2DXCB

Recombinant thiocyanate hydrolase, fully-matured form
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
152
structure length
152
Chain Sequence
SSIREEVHRHLGTVALMQPALHQQTHAPAPTEITHTLFRAYTRVPHDVGGEADVPIEYHEKEEEIWELNTFATCECLAWRGVWTAEERRRKQNCDVGQTVYLGMPYYGRWLLTAARILVDKQFVTLTELHNKIVEMRERVASGQGLGEYLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification
pubmed doi rcsb
molecule tags Hydrolase
source organism Thiobacillus thioparus
molecule keywords Thiocyanate hydrolase subunit alpha
total genus 47
structure length 152
sequence length 152
chains with identical sequence E, H, K
ec nomenclature ec 3.5.5.8: Thiocyanate hydrolase.
pdb deposition date 2006-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF02211 NHase_beta Nitrile hydratase beta subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.20 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2dxcB00
3X20B 3QYHB 3QZ5B 4OB3B 3QYGB 3A8MB 3A8OB 2AHJB 3HHTB 3X26B 1UGRB 1UGQB 3QZ9B 4ZGDB 2DPPB 1V29B 2ZPBB 3QXEB 2QDYB 4OB1B 3VYHB 2ZPIB 4OB0B 2DD5B 2CYZB 2ZCFB 4OB2B 1UGPB 2CZ1B 3WVDB 4ZGEB 4ZGJB 1UGSB 3WVEB 1IREB 2CZ7B 2ZPHB 2ZZDB 3A8GB 1AHJB 2ZPEB 2ZPFB 2ZPGB 4FM4B 2D0QB 2DXCB 3X24B 3X25B 3VYGB 2CZ0B 2DXBB 3A8LB 3A8HB 3X28B 2CZ6B 2DD4B
chains in the Genus database with same CATH superfamily
1VYWB 1H26B 4RODA 4EOKB 5ICPB 2IW6B 4MFDA 3X26B 3MY1B 4BCNB 3QHRB 5L2WB 4EOLB 1VOLA 4CFUD 5HNBB 3WVDB 2BKZB 4EOIB 4EC8B 3A8GB 2WHBB 1XO2A 2G9XB 2D0QB 5HBJB 1H24B 2C6TB 1UNLD 4MFEA 2AHJB 2C5NB 2CCIB 4ZGDB 4EOOB 3QHWB 1OGUB 3DTOA 2BS3A 2CJMB 1OKWB 4TTHA 1H1QB 3BHUB 4AKIA 4OB3B 4Z6YA 3DJBA 3HB9A 4CRLB 4F7SB 2UUEB 2W2HA 3QYEA 3WVEB 2CZ7B 1E9HB 2I53A 1H28B 1H25B 3VYGB 4MIMA 1N4MA 3X28B 3HZJA 3QYGB 4ROCA 4I3ZB 2WPAB 1OIUB 2EUFA 2DD5B 2BS4A 1UNHD 4CFWB 4HNTA 3QWLA 3EIDB 3MI9B 4OB0B 2CZ6B 4FM4B 4BCIB 3RGFB 5DQWA 4II5B 3EOCB 3GTMS 2DPPB 4HL4A 1UNGD 2ZPIB 1H1SB 2ZPHB 5FGKB 4LOCA 4AKGA 3DDQB 4BXXX 4F6SB 5HBEB 3MIAB 2C5XB 1OL2B 2QDYB 4ROEA 4ELLA 1GUXB 1H4LD 5LMKB 3KHIA 4CFMB 2ZCFB 1JSTB 1UGPB 4AKHA 4AI6A 4IMYB 2UZBB 1O9KA 3EJ1B 4CFNB 5BNJB 3TW7A 2PJQA 4BBRM 5HQ0B 3F5XB 2JGZB 1IREB 4BY7X 2CCHB 2WXVB 2DD4B 5I5ZB 3BHVB 2UZLB 2QFZA 4EOQB 5IHYA 1H1PB 4BCMD 3PO3S 2IW9B 4NC6A 1OIYB 3LQ5B 4BCKB 2ZPGB 4BBSM 2DXCB 4ELJA 2W99A 2CZ0B 3TNIB 1AISB 3TNWB 4YOZA 2WEVB 2C4GB 2W96A 4FX3B 4CFUB 3A8MB 4BCHB 2ZPBB 2PHGA 3B57A 3VKHA 3VYHB 2UZEB 4EOSB 3HO8A 5HBHB 3BHTB 2ZPFB 3BG5A 5ACBA 4F7LB 1E7PA 5IF1B 1C9BA 4BY1X 1D3UB 1FVVB 2QGSA 3HBLA 1OI9B 4JX5A 3TW6A 1ENWA 2WIHB 3O0GD 2F2CA 4EORB 2IVXA 3DL1A 4KRDB 1QMZB 2KR6A 3X20B 2G77A 1AD6A 3QYBA 4F70B 1GUXA 1TD6A 2QDJA 4F6UB 1JOWA 4OGRB 2DXBB 3BG3A 1VINA 2C5OB 5IDNB 2X1NB 2W9ZA 3QZ5B 5IDPB 2WFYB 3HHTB 1H27B 1F5QB 3QZ9B 4YOSA 4BCPB 2B9RA 1GH6B 4ZGEB 4ZGJB 2PMIB 1UGSB 4NSTB 5HVYB 2PK2A 3K7AM 4OR5B 4BCJB 2I40B 1O9KB 4BCQD 4JX4A 2WIPB 5CEIB 3BLRB 3A8OB 3M03A 4CFVB 1URCB 3MY5B 3VKGA 1H1RB 3QXEB 1P5EB 3TNHB 2CYZB 4BCFB 5CYIB 1FINB 2WMAB 3DDPB 1AHJB 1BU2A 1PKDB 4CXAB 5DQVA 3A8LB 3QYHB 2LW4A 3G33B 2W9FA 3NDQA 4G6LB 4M6VA 4OB1B 3H4CA 2UZDB 4OB2B 2CZ1B 2QF7A 3BLQB 4BCOB 4BCND 1JKWA 2PK9B 1OKVB 2ZZDB 2DMEA 3X25B 3TN8B 2BS2A 4HNVA 1FKMA 2V22B 4HNUA 4Y72B 3DOGB 4HLQA 4YC3B 3POMA 4EC9B 1UGRB 1UGQB 1ZP2A 3BLHB 2KMGA 4CFXB 4UN0A 1QLBA 1OL1B 2IW8B 4EOPB 2BPMB 4F6WB 4YOOA 4BCQB 2R7GA 2ZPEB 1JSUB 5LQFB 1G3NC 4BCMB 4EOMB 1V29B 2WJ9A 1W98B 2IN3A 5EJCA 3BG9A 2WMBB 4EOJB 1TFBA 5EFQB 4EONB 2C5VB 4KRCB 1GY3B 4F7NB 3X24B 4F7JB 2QQ8A 4BCGB 3A8HB 4JX6A 1KXUA 4QSHA
chains in the Genus database with same CATH topology
4JX4A 3A8MB 3A8OB 4MFDA 3X26B 2DPPB 2ZPBB 3VKGA 3QXEB 3VKHA 4HL4A 3VYHB 2ZPIB 2CYZB 3WVDB 3HO8A 2ZPHB 3A8GB 1AHJB 2ZPFB 3BG5A 4LOCA 4AKGA 2D0QB 3A8LB 1E7PA 3HBLA 3QYHB 4MFEA 2AHJB 4ZGDB 4JX5A 3TW6A 2QDYB 4M6VA 4OB1B 3H4CA 3KHIA 4OB2B 2ZCFB 1UGPB 2CZ1B 2QF7A 4AKHA 2BS3A 3DL1A 2ZZDB 4AI6A 4AKIA 3X25B 2KR6A 2BS2A 4HNVA 1FKMA 4HNUA 3X20B 2G77A 4OB3B 4Z6YA 4HLQA 1UGRB 1UGQB 3QYBA 2KMGA 3TW7A 3HB9A 1QLBA 4BBRM 2QDJA 3QYEA 3WVEB 1IREB 2CZ7B 2ZPEB 4HNTA 3VYGB 2DXBB 3BG3A 4MIMA 3X28B 3HZJA 2DD4B 3QZ5B 3QYGB 2QFZA 3HHTB 3QZ9B 1V29B 2WJ9A 5EJCA 3BG9A 4OB0B 2DD5B 4NC6A 4ZGEB 4ZGJB 1UGSB 2BS4A 2ZPGB 4BBSM 2DXCB 4ELJA 3X24B 2QQ8A 2CZ0B 3A8HB 4JX6A 3QWLA 4QSHA 2CZ6B 4FM4B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X20 B;  3QYH B;  3QZ5 B;  4OB3 B;  3QYG B;  3A8M B;  3A8O B;  2AHJ B;  3HHT B;  3X26 B;  1UGR B;  1UGQ B;  3QZ9 B;  4ZGD B;  2DPP B;  1V29 B;  2ZPB B;  3QXE B;  2QDY B;  4OB1 B;  3VYH B;  2ZPI B;  4OB0 B;  2DD5 B;  2CYZ B;  2ZCF B;  4OB2 B;  1UGP B;  2CZ1 B;  3WVD B;  4ZGE B;  4ZGJ B;  1UGS B;  3WVE B;  1IRE B;  2CZ7 B;  2ZPH B;  2ZZD B;  3A8G B;  1AHJ B;  2ZPE B;  2ZPF B;  2ZPG B;  4FM4 B;  2D0Q B;  2DXC B;  3X24 B;  3X25 B;  3VYG B;  2CZ0 B;  2DXB B;  3A8L B;  3A8H B;  3X28 B;  2CZ6 B;  2DD4 B; 
#chains in the Genus database with same CATH topology
 1VYW B;  1H26 B;  4ROD A;  4EOK B;  5ICP B;  2IW6 B;  4MFD A;  3X26 B;  3MY1 B;  4BCN B;  3QHR B;  5L2W B;  4EOL B;  1VOL A;  4CFU D;  5HNB B;  3WVD B;  2BKZ B;  4EOI B;  4EC8 B;  3A8G B;  2WHB B;  1XO2 A;  2G9X B;  2D0Q B;  5HBJ B;  1H24 B;  2C6T B;  1UNL D;  4MFE A;  2AHJ B;  2C5N B;  2CCI B;  4ZGD B;  4EOO B;  3QHW B;  1OGU B;  3DTO A;  2BS3 A;  2CJM B;  1OKW B;  4TTH A;  1H1Q B;  3BHU B;  4AKI A;  4OB3 B;  4Z6Y A;  3DJB A;  3HB9 A;  4CRL B;  4F7S B;  2UUE B;  2W2H A;  3QYE A;  3WVE B;  2CZ7 B;  1E9H B;  2I53 A;  1H28 B;  1H25 B;  3VYG B;  4MIM A;  1N4M A;  3X28 B;  3HZJ A;  3QYG B;  4ROC A;  4I3Z B;  2WPA B;  1OIU B;  2EUF A;  2DD5 B;  2BS4 A;  1UNH D;  4CFW B;  4HNT A;  3QWL A;  3EID B;  3MI9 B;  4OB0 B;  2CZ6 B;  4FM4 B;  4BCI B;  3RGF B;  5DQW A;  4II5 B;  3EOC B;  3GTM S;  2DPP B;  4HL4 A;  1UNG D;  2ZPI B;  1H1S B;  2ZPH B;  5FGK B;  4LOC A;  4AKG A;  3DDQ B;  4BXX X;  4F6S B;  5HBE B;  3MIA B;  2C5X B;  1OL2 B;  2QDY B;  4ROE A;  4ELL A;  1GUX B;  1H4L D;  5LMK B;  3KHI A;  4CFM B;  2ZCF B;  1JST B;  1UGP B;  4AKH A;  4AI6 A;  4IMY B;  2UZB B;  1O9K A;  3EJ1 B;  4CFN B;  5BNJ B;  3TW7 A;  2PJQ A;  4BBR M;  5HQ0 B;  3F5X B;  2JGZ B;  1IRE B;  4BY7 X;  2CCH B;  2WXV B;  2DD4 B;  5I5Z B;  3BHV B;  2UZL B;  2QFZ A;  4EOQ B;  5IHY A;  1H1P B;  4BCM D;  3PO3 S;  2IW9 B;  4NC6 A;  1OIY B;  3LQ5 B;  4BCK B;  2ZPG B;  4BBS M;  2DXC B;  4ELJ A;  2W99 A;  2CZ0 B;  3TNI B;  1AIS B;  3TNW B;  4YOZ A;  2WEV B;  2C4G B;  2W96 A;  4FX3 B;  4CFU B;  3A8M B;  4BCH B;  2ZPB B;  2PHG A;  3B57 A;  3VKH A;  3VYH B;  2UZE B;  4EOS B;  3HO8 A;  5HBH B;  3BHT B;  2ZPF B;  3BG5 A;  5ACB A;  4F7L B;  1E7P A;  5IF1 B;  1C9B A;  4BY1 X;  1D3U B;  1FVV B;  2QGS A;  3HBL A;  1OI9 B;  4JX5 A;  3TW6 A;  1ENW A;  2WIH B;  3O0G D;  2F2C A;  4EOR B;  2IVX A;  3DL1 A;  4KRD B;  1QMZ B;  2KR6 A;  3X20 B;  2G77 A;  1AD6 A;  3QYB A;  4F70 B;  1GUX A;  1TD6 A;  2QDJ A;  4F6U B;  1JOW A;  4OGR B;  2DXB B;  3BG3 A;  1VIN A;  2C5O B;  5IDN B;  2X1N B;  2W9Z A;  3QZ5 B;  5IDP B;  2WFY B;  3HHT B;  1H27 B;  1F5Q B;  3QZ9 B;  4YOS A;  4BCP B;  2B9R A;  1GH6 B;  4ZGE B;  4ZGJ B;  2PMI B;  1UGS B;  4NST B;  5HVY B;  2PK2 A;  3K7A M;  4OR5 B;  4BCJ B;  2I40 B;  1O9K B;  4BCQ D;  4JX4 A;  2WIP B;  5CEI B;  3BLR B;  3A8O B;  3M03 A;  4CFV B;  1URC B;  3MY5 B;  3VKG A;  1H1R B;  3QXE B;  1P5E B;  3TNH B;  2CYZ B;  4BCF B;  5CYI B;  1FIN B;  2WMA B;  3DDP B;  1AHJ B;  1BU2 A;  1PKD B;  4CXA B;  5DQV A;  3A8L B;  3QYH B;  2LW4 A;  3G33 B;  2W9F A;  3NDQ A;  4G6L B;  4M6V A;  4OB1 B;  3H4C A;  2UZD B;  4OB2 B;  2CZ1 B;  2QF7 A;  3BLQ B;  4BCO B;  4BCN D;  1JKW A;  2PK9 B;  1OKV B;  2ZZD B;  2DME A;  3X25 B;  3TN8 B;  2BS2 A;  4HNV A;  1FKM A;  2V22 B;  4HNU A;  4Y72 B;  3DOG B;  4HLQ A;  4YC3 B;  3POM A;  4EC9 B;  1UGR B;  1UGQ B;  1ZP2 A;  3BLH B;  2KMG A;  4CFX B;  4UN0 A;  1QLB A;  1OL1 B;  2IW8 B;  4EOP B;  2BPM B;  4F6W B;  4YOO A;  4BCQ B;  2R7G A;  2ZPE B;  1JSU B;  5LQF B;  1G3N C;  4BCM B;  4EOM B;  1V29 B;  2WJ9 A;  1W98 B;  2IN3 A;  5EJC A;  3BG9 A;  2WMB B;  4EOJ B;  1TFB A;  5EFQ B;  4EON B;  2C5V B;  4KRC B;  1GY3 B;  4F7N B;  3X24 B;  4F7J B;  2QQ8 A;  4BCG B;  3A8H B;  4JX6 A;  1KXU A;  4QSH A; 
#chains in the Genus database with same CATH homology
 4JX4 A;  3A8M B;  3A8O B;  4MFD A;  3X26 B;  2DPP B;  2ZPB B;  3VKG A;  3QXE B;  3VKH A;  4HL4 A;  3VYH B;  2ZPI B;  2CYZ B;  3WVD B;  3HO8 A;  2ZPH B;  3A8G B;  1AHJ B;  2ZPF B;  3BG5 A;  4LOC A;  4AKG A;  2D0Q B;  3A8L B;  1E7P A;  3HBL A;  3QYH B;  4MFE A;  2AHJ B;  4ZGD B;  4JX5 A;  3TW6 A;  2QDY B;  4M6V A;  4OB1 B;  3H4C A;  3KHI A;  4OB2 B;  2ZCF B;  1UGP B;  2CZ1 B;  2QF7 A;  4AKH A;  2BS3 A;  3DL1 A;  2ZZD B;  4AI6 A;  4AKI A;  3X25 B;  2KR6 A;  2BS2 A;  4HNV A;  1FKM A;  4HNU A;  3X20 B;  2G77 A;  4OB3 B;  4Z6Y A;  4HLQ A;  1UGR B;  1UGQ B;  3QYB A;  2KMG A;  3TW7 A;  3HB9 A;  1QLB A;  4BBR M;  2QDJ A;  3QYE A;  3WVE B;  1IRE B;  2CZ7 B;  2ZPE B;  4HNT A;  3VYG B;  2DXB B;  3BG3 A;  4MIM A;  3X28 B;  3HZJ A;  2DD4 B;  3QZ5 B;  3QYG B;  2QFZ A;  3HHT B;  3QZ9 B;  1V29 B;  2WJ9 A;  5EJC A;  3BG9 A;  4OB0 B;  2DD5 B;  4NC6 A;  4ZGE B;  4ZGJ B;  1UGS B;  2BS4 A;  2ZPG B;  4BBS M;  2DXC B;  4ELJ A;  3X24 B;  2QQ8 A;  2CZ0 B;  3A8H B;  4JX6 A;  3QWL A;  4QSH A;  2CZ6 B;  4FM4 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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