3I2W A;  2RAK A;  3QE6 A;  2X3X A;  2YKT A;  3ABH A;  2C08 A;  2EFL A;  3HAI A;  2Q12 A;  2V0O A;  4AKV A;  3Q0K A;  3SYV A;  1I49 A;  1I4L A;  2RAJ A;  2ELB A;  2EFK A;  2FIC A;  4I1Q A;  4NSW A;  4AVM A;  1I4T A;  2Z0V A;  3QNI A;  4NQI A;  4FZS A;  2Z0N A;  3PLT A;  1X03 A;  3HAH A;  4ATM A;  1X04 A;  1URU A;  3SOG A;  1I4D A;  3CAZ A;  2X3V A;  4WPE A;  2Q13 A;  3LLL A;  3M3W A;  2Z0O A;  4BNE A; 
#chains in the Genus database with same CATH topology
 4EZU A;  1HXK A;  3KDR A;  2OBL A;  2EWF A;  3DX4 A;  4IWQ A;  4KIK A;  4E81 A;  4AVM A;  2FIC A;  2Z8Y A;  3D2E A;  3BUQ A;  2YIB A;  1OAO A;  2OBM A;  2RT6 A;  2GAF D;  1DKX A;  2D4C A;  1SUF A;  4JWC A;  3VKH A;  3SYV A;  1SU8 A;  2YLA A;  2LM0 A;  4EZO A;  1E2U A;  3UIT A;  3SOG A;  1QWU A;  3M3W A;  2F18 A;  3BVV A;  4DYL A;  2YI8 A;  4HR1 B;  1YWM A;  3KAV A;  3BLB A;  2F7Q A;  4EZQ A;  4E3C A;  1R34 A;  2NCZ A;  4NPH A;  4IWO A;  2YIA A;  4IW0 A;  2YL6 A;  4D8J A;  4EZN A;  3A98 A;  3GI7 A;  2WYI A;  2D1L A;  2KHO A;  4AZC B;  3BVW A;  2F1B A;  2QFF A;  1LQ7 A;  3I2W A;  4B9Q A;  3T48 A;  4KIK B;  2QXL A;  1I4L A;  3O3O B;  2YIV X;  3DX0 A;  3T47 A;  1QWN A;  2YL8 A;  3OHX M;  2OW6 A;  2F1A A;  4EZX A;  3OK8 A;  3QE6 A;  1OA1 A;  4JWD A;  3CVR A;  1GNT A;  2ZXQ A;  3QA8 A;  1X03 A;  3VEB A;  1I4D A;  2X3V A;  2Q13 A;  3DPQ A;  1QX1 A;  1GN9 A;  3B51 X;  1UPX A;  3DPP A;  3BUD A;  3L3P A;  2X5C A;  1TQT A;  4AZC A;  4R5J A;  4UDY X;  3LMF A;  2ND1 A;  5E84 A;  3ERC C;  3DX2 A;  4I1Q A;  1I49 A;  4EZR A;  4IM2 A;  3C7N A;  3EJQ A;  4AZG A;  2YLL A;  3Q84 A;  5KBP A;  3ER8 C;  3B53 X;  3QWE A;  2YI9 A;  2X3X A;  2YKT A;  1W9M A;  4AZ7 A;  3QNI A;  1GNL A;  4NQI A;  1TQW A;  3O3N B;  1PS3 A;  2F7O A;  1R5E A;  4F00 A;  3G9G A;  3EJR A;  4JNF A;  3D4Z A;  5FIG A;  3BVT A;  1ZWW A;  1TQS A;  3EJU A;  1ZYL A;  4R5K A;  2Q12 A;  2OZN B;  3BVX A;  4JNE A;  3D4Y A;  2ALW A;  1HWW A;  3L3O M;  4H8S A;  2WIN M;  2RAI A;  1WDZ A;  2EX3 B;  5C5B A;  4AZH A;  3RV0 A;  4EZS A;  2JNS A;  4NSW A;  3F7W A;  3DDF A;  3CAZ A;  4EZT A;  3CZN A;  3BVU A;  4UDX X;  4R5L A;  3EJP A;  2GF4 A;  2RAK A;  3FD9 A;  2ND0 A;  4AZ5 A;  1SU7 A;  2Z0V A;  4JWI A;  4EZP A;  4ATM A;  4WPE A;  4EZY A;  4BNE A;  3ZED A;  4DCN C;  1JQK A;  4FZO A;  3BUI A;  1DKZ A;  4F01 A;  3DPO A;  3HAI A;  4G6Q A;  3Q0K A;  2O0I 1;  2OO2 A;  1E9V A;  2LXY A;  4IM3 A;  4H6H A;  3EJS A;  1R33 A;  2F7P A;  2PMR A;  1MJG A;  3D51 A;  3BUB A;  3CZS A;  3LVT A;  1Y2O A;  2X3W A;  2N3K A;  5C5B B;  4AZB A;  3RV1 A;  3KAW A;  1TQU A;  4AKV A;  1O7D B;  1I4T A;  4EZV A;  1X04 A;  4H6I A;  4HY9 A;  1DKY A;  3ER9 B;  1OA0 A;  5TKY A;  3T4A G;  4IM0 A;  4R5I A;  4FM3 A;  2PY6 A;  4EZW A;  2Z0N A;  2QKW A;  1URU A;  4JN4 A;  3LLL A;  3DYT A;  3QNJ A;  3BUP A;  3EJT A;  4EZZ A;  4WPC A;  3D50 A;  3RPM A;  3DX3 A;  4JWE A;  1HTY A;  2OW7 A;  1U00 A;  2JNK A;  2V0O A;  2RAJ A;  2MI7 A;  2ELB A;  2FYV A;  3I01 A;  2GA9 D;  4AZ6 A;  2YL9 A;  3PLT A;  2Z0O A;  3HAJ A;  3B52 X;  2F7R A;  1TQV A;  3DX1 A;  3T46 A;  1SU6 A;  3D2F A;  3DDG A;  4R5G A;  3HAH A;  1O7D C;  4HYB A;  3OWG A;  4FZP A;  3ACO A;  1E1D A;  3CV5 A;  4PO2 A;  4HR1 A;  4JL9 A;  3O3M B;  2YL5 A;  3CKD A;  3D52 A;  3ABH A;  2C08 A;  2EFL A;  2WYH A;  4M0M A;  4AZI A;  2EFK A;  3I39 X;  4JLC A;  4FZS A;  3T49 A;  5FLE X;  3VEA A;  3I04 A;  4IWP A; 
#chains in the Genus database with same CATH homology
 3Q84 A;  3DYT A;  4DCN C;  3HAJ A;  4DYL A;  3ACO A;  3G9G A;  4WPC A;  1Y2O A;  2D4C A;  2X3W A;  4H8S A;  2RAI A;  2D1L A;  1WDZ A;  3QWE A;  5C5B B;  1ZWW A;  3OK8 A;  5C5B A;  3I2W A;  2RAK A;  3QE6 A;  2X3X A;  2YKT A;  3ABH A;  2C08 A;  2EFL A;  3HAI A;  2Q12 A;  2V0O A;  4AKV A;  3Q0K A;  3SYV A;  1I49 A;  1I4L A;  2RAJ A;  2ELB A;  2EFK A;  2FIC A;  4I1Q A;  4NSW A;  4AVM A;  1I4T A;  2Z0V A;  3QNI A;  4NQI A;  4FZS A;  2Z0N A;  3PLT A;  1X03 A;  3HAH A;  4ATM A;  1X04 A;  1URU A;  3SOG A;  1I4D A;  3CAZ A;  2X3V A;  4WPE A;  2Q13 A;  3LLL A;  3M3W A;  2Z0O A;  4BNE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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