2DXBB

Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
pubmed doi rcsb
molecule tags Hydrolase
source organism Thiobacillus thioparus
molecule keywords Thiocyanate hydrolase subunit alpha
total genus 46
structure length 152
sequence length 152
chains with identical sequence E, H, K, N, Q, T, W
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2006-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2dxbB00
2CZ1B 2DXCB 3QXEB 2DXBB 1UGQB 1AHJB 4ZGEB 4OB2B 3X20B 3HHTB 3X26B 2CZ7B 2CYZB 3QYHB 4ZGJB 3VYHB 2ZPEB 4OB0B 3A8GB 3A8OB 1UGPB 2DD5B 3VYGB 4ZGDB 2ZPBB 1UGRB 2D0QB 2ZZDB 2ZCFB 3A8MB 3A8LB 2AHJB 2CZ6B 3X28B 2DD4B 2ZPGB 1IREB 3QYGB 1UGSB 2ZPIB 2DPPB 2QDYB 2ZPHB 3QZ9B 4FM4B 3WVEB 3WVDB 3X25B 2ZPFB 3QZ5B 1V29B 3A8HB 4OB1B 2CZ0B 4OB3B 3X24B
chains in the Genus database with same CATH superfamily
3QXEB 3BLHB 2PJQA 4CFMB 3DJBA 1UNGD 5IF1B 2CZ6B 2C6TB 3RGFB 2IVXA 1JSUB 4EOIB 4F6UB 4BBRM 3X24B 2WIPB 5HVYB 3DL1A 5HBHB 5ICPB 4F70B 3X28B 4EOQB 2UZBB 4HNUA 3VKHA 4CRLB 4HNVA 5DQWA 1ENWA 2R7GA 2KR6A 1O9KB 4BCJB 1QMZB 1PKDB 4ZGEB 4BCOB 2X1NB 2DMEA 2UZDB 2DD5B 1OIYB 3TNHB 2C5OB 4JX4A 1H1PB 4BY7X 1OI9B 2C5VB 2CZ0B 2KMGA 3QHRB 2QFZA 4EOOB 4EC8B 5HNBB 1UNHD 5IHYA 2ZPBB 3EIDB 3O0GD 3HB9A 5HBEB 1AISB 1GUXA 5IDNB 4MFDA 2W2HA 4EOJB 2DXBB 1JKWA 2WPAB 2CZ7B 2WHBB 2PMIB 1UGRB 2CCHB 2B9RA 4EOSB 1IREB 1F5QB 1VOLA 4EOPB 4EC9B 4MFEA 3G33B 1AHJB 3X20B 5EFQB 2BKZB 2CYZB 3MIAB 3VYHB 2ZPEB 1JSTB 4RODA 3MI9B 1GH6B 4JX5A 3A8LB 2W9FA 4BCGB 2QF7A 3BG9A 3X25B 2ZPFB 4OB3B 5EJCA 3B57A 2V22B 3TNIB 4OB0B 4AI6A 2QQ8A 2QDJA 4F6WB 4BCQB 1TFBA 1UGSB 1D3UB 5CYIB 1V29B 4Y72B 1XO2A 4EONB 4F7JB 4BCPB 4AKIA 2BPMB 3HO8A 3VYGB 1OGUB 4KRCB 4ZGDB 1OKVB 4BCIB 2AHJB 2C5NB 3TW6A 2PHGA 2BS2A 4CFWB 2EUFA 4BY1X 4QSHA 4FM4B 4ELJA 3BG3A 3H4CA 2I40B 4YOSA 4YOOA 3BG5A 5FGKB 2DXCB 5LQFB 2WFYB 4IMYB 4OGRB 1FVVB 3QYHB 2I53A 4JX6A 2ZCFB 4NSTB 4CFNB 2C5XB 3QYGB 2WJ9A 1H1RB 1H27B 3PO3S 3DTOA 3WVDB 1H4LD 2WMAB 4OB1B 5LMKB 4CFVB 4BBSM 4ROEA 4M6VA 2UZLB 1H26B 2W96A 3GTMS 1FINB 2ZPGB 2IN3A 4OR5B 1GUXB 3BLRB 3K7AM 4I3ZB 1QLBA 2W9ZA 4TTHA 4KRDB 4EOMB 2WEVB 2CZ1B 4Z6YA 1JOWA 3DDPB 3DOGB 3QYBA 2UZEB 1E9HB 2JGZB 2D0QB 1TD6A 5BNJB 2IW6B 3QYEA 1P5EB 4AKGA 2DPPB 3NDQA 4F7LB 4BCHB 5IDPB 3EJ1B 4HLQA 3HZJA 1VINA 3MY5B 4EORB 4BCFB 3M03A 2CCIB 1OKWB 5ACBA 1UGPB 4FX3B 4BCKB 2ZZDB 4MIMA 4UN0A 2DD4B 3BHUB 2QDYB 2IW9B 1G3NC 3QZ5B 1O9KA 3A8HB 2WIHB 4HNTA 1OIUB 3BHVB 3TN8B 1UGQB 3KHIA 4BCMD 2WMBB 3A8OB 1FKMA 1URCB 3HBLA 2LW4A 2BS3A 1UNLD 2ZPIB 3QHWB 4ELLA 4F6SB 3WVEB 3VKGA 1H24B 5CEIB 5L2WB 1AD6A 4YOZA 5DQVA 1H1QB 4OB2B 3HHTB 4BCND 3DDQB 1H28B 2F2CA 3EOCB 3TNWB 2CJMB 1GY3B 1BU2A 2QGSA 3MY1B 4CFUD 2ZPHB 3POMA 4YC3B 5HBJB 1N4MA 2W99A 4G6LB 2PK9B 4BXXX 4BCMB 2IW8B 5I5ZB 3TW7A 3F5XB 2C4GB 3X26B 4ZGJB 3BHTB 3A8GB 4CFXB 4II5B 3A8MB 1W98B 1E7PA 1OL2B 2WXVB 4CXAB 2UUEB 3LQ5B 1VYWB 5HQ0B 1ZP2A 4AKHA 3QWLA 1H1SB 1OL1B 4F7SB 4EOLB 4BCNB 3BLQB 4LOCA 4EOKB 4NC6A 4HL4A 4F7NB 1H25B 4CFUB 2BS4A 1C9BA 4ROCA 2PK2A 4BCQD 3QZ9B 2G9XB 2G77A 1KXUA
chains in the Genus database with same CATH topology
2DXCB 3QXEB 2DXBB 1UGQB 3KHIA 2CZ7B 3QYHB 3A8OB 1FKMA 1UGRB 4JX6A 2ZCFB 3HBLA 2CZ6B 2BS3A 1IREB 3QYGB 2WJ9A 2ZPIB 3WVEB 3VKGA 3WVDB 4OB1B 4BBRM 3X24B 4MFEA 4BBSM 1AHJB 4OB2B 3X20B 3HHTB 2CYZB 4M6VA 3VYHB 2ZPEB 3DL1A 4JX5A 3A8LB 2QF7A 3X28B 2ZPGB 4HNUA 3VKHA 2ZPHB 4HNVA 3BG9A 3X25B 2ZPFB 1QLBA 2KR6A 4OB3B 5EJCA 2CZ1B 4ZGEB 4Z6YA 3TW7A 3X26B 4ZGJB 4OB0B 3A8GB 2DD5B 3QYBA 4AI6A 2D0QB 2QQ8A 3A8MB 2QDJA 1E7PA 3QYEA 1UGSB 4AKGA 4JX4A 2DPPB 4AKHA 4HLQA 3HZJA 3QWLA 1V29B 2CZ0B 2KMGA 2QFZA 4LOCA 4NC6A 4HL4A 4AKIA 3HO8A 1UGPB 3VYGB 4ZGDB 2ZPBB 2ZZDB 4MIMA 2BS4A 2AHJB 3HB9A 2DD4B 3TW6A 2BS2A 2QDYB 3QZ9B 4QSHA 4FM4B 4ELJA 3BG3A 3H4CA 3QZ5B 4MFDA 3A8HB 2G77A 4HNTA 3BG5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CZ1 B;  2DXC B;  3QXE B;  2DXB B;  1UGQ B;  1AHJ B;  4ZGE B;  4OB2 B;  3X20 B;  3HHT B;  3X26 B;  2CZ7 B;  2CYZ B;  3QYH B;  4ZGJ B;  3VYH B;  2ZPE B;  4OB0 B;  3A8G B;  3A8O B;  1UGP B;  2DD5 B;  3VYG B;  4ZGD B;  2ZPB B;  1UGR B;  2D0Q B;  2ZZD B;  2ZCF B;  3A8M B;  3A8L B;  2AHJ B;  2CZ6 B;  3X28 B;  2DD4 B;  2ZPG B;  1IRE B;  3QYG B;  1UGS B;  2ZPI B;  2DPP B;  2QDY B;  2ZPH B;  3QZ9 B;  4FM4 B;  3WVE B;  3WVD B;  3X25 B;  2ZPF B;  3QZ5 B;  1V29 B;  3A8H B;  4OB1 B;  2CZ0 B;  4OB3 B;  3X24 B; 
#chains in the Genus database with same CATH topology
 3QXE B;  3BLH B;  2PJQ A;  4CFM B;  3DJB A;  1UNG D;  5IF1 B;  2CZ6 B;  2C6T B;  3RGF B;  2IVX A;  1JSU B;  4EOI B;  4F6U B;  4BBR M;  3X24 B;  2WIP B;  5HVY B;  3DL1 A;  5HBH B;  5ICP B;  4F70 B;  3X28 B;  4EOQ B;  2UZB B;  4HNU A;  3VKH A;  4CRL B;  4HNV A;  5DQW A;  1ENW A;  2R7G A;  2KR6 A;  1O9K B;  4BCJ B;  1QMZ B;  1PKD B;  4ZGE B;  4BCO B;  2X1N B;  2DME A;  2UZD B;  2DD5 B;  1OIY B;  3TNH B;  2C5O B;  4JX4 A;  1H1P B;  4BY7 X;  1OI9 B;  2C5V B;  2CZ0 B;  2KMG A;  3QHR B;  2QFZ A;  4EOO B;  4EC8 B;  5HNB B;  1UNH D;  5IHY A;  2ZPB B;  3EID B;  3O0G D;  3HB9 A;  5HBE B;  1AIS B;  1GUX A;  5IDN B;  4MFD A;  2W2H A;  4EOJ B;  2DXB B;  1JKW A;  2WPA B;  2CZ7 B;  2WHB B;  2PMI B;  1UGR B;  2CCH B;  2B9R A;  4EOS B;  1IRE B;  1F5Q B;  1VOL A;  4EOP B;  4EC9 B;  4MFE A;  3G33 B;  1AHJ B;  3X20 B;  5EFQ B;  2BKZ B;  2CYZ B;  3MIA B;  3VYH B;  2ZPE B;  1JST B;  4ROD A;  3MI9 B;  1GH6 B;  4JX5 A;  3A8L B;  2W9F A;  4BCG B;  2QF7 A;  3BG9 A;  3X25 B;  2ZPF B;  4OB3 B;  5EJC A;  3B57 A;  2V22 B;  3TNI B;  4OB0 B;  4AI6 A;  2QQ8 A;  2QDJ A;  4F6W B;  4BCQ B;  1TFB A;  1UGS B;  1D3U B;  5CYI B;  1V29 B;  4Y72 B;  1XO2 A;  4EON B;  4F7J B;  4BCP B;  4AKI A;  2BPM B;  3HO8 A;  3VYG B;  1OGU B;  4KRC B;  4ZGD B;  1OKV B;  4BCI B;  2AHJ B;  2C5N B;  3TW6 A;  2PHG A;  2BS2 A;  4CFW B;  2EUF A;  4BY1 X;  4QSH A;  4FM4 B;  4ELJ A;  3BG3 A;  3H4C A;  2I40 B;  4YOS A;  4YOO A;  3BG5 A;  5FGK B;  2DXC B;  5LQF B;  2WFY B;  4IMY B;  4OGR B;  1FVV B;  3QYH B;  2I53 A;  4JX6 A;  2ZCF B;  4NST B;  4CFN B;  2C5X B;  3QYG B;  2WJ9 A;  1H1R B;  1H27 B;  3PO3 S;  3DTO A;  3WVD B;  1H4L D;  2WMA B;  4OB1 B;  5LMK B;  4CFV B;  4BBS M;  4ROE A;  4M6V A;  2UZL B;  1H26 B;  2W96 A;  3GTM S;  1FIN B;  2ZPG B;  2IN3 A;  4OR5 B;  1GUX B;  3BLR B;  3K7A M;  4I3Z B;  1QLB A;  2W9Z A;  4TTH A;  4KRD B;  4EOM B;  2WEV B;  2CZ1 B;  4Z6Y A;  1JOW A;  3DDP B;  3DOG B;  3QYB A;  2UZE B;  1E9H B;  2JGZ B;  2D0Q B;  1TD6 A;  5BNJ B;  2IW6 B;  3QYE A;  1P5E B;  4AKG A;  2DPP B;  3NDQ A;  4F7L B;  4BCH B;  5IDP B;  3EJ1 B;  4HLQ A;  3HZJ A;  1VIN A;  3MY5 B;  4EOR B;  4BCF B;  3M03 A;  2CCI B;  1OKW B;  5ACB A;  1UGP B;  4FX3 B;  4BCK B;  2ZZD B;  4MIM A;  4UN0 A;  2DD4 B;  3BHU B;  2QDY B;  2IW9 B;  1G3N C;  3QZ5 B;  1O9K A;  3A8H B;  2WIH B;  4HNT A;  1OIU B;  3BHV B;  3TN8 B;  1UGQ B;  3KHI A;  4BCM D;  2WMB B;  3A8O B;  1FKM A;  1URC B;  3HBL A;  2LW4 A;  2BS3 A;  1UNL D;  2ZPI B;  3QHW B;  4ELL A;  4F6S B;  3WVE B;  3VKG A;  1H24 B;  5CEI B;  5L2W B;  1AD6 A;  4YOZ A;  5DQV A;  1H1Q B;  4OB2 B;  3HHT B;  4BCN D;  3DDQ B;  1H28 B;  2F2C A;  3EOC B;  3TNW B;  2CJM B;  1GY3 B;  1BU2 A;  2QGS A;  3MY1 B;  4CFU D;  2ZPH B;  3POM A;  4YC3 B;  5HBJ B;  1N4M A;  2W99 A;  4G6L B;  2PK9 B;  4BXX X;  4BCM B;  2IW8 B;  5I5Z B;  3TW7 A;  3F5X B;  2C4G B;  3X26 B;  4ZGJ B;  3BHT B;  3A8G B;  4CFX B;  4II5 B;  3A8M B;  1W98 B;  1E7P A;  1OL2 B;  2WXV B;  4CXA B;  2UUE B;  3LQ5 B;  1VYW B;  5HQ0 B;  1ZP2 A;  4AKH A;  3QWL A;  1H1S B;  1OL1 B;  4F7S B;  4EOL B;  4BCN B;  3BLQ B;  4LOC A;  4EOK B;  4NC6 A;  4HL4 A;  4F7N B;  1H25 B;  4CFU B;  2BS4 A;  1C9B A;  4ROC A;  2PK2 A;  4BCQ D;  3QZ9 B;  2G9X B;  2G77 A;  1KXU A; 
#chains in the Genus database with same CATH homology
 2DXC B;  3QXE B;  2DXB B;  1UGQ B;  3KHI A;  2CZ7 B;  3QYH B;  3A8O B;  1FKM A;  1UGR B;  4JX6 A;  2ZCF B;  3HBL A;  2CZ6 B;  2BS3 A;  1IRE B;  3QYG B;  2WJ9 A;  2ZPI B;  3WVE B;  3VKG A;  3WVD B;  4OB1 B;  4BBR M;  3X24 B;  4MFE A;  4BBS M;  1AHJ B;  4OB2 B;  3X20 B;  3HHT B;  2CYZ B;  4M6V A;  3VYH B;  2ZPE B;  3DL1 A;  4JX5 A;  3A8L B;  2QF7 A;  3X28 B;  2ZPG B;  4HNU A;  3VKH A;  2ZPH B;  4HNV A;  3BG9 A;  3X25 B;  2ZPF B;  1QLB A;  2KR6 A;  4OB3 B;  5EJC A;  2CZ1 B;  4ZGE B;  4Z6Y A;  3TW7 A;  3X26 B;  4ZGJ B;  4OB0 B;  3A8G B;  2DD5 B;  3QYB A;  4AI6 A;  2D0Q B;  2QQ8 A;  3A8M B;  2QDJ A;  1E7P A;  3QYE A;  1UGS B;  4AKG A;  4JX4 A;  2DPP B;  4AKH A;  4HLQ A;  3HZJ A;  3QWL A;  1V29 B;  2CZ0 B;  2KMG A;  2QFZ A;  4LOC A;  4NC6 A;  4HL4 A;  4AKI A;  3HO8 A;  1UGP B;  3VYG B;  4ZGD B;  2ZPB B;  2ZZD B;  4MIM A;  2BS4 A;  2AHJ B;  3HB9 A;  2DD4 B;  3TW6 A;  2BS2 A;  2QDY B;  3QZ9 B;  4QSH A;  4FM4 B;  4ELJ A;  3BG3 A;  3H4C A;  3QZ5 B;  4MFD A;  3A8H B;  2G77 A;  4HNT A;  3BG5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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