2C08A

Rat endophilin a1 bar domain
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
204
structure length
204
Chain Sequence
EGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDMEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of Endophilin N-Bar Domain-Mediated Membrane Curvature.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords SH3-CONTAINING GRB2-LIKE PROTEIN 2
total genus 73
structure length 204
sequence length 204
ec nomenclature ec 2.3.1.-:
pdb deposition date 2005-08-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 2c08A00
3ACOA 5C5BB 2YKTA 4WPEA 1I4DA 2X3XA 2EFKA 2C08A 1I4TA 3CAZA 3LLLA 4AKVA 2D1LA 3I2WA 1I49A 2Q12A 2X3VA 1X04A 2V0OA 3OK8A 4NQIA 2RAJA 2Z0VA 4WPCA 3PLTA 3Q84A 4BNEA 5C5BA 3ABHA 1URUA 4DYLA 1X03A 3Q0KA 4DCNC 2ELBA 3QE6A 4I1QA 1WDZA 4AVMA 2FICA 2Q13A 2Z0NA 2D4CA 3HAHA 3M3WA 4ATMA 1I4LA 2RAKA 4NSWA 3G9GA 3SYVA 2RAIA 4H8SA 4FZSA 2X3WA 3DYTA 1ZWWA 3HAJA 2Z0OA 3HAIA 3QWEA 3SOGA 3QNIA 1Y2OA 2EFLA
chains in the Genus database with same CATH superfamily
1GNTA 4B9QA 3D4ZA 4AZHA 2D1LA 1I49A 4JNFA 2QXLA 4KIKB 3OWGA 2RT6A 2Z0VA 4EZVA 2OO2A 1E1DA 2PMRA 1I4LA 2ND0A 2X5CA 3LVTA 4G6QA 2EFLA 2GF4A 4JWEA 4AKVA 1TQVA 3I2WA 2KHOA 3KDRA 1JQKA 3PLTA 4JL9A 4H6IA 4IW0A 3ER9B 3T47A 2YI8A 3SYVA 4E81A 3ACOA 3QNJA 2QFFA 2F18A 1OA0A 2YI9A 1HXKA 3T48A 5C5BA 3Q84A 4JWCA 3ABHA 4IM0A 4AVMA 2OW7A 3BUPA 1DKYA 4R5GA 2YIVX 3D50A 1MJGA 2FYVA 3DDFA 4F01A 3BVTA 1GN9A 2GA9D 2F7QA 3T49A 4R5LA 2RAKA 3ZEDA 4IWPA 3BVUA 3O3OB 4FZOA 1I4DA 3D51A 4UDYX 3BUQA 4D8JA 3I39X 4JNEA 2YL9A 4JWDA 1SU7A 2N3KA 1X03A 4AZ6A 4AZCA 2FICA 3DX2A 3D4YA 3KAVA 3DPPA 4HR1A 4JLCA 3C7NA 4FZSA 1Y2OA 2YL5A 2EFKA 3DX3A 2OBMA 4HYBA 1SUFA 3I04A 5TKYA 2Z0NA 1SU8A 1O7DC 2RAIA 4IWOA 4EZRA 2Z8YA 4R5JA 3HAJA 1E9VA 3SOGA 4JWIA 4EZYA 3T4AG 2YKTA 2ALWA 3BVXA 2WINM 4EZOA 3CAZA 4F00A 1OAOA 4NQIA 3VEAA 2GAFD 4E3CA 2YIBA 2D4CA 3HAHA 3G9GA 2F7OA 3GI7A 4H8SA 3DX0A 5C5BB 3CZSA 2X3XA 3EJQA 2WYIA 3BLBA 2ELBA 4R5IA 1DKZA 1OA1A 4EZZA 4AZBA 4UDXX 3D2FA 3EJRA 3BUBA 3A98A 4IM2A 3O3NB 2EX3B 3BVVA 1DKXA 2O0I1 3KAWA 3OK8A 4WPCA 4BNEA 1GNLA 1TQTA 4EZWA 1TQSA 1HWWA 4EZUA 2YLLA 4PO2A 2OW6A 3EJPA 3DYTA 3EJUA 3QWEA 3CV5A 1R34A 3OHXM 3LLLA 4AZCB 3DX1A 1X04A 2V0OA 4AZIA 4H6HA 4HR1B 1HTYA 4DCNC 3L3PA 3F7WA 1WDZA 4ATMA 3EJSA 1TQWA 2ND1A 4JN4A 1ZWWA 3QNIA 4IWQA 3DPQA 2F1AA 2WYHA 2X3VA 2RAJA 3QA8A 4EZXA 4I1QA 3BUIA 2NCZA 2LXYA 3DX4A 4NSWA 4NPHA 2PY6A 4HY9A 4EZQA 2YIAA 2QKWA 1ZYLA 4EZNA 5FIGA 3UITA 2Q12A 2JNKA 4AZ5A 2YLAA 3DDGA 1QWUA 4KIKA 4FM3A 2F1BA 3ER8C 3D2EA 3CVRA 2YL8A 2ZXQA 2OBLA 3FD9A 4EZPA 3B53X 3BVWA 3B52X 1LQ7A 4AZ7A 4DYLA 1QX1A 3RPMA 1PS3A 2OZNB 4EZTA 5E84A 5KBPA 5FLEX 4WPEA 3CKDA 3BUDA 1R5EA 2C08A 1UPXA 2F7PA 1YWMA 3I01A 3EJTA 2JNSA 2Q13A 3D52A 3CZNA 3ERCC 3B51X 1R33A 2EWFA 4IM3A 1I4TA 2LM0A 1E2UA 3DPOA 3O3MB 3Q0KA 3RV0A 2F7RA 3M3WA 4EZSA 4FZPA 1O7DB 1QWNA 4AZGA 2Z0OA 3HAIA 2MI7A 4R5KA 3VEBA 1U00A 2YL6A 3L3OM 3LMFA 1SU6A 1TQUA 3VKHA 4M0MA 1URUA 3T46A 3QE6A 1W9MA 2X3WA 3RV1A
chains in the Genus database with same CATH topology
3ACOA 5C5BB 2YKTA 4WPEA 1I4DA 2X3XA 2EFKA 2C08A 1I4TA 3CAZA 3LLLA 4AKVA 2D1LA 3I2WA 1I49A 2Q12A 2X3VA 1X04A 2V0OA 3OK8A 4NQIA 2RAJA 2Z0VA 4WPCA 3PLTA 3Q84A 4BNEA 5C5BA 3ABHA 1URUA 4DYLA 1X03A 3Q0KA 4DCNC 2ELBA 3QE6A 4I1QA 1WDZA 4AVMA 2FICA 2Q13A 2Z0NA 2D4CA 3HAHA 3M3WA 4ATMA 1I4LA 2RAKA 4NSWA 3G9GA 3SYVA 2RAIA 4H8SA 4FZSA 2X3WA 3DYTA 1ZWWA 3HAJA 2Z0OA 3HAIA 3QWEA 3SOGA 3QNIA 1Y2OA 2EFLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ACO A;  5C5B B;  2YKT A;  4WPE A;  1I4D A;  2X3X A;  2EFK A;  2C08 A;  1I4T A;  3CAZ A;  3LLL A;  4AKV A;  2D1L A;  3I2W A;  1I49 A;  2Q12 A;  2X3V A;  1X04 A;  2V0O A;  3OK8 A;  4NQI A;  2RAJ A;  2Z0V A;  4WPC A;  3PLT A;  3Q84 A;  4BNE A;  5C5B A;  3ABH A;  1URU A;  4DYL A;  1X03 A;  3Q0K A;  4DCN C;  2ELB A;  3QE6 A;  4I1Q A;  1WDZ A;  4AVM A;  2FIC A;  2Q13 A;  2Z0N A;  2D4C A;  3HAH A;  3M3W A;  4ATM A;  1I4L A;  2RAK A;  4NSW A;  3G9G A;  3SYV A;  2RAI A;  4H8S A;  4FZS A;  2X3W A;  3DYT A;  1ZWW A;  3HAJ A;  2Z0O A;  3HAI A;  3QWE A;  3SOG A;  3QNI A;  1Y2O A;  2EFL A; 
#chains in the Genus database with same CATH topology
 1GNT A;  4B9Q A;  3D4Z A;  4AZH A;  2D1L A;  1I49 A;  4JNF A;  2QXL A;  4KIK B;  3OWG A;  2RT6 A;  2Z0V A;  4EZV A;  2OO2 A;  1E1D A;  2PMR A;  1I4L A;  2ND0 A;  2X5C A;  3LVT A;  4G6Q A;  2EFL A;  2GF4 A;  4JWE A;  4AKV A;  1TQV A;  3I2W A;  2KHO A;  3KDR A;  1JQK A;  3PLT A;  4JL9 A;  4H6I A;  4IW0 A;  3ER9 B;  3T47 A;  2YI8 A;  3SYV A;  4E81 A;  3ACO A;  3QNJ A;  2QFF A;  2F18 A;  1OA0 A;  2YI9 A;  1HXK A;  3T48 A;  5C5B A;  3Q84 A;  4JWC A;  3ABH A;  4IM0 A;  4AVM A;  2OW7 A;  3BUP A;  1DKY A;  4R5G A;  2YIV X;  3D50 A;  1MJG A;  2FYV A;  3DDF A;  4F01 A;  3BVT A;  1GN9 A;  2GA9 D;  2F7Q A;  3T49 A;  4R5L A;  2RAK A;  3ZED A;  4IWP A;  3BVU A;  3O3O B;  4FZO A;  1I4D A;  3D51 A;  4UDY X;  3BUQ A;  4D8J A;  3I39 X;  4JNE A;  2YL9 A;  4JWD A;  1SU7 A;  2N3K A;  1X03 A;  4AZ6 A;  4AZC A;  2FIC A;  3DX2 A;  3D4Y A;  3KAV A;  3DPP A;  4HR1 A;  4JLC A;  3C7N A;  4FZS A;  1Y2O A;  2YL5 A;  2EFK A;  3DX3 A;  2OBM A;  4HYB A;  1SUF A;  3I04 A;  5TKY A;  2Z0N A;  1SU8 A;  1O7D C;  2RAI A;  4IWO A;  4EZR A;  2Z8Y A;  4R5J A;  3HAJ A;  1E9V A;  3SOG A;  4JWI A;  4EZY A;  3T4A G;  2YKT A;  2ALW A;  3BVX A;  2WIN M;  4EZO A;  3CAZ A;  4F00 A;  1OAO A;  4NQI A;  3VEA A;  2GAF D;  4E3C A;  2YIB A;  2D4C A;  3HAH A;  3G9G A;  2F7O A;  3GI7 A;  4H8S A;  3DX0 A;  5C5B B;  3CZS A;  2X3X A;  3EJQ A;  2WYI A;  3BLB A;  2ELB A;  4R5I A;  1DKZ A;  1OA1 A;  4EZZ A;  4AZB A;  4UDX X;  3D2F A;  3EJR A;  3BUB A;  3A98 A;  4IM2 A;  3O3N B;  2EX3 B;  3BVV A;  1DKX A;  2O0I 1;  3KAW A;  3OK8 A;  4WPC A;  4BNE A;  1GNL A;  1TQT A;  4EZW A;  1TQS A;  1HWW A;  4EZU A;  2YLL A;  4PO2 A;  2OW6 A;  3EJP A;  3DYT A;  3EJU A;  3QWE A;  3CV5 A;  1R34 A;  3OHX M;  3LLL A;  4AZC B;  3DX1 A;  1X04 A;  2V0O A;  4AZI A;  4H6H A;  4HR1 B;  1HTY A;  4DCN C;  3L3P A;  3F7W A;  1WDZ A;  4ATM A;  3EJS A;  1TQW A;  2ND1 A;  4JN4 A;  1ZWW A;  3QNI A;  4IWQ A;  3DPQ A;  2F1A A;  2WYH A;  2X3V A;  2RAJ A;  3QA8 A;  4EZX A;  4I1Q A;  3BUI A;  2NCZ A;  2LXY A;  3DX4 A;  4NSW A;  4NPH A;  2PY6 A;  4HY9 A;  4EZQ A;  2YIA A;  2QKW A;  1ZYL A;  4EZN A;  5FIG A;  3UIT A;  2Q12 A;  2JNK A;  4AZ5 A;  2YLA A;  3DDG A;  1QWU A;  4KIK A;  4FM3 A;  2F1B A;  3ER8 C;  3D2E A;  3CVR A;  2YL8 A;  2ZXQ A;  2OBL A;  3FD9 A;  4EZP A;  3B53 X;  3BVW A;  3B52 X;  1LQ7 A;  4AZ7 A;  4DYL A;  1QX1 A;  3RPM A;  1PS3 A;  2OZN B;  4EZT A;  5E84 A;  5KBP A;  5FLE X;  4WPE A;  3CKD A;  3BUD A;  1R5E A;  2C08 A;  1UPX A;  2F7P A;  1YWM A;  3I01 A;  3EJT A;  2JNS A;  2Q13 A;  3D52 A;  3CZN A;  3ERC C;  3B51 X;  1R33 A;  2EWF A;  4IM3 A;  1I4T A;  2LM0 A;  1E2U A;  3DPO A;  3O3M B;  3Q0K A;  3RV0 A;  2F7R A;  3M3W A;  4EZS A;  4FZP A;  1O7D B;  1QWN A;  4AZG A;  2Z0O A;  3HAI A;  2MI7 A;  4R5K A;  3VEB A;  1U00 A;  2YL6 A;  3L3O M;  3LMF A;  1SU6 A;  1TQU A;  3VKH A;  4M0M A;  1URU A;  3T46 A;  3QE6 A;  1W9M A;  2X3W A;  3RV1 A; 
#chains in the Genus database with same CATH homology
 3ACO A;  5C5B B;  2YKT A;  4WPE A;  1I4D A;  2X3X A;  2EFK A;  2C08 A;  1I4T A;  3CAZ A;  3LLL A;  4AKV A;  2D1L A;  3I2W A;  1I49 A;  2Q12 A;  2X3V A;  1X04 A;  2V0O A;  3OK8 A;  4NQI A;  2RAJ A;  2Z0V A;  4WPC A;  3PLT A;  3Q84 A;  4BNE A;  5C5B A;  3ABH A;  1URU A;  4DYL A;  1X03 A;  3Q0K A;  4DCN C;  2ELB A;  3QE6 A;  4I1Q A;  1WDZ A;  4AVM A;  2FIC A;  2Q13 A;  2Z0N A;  2D4C A;  3HAH A;  3M3W A;  4ATM A;  1I4L A;  2RAK A;  4NSW A;  3G9G A;  3SYV A;  2RAI A;  4H8S A;  4FZS A;  2X3W A;  3DYT A;  1ZWW A;  3HAJ A;  2Z0O A;  3HAI A;  3QWE A;  3SOG A;  3QNI A;  1Y2O A;  2EFL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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